GREMLIN Database
DOSP - Oxygen sensor protein DosP
UniProt: P76129 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13792
Length: 799 (662)
Sequences: 167 (144)
Seq/√Len: 5.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
636_L646_L4.2750.95
442_K445_Q4.0240.93
423_Y513_H4.0070.92
608_G640_H3.9960.92
423_Y454_Q3.2840.82
423_Y494_S3.0840.77
607_I773_I2.9920.75
567_A607_I2.9850.75
411_V415_Q2.9550.74
423_Y517_D2.9380.74
721_K725_D2.8950.72
575_I787_I2.7360.68
452_G513_H2.7350.68
779_S782_L2.6930.67
704_S723_F2.6320.65
410_G415_Q2.5890.63
415_Q453_T2.5780.63
580_R635_N2.5310.62
205_T230_P2.5170.61
415_Q423_Y2.5070.61
595_I704_S2.4480.59
454_Q513_H2.4160.58
494_S517_D2.4080.57
412_D494_S2.3420.55
513_H517_D2.3200.54
410_G423_Y2.3150.54
423_Y452_G2.3100.54
418_I453_T2.3070.54
702_G709_L2.2660.53
581_W587_G2.2370.52
595_I723_F2.2340.52
454_Q517_D2.1970.50
364_E641_F2.1770.50
578_L670_E2.1650.49
410_G419_D2.1180.48
718_K754_E2.1070.47
618_Q641_F2.1030.47
433_V749_L2.1000.47
561_Y615_A2.0950.47
674_M771_R2.0880.47
653_A657_W2.0840.46
600_E721_K2.0700.46
415_Q517_D2.0350.45
138_L146_D2.0220.44
541_R557_L2.0090.44
381_M453_T2.0070.44
248_I252_R1.9960.43
581_W702_G1.9950.43
440_K472_D1.9870.43
604_I699_F1.9860.43
745_Q771_R1.9840.43
736_L743_I1.9830.43
635_N667_E1.9810.43
423_Y516_M1.9800.43
669_T699_F1.9720.43
699_F723_F1.9490.42
580_R667_E1.9240.41
720_D754_E1.9190.41
410_G517_D1.8830.40
667_E718_K1.8770.39
698_D754_E1.8740.39
608_G739_A1.8620.39
599_E637_S1.8520.39
670_E718_K1.8360.38
409_I569_T1.8270.38
594_F670_E1.8240.38
410_G520_R1.8220.38
164_A451_E1.8090.37
578_L594_F1.8070.37
162_N228_I1.8050.37
587_G610_W1.7930.37
640_H719_I1.7900.37
332_G335_Q1.7900.37
494_S598_A1.7760.36
249_T646_L1.7750.36
604_I704_S1.7710.36
390_L595_I1.7690.36
252_R255_R1.7670.36
147_R246_S1.7560.36
381_M513_H1.7550.36
578_L718_K1.7370.35
633_S745_Q1.7330.35
640_H790_W1.7300.35
589_V607_I1.7210.34
557_L790_W1.7030.34
453_T520_R1.7010.34
670_E698_D1.6990.34
510_S616_C1.6890.33
667_E754_E1.6790.33
578_L698_D1.6790.33
591_P594_F1.6790.33
542_L740_I1.6770.33
599_E699_F1.6740.33
580_R718_K1.6740.33
248_I622_W1.6700.33
583_D659_I1.6700.33
162_N190_F1.6690.33
670_E754_E1.6660.33
578_L754_E1.6660.33
576_E635_N1.6590.33
635_N718_K1.6580.33
638_A674_M1.6560.32
415_Q512_A1.6500.32
540_E593_R1.6460.32
570_G650_V1.6450.32
618_Q694_L1.6360.32
667_E720_D1.6300.32
704_S709_L1.6270.32
597_L643_S1.6180.31
699_F718_K1.6040.31
146_D676_H1.6020.31
576_E697_D1.6020.31
381_M452_G1.5940.31
592_S695_S1.5940.31
528_Q607_I1.5870.30
412_D452_G1.5810.30
493_L644_N1.5800.30
389_N717_I1.5780.30
219_G383_G1.5760.30
670_E720_D1.5740.30
449_R453_T1.5560.30
669_T723_F1.5550.29
