GREMLIN Database
YCJN - Putative ABC transporter periplasmic-binding protein YcjN
UniProt: P76042 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13911
Length: 430 (392)
Sequences: 30321 (24524)
Seq/√Len: 1238.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
30_S63_K3.7291.00
411_D414_T3.1591.00
32_E63_K3.1421.00
154_K283_G3.1231.00
172_L236_D3.0751.00
228_M413_S3.0251.00
30_S61_T2.9631.00
155_D281_N2.8901.00
235_R239_A2.7301.00
109_A136_S2.7061.00
236_D240_N2.6281.00
167_N170_Q2.5391.00
154_K158_A2.4291.00
225_P229_Q2.4151.00
176_Q240_N2.4061.00
60_I314_A2.3221.00
54_E61_T2.3001.00
71_A74_T2.2791.00
232_T236_D2.2271.00
420_Q424_D2.2031.00
47_S51_A2.2011.00
232_T412_L2.1931.00
173_D177_K2.1921.00
32_E65_V2.1921.00
404_N409_K2.1811.00
111_A136_S2.1411.00
52_R321_F2.1341.00
52_R55_K2.1301.00
152_Y283_G2.1281.00
162_L174_V2.1251.00
413_S417_Q2.1221.00
324_Q327_N2.1211.00
410_A418_A2.1201.00
417_Q421_K2.1181.00
404_N410_A2.0911.00
48_K51_A2.0251.00
317_K320_T1.9531.00
309_T312_T1.8841.00
170_Q173_D1.8821.00
155_D159_K1.8761.00
229_Q232_T1.8751.00
157_L262_M1.8701.00
311_E314_A1.8691.00
43_Q47_S1.8661.00
52_R330_D1.8551.00
329_A333_M1.8481.00
28_N61_T1.8481.00
29_V314_A1.8471.00
53_F317_K1.8281.00
228_M232_T1.8111.00
397_V422_K1.8091.00
173_D176_Q1.7751.00
52_R56_E1.7751.00
51_A55_K1.7741.00
124_D128_R1.7701.00
87_E311_E1.7411.00
247_D250_E1.7381.00
418_A422_K1.7331.00
176_Q180_D1.7311.00
113_V316_E1.7271.00
172_L176_Q1.7131.00
50_I54_E1.6851.00
396_G400_S1.6771.00
313_E317_K1.6651.00
169_Q172_L1.6601.00
414_T418_A1.6361.00
121_A345_A1.6311.00
223_D417_Q1.6221.00
405_V415_T1.6181.00
330_D334_M1.6161.00
156_V261_P1.6161.00
105_I304_T1.6021.00
140_G302_T1.5931.00
130_V302_T1.5931.00
232_T413_S1.5911.00
54_E58_P1.5841.00
50_I318_F1.5731.00
48_K52_R1.5631.00
325_A329_A1.5571.00
401_M418_A1.5551.00
34_M79_L1.5461.00
132_T138_W1.5421.00
417_Q420_Q1.5391.00
254_A259_T1.5381.00
327_N330_D1.5321.00
401_M404_N1.5291.00
128_R132_T1.5281.00
233_Y236_D1.5241.00
172_L240_N1.5201.00
13_V16_A1.5181.00
14_S17_L1.5121.00
414_T417_Q1.5061.00
235_R405_V1.5041.00
75_K79_L1.4991.00
172_L237_L1.4901.00
89_I306_G1.4851.00
29_V311_E1.4841.00
401_M410_A1.4831.00
152_Y285_V1.4681.00
169_Q173_D1.4551.00
418_A421_K1.4551.00
362_G366_N1.4471.00
215_N219_K1.4451.00
189_A260_A1.4431.00
51_A54_E1.4401.00
68_E71_A1.4371.00
178_L261_P1.4331.00
35_H64_Q1.4291.00
226_E229_Q1.4191.00
150_I285_V1.4111.00
172_L233_Y1.4061.00
228_M412_L1.4031.00
