YNCD - ECOLI - GREMLIN Contacts

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YNCD - Probable TonB-dependent receptor YncD

UniProt:	P76115	Sequences: MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTPAAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIRGIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQQPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQKNLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTIKQTQAGLRYERSLSSRDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQGIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERNLMWNIDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPAGSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNLGLKPSTNDTIEIGSKTRIGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVNASWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEARYMGDIMADDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYEPSPGRNYGVGMNIAWRFE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13774
Length:	700 (611)
Sequences:	54351 (44791)
Seq/√Len:	1812.0

ECOLI - YNCD CIRA FHUA FEPA FHUE FIU BTUB FECA YDDB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
568_W	596_N	4.101	1.00
616_A	636_T	3.809	1.00
196_V	227_V	3.787	1.00
419_Y	445_H	3.606	1.00
233_S	287_R	3.502	1.00
417_V	447_W	3.473	1.00
520_Q	548_Q	3.457	1.00
467_A	499_D	3.452	1.00
461_W	505_S	3.446	1.00
656_F	692_G	3.306	1.00
469_R	499_D	3.203	1.00
611_Y	643_G	3.107	1.00
350_V	403_T	3.059	1.00
204_R	219_N	3.035	1.00
419_Y	447_W	2.955	1.00
236_S	284_R	2.878	1.00
565_N	601_S	2.809	1.00
202_T	219_N	2.755	1.00
461_W	507_T	2.715	1.00
233_S	285_Y	2.701	1.00
355_G	400_Y	2.642	1.00
546_R	576_R	2.544	1.00
241_S	279_T	2.491	1.00
411_L	455_Y	2.447	1.00
234_K	286_E	2.431	1.00
52_G	56_R	2.387	1.00
638_V	663_F	2.380	1.00
520_Q	546_R	2.374	1.00
410_K	455_Y	2.370	1.00
132_N	155_T	2.368	1.00
239_F	279_T	2.344	1.00
507_T	514_L	2.298	1.00
232_A	287_R	2.282	1.00
562_F	602_I	2.246	1.00
570_W	596_N	2.224	1.00
659_V	662_L	2.217	1.00
130_V	154_V	2.217	1.00
616_A	638_V	2.212	1.00
196_V	225_L	2.176	1.00
658_R	690_G	2.155	1.00
618_Y	636_T	2.143	1.00
51_D	54_E	2.143	1.00
167_A	185_G	2.122	1.00
230_D	233_S	2.120	1.00
613_G	641_F	2.095	1.00
356_L	397_I	2.038	1.00
643_G	654_D	2.037	1.00
360_N	395_W	2.032	1.00
614_T	638_V	2.025	1.00
206_T	217_Q	2.023	1.00
243_D	277_K	2.008	1.00
457_M	463_I	2.005	1.00
197_D	226_G	2.004	1.00
515_S	553_A	1.957	1.00
654_D	694_N	1.928	1.00
621_D	631_K	1.899	1.00
454_K	462_N	1.884	1.00
469_R	497_T	1.881	1.00
645_K	654_D	1.846	1.00
467_A	501_I	1.844	1.00
563_R	603_G	1.844	1.00
235_L	285_Y	1.836	1.00
653_V	695_I	1.814	1.00
337_D	357_N	1.807	1.00
411_L	453_L	1.800	1.00
358_Y	397_I	1.776	1.00
63_N	66_E	1.768	1.00
200_V	223_A	1.764	1.00
239_F	281_A	1.761	1.00
561_D	604_Y	1.752	1.00
457_M	461_W	1.743	1.00
518_L	548_Q	1.743	1.00
412_S	456_A	1.728	1.00
421_S	445_H	1.706	1.00
