GREMLIN Database
YDHJ - Uncharacterized protein YdhJ
UniProt: P76185 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13944
Length: 285 (261)
Sequences: 30013 (24201)
Seq/√Len: 1498.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_E74_T3.2441.00
71_L153_E3.1301.00
67_N159_S2.7781.00
59_N74_T2.4761.00
74_T153_E2.4681.00
41_R191_I2.4461.00
108_R116_I2.3361.00
207_P220_Q2.3201.00
50_Q151_Q2.3011.00
77_K81_Q2.2471.00
65_L161_W2.2091.00
108_R124_A2.1921.00
71_L155_R2.1821.00
67_N70_D2.1671.00
59_N71_L2.0331.00
192_G260_V2.0281.00
163_T183_V2.0071.00
209_Q220_Q2.0021.00
128_V132_Q1.9121.00
209_Q218_T1.8821.00
109_R112_S1.8471.00
68_A159_S1.8161.00
125_N129_K1.8071.00
88_Q146_Q1.7851.00
105_A109_R1.7481.00
136_D139_Q1.7431.00
191_I240_S1.7421.00
85_L88_Q1.7131.00
102_N106_N1.7081.00
118_A122_D1.7011.00
120_E123_T1.6861.00
46_S178_P1.6821.00
174_D177_K1.6661.00
92_A95_Q1.6601.00
105_A121_L1.6421.00
217_K251_W1.6281.00
129_K132_Q1.6231.00
109_R125_N1.6091.00
61_K64_Q1.6061.00
40_I190_V1.5811.00
135_V139_Q1.5651.00
84_E88_Q1.5361.00
84_E146_Q1.5311.00
207_P222_H1.5281.00
81_Q85_L1.5191.00
143_K146_Q1.4961.00
43_E184_D1.4921.00
55_I73_L1.4841.00
144_Q148_Q1.4721.00
23_W27_N1.4711.00
23_W26_W1.4681.00
190_V258_V1.4481.00
71_L74_T1.4401.00
91_L95_Q1.4371.00
81_Q149_L1.4331.00
121_L125_N1.4301.00
56_V76_D1.4031.00
80_F152_T1.4011.00
55_I167_T1.3931.00
86_N141_T1.3841.00
105_A125_N1.3831.00
195_E198_K1.3821.00
224_S242_I1.3771.00
53_G75_I1.3721.00
44_Q181_A1.3711.00
209_Q263_A1.3711.00
99_A103_N1.3681.00
46_S181_A1.3671.00
184_D187_S1.3551.00
52_S175_T1.3541.00
56_V74_T1.3481.00
142_L146_Q1.3431.00
65_L185_S1.3371.00
98_L102_N1.3331.00
35_T261_R1.3321.00
95_Q139_Q1.3251.00
100_K104_E1.3231.00
73_L154_I1.3151.00
93_K134_S1.3141.00
119_E123_T1.3141.00
93_K97_D1.3011.00
224_S244_D1.2901.00
60_I70_D1.2881.00
106_N109_R1.2801.00
88_Q142_L1.2791.00
83_A148_Q1.2771.00
212_L258_V1.2771.00
127_N130_A1.2731.00
134_S137_A1.2631.00
164_N181_A1.2591.00
91_L142_L1.2501.00
147_W151_Q1.2491.00
35_T259_P1.2491.00
162_V180_F1.2491.00
22_G26_W1.2471.00
99_A102_N1.2411.00
83_A86_N1.2351.00
104_E123_T1.2321.00
139_Q143_K1.2251.00
88_Q92_A1.2241.00
57_E169_I1.2231.00
109_R121_L1.2171.00
106_N110_H1.2171.00
102_N128_V1.2121.00
102_N132_Q1.2071.00
211_T218_T1.2061.00
83_A144_Q1.2021.00
211_T261_R1.2001.00
95_Q135_V1.1981.00
189_Y242_I1.1961.00
86_N90_Q1.1941.00
165_L168_R1.1921.00
90_Q93_K1.1911.00
98_L128_V1.1901.00
107_R122_D1.1841.00
72_L180_F1.1811.00
61_K165_L1.1791.00
209_Q261_R1.1741.00
84_E142_L1.1701.00
50_Q54_R1.1561.00
77_K152_T1.1521.00
110_H113_Q1.1391.00
231_Y234_S1.1261.00
221_G243_P1.1231.00
20_L24_W1.1081.00
98_L132_Q1.1041.00
95_Q99_A1.1031.00
45_V158_V1.1021.00
62_D164_N1.0991.00
123_T127_N1.0981.00
105_A128_V1.0971.00
91_L139_Q1.0941.00
