GREMLIN Database
YNCG - Uncharacterized GST-like protein YncG
UniProt: P76117 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13777
Length: 205 (192)
Sequences: 21624 (14727)
Seq/√Len: 1062.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
21_L192_L3.6761.00
72_L94_Q3.3631.00
3_K29_V3.1761.00
76_D90_R3.0701.00
184_A188_A3.0541.00
19_L26_Y3.0361.00
20_T197_E2.8041.00
138_I179_A2.6841.00
3_K27_Q2.6041.00
62_E88_A2.5681.00
6_G12_S2.5491.00
20_T26_Y2.3641.00
45_K51_C2.3431.00
3_K57_A2.2391.00
145_T181_N2.2211.00
148_P188_A2.2051.00
141_N181_N2.1871.00
57_A63_I2.1041.00
22_A75_L2.0521.00
21_L194_K1.9701.00
134_K178_N1.9191.00
86_G89_E1.9111.00
5_Y57_A1.8931.00
18_M71_A1.8721.00
42_E46_T1.8651.00
127_K131_E1.7821.00
76_D94_Q1.7811.00
47_L57_A1.7781.00
155_L160_C1.7551.00
92_L95_R1.7481.00
123_E127_K1.7391.00
148_P153_E1.7311.00
183_S187_D1.6731.00
57_A61_D1.6541.00
47_L55_T1.6321.00
17_L195_L1.5991.00
163_C189_V1.5571.00
44_L55_T1.5511.00
181_N184_A1.5451.00
96_L143_Q1.5211.00
5_Y31_V1.5131.00
38_G41_R1.5081.00
43_L46_T1.4881.00
138_I142_S1.4621.00
155_L192_L1.4531.00
24_I78_R1.4491.00
6_G28_F1.4071.00
84_P93_F1.3911.00
187_D191_Q1.3861.00
44_L47_L1.3761.00
151_F156_T1.3321.00
83_P93_F1.3081.00
14_I67_T1.3041.00
40_S51_C1.3031.00
150_A162_L1.2971.00
143_Q147_E1.2831.00
130_I134_K1.2751.00
65_T95_R1.2671.00
72_L98_V1.2441.00
98_V101_V1.2441.00
18_M22_A1.2391.00
191_Q196_Q1.2341.00
4_V19_L1.2191.00
177_D183_S1.2161.00
186_A190_C1.2131.00
155_L189_V1.1901.00
18_M82_A1.1851.00
138_I178_N1.1851.00
15_S71_A1.1701.00
64_M91_Q1.1521.00
40_S45_K1.1451.00
88_A92_L1.1431.00
193_P197_E1.1261.00
132_Y135_S1.1051.00
21_L155_L1.1031.00
100_L162_L1.0961.00
52_Q66_E1.0921.00
22_A74_V1.0901.00
149_Y189_V1.0891.00
97_L161_Y1.0881.00
141_N145_T1.0881.00
77_R87_R1.0841.00
82_A160_C1.0731.00
134_K179_A1.0721.00
71_A157_L1.0621.00
141_N180_T1.0481.00
14_I161_Y1.0251.00
142_S145_T1.0111.00
50_L99_W1.0051.00
127_K130_I1.0041.00
131_E135_S0.9991.00
163_C190_C0.9961.00
12_S53_V0.9961.00
187_D190_C0.9921.00
22_A79_P0.9881.00
48_N55_T0.9851.00
149_Y188_A0.9781.00
135_S138_I0.9721.00
148_P184_A0.9681.00
87_R91_Q0.9631.00
32_S39_A0.9611.00
175_F178_N0.9601.00
98_V102_A0.9481.00
44_L48_N0.9481.00
134_K138_I0.9401.00
89_E92_L0.9371.00
122_P125_L0.9361.00
193_P196_Q0.9311.00
47_L63_I0.9271.00
188_A191_Q0.9211.00
89_E154_Q0.9191.00
124_Q127_K0.9121.00
131_E134_K0.8981.00
92_L143_Q0.8941.00
71_A161_Y0.8841.00
68_A98_V0.8841.00
139_W143_Q0.8841.00
163_C195_L0.8831.00
185_I189_V0.8811.00
166_R185_I0.8761.00
83_P94_Q0.8751.00
74_V78_R0.8741.00
50_L65_T0.8741.00
17_L160_C0.8671.00
97_L157_L0.8621.00
170_P186_A0.8621.00
16_E28_F0.8601.00
15_S70_I0.8551.00
184_A187_D0.8491.00
21_L160_C0.8441.00
93_F151_F0.8421.00
93_F156_T0.8361.00
55_T63_I0.8351.00
93_F157_L0.8331.00
9_G12_S0.8321.00
6_G16_E0.8201.00
81_L154_Q0.8191.00
69_A95_R0.8181.00
42_E45_K0.8161.00
146_A181_N0.8141.00
33_G39_A0.8141.00
62_E92_L0.8141.00
96_L99_W0.8141.00
147_E153_E0.8121.00
150_A185_I0.8111.00
150_A158_V0.8101.00
68_A161_Y0.8091.00
121_A126_K0.8091.00
16_E20_T0.8081.00
62_E91_Q0.8071.00
