GREMLIN Database
YNBB - Uncharacterized protein YnbB
UniProt: P76091 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13749
Length: 298 (256)
Sequences: 4752 (3605)
Seq/√Len: 225.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
41_T269_L6.2151.00
183_A215_T5.1351.00
194_R207_E4.1341.00
187_W211_G4.0861.00
209_L247_F3.6681.00
179_S219_A3.2801.00
253_M265_S3.0401.00
187_W215_T2.9541.00
189_K205_T2.8401.00
193_R207_E2.8131.00
71_A275_L2.8051.00
75_Y141_G2.7771.00
187_W191_C2.7461.00
174_L178_E2.6051.00
52_V63_F2.2371.00
42_W47_I2.2341.00
180_N247_F2.2181.00
39_I186_L2.1611.00
173_L286_A2.0991.00
35_V39_I2.0981.00
196_V209_L2.0551.00
78_L262_V2.0251.00
78_L265_S2.0241.00
172_F239_G2.0141.00
220_S239_G1.9801.00
70_L275_L1.9771.00
180_N243_G1.9671.00
194_R206_L1.9581.00
42_W46_V1.9411.00
272_H278_R1.9341.00
35_V186_L1.8981.00
55_G59_M1.8921.00
180_N246_G1.8771.00
186_L190_S1.8661.00
196_V206_L1.8031.00
73_K77_T1.7901.00
206_L210_M1.7841.00
210_M214_I1.7641.00
222_I226_L1.7241.00
184_Q212_G1.7211.00
235_A239_G1.6721.00
196_V251_V1.6641.00
177_T285_T1.6551.00
245_S288_V1.6511.00
187_W190_S1.6381.00
72_L76_C1.6291.00
279_I282_L1.6171.00
40_R44_G1.5781.00
148_A151_H1.5731.00
175_A219_A1.5611.00
234_Q292_F1.5551.00
67_I275_L1.5391.00
62_T66_L1.5211.00
238_A292_F1.4981.00
217_M236_L1.4871.00
195_K203_G1.4661.00
187_W214_I1.4591.00
136_S140_W1.4581.00
43_W47_I1.4561.00
218_I222_I1.4131.00
36_T40_R1.3941.00
66_L70_L1.3771.00
179_S215_T1.3771.00
173_L289_F1.3761.00
213_V243_G1.3521.00
213_V240_L1.3511.00
176_L220_S1.3301.00
151_H286_A1.3131.00
78_L260_I1.3071.00
73_K266_G1.2941.00
148_A152_A1.2871.00
245_S285_T1.2851.00
252_V284_F1.2801.00
216_I243_G1.2721.00
88_Y92_P1.2711.00
196_V210_M1.2561.00
50_S54_S1.2551.00
172_F223_I1.2531.00
71_A276_L1.2481.00
195_K205_T1.2481.00
222_I225_P1.2411.00
120_T123_V1.2371.00
177_T282_L1.2261.00
212_G243_G1.2111.00
72_L141_G1.1991.00
41_T270_P1.1961.00
217_M240_L1.1811.00
192_G207_E1.1781.00
99_G102_C1.1761.00
242_I289_F1.1751.00
231_N234_Q1.1611.00
209_L244_I1.1611.00
221_L236_L1.1561.00
176_L216_I1.1521.00
47_I51_M1.1401.00
151_H291_Y1.1381.00
183_A211_G1.1311.00
243_G247_F1.1301.00
41_T44_G1.1161.00
95_Y102_C1.1151.00
246_G281_S1.1111.00
152_A170_V1.1021.00
59_M62_T1.0991.00
45_I279_I1.0991.00
242_I285_T1.0961.00
216_I219_A1.0951.00
252_V256_I1.0891.00
75_Y79_I1.0831.00
177_T246_G1.0791.00
71_A279_I1.0771.00
39_I182_I1.0731.00
144_M148_A1.0631.00
67_I279_I1.0621.00
197_V200_V1.0611.00
35_V185_Y1.0611.00
56_P59_M1.0551.00
206_L209_L1.0541.00
51_M55_G1.0501.00
145_T283_I1.0491.00
45_I269_L1.0411.00
71_A145_T1.0241.00
189_K203_G1.0211.00
151_H290_F1.0171.00
58_W62_T1.0101.00
269_L275_L1.0081.00
90_G94_N1.0081.00
87_L93_L1.0011.00
174_L282_L0.9971.00
