YDHK - ECOLI - GREMLIN Contacts

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YDHK - Uncharacterized transporter YdhK

UniProt:	P76186	Sequences: MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLDEPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSAWLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGILCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETTDAIRAAHEGVIGQILTMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREILEQLLTALASSQTDVYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHRLQSGVDDHTRLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLAAISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLATMQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFAILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARRWLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATLEELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13945
Length:	670 (625)
Sequences:	956 (714)
Seq/√Len:	28.6

ECOLI - YDHK AAEB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
105_G	363_G	5.434	1.00
36_T	437_L	4.717	1.00
105_G	367_F	4.636	1.00
109_W	356_N	4.344	1.00
131_I	394_I	3.960	1.00
72_I	157_I	3.800	1.00
28_T	32_C	3.780	1.00
446_P	450_T	3.667	1.00
103_W	107_C	3.555	1.00
101_S	371_M	3.544	1.00
37_V	158_V	3.349	1.00
124_L	127_Y	3.339	1.00
33_L	162_C	3.281	1.00
603_I	610_M	3.149	1.00
609_V	613_R	3.104	1.00
424_F	489_F	3.003	1.00
317_L	334_L	2.984	1.00
97_L	374_G	2.928	1.00
529_D	552_H	2.803	1.00
323_L	326_Q	2.700	1.00
198_W	201_E	2.698	1.00
437_L	441_L	2.682	1.00
628_Q	631_C	2.675	1.00
316_R	320_F	2.543	0.99
423_S	489_F	2.537	0.99
600_D	603_I	2.528	0.99
623_T	627_L	2.518	0.99
26_R	61_V	2.503	0.99
89_T	99_S	2.476	0.99
165_M	169_I	2.443	0.99
529_D	548_L	2.440	0.99
31_M	54_A	2.410	0.99
130_A	393_A	2.360	0.99
132_I	149_A	2.324	0.99
289_D	292_T	2.310	0.99
355_D	521_R	2.289	0.99
323_L	334_L	2.262	0.98
157_I	161_L	2.258	0.98
278_Q	296_I	2.252	0.98
434_I	443_F	2.228	0.98
150_Q	154_C	2.176	0.98
24_A	54_A	2.164	0.98
79_A	83_L	2.156	0.98
96_F	160_I	2.137	0.98
32_C	441_L	2.128	0.98
322_R	334_L	2.109	0.98
624_L	628_Q	2.107	0.98
373_I	392_A	2.104	0.97
319_Y	323_L	2.083	0.97
71_R	120_Y	2.082	0.97
596_S	600_D	2.077	0.97
23_Y	456_L	2.063	0.97
79_A	153_V	2.040	0.97
607_R	610_M	2.030	0.97
573_V	579_S	2.009	0.97
30_A	53_A	1.978	0.96
303_T	306_A	1.964	0.96
317_L	323_L	1.964	0.96
103_W	125_A	1.963	0.96
316_R	330_E	1.954	0.96
312_A	320_F	1.952	0.96
94_W	375_A	1.942	0.96
73_A	76_L	1.942	0.96
627_L	631_C	1.931	0.96
316_R	319_Y	1.930	0.96
623_T	630_I	1.923	0.96
319_Y	334_L	1.921	0.96
290_V	293_V	1.906	0.95
316_R	334_L	1.903	0.95
120_Y	124_L	1.899	0.95
422_F	468_L	1.896	0.95
54_A	452_Q	1.891	0.95
55_V	456_L	1.888	0.95
125_A	380_S	1.884	0.95
596_S	603_I	1.873	0.95
623_T	628_Q	1.859	0.95
103_W	127_Y	1.852	0.95
319_Y	326_Q	1.844	0.95
109_W	363_G	1.829	0.94
599_R	603_I	1.827	0.94
420_S	493_N	1.807	0.94
