GREMLIN Database
YDCJ - Uncharacterized protein YdcJ
UniProt: P76097 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13753
Length: 447 (438)
Sequences: 391 (243)
Seq/√Len: 11.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
158_R179_E7.3151.00
300_P347_W6.7491.00
73_V82_L5.9381.00
85_M163_L5.7991.00
153_D160_R5.0421.00
85_M184_A4.7601.00
165_E176_Q4.3711.00
353_T356_G4.3621.00
369_P378_V4.2681.00
378_V444_C3.9450.99
341_R370_Q3.9110.99
378_V441_K3.7610.99
83_R424_C3.6360.99
336_S339_L3.5860.98
298_L333_F3.4640.98
113_P122_N3.4390.98
13_Q178_Q3.2190.97
173_N176_Q3.1530.96
28_Q31_T3.1120.96
163_L184_A3.1050.96
258_V337_E2.9640.95
339_L343_Q2.9350.95
84_R167_E2.7960.93
347_W430_F2.7290.92
75_T149_L2.6400.91
38_D242_C2.6360.91
234_R237_S2.5950.90
42_A238_M2.5880.90
418_F426_V2.4050.86
235_V244_I2.3990.86
138_N207_E2.3420.84
438_E442_R2.2660.82
23_Q166_Y2.2320.81
51_H55_V2.2180.81
148_I200_T2.2170.81
156_T186_E2.2070.81
346_A430_F2.1860.80
296_V346_A2.1760.80
81_T163_L2.1670.79
144_K203_A2.1530.79
28_Q200_T2.1140.78
319_N323_Q2.1010.77
159_C184_A2.0780.76
104_V398_Q2.0750.76
205_H209_R2.0060.74
352_L444_C1.9820.73
169_Q176_Q1.9650.72
158_R161_Q1.9330.71
113_P216_C1.9170.70
312_N332_T1.9120.70
373_I378_V1.8720.68
197_D200_T1.8650.68
234_R238_M1.8590.68
84_R164_E1.8490.67
81_T155_F1.8360.67
86_F128_T1.8310.66
352_L377_W1.8310.66
144_K197_D1.8120.66
300_P430_F1.7990.65
28_Q216_C1.7910.65
435_E439_R1.7760.64
28_Q197_D1.7190.61
240_P246_P1.7170.61
356_G377_W1.6820.59
28_Q65_V1.6580.58
12_E65_V1.6520.58
129_S391_V1.6290.57
40_N63_L1.6110.56
308_D312_N1.6020.56
349_R436_A1.5830.55
371_P375_R1.5700.54
31_T242_C1.5630.54
216_C380_A1.5550.53
296_V340_M1.5420.53
274_V285_T1.5310.52
341_R380_A1.5300.52
81_T160_R1.5210.52
116_D349_R1.5130.51
77_Q81_T1.5010.51
202_R206_N1.4660.49
28_Q274_V1.4530.48
250_I313_A1.4450.48
106_V129_S1.4390.48
56_N378_V1.4340.47
235_V246_P1.4210.47
311_R347_W1.4180.47
353_T377_W1.4020.46
106_V141_L1.4010.46
216_C384_T1.3970.46
210_L219_G1.3950.45
346_A413_A1.3790.45
303_R429_E1.3730.44
13_Q174_E1.3580.44
106_V391_V1.3420.43
313_A444_C1.3350.43
319_N322_H1.3330.42
92_Y134_E1.3270.42
351_R379_V1.3260.42
210_L220_C1.3170.42
46_N279_Q1.3030.41
114_I427_L1.2990.41
436_A439_R1.2970.41
10_I88_I1.2950.41
176_Q301_K1.2930.40
369_P441_K1.2900.40
44_L310_L1.2880.40
62_R75_T1.2860.40
156_T191_H1.2700.39
235_V238_M1.2670.39
61_A134_E1.2610.39
214_V248_I1.2550.39
145_A215_V1.2490.38
214_V402_G1.2470.38
244_I384_T1.2390.38
122_N216_C1.2280.37
161_Q332_T1.2280.37
338_F370_Q1.2270.37
346_A437_E1.2260.37
347_W444_C1.2250.37
344_G437_E1.2200.37
9_E41_L1.2190.37
163_L218_P1.2170.37
301_K343_Q1.2140.37
328_E331_R1.2060.36
205_H285_T1.2020.36
8_D118_S1.2020.36
308_D374_E1.2000.36
