GREMLIN Database
YDDH - Uncharacterized protein YddH
UniProt: P76121 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13779
Length: 189 (168)
Sequences: 3968 (2861)
Seq/√Len: 220.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
105_P120_K3.9401.00
111_V147_V3.4561.00
72_F144_G3.4191.00
128_R145_E3.1961.00
29_E33_R3.1361.00
79_V169_N2.8891.00
128_R147_V2.8071.00
30_Q68_H2.5861.00
107_V118_E2.5431.00
130_L145_E2.4811.00
97_D100_N2.3251.00
34_R106_V2.3071.00
25_T73_G2.3071.00
67_E132_A2.1061.00
36_I117_V2.0841.00
27_F34_R2.0691.00
79_V181_T2.0231.00
71_K128_R2.0141.00
77_P85_T2.0141.00
109_G116_L2.0061.00
92_S101_C2.0001.00
105_P118_E1.9921.00
73_G112_F1.8921.00
53_A141_T1.8541.00
99_F106_V1.8101.00
27_F113_G1.7321.00
52_V74_I1.6961.00
116_L124_W1.6851.00
71_K113_G1.6191.00
64_E94_R1.5891.00
109_G126_E1.5551.00
25_T36_I1.5501.00
34_R115_P1.5401.00
45_V53_A1.5361.00
92_S96_E1.5281.00
110_P148_S1.5141.00
112_F126_E1.5001.00
51_R143_F1.4721.00
23_L36_I1.4721.00
172_H180_V1.4501.00
72_F127_C1.4281.00
12_A44_P1.3861.00
132_A140_D1.3581.00
23_L88_V1.3511.00
78_G81_A1.3491.00
51_R130_L1.3491.00
109_G114_L1.3471.00
181_T184_K1.3301.00
157_V164_D1.3251.00
66_I129_L1.3021.00
64_E68_H1.2771.00
109_G112_F1.2711.00
77_P171_L1.2601.00
116_L150_A1.2591.00
125_M146_V1.2471.00
97_D106_V1.2401.00
111_V148_S1.2321.00
15_L123_A1.2241.00
63_R67_E1.2231.00
71_K112_F1.1941.00
37_M62_T1.1781.00
66_I72_F1.1761.00
157_V167_K1.1681.00
26_S66_I1.1651.00
75_V124_W1.1561.00
45_V143_F1.1551.00
164_D167_K1.1541.00
81_A120_K1.1511.00
36_I99_F1.1271.00
34_R97_D1.0981.00
125_M149_A1.0881.00
107_V116_L1.0881.00
82_T171_L1.0821.00
80_A169_N1.0561.00
77_P121_C1.0501.00
22_V42_S1.0481.00
26_S65_L1.0321.00
127_C144_G1.0281.00
174_L180_V1.0281.00
96_E101_C1.0281.00
129_L132_A1.0231.00
63_R140_D1.0211.00
52_V125_M1.0171.00
88_V102_Y1.0151.00
58_K134_S1.0081.00
61_W94_R1.0001.00
58_K140_D0.9761.00
73_G116_L0.9701.00
84_W102_Y0.9671.00
172_H182_S0.9611.00
155_V168_L0.9531.00
129_L142_L0.9521.00
63_R142_L0.9491.00
23_L81_A0.9491.00
84_W104_I0.9481.00
132_A142_L0.9321.00
78_G122_L0.9281.00
43_M53_A0.9160.99
169_N181_T0.8990.99
26_S62_T0.8930.99
61_W64_E0.8900.99
151_A155_V0.8790.99
52_V146_V0.8740.99
39_A54_I0.8660.99
39_A56_V0.8650.99
157_V162_Q0.8610.99
133_T143_F0.8610.99
69_N113_G0.8540.99
152_D155_V0.8520.99
27_F108_R0.8470.99
73_G109_G0.8460.99
24_I54_I0.8430.99
134_S140_D0.8360.99
27_F114_L0.8340.99
87_A92_S0.8260.99
107_V124_W0.8200.99
79_V82_T0.8160.99
73_G124_W0.8150.99
27_F69_N0.8070.99
87_A101_C0.8040.99
29_E32_Q0.7990.99
61_W65_L0.7940.98
47_F57_D0.7900.98
25_T117_V0.7800.98
33_R95_D0.7800.98
71_K114_L0.7790.98
57_D139_Y0.7790.98
53_A143_F0.7750.98
108_R113_G0.7750.98
46_E135_A0.7740.98
45_V51_R0.7740.98
65_L69_N0.7720.98