514_L	554_W	1.703	1.00
610_W	644_Y	1.702	1.00
615_E	639_G	1.698	1.00
360_N	393_L	1.697	1.00
350_V	405_W	1.695	1.00
598_G	618_Y	1.682	1.00
226_G	234_K	1.679	1.00
526_E	545_T	1.677	1.00
109_D	224_K	1.671	1.00
297_V	338_S	1.659	1.00
657_G	689_Y	1.651	1.00
562_F	604_Y	1.649	1.00
500_T	521_T	1.647	1.00
203_T	220_L	1.647	1.00
449_P	469_R	1.645	1.00
49_V	134_E	1.641	1.00
653_V	693_M	1.639	1.00
587_G	591_P	1.638	1.00
286_E	294_D	1.635	1.00
161_Q	197_D	1.624	1.00
198_Y	225_L	1.623	1.00
134_E	153_N	1.621	1.00
464_Y	504_G	1.611	1.00
71_V	135_V	1.609	1.00
499_D	524_D	1.607	1.00
292_R	342_H	1.603	1.00
237_L	281_A	1.601	1.00
522_D	544_K	1.593	1.00
286_E	296_S	1.592	1.00
519_F	571_L	1.589	1.00
228_R	234_K	1.588	1.00
530_D	540_K	1.587	1.00
108_V	113_A	1.585	1.00
555_D	565_N	1.583	1.00
226_G	236_S	1.583	1.00
131_Q	157_Q	1.575	1.00
564_V	602_I	1.569	1.00
659_V	689_Y	1.564	1.00
516_L	552_L	1.563	1.00
522_D	546_R	1.561	1.00
458_T	461_W	1.561	1.00
506_K	515_S	1.556	1.00
667_Y	684_S	1.554	1.00
343_R	351_T	1.553	1.00
618_Y	634_S	1.550	1.00
198_Y	202_T	1.550	1.00
456_A	460_A	1.543	1.00
299_M	334_Q	1.538	1.00
295_M	338_S	1.530	1.00
195_D	227_V	1.528	1.00
464_Y	506_K	1.527	1.00
168_S	694_N	1.525	1.00
529_V	539_Y	1.523	1.00
53_E	57_L	1.516	1.00
168_S	180_G	1.515	1.00
297_V	336_I	1.508	1.00
52_G	157_Q	1.506	1.00
494_K	525_D	1.500	1.00
166_E	696_A	1.485	1.00
646_Y	655_L	1.482	1.00
398_D	418_R	1.482	1.00
564_V	600_A	1.482	1.00
90_I	150_G	1.471	1.00
108_V	156_T	1.469	1.00
398_D	420_S	1.465	1.00
406_Q	412_S	1.463	1.00
548_Q	572_D	1.461	1.00
647_N	652_T	1.456	1.00
449_P	453_L	1.438	1.00
640_L	662_L	1.431	1.00
39_S	42_D	1.431	1.00
351_T	404_Q	1.430	1.00
609_G	644_Y	1.430	1.00
293_D	342_H	1.421	1.00
446_K	497_T	1.418	1.00
463_I	505_S	1.416	1.00
452_S	466_A	1.411	1.00
558_F	564_V	1.405	1.00
165_I	183_A	1.404	1.00
497_T	525_D	1.402	1.00
611_Y	645_K	1.401	1.00
519_F	549_G	1.400	1.00
91_R	551_E	1.399	1.00
292_R	344_G	1.396	1.00
641_F	656_F	1.392	1.00
235_L	283_L	1.389	1.00
131_Q	158_T	1.387	1.00
502_E	517_A	1.384	1.00
348_V	405_W	1.383	1.00
200_V	221_A	1.381	1.00
516_L	550_A	1.381	1.00
659_V	687_R	1.381	1.00
601_S	615_E	1.379	1.00
54_E	57_L	1.374	1.00
472_E	496_S	1.368	1.00
301_A	334_Q	1.364	1.00
204_R	217_Q	1.362	1.00
567_S	599_F	1.360	1.00
412_S	454_K	1.360	1.00
510_G	513_L	1.354	1.00
413_L	453_L	1.352	1.00
465_L	501_I	1.350	1.00
653_V	657_G	1.349	1.00
197_D	228_R	1.341	1.00
617_R	639_G	1.340	1.00
603_G	613_G	1.326	1.00
169_S	179_Y	1.326	1.00
544_K	577_S	1.322	1.00
53_E	56_R	1.321	1.00
288_S	294_D	1.320	1.00
566_A	600_A	1.318	1.00
241_S	277_K	1.318	1.00
73_G	569_T	1.317	1.00
234_K	288_S	1.316	1.00
166_E	694_N	1.308	1.00
202_T	221_A	1.304	1.00
402_Q	414_D	1.303	1.00
158_T	226_G	1.299	1.00
238_I	282_G	1.298	1.00
126_D	129_S	1.294	1.00
655_L	693_M	1.294	1.00
351_T	406_Q	1.291	1.00
420_S	448_L	1.289	1.00
