GREMLIN Database
YCGG - Uncharacterized protein YcgG
UniProt: P75995 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13888
Length: 507 (411)
Sequences: 18823 (14943)
Seq/√Len: 737.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
280_V492_L4.0131.00
272_G478_Q3.9141.00
314_Q354_E3.4971.00
356_L395_N3.2961.00
313_T345_H3.1831.00
426_H430_G3.0551.00
318_N361_S2.9421.00
104_N108_L2.9281.00
263_V287_K2.9211.00
266_Y323_Q2.9021.00
393_H420_D2.8501.00
245_K298_A2.7991.00
370_V421_Y2.7981.00
484_Y487_V2.7921.00
271_N274_E2.6471.00
328_A368_N2.5881.00
469_Y473_N2.5781.00
170_R173_D2.5621.00
325_N329_S2.5481.00
450_R476_T2.4701.00
464_K468_D2.4241.00
252_I288_Q2.3461.00
467_L483_F2.2521.00
315_S319_Q2.2311.00
323_Q489_Y2.2031.00
400_A421_Y2.1451.00
443_D451_K2.1311.00
288_Q292_G2.1071.00
255_R259_N2.1021.00
133_I206_F2.0961.00
415_H438_S2.0781.00
319_Q322_R2.0631.00
303_A312_L2.0211.00
284_A316_L1.9981.00
461_V478_Q1.9931.00
287_K293_Y1.9711.00
246_S305_K1.9381.00
439_T469_Y1.9301.00
321_A358_F1.9291.00
319_Q323_Q1.9061.00
467_L478_Q1.9011.00
463_T466_Q1.8781.00
135_L202_F1.8751.00
263_V293_Y1.8651.00
443_D473_N1.8561.00
260_G319_Q1.8551.00
269_V477_F1.8531.00
265_F488_T1.8121.00
365_R368_N1.8101.00
213_S216_R1.7641.00
488_T491_D1.7591.00
264_P316_L1.7481.00
269_V421_Y1.7451.00
389_L399_I1.7231.00
324_M364_R1.7211.00
318_N358_F1.7211.00
341_F351_F1.7181.00
370_V400_A1.7161.00
358_F362_F1.7141.00
336_H398_V1.7111.00
433_N439_T1.7061.00
421_Y457_V1.7011.00
140_F201_H1.6941.00
270_V483_F1.6851.00
323_Q327_I1.6751.00
156_G159_N1.6661.00
228_I233_C1.6661.00
467_L471_N1.6621.00
443_D447_D1.6621.00
288_Q291_G1.6411.00
398_V420_D1.6351.00
318_N362_F1.6331.00
146_L154_I1.6261.00
422_I449_A1.6231.00
464_K482_Y1.6041.00
265_F293_Y1.5921.00
467_L482_Y1.5921.00
446_L473_N1.5791.00
433_N465_E1.5651.00
446_L475_I1.5621.00
455_S477_F1.5591.00
269_V370_V1.5561.00
208_P211_L1.5371.00
330_K493_V1.5371.00
455_S476_T1.5331.00
359_R397_F1.5311.00
204_I234_A1.5251.00
336_H370_V1.5211.00
278_R477_F1.5201.00
160_V189_Y1.5201.00
190_P195_V1.5091.00
261_E288_Q1.4991.00
481_Y486_P1.4921.00
327_I489_Y1.4761.00
262_I284_A1.4641.00
95_I98_C1.4481.00
415_H431_R1.4481.00
401_L419_I1.4451.00
160_V163_K1.4331.00
341_F371_L1.4261.00
94_G98_C1.4231.00
357_N361_S1.4171.00
487_V495_I1.4081.00
421_Y455_S1.3911.00
109_S177_G1.3901.00
433_N469_Y1.3761.00
328_A365_R1.3711.00
163_K166_R1.3691.00
269_V279_G1.3631.00
264_P315_S1.3591.00
284_A312_L1.3491.00
326_A330_K1.3481.00
211_L220_K1.3441.00
426_H460_G1.3381.00
157_A198_T1.3351.00
491_D494_K1.3271.00
322_R362_F1.3211.00
386_V390_N1.3041.00
310_V348_S1.3031.00
320_V337_I1.2871.00
356_L391_I1.2871.00
277_L495_I1.2851.00
245_K291_G1.2851.00
432_V469_Y1.2781.00
261_E286_W1.2681.00
95_I99_T1.2551.00
323_Q326_A1.2541.00
156_G192_T1.2531.00
458_A475_I1.2511.00
