YDCP - ECOLI - GREMLIN Contacts

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YDCP - Uncharacterized protease YdcP

UniProt:	P76104	Sequences: MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNASNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMGILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLDQIRAIHQATDATIEFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLSMKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARASSGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVVKVAKDHLDVAVTEPLANGDGLNVLIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNRNLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNAEKAMNNLKDGLAKLGQTLYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLASYQRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPVMITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKNHILKMPLPGSVVASVSPDELLKTLPKRKG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13759
Length:	653 (542)
Sequences:	975 (750)
Seq/√Len:	32.2

ECOLI - YDCP
BACSU - YRRO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
469_Y	501_D	5.694	1.00
428_L	496_A	5.186	1.00
430_S	504_R	4.494	1.00
414_D	472_R	4.377	1.00
104_L	135_F	4.303	1.00
464_L	497_A	4.224	1.00
81_A	103_I	3.911	1.00
259_R	263_D	3.896	1.00
415_I	428_L	3.891	1.00
454_M	458_K	3.795	1.00
12_S	255_T	3.740	1.00
334_V	390_L	3.652	1.00
67_V	88_L	3.597	1.00
202_L	216_L	3.508	1.00
24_I	63_A	3.492	1.00
10_L	262_L	3.481	1.00
137_Q	159_T	3.359	1.00
463_K	490_N	3.192	1.00
345_G	356_G	3.062	1.00
55_V	93_V	3.011	1.00
427_T	437_T	2.995	1.00
464_L	471_A	2.975	1.00
232_I	239_F	2.872	1.00
85_I	103_I	2.740	1.00
150_R	154_Q	2.739	1.00
131_S	157_D	2.697	1.00
35_G	84_L	2.658	1.00
471_A	474_V	2.652	1.00
231_L	239_F	2.646	1.00
415_I	426_L	2.585	1.00
162_F	231_L	2.535	1.00
69_L	85_I	2.519	1.00
153_H	160_I	2.455	0.99
372_V	375_N	2.439	0.99
26_H	405_T	2.421	0.99
491_Q	495_E	2.421	0.99
415_I	496_A	2.401	0.99
396_H	400_Q	2.395	0.99
160_I	236_V	2.372	0.99
414_D	473_D	2.359	0.99
416_E	475_Q	2.352	0.99
228_L	262_L	2.324	0.99
26_H	252_K	2.282	0.99
39_G	71_T	2.246	0.99
369_Q	372_V	2.175	0.99
229_G	268_E	2.175	0.99
55_V	91_T	2.147	0.99
96_L	111_I	2.104	0.98
425_I	437_T	2.090	0.98
47_S	50_D	2.086	0.98
121_I	127_A	2.065	0.98
286_P	338_E	2.046	0.98
458_K	462_A	2.045	0.98
415_I	471_A	2.026	0.98
426_L	461_L	2.022	0.98
86_T	108_I	2.008	0.98
430_S	434_V	2.000	0.98
417_L	424_L	1.998	0.98
67_V	93_V	1.964	0.97
232_I	262_L	1.955	0.97
88_L	93_V	1.948	0.97
253_N	402_L	1.946	0.97
233_D	269_R	1.934	0.97
