DHAR - ECOLI - GREMLIN Contacts

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DHAR - PTS-dependent dihydroxyacetone kinase operon regulatory protein

UniProt:	P76016	Sequences: MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFASIYRRKKAMLTLGQAALEDAWEYMAPRECALFILDETACILSRNGDPQTLQQLSALGFNDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQVLWNWAFCATPLFDSKGRLTGTIALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVISWDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFESQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQTRRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAALAEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDARRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNNKLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPEHLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRKMKQHGIDAGQFKRRV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13902
Length:	639 (573)
Sequences:	834 (708)
Seq/√Len:	29.6

ECOLI - DHAR YGEV HYFR FHLA RTCR TYRR NORR PRPR NTRC GLRR ATOC
BACSU - ACOR YQIR ROCR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
356_E	496_R	5.396	1.00
385_E	434_S	4.729	1.00
374_R	457_D	4.615	1.00
413_E	447_R	4.596	1.00
527_A	531_L	4.547	1.00
603_T	613_L	4.245	1.00
592_E	624_K	4.075	1.00
471_L	476_R	4.027	1.00
512_S	544_Y	3.608	1.00
393_A	435_A	3.388	1.00
599_A	610_M	3.308	1.00
467_D	470_M	3.265	1.00
589_A	627_Q	3.169	1.00
470_M	474_Q	3.167	1.00
616_I	621_L	3.123	1.00
593_K	597_I	3.039	1.00
421_F	463_T	3.003	1.00
337_L	490_I	2.946	1.00
427_Y	465_T	2.928	1.00
527_A	559_I	2.859	1.00
145_F	162_A	2.785	1.00
337_L	364_L	2.765	1.00
524_D	560_R	2.725	1.00
389_D	431_E	2.716	1.00
374_R	458_V	2.702	1.00
385_E	427_Y	2.684	1.00
327_M	334_T	2.619	1.00
400_D	448_L	2.584	0.99
444_V	455_P	2.563	0.99
350_P	462_A	2.537	0.99
225_L	251_L	2.537	0.99
441_K	544_Y	2.533	0.99
182_A	185_V	2.487	0.99
466_A	471_L	2.480	0.99
117_A	147_A	2.478	0.99
404_N	408_R	2.446	0.99
472_V	475_N	2.436	0.99
246_R	250_E	2.406	0.99
152_D	156_R	2.400	0.99
473_E	479_R	2.398	0.99
425_I	428_L	2.390	0.99
178_T	181_I	2.383	0.99
114_G	135_H	2.346	0.99
444_V	453_L	2.338	0.99
186_G	190_L	2.337	0.99
366_Q	370_N	2.328	0.99
462_A	485_L	2.323	0.99
220_D	224_N	2.268	0.99
446_T	453_L	2.208	0.98
362_A	438_Q	2.127	0.98
596_I	610_M	2.124	0.98
173_A	176_P	2.063	0.97
116_C	120_L	2.027	0.97
596_I	616_I	1.988	0.97
186_G	189_L	1.955	0.96
362_A	442_Q	1.940	0.96
526_D	561_V	1.920	0.96
110_E	114_G	1.917	0.96
596_I	624_K	1.909	0.96
145_F	164_A	1.902	0.96
602_V	613_L	1.899	0.96
588_F	595_A	1.895	0.96
175_L	189_L	1.879	0.96
341_G	364_L	1.873	0.95
503_P	506_V	1.866	0.95
334_T	337_L	1.865	0.95
148_T	178_T	1.843	0.95
595_A	599_A	1.842	0.95