314_A317_K1.3991.00
154_K281_N1.3971.00
253_D257_N1.3891.00
223_D420_Q1.3721.00
410_A415_T1.3621.00
363_E367_Q1.3531.00
330_D333_M1.3501.00
305_A319_V1.3481.00
156_V178_L1.3451.00
109_A112_T1.3361.00
162_L177_K1.3311.00
91_T304_T1.3161.00
53_F321_F1.3121.00
405_V412_L1.3121.00
363_E366_N1.3051.00
233_Y237_L1.2871.00
80_S85_L1.2871.00
158_A164_E1.2851.00
11_A15_C1.2751.00
50_I64_Q1.2751.00
174_V177_K1.2691.00
255_F282_V1.2661.00
225_P228_M1.2531.00
100_D139_T1.2441.00
316_E320_T1.2381.00
44_A47_S1.2371.00
53_F318_F1.2341.00
359_K363_E1.2321.00
88_V315_A1.2311.00
236_D239_A1.2311.00
28_N59_G1.2261.00
229_Q233_Y1.2211.00
410_A414_T1.2201.00
343_N346_V1.2041.00
232_T235_R1.2001.00
53_F60_I1.2001.00
401_M419_S1.1991.00
165_P170_Q1.1911.00
212_N215_N1.1891.00
397_V400_S1.1881.00
157_L174_V1.1771.00
166_K170_Q1.1741.00
175_A262_M1.1731.00
56_E324_Q1.1731.00
153_R156_V1.1721.00
325_A345_A1.1651.00
404_N418_A1.1631.00
160_A178_L1.1621.00
309_T315_A1.1601.00
250_E253_D1.1601.00
421_K424_D1.1581.00
150_I262_M1.1531.00
44_A48_K1.1481.00
272_A275_K1.1371.00
400_S422_K1.1231.00
75_K78_T1.1181.00
149_G284_F1.1151.00
209_N229_Q1.1091.00
254_A260_A1.1081.00
153_R280_K1.1071.00
174_V262_M1.1071.00
60_I317_K1.0951.00
87_E309_T1.0931.00
345_A348_T1.0891.00
312_T316_E1.0881.00
155_D280_K1.0811.00
326_D329_A1.0801.00
111_A115_S1.0771.00
176_Q242_M1.0751.00
45_V48_K1.0701.00
235_R412_L1.0681.00
169_Q290_K1.0681.00
157_L162_L1.0671.00
156_V185_K1.0661.00
321_F327_N1.0631.00
228_M416_L1.0581.00
401_M422_K1.0571.00
83_G308_K1.0471.00
49_L52_R1.0441.00
180_D183_N1.0411.00
265_Y269_I1.0391.00
85_L306_G1.0371.00
171_L175_A1.0371.00
33_F303_I1.0341.00
29_V59_G1.0321.00
185_K259_T1.0261.00
171_L262_M1.0231.00
356_D359_K1.0231.00
14_S18_I1.0201.00
318_F322_M1.0201.00
21_C24_E1.0191.00
151_W265_Y1.0141.00
18_I21_C1.0131.00
396_G399_S1.0111.00
115_S119_E1.0091.00
48_K334_M1.0081.00
366_N370_G1.0071.00
48_K330_D1.0011.00
88_V319_V0.9961.00
155_D158_A0.9951.00
21_C25_N0.9941.00
156_V159_K0.9931.00
400_S404_N0.9921.00
156_V160_A0.9871.00
397_V401_M0.9861.00
123_Y344_K0.9841.00
183_N186_Y0.9841.00
73_N95_Y0.9801.00
177_K180_D0.9741.00
100_D133_E0.9691.00
112_T115_S0.9571.00
313_E316_E0.9481.00
315_A319_V0.9471.00
76_V89_I0.9471.00
158_A163_E0.9461.00
10_S14_S0.9451.00
367_Q370_G0.9391.00
206_A227_M0.9391.00
119_E127_L0.9381.00
53_F314_A0.9371.00
391_D396_G0.9371.00
50_I62_V0.9281.00
15_C18_I0.9271.00
31_I318_F0.9271.00
117_V120_G0.9241.00