138_I	158_A	1.924	0.97
69_L	81_A	1.905	0.97
498_D	502_A	1.904	0.97
416_E	427_T	1.899	0.97
418_G	477_N	1.893	0.97
8_L	232_I	1.884	0.97
225_T	257_H	1.881	0.97
225_T	261_M	1.867	0.96
540_R	544_H	1.863	0.96
121_I	130_L	1.852	0.96
426_L	492_F	1.842	0.96
20_A	54_L	1.836	0.96
418_G	425_I	1.824	0.96
410_R	466_Q	1.823	0.96
127_A	138_I	1.820	0.96
234_A	239_F	1.815	0.96
417_L	426_L	1.813	0.96
232_I	265_I	1.798	0.96
17_A	53_E	1.797	0.96
445_D	448_N	1.796	0.96
239_F	262_L	1.791	0.95
428_L	497_A	1.755	0.95
127_A	152_I	1.749	0.95
434_V	504_R	1.747	0.95
37_G	80_P	1.747	0.95
345_G	393_N	1.743	0.95
228_L	265_I	1.735	0.95
369_Q	375_N	1.715	0.94
460_G	490_N	1.713	0.94
24_I	57_F	1.707	0.94
33_I	65_I	1.695	0.94
444_F	482_L	1.676	0.93
198_L	215_H	1.671	0.93
25_L	57_F	1.627	0.92
464_L	467_T	1.625	0.92
446_E	481_A	1.609	0.92
341_A	397_N	1.598	0.92
323_E	389_P	1.592	0.92
81_A	85_I	1.590	0.92
58_A	65_I	1.580	0.91
48_L	87_D	1.565	0.91
147_D	150_R	1.564	0.91
10_L	254_I	1.556	0.91
39_G	42_H	1.553	0.91
253_N	291_T	1.552	0.91
324_V	348_V	1.532	0.90
178_I	182_Q	1.526	0.90
128_K	131_S	1.522	0.90
356_G	393_N	1.522	0.90
20_A	31_V	1.513	0.89
224_Q	227_N	1.513	0.89
65_I	145_N	1.510	0.89
183_T	193_S	1.508	0.89
113_L	135_F	1.495	0.89
162_F	301_V	1.494	0.89
254_I	288_T	1.490	0.89
320_P	389_P	1.480	0.88
204_D	208_R	1.478	0.88
356_G	360_N	1.470	0.88
262_L	265_I	1.470	0.88
10_L	259_R	1.465	0.88
162_F	236_V	1.464	0.88
315_K	345_G	1.455	0.87
429_T	435_S	1.454	0.87
356_G	359_A	1.448	0.87
195_A	200_Y	1.446	0.87
420_W	479_P	1.437	0.87
67_V	91_T	1.435	0.87
427_T	435_S	1.435	0.87
230_A	302_N	1.430	0.86
153_H	236_V	1.403	0.85
150_R	233_D	1.392	0.85
153_H	157_D	1.390	0.85
127_A	158_A	1.386	0.85
227_N	298_D	1.375	0.84
120_D	141_A	1.375	0.84
416_E	477_N	1.374	0.84
256_A	260_Q	1.371	0.84
462_A	471_A	1.365	0.84
178_I	200_Y	1.363	0.84
144_L	152_I	1.354	0.83
124_V	155_A	1.339	0.83
460_G	463_K	1.339	0.83
21_R	25_L	1.337	0.82
498_D	501_D	1.337	0.82
98_V	103_I	1.335	0.82
95_A	114_H	1.334	0.82
419_G	444_F	1.334	0.82
78_L	106_L	1.320	0.82
34_G	39_G	1.317	0.81
73_L	81_A	1.315	0.81
419_G	424_L	1.311	0.81
214_K	312_D	1.307	0.81
130_L	135_F	1.303	0.81
241_I	255_T	1.293	0.80
223_D	296_S	1.292	0.80
151_A	155_A	1.290	0.80
261_M	264_A	1.287	0.80
488_L	491_Q	1.286	0.80
293_H	296_S	1.285	0.80
24_I	58_A	1.285	0.80
18_A	551_I	1.278	0.79
69_L	84_L	1.276	0.79
89_Y	108_I	1.272	0.79
345_G	358_R	1.265	0.79
328_A	331_H	1.264	0.79
89_Y	109_P	1.259	0.78
417_L	461_L	1.258	0.78
236_V	239_F	1.256	0.78
178_I	195_A	1.256	0.78
127_A	160_I	1.255	0.78