359_R366_D1.2471.00
449_A456_I1.2451.00
468_D471_N1.2391.00
255_R261_E1.2341.00
386_V416_D1.2321.00
131_L209_P1.2301.00
291_G298_A1.2281.00
354_E358_F1.2241.00
334_G368_N1.2191.00
324_M337_I1.2121.00
252_I291_G1.2081.00
228_I231_I1.2081.00
271_N276_T1.2071.00
284_A315_S1.2021.00
478_Q483_F1.2001.00
160_V164_G1.1951.00
91_L95_I1.1871.00
220_K240_D1.1811.00
141_A144_R1.1791.00
271_N278_R1.1781.00
114_F162_L1.1771.00
272_G467_L1.1751.00
390_N394_E1.1731.00
216_R220_K1.1661.00
352_V356_L1.1611.00
161_P185_L1.1541.00
484_Y495_I1.1531.00
356_L360_D1.1521.00
419_I454_I1.1521.00
144_R250_E1.1511.00
139_Q161_P1.1491.00
468_D472_Q1.1481.00
184_T187_G1.1411.00
205_I220_K1.1381.00
182_V232_A1.1371.00
370_V398_V1.1341.00
464_K467_L1.1291.00
138_N229_L1.1261.00
99_T103_G1.1261.00
275_G471_N1.1261.00
137_Q200_Y1.1221.00
227_F233_C1.1221.00
447_D451_K1.1221.00
269_V338_G1.1131.00
325_N328_A1.1101.00
487_V491_D1.1091.00
355_C371_L1.1021.00
433_N463_T1.1021.00
88_I91_L1.0991.00
435_D438_S1.0981.00
421_Y477_F1.0891.00
432_V442_L1.0871.00
262_I315_S1.0851.00
327_I493_V1.0831.00
248_T252_I1.0831.00
324_M328_A1.0821.00
156_G160_V1.0781.00
98_C101_L1.0771.00
279_G336_H1.0721.00
338_G370_V1.0701.00
347_I380_N1.0691.00
355_C392_L1.0691.00
169_L175_I1.0681.00
343_A376_R1.0661.00
263_V488_T1.0641.00
352_V391_I1.0641.00
107_L118_N1.0431.00
325_N362_F1.0431.00
306_S310_V1.0421.00
185_L200_Y1.0411.00
352_V388_R1.0341.00
210_P234_A1.0271.00
253_L303_A1.0261.00
318_N322_R1.0251.00
321_A369_L1.0241.00
119_L123_P1.0171.00
136_Y225_L1.0161.00
444_C451_K1.0151.00
269_V336_H1.0131.00
269_V457_V1.0091.00
440_R451_K1.0081.00
320_V339_I1.0021.00
132_P207_N1.0021.00
249_P302_L1.0011.00
469_Y472_Q0.9991.00
186_N230_L0.9981.00
384_S388_R0.9891.00
296_P299_F0.9871.00
371_L397_F0.9851.00
297_A426_H0.9831.00
101_L105_R0.9821.00
92_K95_I0.9811.00
240_D244_N0.9791.00
261_E289_P0.9731.00
153_H156_G0.9721.00
446_L456_I0.9721.00
388_R391_I0.9721.00
489_Y493_V0.9711.00
264_P320_V0.9651.00
325_N363_T0.9651.00
311_P314_Q0.9651.00
252_I290_H0.9641.00
139_Q200_Y0.9621.00
270_V495_I0.9621.00
159_N163_K0.9621.00
207_N217_L0.9571.00
199_K230_L0.9541.00
250_E254_R0.9531.00
382_D417_L0.9511.00
260_G315_S0.9461.00
255_R258_N0.9451.00
322_R326_A0.9401.00
457_V477_F0.9351.00
291_G294_I0.9341.00
164_G189_Y0.9331.00
348_S354_E0.9331.00
110_R118_N0.9271.00
391_I394_E0.9251.00
273_R476_T0.9241.00
288_Q294_I0.9201.00
123_P126_D0.9171.00
104_N113_V0.9151.00
169_L173_D0.9141.00
350_T354_E0.9111.00
165_V175_I0.9111.00
280_V335_F0.9101.00
358_F361_S0.9091.00
168_V184_T0.9071.00
146_L155_R0.9051.00
183_M186_N0.9041.00
281_E340_N0.9041.00
101_L104_N0.9031.00
433_N466_Q0.9031.00
308_L311_P0.9031.00
182_V202_F0.9001.00
97_W101_L0.9001.00
271_N476_T0.9001.00
168_V180_G0.8991.00
206_F234_A0.8991.00
260_G318_N0.8991.00
216_R219_D0.8981.00