114_G	117_A	1.836	0.95
151_F	157_L	1.835	0.95
392_L	432_L	1.831	0.95
356_E	494_P	1.816	0.95
125_G	151_F	1.795	0.94
506_V	523_I	1.782	0.94
546_V	550_L	1.740	0.93
534_C	568_L	1.737	0.93
503_P	532_V	1.736	0.93
425_I	429_A	1.734	0.93
510_L	551_A	1.730	0.93
359_V	460_V	1.727	0.93
480_Q	484_A	1.715	0.93
591_V	595_A	1.704	0.93
174_D	188_L	1.703	0.92
70_P	90_D	1.696	0.92
420_L	460_V	1.673	0.92
54_L	57_G	1.670	0.92
438_Q	480_Q	1.658	0.91
102_F	143_W	1.630	0.91
550_L	559_I	1.610	0.90
507_N	528_L	1.595	0.90
505_L	509_K	1.568	0.89
524_D	558_R	1.562	0.89
110_E	115_T	1.557	0.89
182_A	189_L	1.548	0.88
353_L	593_K	1.548	0.88
445_I	456_I	1.545	0.88
383_N	391_A	1.544	0.88
603_T	610_M	1.543	0.88
102_F	108_C	1.543	0.88
349_F	552_L	1.537	0.88
331_D	500_G	1.536	0.88
592_E	596_I	1.533	0.88
53_M	59_A	1.527	0.88
390_A	393_A	1.526	0.88
354_C	464_T	1.522	0.87
594_E	598_N	1.518	0.87
438_Q	442_Q	1.514	0.87
625_M	630_I	1.512	0.87
325_A	342_R	1.497	0.87
175_L	186_G	1.495	0.86
468_L	477_F	1.494	0.86
530_R	561_V	1.492	0.86
461_I	621_L	1.491	0.86
345_A	459_K	1.486	0.86
185_V	190_L	1.485	0.86
130_T	134_Q	1.470	0.86
393_A	623_R	1.458	0.85
554_S	563_D	1.457	0.85
424_K	480_Q	1.455	0.85
385_E	509_K	1.455	0.85
394_E	401_R	1.454	0.85
437_L	478_S	1.448	0.85
324_F	367_A	1.443	0.84
607_I	618_R	1.443	0.84
588_F	624_K	1.441	0.84
58_Q	86_S	1.435	0.84
425_I	445_I	1.430	0.84
313_M	318_G	1.429	0.84
130_T	135_H	1.429	0.84
426_E	465_T	1.425	0.84
232_A	236_L	1.423	0.84
284_A	287_T	1.416	0.83
412_L	456_I	1.414	0.83
565_P	568_L	1.405	0.83
322_H	366_Q	1.404	0.83
57_G	61_L	1.390	0.82
392_L	435_A	1.389	0.82
412_L	420_L	1.387	0.82
450_A	453_L	1.384	0.82
624_K	628_H	1.379	0.82
171_T	174_D	1.378	0.82
450_A	454_I	1.364	0.81
478_S	484_A	1.363	0.81
411_R	414_L	1.360	0.81
590_E	594_E	1.360	0.81
534_C	537_P	1.347	0.80
597_I	630_I	1.347	0.80
449_D	480_Q	1.345	0.80
343_Q	555_D	1.331	0.79
185_V	189_L	1.326	0.79
588_F	592_E	1.324	0.79
144_A	165_C	1.322	0.79
180_A	184_E	1.320	0.79
259_Q	262_I	1.318	0.79
495_L	543_L	1.316	0.78
114_G	136_F	1.313	0.78
349_F	548_E	1.313	0.78
225_L	387_Y	1.309	0.78
183_R	186_G	1.308	0.78
426_E	464_T	1.304	0.78
309_M	313_M	1.300	0.78
443_G	455_P	1.297	0.77
461_I	616_I	1.296	0.77
349_F	487_A	1.289	0.77
600_A	607_I	1.287	0.77
116_C	119_S	1.282	0.77
438_Q	484_A	1.280	0.76
402_T	484_A	1.279	0.76
173_A	181_I	1.278	0.76
119_S	145_F	1.271	0.76
338_I	342_R	1.269	0.76
105_G	114_G	1.269	0.76
93_T	97_L	1.264	0.76
114_G	134_Q	1.263	0.75
140_L	164_A	1.263	0.75
53_M	57_G	1.258	0.75
523_I	547_I	1.257	0.75
397_I	410_S	1.253	0.75
424_K	463_T	1.249	0.75
412_L	542_E	1.246	0.74
124_S	130_T	1.243	0.74
503_P	528_L	1.230	0.73
117_A	121_A	1.225	0.73
330_D	504_A	1.223	0.73
