GREMLIN Database
YCGI - Putative uncharacterized protein YcgI
UniProt: P76000 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13890
Length: 147 (141)
Sequences: 1118 (851)
Seq/√Len: 71.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
80_K103_R4.6131.00
78_V103_R4.1681.00
19_L56_A4.0961.00
22_D53_E3.9551.00
108_Q126_G3.6601.00
52_R82_F3.3751.00
73_W124_G3.0341.00
18_C59_S3.0251.00
49_S81_E2.9721.00
5_H24_A2.7651.00
119_F145_W2.7041.00
50_I83_V2.4601.00
119_F143_V2.4601.00
7_R24_A2.4391.00
53_E106_I2.3331.00
23_V54_L2.3301.00
107_Y129_H2.2921.00
73_W108_Q2.1361.00
22_D77_A2.0631.00
17_W60_Y1.8961.00
24_A53_E1.8961.00
11_R20_R1.8021.00
139_A145_W1.7841.00
36_L40_M1.6571.00
53_E77_A1.6190.99
43_K92_N1.5850.99
35_H39_G1.5550.99
127_Y136_P1.5300.99
35_H38_N1.5200.99
122_H142_G1.5070.99
20_R57_T1.5030.99
26_E79_R1.4530.99
115_F121_G1.4350.99
75_K108_Q1.3750.98
25_A52_R1.3680.98
40_M91_N1.3600.98
24_A77_A1.2870.97
34_Y90_V1.2860.97
19_L58_L1.2810.97
89_K95_N1.2480.97
79_R106_I1.1980.96
108_Q124_G1.1790.95
50_I81_E1.1330.94
86_N91_N1.1270.94
106_I128_S1.1170.94
57_T90_V1.0850.93
122_H131_A1.0740.92
25_A50_I1.0280.91
68_M144_N1.0150.90
17_W45_V1.0090.90
63_R67_G0.9970.89
16_V60_Y0.9950.89
78_V82_F0.9880.89
74_L109_A0.9820.88
33_Y41_E0.9820.88
28_R48_R0.9820.88
5_H60_Y0.9750.88
70_X111_I0.9750.88
45_V48_R0.9740.88
43_K89_K0.9690.88
49_S83_V0.9640.88
52_R109_A0.9600.87
28_R84_D0.9600.87
11_R57_T0.9560.87
85_D97_V0.9500.87
34_Y137_W0.9340.86
40_M77_A0.9290.86
52_R78_V0.9290.86
44_S84_D0.9280.85
22_D36_L0.9210.85
90_V96_F0.9190.85
43_K48_R0.9140.85
76_A107_Y0.9110.84
70_X113_A0.8970.83
104_R128_S0.8920.83
11_R59_S0.8900.83
38_N91_N0.8850.83
73_W140_V0.8730.82
61_N114_S0.8690.81
81_E134_E0.8660.81
49_S147_F0.8610.81
75_K126_G0.8590.81
25_A64_L0.8510.80
81_E85_D0.8390.79
61_N69_E0.8360.79
48_R145_W0.8340.79
35_H41_E0.8320.79
31_R44_S0.8260.78
66_N116_S0.8100.77
68_M116_S0.8100.77
38_N130_G0.8080.77
122_H138_N0.8050.76
6_L10_F0.7950.75
16_V95_N0.7940.75
27_L147_F0.7940.75
64_L67_G0.7840.74
88_V97_V0.7830.74
52_R126_G0.7770.74
12_M20_R0.7760.74
17_W58_L0.7730.73
104_R147_F0.7660.73
41_E63_R0.7660.73
41_E117_S0.7610.72
17_W22_D0.7600.72
19_L109_A0.7590.72
11_R86_N0.7540.71
101_S132_G0.7420.70
54_L92_N0.7360.70
7_R144_N0.7230.68
36_L42_S0.7230.68
111_I131_A0.7200.68
23_V89_K0.7180.68
17_W89_K0.7170.68
29_S75_K0.7130.67
