GREMLIN Database
RSXD - Electron transport complex subunit RsxD
UniProt: P76182 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13936
Length: 352 (308)
Sequences: 1941 (1213)
Seq/√Len: 69.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
109_A126_I3.9481.00
57_A103_V3.9161.00
23_L233_W3.6041.00
306_L331_A3.5071.00
57_A107_I3.4101.00
244_I287_L3.3461.00
252_L279_T3.2601.00
247_S304_G3.2191.00
53_S99_V3.2161.00
32_I47_I3.1161.00
34_A226_A3.0881.00
50_A98_V2.8571.00
251_T305_A2.8491.00
101_G131_L2.6881.00
46_Q98_V2.6311.00
23_L237_Q2.5881.00
103_V107_I2.4791.00
303_F307_A2.3221.00
51_S79_L2.2991.00
104_F108_I2.2711.00
282_G324_V2.2081.00
54_A102_T2.1841.00
22_L76_N2.1701.00
95_W99_V2.1681.00
104_F130_V2.1271.00
104_F126_I2.0961.00
84_L281_L2.0551.00
231_G284_F2.0341.00
78_A106_V2.0311.00
49_L95_W2.0261.00
255_C309_L1.9941.00
85_L127_G1.9841.00
93_A97_M1.9651.00
296_T299_G1.9581.00
248_F307_A1.9571.00
34_A38_F1.9461.00
53_S57_A1.9371.00
25_L83_L1.9031.00
46_Q93_A1.8991.00
252_L312_W1.8981.00
311_V324_V1.8791.00
248_F324_V1.8721.00
35_Q219_G1.8501.00
253_A270_P1.8161.00
32_I87_V1.8011.00
243_H297_N1.7731.00
299_G338_I1.7431.00
211_Y225_L1.7431.00
242_W246_L1.7431.00
248_F311_V1.7381.00
235_L284_F1.7371.00
233_W237_Q1.7241.00
251_T255_C1.7231.00
133_I326_F1.7191.00
121_F333_I1.7151.00
48_L52_V1.7031.00
76_N79_L1.6861.00
210_I276_S1.6811.00
255_C312_W1.6801.00
212_S225_L1.6781.00
55_L73_L1.6720.99
213_G221_Q1.6710.99
25_L79_L1.6580.99
22_L26_L1.6410.99
23_L239_A1.6210.99
55_L79_L1.6160.99
62_L69_V1.5740.99
116_L291_V1.5640.99
244_I293_A1.5530.99
302_I338_I1.5480.99
49_L99_V1.5200.99
53_S102_T1.5080.99
32_I83_L1.4970.99
309_L313_L1.4960.99
224_N280_M1.4710.99
25_L76_N1.4560.99
47_I87_V1.4530.99
206_M209_P1.4450.98
263_S266_T1.4430.98
259_G312_W1.4430.98
88_S325_A1.4380.98
31_G227_W1.4370.98
213_G217_G1.4330.98
208_Y212_S1.4180.98
302_I342_T1.4140.98
91_P143_L1.4060.98
256_A312_W1.3890.98
225_L229_A1.3760.98
97_M138_Q1.3740.98
249_L274_L1.3720.98
18_S22_L1.3540.98
301_L305_A1.3510.98
89_I98_V1.3380.97
247_S301_L1.3360.97
33_A37_W1.3330.97
313_L317_F1.3280.97
232_V236_W1.3280.97
251_T309_L1.3230.97
23_L26_L1.3210.97
98_V102_T1.3070.97
29_V33_A1.3040.97
287_L307_A1.3020.97
241_R300_R1.2990.97
227_W284_F1.2980.97
93_A98_V1.2900.97
85_L101_G1.2800.97
82_G86_A1.2730.97
201_S204_Q1.2660.96
61_V107_I1.2650.96
303_F306_L1.2490.96
304_G308_G1.2410.96
47_I83_L1.2390.96
228_L232_V1.2380.96