114_G	127_A	1.221	0.73
134_Q	140_L	1.221	0.73
60_A	67_Y	1.211	0.72
228_I	232_A	1.208	0.72
54_L	59_A	1.206	0.72
427_Y	627_Q	1.201	0.72
114_G	119_S	1.198	0.71
338_I	364_L	1.197	0.71
251_L	353_L	1.190	0.71
362_A	393_A	1.184	0.71
425_I	456_I	1.179	0.70
117_A	135_H	1.178	0.70
426_E	484_A	1.173	0.70
399_G	424_K	1.172	0.70
596_I	599_A	1.168	0.70
83_C	107_Y	1.166	0.69
449_D	478_S	1.164	0.69
114_G	121_A	1.162	0.69
412_L	458_V	1.160	0.69
110_E	119_S	1.157	0.69
409_L	445_I	1.154	0.69
424_K	449_D	1.153	0.69
606_R	618_R	1.153	0.69
610_M	614_L	1.151	0.68
401_R	424_K	1.149	0.68
439_V	442_Q	1.144	0.68
228_I	457_D	1.141	0.68
510_L	559_I	1.138	0.67
110_E	135_H	1.136	0.67
61_L	64_A	1.134	0.67
175_L	185_V	1.133	0.67
438_Q	449_D	1.132	0.67
424_K	484_A	1.131	0.67
550_L	554_S	1.129	0.67
175_L	182_A	1.127	0.67
426_E	480_Q	1.124	0.66
488_F	542_E	1.123	0.66
525_D	529_A	1.122	0.66
478_S	541_F	1.122	0.66
64_A	67_Y	1.122	0.66
621_L	624_K	1.121	0.66
381_A	438_Q	1.121	0.66
108_C	120_L	1.120	0.66
331_D	413_E	1.114	0.66
386_L	395_E	1.113	0.66
460_V	485_L	1.112	0.66
381_A	402_T	1.111	0.66
446_T	450_A	1.109	0.65
423_E	463_T	1.106	0.65
76_F	87_R	1.104	0.65
399_G	402_T	1.103	0.65
240_A	243_S	1.102	0.65
362_A	441_K	1.102	0.65
351_V	368_I	1.101	0.65
389_D	393_A	1.098	0.65
382_V	571_E	1.096	0.64
437_L	480_Q	1.095	0.64
334_T	338_I	1.090	0.64
316_Q	420_L	1.089	0.64
491_T	494_P	1.088	0.64
466_A	482_Y	1.085	0.64
84_I	87_R	1.085	0.64
218_S	417_G	1.084	0.64
174_D	178_T	1.084	0.64
353_L	492_I	1.082	0.63
181_I	185_V	1.082	0.63
108_C	119_S	1.080	0.63
609_E	612_A	1.077	0.63
415_A	458_V	1.071	0.63
347_S	542_E	1.069	0.63
304_H	315_S	1.068	0.62
329_Q	334_T	1.067	0.62
596_I	621_L	1.065	0.62
89_G	117_A	1.059	0.62
617_G	622_W	1.057	0.62
523_I	528_L	1.051	0.61
339_H	342_R	1.049	0.61
598_N	602_V	1.044	0.61
617_G	621_L	1.034	0.60
549_N	552_L	1.034	0.60
163_L	544_Y	1.031	0.60
612_A	626_K	1.031	0.60
502_I	506_V	1.030	0.60
239_D	242_A	1.023	0.59
119_S	135_H	1.022	0.59
116_C	135_H	1.021	0.59
391_A	438_Q	1.020	0.59
89_G	94_L	1.020	0.59
388_G	426_E	1.018	0.59
84_I	116_C	1.016	0.59
438_Q	478_S	1.015	0.58
399_G	403_D	1.015	0.58
228_I	243_S	1.005	0.58
174_D	181_I	1.003	0.58
401_R	480_Q	1.003	0.58
391_A	400_D	1.002	0.57
391_A	397_I	1.001	0.57
470_M	473_E	1.000	0.57
585_S	599_A	0.996	0.57
71_R	90_D	0.994	0.57
607_I	621_L	0.991	0.57
600_A	625_M	0.990	0.57
383_N	428_L	0.989	0.56
385_E	393_A	0.988	0.56
209_L	605_G	0.986	0.56
383_N	437_L	0.983	0.56
367_A	493_P	0.981	0.56
119_S	122_A	0.980	0.56
225_L	514_E	0.979	0.56
620_T	623_R	0.978	0.56
509_K	547_I	0.977	0.56
486_H	595_A	0.976	0.55
326_H	370_N	0.974	0.55
173_A	187_N	0.972	0.55
424_K	478_S	0.971	0.55
320_V	366_Q	0.969	0.55