220_I424_D0.9211.00
124_D127_L0.9211.00
125_G128_R0.9201.00
305_A315_A0.9161.00
305_A309_T0.9111.00
171_L188_I0.9111.00
416_L420_Q0.9091.00
89_I304_T0.9091.00
401_M415_T0.9081.00
318_F321_F0.9061.00
88_V318_F0.9061.00
359_K362_G0.9051.00
360_A363_E0.9051.00
121_A343_N0.9011.00
306_G309_T0.9001.00
10_S13_V0.8971.00
240_N243_P0.8971.00
34_M67_V0.8901.00
127_L138_W0.8901.00
10_S16_A0.8881.00
67_V75_K0.8881.00
392_V423_L0.8851.00
52_R326_D0.8841.00
231_L405_V0.8831.00
179_N187_G0.8831.00
143_V303_I0.8831.00
17_L20_G0.8761.00
153_R281_N0.8761.00
117_V320_T0.8741.00
364_L367_Q0.8711.00
326_D330_D0.8711.00
13_V17_L0.8711.00
221_T224_T0.8701.00
344_K348_T0.8691.00
78_T82_S0.8661.00
62_V318_F0.8651.00
80_S104_L0.8631.00
113_V313_E0.8591.00
253_D256_M0.8591.00
220_I420_Q0.8551.00
307_Q312_T0.8521.00
222_L227_M0.8461.00
122_F323_E0.8451.00
59_G317_K0.8421.00
158_A281_N0.8411.00
31_I314_A0.8401.00
241_T245_S0.8401.00
305_A316_E0.8401.00
79_L84_S0.8391.00
329_A346_V0.8381.00
52_R327_N0.8341.00
97_K101_K0.8331.00
49_L327_N0.8241.00
395_S399_S0.8231.00
29_V60_I0.8221.00
388_R391_D0.8211.00
271_P275_K0.8201.00
411_D415_T0.8191.00
56_E321_F0.8181.00
132_T135_G0.8181.00
235_R238_T0.8111.00
130_V138_W0.8081.00
179_N242_M0.8071.00
123_Y126_V0.8071.00
160_A177_K0.8061.00
308_K311_E0.8061.00
152_Y164_E0.8061.00
231_L416_L0.8051.00
9_L12_L0.8011.00
159_K185_K0.7941.00
175_A187_G0.7911.00
174_V178_L0.7901.00
415_T419_S0.7901.00
249_M252_K0.7871.00
372_L375_I0.7871.00
103_Q307_Q0.7851.00
224_T227_M0.7841.00
162_L178_L0.7831.00
163_E166_K0.7811.00
12_L15_C0.7811.00
31_I311_E0.7811.00
98_V102_E0.7771.00
175_A242_M0.7761.00
172_L242_M0.7731.00
416_L419_S0.7731.00
21_C26_K0.7701.00
400_S403_H0.7701.00
140_G304_T0.7631.00
9_L15_C0.7631.00
209_N233_Y0.7611.00
239_A408_G0.7601.00
9_L16_A0.7581.00
397_V419_S0.7561.00
206_A211_A0.7521.00
99_M105_I0.7491.00
329_A349_T0.7491.00
9_L13_V0.7491.00
54_E62_V0.7491.00
364_L368_L0.7471.00
77_I98_V0.7461.00
74_T78_T0.7461.00
224_T228_M0.7451.00
12_L16_A0.7401.00
11_A17_L0.7381.00
234_Y238_T0.7371.00
168_W172_L0.7361.00
361_L364_L0.7351.00
34_M86_P0.7351.00
17_L21_C0.7331.00
415_T418_A0.7321.00
205_F209_N0.7321.00
56_E326_D0.7291.00
370_G373_P0.7281.00
243_P246_N0.7281.00
20_G23_E0.7271.00
112_T136_S0.7271.00
166_K288_T0.7261.00
231_L415_T0.7231.00
100_D105_I0.7231.00
360_A364_L0.7211.00
403_H407_V0.7211.00
190_L193_A0.7201.00
357_V360_A0.7171.00
176_Q179_N0.7171.00
212_N216_A0.7161.00