82_Q	98_V	1.250	0.78
415_I	474_V	1.246	0.78
71_T	115_A	1.242	0.77
455_N	458_K	1.238	0.77
227_N	302_N	1.234	0.77
260_Q	284_F	1.226	0.77
229_G	265_I	1.226	0.77
16_D	45_S	1.225	0.76
356_G	369_Q	1.224	0.76
131_S	156_T	1.220	0.76
460_G	489_L	1.219	0.76
121_I	126_K	1.214	0.76
36_P	50_D	1.214	0.76
222_N	297_T	1.209	0.76
26_H	392_R	1.205	0.75
131_S	158_A	1.201	0.75
16_D	19_I	1.196	0.75
455_N	459_D	1.196	0.75
19_I	248_M	1.195	0.75
306_G	309_G	1.190	0.74
79_E	82_Q	1.183	0.74
43_N	245_Y	1.182	0.74
359_A	362_V	1.180	0.74
60_R	501_D	1.176	0.73
370_Y	375_N	1.164	0.73
247_D	395_D	1.150	0.72
9_E	238_S	1.144	0.71
8_L	266_I	1.143	0.71
539_A	542_F	1.140	0.71
415_I	461_L	1.139	0.71
313_S	347_N	1.134	0.71
410_R	470_Y	1.124	0.70
105_E	545_R	1.122	0.70
10_L	263_D	1.121	0.70
364_K	367_E	1.121	0.70
120_D	175_Q	1.118	0.70
346_L	359_A	1.113	0.69
164_I	261_M	1.113	0.69
372_V	376_E	1.112	0.69
321_V	337_T	1.110	0.69
20_A	58_A	1.108	0.69
39_G	43_N	1.106	0.69
22_E	25_L	1.100	0.68
82_Q	106_L	1.100	0.68
227_N	230_A	1.096	0.68
366_G	369_Q	1.094	0.68
342_N	362_V	1.091	0.68
405_T	408_E	1.089	0.68
73_L	103_I	1.086	0.67
531_L	550_L	1.083	0.67
153_H	237_R	1.083	0.67
299_Y	308_I	1.079	0.67
334_V	357_F	1.078	0.67
411_V	504_R	1.078	0.67
425_I	439_T	1.076	0.67
417_L	476_I	1.076	0.67
98_V	102_G	1.075	0.67
153_H	156_T	1.074	0.66
536_N	539_A	1.071	0.66
82_Q	86_T	1.070	0.66
178_I	183_T	1.068	0.66
424_L	444_F	1.067	0.66
219_M	309_G	1.065	0.66
187_A	195_A	1.064	0.66
392_R	483_F	1.063	0.66
392_R	395_D	1.062	0.66
180_H	195_A	1.058	0.65
171_A	300_F	1.054	0.65
87_D	90_Q	1.053	0.65
112_E	159_T	1.053	0.65
102_G	109_P	1.048	0.64
97_I	129_F	1.037	0.64
150_R	234_A	1.036	0.64
26_H	256_A	1.034	0.63
412_A	470_Y	1.034	0.63
165_H	258_Y	1.031	0.63
438_H	499_M	1.031	0.63
85_I	96_L	1.029	0.63
421_Q	482_L	1.025	0.63
21_R	53_E	1.019	0.62
436_I	500_L	1.017	0.62
452_K	484_V	1.014	0.62
413_V	428_L	1.006	0.61
436_I	496_A	1.005	0.61
350_I	355_V	1.003	0.61
417_L	457_L	1.002	0.61
102_G	498_D	1.000	0.61
534_V	540_R	0.999	0.61
33_I	67_V	0.991	0.60
261_M	284_F	0.985	0.60
426_L	438_H	0.983	0.59
148_Q	487_S	0.980	0.59
297_T	300_F	0.975	0.59
33_I	58_A	0.973	0.59
93_V	111_I	0.971	0.59
373_W	376_E	0.970	0.58
89_Y	110_P	0.970	0.58
394_L	399_Q	0.969	0.58
321_V	346_L	0.968	0.58
436_I	503_A	0.963	0.58
183_T	200_Y	0.960	0.58
320_P	337_T	0.960	0.58
71_T	149_I	0.956	0.57
9_E	30_A	0.955	0.57
370_Y	376_E	0.954	0.57
414_D	429_T	0.953	0.57
220_K	295_G	0.941	0.56
290_K	395_D	0.941	0.56
35_G	187_A	0.939	0.56
457_L	489_L	0.935	0.56