229_I	235_L	1.288	1.00
357_N	398_D	1.286	1.00
508_R	512_G	1.283	1.00
356_L	399_P	1.280	1.00
464_Y	517_A	1.277	1.00
611_Y	654_D	1.275	1.00
345_E	349_P	1.271	1.00
158_T	224_K	1.268	1.00
648_Y	652_T	1.268	1.00
596_N	620_G	1.262	1.00
165_I	169_S	1.262	1.00
415_A	451_G	1.261	1.00
338_S	342_H	1.260	1.00
289_L	295_M	1.259	1.00
639_G	660_D	1.259	1.00
109_D	156_T	1.256	1.00
296_S	339_R	1.251	1.00
612_A	642_T	1.250	1.00
91_R	502_E	1.249	1.00
109_D	238_I	1.247	1.00
557_R	563_R	1.240	1.00
232_A	288_S	1.240	1.00
296_S	341_T	1.240	1.00
295_M	340_W	1.239	1.00
198_Y	223_A	1.237	1.00
185_G	198_Y	1.237	1.00
358_Y	395_W	1.236	1.00
610_W	642_T	1.232	1.00
501_I	522_D	1.227	1.00
563_R	605_V	1.225	1.00
461_W	465_L	1.224	1.00
503_I	518_L	1.224	1.00
504_G	517_A	1.220	1.00
349_P	406_Q	1.218	1.00
660_D	688_N	1.207	1.00
518_L	550_A	1.205	1.00
569_T	597_M	1.203	1.00
404_Q	414_D	1.195	1.00
237_L	283_L	1.194	1.00
163_P	167_A	1.192	1.00
221_A	241_S	1.192	1.00
654_D	696_A	1.186	1.00
646_Y	653_V	1.185	1.00
284_R	296_S	1.183	1.00
408_S	411_L	1.183	1.00
66_E	69_T	1.181	1.00
550_A	570_W	1.177	1.00
111_I	300_Y	1.176	1.00
290_S	293_D	1.174	1.00
691_V	695_I	1.174	1.00
410_K	457_M	1.163	1.00
199_T	224_K	1.162	1.00
48_S	137_R	1.161	1.00
643_G	656_F	1.158	1.00
72_P	553_A	1.154	1.00
299_M	336_I	1.151	1.00
528_V	542_A	1.148	1.00
236_S	286_E	1.148	1.00
453_L	457_M	1.147	1.00
58_A	61_R	1.146	1.00
555_D	563_R	1.143	1.00
172_G	176_S	1.143	1.00
465_L	503_I	1.143	1.00
614_T	640_L	1.142	1.00
352_F	403_T	1.133	1.00
501_I	520_Q	1.132	1.00
74_L	90_I	1.131	1.00
547_R	573_A	1.125	1.00
514_L	552_L	1.125	1.00
657_G	691_V	1.117	1.00
243_D	275_T	1.111	1.00
201_S	222_N	1.108	1.00
107_Y	112_P	1.097	1.00
303_E	332_H	1.097	1.00
470_G	498_N	1.095	1.00
602_I	614_T	1.093	1.00
406_Q	409_E	1.091	1.00
472_E	478_E	1.091	1.00
558_F	602_I	1.087	1.00
421_S	443_S	1.087	1.00
619_M	622_I	1.087	1.00
587_G	592_G	1.078	1.00
570_W	595_R	1.077	1.00
638_V	665_K	1.077	1.00
170_Y	692_G	1.076	1.00
603_G	611_Y	1.070	1.00
25_D	28_T	1.068	1.00
349_P	405_W	1.066	1.00
647_N	653_V	1.060	1.00
16_V	19_P	1.058	1.00
131_Q	155_T	1.057	1.00
588_N	591_P	1.055	1.00
58_A	70_G	1.053	1.00
513_L	556_Q	1.051	1.00
75_Q	597_M	1.051	1.00
134_E	155_T	1.051	1.00
605_V	611_Y	1.051	1.00
638_V	662_L	1.050	1.00
509_I	512_G	1.044	1.00
641_F	658_R	1.044	1.00
414_D	452_S	1.044	1.00
561_D	605_V	1.041	1.00
397_I	421_S	1.041	1.00
240_N	280_Q	1.040	1.00
137_R	551_E	1.040	1.00
524_D	544_K	1.039	1.00
284_R	298_M	1.036	1.00
52_G	131_Q	1.036	1.00
617_R	637_L	1.035	1.00
188_G	195_D	1.033	1.00
460_A	507_T	1.032	1.00
163_P	185_G	1.032	1.00
148_S	498_N	1.031	1.00
42_D	456_A	1.030	1.00
339_R	400_Y	1.028	1.00
598_G	620_G	1.026	1.00
181_L	185_G	1.024	1.00
235_L	239_F	1.020	1.00
228_R	231_E	1.018	1.00
498_N	521_T	1.017	1.00
413_L	451_G	1.016	1.00
135_V	152_M	1.016	1.00
514_L	518_L	1.014	1.00