136_S139_T0.7151.00
309_T313_E0.7151.00
175_A179_N0.7141.00
172_L175_A0.7131.00
215_N221_T0.7101.00
368_L371_E0.7061.00
24_E27_T0.7051.00
65_V79_L0.7051.00
295_Y298_L0.7051.00
109_A139_T0.7041.00
178_L183_N0.7041.00
270_L274_I0.7021.00
111_A138_W0.6971.00
15_C19_S0.6961.00
157_L178_L0.6941.00
105_I139_T0.6941.00
204_Q207_L0.6921.00
34_M65_V0.6891.00
152_Y157_L0.6871.00
249_M253_D0.6831.00
362_G365_P0.6831.00
28_N58_P0.6831.00
33_F88_V0.6831.00
398_V419_S0.6831.00
6_I17_L0.6821.00
72_Y76_V0.6781.00
116_N119_E0.6761.00
168_W233_Y0.6751.00
118_G121_A0.6701.00
356_D360_A0.6701.00
114_I138_W0.6691.00
371_E374_N0.6681.00
89_I105_I0.6671.00
229_Q289_E0.6671.00
317_K321_F0.6631.00
151_W284_F0.6611.00
122_F127_L0.6601.00
202_F206_A0.6591.00
207_L212_N0.6581.00
369_I372_L0.6571.00
176_Q236_D0.6551.00
10_S17_L0.6551.00
160_A185_K0.6551.00
95_Y98_V0.6541.00
155_D258_G0.6541.00
41_E44_A0.6531.00
6_I10_S0.6511.00
320_T324_Q0.6501.00
49_L330_D0.6491.00
250_E254_A0.6491.00
185_K188_I0.6451.00
19_S23_E0.6441.00
6_I9_L0.6421.00
367_Q371_E0.6421.00
365_P368_L0.6411.00
116_N120_G0.6411.00
160_A183_N0.6401.00
8_L12_L0.6401.00
58_P317_K0.6401.00
121_A325_A0.6391.00
211_A227_M0.6381.00
73_N98_V0.6381.00
16_A19_S0.6381.00
288_T294_V0.6351.00
361_L365_P0.6341.00
237_L242_M0.6341.00
115_S118_G0.6321.00
74_T77_I0.6301.00
242_M245_S0.6281.00
19_S22_K0.6271.00
275_K278_D0.6261.00
153_R258_G0.6261.00
113_V312_T0.6261.00
124_D344_K0.6251.00
31_I315_A0.6241.00
256_M276_E0.6241.00
302_T306_G0.6221.00
8_L15_C0.6221.00
116_N320_T0.6211.00
6_I13_V0.6191.00
71_A75_K0.6181.00
222_L423_L0.6181.00
185_K189_A0.6161.00
123_Y347_V0.6161.00
53_F58_P0.6151.00
276_E279_P0.6111.00
254_A257_N0.6101.00
32_E79_L0.6091.00
389_M395_S0.6091.00
163_E174_V0.6091.00
357_V361_L0.6091.00
271_P274_I0.6091.00
61_T64_Q0.6071.00
112_T316_E0.6061.00
11_A14_S0.6051.00
343_N347_V0.6041.00
127_L132_T0.6041.00
28_N60_I0.6031.00
49_L321_F0.6021.00
412_L416_L0.6011.00
252_K256_M0.6001.00
23_E26_K0.5981.00
179_N186_Y0.5981.00
184_K187_G0.5971.00
193_A247_D0.5961.00
349_T353_K0.5961.00
170_Q174_V0.5951.00
342_V346_V0.5951.00
160_A174_V0.5931.00
179_N241_T0.5921.00
160_A164_E0.5921.00
87_E315_A0.5921.00
77_I81_R0.5911.00
65_V86_P0.5901.00
152_Y262_M0.5901.00
101_K134_D0.5901.00
369_I373_P0.5881.00
365_P369_I0.5881.00
56_E317_K0.5871.00
211_A226_E0.5871.00
269_I273_V0.5861.00
18_I22_K0.5851.00
224_T420_Q0.5841.00
405_V410_A0.5841.00
412_L415_T0.5811.00
65_V75_K0.5811.00