134_Q	143_W	0.968	0.55
146_C	542_E	0.968	0.55
534_C	565_P	0.968	0.55
362_A	424_K	0.965	0.55
524_D	527_A	0.965	0.55
402_T	426_E	0.964	0.55
616_I	624_K	0.961	0.54
385_E	435_A	0.961	0.54
172_A	175_L	0.957	0.54
426_E	463_T	0.956	0.54
420_L	456_I	0.953	0.54
105_G	618_R	0.952	0.54
121_A	128_V	0.952	0.54
453_L	485_L	0.950	0.53
387_Y	394_E	0.947	0.53
72_E	90_D	0.944	0.53
344_A	412_L	0.940	0.53
120_L	130_T	0.940	0.53
391_A	541_F	0.937	0.52
110_E	136_F	0.936	0.52
458_V	505_L	0.932	0.52
424_K	438_Q	0.931	0.52
394_E	484_A	0.930	0.52
594_E	597_I	0.927	0.52
113_I	137_K	0.925	0.51
119_S	130_T	0.924	0.51
345_A	368_I	0.921	0.51
108_C	162_A	0.920	0.51
82_A	544_Y	0.918	0.51
250_E	364_L	0.918	0.51
486_H	528_L	0.917	0.51
395_E	399_G	0.915	0.51
391_A	394_E	0.914	0.51
357_E	487_A	0.912	0.50
380_I	516_R	0.911	0.50
424_K	465_T	0.909	0.50
329_Q	353_L	0.908	0.50
175_L	190_L	0.907	0.50
136_F	366_Q	0.904	0.50
362_A	407_G	0.902	0.50
394_E	541_F	0.902	0.50
324_F	341_G	0.899	0.49
391_A	465_T	0.897	0.49
61_L	65_W	0.897	0.49
306_V	524_D	0.895	0.49
61_L	67_Y	0.894	0.49
421_F	424_K	0.893	0.49
401_R	438_Q	0.893	0.49
383_N	478_S	0.888	0.49
394_E	480_Q	0.887	0.48
362_A	478_S	0.884	0.48
105_G	116_C	0.883	0.48
610_M	613_L	0.880	0.48
108_C	116_C	0.879	0.48
74_A	97_L	0.877	0.48
506_V	547_I	0.876	0.48
524_D	561_V	0.872	0.47
357_E	484_A	0.871	0.47
118_L	165_C	0.870	0.47
351_V	497_M	0.869	0.47
345_A	420_L	0.868	0.47
294_T	298_S	0.867	0.47
394_E	437_L	0.865	0.47
397_I	449_D	0.862	0.46
328_P	508_N	0.861	0.46
596_I	630_I	0.861	0.46
173_A	188_L	0.861	0.46
309_M	314_T	0.860	0.46
401_R	426_E	0.859	0.46
64_A	181_I	0.857	0.46
586_L	594_E	0.857	0.46
513_L	547_I	0.857	0.46
362_A	484_A	0.856	0.46
65_W	70_P	0.856	0.46
469_A	567_H	0.850	0.46
345_A	542_E	0.850	0.46
327_M	338_I	0.848	0.45
450_A	626_K	0.848	0.45
484_A	541_F	0.847	0.45
530_R	568_L	0.846	0.45
102_F	390_A	0.840	0.45
480_Q	541_F	0.839	0.45
394_E	402_T	0.839	0.45
351_V	359_V	0.838	0.45
383_N	483_Y	0.838	0.45
617_G	623_R	0.837	0.45
150_L	593_K	0.836	0.44
220_D	492_I	0.830	0.44
565_P	569_F	0.829	0.44
58_Q	62_E	0.826	0.44
426_E	478_S	0.826	0.44
383_N	407_G	0.826	0.44
229_N	622_W	0.825	0.44
388_G	450_A	0.824	0.44
357_E	460_V	0.824	0.44
362_A	383_N	0.823	0.43
110_E	116_C	0.822	0.43
61_L	161_I	0.822	0.43
403_D	424_K	0.820	0.43
587_S	590_E	0.819	0.43
219_W	443_G	0.817	0.43
395_E	424_K	0.815	0.43
413_E	454_I	0.815	0.43
204_Q	542_E	0.813	0.43
87_R	98_S	0.813	0.43
391_A	478_S	0.811	0.43
91_P	98_S	0.810	0.42
410_S	449_D	0.810	0.42
391_A	424_K	0.809	0.42
215_G	415_A	0.809	0.42
362_A	449_D	0.808	0.42
392_L	623_R	0.808	0.42
449_D	541_F	0.807	0.42
357_E	438_Q	0.805	0.42
115_T	135_H	0.805	0.42
412_L	439_V	0.805	0.42
61_L	86_S	0.804	0.42