417_V	497_I	1.804	0.94
134_F	374_G	1.800	0.94
385_G	405_P	1.795	0.94
341_H	344_L	1.791	0.94
292_T	296_I	1.790	0.94
79_A	149_A	1.786	0.94
606_L	610_M	1.783	0.93
29_I	445_F	1.781	0.93
300_L	304_N	1.780	0.93
73_A	121_A	1.768	0.93
615_V	619_S	1.731	0.92
602_C	609_V	1.730	0.92
320_F	325_L	1.729	0.92
294_A	298_A	1.728	0.92
458_M	461_F	1.715	0.92
71_R	127_Y	1.691	0.92
289_D	294_A	1.690	0.91
120_Y	127_Y	1.684	0.91
55_V	394_I	1.680	0.91
312_A	316_R	1.671	0.91
331_L	335_Q	1.669	0.91
48_W	93_P	1.662	0.91
603_I	607_R	1.662	0.91
616_Q	619_S	1.649	0.90
315_Q	327_S	1.637	0.90
71_R	75_S	1.635	0.90
320_F	334_L	1.616	0.90
35_L	553_V	1.610	0.89
602_C	606_L	1.608	0.89
26_R	170_L	1.593	0.89
289_D	304_N	1.591	0.89
75_S	120_Y	1.583	0.89
278_Q	282_A	1.572	0.88
301_R	304_N	1.571	0.88
576_L	579_S	1.563	0.88
326_Q	330_E	1.562	0.88
61_V	155_E	1.558	0.88
417_V	421_L	1.557	0.88
37_V	162_C	1.535	0.87
377_S	385_G	1.530	0.87
623_T	634_L	1.521	0.86
85_L	99_S	1.518	0.86
334_L	338_V	1.515	0.86
396_C	475_F	1.513	0.86
52_S	142_A	1.510	0.86
52_S	156_V	1.508	0.86
100_M	129_A	1.506	0.86
126_G	398_L	1.505	0.86
136_M	148_I	1.503	0.86
230_S	247_Q	1.498	0.86
165_M	296_I	1.497	0.86
323_L	331_L	1.482	0.85
330_E	338_V	1.481	0.85
112_A	362_S	1.480	0.85
382_W	385_G	1.474	0.85
63_G	452_Q	1.473	0.85
230_S	480_N	1.473	0.85
619_S	623_T	1.467	0.84
107_C	129_A	1.467	0.84
624_L	631_C	1.462	0.84
48_W	155_E	1.460	0.84
110_A	456_L	1.450	0.84
368_C	604_S	1.449	0.84
626_E	631_C	1.441	0.83
619_S	631_C	1.433	0.83
634_L	638_H	1.427	0.83
29_I	170_L	1.405	0.82
26_R	172_S	1.403	0.82
230_S	256_S	1.392	0.81
369_T	372_M	1.384	0.81
398_L	470_V	1.371	0.80
317_L	320_F	1.369	0.80
316_R	326_Q	1.369	0.80
356_N	363_G	1.366	0.80
602_C	610_M	1.366	0.80
595_L	611_S	1.364	0.80
315_Q	324_Y	1.352	0.79
66_S	226_Q	1.351	0.79
320_F	330_E	1.350	0.79
489_F	493_N	1.349	0.79
422_F	425_V	1.346	0.79
610_M	613_R	1.346	0.79
172_S	377_S	1.344	0.79
385_G	491_N	1.342	0.79
320_F	338_V	1.342	0.79
598_V	607_R	1.341	0.78
317_L	339_D	1.338	0.78
283_L	297_I	1.336	0.78
38_A	55_V	1.335	0.78
440_F	444_L	1.329	0.78
631_C	635_A	1.317	0.77
127_Y	398_L	1.317	0.77
599_R	609_V	1.311	0.77
615_V	631_C	1.309	0.77
79_A	148_I	1.307	0.77
155_E	172_S	1.303	0.76
328_S	334_L	1.297	0.76
595_L	610_M	1.296	0.76
110_A	122_F	1.284	0.75
412_L	467_Q	1.282	0.75
115_T	166_M	1.282	0.75
289_D	293_V	1.281	0.75
617_Q	620_L	1.276	0.75
404_A	512_P	1.273	0.75
305_V	308_Y	1.273	0.75
398_L	503_A	1.273	0.75
426_V	430_L	1.272	0.75
320_F	331_L	1.252	0.73
297_I	301_R	1.252	0.73
155_E	229_W	1.244	0.73
596_S	607_R	1.243	0.73
602_C	613_R	1.237	0.73
108_T	397_V	1.236	0.72
599_R	605_L	1.229	0.72
375_A	379_A	1.224	0.72
31_M	50_M	1.224	0.72
183_L	244_L	1.223	0.72
327_S	337_G	1.218	0.71
475_F	493_N	1.216	0.71
595_L	599_R	1.216	0.71
82_A	131_I	1.212	0.71
445_F	449_A	1.211	0.71
151_A	154_C	1.211	0.71
583_W	586_R	1.207	0.71
620_L	624_L	1.207	0.71