97_K133_E0.5811.00
312_T315_A0.5791.00
251_V263_A0.5791.00
88_V303_I0.5781.00
110_V319_V0.5781.00
96_A100_D0.5781.00
90_E303_I0.5771.00
302_T305_A0.5771.00
316_E319_V0.5751.00
32_E87_E0.5741.00
288_T291_N0.5741.00
111_A132_T0.5741.00
301_L304_T0.5741.00
186_Y190_L0.5721.00
46_I49_L0.5711.00
325_A343_N0.5701.00
7_V14_S0.5691.00
206_A230_A0.5681.00
164_E170_Q0.5671.00
344_K347_V0.5671.00
165_P174_V0.5671.00
164_E174_V0.5661.00
150_I264_I0.5641.00
130_V140_G0.5641.00
54_E59_G0.5641.00
404_N415_T0.5641.00
183_N187_G0.5621.00
96_A140_G0.5621.00
151_W270_L0.5611.00
73_N77_I0.5601.00
389_M392_V0.5591.00
7_V11_A0.5581.00
358_I361_L0.5581.00
58_P314_A0.5571.00
33_F90_E0.5571.00
272_A276_E0.5561.00
29_V32_E0.5561.00
8_L11_A0.5561.00
178_L262_M0.5551.00
154_K280_K0.5551.00
85_L308_K0.5531.00
342_V347_V0.5511.00
353_K359_K0.5491.00
80_S306_G0.5491.00
289_E292_S0.5491.00
190_L194_E0.5491.00
219_K424_D0.5481.00
301_L306_G0.5471.00
230_A234_Y0.5461.00
362_G369_I0.5451.00
21_C27_T0.5441.00
54_E60_I0.5431.00
355_N359_K0.5431.00
160_A261_P0.5421.00
118_G320_T0.5421.00
237_L243_P0.5391.00
241_T244_G0.5371.00
205_F230_A0.5371.00
341_P344_K0.5361.00
358_I362_G0.5361.00
92_S95_Y0.5341.00
303_I319_V0.5331.00
303_I322_M0.5311.00
79_L82_S0.5301.00
308_K312_T0.5291.00
91_T99_M0.5291.00
388_R392_V0.5271.00
157_L164_E0.5271.00
206_A209_N0.5251.00
269_I272_A0.5251.00
7_V10_S0.5251.00
404_N408_G0.5251.00
141_V319_V0.5231.00
33_F64_Q0.5211.00
150_I171_L0.5211.00
252_K265_Y0.5211.00
32_E35_H0.5191.00
69_E72_Y0.5171.00
158_A161_G0.5171.00
290_K293_A0.5171.00
47_S64_Q0.5161.00
370_G374_N0.5151.00
45_V49_L0.5151.00
203_S207_L0.5141.00
274_I282_V0.5131.00
200_Q204_Q0.5131.00
189_A254_A0.5121.00
356_D361_L0.5111.00
69_E73_N0.5081.00
164_E285_V0.5071.00
226_E230_A0.5071.00
132_T136_S0.5071.00
119_E132_T0.5061.00
87_E307_Q0.5051.00
169_Q233_Y0.5031.00
402_V406_T0.5031.00
366_N369_I0.5021.00
114_I316_E0.5021.00
339_A342_V0.5001.00
187_G190_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4r2fA 1 0.8884 100 0.165 Contact Map
4r9fA 1 0.8628 100 0.166 Contact Map
3uorA 1 0.8721 100 0.168 Contact Map
4mfiA 1 0.8814 100 0.179 Contact Map
4r6kA 1 0.8907 100 0.201 Contact Map
3vxbA 1 0.8651 100 0.218 Contact Map
4ovjA 1 0.8744 100 0.237 Contact Map
3k01A 1 0.8791 100 0.239 Contact Map
4r6hA 1 0.8674 100 0.24 Contact Map
1eu8A 1 0.8907 100 0.24 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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