137_A141_T1.0921.00
49_P154_I1.0821.00
40_I188_F1.0801.00
127_N131_M1.0801.00
222_H244_D1.0711.00
77_K153_E1.0651.00
97_D100_K1.0631.00
203_R206_A1.0601.00
187_S244_D1.0521.00
190_V210_I1.0511.00
104_E108_R1.0511.00
21_A25_L1.0451.00
73_L180_F1.0451.00
90_Q141_T1.0441.00
247_P250_P1.0431.00
94_A97_D1.0411.00
122_D125_N1.0331.00
156_A182_L1.0331.00
100_K103_N1.0311.00
90_Q94_A1.0251.00
97_D134_S1.0211.00
210_I221_G1.0161.00
91_L135_V1.0131.00
138_A141_T1.0121.00
65_L159_S1.0091.00
146_Q150_A0.9971.00
60_I180_F0.9931.00
160_G182_L0.9921.00
85_L143_K0.9901.00
132_Q136_D0.9901.00
141_T144_Q0.9881.00
230_I239_S0.9881.00
52_S174_D0.9851.00
73_L179_L0.9731.00
173_A179_L0.9721.00
267_V270_D0.9611.00
94_A138_A0.9571.00
190_V260_V0.9561.00
98_L135_V0.9541.00
54_R172_Y0.9511.00
192_G241_L0.9501.00
104_E119_E0.9461.00
40_I252_V0.9421.00
108_R120_E0.9401.00
227_G240_S0.9381.00
97_D130_A0.9351.00
193_Y238_D0.9341.00
19_V23_W0.9331.00
79_P83_A0.9321.00
38_G258_V0.9271.00
74_T77_K0.9251.00
58_L73_L0.9251.00
84_E149_L0.9251.00
58_L169_I0.9191.00
166_T181_A0.9111.00
55_I173_A0.9051.00
145_A148_Q0.8971.00
211_T259_P0.8941.00
26_W29_Y0.8891.00
60_I165_L0.8871.00
198_K201_H0.8831.00
166_T178_P0.8821.00
101_A131_M0.8741.00
165_L180_F0.8731.00
26_W30_M0.8691.00
156_A159_S0.8681.00
49_P73_L0.8651.00
111_L114_N0.8641.00
64_Q70_D0.8621.00
95_Q98_L0.8621.00
36_R192_G0.8571.00
189_Y224_S0.8561.00
87_A138_A0.8531.00
114_N118_A0.8531.00
73_L165_L0.8481.00
56_V59_N0.8481.00
47_I157_P0.8411.00
40_I258_V0.8401.00
99_A129_K0.8351.00
51_V80_F0.8331.00
50_Q79_P0.8291.00
194_F202_I0.8291.00
125_N128_V0.8271.00
134_S138_A0.8251.00
130_A134_S0.8251.00
62_D165_L0.8231.00
103_N122_D0.8201.00
78_T147_W0.8191.00
192_G243_P0.8151.00
147_W150_A0.8141.00
49_P173_A0.8131.00
253_R256_Q0.8021.00
60_I162_V0.8001.00
22_G25_L0.7971.00
56_V77_K0.7961.00
158_V182_L0.7941.00
92_A136_D0.7931.00
42_A254_L0.7921.00
208_A243_P0.7901.00
87_A90_Q0.7851.00
43_E168_R0.7831.00
140_A143_K0.7821.00
208_A221_G0.7801.00
116_I120_E0.7791.00
210_I243_P0.7781.00
65_L250_P0.7771.00
263_A266_K0.7761.00
103_N106_N0.7701.00
138_A142_L0.7691.00
100_K126_L0.7651.00
90_Q137_A0.7611.00
223_V241_L0.7581.00
211_T216_N0.7551.00
97_D101_A0.7521.00
100_K123_T0.7511.00
52_S172_Y0.7501.00
161_W185_S0.7441.00
192_G262_F0.7421.00
44_Q183_V0.7391.00
143_K147_W0.7281.00
82_I147_W0.7261.00
136_D140_A0.7261.00
111_L115_F0.7231.00
36_R194_F0.7231.00
188_F254_L0.7231.00
225_S242_I0.7191.00
46_S171_D0.7151.00
82_I140_A0.7131.00
221_G241_L0.7131.00
45_V157_P0.7121.00
66_V72_L0.7081.00
144_Q147_W0.7051.00
21_A24_W0.7051.00
68_A157_P0.6891.00
54_R76_D0.6871.00
25_L28_Y0.6851.00
90_Q134_S0.6851.00
210_I260_V0.6841.00
108_R119_E0.6831.00
207_P263_A0.6801.00
199_L237_S0.6791.00
87_A145_A0.6781.00
60_I64_Q0.6781.00