122_F	155_E	1.206	0.71
202_T	277_E	1.204	0.70
425_V	429_G	1.202	0.70
363_G	439_Q	1.202	0.70
619_S	622_A	1.201	0.70
89_T	146_W	1.198	0.70
38_A	76_L	1.196	0.70
545_F	579_S	1.195	0.70
428_F	489_F	1.193	0.70
315_Q	318_R	1.190	0.70
528_R	603_I	1.189	0.69
431_M	500_V	1.187	0.69
52_S	582_V	1.178	0.69
323_L	338_V	1.173	0.68
327_S	334_L	1.172	0.68
373_I	388_A	1.171	0.68
615_V	623_T	1.169	0.68
122_F	229_W	1.169	0.68
319_Y	322_R	1.169	0.68
24_A	48_W	1.167	0.68
52_S	71_R	1.163	0.68
265_W	268_P	1.162	0.68
304_N	310_H	1.162	0.68
617_Q	621_A	1.159	0.67
103_W	126_G	1.158	0.67
107_C	127_Y	1.150	0.67
302_P	502_L	1.149	0.67
579_S	583_W	1.143	0.66
622_A	631_C	1.143	0.66
556_L	576_L	1.143	0.66
70_G	118_V	1.137	0.66
22_R	25_L	1.135	0.66
602_C	605_L	1.135	0.66
75_S	152_R	1.133	0.66
634_L	637_H	1.132	0.66
559_S	564_A	1.126	0.65
45_E	48_W	1.123	0.65
316_R	338_V	1.122	0.65
293_V	301_R	1.121	0.65
26_R	114_F	1.119	0.65
313_F	316_R	1.119	0.65
403_A	467_Q	1.112	0.64
602_C	607_R	1.111	0.64
130_A	504_W	1.110	0.64
417_V	611_S	1.109	0.64
315_Q	322_R	1.109	0.64
57_S	163_G	1.104	0.64
373_I	502_L	1.098	0.63
89_T	115_T	1.098	0.63
26_R	122_F	1.095	0.63
595_L	609_V	1.095	0.63
123_Q	415_T	1.093	0.63
54_A	58_F	1.090	0.63
33_L	388_A	1.088	0.62
289_D	297_I	1.088	0.62
111_C	381_Q	1.087	0.62
315_Q	323_L	1.081	0.62
621_A	628_Q	1.075	0.61
66_S	127_Y	1.072	0.61
327_S	331_L	1.071	0.61
388_A	499_G	1.070	0.61
55_V	124_L	1.068	0.61
52_S	135_P	1.065	0.61
52_S	465_W	1.064	0.61
187_H	213_V	1.058	0.60
112_A	365_R	1.057	0.60
70_G	147_D	1.055	0.60
123_Q	398_L	1.054	0.60
145_L	390_T	1.052	0.60
171_P	394_I	1.048	0.59
601_N	604_S	1.048	0.59
83_L	149_A	1.048	0.59
369_T	392_A	1.046	0.59
43_L	401_A	1.042	0.59
23_Y	35_L	1.042	0.59
93_P	137_V	1.040	0.59
71_R	124_L	1.040	0.59
128_T	152_R	1.039	0.59
100_M	442_L	1.036	0.59
387_N	390_T	1.036	0.59
339_D	497_I	1.036	0.59
165_M	317_L	1.034	0.58
306_A	309_R	1.034	0.58
299_P	310_H	1.032	0.58
422_F	472_M	1.031	0.58
224_R	229_W	1.030	0.58
388_A	498_V	1.028	0.58
415_T	451_M	1.026	0.58
34_A	49_A	1.024	0.58
53_A	499_G	1.021	0.57
197_L	283_L	1.020	0.57
167_M	175_D	1.019	0.57
58_F	472_M	1.017	0.57
290_V	300_L	1.016	0.57
124_L	156_V	1.015	0.57
597_R	601_N	1.011	0.57
57_S	70_G	1.011	0.57
155_E	378_I	1.009	0.57
313_F	334_L	1.007	0.56
54_A	155_E	1.005	0.56
607_R	613_R	1.004	0.56
47_Y	226_Q	1.003	0.56
158_V	284_A	1.002	0.56
23_Y	194_A	0.997	0.56
53_A	57_S	0.997	0.56
171_P	176_A	0.996	0.56
604_S	608_G	0.995	0.55
185_N	608_G	0.994	0.55
390_T	397_V	0.993	0.55
87_G	91_N	0.993	0.55
29_I	150_Q	0.993	0.55
549_T	552_H	0.992	0.55
317_L	328_S	0.992	0.55
82_A	505_L	0.992	0.55
365_R	507_F	0.991	0.55
50_M	229_W	0.991	0.55
34_A	159_G	0.988	0.55
400_S	512_P	0.988	0.55
189_R	192_E	0.987	0.55
471_F	496_K	0.986	0.55
325_L	337_G	0.985	0.55
81_A	103_W	0.985	0.55
399_Y	503_A	0.984	0.55
22_R	26_R	0.984	0.55
52_S	123_Q	0.982	0.54
377_S	382_W	0.980	0.54
63_G	545_F	0.980	0.54