14_I71_A0.8011.00
59_E77_R0.7971.00
128_N131_E0.7971.00
99_W136_L0.7961.00
92_L96_L0.7951.00
68_A101_V0.7941.00
31_V38_G0.7911.00
73_M77_R0.7901.00
128_N132_Y0.7851.00
8_P30_D0.7831.00
93_F158_V0.7821.00
167_T190_C0.7811.00
17_L164_T0.7791.00
114_P118_A0.7781.00
81_L85_V0.7711.00
4_V16_E0.7701.00
84_P89_E0.7671.00
22_A81_L0.7621.00
139_W142_S0.7601.00
41_R45_K0.7491.00
22_A78_R0.7491.00
141_N179_A0.7441.00
92_L147_E0.7441.00
72_L76_D0.7371.00
55_T65_T0.7361.00
66_E103_N0.7361.00
69_A91_Q0.7321.00
90_R94_Q0.7311.00
166_R186_A0.7301.00
18_M160_C0.7251.00
107_T110_F0.7231.00
140_L162_L0.7181.00
167_T195_L0.7121.00
129_V132_Y0.7081.00
13_T198_V0.7071.00
5_Y29_V0.7061.00
17_L163_C0.7001.00
75_L81_L0.6991.00
17_L194_K0.6961.00
141_N182_I0.6961.00
11_G14_I0.6921.00
179_A182_I0.6891.00
18_M75_L0.6891.00
149_Y155_L0.6871.00
109_T113_Y0.6851.00
113_Y124_Q0.6831.00
123_E126_K0.6761.00
143_Q150_A0.6731.00
138_I141_N0.6731.00
75_L83_P0.6721.00
56_L74_V0.6651.00
60_N88_A0.6621.00
143_Q146_A0.6611.00
41_R44_L0.6581.00
140_L182_I0.6531.00
178_N183_S0.6511.00
137_Y179_A0.6411.00
4_V56_L0.6381.00
107_T136_L0.6351.00
89_E151_F0.6351.00
61_D88_A0.6321.00
149_Y159_D0.6281.00
170_P190_C0.6221.00
137_Y182_I0.6211.00
29_V38_G0.6181.00
69_A98_V0.6171.00
5_Y47_L0.6151.00
14_I68_A0.6141.00
90_R93_F0.6131.00
108_F133_R0.6101.00
62_E73_M0.6081.00
147_E188_A0.6081.00
16_E198_V0.6061.00
11_G105_Y0.6021.00
83_P157_L0.6011.00
32_S38_G0.5991.00
4_V15_S0.5951.00
126_K130_I0.5931.00
76_D87_R0.5911.00
124_Q128_N0.5901.00
64_M70_I0.5881.00
125_L129_V0.5871.00
151_F158_V0.5871.00
152_G159_D0.5851.00
14_I101_V0.5841.00
170_P183_S0.5841.00
180_T183_S0.5831.00
100_L104_V0.5811.00
147_E181_N0.5811.00
111_A130_I0.5791.00
31_V39_A0.5771.00
95_R143_Q0.5761.00
110_F132_Y0.5751.00
19_L24_I0.5751.00
20_T25_P0.5741.00
59_E62_E0.5691.00
66_E102_A0.5661.00
77_R88_A0.5661.00
122_P126_K0.5661.00
96_L150_A0.5641.00
68_A97_L0.5631.00
94_Q98_V0.5611.00
96_L151_F0.5551.00
13_T167_T0.5541.00
125_L128_N0.5531.00
19_L74_V0.5521.00
91_Q94_Q0.5461.00
76_D83_P0.5461.00
148_P151_F0.5451.00
149_Y152_G0.5451.00
141_N144_L0.5441.00
20_T23_D0.5441.00
147_E151_F0.5421.00
22_A82_A0.5421.00
18_M157_L0.5391.00
67_T161_Y0.5391.00
72_L83_P0.5351.00
20_T198_V0.5321.00
92_L151_F0.5301.00
160_C164_T0.5291.00
69_A72_L0.5261.00
99_W139_W0.5251.00
121_A124_Q0.5241.00
18_M74_V0.5221.00
31_V41_R0.5221.00
11_G52_Q0.5201.00
104_V166_R0.5181.00
76_D91_Q0.5161.00
75_L157_L0.5151.00
140_L150_A0.5121.00
12_S28_F0.5101.00
75_L79_P0.5091.00
148_P154_Q0.5051.00
180_T184_A0.5031.00
50_L139_W0.5031.00
7_V32_S0.5011.00
25_P28_F0.5001.00
107_T129_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3gx0A 2 0.9659 100 0.198 Contact Map
4gf0A 2 0.9902 100 0.209 Contact Map
1k0dA 2 0.9805 100 0.209 Contact Map
2x64A 2 0.9805 100 0.219 Contact Map
4l8eA 2 0.9561 100 0.219 Contact Map
3einA 2 0.9707 100 0.226 Contact Map
4ivfA 4 0.9951 100 0.227 Contact Map
1pmtA 2 0.9659 100 0.227 Contact Map
4f0bA 2 0.9756 100 0.227 Contact Map
3uarA 2 0.9707 100 0.228 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0081 seconds.