49_P179_L0.6691.00
41_R189_Y0.6691.00
18_A21_A0.6691.00
83_A87_A0.6681.00
168_R171_D0.6681.00
77_K149_L0.6681.00
117_S120_E0.6651.00
193_Y231_Y0.6631.00
89_A140_A0.6621.00
239_S242_I0.6621.00
178_P181_A0.6611.00
88_Q91_L0.6611.00
24_W28_Y0.6611.00
124_A127_N0.6591.00
107_R111_L0.6591.00
191_I238_D0.6591.00
47_I180_F0.6571.00
139_Q142_L0.6541.00
25_L29_Y0.6541.00
30_M33_P0.6531.00
94_A131_M0.6511.00
192_G208_A0.6501.00
111_L117_S0.6471.00
183_V254_L0.6461.00
20_L26_W0.6451.00
131_M135_V0.6411.00
213_Y259_P0.6411.00
189_Y240_S0.6411.00
104_E107_R0.6361.00
225_S240_S0.6361.00
87_A91_L0.6361.00
116_I121_L0.6281.00
79_P148_Q0.6251.00
204_E224_S0.6251.00
39_K235_V0.6241.00
150_A155_R0.6231.00
129_K133_A0.6221.00
84_E87_A0.6201.00
94_A98_L0.6171.00
150_A153_E0.6151.00
205_G222_H0.6121.00
20_L23_W0.6121.00
24_W27_N0.6121.00
120_E124_A0.6111.00
118_A125_N0.6101.00
48_T178_P0.6091.00
89_A92_A0.6091.00
49_P52_S0.6061.00
21_A26_W0.6061.00
118_A121_L0.6031.00
148_Q151_Q0.6021.00
12_I16_V0.5991.00
114_N117_S0.5981.00
43_E169_I0.5981.00
191_I242_I0.5971.00
208_A241_L0.5941.00
14_V17_V0.5941.00
36_R262_F0.5911.00
193_Y240_S0.5881.00
204_E226_I0.5881.00
36_R260_V0.5871.00
81_Q84_E0.5851.00
167_T171_D0.5831.00
240_S244_D0.5831.00
16_V20_L0.5821.00
119_E122_D0.5811.00
58_L165_L0.5801.00
83_A145_A0.5801.00
36_R198_K0.5791.00
97_D127_N0.5751.00
210_I258_V0.5741.00
230_I237_S0.5691.00
171_D177_K0.5681.00
202_I223_V0.5641.00
92_A96_S0.5621.00
84_E145_A0.5611.00
48_T177_K0.5571.00
107_R119_E0.5571.00
131_M134_S0.5571.00
96_S100_K0.5561.00
215_D219_L0.5531.00
141_T145_A0.5521.00
235_V238_D0.5511.00
78_T81_Q0.5501.00
126_L130_A0.5501.00
128_V131_M0.5491.00
59_N70_D0.5481.00
27_N30_M0.5461.00
108_R111_L0.5401.00
104_E124_A0.5401.00
80_F145_A0.5391.00
48_T172_Y0.5391.00
19_V26_W0.5371.00
187_S242_I0.5361.00
86_N144_Q0.5361.00
212_L252_V0.5321.00
196_E257_R0.5311.00
115_F119_E0.5301.00
167_T179_L0.5271.00
181_A229_A0.5271.00
163_T228_R0.5271.00
51_V152_T0.5251.00
63_N225_S0.5221.00
104_E127_N0.5221.00
45_V182_L0.5211.00
158_V184_D0.5181.00
49_P75_I0.5151.00
87_A142_L0.5121.00
214_S256_Q0.5111.00
167_T177_K0.5101.00
78_T150_A0.5101.00
28_Y31_Q0.5091.00
42_A183_V0.5071.00
205_G223_V0.5041.00
82_I85_L0.5021.00
164_N178_P0.5001.00
228_R253_R0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2f1mA 2 0.807 100 0.312 Contact Map
3fppA 3 0.8667 100 0.332 Contact Map
4dk0A 5 0.9263 100 0.341 Contact Map
3lnnA 6 0.9439 100 0.342 Contact Map
4tkoB 1 0.8105 100 0.35 Contact Map
1vf7A 5 0.7825 100 0.377 Contact Map
3ne5B 3 0.8105 100 0.378 Contact Map
4l8jA 2 0.8947 100 0.384 Contact Map
4kkuA 1 0.6351 100 0.456 Contact Map
2k32A 1 0.4 99.8 0.644 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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