268_E	271_D	0.930	0.55
22_E	248_M	0.930	0.55
467_T	497_A	0.928	0.55
419_G	478_L	0.925	0.55
48_L	84_L	0.925	0.55
14_A	46_N	0.923	0.55
543_Y	547_G	0.923	0.55
412_A	472_R	0.920	0.54
114_H	139_V	0.920	0.54
172_Y	460_G	0.919	0.54
88_L	91_T	0.917	0.54
180_H	187_A	0.915	0.54
365_T	369_Q	0.914	0.54
400_Q	404_K	0.910	0.54
42_H	191_D	0.909	0.53
48_L	91_T	0.907	0.53
469_Y	504_R	0.905	0.53
290_K	319_L	0.900	0.53
51_I	103_I	0.900	0.53
112_E	136_T	0.899	0.53
438_H	496_A	0.899	0.53
475_Q	502_A	0.896	0.52
56_P	509_Q	0.895	0.52
229_G	233_D	0.892	0.52
35_G	490_N	0.890	0.52
228_L	422_E	0.889	0.52
87_D	91_T	0.889	0.52
491_Q	494_R	0.888	0.52
219_M	308_I	0.888	0.52
325_V	335_A	0.886	0.52
324_V	332_L	0.883	0.51
451_E	481_A	0.881	0.51
233_D	265_I	0.881	0.51
486_N	490_N	0.879	0.51
52_A	91_T	0.878	0.51
120_D	469_Y	0.877	0.51
347_N	354_V	0.876	0.51
503_A	506_A	0.875	0.51
77_E	189_R	0.874	0.51
440_L	492_F	0.874	0.51
8_L	199_P	0.871	0.50
146_L	230_A	0.868	0.50
326_K	333_D	0.867	0.50
422_E	495_E	0.866	0.50
84_L	187_A	0.866	0.50
434_V	503_A	0.862	0.50
228_L	371_R	0.862	0.50
298_D	302_N	0.860	0.49
64_K	128_K	0.858	0.49
249_S	399_Q	0.858	0.49
79_E	267_E	0.858	0.49
10_L	292_F	0.857	0.49
183_T	195_A	0.856	0.49
128_K	132_D	0.855	0.49
35_G	71_T	0.854	0.49
224_Q	300_F	0.854	0.49
315_K	347_N	0.853	0.49
98_V	469_Y	0.851	0.49
59_H	94_D	0.849	0.49
419_G	479_P	0.847	0.48
247_D	392_R	0.843	0.48
39_G	68_T	0.841	0.48
364_K	369_Q	0.840	0.48
370_Y	373_W	0.839	0.48
17_A	21_R	0.837	0.48
202_L	217_L	0.836	0.47
369_Q	376_E	0.836	0.47
450_A	456_N	0.829	0.47
123_T	157_D	0.828	0.47
140_L	162_F	0.827	0.47
98_V	104_L	0.825	0.47
50_D	437_T	0.824	0.46
137_Q	237_R	0.824	0.46
300_F	308_I	0.823	0.46
207_G	210_V	0.822	0.46
321_V	421_Q	0.821	0.46
489_L	492_F	0.821	0.46
236_V	301_V	0.821	0.46
127_A	238_S	0.820	0.46
369_Q	374_P	0.818	0.46
81_A	97_I	0.814	0.46
149_I	231_L	0.812	0.46
216_L	460_G	0.809	0.45
539_A	543_Y	0.807	0.45
334_V	372_V	0.807	0.45
336_V	340_L	0.805	0.45
25_L	61_Y	0.802	0.45
384_I	390_L	0.800	0.45
36_P	73_L	0.799	0.44
325_V	333_D	0.799	0.44
9_E	13_P	0.798	0.44
138_I	460_G	0.795	0.44
191_D	245_Y	0.791	0.44
461_L	496_A	0.790	0.44
489_L	505_L	0.789	0.44
424_L	492_F	0.783	0.43
57_F	61_Y	0.782	0.43
84_L	88_L	0.780	0.43
89_Y	510_R	0.776	0.43
321_V	392_R	0.776	0.43
35_G	316_F	0.776	0.43
221_D	343_G	0.774	0.42
454_M	480_G	0.774	0.42
499_M	502_A	0.774	0.42
440_L	488_L	0.773	0.42
74_H	180_H	0.772	0.42
182_Q	195_A	0.771	0.42
140_L	292_F	0.770	0.42
350_I	354_V	0.768	0.42
400_Q	403_T	0.765	0.42