27_A233_W1.2370.96
227_W281_L1.2230.96
229_A233_W1.2150.96
253_A274_L1.2150.96
217_G221_Q1.1860.95
129_V133_I1.1780.95
59_A69_V1.1680.94
54_A82_G1.1520.94
28_A83_L1.1470.94
248_F283_A1.1460.94
28_A281_L1.1440.94
57_A102_T1.1420.94
85_L89_I1.1410.94
257_M270_P1.1390.94
263_S267_L1.1260.93
320_Y326_F1.1240.93
210_I275_L1.1230.93
105_A127_G1.1130.93
344_P348_G1.1100.93
77_S116_L1.1090.93
287_L308_G1.1070.93
109_A127_G1.0870.92
314_I320_Y1.0870.92
227_W280_M1.0850.92
56_L59_A1.0600.91
247_S251_T1.0580.91
50_A102_T1.0500.91
32_I36_L1.0320.90
131_L139_M1.0320.90
260_W270_P1.0270.90
231_G245_P1.0120.89
25_L80_L1.0050.89
256_A273_H1.0040.89
53_S103_V1.0030.89
287_L304_G1.0030.89
30_P230_G0.9990.88
250_V253_A0.9880.88
257_M261_L0.9860.88
231_G235_L0.9610.86
249_L283_A0.9590.86
338_I342_T0.9560.86
121_F126_I0.9530.86
245_P284_F0.9520.86
260_W269_A0.9500.86
209_P214_I0.9430.85
85_L131_L0.9410.85
27_A285_F0.9390.85
207_Q275_L0.9370.85
35_Q227_W0.9340.85
127_G231_G0.9300.84
207_Q269_A0.9290.84
59_A62_L0.9280.84
45_V95_W0.9270.84
42_G91_P0.9250.84
181_D187_T0.9230.84
47_I86_A0.9210.84
248_F287_L0.9120.83
31_G230_G0.9110.83
232_V235_L0.9070.83
239_A290_P0.9040.83
106_V111_Q0.9030.83
243_H300_R0.9020.83
76_N80_L0.8990.82
85_L102_T0.8960.82
301_L304_G0.8960.82
257_M260_W0.8900.82
92_L143_L0.8840.81
22_L25_L0.8840.81
42_G95_W0.8830.81
211_Y228_L0.8830.81
61_V65_R0.8800.81
314_I323_G0.8790.81
25_L29_V0.8760.81
78_A82_G0.8760.81
247_S250_V0.8710.80
125_M286_I0.8700.80
244_I304_G0.8690.80
89_I93_A0.8680.80
268_A272_I0.8660.80
61_V112_L0.8650.80
125_M328_V0.8590.79
35_Q220_W0.8560.79
29_V32_I0.8530.79
129_V326_F0.8480.79
286_I328_V0.8440.78
258_L262_F0.8360.78
21_M24_V0.8310.77
213_G220_W0.8310.77
297_N300_R0.8300.77
207_Q272_I0.8300.77
49_L98_V0.8290.77
33_A36_L0.8280.77
260_W264_P0.8280.77
273_H316_S0.8270.77
228_L280_M0.8260.77
210_I215_L0.8240.77
119_N122_N0.8240.77
306_L334_T0.8200.76
75_D116_L0.8170.76
39_F222_W0.8140.76
31_G226_A0.8090.75
34_A222_W0.8080.75
201_S265_E0.8070.75
57_A99_V0.8050.75
345_R349_H0.8040.75
129_V329_L0.7990.74
19_R22_L0.7960.74
247_S305_A0.7920.74
128_Y286_I0.7920.74
128_Y322_D0.7910.74
248_F251_T0.7890.73
221_Q322_D0.7870.73
120_P333_I0.7870.73
232_V254_L0.7840.73
250_V301_L0.7840.73
17_T20_I0.7810.73
35_Q43_T0.7780.72
294_S335_V0.7780.72
63_K66_K0.7760.72
88_S278_A0.7760.72
306_L330_L0.7750.72
88_S286_I0.7690.71
51_S82_G0.7680.71
61_V64_L0.7620.71
15_R19_R0.7540.70