362_A	465_T	0.803	0.42
401_R	484_A	0.801	0.42
362_A	480_Q	0.801	0.42
356_E	368_I	0.801	0.42
101_G	113_I	0.800	0.42
118_L	140_L	0.798	0.42
423_E	449_D	0.798	0.42
600_A	610_M	0.797	0.41
391_A	484_A	0.796	0.41
546_V	626_K	0.795	0.41
175_L	183_R	0.793	0.41
337_L	341_G	0.792	0.41
615_G	618_R	0.791	0.41
411_R	446_T	0.791	0.41
402_T	424_K	0.789	0.41
402_T	463_T	0.788	0.41
534_C	567_H	0.787	0.41
209_L	344_A	0.787	0.41
499_R	503_P	0.787	0.41
166_P	393_A	0.786	0.41
427_Y	484_A	0.785	0.41
90_D	97_L	0.785	0.41
391_A	449_D	0.785	0.41
438_Q	465_T	0.777	0.40
331_D	334_T	0.777	0.40
153_S	357_E	0.774	0.40
89_G	92_Q	0.773	0.40
117_A	605_G	0.772	0.40
451_R	512_S	0.771	0.39
434_S	460_V	0.771	0.39
394_E	438_Q	0.770	0.39
608_Q	618_R	0.769	0.39
424_K	439_V	0.768	0.39
391_A	426_E	0.767	0.39
137_K	140_L	0.767	0.39
373_E	523_I	0.766	0.39
507_N	590_E	0.766	0.39
179_L	182_A	0.766	0.39
510_L	523_I	0.764	0.39
302_L	305_P	0.763	0.39
562_S	590_E	0.762	0.39
396_F	428_L	0.761	0.39
427_Y	623_R	0.761	0.39
119_S	164_A	0.760	0.39
383_N	465_T	0.759	0.39
254_L	327_M	0.759	0.39
87_R	94_L	0.758	0.38
217_I	224_N	0.757	0.38
105_G	119_S	0.757	0.38
388_G	403_D	0.755	0.38
388_G	395_E	0.754	0.38
395_E	403_D	0.753	0.38
382_V	531_L	0.752	0.38
110_E	117_A	0.751	0.38
101_G	137_K	0.751	0.38
482_Y	488_F	0.748	0.38
85_L	104_D	0.748	0.38
120_L	164_A	0.746	0.38
58_Q	70_P	0.746	0.38
105_G	110_E	0.746	0.38
391_A	401_R	0.746	0.38
349_F	488_F	0.745	0.38
320_V	370_N	0.745	0.38
76_F	102_F	0.744	0.37
219_W	299_F	0.743	0.37
311_Q	625_M	0.743	0.37
78_L	84_I	0.743	0.37
445_I	455_P	0.742	0.37
177_L	184_E	0.742	0.37
299_F	302_L	0.741	0.37
284_A	290_P	0.739	0.37
70_P	73_C	0.736	0.37
388_G	427_Y	0.734	0.37
601_Q	629_G	0.734	0.37
383_N	477_F	0.734	0.37
388_G	393_A	0.733	0.37
527_A	617_G	0.732	0.37
357_E	480_Q	0.732	0.37
388_G	391_A	0.731	0.36
393_A	431_E	0.730	0.36
497_M	535_A	0.730	0.36
169_Q	175_L	0.729	0.36
233_A	240_A	0.729	0.36
551_A	559_I	0.729	0.36
608_Q	619_T	0.728	0.36
527_A	550_L	0.728	0.36
93_T	96_Q	0.727	0.36
291_I	628_H	0.725	0.36
346_R	373_E	0.724	0.36
344_A	488_F	0.720	0.36
119_S	162_A	0.719	0.36
170_T	188_L	0.718	0.36
596_I	617_G	0.717	0.35
114_G	122_A	0.716	0.35
423_E	426_E	0.715	0.35
449_D	484_A	0.715	0.35
182_A	500_G	0.714	0.35
391_A	402_T	0.714	0.35
389_D	427_Y	0.714	0.35
225_L	582_L	0.714	0.35
392_L	439_V	0.714	0.35
442_Q	455_P	0.713	0.35
554_S	619_T	0.713	0.35
148_T	182_A	0.712	0.35
354_C	489_E	0.712	0.35
181_I	188_L	0.711	0.35
356_E	437_L	0.710	0.35
383_N	480_Q	0.708	0.35
215_G	630_I	0.708	0.35
603_T	619_T	0.707	0.35
309_M	312_L	0.705	0.35
78_L	82_A	0.705	0.35
508_N	524_D	0.703	0.34
579_A	583_S	0.703	0.34
399_G	480_Q	0.702	0.34
72_E	93_T	0.702	0.34