25_L	97_I	0.764	0.42
36_P	187_A	0.763	0.42
290_K	392_R	0.762	0.41
247_D	399_Q	0.760	0.41
415_I	464_L	0.751	0.41
87_D	392_R	0.750	0.41
305_K	308_I	0.750	0.41
162_F	492_F	0.749	0.40
90_Q	510_R	0.749	0.40
290_K	398_W	0.748	0.40
146_L	301_V	0.747	0.40
468_L	501_D	0.747	0.40
418_G	427_T	0.745	0.40
410_R	468_L	0.745	0.40
224_Q	301_V	0.744	0.40
182_Q	316_F	0.744	0.40
64_K	136_T	0.743	0.40
66_F	468_L	0.742	0.40
365_T	372_V	0.741	0.40
454_M	475_Q	0.741	0.40
21_R	57_F	0.741	0.40
69_L	296_S	0.738	0.40
26_H	248_M	0.738	0.40
326_K	386_P	0.738	0.40
319_L	398_W	0.738	0.40
74_H	535_Y	0.738	0.40
219_M	390_L	0.736	0.39
413_V	500_L	0.734	0.39
270_G	426_L	0.732	0.39
328_A	473_D	0.731	0.39
154_Q	231_L	0.731	0.39
37_G	511_G	0.730	0.39
43_N	191_D	0.730	0.39
226_A	285_V	0.730	0.39
82_Q	103_I	0.727	0.39
292_F	345_G	0.726	0.39
151_A	154_Q	0.724	0.38
7_R	29_D	0.721	0.38
52_A	87_D	0.718	0.38
101_M	130_L	0.718	0.38
231_L	235_G	0.717	0.38
198_L	263_D	0.716	0.38
104_L	113_L	0.715	0.38
131_S	153_H	0.714	0.38
257_H	288_T	0.714	0.38
132_D	445_D	0.712	0.38
534_V	539_A	0.711	0.37
337_T	390_L	0.711	0.37
35_G	39_G	0.710	0.37
345_G	394_L	0.708	0.37
499_M	503_A	0.704	0.37
124_V	152_I	0.703	0.37
55_V	67_V	0.702	0.37
548_V	551_I	0.702	0.37
121_I	141_A	0.700	0.37
144_L	148_Q	0.700	0.37
490_N	494_R	0.699	0.37
479_P	482_L	0.698	0.36
323_E	335_A	0.697	0.36
182_Q	200_Y	0.696	0.36
224_Q	245_Y	0.694	0.36
533_N	536_N	0.693	0.36
231_L	234_A	0.693	0.36
463_K	483_F	0.692	0.36
239_F	266_I	0.690	0.36
194_Q	219_M	0.689	0.36
422_E	441_D	0.689	0.36
73_L	78_L	0.689	0.36
322_G	337_T	0.686	0.36
201_T	213_E	0.685	0.35
438_H	492_F	0.685	0.35
541_E	545_R	0.684	0.35
374_P	377_M	0.684	0.35
46_N	68_T	0.682	0.35
443_Q	505_L	0.682	0.35
51_I	91_T	0.682	0.35
133_V	510_R	0.681	0.35
62_G	172_Y	0.681	0.35
71_T	141_A	0.681	0.35
426_L	496_A	0.677	0.35
29_D	263_D	0.677	0.35
453_A	459_D	0.677	0.35
260_Q	281_E	0.676	0.35
180_H	245_Y	0.675	0.35
264_A	284_F	0.675	0.35
102_G	106_L	0.675	0.35
446_E	458_K	0.675	0.35
473_D	514_K	0.673	0.35
539_A	554_A	0.672	0.35
96_L	113_L	0.670	0.34
111_I	260_Q	0.668	0.34
360_N	363_E	0.668	0.34
485_P	488_L	0.667	0.34
450_A	453_A	0.667	0.34
31_V	340_L	0.666	0.34
223_D	254_I	0.666	0.34
167_A	194_Q	0.665	0.34
171_A	178_I	0.664	0.34
421_Q	425_I	0.664	0.34
535_Y	539_A	0.664	0.34
39_G	88_L	0.664	0.34
373_W	377_M	0.664	0.34
347_N	393_N	0.663	0.34
15_R	249_S	0.663	0.34
326_K	495_E	0.662	0.34
44_A	195_A	0.662	0.34
296_S	398_W	0.661	0.34
19_I	51_I	0.660	0.34
296_S	310_A	0.660	0.34
32_Y	54_L	0.659	0.34