34_A	39_Y	0.979	0.54
328_S	335_Q	0.978	0.54
117_N	365_R	0.977	0.54
128_T	522_H	0.975	0.54
606_L	609_V	0.971	0.54
252_T	255_I	0.970	0.54
599_R	607_R	0.970	0.54
169_I	461_F	0.969	0.53
629_R	633_S	0.969	0.53
156_V	526_L	0.968	0.53
603_I	613_R	0.967	0.53
107_C	359_A	0.967	0.53
320_F	326_Q	0.966	0.53
315_Q	320_F	0.963	0.53
71_R	135_P	0.963	0.53
490_L	523_I	0.963	0.53
76_L	591_R	0.960	0.53
394_I	498_V	0.960	0.53
300_L	305_V	0.960	0.53
107_C	125_A	0.959	0.53
596_S	610_M	0.956	0.52
318_R	338_V	0.955	0.52
79_A	132_I	0.952	0.52
128_T	156_V	0.950	0.52
25_L	170_L	0.949	0.52
155_E	163_G	0.947	0.52
316_R	323_L	0.946	0.52
355_D	525_A	0.946	0.52
324_Y	328_S	0.945	0.52
275_I	278_Q	0.944	0.52
66_S	124_L	0.943	0.51
614_G	620_L	0.943	0.51
87_G	90_L	0.941	0.51
45_E	155_E	0.940	0.51
317_L	326_Q	0.940	0.51
35_L	105_G	0.939	0.51
530_F	547_S	0.933	0.51
137_V	385_G	0.933	0.51
131_I	466_G	0.933	0.51
167_M	545_F	0.932	0.51
616_Q	624_L	0.930	0.50
265_W	277_E	0.930	0.50
24_A	28_T	0.929	0.50
235_R	248_Q	0.928	0.50
91_N	365_R	0.926	0.50
603_I	606_L	0.925	0.50
66_S	478_V	0.924	0.50
293_V	296_I	0.922	0.50
67_K	146_W	0.919	0.50
314_W	319_Y	0.919	0.50
394_I	499_G	0.915	0.49
24_A	449_A	0.915	0.49
401_A	485_D	0.914	0.49
451_M	468_L	0.910	0.49
606_L	613_R	0.908	0.49
620_L	628_Q	0.907	0.49
273_R	277_E	0.907	0.49
26_R	533_Q	0.905	0.49
598_V	603_I	0.905	0.49
449_A	582_V	0.904	0.48
123_Q	142_A	0.902	0.48
49_A	81_A	0.902	0.48
82_A	132_I	0.902	0.48
36_T	40_Y	0.900	0.48
387_N	474_S	0.900	0.48
318_R	323_L	0.900	0.48
43_L	59_P	0.895	0.48
123_Q	393_A	0.893	0.48
271_A	587_D	0.890	0.47
113_H	151_A	0.890	0.47
88_H	91_N	0.889	0.47
353_H	552_H	0.889	0.47
618_K	641_A	0.884	0.47
281_T	296_I	0.883	0.47
257_S	363_G	0.882	0.47
184_K	272_T	0.880	0.47
317_L	324_Y	0.878	0.46
335_Q	338_V	0.878	0.46
297_I	300_L	0.876	0.46
560_Q	564_A	0.876	0.46
279_L	317_L	0.875	0.46
499_G	529_D	0.874	0.46
266_P	288_T	0.873	0.46
323_L	337_G	0.869	0.46
320_F	323_L	0.869	0.46
411_L	414_R	0.866	0.46
26_R	148_I	0.866	0.46
131_I	396_C	0.865	0.45
100_M	490_L	0.865	0.45
313_F	317_L	0.863	0.45
34_A	179_L	0.863	0.45
114_F	122_F	0.863	0.45
620_L	634_L	0.860	0.45
158_V	162_C	0.859	0.45
146_W	437_L	0.858	0.45
62_G	74_G	0.857	0.45
401_A	442_L	0.856	0.45
210_H	230_S	0.856	0.45
82_A	133_A	0.855	0.45
81_A	467_Q	0.854	0.45
27_N	53_A	0.852	0.44
350_L	353_H	0.851	0.44
325_L	340_D	0.851	0.44
321_C	337_G	0.850	0.44
124_L	133_A	0.849	0.44
317_L	327_S	0.849	0.44
394_I	412_L	0.848	0.44
367_F	448_L	0.847	0.44
42_N	154_C	0.847	0.44
163_G	377_S	0.844	0.44
220_M	372_M	0.843	0.44
599_R	613_R	0.843	0.44
30_A	107_C	0.841	0.44
197_L	200_P	0.841	0.44
415_T	467_Q	0.838	0.43
169_I	279_L	0.838	0.43
359_A	363_G	0.838	0.43
67_K	78_G	0.837	0.43
435_S	548_L	0.837	0.43
107_C	126_G	0.836	0.43
29_I	55_V	0.833	0.43
72_I	161_L	0.833	0.43
322_R	326_Q	0.832	0.43
337_G	497_I	0.829	0.43
76_L	199_Q	0.828	0.43
