GREMLIN Database
YNBD - Uncharacterized protein YnbD
UniProt: P76093 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13751
Length: 430 (400)
Sequences: 206 (134)
Seq/√Len: 6.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
16_F61_D5.6331.00
91_A136_I4.4730.98
49_F121_E4.0360.96
136_I185_V3.8170.94
253_G261_T3.3850.89
141_L161_F3.2780.87
288_S292_F3.0020.82
49_F69_F2.8400.78
26_T37_P2.8270.78
49_F91_A2.6940.74
91_A185_V2.6840.74
49_F172_W2.6340.72
67_S80_L2.6210.72
77_Q141_L2.5860.71
17_F24_Q2.5860.71
218_G247_L2.5710.71
362_L386_V2.5280.69
143_R190_D2.4280.66
270_L282_R2.4250.66
65_G389_A2.3420.63
296_L380_L2.2780.61
60_L138_C2.2680.60
24_Q28_V2.2360.59
51_P172_W2.2350.59
143_R187_M2.1930.58
191_W273_A2.1870.57
49_F109_V2.1700.57
219_A399_T2.1700.57
102_F381_S2.1330.55
88_T292_F2.1040.54
301_K305_G2.0940.54
344_M348_V2.0610.53
187_M190_D2.0240.51
88_T288_S2.0140.51
9_L147_Q2.0100.51
25_F29_Q2.0010.50
121_E172_W1.9640.49
26_T96_L1.9220.47
355_L385_L1.8900.46
301_K304_A1.8880.46
166_I218_G1.8790.46
252_R308_L1.8410.44
119_Q125_L1.8370.44
122_L125_L1.8190.44
64_Y168_T1.8120.43
26_T35_D1.7780.42
141_L145_F1.7560.41
136_I183_L1.7510.41
216_V287_L1.7490.41
136_I189_I1.7280.40
61_D106_R1.7170.40
40_V103_S1.7140.40
343_P346_D1.7120.40
248_L283_I1.7010.39
106_R172_W1.6920.39
179_V183_L1.6690.38
12_A68_L1.6510.38
286_W290_R1.6290.37
127_Y348_V1.6120.36
138_C158_G1.6110.36
22_L26_T1.6090.36
49_F70_V1.5870.35
165_A279_L1.5700.35
169_L181_T1.5620.34
102_F339_Y1.5610.34
51_P121_E1.5440.34
140_L184_A1.5430.34
52_W130_S1.5420.34
91_A272_P1.5240.33
288_S328_F1.5200.33
29_Q35_D1.5160.33
12_A282_R1.5100.33
212_A215_Y1.5020.32
13_P243_P1.4960.32
287_L291_W1.4950.32
53_T205_D1.4940.32
16_F106_R1.4940.32
302_M410_R1.4900.32
363_E366_R1.4890.32
50_L204_P1.4870.32
43_W378_L1.4840.32
388_A407_I1.4650.31
137_L378_L1.4550.31
189_I381_S1.4310.30
89_V276_W1.4250.30
88_T375_H1.4230.30
322_L362_L1.4190.30
77_Q161_F1.4120.30
373_L377_A1.4100.29
88_T180_I1.3980.29
52_W169_L1.3940.29
51_P61_D1.3920.29
68_L143_R1.3760.28
73_T79_R1.3750.28
23_N258_G1.3720.28
39_Q63_L1.3650.28
209_I269_K1.3580.28
142_W146_R1.3470.28
223_I340_F1.3440.27
189_I310_A1.3440.27
355_L372_V1.3240.27
103_S136_I1.3190.27
112_V166_I1.3160.27
39_Q324_V1.3130.27
13_P67_S1.3120.27
102_F365_L1.3070.26
70_V144_H1.2940.26
155_K222_C1.2870.26
12_A127_Y1.2850.26
26_T94_G1.2820.26
21_S24_Q1.2810.26
63_L324_V1.2780.26
58_W171_T1.2780.26
215_Y219_A1.2780.26
89_V166_I1.2760.25
307_Y394_Y1.2760.25