123_A168_L0.7690.98
22_V74_I0.7670.98
74_I127_C0.7600.98
165_D170_T0.7470.98
34_R99_F0.7440.98
76_I168_L0.7420.98
25_T75_V0.7350.97
54_I142_L0.7350.97
46_E139_Y0.7330.97
155_V163_F0.7310.97
122_L152_D0.7300.97
87_A102_Y0.7300.97
80_A122_L0.7260.97
16_L44_P0.7130.97
135_A143_F0.7120.97
105_P117_V0.7100.97
67_E134_S0.7090.97
174_L178_T0.7060.97
111_V126_E0.7040.97
155_V167_K0.7010.97
85_T171_L0.6980.97
29_E68_H0.6940.96
45_V55_V0.6940.96
25_T114_L0.6920.96
76_I170_T0.6890.96
23_L121_C0.6880.96
81_A121_C0.6860.96
67_E70_G0.6840.96
33_R94_R0.6820.96
70_G128_R0.6800.96
117_V120_K0.6780.96
75_V117_V0.6770.96
83_N87_A0.6770.96
85_T121_C0.6740.96
23_L117_V0.6720.96
25_T99_F0.6660.95
84_W120_K0.6650.95
170_T182_S0.6640.95
87_A96_E0.6630.95
45_V141_T0.6540.95
154_R167_K0.6530.95
124_W150_A0.6530.95
70_G129_L0.6520.95
76_I123_A0.6520.95
17_N170_T0.6460.95
131_P134_S0.6400.94
71_K126_E0.6380.94
16_L76_I0.6310.94
62_T65_L0.6310.94
107_V110_P0.6270.94
92_S98_K0.6270.94
34_R114_L0.6270.94
55_V139_Y0.6230.94
174_L182_S0.6190.93
42_S53_A0.6180.93
66_I144_G0.6130.93
109_G124_W0.6100.93
106_V120_K0.6070.93
63_R132_A0.6060.93
15_L125_M0.6040.92
159_G162_Q0.6000.92
61_W98_K0.5980.92
51_R135_A0.5980.92
55_V141_T0.5970.92
43_M55_V0.5970.92
42_S76_I0.5940.92
43_M141_T0.5930.92
73_G114_L0.5900.92
23_L85_T0.5860.91
87_A90_S0.5850.91
16_L52_V0.5840.91
41_W44_P0.5760.91
165_D174_L0.5750.91
21_T38_A0.5730.90
100_N103_G0.5710.90
110_P126_E0.5680.90
111_V128_R0.5680.90
58_K63_R0.5680.90
16_L22_V0.5680.90
166_D184_K0.5620.90
13_S47_F0.5610.89
56_V142_L0.5600.89
39_A62_T0.5550.89
106_V115_P0.5550.89
104_I117_V0.5530.89
23_L104_I0.5530.89
24_I39_A0.5520.89
46_E51_R0.5520.89
27_F32_Q0.5510.89
99_F102_Y0.5510.89
38_A77_P0.5500.89
81_A104_I0.5500.89
163_F168_L0.5460.88
108_R115_P0.5450.88
93_G98_K0.5420.88
110_P150_A0.5410.88
64_E67_E0.5410.88
59_S63_R0.5410.88
26_S37_M0.5410.88
93_G96_E0.5370.87
14_R175_G0.5360.87
86_W90_S0.5330.87
54_I66_I0.5330.87
130_L143_F0.5320.87
115_P146_V0.5290.87
89_G92_S0.5250.86
102_Y117_V0.5240.86
86_W179_F0.5240.86
123_A151_A0.5230.86
15_L149_A0.5200.86
155_V165_D0.5170.85
100_N106_V0.5170.85
17_N165_D0.5130.85
46_E57_D0.5120.85
156_F163_F0.5090.84
104_I120_K0.5090.84
33_R61_W0.5050.84
36_I88_V0.5030.84
80_A154_R0.5020.84
89_G98_K0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bpkA 2 0.9683 100 0.248 Contact Map
3fgeA 2 0.9841 100 0.268 Contact Map
3hmzA 2 0.9683 100 0.275 Contact Map
2r6vA 2 0.9524 100 0.291 Contact Map
1ejeA 2 0.9683 100 0.294 Contact Map
2d5mA 2 0.9365 100 0.302 Contact Map
3e4vA 2 0.9101 100 0.327 Contact Map
3bnkA 2 0.9365 100 0.34 Contact Map
1uscA 2 0.9365 100 0.354 Contact Map
3cb0A 2 0.8571 100 0.417 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0069 seconds.