34_A214_I0.7520.70
231_G280_M0.7490.69
312_W316_S0.7460.69
88_S125_M0.7450.69
259_G263_S0.7430.69
50_A89_I0.7430.69
280_M284_F0.7410.69
314_I321_P0.7390.68
185_Q188_P0.7380.68
38_F222_W0.7380.68
42_G46_Q0.7370.68
245_P283_A0.7360.68
35_Q87_V0.7330.68
49_L52_V0.7310.68
65_R111_Q0.7290.67
89_I101_G0.7280.67
59_A63_K0.7250.67
259_G316_S0.7230.67
72_T111_Q0.7230.67
49_L53_S0.7210.67
192_F195_S0.7200.66
224_N231_G0.7160.66
307_A324_V0.7120.66
249_L280_M0.7110.65
42_G45_V0.7110.65
55_L82_G0.7110.65
249_L284_F0.7090.65
186_A189_L0.7050.65
55_L59_A0.7050.65
19_R23_L0.7020.64
132_L324_V0.7020.64
306_L310_L0.7010.64
224_N275_L0.7010.64
192_F268_A0.6990.64
125_M325_A0.6950.64
215_L275_L0.6950.64
191_T205_I0.6940.64
27_A30_P0.6940.64
62_L111_Q0.6920.63
31_G281_L0.6860.63
279_T324_V0.6850.63
218_A322_D0.6840.62
246_L250_V0.6820.62
249_L252_L0.6800.62
32_I35_Q0.6740.61
126_I130_V0.6740.61
302_I327_A0.6740.61
323_G327_A0.6720.61
118_Q127_G0.6700.61
36_L43_T0.6690.61
60_L63_K0.6690.61
137_V140_T0.6680.61
293_A303_F0.6670.61
14_Q19_R0.6630.60
224_N227_W0.6620.60
46_Q86_A0.6610.60
21_M119_N0.6590.60
226_A230_G0.6550.59
47_I82_G0.6520.59
256_A316_S0.6520.59
89_I131_L0.6490.58
81_T289_D0.6480.58
226_A229_A0.6460.58
233_W236_W0.6450.58
38_F214_I0.6450.58
109_A112_L0.6440.58
104_F127_G0.6420.58
60_L103_V0.6420.58
83_L86_A0.6410.57
57_A60_L0.6410.57
128_Y221_Q0.6400.57
337_L341_Y0.6350.57
109_A121_F0.6350.57
304_G312_W0.6300.56
257_M264_P0.6240.55
296_T338_I0.6230.55
32_I44_L0.6220.55
47_I51_S0.6220.55
230_G284_F0.6210.55
18_S76_N0.6190.55
282_G328_V0.6190.55
262_F266_T0.6180.55
184_S187_T0.6170.55
18_S74_K0.6170.55
181_D186_A0.6150.54
40_G44_L0.6130.54
111_Q120_P0.6120.54
226_A235_L0.6090.54
130_V323_G0.6090.54
46_Q219_G0.6080.54
259_G317_F0.6070.53
27_A230_G0.6070.53
129_V325_A0.6060.53
54_A57_A0.6060.53
254_L258_L0.6050.53
97_M139_M0.6030.53
224_N228_L0.6030.53
31_G284_F0.6030.53
31_G87_V0.6010.53
330_L334_T0.6010.53
296_T335_V0.6010.53
207_Q271_Q0.6010.53
24_V77_S0.5970.52
20_I290_P0.5970.52
232_V284_F0.5960.52
307_A331_A0.5960.52
76_N86_A0.5950.52
89_I276_S0.5950.52
58_E110_K0.5950.52
130_V133_I0.5920.52
62_L72_T0.5900.51
217_G220_W0.5900.51
24_V286_I0.5900.51
292_T334_T0.5890.51
303_F334_T0.5890.51
286_I325_A0.5880.51
235_L300_R0.5880.51
183_I208_Y0.5870.51
298_R342_T0.5870.51
76_N116_L0.5860.51
13_N180_I0.5840.51
249_L279_T0.5810.50
220_W227_W0.5800.50
262_F267_L0.5790.50
88_S139_M0.5790.50
108_I126_I0.5760.50
