GREMLIN Database
YCGR - Flagellar brake protein YcgR
UniProt: P76010 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13899
Length: 244 (223)
Sequences: 469 (359)
Seq/√Len: 24.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
188_L211_F4.2031.00
86_V102_T4.0341.00
23_L75_A3.4941.00
187_Q212_R3.2301.00
172_I186_A2.6600.99
50_K104_P2.5220.99
27_A104_P2.5000.99
216_V220_V2.4150.98
189_I210_S2.3990.98
44_L99_A2.3360.98
30_L73_I2.3270.98
56_G100_F2.2400.97
114_R118_R2.2000.97
171_Q183_H2.1730.96
53_L92_S2.1190.96
74_T83_E2.1150.96
127_Y177_G2.0940.96
188_L209_L2.0910.96
112_Q145_D2.0060.94
74_T81_K1.9860.94
10_K210_S1.9480.93
51_L104_P1.9420.93
84_F176_M1.9380.93
71_I100_F1.8890.92
94_Y99_A1.8560.92
189_I234_E1.7780.90
149_G232_E1.7750.90
84_F225_Q1.7440.89
17_L46_I1.7220.88
8_F140_R1.7110.88
41_S73_I1.6970.87
65_V71_I1.6870.87
221_E232_E1.6570.86
118_R150_G1.6060.84
225_Q232_E1.5970.84
177_G233_R1.5900.84
73_I84_F1.5820.83
228_I235_A1.5570.82
111_V122_P1.5500.82
11_Q107_T1.5500.82
148_L224_L1.4980.80
62_N100_F1.4750.79
76_E232_E1.4370.77
84_F119_I1.4310.77
114_R150_G1.4220.76
176_M225_Q1.4200.76
29_P80_A1.4200.76
146_L192_S1.4160.76
12_N23_L1.3990.75
55_F100_F1.3930.75
141_F209_L1.3920.75
43_L172_I1.3700.73
69_Q132_K1.3680.73
56_G62_N1.3500.72
111_V210_S1.3470.72
195_K224_L1.3430.72
54_D100_F1.3410.72
121_A141_F1.3300.71
111_V189_I1.3230.71
119_I176_M1.3080.70
54_D79_G1.3060.70
17_L104_P1.3020.69
177_G210_S1.2910.69
114_R213_F1.2900.69
44_L98_P1.2810.68
30_L190_S1.2780.68
153_A211_F1.2740.68
105_P150_G1.2710.68
148_L221_E1.2700.67
44_L84_F1.2610.67
73_I102_T1.2590.67
58_Q110_F1.2550.67
10_K19_V1.2540.66
79_G221_E1.2520.66
142_R229_F1.2450.66
89_L174_V1.2350.65
134_A224_L1.2330.65
78_Q217_S1.2070.63
90_Q143_L1.2050.63
29_P42_K1.2040.63
143_L151_M1.1930.63
117_F232_E1.1910.62
61_D100_F1.1890.62
80_A112_Q1.1800.62
119_I228_I1.1690.61
147_S150_G1.1680.61
148_L225_Q1.1540.60
210_S233_R1.1440.59
151_M222_R1.1420.59
108_L178_Q1.1410.59
103_V106_P1.1410.59
122_P151_M1.1350.59
175_N191_I1.1350.59
11_Q69_Q1.1320.58
171_Q186_A1.1210.58
182_F220_V1.1200.58
193_E207_P1.1180.57
32_L221_E1.1180.57
46_I50_K1.1170.57
105_P118_R1.1120.57
180_G231_L1.1000.56
173_E183_H1.0980.56
28_I154_L1.0960.56
52_V99_A1.0820.55
89_L92_S1.0580.53
39_L65_V1.0350.52
119_I237_E1.0270.51
169_F178_Q1.0240.51
122_P225_Q1.0240.51
83_E119_I1.0220.51
187_Q214_L1.0180.50