404_Q	412_S	1.012	1.00
457_M	505_S	1.011	1.00
463_I	503_I	1.009	1.00
163_P	183_A	1.009	1.00
71_V	74_L	1.007	1.00
229_I	233_S	1.004	1.00
453_L	465_L	1.002	1.00
49_V	132_N	1.002	1.00
44_P	452_S	1.000	1.00
289_L	340_W	0.995	1.00
637_L	667_Y	0.995	1.00
230_D	287_R	0.993	1.00
642_T	659_V	0.991	1.00
294_D	343_R	0.990	1.00
623_M	631_K	0.988	1.00
107_Y	153_N	0.986	1.00
505_S	516_L	0.986	1.00
448_L	471_F	0.985	1.00
422_V	473_T	0.980	1.00
619_M	635_Y	0.980	1.00
399_P	419_Y	0.978	1.00
544_K	576_R	0.976	1.00
655_L	691_V	0.972	1.00
456_A	462_N	0.969	1.00
129_S	201_S	0.968	1.00
22_F	25_D	0.968	1.00
14_L	17_L	0.966	1.00
519_F	569_T	0.965	1.00
169_S	185_G	0.963	1.00
72_P	567_S	0.959	1.00
656_F	694_N	0.956	1.00
566_A	598_G	0.955	1.00
498_N	523_T	0.954	1.00
224_K	236_S	0.948	1.00
509_I	514_L	0.947	1.00
26_E	29_M	0.947	1.00
229_I	285_Y	0.946	1.00
462_N	506_K	0.945	1.00
645_K	696_A	0.944	1.00
519_F	551_E	0.943	1.00
129_S	222_N	0.940	1.00
55_M	67_S	0.939	1.00
405_W	415_A	0.938	1.00
107_Y	151_V	0.933	1.00
188_G	194_G	0.932	1.00
559_A	562_F	0.932	1.00
126_D	203_T	0.931	1.00
478_E	539_Y	0.931	1.00
15_L	19_P	0.931	1.00
237_L	241_S	0.930	1.00
166_E	182_K	0.930	1.00
416_G	450_A	0.930	1.00
516_L	520_Q	0.928	1.00
300_Y	337_D	0.924	1.00
362_S	391_R	0.923	1.00
512_G	556_Q	0.921	1.00
44_P	454_K	0.919	1.00
129_S	199_T	0.918	1.00
188_G	193_P	0.916	1.00
449_P	467_A	0.915	1.00
350_V	355_G	0.915	1.00
106_L	152_M	0.914	1.00
64_L	154_V	0.914	1.00
144_Y	151_V	0.911	1.00
163_P	198_Y	0.909	1.00
522_D	576_R	0.907	1.00
142_A	416_G	0.906	1.00
195_D	229_I	0.905	1.00
168_S	692_G	0.904	1.00
161_Q	194_G	0.903	1.00
346_L	350_V	0.903	1.00
48_S	553_A	0.903	1.00
195_D	228_R	0.902	1.00
568_W	598_G	0.902	1.00
295_M	299_M	0.901	1.00
407_L	413_L	0.899	1.00
61_R	67_S	0.898	1.00
571_L	593_I	0.898	1.00
294_D	341_T	0.897	1.00
354_T	401_L	0.896	1.00
300_Y	335_G	0.896	1.00
417_V	449_P	0.896	1.00
637_L	684_S	0.895	1.00
337_D	342_H	0.895	1.00
446_K	471_F	0.893	1.00
164_T	696_A	0.891	1.00
278_Q	302_G	0.889	1.00
652_T	695_I	0.886	1.00
19_P	22_F	0.886	1.00
530_D	533_S	0.886	1.00
188_G	196_V	0.886	1.00
111_I	298_M	0.884	1.00
57_L	603_G	0.882	1.00
556_Q	564_V	0.879	1.00
660_D	690_G	0.879	1.00
160_Q	164_T	0.878	1.00
166_E	169_S	0.878	1.00
298_M	337_D	0.877	1.00
587_G	590_M	0.877	1.00
245_K	275_T	0.873	1.00
158_T	236_S	0.872	1.00
501_I	505_S	0.871	1.00
171_Y	177_W	0.871	1.00
105_R	112_P	0.869	1.00
496_S	523_T	0.868	1.00
640_L	659_V	0.864	1.00
46_A	502_E	0.861	1.00
622_I	632_A	0.856	1.00
662_L	687_R	0.855	1.00
620_G	634_S	0.855	1.00
73_G	137_R	0.855	1.00
26_E	30_I	0.853	1.00
655_L	659_V	0.853	1.00
173_S	176_S	0.851	1.00
497_T	524_D	0.847	1.00
664_D	686_G	0.847	1.00
499_D	522_D	0.845	1.00
88_L	152_M	0.843	1.00
631_K	669_G	0.843	1.00
18_S	21_V	0.843	1.00
399_P	403_T	0.842	1.00
589_R	595_R	0.841	1.00
50_V	71_V	0.832	1.00
364_N	391_R	0.831	1.00
