GREMLIN Database
YCGM - Uncharacterized protein YcgM
UniProt: P76004 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13894
Length: 219 (201)
Sequences: 9775 (5869)
Seq/√Len: 414.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
153_N203_D3.7471.00
99_A189_L3.4221.00
147_T159_Q3.2361.00
149_S208_T2.9951.00
151_S156_Q2.9161.00
206_T216_T2.6961.00
85_T88_H2.6591.00
208_T214_L2.6211.00
86_E174_A2.6041.00
168_K171_P2.5391.00
86_E171_P2.5171.00
74_A99_A2.5161.00
156_Q159_Q2.3891.00
71_V150_L2.3121.00
206_T214_L2.3101.00
81_L84_A2.2911.00
81_L92_A2.2861.00
88_H91_K2.2441.00
149_S159_Q2.1941.00
71_V207_V2.1861.00
90_R93_I2.1141.00
147_T210_D2.1091.00
84_A92_A2.0981.00
125_D181_T2.0601.00
151_S206_T2.0541.00
80_T183_K1.9861.00
160_G164_D1.9491.00
204_E216_T1.9091.00
28_K194_D1.8611.00
59_A126_N1.8471.00
80_T184_A1.7791.00
151_S208_T1.7521.00
47_P123_A1.7501.00
147_T161_T1.7311.00
75_V169_I1.6891.00
74_A189_L1.6611.00
86_E168_K1.6431.00
49_T183_K1.6321.00
90_R170_V1.6251.00
152_V157_R1.6241.00
74_A97_G1.6061.00
130_L187_V1.5771.00
145_N161_T1.5431.00
27_A31_K1.5361.00
60_I67_V1.5361.00
149_S156_Q1.5341.00
69_H157_R1.5341.00
74_A187_V1.5211.00
52_C56_Q1.5181.00
99_A128_C1.4591.00
98_V209_F1.4451.00
152_V199_L1.4321.00
45_I119_E1.4181.00
96_Y137_A1.4141.00
97_G131_S1.3551.00
43_L176_M1.3471.00
24_S35_S1.3381.00
145_N163_A1.3321.00
82_R125_D1.3231.00
71_V148_L1.3181.00
102_L199_L1.3141.00
128_C189_L1.2981.00
22_V172_L1.2811.00
79_A92_A1.2701.00
140_T146_T1.2671.00
28_K164_D1.2401.00
19_V128_C1.2201.00
79_A91_K1.2131.00
53_D56_Q1.2101.00
77_I173_I1.1881.00
30_I37_V1.1851.00
17_S183_K1.1851.00
50_A128_C1.1841.00
64_F67_V1.1771.00
52_C126_N1.1491.00
144_Q170_V1.1461.00
144_Q168_K1.1461.00
142_D145_N1.1221.00
119_E123_A1.1191.00
73_L209_F1.1141.00
65_G106_D1.1111.00
20_V176_M1.1071.00
24_S33_M1.0941.00
80_T92_A1.0871.00
64_F106_D1.0831.00
68_H105_R1.0781.00
22_V43_L1.0641.00
167_H171_P1.0571.00
97_G130_L1.0451.00
102_L129_P1.0431.00
82_R181_T1.0401.00
86_E170_V1.0381.00
60_I201_S1.0341.00
77_I182_L1.0201.00
151_S214_L1.0181.00
26_Y190_T1.0151.00
58_L102_L1.0141.00
80_T181_T0.9991.00
136_A139_F0.9891.00
94_A134_I0.9881.00
66_S109_G0.9851.00
40_E110_K0.9831.00
75_V188_V0.9741.00
28_K31_K0.9741.00
141_G211_G0.9621.00
105_R108_Q0.9581.00
99_A130_L0.9561.00
58_L205_L0.9501.00
104_L127_S0.9471.00
85_T174_A0.9451.00
107_V124_F0.9431.00
78_G94_A0.9421.00
73_L162_T0.9421.00
144_Q165_M0.9391.00
174_A178_K0.9291.00
66_S106_D0.9251.00
71_V98_V0.9201.00
55_R216_T0.9131.00
43_L175_Y0.9111.00
146_T162_T0.9081.00
120_K179_F0.8961.00
62_S83_Q0.8881.00
37_V166_I0.8851.00
150_L207_V0.8821.00
55_R215_T0.8811.00
98_V207_V0.8771.00
98_V212_H0.8681.00
154_G206_T0.8601.00
97_G212_H0.8591.00
54_L215_T0.8571.00
29_H105_R0.8541.00
83_Q178_K0.8451.00
18_K125_D0.8381.00
100_L205_L0.8371.00
76_L134_I0.8341.00
171_P174_A0.8281.00
24_S30_I0.8111.00
67_V127_S0.8071.00
58_L126_N0.8041.00
41_P172_L0.8021.00
172_L190_T0.7921.00
124_F127_S0.7911.00
75_V96_Y0.7891.00
38_P167_H0.7881.00
174_A177_S0.7851.00
41_P175_Y0.7831.00
76_L95_G0.7821.00
61_P127_S0.7791.00
69_H197_G0.7791.00
164_D194_D0.7761.00
176_M188_V0.7721.00
115_G120_K0.7661.00
63_D83_Q0.7651.00
20_V45_I0.7641.00
199_L205_L0.7621.00
84_A174_A0.7511.00
175_Y178_K0.7491.00