317_I	347_N	0.657	0.33
502_A	506_A	0.656	0.33
253_N	315_K	0.656	0.33
103_I	321_V	0.656	0.33
177_Y	248_M	0.654	0.33
347_N	391_N	0.654	0.33
115_A	130_L	0.651	0.33
425_I	429_T	0.649	0.33
43_N	187_A	0.649	0.33
180_H	309_G	0.649	0.33
52_A	56_P	0.647	0.33
106_L	356_G	0.647	0.33
342_N	363_E	0.647	0.33
73_L	97_I	0.646	0.33
397_N	400_Q	0.645	0.33
98_V	146_L	0.644	0.32
306_G	310_A	0.643	0.32
346_L	366_G	0.643	0.32
35_G	293_H	0.642	0.32
212_Y	312_D	0.642	0.32
300_F	309_G	0.641	0.32
187_A	245_Y	0.640	0.32
124_V	151_A	0.639	0.32
287_S	401_A	0.639	0.32
456_N	486_N	0.639	0.32
140_L	152_I	0.639	0.32
542_F	551_I	0.638	0.32
354_V	357_F	0.638	0.32
160_I	452_K	0.638	0.32
354_V	360_N	0.638	0.32
439_T	481_A	0.636	0.32
340_L	372_V	0.636	0.32
14_A	465_G	0.636	0.32
128_K	155_A	0.636	0.32
84_L	87_D	0.636	0.32
467_T	528_L	0.634	0.32
170_V	308_I	0.634	0.32
219_M	395_D	0.633	0.32
84_L	103_I	0.631	0.32
459_D	492_F	0.631	0.32
310_A	313_S	0.631	0.32
533_N	539_A	0.630	0.31
321_V	411_V	0.630	0.31
62_G	409_R	0.630	0.31
67_V	297_T	0.630	0.31
449_N	490_N	0.627	0.31
361_T	368_N	0.627	0.31
10_L	23_A	0.627	0.31
62_G	422_E	0.626	0.31
17_A	20_A	0.624	0.31
424_L	440_L	0.624	0.31
21_R	352_R	0.624	0.31
171_A	219_M	0.622	0.31
141_A	144_L	0.621	0.31
128_K	157_D	0.621	0.31
397_N	401_A	0.621	0.31
18_A	230_A	0.621	0.31
60_R	505_L	0.621	0.31
26_H	57_F	0.621	0.31
129_F	133_V	0.620	0.31
291_T	402_L	0.619	0.31
18_A	53_E	0.619	0.31
535_Y	554_A	0.619	0.31
225_T	321_V	0.618	0.31
322_G	334_V	0.618	0.31
268_E	498_D	0.618	0.31
495_E	499_M	0.617	0.31
165_H	254_I	0.617	0.31
359_A	369_Q	0.616	0.30
428_L	464_L	0.616	0.30
537_Q	541_E	0.615	0.30
34_G	72_I	0.614	0.30
316_F	347_N	0.614	0.30
390_L	421_Q	0.613	0.30
203_K	396_H	0.612	0.30
20_A	65_I	0.612	0.30
325_V	386_P	0.611	0.30
446_E	512_S	0.609	0.30
330_D	463_K	0.609	0.30
152_I	497_A	0.607	0.30
419_G	484_V	0.607	0.30
26_H	308_I	0.607	0.30
239_F	295_G	0.606	0.30
346_L	362_V	0.606	0.30
31_V	134_G	0.606	0.30
18_A	38_F	0.606	0.30
357_F	360_N	0.606	0.30
61_Y	468_L	0.606	0.30
151_A	484_V	0.605	0.30
61_Y	299_Y	0.605	0.30
444_F	479_P	0.605	0.30
180_H	193_S	0.604	0.30
521_P	525_Q	0.603	0.30
35_G	310_A	0.600	0.29
8_L	394_L	0.600	0.29
267_E	519_P	0.600	0.29
464_L	500_L	0.600	0.29
85_I	195_A	0.599	0.29
463_K	471_A	0.598	0.29
31_V	63_A	0.598	0.29
417_L	484_V	0.596	0.29
58_A	297_T	0.594	0.29
60_R	468_L	0.593	0.29
29_D	66_F	0.592	0.29
295_G	399_Q	0.591	0.29
115_A	135_F	0.591	0.29
78_L	526_T	0.591	0.29
162_F	234_A	0.590	0.29
54_L	68_T	0.590	0.29
247_D	332_L	0.590	0.29
540_R	543_Y	0.589	0.29