288_S	291_S	0.828	1.00
48_S	71_V	0.828	1.00
133_V	154_V	0.826	1.00
460_A	508_R	0.826	1.00
451_G	467_A	0.825	1.00
43_T	47_V	0.825	1.00
550_A	554_W	0.824	1.00
196_V	200_V	0.823	1.00
47_V	134_E	0.823	1.00
399_P	421_S	0.822	1.00
589_R	592_G	0.821	1.00
110_G	153_N	0.818	1.00
396_N	473_T	0.818	1.00
160_Q	184_T	0.817	1.00
605_V	645_K	0.815	1.00
76_V	88_L	0.814	1.00
621_D	634_S	0.813	1.00
652_T	696_A	0.812	1.00
523_T	526_E	0.809	1.00
159_G	226_G	0.809	1.00
598_G	602_I	0.809	1.00
636_T	665_K	0.808	1.00
496_S	526_E	0.807	1.00
164_T	184_T	0.806	1.00
88_L	106_L	0.806	1.00
170_Y	178_R	0.804	1.00
200_V	204_R	0.802	1.00
219_N	243_D	0.802	1.00
633_P	665_K	0.801	1.00
24_A	29_M	0.801	1.00
507_T	510_G	0.801	1.00
163_P	186_A	0.800	1.00
558_F	562_F	0.800	1.00
362_S	393_L	0.799	1.00
552_L	556_Q	0.799	1.00
303_E	330_Q	0.798	1.00
136_L	144_Y	0.793	1.00
612_A	640_L	0.790	1.00
159_G	197_D	0.789	1.00
127_L	130_V	0.788	1.00
91_R	519_F	0.787	1.00
339_R	342_H	0.787	1.00
402_Q	450_A	0.787	1.00
281_A	301_A	0.784	1.00
598_G	636_T	0.783	1.00
609_G	645_K	0.782	1.00
221_A	225_L	0.781	1.00
279_T	283_L	0.779	1.00
219_N	223_A	0.778	1.00
173_S	177_W	0.778	1.00
75_Q	594_A	0.778	1.00
475_T	478_E	0.777	1.00
245_K	273_R	0.775	1.00
448_L	469_R	0.775	1.00
223_A	227_V	0.775	1.00
554_W	566_A	0.775	1.00
414_D	454_K	0.774	1.00
353_T	402_Q	0.771	1.00
561_D	607_E	0.768	1.00
601_S	613_G	0.766	1.00
596_N	618_Y	0.765	1.00
423_W	441_D	0.765	1.00
222_N	240_N	0.765	1.00
105_R	147_A	0.760	1.00
624_A	633_P	0.759	1.00
401_L	417_V	0.759	1.00
111_I	282_G	0.759	1.00
91_R	549_G	0.758	1.00
167_A	171_Y	0.757	1.00
167_A	695_I	0.754	1.00
48_S	72_P	0.753	1.00
553_A	565_N	0.752	1.00
605_V	609_G	0.751	1.00
227_V	230_D	0.751	1.00
444_Y	495_P	0.749	1.00
622_I	633_P	0.746	1.00
89_S	94_G	0.746	1.00
664_D	687_R	0.746	1.00
595_R	620_G	0.745	1.00
136_L	151_V	0.744	1.00
521_T	547_R	0.744	1.00
143_L	353_T	0.744	1.00
205_F	218_K	0.743	1.00
90_I	135_V	0.743	1.00
293_D	354_T	0.743	1.00
285_Y	297_V	0.741	1.00
456_A	459_D	0.740	1.00
546_R	574_T	0.740	1.00
52_G	55_M	0.740	1.00
604_Y	607_E	0.740	1.00
289_L	293_D	0.739	1.00
645_K	652_T	0.738	1.00
106_L	122_T	0.738	1.00
169_S	177_W	0.737	1.00
24_A	27_Q	0.737	1.00
62_I	66_E	0.735	1.00
459_D	508_R	0.734	1.00
352_F	401_L	0.733	1.00
182_K	199_T	0.731	1.00
64_L	67_S	0.731	1.00
161_Q	228_R	0.730	1.00
565_N	603_G	0.727	1.00
563_R	566_A	0.727	1.00
571_L	575_Y	0.726	1.00
196_V	229_I	0.724	1.00
551_E	569_T	0.723	1.00
422_V	444_Y	0.721	1.00
509_I	513_L	0.721	1.00
183_A	186_A	0.721	1.00
352_F	356_L	0.721	1.00
174_F	177_W	0.719	1.00
197_D	234_K	0.719	1.00
244_I	276_I	0.718	1.00
672_I	675_E	0.717	1.00
93_F	149_G	0.717	1.00
17_L	20_V	0.717	1.00
458_T	507_T	0.716	1.00
199_T	222_N	0.716	1.00
554_W	558_F	0.716	1.00
564_V	568_W	0.716	1.00
644_Y	647_N	0.715	1.00
121_Q	124_N	0.714	1.00
407_L	453_L	0.714	1.00