146_T209_F0.7491.00
36_A39_E0.7471.00
182_L188_V0.7461.00
63_D178_K0.7401.00
154_G204_E0.7401.00
95_G134_I0.7381.00
16_V51_L0.7341.00
35_S109_G0.7301.00
120_K180_F0.7251.00
29_H32_E0.7251.00
130_L189_L0.7241.00
170_V174_A0.7231.00
76_L97_G0.7211.00
151_S154_G0.7161.00
173_I188_V0.7111.00
20_V180_F0.7091.00
135_P212_H0.7081.00
42_V118_W0.7071.00
42_V116_Q0.7051.00
64_F104_L0.7051.00
199_L203_D0.7041.00
102_L126_N0.7011.00
32_E196_V0.7011.00
124_F179_F0.7001.00
76_L187_V0.6991.00
50_A181_T0.6971.00
45_I123_A0.6961.00
200_Q203_D0.6931.00
143_P162_T0.6921.00
73_L169_I0.6891.00
24_S42_V0.6871.00
74_A130_L0.6871.00
152_V205_L0.6831.00
17_S49_T0.6751.00
77_I80_T0.6731.00
24_S28_K0.6720.99
120_K178_K0.6710.99
46_K128_C0.6710.99
133_F212_H0.6710.99
31_K37_V0.6690.99
66_S198_P0.6680.99
160_G194_D0.6670.99
51_L130_L0.6660.99
22_V176_M0.6650.99
172_L188_V0.6640.99
52_C58_L0.6630.99
21_C189_L0.6630.99
19_V51_L0.6630.99
33_M103_T0.6610.99
18_K47_P0.6590.99
80_T84_A0.6570.99
75_V173_I0.6570.99
27_A166_I0.6540.99
100_L207_V0.6530.99
149_S210_D0.6530.99
132_G135_P0.6520.99
96_Y143_P0.6520.99
31_K34_G0.6520.99
29_H196_V0.6520.99
81_L173_I0.6470.99
31_K164_D0.6450.99
61_P124_F0.6400.99
27_A164_D0.6390.99
77_I92_A0.6370.99
18_K48_E0.6350.99
150_L205_L0.6270.99
103_T108_Q0.6260.99
146_T161_T0.6260.99
27_A37_V0.6240.99
12_L97_G0.6220.99
79_A184_A0.6220.99
93_I96_Y0.6190.99
135_P138_E0.6180.99
104_L107_V0.6170.99
141_G146_T0.6140.99
175_Y179_F0.6140.99
165_M172_L0.6110.99
52_C55_R0.6090.99
137_A141_G0.6080.99
22_V25_N0.6010.99
89_V173_I0.6000.99
88_H92_A0.5980.99
73_L96_Y0.5980.99
148_L209_F0.5980.99
148_L160_G0.5920.99
90_R96_Y0.5920.99
49_T125_D0.5890.99
33_M109_G0.5840.99
59_A82_R0.5830.99
60_I200_Q0.5790.99
147_T163_A0.5780.98
89_V174_A0.5740.98
90_R137_A0.5730.98
98_V215_T0.5730.98
85_T92_A0.5690.98
69_H152_V0.5680.98
109_G121_A0.5670.98
81_L85_T0.5650.98
47_P50_A0.5630.98
49_T181_T0.5630.98
102_L205_L0.5620.98
162_T169_I0.5620.98
89_V170_V0.5610.98
41_P167_H0.5610.98
40_E175_Y0.5600.98
23_G26_Y0.5580.98
90_R169_I0.5560.98
17_S48_E0.5510.98
145_N162_T0.5490.98
58_L67_V0.5470.98
81_L177_S0.5460.98
30_I34_G0.5460.98
18_K186_D0.5440.98
58_L127_S0.5430.98
75_V93_I0.5400.98
97_G133_F0.5390.98
76_L94_A0.5390.98
91_K137_A0.5340.97
134_I212_H0.5340.97
161_T164_D0.5320.97
84_A173_I0.5290.97
151_S159_Q0.5270.97
176_M180_F0.5270.97
87_E174_A0.5270.97
120_K175_Y0.5240.97
66_S110_K0.5220.97
146_T210_D0.5210.97
90_R144_Q0.5200.97
29_H68_H0.5190.97
169_I190_T0.5190.97
171_P175_Y0.5170.97
209_F212_H0.5160.97
29_H108_Q0.5150.97
67_V102_L0.5150.97
67_V124_F0.5150.97
67_V104_L0.5140.97
89_V93_I0.5120.97
60_I64_F0.5110.97
23_G29_H0.5100.97
108_Q121_A0.5080.97
23_G42_V0.5050.96
31_K36_A0.5050.96
34_G37_V0.5040.96
144_Q169_I0.5030.96
56_Q126_N0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4dbfA 2 0.9269 100 0.137 Contact Map
3r6oA 2 0.9315 100 0.14 Contact Map
3rr6A 1 0.9635 100 0.143 Contact Map
1wzoA 4 0.9498 100 0.164 Contact Map
1gttA 1 0.9406 100 0.172 Contact Map
2dfuA 2 0.9224 100 0.177 Contact Map
4maqA 2 0.9498 100 0.192 Contact Map
3lzkA 2 0.9817 100 0.195 Contact Map
1sawA 2 0.9269 100 0.196 Contact Map
3s52A 2 0.9909 100 0.21 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0082 seconds.