126_K	135_F	0.589	0.29
106_L	109_P	0.589	0.29
416_E	429_T	0.588	0.29
101_M	371_R	0.587	0.28
56_P	545_R	0.583	0.28
220_K	245_Y	0.583	0.28
91_T	171_A	0.583	0.28
140_L	160_I	0.582	0.28
293_H	300_F	0.581	0.28
24_I	157_D	0.581	0.28
269_R	381_L	0.580	0.28
28_A	319_L	0.579	0.28
101_M	119_C	0.578	0.28
79_E	435_S	0.577	0.28
43_N	177_Y	0.577	0.28
420_W	517_A	0.577	0.28
6_H	367_E	0.577	0.28
307_D	551_I	0.576	0.28
19_I	22_E	0.576	0.28
162_F	239_F	0.575	0.28
149_I	234_A	0.574	0.28
25_L	170_V	0.574	0.28
42_H	171_A	0.573	0.28
452_K	456_N	0.573	0.28
446_E	480_G	0.573	0.28
131_S	155_A	0.573	0.28
218_S	318_G	0.572	0.27
385_R	388_H	0.570	0.27
11_L	30_A	0.570	0.27
113_L	552_D	0.570	0.27
198_L	315_K	0.570	0.27
533_N	543_Y	0.569	0.27
62_G	509_Q	0.569	0.27
423_Q	482_L	0.569	0.27
434_V	507_S	0.569	0.27
68_T	93_V	0.569	0.27
76_D	156_T	0.568	0.27
220_K	308_I	0.568	0.27
288_T	410_R	0.568	0.27
51_I	248_M	0.566	0.27
127_A	141_A	0.565	0.27
33_I	297_T	0.565	0.27
339_P	414_D	0.564	0.27
290_K	317_I	0.564	0.27
170_V	204_D	0.564	0.27
175_Q	531_L	0.564	0.27
292_F	316_F	0.563	0.27
424_L	457_L	0.563	0.27
367_E	370_Y	0.562	0.27
35_G	54_L	0.561	0.27
340_L	545_R	0.561	0.27
310_A	314_P	0.560	0.27
310_A	347_N	0.560	0.27
165_H	175_Q	0.560	0.27
39_G	394_L	0.560	0.27
79_E	103_I	0.559	0.27
469_Y	486_N	0.559	0.27
402_L	484_V	0.558	0.27
396_H	489_L	0.558	0.27
126_K	130_L	0.558	0.27
56_P	475_Q	0.557	0.27
458_K	501_D	0.556	0.26
35_G	87_D	0.556	0.26
146_L	263_D	0.555	0.26
386_P	439_T	0.555	0.26
6_H	237_R	0.554	0.26
7_R	266_I	0.554	0.26
217_L	461_L	0.553	0.26
35_G	67_V	0.553	0.26
456_N	460_G	0.552	0.26
120_D	315_K	0.552	0.26
317_I	349_L	0.552	0.26
138_I	239_F	0.551	0.26
260_Q	264_A	0.551	0.26
532_A	543_Y	0.551	0.26
322_G	390_L	0.551	0.26
63_A	216_L	0.551	0.26
222_N	299_Y	0.550	0.26
216_L	348_V	0.550	0.26
149_I	390_L	0.550	0.26
359_A	372_V	0.549	0.26
19_I	247_D	0.548	0.26
21_R	293_H	0.548	0.26
464_L	469_Y	0.547	0.26
60_R	198_L	0.545	0.26
229_G	423_Q	0.544	0.26
283_F	541_E	0.543	0.26
25_L	184_G	0.543	0.26
55_V	111_I	0.542	0.26
439_T	446_E	0.542	0.26
264_A	281_E	0.542	0.26
97_I	225_T	0.542	0.26
288_T	296_S	0.540	0.25
64_K	256_A	0.539	0.25
216_L	452_K	0.539	0.25
417_L	492_F	0.538	0.25
26_H	406_S	0.537	0.25
342_N	346_L	0.537	0.25
8_L	72_I	0.537	0.25
50_D	54_L	0.536	0.25
239_F	402_L	0.536	0.25
103_I	108_I	0.535	0.25
11_L	238_S	0.535	0.25
332_L	384_I	0.535	0.25
32_Y	44_A	0.534	0.25
288_T	489_L	0.533	0.25
105_E	220_K	0.533	0.25
239_F	288_T	0.533	0.25
71_T	536_N	0.532	0.25
97_I	419_G	0.532	0.25