27_A42_K1.0180.50
151_M174_V1.0160.50
15_A153_A1.0120.50
129_C141_F1.0060.50
166_G231_L1.0020.49
83_E109_W0.9950.49
118_R147_S0.9940.49
72_T130_Q0.9940.49
157_T207_P0.9920.49
92_S101_I0.9870.48
44_L52_V0.9870.48
43_L81_K0.9860.48
153_A214_L0.9830.48
100_F121_A0.9820.48
100_F222_R0.9810.48
15_A184_F0.9800.48
18_G21_R0.9790.48
118_R213_F0.9750.47
15_A186_A0.9710.47
165_E191_I0.9650.47
72_T164_Q0.9650.47
46_I178_Q0.9600.46
140_R184_F0.9600.46
11_Q52_V0.9590.46
46_I187_Q0.9510.46
124_H210_S0.9420.45
75_A117_F0.9410.45
134_A232_E0.9350.44
117_F148_L0.9290.44
22_D108_L0.9170.43
218_P221_E0.9170.43
218_P226_R0.9170.43
105_P114_R0.9150.43
40_I197_I0.9120.43
143_L234_E0.9110.43
20_L44_L0.9090.43
146_L184_F0.9050.42
73_I86_V0.9030.42
39_L95_L0.9000.42
55_F58_Q0.9000.42
173_E181_V0.8990.42
146_L198_D0.8970.42
30_L43_L0.8930.42
169_F224_L0.8910.41
44_L54_D0.8880.41
49_D140_R0.8830.41
117_F233_R0.8800.41
142_R155_L0.8760.40
10_K124_H0.8760.40
143_L233_R0.8710.40
123_L196_V0.8630.40
50_K96_Q0.8540.39
115_R233_R0.8490.39
9_L19_V0.8450.38
117_F210_S0.8410.38
32_L79_G0.8390.38
110_F145_D0.8390.38
58_Q61_D0.8330.37
170_A185_D0.8330.37
9_L107_T0.8280.37
151_M186_A0.8250.37
116_Y190_S0.8240.37
85_T96_Q0.8160.36
152_G193_E0.8160.36
44_L94_Y0.8160.36
54_D113_R0.8130.36
33_S72_T0.8110.36
90_Q165_E0.8090.36
129_C143_L0.8020.35
157_T193_E0.7960.35
40_I83_E0.7920.35
10_K189_I0.7920.35
114_R147_S0.7840.34
53_L141_F0.7800.34
52_V92_S0.7800.34
116_Y232_E0.7780.34
191_I214_L0.7690.33
23_L215_N0.7670.33
123_L206_T0.7660.33
145_D150_G0.7650.33
148_L232_E0.7600.33
83_E111_V0.7560.33
186_A211_F0.7550.32
46_I223_Q0.7510.32
89_L191_I0.7480.32
46_I69_Q0.7470.32
65_V230_S0.7450.32
218_P230_S0.7440.32
97_L103_V0.7440.32
100_F180_G0.7430.32
99_A188_L0.7410.32
48_P163_L0.7400.32
49_D224_L0.7380.31
124_H190_S0.7380.31
78_Q152_G0.7360.31
128_F140_R0.7320.31
119_I188_L0.7270.31
102_T129_C0.7250.31
16_V70_H0.7230.30
35_N95_L0.7220.30
152_G225_Q0.7210.30
62_N115_R0.7190.30
145_D178_Q0.7190.30
12_N96_Q0.7130.30
43_L221_E0.7110.30
34_W103_V0.7090.30
13_P103_V0.7060.29
134_A169_F0.7030.29
55_F66_L0.7030.29
34_W69_Q0.7010.29
118_R210_S0.7010.29
155_L209_L0.6980.29
69_Q168_R0.6980.29
88_Q102_T0.6980.29
27_A58_Q0.6980.29
39_L103_V0.6960.29
175_N182_F0.6930.29
46_I168_R0.6930.29
28_I221_E0.6890.28
179_W210_S0.6860.28
41_S121_A0.6850.28
62_N122_P0.6840.28
206_T234_E0.6830.28