449_P	452_S	0.712	1.00
475_T	493_L	0.712	1.00
685_P	688_N	0.712	1.00
611_Y	614_T	0.712	1.00
335_G	339_R	0.712	1.00
69_T	617_R	0.711	1.00
46_A	517_A	0.711	1.00
57_L	611_Y	0.710	1.00
354_T	358_Y	0.709	1.00
523_T	545_T	0.708	1.00
545_T	590_M	0.708	1.00
301_A	332_H	0.707	1.00
40_E	49_V	0.706	1.00
572_D	595_R	0.703	1.00
336_I	340_W	0.702	1.00
410_K	456_A	0.702	1.00
571_L	577_S	0.701	1.00
128_S	168_S	0.699	1.00
547_R	571_L	0.697	1.00
232_A	289_L	0.696	1.00
128_S	166_E	0.696	1.00
298_M	339_R	0.693	1.00
658_R	692_G	0.693	1.00
338_S	356_L	0.691	1.00
342_H	352_F	0.691	1.00
279_T	303_E	0.691	1.00
513_L	558_F	0.689	1.00
309_Y	326_V	0.689	1.00
403_T	415_A	0.688	1.00
608_D	644_Y	0.684	1.00
475_T	479_L	0.683	1.00
396_N	422_V	0.683	1.00
595_R	621_D	0.683	1.00
561_D	564_V	0.682	1.00
441_D	444_Y	0.681	1.00
638_V	659_V	0.680	1.00
105_R	151_V	0.679	1.00
137_R	553_A	0.679	1.00
623_M	632_A	0.678	1.00
159_G	198_Y	0.675	1.00
357_N	400_Y	0.674	1.00
446_K	469_R	0.673	1.00
336_I	339_R	0.673	1.00
450_A	466_A	0.672	1.00
604_Y	612_A	0.672	1.00
464_Y	515_S	0.672	1.00
334_Q	337_D	0.672	1.00
343_R	349_P	0.671	1.00
334_Q	338_S	0.671	1.00
217_Q	245_K	0.670	1.00
138_G	502_E	0.670	1.00
171_Y	175_G	0.670	1.00
206_T	219_N	0.670	1.00
503_I	507_T	0.668	1.00
196_V	223_A	0.668	1.00
139_P	468_G	0.667	1.00
287_R	290_S	0.667	1.00
353_T	404_Q	0.666	1.00
282_G	300_Y	0.664	1.00
61_R	66_E	0.664	1.00
446_K	495_P	0.663	1.00
226_G	229_I	0.661	1.00
93_F	523_T	0.660	1.00
335_G	359_E	0.660	1.00
54_E	58_A	0.659	1.00
236_S	296_S	0.659	1.00
170_Y	690_G	0.658	1.00
663_F	666_E	0.657	1.00
216_A	244_I	0.657	1.00
654_D	657_G	0.656	1.00
293_D	340_W	0.656	1.00
224_K	238_I	0.656	1.00
412_S	415_A	0.655	1.00
56_R	694_N	0.654	1.00
209_G	214_S	0.654	1.00
338_S	341_T	0.653	1.00
493_L	527_I	0.652	1.00
527_I	539_Y	0.652	1.00
24_A	28_T	0.652	1.00
361_M	394_M	0.650	1.00
573_A	593_I	0.650	1.00
131_Q	160_Q	0.650	1.00
607_E	610_W	0.650	1.00
128_S	180_G	0.649	1.00
339_R	353_T	0.648	1.00
305_E	330_Q	0.647	1.00
600_A	636_T	0.646	1.00
14_L	19_P	0.645	1.00
210_Y	686_G	0.643	1.00
136_L	140_F	0.642	1.00
597_M	619_M	0.642	1.00
415_A	419_Y	0.642	1.00
588_N	592_G	0.641	1.00
254_K	265_P	0.640	1.00
413_L	417_V	0.640	1.00
527_I	541_N	0.639	1.00
564_V	575_Y	0.637	1.00
165_I	181_L	0.637	1.00
291_S	344_G	0.636	1.00
27_Q	30_I	0.635	1.00
402_Q	416_G	0.635	1.00
41_L	508_R	0.634	1.00
552_L	568_W	0.634	1.00
182_K	186_A	0.633	1.00
466_A	502_E	0.632	1.00
350_V	354_T	0.632	1.00
93_F	97_S	0.632	1.00
162_P	165_I	0.631	1.00
159_G	199_T	0.631	1.00
574_T	587_G	0.630	1.00
179_Y	183_A	0.630	1.00
106_L	154_V	0.630	1.00
513_L	557_R	0.629	1.00
64_L	130_V	0.629	1.00
359_E	396_N	0.629	1.00
337_D	341_T	0.629	1.00
510_G	556_Q	0.628	1.00
636_T	663_F	0.628	1.00
379_E	382_Q	0.628	1.00
139_P	470_G	0.627	1.00
365_R	390_E	0.626	1.00
72_P	137_R	0.626	1.00
490_N	540_K	0.626	1.00
163_P	166_E	0.626	1.00