530_F581_W1.5470.29
150_I243_M1.5410.29
608_G704_S1.5390.29
581_W610_W1.5330.29
410_G453_T1.5320.29
584_P587_G1.5310.29
449_R520_R1.5310.29
494_S513_H1.5300.29
214_L744_G1.5290.29
630_P665_T1.5280.29
580_R720_D1.5280.29
410_G451_E1.5240.29
171_Y217_R1.5200.29
410_G418_I1.5170.28
407_Y530_F1.5140.28
710_V733_I1.5070.28
576_E580_R1.5050.28
578_L720_D1.5000.28
560_V744_G1.5000.28
143_D163_R1.4990.28
712_L743_I1.4930.28
211_E248_I1.4890.28
516_M633_S1.4880.28
635_N720_D1.4800.27
523_G530_F1.4760.27
756_V773_I1.4690.27
360_A572_L1.4680.27
580_R754_E1.4670.27
519_I581_W1.4630.27
412_D598_A1.4620.27
418_I520_R1.4580.27
390_L570_G1.4520.27
150_I158_I1.4480.27
597_L780_R1.4420.26
247_D753_A1.4410.26
561_Y631_A1.4380.26
755_G774_Q1.4310.26
432_E752_V1.4300.26
286_L294_F1.4250.26
719_I770_C1.4230.26
635_N754_E1.4180.26
712_L736_L1.4150.26
640_H740_I1.4080.25
415_Q454_Q1.4060.25
467_I638_A1.4030.25
378_F632_L1.4010.25
699_F720_D1.4000.25
596_P696_V1.4000.25
333_I344_T1.3990.25
699_F754_E1.3970.25
387_R423_Y1.3960.25
538_V696_V1.3930.25
160_Q435_N1.3920.25
594_F718_K1.3880.25
594_F754_E1.3860.25
594_F698_D1.3850.25
495_I516_M1.3850.25
559_L610_W1.3770.25
699_F706_L1.3770.25
578_L667_E1.3750.25
231_V363_L1.3720.25
710_V776_Y1.3700.25
604_I669_T1.3660.24
501_L529_F1.3620.24
227_S457_L1.3590.24
329_A332_G1.3590.24
406_V529_F1.3530.24
412_D423_Y1.3520.24
387_R451_E1.3510.24
587_G701_T1.3510.24
667_E670_E1.3490.24
409_I781_P1.3370.24
381_M418_I1.3370.24
333_I358_M1.3360.24
622_W724_V1.3340.24
595_I608_G1.3330.24
693_G715_T1.3280.23
756_V770_C1.3280.23
408_L442_K1.3250.23
282_I287_N1.3240.23
654_M692_V1.3220.23
581_W599_E1.3180.23
452_G494_S1.3140.23
375_L706_L1.3130.23
661_G783_P1.3110.23
405_V467_I1.3080.23
408_L618_Q1.3070.23
515_A581_W1.3050.23
411_V414_I1.3010.23
610_W701_T1.2980.23
758_T761_Q1.2950.23
667_E781_P1.2940.23
515_A702_G1.2930.23
694_L784_A1.2830.22
756_V765_L1.2790.22
453_T513_H1.2790.22
494_S561_Y1.2790.22
638_A770_C1.2790.22
597_L611_V1.2740.22
608_G740_I1.2700.22
297_R776_Y1.2610.22
270_P293_L1.2560.22
248_I756_V1.2550.22
387_R512_A1.2540.22
475_R516_M1.2530.22
698_D718_K1.2510.22
545_G643_S1.2490.22
421_L610_W1.2460.21
518_Y636_L1.2450.21
454_Q494_S1.2400.21
714_V727_C1.2380.21
654_M690_M1.2300.21
358_M516_M1.2270.21
415_Q513_H1.2270.21
599_E669_T1.2260.21
581_W598_A1.2210.21
594_F720_D1.2210.21
451_E517_D1.2200.21
418_I449_R1.2180.21
616_C739_A1.2170.21
372_I707_S1.2160.21
477_V493_L1.2150.21
390_L750_T1.2150.21
510_S633_S1.2080.21
415_Q426_A1.2070.21
278_I758_T1.2070.21
278_I286_L1.2060.21
599_E604_I1.2050.21
419_D513_H1.2040.21
137_Q377_Q1.2020.20
600_E608_G1.1980.20
618_Q778_F1.1980.20
776_Y781_P1.1950.20