65_I	348_V	0.532	0.25
22_E	137_Q	0.531	0.25
428_L	472_R	0.531	0.25
220_K	302_N	0.531	0.25
216_L	464_L	0.531	0.25
73_L	222_N	0.531	0.25
428_L	498_D	0.531	0.25
428_L	500_L	0.530	0.25
220_K	296_S	0.530	0.25
538_K	542_F	0.529	0.25
139_V	255_T	0.528	0.25
290_K	345_G	0.528	0.25
78_L	170_V	0.527	0.25
537_Q	540_R	0.527	0.25
191_D	195_A	0.526	0.25
42_H	159_T	0.525	0.25
319_L	338_E	0.524	0.24
81_A	84_L	0.524	0.24
292_F	395_D	0.523	0.24
152_I	388_H	0.522	0.24
530_F	554_A	0.522	0.24
24_I	252_K	0.521	0.24
60_R	481_A	0.521	0.24
392_R	405_T	0.520	0.24
53_E	56_P	0.520	0.24
341_A	395_D	0.520	0.24
342_N	372_V	0.520	0.24
534_V	554_A	0.519	0.24
239_F	438_H	0.519	0.24
210_V	235_G	0.519	0.24
349_L	354_V	0.519	0.24
366_G	372_V	0.519	0.24
76_D	83_R	0.519	0.24
540_R	553_A	0.518	0.24
357_F	361_T	0.518	0.24
369_Q	373_W	0.517	0.24
534_V	551_I	0.517	0.24
155_A	160_I	0.517	0.24
524_P	528_L	0.517	0.24
245_Y	299_Y	0.516	0.24
249_S	403_T	0.516	0.24
136_T	507_S	0.516	0.24
42_H	96_L	0.516	0.24
534_V	543_Y	0.516	0.24
85_I	518_D	0.516	0.24
67_V	261_M	0.516	0.24
414_D	475_Q	0.515	0.24
290_K	316_F	0.515	0.24
124_V	303_A	0.515	0.24
59_H	65_I	0.514	0.24
177_Y	451_E	0.514	0.24
215_H	268_E	0.514	0.24
356_G	363_E	0.513	0.24
448_N	476_I	0.512	0.24
66_F	296_S	0.511	0.24
36_P	42_H	0.511	0.24
443_Q	521_P	0.511	0.24
35_G	127_A	0.511	0.24
48_L	52_A	0.510	0.24
143_E	168_L	0.510	0.24
146_L	310_A	0.509	0.24
61_Y	284_F	0.509	0.24
81_A	92_G	0.509	0.24
75_D	473_D	0.509	0.24
8_L	269_R	0.509	0.24
215_H	350_I	0.508	0.23
170_V	534_V	0.508	0.23
36_P	47_S	0.507	0.23
39_G	84_L	0.507	0.23
90_Q	328_A	0.507	0.23
220_K	293_H	0.507	0.23
122_R	141_A	0.507	0.23
159_T	316_F	0.505	0.23
73_L	257_H	0.505	0.23
367_E	376_E	0.505	0.23
52_A	509_Q	0.504	0.23
81_A	340_L	0.504	0.23
10_L	13_P	0.504	0.23
293_H	490_N	0.504	0.23
515_P	518_D	0.503	0.23
293_H	305_K	0.503	0.23
420_W	477_N	0.503	0.23
33_I	54_L	0.503	0.23
538_K	549_Q	0.502	0.23
293_H	353_E	0.501	0.23
528_L	536_N	0.501	0.23
112_E	184_G	0.500	0.23
154_Q	236_V	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2bdqA	2	0.2757	98.8	0.953	Contact Map
3o63A	2	0.2848	97.5	0.967	Contact Map
3f4wA	2	0.2175	97.4	0.968	Contact Map
4a29A	1	0.2067	97.3	0.968	Contact Map
1xi3A	2	0.3032	97.3	0.968	Contact Map
3q58A	2	0.2113	97.3	0.968	Contact Map
3igsA	1	0.2175	97.2	0.969	Contact Map
1h5yA	1	0.2282	97	0.97	Contact Map
3tsmA	2	0.2052	97	0.97	Contact Map
3qjaA	1	0.2282	97	0.97	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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