77_Q237_S1.2000.36
336_S370_Q1.1990.36
11_R14_F1.1800.35
62_R266_S1.1750.35
110_A285_T1.1720.35
283_T411_G1.1700.35
110_A268_K1.1650.35
198_E202_R1.1640.35
122_N197_D1.1630.34
175_T237_S1.1630.34
6_T305_L1.1620.34
82_L218_P1.1590.34
106_V220_C1.1580.34
116_D436_A1.1570.34
218_P274_V1.1540.34
230_L394_A1.1490.34
268_K285_T1.1470.34
325_H329_T1.1400.33
7_A166_Y1.1260.33
80_A83_R1.1210.33
256_R330_F1.1150.32
229_T235_V1.1140.32
178_Q366_G1.1130.32
12_E122_N1.1060.32
435_E438_E1.1020.32
260_I305_L1.0970.32
234_R366_G1.0940.31
23_Q137_E1.0910.31
7_A237_S1.0900.31
156_T187_T1.0890.31
40_N104_V1.0840.31
28_Q240_P1.0790.31
102_A180_F1.0780.31
28_Q59_E1.0770.31
39_V235_V1.0750.31
119_L266_S1.0700.30
28_Q347_W1.0680.30
6_T10_I1.0660.30
54_M248_I1.0550.30
101_Q113_P1.0520.30
233_D268_K1.0480.30
31_T197_D1.0480.30
58_D216_C1.0460.29
18_M398_Q1.0460.29
46_N114_I1.0440.29
73_V108_S1.0430.29
246_P414_S1.0410.29
210_L326_L1.0410.29
12_E16_Q1.0410.29
43_V368_D1.0390.29
218_P318_D1.0390.29
79_L138_N1.0380.29
318_D323_Q1.0330.29
352_L357_E1.0300.29
100_S122_N1.0280.29
86_F126_V1.0280.29
315_T318_D1.0210.28
195_T216_C1.0170.28
283_T369_P1.0170.28
371_P431_Q1.0120.28
113_P316_G1.0120.28
186_E189_R1.0110.28
247_K284_H1.0070.28
28_Q63_L0.9970.27
143_Q146_A0.9950.27
340_M346_A0.9890.27
45_E304_Q0.9880.27
255_R409_S0.9870.27
216_C346_A0.9860.27
347_W352_L0.9820.27
380_A444_C0.9780.27
338_F374_E0.9750.27
137_E207_E0.9720.27
129_S220_C0.9700.26
283_T434_Q0.9690.26
140_I373_I0.9680.26
193_S218_P0.9670.26
183_E285_T0.9660.26
59_E63_L0.9590.26
322_H326_L0.9530.26
75_T416_E0.9490.26
190_W330_F0.9490.26
248_I318_D0.9460.26
139_E181_V0.9450.25
61_A199_E0.9440.25
46_N439_R0.9430.25
43_V53_K0.9360.25
194_A274_V0.9320.25
5_I61_A0.9300.25
245_E381_Q0.9300.25
174_E178_Q0.9290.25
310_L422_L0.9270.25
33_L37_A0.9260.25
40_N102_A0.9220.25
133_L189_R0.9200.25
113_P207_E0.9170.24
47_N331_R0.9110.24
133_L391_V0.9100.24
89_M180_F0.9090.24
115_D165_E0.9060.24
238_M241_E0.9050.24
304_Q373_I0.9010.24
190_W286_A0.9000.24
113_P351_R0.9000.24
211_I215_V0.9000.24
220_C314_G0.9000.24
229_T310_L0.8970.24
216_C383_I0.8920.24
159_C414_S0.8910.24
17_A181_V0.8890.23
312_N329_T0.8880.23
100_S128_T0.8840.23
413_A417_A0.8840.23
317_Q347_W0.8800.23
190_W256_R0.8790.23
83_R426_V0.8780.23
91_M185_L0.8780.23
321_T324_M0.8750.23
258_V336_S0.8720.23
158_R324_M0.8660.23
101_Q122_N0.8650.23
331_R416_E0.8650.23
357_E368_D0.8650.23
114_I369_P0.8640.23
314_G322_H0.8620.22
139_E383_I0.8610.22
126_V300_P0.8610.22
313_A325_H0.8600.22
133_L211_I0.8550.22
200_T216_C0.8530.22
23_Q207_E0.8530.22
122_N316_G0.8490.22
330_F335_D0.8460.22
96_Y107_H0.8450.22
12_E23_Q0.8450.22
110_A293_Q0.8450.22
65_V113_P0.8420.22
20_A355_S0.8410.22
237_S241_E0.8400.22