100_M	361_W	0.828	0.43
108_T	112_A	0.827	0.43
87_G	154_C	0.826	0.42
509_I	586_R	0.824	0.42
304_N	308_Y	0.823	0.42
26_R	171_P	0.822	0.42
371_M	380_S	0.821	0.42
334_L	340_D	0.821	0.42
70_G	156_V	0.819	0.42
251_M	533_Q	0.818	0.42
400_S	412_L	0.818	0.42
316_R	322_R	0.817	0.42
408_S	471_F	0.817	0.42
609_V	612_E	0.815	0.42
49_A	76_L	0.814	0.42
224_R	545_F	0.813	0.41
384_A	491_N	0.812	0.41
620_L	631_C	0.811	0.41
91_N	117_N	0.811	0.41
538_P	586_R	0.810	0.41
115_T	551_H	0.810	0.41
317_L	322_R	0.809	0.41
155_E	437_L	0.809	0.41
326_Q	332_H	0.809	0.41
388_A	491_N	0.809	0.41
53_A	66_S	0.808	0.41
313_F	335_Q	0.808	0.41
315_Q	319_Y	0.807	0.41
282_A	293_V	0.807	0.41
37_V	398_L	0.806	0.41
395_S	471_F	0.804	0.41
233_R	506_A	0.801	0.41
221_N	249_L	0.801	0.41
120_Y	149_A	0.800	0.41
365_R	480_N	0.799	0.40
396_C	507_F	0.799	0.40
71_R	74_G	0.797	0.40
595_L	606_L	0.797	0.40
81_A	86_A	0.797	0.40
44_D	509_I	0.796	0.40
119_A	474_S	0.795	0.40
132_I	145_L	0.795	0.40
591_R	629_R	0.795	0.40
121_A	132_I	0.794	0.40
281_T	636_R	0.794	0.40
315_Q	334_L	0.791	0.40
56_V	134_F	0.790	0.40
198_W	202_T	0.790	0.40
261_M	581_V	0.789	0.40
616_Q	623_T	0.785	0.39
38_A	158_V	0.784	0.39
96_F	390_T	0.781	0.39
154_C	365_R	0.779	0.39
525_A	552_H	0.779	0.39
319_Y	330_E	0.778	0.39
619_S	634_L	0.778	0.39
190_L	198_W	0.775	0.39
66_S	116_N	0.774	0.39
179_L	194_A	0.773	0.39
53_A	127_Y	0.772	0.38
391_L	395_S	0.772	0.38
323_L	341_H	0.769	0.38
330_E	339_D	0.768	0.38
122_F	458_M	0.762	0.38
382_W	499_G	0.762	0.38
630_I	635_A	0.761	0.38
440_F	459_P	0.761	0.38
409_L	500_V	0.760	0.38
105_G	439_Q	0.759	0.37
315_Q	325_L	0.758	0.37
399_Y	499_G	0.758	0.37
55_V	71_R	0.757	0.37
608_G	625_E	0.755	0.37
366_T	592_S	0.753	0.37
260_R	577_N	0.748	0.37
437_L	440_F	0.747	0.37
66_S	70_G	0.747	0.37
299_P	311_V	0.745	0.36
368_C	421_L	0.745	0.36
47_Y	93_P	0.745	0.36
636_R	641_A	0.744	0.36
67_K	156_V	0.744	0.36
311_V	368_C	0.744	0.36
128_T	382_W	0.742	0.36
598_V	601_N	0.739	0.36
355_D	399_Y	0.739	0.36
281_T	292_T	0.737	0.36
326_Q	329_Q	0.737	0.36
67_K	521_R	0.736	0.36
131_I	453_L	0.735	0.36
183_L	239_A	0.735	0.36
101_S	105_G	0.734	0.36
133_A	395_S	0.733	0.36
622_A	626_E	0.732	0.36
293_V	297_I	0.730	0.35
624_L	627_L	0.729	0.35
85_L	286_S	0.728	0.35
184_K	335_Q	0.726	0.35
375_A	520_R	0.725	0.35
349_G	563_L	0.725	0.35
355_D	552_H	0.724	0.35
410_S	587_D	0.722	0.35
135_P	172_S	0.722	0.35
323_L	327_S	0.721	0.35
404_A	412_L	0.719	0.35
124_L	398_L	0.719	0.35
126_G	252_T	0.718	0.35
158_V	184_K	0.718	0.35
144_Q	367_F	0.718	0.35
397_V	400_S	0.718	0.35
313_F	321_C	0.716	0.34
316_R	327_S	0.716	0.34
111_C	117_N	0.713	0.34
621_A	625_E	0.712	0.34
317_L	325_L	0.712	0.34
21_W	30_A	0.710	0.34
96_F	133_A	0.710	0.34
273_R	281_T	0.708	0.34
461_F	465_W	0.708	0.34
312_A	319_Y	0.708	0.34
331_L	334_L	0.708	0.34
272_T	297_I	0.707	0.34
382_W	491_N	0.704	0.34
136_M	204_D	0.702	0.33
361_W	370_L	0.702	0.33
171_P	283_L	0.701	0.33