116_L388_A1.2720.25
12_A146_R1.2640.25
223_I236_W1.2620.25
4_G145_F1.2610.25
257_L275_Y1.2610.25
90_M196_D1.2530.25
12_A18_T1.2520.25
55_V112_V1.2480.25
324_V344_M1.2390.24
74_T286_W1.2390.24
22_L92_C1.2360.24
193_V261_T1.2300.24
7_W11_L1.2270.24
322_L365_L1.2260.24
38_S381_S1.2240.24
94_G199_W1.2200.24
149_L153_W1.2080.24
292_F326_F1.2070.24
172_W305_G1.2060.24
293_C373_L1.2060.24
7_W312_P1.2040.23
180_I288_S1.2010.23
378_L390_W1.1910.23
121_E321_V1.1900.23
5_A297_E1.1890.23
12_A91_A1.1870.23
303_T387_V1.1860.23
43_W137_L1.1750.23
4_G77_Q1.1750.23
66_F69_F1.1740.23
35_D68_L1.1650.22
34_H37_P1.1640.22
292_F328_F1.1630.22
141_L354_E1.1600.22
126_P182_G1.1600.22
61_D389_A1.1580.22
289_M310_A1.1540.22
15_F19_Y1.1500.22
16_F389_A1.1490.22
39_Q179_V1.1440.22
196_D355_L1.1430.22
127_Y206_Q1.1380.22
36_I41_F1.1360.22
37_P103_S1.1340.22
288_S375_H1.1330.22
292_F375_H1.1330.22
180_I292_F1.1290.22
374_V387_V1.1270.21
60_L262_T1.1250.21
122_L380_L1.1250.21
287_L318_Q1.1130.21
88_T200_N1.1110.21
276_W306_V1.1100.21
272_P338_L1.1080.21
24_Q27_A1.1070.21
58_W64_Y1.1020.21
41_F166_I1.1010.21
66_F238_V1.1000.21
213_L295_R1.0960.21
65_G156_V1.0960.21
75_F234_L1.0960.21
323_D327_E1.0950.21
252_R302_M1.0890.21
11_L312_P1.0870.20
161_F307_Y1.0870.20
181_T186_G1.0840.20
87_A381_S1.0840.20
127_Y165_A1.0830.20
53_T170_T1.0820.20
47_I108_E1.0820.20
89_V412_P1.0810.20
214_P405_S1.0800.20
22_L94_G1.0760.20
52_W326_F1.0740.20
160_W177_I1.0720.20
77_Q157_C1.0700.20
205_D208_R1.0680.20
68_L146_R1.0640.20
262_T285_M1.0620.20
89_V332_R1.0600.20
91_A98_Y1.0590.20
293_C310_A1.0590.20
59_S87_A1.0490.20
51_P101_K1.0480.20
96_L286_W1.0420.19
49_F321_V1.0360.19
63_L161_F1.0360.19
210_K214_P1.0340.19
76_E97_L1.0330.19
46_A220_G1.0300.19
124_D132_S1.0300.19
124_D131_P1.0300.19
124_D134_H1.0300.19
131_P134_H1.0300.19
49_F149_L1.0290.19
69_F109_V1.0290.19
34_H93_C1.0270.19
8_L64_Y1.0250.19
20_G43_W1.0160.19
255_G407_I1.0120.19
344_M386_V1.0100.19
94_G200_N1.0000.18
64_Y390_W0.9900.18
184_A407_I0.9900.18
107_P160_W0.9900.18
64_Y170_T0.9850.18
22_L310_A0.9820.18
191_W239_W0.9800.18
359_V386_V0.9800.18
50_L410_R0.9790.18
176_F239_W0.9770.18
248_L331_G0.9740.18
155_K185_V0.9700.18
123_F171_T0.9670.18
118_S138_C0.9670.18
184_A245_L0.9640.18
166_I227_E0.9630.18
108_E207_R0.9630.18
80_L274_V0.9580.17
77_Q397_C0.9560.17
351_E407_I0.9560.17
49_F66_F0.9540.17
23_N378_L0.9530.17
218_G278_T0.9520.17
191_W359_V0.9470.17
205_D209_I0.9470.17
89_V224_V0.9460.17
185_V400_V0.9440.17