52_V56_P0.9961.00
41_T271_G0.9951.00
42_W186_L0.9941.00
145_T276_L0.9911.00
87_L94_N0.9841.00
233_L237_L0.9791.00
144_M253_M0.9681.00
172_F289_F0.9661.00
285_T289_F0.9601.00
37_L41_T0.9371.00
140_W144_M0.9331.00
39_I43_W0.9261.00
230_L234_Q0.9261.00
86_W91_I0.9181.00
60_T170_V0.9110.99
70_L73_K0.9090.99
108_L111_P0.9020.99
195_K198_P0.9000.99
64_F153_A0.8950.99
178_E272_H0.8950.99
86_W89_W0.8920.99
156_L167_A0.8890.99
91_I95_Y0.8860.99
154_W290_F0.8860.99
221_L225_P0.8800.99
194_R210_M0.8770.99
124_L127_D0.8760.99
144_M147_F0.8710.99
196_V247_F0.8690.99
132_L136_S0.8670.99
152_A286_A0.8600.99
113_A117_I0.8590.99
180_N212_G0.8540.99
89_W92_P0.8510.99
87_L95_Y0.8450.99
45_I48_C0.8420.99
215_T219_A0.8400.99
172_F220_S0.8400.99
88_Y103_F0.8360.99
266_G269_L0.8360.99
37_L40_R0.8340.99
180_N216_I0.8300.99
151_H154_W0.8270.99
253_M276_L0.8240.99
183_A212_G0.8240.99
234_Q238_A0.8200.99
121_G124_L0.8130.99
120_T124_L0.8120.99
183_A187_W0.8090.99
88_Y91_I0.8060.99
176_L239_G0.8040.99
147_F151_H0.8040.99
36_T39_I0.8030.99
86_W99_G0.7980.99
87_L91_I0.7970.99
152_A156_L0.7960.99
179_S183_A0.7930.99
61_L153_A0.7930.99
262_V265_S0.7930.99
92_P95_Y0.7920.99
42_W178_E0.7910.99
241_L292_F0.7880.98
59_M63_F0.7830.98
201_S204_K0.7810.98
117_I120_T0.7810.98
178_E278_R0.7810.98
191_C207_E0.7790.98
131_F140_W0.7770.98
244_I247_F0.7740.98
224_G235_A0.7730.98
44_G47_I0.7710.98
69_F73_K0.7640.98
203_G206_L0.7640.98
223_I227_L0.7590.98
123_V127_D0.7570.98
75_Y276_L0.7530.98
76_C138_I0.7520.98
200_V255_A0.7520.98
127_D246_G0.7490.98
144_M149_L0.7490.98
198_P209_L0.7480.98
88_Y93_L0.7460.98
188_G263_K0.7450.98
47_I50_S0.7400.98
40_R47_I0.7390.98
156_L166_G0.7340.98
53_I170_V0.7340.98
130_G133_H0.7340.98
47_I178_E0.7280.97
78_L256_I0.7220.97
98_I101_N0.7210.97
91_I96_L0.7190.97
96_L101_N0.7160.97
109_F112_L0.7140.97
113_A120_T0.7130.97
89_W96_L0.7130.97
177_T281_S0.7120.97
131_F134_T0.7050.97
252_V255_A0.7030.97
89_W94_N0.7030.97
95_Y99_G0.6980.97
183_A186_L0.6960.97
219_A223_I0.6950.97
97_L101_N0.6950.97
244_I248_C0.6910.97
236_L240_L0.6880.96
187_W205_T0.6860.96
48_C51_M0.6860.96
221_L232_T0.6840.96
197_V251_V0.6810.96
192_G205_T0.6810.96
176_L242_I0.6790.96
116_L119_A0.6780.96
217_M221_L0.6780.96
94_N101_N0.6750.96
250_D263_K0.6740.96
94_N98_I0.6710.96
151_H155_L0.6710.96
72_L75_Y0.6680.96
115_F122_Q0.6670.96
54_S167_A0.6670.96
216_I223_I0.6640.96
87_L98_I0.6640.96
95_Y100_F0.6630.96
239_G243_G0.6610.96
87_L92_P0.6600.95
188_G201_S0.6580.95
234_Q237_L0.6550.95
68_S149_L0.6540.95
196_V205_T0.6480.95
89_W99_G0.6470.95
144_M283_I0.6470.95
125_V129_S0.6460.95
63_F67_I0.6450.95
178_E182_I0.6450.95
204_K263_K0.6420.95
87_L100_F0.6390.95
201_S263_K0.6390.95
67_I149_L0.6370.95
48_C52_V0.6360.95
87_L90_G0.6340.94