233_S	237_L	0.626	1.00
67_S	127_L	0.625	1.00
553_A	567_S	0.625	1.00
171_Y	181_L	0.625	1.00
183_A	187_T	0.625	1.00
170_Y	656_F	0.624	1.00
347_G	350_V	0.624	1.00
344_G	352_F	0.624	1.00
176_S	207_T	0.623	1.00
93_F	547_R	0.622	1.00
215_G	247_D	0.622	1.00
287_R	295_M	0.621	1.00
175_G	208_H	0.621	1.00
556_Q	559_A	0.620	1.00
158_T	238_I	0.616	1.00
394_M	473_T	0.615	1.00
158_T	234_K	0.615	1.00
174_F	688_N	0.615	1.00
571_L	597_M	0.615	1.00
74_L	88_L	0.614	1.00
476_I	479_L	0.613	1.00
32_S	35_P	0.612	1.00
693_M	697_W	0.612	1.00
195_D	230_D	0.612	1.00
44_P	414_D	0.611	1.00
689_Y	693_M	0.611	1.00
625_D	629_T	0.610	1.00
293_D	352_F	0.610	1.00
285_Y	289_L	0.609	1.00
400_Y	418_R	0.609	1.00
348_V	355_G	0.609	1.00
505_S	514_L	0.608	1.00
179_Y	204_R	0.608	1.00
292_R	343_R	0.606	1.00
163_P	169_S	0.604	1.00
614_T	662_L	0.604	1.00
21_V	24_A	0.603	1.00
609_G	647_N	0.603	1.00
691_V	694_N	0.603	1.00
173_S	689_Y	0.603	1.00
142_A	402_Q	0.602	1.00
93_F	521_T	0.602	1.00
557_R	561_D	0.602	1.00
142_A	450_A	0.602	1.00
336_I	342_H	0.602	1.00
307_T	328_T	0.599	1.00
336_I	358_Y	0.599	1.00
15_L	18_S	0.599	1.00
211_R	214_S	0.598	1.00
457_M	460_A	0.598	1.00
494_K	497_T	0.598	1.00
14_L	18_S	0.597	1.00
442_A	492_G	0.597	1.00
66_E	660_D	0.596	1.00
562_F	570_W	0.596	1.00
333_Y	361_M	0.595	1.00
564_V	567_S	0.595	1.00
57_L	605_V	0.595	1.00
525_D	541_N	0.595	1.00
588_N	623_M	0.594	1.00
350_V	353_T	0.594	1.00
289_L	292_R	0.593	1.00
460_A	509_I	0.593	1.00
177_W	206_T	0.592	1.00
616_A	663_F	0.591	1.00
405_W	413_L	0.590	1.00
562_F	566_A	0.590	1.00
600_A	616_A	0.589	1.00
218_K	244_I	0.588	1.00
566_A	570_W	0.587	1.00
395_W	423_W	0.585	1.00
502_E	551_E	0.583	1.00
193_P	196_V	0.582	1.00
415_A	453_L	0.582	1.00
640_L	657_G	0.581	1.00
451_G	455_Y	0.581	1.00
406_Q	456_A	0.581	1.00
351_T	354_T	0.579	1.00
609_G	646_Y	0.578	1.00
465_L	505_S	0.578	1.00
277_K	305_E	0.577	1.00
620_G	636_T	0.575	1.00
46_A	137_R	0.575	1.00
348_V	357_N	0.574	1.00
557_R	560_G	0.573	1.00
496_S	525_D	0.573	1.00
646_Y	652_T	0.572	1.00
195_D	231_E	0.571	1.00
143_L	400_Y	0.571	1.00
470_G	500_T	0.570	1.00
397_I	423_W	0.569	1.00
172_G	177_W	0.569	1.00
174_F	178_R	0.569	1.00
594_A	619_M	0.568	1.00
578_N	586_N	0.568	1.00
122_T	154_V	0.568	1.00
558_F	561_D	0.566	1.00
493_L	541_N	0.566	1.00
612_A	616_A	0.566	1.00
41_L	456_A	0.566	1.00
157_Q	199_T	0.566	1.00
41_L	462_N	0.565	1.00
321_S	324_G	0.565	1.00
471_F	497_T	0.564	1.00
642_T	646_Y	0.564	1.00
399_P	445_H	0.562	1.00
526_E	547_R	0.562	1.00
20_V	23_A	0.561	1.00
344_G	350_V	0.561	1.00
307_T	326_V	0.560	1.00
367_G	388_R	0.560	1.00
504_G	515_S	0.559	1.00
297_V	301_A	0.559	1.00
54_E	565_N	0.559	1.00
450_A	468_G	0.558	1.00
70_G	615_E	0.557	1.00
350_V	357_N	0.557	1.00
172_G	690_G	0.556	1.00
501_I	518_L	0.556	1.00
599_F	615_E	0.555	1.00
155_T	158_T	0.555	1.00
499_D	520_Q	0.554	1.00
342_H	345_E	0.553	1.00