25_F294_R0.9390.17
80_L144_H0.9390.17
302_M387_V0.9380.17
69_F343_P0.9350.17
85_I310_A0.9350.17
104_F312_P0.9280.17
100_L117_F0.9250.17
189_I296_L0.9240.17
9_L34_H0.9240.17
47_I300_S0.9220.17
130_S262_T0.9170.17
239_W324_V0.9170.17
295_R305_G0.9150.17
88_T92_C0.9080.16
9_L302_M0.9060.16
73_T246_S0.9040.16
293_C312_P0.9030.16
369_Q409_A0.9000.16
322_L386_V0.9000.16
16_F381_S0.8990.16
299_V385_L0.8990.16
217_V341_C0.8870.16
302_M407_I0.8870.16
70_V199_W0.8870.16
73_T198_R0.8840.16
253_G256_G0.8830.16
161_F350_P0.8810.16
23_N43_W0.8780.16
191_W200_N0.8770.16
11_L142_W0.8730.16
88_T139_W0.8700.16
145_F172_W0.8700.16
11_L68_L0.8690.16
17_F255_G0.8690.16
189_I193_V0.8680.16
52_W170_T0.8670.16
37_P63_L0.8660.16
168_T263_G0.8660.16
138_C344_M0.8640.16
285_M378_L0.8630.16
216_V414_I0.8560.15
130_S170_T0.8540.15
142_W158_G0.8520.15
127_Y224_V0.8510.15
64_Y186_G0.8500.15
51_P146_R0.8460.15
270_L306_V0.8450.15
21_S70_V0.8430.15
60_L141_L0.8410.15
206_Q340_F0.8390.15
89_V367_E0.8390.15
88_T168_T0.8380.15
339_Y365_L0.8370.15
18_T170_T0.8350.15
90_M219_A0.8330.15
104_F293_C0.8310.15
276_W366_R0.8310.15
17_F21_S0.8300.15
122_L189_I0.8290.15
160_W215_Y0.8280.15
53_T171_T0.8260.15
188_L402_E0.8240.15
97_L302_M0.8230.15
98_Y209_I0.8230.15
100_L327_E0.8230.15
40_V148_H0.8220.15
305_G317_A0.8220.15
74_T77_Q0.8200.15
170_T373_L0.8160.15
130_S169_L0.8150.15
17_F28_V0.8120.15
142_W381_S0.8110.15
214_P336_D0.8090.14
164_I378_L0.8090.14
185_V338_L0.8080.14
18_T168_T0.8050.14
65_G69_F0.8030.14
59_S160_W0.8020.14
285_M312_P0.8010.14
339_Y380_L0.8000.14
53_T378_L0.7990.14
44_E135_I0.7980.14
168_T390_W0.7970.14
8_L168_T0.7960.14
154_R349_V0.7960.14
155_K220_G0.7950.14
343_P405_S0.7930.14
52_W281_C0.7880.14
69_F321_V0.7880.14
5_A73_T0.7860.14
163_L391_L0.7860.14
26_T259_A0.7860.14
325_T328_F0.7860.14
39_Q385_L0.7850.14
11_L104_F0.7790.14
61_D381_S0.7770.14
64_Y123_F0.7760.14
185_V257_L0.7750.14
130_S285_M0.7740.14
42_G103_S0.7730.14
224_V367_E0.7710.14
318_Q338_L0.7690.14
48_P215_Y0.7680.14
112_V183_L0.7640.14
108_E270_L0.7640.14
80_L285_M0.7640.14
74_T80_L0.7630.14
16_F51_P0.7580.14
61_D141_L0.7570.14
193_V359_V0.7540.13
125_L362_L0.7530.13
154_R325_T0.7530.13
106_R381_S0.7490.13
110_S127_Y0.7490.13
79_R324_V0.7470.13
17_F259_A0.7460.13
192_M310_A0.7460.13
248_L353_G0.7440.13
350_P366_R0.7440.13
151_E307_Y0.7420.13
303_T402_E0.7420.13
194_P390_W0.7410.13
27_A284_G0.7400.13
53_T64_Y0.7390.13
7_W308_L0.7390.13
73_T356_R0.7370.13
193_V253_G0.7370.13