158_V	522_H	0.701	0.33
80_I	84_L	0.699	0.33
431_M	434_I	0.699	0.33
44_D	430_L	0.698	0.33
388_A	449_A	0.696	0.33
445_F	450_T	0.692	0.33
24_A	27_N	0.692	0.33
571_W	581_V	0.691	0.33
360_M	364_L	0.690	0.33
629_R	636_R	0.690	0.33
252_T	275_I	0.688	0.32
638_H	641_A	0.686	0.32
36_T	522_H	0.686	0.32
52_S	128_T	0.684	0.32
597_R	612_E	0.683	0.32
615_V	639_Q	0.683	0.32
251_M	522_H	0.683	0.32
317_L	331_L	0.680	0.32
300_L	532_D	0.678	0.32
95_F	604_S	0.678	0.32
23_Y	27_N	0.678	0.32
120_Y	126_G	0.677	0.32
295_R	421_L	0.677	0.32
76_L	119_A	0.674	0.32
89_T	531_V	0.673	0.31
150_Q	158_V	0.673	0.31
132_I	422_F	0.672	0.31
45_E	63_G	0.671	0.31
333_R	337_G	0.671	0.31
115_T	579_S	0.671	0.31
67_K	152_R	0.671	0.31
419_L	472_M	0.670	0.31
89_T	533_Q	0.670	0.31
27_N	63_G	0.669	0.31
289_D	498_V	0.669	0.31
36_T	549_T	0.668	0.31
358_E	436_D	0.667	0.31
425_V	490_L	0.667	0.31
135_P	229_W	0.666	0.31
156_V	426_V	0.665	0.31
127_Y	156_V	0.664	0.31
286_S	425_V	0.663	0.31
365_R	380_S	0.663	0.31
52_S	57_S	0.662	0.31
627_L	634_L	0.662	0.31
46_P	377_S	0.661	0.31
262_L	470_V	0.661	0.31
64_V	224_R	0.659	0.31
54_A	426_V	0.659	0.31
506_A	510_L	0.659	0.31
93_P	383_D	0.658	0.30
158_V	439_Q	0.657	0.30
576_L	586_R	0.656	0.30
254_V	276_L	0.656	0.30
104_L	233_R	0.656	0.30
316_R	325_L	0.655	0.30
598_V	606_L	0.651	0.30
45_E	400_S	0.650	0.30
616_Q	620_L	0.649	0.30
298_A	629_R	0.649	0.30
385_G	495_A	0.649	0.30
280_L	522_H	0.649	0.30
117_N	226_Q	0.648	0.30
329_Q	332_H	0.647	0.30
433_Q	488_D	0.646	0.30
435_S	438_W	0.646	0.30
548_L	552_H	0.644	0.30
91_N	182_A	0.644	0.30
75_S	128_T	0.644	0.30
257_S	392_A	0.644	0.30
328_S	338_V	0.643	0.30
621_A	632_D	0.641	0.29
241_L	376_W	0.639	0.29
71_R	119_A	0.639	0.29
42_N	470_V	0.639	0.29
57_S	225_I	0.638	0.29
23_Y	124_L	0.638	0.29
57_S	118_V	0.638	0.29
107_C	506_A	0.638	0.29
448_L	491_N	0.637	0.29
611_S	640_P	0.636	0.29
366_T	453_L	0.636	0.29
300_L	303_T	0.636	0.29
38_A	44_D	0.635	0.29
451_M	509_I	0.635	0.29
169_I	178_A	0.634	0.29
314_W	322_R	0.634	0.29
501_A	509_I	0.634	0.29
542_E	546_E	0.632	0.29
395_S	416_L	0.632	0.29
459_P	462_A	0.632	0.29
67_K	230_S	0.629	0.29
374_G	389_L	0.628	0.29
147_D	151_A	0.628	0.29
74_G	432_V	0.627	0.28
102_A	422_F	0.627	0.28
35_L	67_K	0.627	0.28
110_A	363_G	0.626	0.28
29_I	449_A	0.625	0.28
92_E	175_D	0.625	0.28
49_A	93_P	0.625	0.28
409_L	507_F	0.625	0.28
508_A	534_L	0.624	0.28
346_R	350_L	0.624	0.28
399_Y	406_F	0.624	0.28
599_R	610_M	0.623	0.28
398_L	415_T	0.622	0.28
67_K	491_N	0.622	0.28
52_S	67_K	0.621	0.28
52_S	70_G	0.621	0.28
111_C	156_V	0.620	0.28
591_R	624_L	0.619	0.28
106_F	137_V	0.619	0.28
422_F	447_L	0.619	0.28
58_F	107_C	0.619	0.28
441_L	509_I	0.619	0.28
292_T	301_R	0.618	0.28
376_W	380_S	0.618	0.28
114_F	118_V	0.618	0.28
430_L	487_A	0.618	0.28
107_C	365_R	0.617	0.28
25_L	335_Q	0.617	0.28
181_T	343_R	0.617	0.28
220_M	416_L	0.616	0.28
285_S	296_I	0.616	0.28
406_F	522_H	0.615	0.28