78_L253_M0.6330.94
92_P96_L0.6320.94
193_R281_S0.6310.94
220_S235_A0.6310.94
45_I178_E0.6310.94
46_V50_S0.6300.94
86_W92_P0.6300.94
121_G125_V0.6290.94
152_A282_L0.6240.94
89_W95_Y0.6240.94
175_A179_S0.6210.94
275_L279_I0.6190.94
94_N97_L0.6190.94
141_G156_L0.6190.94
87_L97_L0.6160.94
105_L110_I0.6160.94
49_F178_E0.6150.93
89_W97_L0.6130.93
210_M213_V0.6120.93
105_L108_L0.6090.93
86_W102_C0.6090.93
96_L100_F0.6070.93
42_W272_H0.6070.93
39_I42_W0.6030.93
177_T265_S0.6020.93
205_T247_F0.5970.92
38_R265_S0.5910.92
39_I190_S0.5900.92
142_W146_V0.5900.92
173_L282_L0.5890.92
70_L266_G0.5860.92
114_G125_V0.5850.92
88_Y95_Y0.5850.92
99_G103_F0.5830.92
178_E282_L0.5820.91
253_M256_I0.5810.91
112_L116_L0.5800.91
141_G144_M0.5790.91
146_V149_L0.5770.91
92_P98_I0.5760.91
209_L213_V0.5740.91
170_V252_V0.5730.91
274_G277_D0.5730.91
92_P101_N0.5730.91
96_L99_G0.5710.91
95_Y101_N0.5700.91
124_L128_P0.5690.91
55_G58_W0.5680.90
268_L275_L0.5670.90
282_L286_A0.5650.90
171_L175_A0.5640.90
72_L145_T0.5610.90
88_Y100_F0.5600.90
41_T45_I0.5600.90
201_S273_G0.5570.90
155_L290_F0.5570.90
123_V128_P0.5540.89
194_R199_K0.5530.89
197_V203_G0.5520.89
89_W93_L0.5470.89
91_I94_N0.5450.89
61_L65_A0.5430.88
87_L101_N0.5420.88
88_Y94_N0.5410.88
91_I100_F0.5410.88
60_T153_A0.5380.88
54_S179_S0.5380.88
177_T253_M0.5370.88
107_L111_P0.5360.88
220_S224_G0.5330.88
173_L177_T0.5310.87
64_F288_V0.5310.87
206_L266_G0.5290.87
188_G202_P0.5290.87
216_I239_G0.5280.87
224_G232_T0.5280.87
246_G285_T0.5270.87
79_I260_I0.5270.87
209_L243_G0.5250.87
58_W103_F0.5240.87
195_K206_L0.5240.87
218_I233_L0.5240.87
182_I215_T0.5240.87
98_I103_F0.5240.87
273_G277_D0.5230.87
91_I99_G0.5220.86
204_K208_G0.5220.86
223_I226_L0.5220.86
73_K268_L0.5210.86
263_K273_G0.5210.86
112_L117_I0.5200.86
57_R156_L0.5190.86
266_G287_P0.5190.86
119_A122_Q0.5170.86
207_E272_H0.5160.86
95_Y103_F0.5160.86
77_T81_V0.5150.86
152_A174_L0.5140.86
241_L288_V0.5130.86
46_V186_L0.5120.85
116_L121_G0.5110.85
123_V126_G0.5100.85
204_K273_G0.5100.85
44_G48_C0.5100.85
183_A219_A0.5100.85
49_F53_I0.5080.85
90_G93_L0.5070.85
90_G97_L0.5060.85
188_G204_K0.5060.85
276_L279_I0.5050.85
49_F279_I0.5020.84
100_F103_F0.5020.84
42_W45_I0.5010.84
98_I102_C0.5010.84
178_E184_Q0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4q2eA 2 0.849 100 0.209 Contact Map
2wswA 3 0.2819 9.5 0.965 Contact Map
3oufA 4 0.1275 5.5 0.969 Contact Map
2k1kA 2 0.1275 2.7 0.973 Contact Map
2q67A 3 0.094 2.5 0.974 Contact Map
2kogA 1 0.1946 2.2 0.975 Contact Map
3hd6A 3 0.8725 2.1 0.975 Contact Map
2mpnA 2 0.198 2 0.975 Contact Map
4ev6A 3 0.2584 1.8 0.976 Contact Map
4huqS 1 0.5168 1.8 0.976 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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