62_R119_L0.8400.22
7_A20_A0.8400.22
57_A113_P0.8370.22
217_F284_H0.8350.22
7_A283_T0.8340.22
407_T432_L0.8330.22
164_E167_E0.8310.21
63_L291_I0.8310.21
85_M293_Q0.8300.21
211_I258_V0.8230.21
353_T406_Q0.8220.21
366_G377_W0.8220.21
157_P373_I0.8210.21
107_H132_R0.8200.21
168_Q278_G0.8160.21
158_R363_I0.8160.21
110_A270_L0.8120.21
28_Q122_N0.8110.21
100_S136_I0.8110.21
251_E286_A0.8100.21
207_E216_C0.8100.21
197_D216_C0.8090.21
159_C220_C0.8090.21
245_E349_R0.8070.21
114_I365_P0.8060.21
46_N411_G0.8040.21
174_E353_T0.8010.20
130_L291_I0.7990.20
362_A375_R0.7990.20
28_Q195_T0.7980.20
364_H442_R0.7970.20
351_R383_I0.7970.20
321_T373_I0.7970.20
339_L342_Q0.7960.20
430_F436_A0.7960.20
8_D17_A0.7910.20
53_K434_Q0.7910.20
251_E256_R0.7910.20
274_V424_C0.7880.20
316_G381_Q0.7860.20
92_Y378_V0.7860.20
4_S150_R0.7860.20
76_A362_A0.7860.20
190_W251_E0.7860.20
217_F286_A0.7860.20
10_I163_L0.7850.20
133_L214_V0.7820.20
365_P377_W0.7790.20
146_A150_R0.7790.20
229_T285_T0.7770.20
278_G375_R0.7750.20
34_E312_N0.7750.20
175_T308_D0.7750.20
321_T325_H0.7740.20
117_A199_E0.7730.20
82_L210_L0.7720.20
60_L240_P0.7710.20
341_R350_Y0.7710.20
189_R391_V0.7710.20
342_Q380_A0.7680.19
48_P60_L0.7650.19
10_I89_M0.7620.19
172_F268_K0.7600.19
65_V216_C0.7590.19
196_V215_V0.7590.19
4_S121_R0.7580.19
391_V419_E0.7560.19
220_C391_V0.7560.19
137_E214_V0.7520.19
130_L205_H0.7500.19
337_E348_F0.7500.19
284_H330_F0.7490.19
50_L148_I0.7480.19
333_F430_F0.7470.19
57_A122_N0.7460.19
20_A406_Q0.7430.19
351_R380_A0.7420.19
43_V50_L0.7420.19
57_A65_V0.7420.19
255_R317_Q0.7420.19
40_N60_L0.7420.19
40_N138_N0.7400.19
197_D203_A0.7390.19
383_I430_F0.7370.18
47_N281_Q0.7360.18
369_P444_C0.7340.18
197_D346_A0.7330.18
171_G177_A0.7320.18
339_L438_E0.7310.18
271_E383_I0.7300.18
203_A373_I0.7290.18
208_H256_R0.7280.18
148_I196_V0.7270.18
190_W217_F0.7240.18
161_Q416_E0.7240.18
77_Q151_Q0.7230.18
210_L215_V0.7230.18
244_I266_S0.7230.18
378_V436_A0.7220.18
207_E384_T0.7200.18
117_A138_N0.7190.18
175_T178_Q0.7170.18
77_Q80_A0.7150.18
353_T412_N0.7140.18
100_S424_C0.7140.18
139_E328_E0.7140.18
331_R415_R0.7130.18
217_F251_E0.7120.18
247_K251_E0.7120.18
107_H217_F0.7100.18
129_S348_F0.7080.18
303_R307_D0.7080.18
256_R286_A0.7080.18
34_E146_A0.7070.18
320_L324_M0.7060.18
56_N384_T0.7060.18
107_H251_E0.7060.18
195_T200_T0.7050.18
184_A274_V0.7050.18
190_W208_H0.7040.18
96_Y132_R0.7030.17
10_I159_C0.7020.17
321_T404_E0.7020.17
77_Q150_R0.6990.17
52_E347_W0.6970.17
143_Q324_M0.6970.17
110_A298_L0.6950.17
323_Q329_T0.6950.17
171_G181_V0.6920.17
122_N430_F0.6910.17
101_Q216_C0.6900.17
84_R301_K0.6890.17
203_A214_V0.6880.17
57_A384_T0.6880.17
196_V244_I0.6870.17
96_Y284_H0.6870.17
138_N181_V0.6850.17
250_I417_A0.6820.17
219_G391_V0.6810.17