667_E700_G1.1940.20
741_T771_R1.1940.20
365_Q408_L1.1910.20
608_G723_F1.1890.20
698_D704_S1.1880.20
478_V653_A1.1860.20
567_A773_I1.1860.20
402_V658_G1.1840.20
604_I723_F1.1780.20
457_L624_S1.1780.20
580_R670_E1.1770.20
447_L671_S1.1630.20
581_W584_P1.1600.20
667_E757_E1.1580.20
297_R787_I1.1570.19
485_D767_K1.1570.19
372_I564_Q1.1570.19
530_F784_A1.1540.19
595_I699_F1.1510.19
248_I457_L1.1510.19
578_L700_G1.1490.19
295_A473_E1.1470.19
403_S444_D1.1440.19
219_G328_G1.1420.19
667_E706_L1.1400.19
618_Q646_L1.1400.19
429_A482_I1.1360.19
583_D587_G1.1360.19
598_A709_L1.1350.19
572_L623_R1.1310.19
581_W637_S1.1280.19
471_A583_D1.1270.19
614_E618_Q1.1250.19
137_Q148_P1.1240.19
667_E697_D1.1230.19
516_M573_Y1.1190.19
578_L635_N1.1180.19
558_K582_H1.1150.19
579_A611_V1.1140.19
560_V763_E1.1130.19
613_A657_W1.1100.19
669_T718_K1.1100.19
153_D198_L1.1070.18
412_D564_Q1.1010.18
372_I557_L1.1010.18
418_I426_A1.0990.18
701_T723_F1.0960.18
491_L684_I1.0950.18
410_G717_I1.0950.18
674_M696_V1.0900.18
635_N670_E1.0890.18
501_L714_V1.0870.18
419_D449_R1.0870.18
429_A508_L1.0820.18
698_D720_D1.0820.18
398_V687_L1.0760.18
351_V761_Q1.0750.18
492_T642_R1.0740.18
369_R378_F1.0700.18
669_T709_L1.0680.18
601_I719_I1.0650.18
727_C737_L1.0640.18
417_V425_W1.0640.18
223_W252_R1.0630.18
134_Q137_Q1.0600.17
670_E700_G1.0590.17
381_M412_D1.0580.17
418_I454_Q1.0510.17
570_G671_S1.0490.17
381_M454_Q1.0480.17
578_L591_P1.0480.17
134_Q456_V1.0480.17
456_V736_L1.0460.17
699_F753_A1.0450.17
378_F556_Q1.0410.17
252_R723_F1.0380.17
594_F667_E1.0350.17
667_E774_Q1.0340.17
365_Q423_Y1.0330.17
383_G739_A1.0330.17
580_R781_P1.0320.17
621_E658_G1.0320.17
561_Y618_Q1.0290.17
667_E699_F1.0290.17
263_A557_L1.0280.17
635_N781_P1.0280.17
447_L459_S1.0260.17
157_H232_Y1.0230.17
376_I705_G1.0210.17
718_K781_P1.0200.17
138_L153_D1.0190.17
203_W727_C1.0160.17
316_A484_I1.0130.17
759_K777_F1.0100.17
478_V507_Y1.0070.16
320_S459_S1.0070.16
298_N566_F1.0070.16
669_T698_D1.0050.16
445_Q473_E1.0020.16
633_S737_L1.0010.16
669_T720_D1.0010.16
583_D598_A1.0010.16
635_N757_E0.9980.16
231_V483_M0.9980.16
397_L411_V0.9970.16
403_S442_K0.9960.16
542_L665_T0.9960.16
635_N697_D0.9960.16
149_V492_T0.9950.16
578_L699_F0.9950.16
471_A780_R0.9950.16
348_I437_F0.9930.16
200_Q266_C0.9890.16
231_V474_L0.9880.16
595_I698_D0.9840.16
248_I706_L0.9830.16
641_F694_L0.9810.16
389_N393_Y0.9800.16
386_N563_P0.9800.16
591_P670_E0.9790.16
578_L669_T0.9780.16
223_W602_G0.9780.16
637_S770_C0.9780.16
614_E741_T0.9780.16
392_N470_I0.9750.16
162_N178_G0.9750.16
511_T557_L0.9720.16
407_Y495_I0.9720.16
164_A246_S0.9690.16
452_G517_D0.9660.16
687_L764_M0.9660.16
595_I776_Y0.9650.16
597_L696_V0.9650.16
704_S718_K0.9630.16