288_S380_L0.7370.13
96_L113_T0.7370.13
34_H42_G0.7360.13
293_C297_E0.7350.13
179_V407_I0.7340.13
236_W336_D0.7300.13
186_G390_W0.7290.13
165_A413_Q0.7270.13
67_S106_R0.7260.13
29_Q103_S0.7260.13
60_L285_M0.7200.13
37_P40_V0.7190.13
193_V238_V0.7180.13
40_V97_L0.7160.13
389_A411_R0.7140.13
372_V401_N0.7120.13
14_F184_A0.7120.13
110_S305_G0.7110.13
166_I204_P0.7090.13
205_D275_Y0.7080.13
52_W292_F0.7070.13
36_I127_Y0.7070.13
50_L166_I0.7050.13
12_A233_Q0.7030.13
127_Y358_A0.7020.13
45_T306_V0.6940.12
43_W164_I0.6940.12
135_I323_D0.6930.12
37_P236_W0.6920.12
200_N265_D0.6920.12
11_L308_L0.6900.12
87_A111_G0.6900.12
79_R363_E0.6870.12
68_L203_K0.6870.12
26_T115_W0.6850.12
345_L348_V0.6830.12
263_G271_P0.6820.12
251_G304_A0.6810.12
185_V209_I0.6810.12
211_I215_Y0.6800.12
75_F179_V0.6790.12
38_S142_W0.6770.12
51_P68_L0.6760.12
119_Q122_L0.6710.12
311_F373_L0.6710.12
51_P399_T0.6670.12
66_F407_I0.6660.12
51_P55_V0.6660.12
98_Y193_V0.6660.12
285_M389_A0.6650.12
201_Y294_R0.6640.12
235_W410_R0.6640.12
13_P68_L0.6620.12
13_P17_F0.6620.12
10_L353_G0.6620.12
292_F377_A0.6600.12
21_S28_V0.6590.12
59_S107_P0.6550.12
64_Y378_L0.6540.12
76_E188_L0.6530.12
397_C406_Y0.6530.12
4_G28_V0.6520.12
71_C144_H0.6510.12
210_K362_L0.6500.12
101_K220_G0.6460.12
38_S104_F0.6460.12
64_Y171_T0.6450.12
40_V65_G0.6450.12
98_Y270_L0.6450.12
168_T378_L0.6450.12
26_T63_L0.6440.12
188_L398_K0.6430.12
171_T182_G0.6400.12
8_L84_L0.6400.12
75_F311_F0.6380.12
238_V375_H0.6370.12
51_P210_K0.6360.12
60_L142_W0.6350.12
200_N362_L0.6330.12
18_T64_Y0.6330.12
278_T322_L0.6320.11
76_E148_H0.6300.11
166_I181_T0.6270.11
77_Q80_L0.6260.11
281_C285_M0.6260.11
67_S347_L0.6260.11
53_T390_W0.6250.11
130_S281_C0.6240.11
179_V283_I0.6240.11
199_W265_D0.6230.11
26_T385_L0.6230.11
311_F339_Y0.6230.11
165_A349_V0.6180.11
251_G305_G0.6170.11
28_V385_L0.6160.11
34_H398_K0.6140.11
180_I238_V0.6130.11
180_I373_L0.6120.11
185_V392_L0.6120.11
110_S400_V0.6120.11
22_L88_T0.6100.11
38_S209_I0.6100.11
79_R157_C0.6070.11
287_L314_H0.6070.11
242_W343_P0.6060.11
143_R307_Y0.6050.11
157_C296_L0.6050.11
269_K279_L0.6030.11
123_F137_L0.6010.11
213_L318_Q0.6010.11
21_S127_Y0.6000.11
242_W246_S0.6000.11
116_L378_L0.5950.11
61_D378_L0.5950.11
222_C401_N0.5950.11
93_C210_K0.5940.11
337_R405_S0.5940.11
246_S406_Y0.5910.11
347_L388_A0.5900.11
52_W262_T0.5870.11
61_D91_A0.5860.11
75_F283_I0.5850.11
64_Y114_G0.5840.11
87_A140_L0.5840.11
109_V296_L0.5830.11
82_H127_Y0.5830.11
392_L400_V0.5830.11
63_L139_W0.5820.11