506_V	509_K	0.702	0.34
173_A	178_T	0.701	0.34
588_F	591_V	0.700	0.34
328_P	487_A	0.700	0.34
210_E	385_E	0.699	0.34
195_L	218_S	0.697	0.34
68_M	382_V	0.695	0.34
53_M	56_L	0.695	0.34
417_G	457_D	0.693	0.34
593_K	624_K	0.693	0.34
399_G	484_A	0.690	0.34
118_L	164_A	0.690	0.34
116_C	162_A	0.690	0.34
352_L	462_A	0.690	0.34
383_N	449_D	0.690	0.34
399_G	407_G	0.689	0.33
402_T	466_A	0.689	0.33
90_D	93_T	0.688	0.33
399_G	426_E	0.686	0.33
232_A	588_F	0.684	0.33
457_D	507_N	0.684	0.33
176_P	188_L	0.684	0.33
213_D	461_I	0.684	0.33
454_I	461_I	0.683	0.33
362_A	401_R	0.682	0.33
465_T	480_Q	0.682	0.33
424_K	541_F	0.681	0.33
82_A	122_A	0.681	0.33
122_A	135_H	0.681	0.33
450_A	521_L	0.681	0.33
215_G	229_N	0.681	0.33
445_I	619_T	0.680	0.33
125_G	236_L	0.679	0.33
388_G	399_G	0.678	0.33
383_N	401_R	0.678	0.33
438_Q	540_D	0.676	0.33
130_T	229_N	0.676	0.33
161_I	628_H	0.676	0.33
163_L	386_L	0.674	0.32
459_K	505_L	0.674	0.32
114_G	618_R	0.674	0.32
369_H	419_T	0.673	0.32
409_L	450_A	0.673	0.32
174_D	177_L	0.673	0.32
305_P	308_Q	0.671	0.32
391_A	403_D	0.671	0.32
54_L	382_V	0.671	0.32
359_V	621_L	0.670	0.32
120_L	128_V	0.670	0.32
97_L	143_W	0.667	0.32
114_G	130_T	0.667	0.32
517_F	552_L	0.667	0.32
423_E	465_T	0.665	0.32
105_G	135_H	0.665	0.32
383_N	424_K	0.664	0.32
434_S	441_K	0.664	0.32
367_A	462_A	0.664	0.32
334_T	341_G	0.663	0.32
102_F	120_L	0.663	0.32
401_R	449_D	0.661	0.32
353_L	364_L	0.660	0.31
506_V	531_L	0.658	0.31
461_I	526_D	0.657	0.31
426_E	438_Q	0.657	0.31
465_T	484_A	0.655	0.31
83_C	118_L	0.655	0.31
205_L	432_L	0.653	0.31
607_I	625_M	0.651	0.31
428_L	443_G	0.650	0.31
606_R	622_W	0.649	0.31
528_L	532_V	0.649	0.31
324_F	327_M	0.648	0.31
425_I	465_T	0.648	0.31
402_T	465_T	0.647	0.31
596_I	614_L	0.646	0.31
402_T	449_D	0.646	0.31
534_C	610_M	0.644	0.30
184_E	191_T	0.642	0.30
402_T	438_Q	0.642	0.30
332_P	507_N	0.642	0.30
417_G	452_R	0.641	0.30
129_K	146_C	0.640	0.30
119_S	143_W	0.640	0.30
353_L	517_F	0.639	0.30
309_M	318_G	0.638	0.30
115_T	119_S	0.638	0.30
403_D	423_E	0.638	0.30
259_Q	382_V	0.637	0.30
438_Q	541_F	0.634	0.30
97_L	140_L	0.632	0.30
542_E	548_E	0.632	0.30
102_F	140_L	0.631	0.30
165_C	171_T	0.631	0.30
332_P	500_G	0.631	0.30
440_I	460_V	0.631	0.30
150_L	185_V	0.630	0.29
595_A	624_K	0.629	0.29
219_W	252_L	0.629	0.29
353_L	503_P	0.626	0.29
427_Y	471_L	0.624	0.29
60_A	71_R	0.624	0.29
410_S	424_K	0.623	0.29
151_F	279_H	0.623	0.29
163_L	428_L	0.622	0.29
362_A	381_A	0.622	0.29
177_L	186_G	0.622	0.29
290_P	341_G	0.622	0.29
122_A	160_T	0.621	0.29
417_G	568_L	0.621	0.29
57_G	64_A	0.621	0.29
258_L	264_Q	0.620	0.29
406_N	559_I	0.619	0.29
379_Y	418_G	0.619	0.29
75_L	248_I	0.617	0.29
404_N	454_I	0.617	0.29
153_S	158_T	0.617	0.29