42_N	167_M	0.615	0.28
115_T	220_M	0.615	0.28
619_S	624_L	0.615	0.28
68_S	231_H	0.614	0.28
161_L	272_T	0.614	0.28
615_V	627_L	0.612	0.28
604_S	614_G	0.612	0.28
230_S	257_S	0.611	0.27
126_G	130_A	0.611	0.27
252_T	548_L	0.611	0.27
248_Q	583_W	0.611	0.27
227_A	256_S	0.610	0.27
48_W	453_L	0.609	0.27
622_A	625_E	0.607	0.27
184_K	338_V	0.607	0.27
623_T	626_E	0.607	0.27
615_V	618_K	0.606	0.27
571_W	574_V	0.606	0.27
89_T	458_M	0.604	0.27
83_L	153_V	0.602	0.27
81_A	99_S	0.602	0.27
112_A	513_G	0.602	0.27
125_A	472_M	0.601	0.27
589_E	603_I	0.601	0.27
53_A	58_F	0.601	0.27
421_L	541_S	0.601	0.27
33_L	166_M	0.600	0.27
181_T	274_E	0.600	0.27
82_A	153_V	0.599	0.27
223_L	477_A	0.599	0.27
594_P	597_R	0.599	0.27
591_R	639_Q	0.598	0.27
289_D	311_V	0.597	0.27
621_A	624_L	0.596	0.27
390_T	419_L	0.595	0.27
449_A	452_Q	0.595	0.27
280_L	374_G	0.593	0.26
92_E	165_M	0.593	0.26
131_I	145_L	0.593	0.26
612_E	616_Q	0.592	0.26
111_C	267_S	0.592	0.26
99_S	105_G	0.591	0.26
112_A	154_C	0.591	0.26
331_L	338_V	0.591	0.26
132_I	496_K	0.589	0.26
421_L	482_P	0.588	0.26
103_W	162_C	0.587	0.26
111_C	239_A	0.586	0.26
35_L	365_R	0.586	0.26
208_A	283_L	0.585	0.26
380_S	409_L	0.585	0.26
316_R	339_D	0.583	0.26
328_S	331_L	0.583	0.26
65_I	424_F	0.582	0.26
187_H	494_L	0.582	0.26
271_A	283_L	0.580	0.26
112_A	512_P	0.580	0.26
46_P	62_G	0.580	0.26
186_M	392_A	0.579	0.26
56_V	382_W	0.579	0.26
258_L	456_L	0.579	0.26
39_Y	480_N	0.579	0.26
82_A	346_R	0.578	0.25
109_W	415_T	0.578	0.25
281_T	601_N	0.577	0.25
217_I	465_W	0.577	0.25
288_T	425_V	0.577	0.25
474_S	496_K	0.576	0.25
65_I	70_G	0.576	0.25
365_R	415_T	0.575	0.25
278_Q	528_R	0.574	0.25
165_M	538_P	0.572	0.25
157_I	528_R	0.572	0.25
252_T	487_A	0.571	0.25
158_V	362_S	0.570	0.25
328_S	333_R	0.570	0.25
167_M	457_Q	0.570	0.25
198_W	523_I	0.570	0.25
113_H	506_A	0.569	0.25
217_I	330_E	0.569	0.25
87_G	93_P	0.569	0.25
598_V	609_V	0.568	0.25
241_L	510_L	0.568	0.25
113_H	359_A	0.568	0.25
530_F	552_H	0.568	0.25
22_R	449_A	0.568	0.25
302_P	310_H	0.568	0.25
627_L	635_A	0.568	0.25
290_V	296_I	0.567	0.25
54_A	469_I	0.567	0.25
527_R	530_F	0.567	0.25
597_R	630_I	0.566	0.25
243_A	247_Q	0.566	0.25
335_Q	339_D	0.566	0.25
616_Q	622_A	0.566	0.25
343_R	347_T	0.564	0.25
59_P	67_K	0.564	0.25
420_S	495_A	0.564	0.25
393_A	514_S	0.564	0.25
43_L	398_L	0.564	0.25
126_G	506_A	0.563	0.25
20_Q	510_L	0.563	0.25
365_R	389_L	0.562	0.25
31_M	42_N	0.562	0.25
360_M	363_G	0.562	0.25
333_R	371_M	0.562	0.25
599_R	602_C	0.562	0.25
256_S	577_N	0.562	0.25
609_V	614_G	0.561	0.25
413_M	495_A	0.560	0.24
22_R	380_S	0.560	0.24
300_L	503_A	0.559	0.24
47_Y	253_S	0.557	0.24
630_I	645_L	0.557	0.24
71_R	432_V	0.557	0.24
559_S	563_L	0.556	0.24
55_V	440_F	0.555	0.24
127_Y	353_H	0.555	0.24
73_A	82_A	0.554	0.24
288_T	305_V	0.553	0.24
305_V	310_H	0.553	0.24
65_I	75_S	0.552	0.24
158_V	545_F	0.552	0.24
42_N	378_I	0.551	0.24
119_A	416_L	0.550	0.24