783_P786_E0.9620.16
516_M714_V0.9590.16
323_I340_S0.9590.16
670_E699_F0.9590.16
557_L579_A0.9570.16
372_I641_F0.9570.16
190_F213_L0.9570.16
570_G783_P0.9570.16
646_L744_G0.9560.16
249_T375_L0.9550.16
697_D720_D0.9550.16
599_E757_E0.9550.16
328_G332_G0.9530.15
443_P473_E0.9500.15
415_Q451_E0.9500.15
407_Y471_A0.9480.15
456_V509_L0.9470.15
488_P554_N0.9460.15
635_N700_G0.9460.15
504_N507_Y0.9450.15
291_V294_F0.9440.15
599_E667_E0.9440.15
432_E634_V0.9430.15
454_Q520_R0.9350.15
412_D513_H0.9340.15
448_C719_I0.9340.15
164_A719_I0.9330.15
621_E625_Q0.9320.15
222_I434_V0.9310.15
561_Y608_G0.9290.15
562_Q700_G0.9260.15
587_G654_M0.9250.15
385_P550_E0.9240.15
436_R713_P0.9220.15
410_G512_A0.9220.15
630_P743_I0.9200.15
580_R706_L0.9160.15
563_P747_L0.9140.15
389_N632_L0.9130.15
390_L458_V0.9120.15
414_I520_R0.9120.15
669_T777_F0.9110.15
258_E261_I0.9100.15
421_L723_F0.9090.15
654_M739_A0.9080.15
385_P436_R0.9070.15
719_I740_I0.9070.15
394_L533_A0.9070.15
415_Q452_G0.9050.15
252_R583_D0.9040.15
148_P166_T0.9040.15
632_L721_K0.9040.15
319_W661_G0.9020.15
250_E447_L0.9010.15
650_V784_A0.9010.15
757_E781_P0.8990.15
297_R328_G0.8980.15
270_P292_S0.8970.14
706_L718_K0.8960.14
377_Q530_F0.8950.14
414_I654_M0.8950.14
595_I641_F0.8950.14
450_I665_T0.8940.14
698_D781_P0.8940.14
257_L684_I0.8940.14
633_S661_G0.8930.14
697_D718_K0.8900.14
343_E465_S0.8890.14
372_I716_E0.8860.14
411_V545_G0.8840.14
288_E294_F0.8830.14
576_E667_E0.8830.14
378_F517_D0.8820.14
344_T358_M0.8820.14
427_D449_R0.8820.14
628_H676_H0.8810.14
179_M737_L0.8780.14
667_E698_D0.8770.14
635_N706_L0.8760.14
719_I736_L0.8750.14
423_Y453_T0.8730.14
607_I727_C0.8720.14
408_L516_M0.8720.14
254_I617_R0.8710.14
669_T754_E0.8710.14
472_D619_L0.8690.14
248_I574_G0.8680.14
412_D739_A0.8680.14
741_T777_F0.8660.14
667_E755_G0.8660.14
188_P771_R0.8650.14
408_L717_I0.8640.14
613_A656_A0.8620.14
616_C659_I0.8610.14
616_C761_Q0.8590.14
700_G757_E0.8590.14
674_M727_C0.8570.14
623_R660_D0.8560.14
376_I712_L0.8540.14
332_G341_G0.8530.14
551_A756_V0.8500.14
719_I743_I0.8490.14
698_D722_S0.8480.14
667_E705_G0.8470.14
335_Q341_G0.8440.14
547_A736_L0.8440.14
635_N705_G0.8410.14
530_F780_R0.8400.14
365_Q415_Q0.8400.14
147_R164_A0.8390.14
580_R594_F0.8360.13
660_D750_T0.8350.13
704_S754_E0.8320.13
364_E749_L0.8300.13
485_D597_L0.8300.13
138_L694_L0.8290.13
665_T743_I0.8290.13
133_E417_V0.8270.13
336_I434_V0.8270.13
606_N687_L0.8240.13
580_R774_Q0.8230.13
608_G637_S0.8210.13
387_R517_D0.8200.13
447_L474_L0.8190.13
668_I724_V0.8190.13
608_G761_Q0.8170.13
176_A681_F0.8160.13
559_L701_T0.8160.13
699_F765_L0.8140.13
427_D520_R0.8140.13
406_V446_Y0.8130.13
556_Q584_P0.8110.13
486_D721_K0.8100.13