467_D	613_L	0.615	0.28
387_Y	406_N	0.613	0.28
184_E	188_L	0.613	0.28
174_D	189_L	0.612	0.28
214_D	380_I	0.611	0.28
407_G	437_L	0.611	0.28
383_N	402_T	0.611	0.28
413_E	459_K	0.610	0.28
117_A	120_L	0.610	0.28
540_D	598_N	0.610	0.28
401_R	407_G	0.609	0.28
57_G	60_A	0.609	0.28
397_I	402_T	0.609	0.28
471_L	474_Q	0.608	0.28
188_L	191_T	0.607	0.28
131_M	144_A	0.606	0.28
542_E	567_H	0.605	0.28
347_S	552_L	0.604	0.28
177_L	617_G	0.604	0.28
353_L	514_E	0.604	0.28
147_A	162_A	0.602	0.28
465_T	560_R	0.602	0.28
357_E	424_K	0.600	0.28
130_T	162_A	0.599	0.27
182_A	190_L	0.599	0.27
114_G	128_V	0.598	0.27
403_D	484_A	0.598	0.27
367_A	371_E	0.597	0.27
363_L	368_I	0.597	0.27
491_T	497_M	0.597	0.27
331_D	447_R	0.597	0.27
188_L	460_V	0.595	0.27
301_L	334_T	0.594	0.27
263_K	482_Y	0.594	0.27
385_E	623_R	0.593	0.27
180_A	185_V	0.592	0.27
270_H	273_A	0.591	0.27
219_W	225_L	0.591	0.27
458_V	542_E	0.591	0.27
329_Q	359_V	0.590	0.27
443_G	542_E	0.590	0.27
56_L	68_M	0.589	0.27
331_D	412_L	0.589	0.27
316_Q	526_D	0.585	0.27
90_D	94_L	0.585	0.27
534_C	560_R	0.584	0.27
395_E	437_L	0.583	0.26
125_G	408_R	0.583	0.26
60_A	64_A	0.581	0.26
361_K	480_Q	0.581	0.26
527_A	568_L	0.581	0.26
181_I	190_L	0.580	0.26
194_L	219_W	0.580	0.26
499_R	502_I	0.580	0.26
357_E	478_S	0.579	0.26
59_A	185_V	0.578	0.26
93_T	100_L	0.577	0.26
378_P	432_L	0.577	0.26
324_F	371_E	0.577	0.26
394_E	424_K	0.577	0.26
456_I	514_E	0.576	0.26
291_I	300_I	0.576	0.26
401_R	541_F	0.576	0.26
402_T	480_Q	0.573	0.26
410_S	484_A	0.572	0.26
386_L	391_A	0.572	0.26
53_M	150_L	0.572	0.26
408_R	464_T	0.571	0.26
284_A	524_D	0.569	0.26
453_L	556_N	0.569	0.26
298_S	301_L	0.568	0.26
412_L	509_K	0.567	0.26
404_N	407_G	0.566	0.25
161_I	392_L	0.565	0.25
278_Q	472_V	0.564	0.25
358_G	539_N	0.564	0.25
315_S	564_L	0.564	0.25
165_C	181_I	0.563	0.25
110_E	127_A	0.563	0.25
78_L	118_L	0.562	0.25
324_F	431_E	0.562	0.25
175_L	181_I	0.561	0.25
403_D	463_T	0.561	0.25
324_F	328_P	0.561	0.25
359_V	534_C	0.560	0.25
107_Y	113_I	0.560	0.25
403_D	407_G	0.560	0.25
202_L	205_L	0.559	0.25
339_H	461_I	0.559	0.25
400_D	424_K	0.557	0.25
391_A	480_Q	0.557	0.25
84_I	118_L	0.557	0.25
311_Q	316_Q	0.557	0.25
377_G	413_E	0.556	0.25
140_L	159_G	0.556	0.25
344_A	429_A	0.555	0.25
506_V	535_A	0.554	0.25
334_T	364_L	0.553	0.25
401_R	463_T	0.553	0.25
394_E	399_G	0.552	0.25
320_V	547_I	0.552	0.25
151_F	252_L	0.550	0.24
459_K	509_K	0.549	0.24
119_S	123_I	0.548	0.24
543_L	550_L	0.547	0.24
597_I	625_M	0.547	0.24
442_Q	608_Q	0.547	0.24
382_V	625_M	0.547	0.24
237_R	533_S	0.546	0.24
402_T	428_L	0.546	0.24
77_I	127_A	0.546	0.24
465_T	478_S	0.545	0.24
386_L	541_F	0.544	0.24
383_N	438_Q	0.544	0.24
119_S	134_Q	0.544	0.24
314_T	318_G	0.543	0.24
391_A	410_S	0.542	0.24