208_Y225_L0.5740.49
278_A324_V0.5740.49
310_L327_A0.5740.49
252_L283_A0.5730.49
211_Y223_V0.5730.49
191_T196_V0.5730.49
147_E309_L0.5720.49
272_I276_S0.5720.49
346_V349_H0.5700.49
13_N37_W0.5700.49
211_Y275_L0.5690.49
252_L284_F0.5680.49
97_M100_L0.5680.49
128_Y220_W0.5660.48
310_L331_A0.5660.48
139_M230_G0.5650.48
139_M244_I0.5650.48
253_A271_Q0.5630.48
344_P347_Y0.5620.48
264_P269_A0.5600.48
33_A51_S0.5590.48
298_R301_L0.5590.48
119_N124_A0.5580.48
220_W294_S0.5580.48
37_W214_I0.5570.47
188_P272_I0.5550.47
52_V56_L0.5550.47
80_L239_A0.5540.47
320_Y329_L0.5530.47
20_I239_A0.5530.47
34_A223_V0.5520.47
128_Y223_V0.5490.46
278_A286_I0.5460.46
93_A139_M0.5430.46
271_Q275_L0.5430.46
136_P320_Y0.5410.45
63_K69_V0.5410.45
270_P323_G0.5410.45
51_S83_L0.5400.45
61_V67_Q0.5380.45
54_A106_V0.5380.45
330_L333_I0.5370.45
100_L104_F0.5370.45
136_P268_A0.5360.45
19_R233_W0.5350.45
248_F282_G0.5340.45
267_L271_Q0.5340.45
334_T337_L0.5330.45
129_V276_S0.5320.44
217_G222_W0.5320.44
261_L264_P0.5310.44
55_L78_A0.5300.44
231_G312_W0.5290.44
64_L107_I0.5290.44
60_L64_L0.5270.44
299_G303_F0.5270.44
19_R237_Q0.5270.44
277_G315_R0.5260.44
182_G185_Q0.5260.44
121_F125_M0.5250.44
292_T307_A0.5250.44
44_L196_V0.5240.43
251_T307_A0.5230.43
126_I190_D0.5220.43
257_M263_S0.5220.43
223_V227_W0.5210.43
243_H301_L0.5210.43
238_K242_W0.5210.43
121_F329_L0.5190.43
78_A102_T0.5180.43
128_Y218_A0.5170.43
93_A138_Q0.5170.43
112_L333_I0.5170.43
240_I245_P0.5160.43
53_S56_L0.5150.42
224_N276_S0.5140.42
26_L229_A0.5120.42
267_L316_S0.5120.42
85_L98_V0.5120.42
132_L320_Y0.5120.42
205_I209_P0.5110.42
62_L67_Q0.5100.42
41_W45_V0.5090.42
39_F211_Y0.5090.42
97_M131_L0.5090.42
257_M268_A0.5080.42
69_V111_Q0.5070.41
297_N340_Y0.5070.41
29_V229_A0.5060.41
60_L107_I0.5050.41
119_N288_T0.5040.41
252_L256_A0.5030.41
47_I50_A0.5030.41
88_S128_Y0.5010.41
79_L86_A0.5010.41
268_A271_Q0.5010.41
89_I266_T0.5000.41
130_V339_D0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4p6vB 1 0.8466 100 0.191 Contact Map
1lnqA 6 0.1989 14.6 0.973 Contact Map
4q2eA 2 0.2812 11 0.975 Contact Map
4tq3A 1 0.2585 9 0.976 Contact Map
4humA 1 0.2244 7.9 0.976 Contact Map
3mktA 1 0.2216 6.8 0.977 Contact Map
3nd0A 2 0.1562 6.3 0.977 Contact Map
3k3fA 3 0.8324 5.2 0.978 Contact Map
2l0eA 1 0.0881 3.8 0.979 Contact Map
4pd6A 3 0.3665 3.4 0.98 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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