471_F	495_P	0.552	1.00
107_Y	144_Y	0.552	1.00
72_P	75_Q	0.552	1.00
160_Q	197_D	0.551	1.00
349_P	408_S	0.550	1.00
529_V	537_T	0.550	1.00
642_T	657_G	0.548	1.00
233_S	289_L	0.547	1.00
77_Q	87_Q	0.546	1.00
589_R	623_M	0.545	1.00
232_A	290_S	0.544	1.00
67_S	71_V	0.543	1.00
148_S	472_E	0.542	1.00
342_H	354_T	0.542	1.00
548_Q	570_W	0.542	1.00
34_A	37_V	0.542	1.00
297_V	334_Q	0.541	1.00
610_W	614_T	0.540	1.00
597_M	617_R	0.539	1.00
128_S	201_S	0.536	1.00
421_S	444_Y	0.536	1.00
546_R	572_D	0.536	1.00
423_W	443_S	0.536	1.00
348_V	352_F	0.536	1.00
461_W	509_I	0.535	1.00
602_I	612_A	0.535	1.00
523_T	547_R	0.534	1.00
69_T	639_G	0.533	1.00
405_W	408_S	0.533	1.00
502_E	506_K	0.533	1.00
174_F	207_T	0.532	1.00
44_P	47_V	0.532	1.00
45_A	450_A	0.532	1.00
394_M	422_V	0.532	1.00
513_L	554_W	0.531	1.00
129_S	220_L	0.530	1.00
207_T	216_A	0.529	1.00
451_G	454_K	0.528	1.00
573_A	590_M	0.527	1.00
410_K	458_T	0.526	1.00
148_S	470_G	0.526	1.00
556_Q	602_I	0.526	1.00
181_L	186_A	0.524	1.00
466_A	500_T	0.524	1.00
183_A	198_Y	0.524	1.00
633_P	668_V	0.523	1.00
182_K	201_S	0.523	1.00
282_G	298_M	0.523	1.00
507_T	512_G	0.522	1.00
170_Y	658_R	0.522	1.00
339_R	357_N	0.522	1.00
136_L	141_S	0.521	1.00
646_Y	693_M	0.521	1.00
507_T	515_S	0.521	1.00
645_K	648_Y	0.520	1.00
624_A	632_A	0.520	1.00
113_A	280_Q	0.520	1.00
222_N	238_I	0.520	1.00
451_G	465_L	0.520	1.00
564_V	577_S	0.519	1.00
61_R	70_G	0.519	1.00
350_V	406_Q	0.519	1.00
509_I	554_W	0.517	1.00
461_W	514_L	0.517	1.00
556_Q	566_A	0.517	1.00
407_L	411_L	0.517	1.00
335_G	338_S	0.516	1.00
25_D	29_M	0.516	1.00
607_E	612_A	0.516	1.00
223_A	226_G	0.515	1.00
653_V	691_V	0.515	1.00
182_K	185_G	0.515	1.00
225_L	237_L	0.514	1.00
293_D	344_G	0.514	1.00
638_V	642_T	0.514	1.00
575_Y	578_N	0.514	1.00
341_T	351_T	0.513	1.00
39_S	43_T	0.511	1.00
545_T	573_A	0.511	1.00
111_I	238_I	0.510	1.00
459_D	512_G	0.510	1.00
637_L	664_D	0.509	1.00
266_R	269_Q	0.509	1.00
531_S	537_T	0.509	1.00
281_A	285_Y	0.509	1.00
624_A	630_A	0.507	1.00
42_D	406_Q	0.507	1.00
526_E	543_G	0.507	1.00
508_R	513_L	0.506	1.00
641_F	654_D	0.506	1.00
641_F	690_G	0.505	1.00
564_V	571_L	0.504	1.00
147_A	150_G	0.503	1.00
341_T	344_G	0.503	1.00
107_Y	155_T	0.503	1.00
455_Y	458_T	0.502	1.00
40_E	47_V	0.502	1.00
599_F	617_R	0.502	1.00
171_Y	691_V	0.502	1.00
229_I	232_A	0.500	1.00
555_D	558_F	0.500	1.00
564_V	569_T	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qlbA	1	0.89	100	0.216	Contact Map
3efmA	1	0.79	100	0.219	Contact Map
1xkwA	1	0.8914	100	0.221	Contact Map
1kmoA	1	0.8957	100	0.231	Contact Map
3v8xA	1	0.8943	100	0.237	Contact Map
4cu4A	1	0.9229	100	0.239	Contact Map
2w16A	1	0.9257	100	0.24	Contact Map
2hdiA	1	0.7843	100	0.251	Contact Map
2gufA	1	0.7743	100	0.253	Contact Map
3fhhA	1	0.8314	100	0.271	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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