379_Y	407_G	0.542	0.24
250_E	526_D	0.542	0.24
503_P	507_N	0.541	0.24
108_C	140_L	0.541	0.24
588_F	599_A	0.540	0.24
327_M	504_A	0.540	0.24
63_D	67_Y	0.540	0.24
124_S	390_A	0.539	0.24
120_L	145_F	0.538	0.24
406_N	428_L	0.538	0.24
357_E	548_E	0.537	0.24
385_E	449_D	0.537	0.24
61_L	188_L	0.534	0.24
387_Y	479_R	0.534	0.24
550_L	563_D	0.532	0.23
273_A	276_E	0.532	0.23
507_N	630_I	0.532	0.23
315_S	318_G	0.531	0.23
305_P	416_H	0.530	0.23
599_A	603_T	0.530	0.23
75_L	230_A	0.529	0.23
401_R	483_Y	0.528	0.23
459_K	610_M	0.527	0.23
177_L	181_I	0.527	0.23
223_G	552_L	0.527	0.23
161_I	263_K	0.526	0.23
410_S	480_Q	0.526	0.23
420_L	516_R	0.525	0.23
130_T	140_L	0.525	0.23
242_A	494_P	0.525	0.23
122_A	164_A	0.525	0.23
58_Q	61_L	0.524	0.23
117_A	162_A	0.524	0.23
605_G	618_R	0.524	0.23
456_I	475_N	0.524	0.23
399_G	465_T	0.523	0.23
105_G	117_A	0.523	0.23
89_G	165_C	0.523	0.23
523_I	559_I	0.522	0.23
121_A	191_T	0.521	0.23
231_Q	234_R	0.521	0.23
303_L	310_R	0.521	0.23
78_L	83_C	0.520	0.23
323_T	326_H	0.520	0.23
609_E	613_L	0.519	0.23
59_A	64_A	0.519	0.23
57_G	72_E	0.518	0.23
382_V	460_V	0.517	0.23
214_D	218_S	0.517	0.23
146_C	366_Q	0.517	0.23
350_P	489_E	0.517	0.23
108_C	145_F	0.516	0.23
412_L	465_T	0.516	0.23
322_H	370_N	0.516	0.23
386_L	437_L	0.516	0.23
502_I	593_K	0.516	0.23
529_A	601_Q	0.516	0.23
427_Y	480_Q	0.516	0.23
395_E	421_F	0.515	0.23
121_A	605_G	0.515	0.23
108_C	122_A	0.514	0.22
135_H	145_F	0.514	0.22
397_I	484_A	0.514	0.22
471_L	549_N	0.513	0.22
219_W	250_E	0.512	0.22
330_D	335_R	0.512	0.22
126_Q	408_R	0.512	0.22
388_G	407_G	0.511	0.22
56_L	545_S	0.511	0.22
337_L	354_C	0.511	0.22
147_A	553_S	0.511	0.22
394_E	478_S	0.510	0.22
202_L	207_A	0.510	0.22
391_A	423_E	0.510	0.22
135_H	143_W	0.510	0.22
54_L	72_E	0.510	0.22
328_P	465_T	0.509	0.22
437_L	483_Y	0.509	0.22
182_A	191_T	0.509	0.22
113_I	140_L	0.508	0.22
588_F	613_L	0.508	0.22
122_A	145_F	0.507	0.22
349_F	545_S	0.507	0.22
507_N	531_L	0.506	0.22
109_A	112_I	0.506	0.22
336_R	376_A	0.506	0.22
399_G	541_F	0.504	0.22
556_N	560_R	0.504	0.22
121_A	142_N	0.504	0.22
105_G	155_G	0.502	0.22
416_H	456_I	0.502	0.22
469_A	625_M	0.501	0.22
362_A	437_L	0.500	0.22
392_L	551_A	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4l4uA	2	0.5524	100	0.492	Contact Map
1ojlA	3	0.4648	100	0.605	Contact Map
3dzdA	2	0.5509	100	0.62	Contact Map
4fwgA	3	0.6088	100	0.728	Contact Map
4qhsA	3	0.3756	100	0.765	Contact Map
4qosA	1	0.3709	100	0.767	Contact Map
1in4A	1	0.421	100	0.782	Contact Map
1hqcA	1	0.4335	100	0.784	Contact Map
1qvrA	3	0.7731	100	0.785	Contact Map
1r6bX	1	0.6385	100	0.789	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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