39_Q241_C0.5810.11
104_F381_S0.5810.11
70_V253_G0.5810.11
86_L179_V0.5800.11
346_D358_A0.5800.11
16_F185_V0.5790.11
248_L409_A0.5780.11
58_W170_T0.5780.11
212_A269_K0.5770.11
21_S94_G0.5760.11
63_L300_S0.5750.11
60_L158_G0.5740.11
304_A396_H0.5720.11
23_N305_G0.5700.11
64_Y137_L0.5680.11
38_S413_Q0.5670.11
60_L106_R0.5660.11
202_Q398_K0.5660.11
81_V267_Q0.5620.10
53_T168_T0.5620.10
166_I341_C0.5620.10
23_N87_A0.5610.10
24_Q201_Y0.5580.10
9_L398_K0.5570.10
141_L319_N0.5570.10
304_A344_M0.5560.10
180_I273_A0.5560.10
221_S325_T0.5560.10
284_G341_C0.5550.10
68_L91_A0.5550.10
36_I171_T0.5550.10
196_D201_Y0.5550.10
64_Y130_S0.5520.10
210_K305_G0.5510.10
101_K146_R0.5500.10
287_L396_H0.5500.10
48_P254_Y0.5490.10
63_L136_I0.5490.10
35_D119_Q0.5470.10
179_V306_V0.5460.10
180_I375_H0.5460.10
22_L27_A0.5460.10
286_W289_M0.5450.10
42_G351_E0.5440.10
14_F393_C0.5420.10
55_V188_L0.5420.10
263_G274_V0.5420.10
69_F121_E0.5420.10
246_S338_L0.5410.10
233_Q398_K0.5390.10
155_K166_I0.5380.10
203_K209_I0.5360.10
51_P184_A0.5360.10
111_G186_G0.5350.10
72_S325_T0.5340.10
286_W381_S0.5340.10
38_S145_F0.5340.10
171_T243_P0.5330.10
87_A391_L0.5330.10
7_W13_P0.5310.10
396_H407_I0.5300.10
142_W211_I0.5290.10
276_W279_L0.5290.10
89_V153_W0.5280.10
213_L397_C0.5280.10
29_Q284_G0.5280.10
283_I369_Q0.5260.10
23_N64_Y0.5240.10
213_L266_S0.5240.10
206_Q353_G0.5240.10
170_T390_W0.5240.10
290_R329_P0.5230.10
88_T273_A0.5220.10
214_P324_V0.5210.10
64_Y84_L0.5200.10
16_F286_W0.5190.10
97_L223_I0.5170.10
10_L392_L0.5170.10
142_W160_W0.5170.10
139_W180_I0.5140.10
209_I362_L0.5120.10
172_W188_L0.5120.10
253_G271_P0.5110.10
240_L414_I0.5110.10
21_S199_W0.5100.10
216_V259_A0.5100.10
360_A406_Y0.5100.10
70_V324_V0.5090.10
153_W217_V0.5080.10
266_S336_D0.5070.10
137_L285_M0.5060.10
191_W288_S0.5050.10
16_F91_A0.5050.10
29_Q116_L0.5040.10
79_R177_I0.5020.10
88_T137_L0.5010.10
16_F115_W0.5010.10
118_S303_T0.5010.10
58_W262_T0.5010.10
305_G372_V0.5000.10
68_L243_P0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3emuA 1 0.3 99.9 0.875 Contact Map
4jmkA 1 0.3093 99.9 0.876 Contact Map
2nt2A 1 0.3047 99.9 0.876 Contact Map
3s4eA 1 0.3093 99.9 0.878 Contact Map
3ezzA 4 0.3093 99.9 0.879 Contact Map
2g6zA 3 0.314 99.9 0.879 Contact Map
2esbA 1 0.307 99.9 0.879 Contact Map
4y2eA 1 0.3093 99.9 0.88 Contact Map
2y96A 3 0.3488 99.9 0.88 Contact Map
2wgpA 5 0.3093 99.9 0.88 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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