372_I743_I0.8100.13
646_L694_L0.8100.13
254_I676_H0.8070.13
410_G449_R0.8060.13
580_R697_D0.8020.13
419_D453_T0.8020.13
448_C671_S0.8010.13
591_P718_K0.8010.13
491_L788_P0.8000.13
461_E632_L0.7980.13
580_R700_G0.7980.13
580_R699_F0.7970.13
587_G702_G0.7960.13
387_R410_G0.7950.13
250_E575_I0.7950.13
580_R757_E0.7940.13
194_N406_V0.7940.13
572_L628_H0.7940.13
463_D477_V0.7930.13
165_F217_R0.7920.13
408_L414_I0.7920.13
227_S246_S0.7910.13
192_A786_E0.7870.13
722_S744_G0.7870.13
230_P766_R0.7860.13
139_I165_F0.7840.13
379_D496_G0.7830.13
379_D775_G0.7830.13
496_G775_G0.7830.13
288_E298_N0.7820.13
724_V744_G0.7810.13
604_I720_D0.7800.13
544_L702_G0.7800.13
594_F700_G0.7800.13
169_F185_L0.7790.13
555_N634_V0.7790.13
733_I744_G0.7790.13
564_Q631_A0.7780.13
398_V529_F0.7780.13
132_K467_I0.7770.13
635_N699_F0.7760.13
637_S699_F0.7760.13
580_R705_G0.7760.13
489_F626_N0.7750.13
739_A744_G0.7740.13
700_G718_K0.7740.13
333_I337_K0.7710.12
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415_Q418_I0.7640.12
635_N774_Q0.7640.12
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540_E690_M0.7560.12
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559_L731_K0.6110.10
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379_D422_G0.6110.10
422_G496_G0.6110.10
422_G775_G0.6110.10
697_D755_G0.6100.10
365_Q641_F0.6100.10
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309_H317_Q0.6080.10
640_H723_F0.6080.10
572_L734_L0.6060.10
667_E704_S0.6060.10
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298_N477_V0.6040.10
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671_S719_I0.6010.10
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242_V257_L0.5970.10
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381_M405_V0.5960.10
331_A344_T0.5960.10
410_G426_A0.5950.10
722_S754_E0.5950.10
713_P743_I0.5940.10
635_N755_G0.5930.10
293_L500_D0.5930.10
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382_T578_L0.5920.10
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499_Y545_G0.5910.10
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175_E480_K0.5850.10
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342_A642_R0.5820.10
411_V423_Y0.5810.10
541_R650_V0.5810.10
160_Q682_K0.5800.10
426_A513_H0.5800.10
494_S581_W0.5780.10
384_L523_G0.5760.10
379_D386_N0.5760.10
386_N496_G0.5760.10
386_N775_G0.5760.10
148_P416_D0.5750.10
272_H789_G0.5740.10
219_G320_S0.5740.10
580_R599_E0.5730.10
603_E606_N0.5720.10
365_Q517_D0.5720.10
576_E720_D0.5720.10
415_Q520_R0.5710.10
724_V753_A0.5700.10
162_N668_I0.5700.10
162_N670_E0.5700.10
165_F246_S0.5700.10
687_L753_A0.5700.10
360_A727_C0.5690.10
223_W372_I0.5690.10
186_N212_F0.5690.10