132_R418_F0.6800.17
304_Q308_D0.6770.17
7_A160_R0.6770.17
129_S138_N0.6750.17
107_H247_K0.6730.17
185_L211_I0.6730.17
96_Y209_R0.6720.17
434_Q438_E0.6710.17
377_W383_I0.6700.17
134_E421_A0.6700.17
23_Q28_Q0.6690.17
24_Q55_V0.6690.17
347_W414_S0.6680.17
15_S82_L0.6670.16
141_L196_V0.6660.16
369_P383_I0.6660.16
271_E285_T0.6650.16
100_S113_P0.6610.16
62_R227_P0.6610.16
236_Q286_A0.6590.16
251_E330_F0.6590.16
76_A206_N0.6580.16
395_G399_S0.6560.16
396_I399_S0.6560.16
20_A192_Q0.6550.16
184_A266_S0.6540.16
248_I316_G0.6530.16
134_E137_E0.6510.16
416_E420_Q0.6510.16
80_A278_G0.6500.16
76_A285_T0.6490.16
291_I391_V0.6480.16
223_N226_T0.6460.16
219_G291_I0.6450.16
214_V242_C0.6450.16
274_V305_L0.6440.16
326_L330_F0.6440.16
251_E284_H0.6430.16
147_E331_R0.6430.16
53_K63_L0.6420.16
51_H56_N0.6420.16
146_A151_Q0.6400.16
169_Q347_W0.6380.16
31_T240_P0.6370.16
236_Q256_R0.6360.16
129_S181_V0.6360.16
164_E317_Q0.6350.16
242_C439_R0.6350.16
58_D383_I0.6340.16
82_L245_E0.6340.16
202_R374_E0.6340.16
158_R434_Q0.6330.16
244_I270_L0.6320.16
166_Y427_L0.6300.15
368_D438_E0.6300.15
375_R378_V0.6300.15
217_F330_F0.6270.15
8_D87_A0.6270.15
40_N180_F0.6270.15
191_H293_Q0.6270.15
5_I434_Q0.6260.15
208_H246_P0.6250.15
249_L398_Q0.6250.15
88_I215_V0.6250.15
31_T214_V0.6240.15
82_L197_D0.6240.15
257_E327_Q0.6230.15
416_E443_R0.6220.15
208_H330_F0.6210.15
33_L58_D0.6190.15
103_G208_H0.6190.15
89_M167_E0.6190.15
42_A237_S0.6180.15
88_I172_F0.6170.15
23_Q315_T0.6160.15
286_A330_F0.6140.15
39_V238_M0.6140.15
113_P318_D0.6130.15
226_T290_E0.6120.15
158_R241_E0.6110.15
73_V414_S0.6110.15
41_L362_A0.6100.15
190_W284_H0.6100.15
380_A403_N0.6100.15
186_E210_L0.6090.15
260_I293_Q0.6090.15
325_H328_E0.6080.15
296_V430_F0.6070.15
209_R398_Q0.6060.15
107_H284_H0.6060.15
104_V155_F0.6060.15
165_E250_I0.6060.15
298_L346_A0.6040.15
104_V209_R0.6020.15
256_R335_D0.6010.15
300_P305_L0.6010.15
59_E195_T0.6000.15
132_R330_F0.6000.15
102_A298_L0.5990.15
47_N411_G0.5990.15
178_Q443_R0.5980.15
80_A210_L0.5980.15
9_E92_Y0.5950.15
44_L49_Q0.5950.15
236_Q330_F0.5940.15
150_R431_Q0.5930.15
46_N121_R0.5930.15
363_I442_R0.5930.15
166_Y373_I0.5930.15
64_N81_T0.5920.15
130_L391_V0.5910.15
247_K286_A0.5900.14
215_V391_V0.5890.14
139_E301_K0.5880.14
190_W236_Q0.5870.14
120_A436_A0.5870.14
190_W247_K0.5870.14
137_E250_I0.5860.14
102_A154_I0.5860.14
64_N347_W0.5840.14
166_Y337_E0.5830.14
58_D121_R0.5820.14
35_L314_G0.5820.14
141_L215_V0.5810.14
217_F247_K0.5800.14
103_G310_L0.5800.14
153_D319_N0.5800.14
107_H286_A0.5790.14
5_I9_E0.5780.14
132_R335_D0.5760.14
54_M104_V0.5750.14
77_Q241_E0.5750.14
423_G440_S0.5740.14
129_S417_A0.5730.14
107_H190_W0.5730.14
136_I197_D0.5730.14
95_S442_R0.5720.14
88_I348_F0.5720.14
132_R284_H0.5720.14