504_W	508_A	0.550	0.24
615_V	635_A	0.549	0.24
283_L	396_C	0.548	0.24
608_G	612_E	0.548	0.24
147_D	353_H	0.547	0.24
227_A	426_V	0.546	0.24
366_T	502_L	0.546	0.24
235_R	241_L	0.546	0.24
77_L	622_A	0.545	0.24
298_A	302_P	0.544	0.24
621_A	629_R	0.543	0.23
120_Y	159_G	0.542	0.23
37_V	233_R	0.542	0.23
300_L	633_S	0.542	0.23
73_A	170_L	0.541	0.23
42_N	480_N	0.541	0.23
63_G	210_H	0.541	0.23
159_G	165_M	0.540	0.23
123_Q	397_V	0.540	0.23
252_T	380_S	0.539	0.23
349_G	522_H	0.538	0.23
325_L	338_V	0.538	0.23
74_G	120_Y	0.537	0.23
111_C	518_K	0.537	0.23
158_V	553_V	0.537	0.23
20_Q	453_L	0.536	0.23
93_P	226_Q	0.536	0.23
39_Y	131_I	0.536	0.23
214_I	253_S	0.536	0.23
125_A	495_A	0.536	0.23
57_S	223_L	0.535	0.23
480_N	484_Y	0.535	0.23
426_V	519_S	0.534	0.23
172_S	244_L	0.532	0.23
64_V	473_G	0.532	0.23
70_G	117_N	0.530	0.23
208_A	413_M	0.530	0.23
625_E	628_Q	0.530	0.23
284_A	413_M	0.529	0.23
618_K	636_R	0.528	0.23
113_H	356_N	0.527	0.23
300_L	505_L	0.527	0.23
38_A	544_E	0.527	0.23
107_C	404_A	0.526	0.23
194_A	255_I	0.525	0.22
390_T	428_F	0.525	0.22
333_R	340_D	0.524	0.22
22_R	171_P	0.524	0.22
271_A	281_T	0.523	0.22
224_R	546_E	0.523	0.22
271_A	274_E	0.522	0.22
319_Y	337_G	0.520	0.22
38_A	48_W	0.519	0.22
101_S	370_L	0.519	0.22
36_T	217_I	0.519	0.22
38_A	151_A	0.519	0.22
376_W	437_L	0.519	0.22
608_G	617_Q	0.519	0.22
52_S	382_W	0.518	0.22
123_Q	127_Y	0.518	0.22
87_G	114_F	0.517	0.22
339_D	344_L	0.517	0.22
610_M	615_V	0.517	0.22
327_S	332_H	0.517	0.22
362_S	366_T	0.516	0.22
66_S	135_P	0.516	0.22
328_S	436_D	0.515	0.22
54_A	117_N	0.515	0.22
59_P	152_R	0.515	0.22
288_T	291_Y	0.514	0.22
115_T	377_S	0.514	0.22
323_L	363_G	0.513	0.22
87_G	440_F	0.513	0.22
619_S	625_E	0.512	0.22
39_Y	146_W	0.511	0.22
369_T	412_L	0.510	0.22
284_A	288_T	0.510	0.22
158_V	463_A	0.509	0.22
123_Q	507_F	0.509	0.22
364_L	405_P	0.509	0.22
306_A	310_H	0.509	0.22
297_I	311_V	0.508	0.22
245_L	253_S	0.508	0.22
91_N	166_M	0.508	0.22
86_A	451_M	0.507	0.22
123_Q	530_F	0.506	0.21
119_A	392_A	0.506	0.21
131_I	448_L	0.506	0.21
226_Q	229_W	0.506	0.21
43_L	503_A	0.505	0.21
301_R	310_H	0.505	0.21
615_V	637_H	0.504	0.21
186_M	465_W	0.503	0.21
595_L	613_R	0.503	0.21
125_A	408_S	0.503	0.21
360_M	636_R	0.503	0.21
599_R	606_L	0.503	0.21
131_I	490_L	0.503	0.21
115_T	135_P	0.502	0.21
116_N	365_R	0.502	0.21
99_S	131_I	0.501	0.21
548_L	551_H	0.501	0.21
110_A	145_L	0.500	0.21

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zz9A	3	0.2388	37.2	0.977	Contact Map
3iyzA	3	0.2388	26	0.979	Contact Map
4k0jA	3	0.2343	20.9	0.98	Contact Map
3llqA	3	0.2821	19.9	0.98	Contact Map
3d9sA	3	0.306	17.6	0.981	Contact Map
1j4nA	4	0.309	16.9	0.981	Contact Map
3effK	4	0.197	16	0.981	Contact Map
4dx5A	3	0.2612	15.5	0.981	Contact Map
2b6oA	6	0.2925	15.4	0.981	Contact Map
3cn5A	3	0.2403	15.1	0.981	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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