427_D453_T0.5690.10
666_V705_G0.5680.10
699_F704_S0.5680.10
521_K692_V0.5670.10
183_T752_V0.5660.10
320_S323_I0.5660.10
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426_A453_T0.5660.10
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515_A587_G0.5650.10
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597_L654_M0.5520.10
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481_P575_I0.5510.10
375_L482_I0.5500.10
324_R634_V0.5490.10
405_V492_T0.5490.10
700_G781_P0.5490.10
618_Q659_I0.5480.09
451_E454_Q0.5470.09
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551_A770_C0.5420.09
720_D774_Q0.5420.09
178_G213_L0.5410.09
608_G633_S0.5410.09
599_E765_L0.5410.09
509_L768_I0.5400.09
182_D228_I0.5390.09
688_R715_T0.5390.09
576_E718_K0.5390.09
142_V264_A0.5370.09
248_I557_L0.5360.09
519_I587_G0.5360.09
721_K759_K0.5340.09
132_K224_I0.5330.09
580_R776_Y0.5330.09
436_R581_W0.5320.09
641_F740_I0.5320.09
175_E428_Q0.5310.09
581_W770_C0.5310.09
601_I673_M0.5300.09
423_Y451_E0.5300.09
303_H661_G0.5290.09
530_F598_A0.5290.09
133_E136_R0.5280.09
294_F783_P0.5280.09
379_D774_Q0.5280.09
496_G774_Q0.5280.09
332_G337_K0.5270.09
387_R577_A0.5270.09
411_V752_V0.5270.09
459_S492_T0.5250.09
700_G720_D0.5240.09
599_E709_L0.5240.09
355_S719_I0.5240.09
467_I475_R0.5230.09
382_T418_I0.5230.09
599_E702_G0.5230.09
172_C534_M0.5230.09
619_L724_V0.5230.09
706_L723_F0.5220.09
159_V780_R0.5220.09
754_E774_Q0.5210.09
163_R613_A0.5200.09
252_R776_Y0.5200.09
167_E624_S0.5190.09
415_Q494_S0.5190.09
479_S590_P0.5180.09
394_L429_A0.5180.09
610_W638_A0.5170.09
273_E668_I0.5170.09
752_V781_P0.5160.09
396_D571_E0.5150.09
213_L223_W0.5150.09
598_A618_Q0.5150.09
414_I561_Y0.5140.09
471_A584_P0.5130.09
752_V758_T0.5120.09
414_I744_G0.5120.09
449_R513_H0.5120.09
498_S671_S0.5110.09
740_I761_Q0.5110.09
139_I144_H0.5100.09
564_Q710_V0.5100.09
249_T518_Y0.5090.09
211_E238_L0.5090.09
774_Q781_P0.5080.09
185_L202_L0.5070.09
546_A745_Q0.5050.09
637_S669_T0.5050.09
244_T682_K0.5030.09
162_N718_K0.5030.09
368_S375_L0.5010.09
160_Q244_T0.5010.09
737_L782_L0.5010.09
502_G509_L0.5010.09
379_D562_Q0.5000.09
496_G562_Q0.5000.09
562_Q775_G0.5000.09
578_L595_I0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rnhA 2 0.5156 100 0.526 Contact Map
4j40A 2 0.3141 100 0.531 Contact Map
3pjxA 1 0.5181 100 0.543 Contact Map
3gfzA 2 0.4693 100 0.596 Contact Map
4hjfA 1 0.3267 100 0.628 Contact Map
4hu4A 1 0.3091 100 0.681 Contact Map
4kieA 1 0.3267 100 0.685 Contact Map
3sy8A 6 0.4844 100 0.689 Contact Map
2r6oA 2 0.3217 100 0.691 Contact Map
4rniA 2 0.3179 100 0.693 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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