160_R323_Q0.5720.14
205_H373_I0.5710.14
42_A173_N0.5690.14
214_V398_Q0.5690.14
300_P434_Q0.5690.14
82_L408_R0.5670.14
215_V235_V0.5660.14
102_A398_Q0.5660.14
235_V415_R0.5650.14
107_H330_F0.5650.14
434_Q437_E0.5630.14
38_D146_A0.5620.14
397_F400_N0.5610.14
396_I400_N0.5610.14
395_G400_N0.5610.14
236_Q251_E0.5610.14
121_R365_P0.5610.14
190_W335_D0.5600.14
60_L183_E0.5600.14
102_A333_F0.5600.14
89_M134_E0.5590.14
271_E434_Q0.5590.14
271_E425_P0.5570.14
215_V348_F0.5570.14
270_L285_T0.5560.14
311_R378_V0.5560.14
187_T211_I0.5550.14
316_G325_H0.5540.14
89_M429_E0.5540.14
35_L163_L0.5530.14
268_K322_H0.5530.14
76_A178_Q0.5520.14
275_L383_I0.5510.14
120_A336_S0.5510.14
5_I195_T0.5510.14
250_I324_M0.5490.14
223_N290_E0.5490.14
108_S137_E0.5480.13
101_Q316_G0.5470.13
44_L54_M0.5460.13
315_T325_H0.5440.13
17_A21_M0.5440.13
135_L229_T0.5440.13
106_V187_T0.5430.13
143_Q363_I0.5430.13
308_D332_T0.5420.13
96_Y217_F0.5420.13
208_H251_E0.5410.13
104_V245_E0.5410.13
261_L303_R0.5390.13
16_Q64_N0.5370.13
210_L298_L0.5370.13
413_A418_F0.5370.13
24_Q411_G0.5360.13
241_E344_G0.5350.13
81_T194_A0.5350.13
151_Q428_D0.5350.13
202_R373_I0.5340.13
301_K318_D0.5340.13
42_A381_Q0.5330.13
96_Y330_F0.5330.13
24_Q241_E0.5320.13
168_Q173_N0.5320.13
237_S257_E0.5320.13
45_E214_V0.5300.13
115_D374_E0.5300.13
428_D431_Q0.5280.13
314_G391_V0.5280.13
146_A371_P0.5280.13
18_M229_T0.5270.13
156_T211_I0.5270.13
118_S323_Q0.5250.13
81_T214_V0.5240.13
33_L323_Q0.5230.13
9_E436_A0.5230.13
87_A115_D0.5230.13
107_H208_H0.5230.13
87_A268_K0.5230.13
408_R411_G0.5220.13
215_V330_F0.5200.13
32_L62_R0.5190.13
275_L308_D0.5190.13
10_I429_E0.5180.13
349_R375_R0.5170.13
34_E336_S0.5170.13
275_L363_I0.5160.13
130_L219_G0.5160.13
5_I49_Q0.5150.13
235_V429_E0.5150.13
196_V211_I0.5130.13
316_G321_T0.5120.13
247_K330_F0.5120.13
184_A273_T0.5120.13
12_E179_E0.5120.13
216_C351_R0.5110.13
80_A134_E0.5100.13
207_E277_A0.5100.13
246_P319_N0.5100.13
194_A216_C0.5090.13
177_A196_V0.5090.13
36_V189_R0.5080.13
115_D369_P0.5070.13
76_A133_L0.5070.13
76_A343_Q0.5060.13
158_R175_T0.5060.13
4_S377_W0.5060.13
337_E380_A0.5060.13
368_D371_P0.5050.13
38_D375_R0.5040.13
336_S441_K0.5030.12
12_E56_N0.5000.12
27_P67_R0.5000.12
209_R240_P0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2rjbA 1 0.953 100 0.216 Contact Map
3iuzA 1 0.6063 100 0.613 Contact Map
3lhoA 1 0.5414 100 0.69 Contact Map
2pg4A 3 0.17 38.8 0.984 Contact Map
4pzjA 2 0.1387 31.7 0.985 Contact Map
2obpA 1 0.1365 30.1 0.985 Contact Map
2frhA 2 0.2573 28.3 0.985 Contact Map
1tbxA 3 0.2036 25.5 0.985 Contact Map
1xmaA 2 0.1834 22.9 0.986 Contact Map
2qvoA 2 0.1544 16.8 0.987 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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