143_L231_L0.6820.28
32_L73_I0.6770.28
43_L173_E0.6760.28
25_K171_Q0.6760.28
105_P145_D0.6720.28
13_P23_L0.6720.28
75_A153_A0.6700.27
123_L215_N0.6660.27
53_L176_M0.6660.27
21_R131_T0.6610.27
54_D111_V0.6580.27
97_L156_E0.6580.27
164_Q167_M0.6570.27
127_Y228_I0.6570.27
51_L218_P0.6560.27
90_Q96_Q0.6540.26
155_L159_K0.6540.26
14_L182_F0.6510.26
52_V94_Y0.6460.26
58_Q131_T0.6460.26
93_E163_L0.6410.26
188_L235_A0.6390.26
47_T75_A0.6380.26
78_Q146_L0.6360.26
210_S232_E0.6320.25
60_E138_T0.6320.25
41_S80_A0.6300.25
45_A227_I0.6250.25
80_A210_S0.6220.25
197_I210_S0.6220.25
112_Q117_F0.6210.25
124_H189_I0.6140.24
37_G69_Q0.6130.24
72_T82_V0.6120.24
26_A141_F0.6100.24
30_L61_D0.6080.24
62_N65_V0.6050.24
79_G211_F0.6020.24
69_Q96_Q0.6000.24
100_F133_L0.6000.24
192_S208_R0.5990.24
105_P147_S0.5980.24
11_Q175_N0.5980.24
113_R122_P0.5980.24
139_L153_A0.5920.23
71_I168_R0.5900.23
48_P178_Q0.5900.23
89_L99_A0.5860.23
70_H135_D0.5850.23
10_K80_A0.5840.23
69_Q93_E0.5830.23
153_A196_V0.5830.23
15_A18_G0.5820.23
98_P231_L0.5770.22
12_N211_F0.5710.22
118_R145_D0.5690.22
138_T184_F0.5680.22
132_K138_T0.5680.22
71_I84_F0.5670.22
53_L169_F0.5650.22
16_V186_A0.5630.22
163_L193_E0.5610.22
221_E225_Q0.5600.22
192_S227_I0.5590.22
43_L51_L0.5590.22
93_E215_N0.5560.21
73_I130_Q0.5530.21
30_L63_I0.5530.21
119_I235_A0.5520.21
79_G149_G0.5510.21
62_N126_P0.5510.21
127_Y227_I0.5490.21
47_T63_I0.5470.21
106_P140_R0.5460.21
13_P212_R0.5450.21
65_V195_K0.5430.21
13_P143_L0.5430.21
77_T153_A0.5420.21
191_I209_L0.5410.21
16_V211_F0.5340.20
17_L51_L0.5300.20
16_V212_R0.5290.20
76_E210_S0.5260.20
80_A164_Q0.5240.20
43_L90_Q0.5230.20
179_W226_R0.5210.20
140_R146_L0.5200.20
33_S130_Q0.5180.20
177_G190_S0.5170.20
175_N198_D0.5110.19
71_I190_S0.5080.19
73_I176_M0.5080.19
146_L189_I0.5070.19
11_Q128_F0.5040.19
143_L181_V0.5030.19
78_Q104_P0.5030.19
156_E161_A0.5020.19
11_Q215_N0.5020.19
50_K90_Q0.5010.19
68_A71_I0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3kyfA 2 0.9139 100 0.422 Contact Map
2rdeA 2 0.8607 99.9 0.584 Contact Map
4rt1A 2 0.4385 99.6 0.731 Contact Map
4i86A 1 0.4139 99.3 0.773 Contact Map
1ywuA 1 0.4836 99.1 0.788 Contact Map
4p02A 1 0.8811 99 0.796 Contact Map
2l74A 1 0.4754 99 0.801 Contact Map
3ph1A 3 0.7008 97.5 0.868 Contact Map
3cnrA 1 0.3689 97 0.878 Contact Map
1uwvA 1 0.3852 16.5 0.952 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0084 seconds.