101_S147_F0.7110.67
13_N95_N0.7100.67
122_H144_N0.7030.66
75_K124_G0.6980.66
56_A71_E0.6970.65
14_P17_W0.6940.65
71_E112_K0.6880.64
77_A106_I0.6860.64
46_D68_M0.6830.64
31_R36_L0.6810.64
41_E120_S0.6780.63
124_G140_V0.6770.63
70_X147_F0.6650.62
112_K144_N0.6600.61
57_T77_A0.6600.61
50_I118_T0.6600.61
36_L123_L0.6580.61
34_Y42_S0.6560.61
43_K46_D0.6510.60
8_C138_N0.6500.60
8_C61_N0.6430.59
87_R95_N0.6420.59
23_V77_A0.6410.59
56_A120_S0.6410.59
107_Y125_V0.6390.59
141_A145_W0.6380.59
88_V100_L0.6350.58
95_N135_S0.6250.57
30_L33_Y0.6230.57
71_E104_R0.6190.56
58_L132_G0.6160.56
33_Y117_S0.6130.56
19_L48_R0.6090.55
9_L21_A0.6070.55
57_T71_E0.6060.55
106_I126_G0.6020.54
4_I130_G0.6020.54
30_L141_A0.6020.54
22_D73_W0.6020.54
27_L86_N0.6020.54
22_D42_S0.6000.54
4_I89_K0.5980.54
18_C31_R0.5930.53
109_A132_G0.5920.53
25_A121_G0.5900.53
23_V38_N0.5900.53
116_S141_A0.5880.53
42_S53_E0.5850.52
75_K102_G0.5830.52
4_I74_L0.5770.51
6_L120_S0.5750.51
36_L108_Q0.5750.51
12_M26_E0.5710.50
24_A27_L0.5690.50
48_R87_R0.5680.50
88_V92_N0.5670.50
127_Y134_E0.5560.49
133_V137_W0.5530.48
120_S141_A0.5530.48
95_N141_A0.5530.48
91_N97_V0.5500.48
67_G109_A0.5500.48
77_A96_F0.5490.48
68_M114_S0.5470.48
26_E140_V0.5470.48
53_E79_R0.5450.47
20_R111_I0.5450.47
52_R93_D0.5420.47
52_R80_K0.5390.47
17_W98_N0.5380.46
16_V62_M0.5370.46
10_F32_R0.5370.46
90_V95_N0.5360.46
14_P56_A0.5320.46
50_I107_Y0.5310.46
58_L98_N0.5290.45
66_N125_V0.5290.45
88_V115_F0.5270.45
51_Y84_D0.5250.45
76_A118_T0.5240.45
7_R57_T0.5220.44
19_L62_M0.5190.44
11_R61_N0.5170.44
49_S82_F0.5160.44
59_S145_W0.5130.43
133_V144_N0.5110.43
62_M131_A0.5100.43
10_F16_V0.5090.43
31_R39_G0.5090.43
111_I120_S0.5070.43
116_S119_F0.5070.43
82_F123_L0.5070.43
34_Y44_S0.5060.43
23_V30_L0.5060.43
41_E114_S0.5050.42
4_I92_N0.5040.42
128_S133_V0.5010.42
41_E141_A0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4meeA 1 0.9524 99.9 0.377 Contact Map
3qq2A 2 0.9048 99.9 0.417 Contact Map
3sltA 1 0.9864 99.9 0.454 Contact Map
3aehA 1 0.8163 99.9 0.457 Contact Map
3kvnX 1 0.966 99.9 0.486 Contact Map
1uynX 1 0.8707 99.8 0.506 Contact Map
2jmmA 1 0.8435 98.2 0.779 Contact Map
2x27X 1 0.9524 98.1 0.783 Contact Map
1ormA 1 0.8707 98.1 0.783 Contact Map
2k0lA 1 0.9048 98.1 0.784 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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