121_L124_A0.8961.00
387_Q391_I0.8921.00
258_N311_P0.8901.00
152_Q215_Y0.8881.00
94_G97_W0.8861.00
317_M358_F0.8841.00
237_F241_R0.8791.00
264_P282_V0.8771.00
195_V255_R0.8761.00
300_I309_I0.8761.00
323_Q493_V0.8741.00
273_R471_N0.8741.00
353_D391_I0.8711.00
97_W102_P0.8681.00
250_E306_S0.8681.00
223_G239_L0.8671.00
282_V337_I0.8671.00
289_P292_G0.8611.00
430_G466_Q0.8611.00
115_P174_D0.8601.00
253_L262_I0.8581.00
256_A261_E0.8571.00
304_E309_I0.8551.00
351_F355_C0.8511.00
264_P284_A0.8501.00
326_A489_Y0.8491.00
353_D357_N0.8481.00
381_V384_S0.8481.00
266_Y280_V0.8451.00
336_H368_N0.8441.00
321_A364_R0.8411.00
379_L413_Y0.8411.00
256_A262_I0.8381.00
185_L189_Y0.8371.00
93_Q96_V0.8371.00
446_L450_R0.8341.00
203_T224_I0.8331.00
102_P105_R0.8311.00
326_A329_S0.8301.00
153_H194_K0.8291.00
136_Y221_G0.8231.00
141_A250_E0.8221.00
97_W100_S0.8201.00
190_P193_E0.8201.00
266_Y282_V0.8201.00
364_R369_L0.8201.00
87_T90_I0.8191.00
354_E357_N0.8151.00
103_G107_L0.8151.00
96_V100_S0.8151.00
107_L115_P0.8151.00
493_V497_L0.8141.00
314_Q318_N0.8121.00
222_F226_I0.8121.00
135_L204_I0.8111.00
310_V345_H0.8111.00
121_L126_D0.8101.00
145_I154_I0.8101.00
398_V455_S0.8091.00
461_V467_L0.8081.00
284_A299_F0.8081.00
317_M355_C0.8081.00
314_Q358_F0.8071.00
254_R308_L0.8071.00
204_I232_A0.8061.00
143_T147_V0.8041.00
97_W105_R0.8031.00
96_V99_T0.8021.00
236_A239_L0.8001.00
203_T221_G0.7991.00
257_I315_S0.7981.00
447_D450_R0.7911.00
254_R311_P0.7891.00
470_L475_I0.7851.00
167_Y184_T0.7841.00
415_H441_I0.7841.00
275_G467_L0.7831.00
321_A362_F0.7801.00
440_R443_D0.7791.00
250_E302_L0.7791.00
416_D437_E0.7781.00
303_A309_I0.7741.00
461_V470_L0.7731.00
349_P384_S0.7711.00
138_N146_L0.7711.00
386_V418_H0.7701.00
205_I217_L0.7691.00
95_I101_L0.7691.00
372_E423_K0.7681.00
119_L214_F0.7641.00
99_T102_P0.7631.00
140_F199_K0.7631.00
387_Q390_N0.7621.00
450_R456_I0.7611.00
136_Y178_P0.7581.00
384_S387_Q0.7551.00
111_I159_N0.7531.00
91_L94_G0.7511.00
151_D222_F0.7471.00
266_Y489_Y0.7461.00
270_V277_L0.7451.00
268_P484_Y0.7441.00
494_K497_L0.7441.00
306_S309_I0.7431.00
157_A189_Y0.7431.00
382_D386_V0.7421.00
162_L175_I0.7421.00
98_C102_P0.7411.00
390_N418_H0.7391.00
138_N226_I0.7371.00
205_I221_G0.7351.00
429_V432_V0.7341.00
374_T403_D0.7321.00
108_L115_P0.7281.00
439_T443_D0.7271.00
458_A470_L0.7241.00
191_Y196_H0.7241.00
92_K96_V0.7231.00
282_V320_V0.7211.00
137_Q202_F0.7161.00
120_L124_A0.7151.00
142_D146_L0.7131.00
404_F445_V0.7121.00
149_I196_H0.7111.00
431_R438_S0.7091.00
142_D158_L0.7081.00
143_T226_I0.7061.00
328_A334_G0.7061.00
268_P487_V0.7051.00
431_R434_A0.7031.00
140_F230_L0.7021.00
436_P439_T0.6991.00
317_M339_I0.6981.00
429_V458_A0.6951.00
164_G188_H0.6941.00
142_D154_I0.6921.00
153_H191_Y0.6901.00
403_D459_E0.6901.00
268_P277_L0.6891.00
326_A493_V0.6871.00
481_Y485_K0.6871.00
438_S466_Q0.6831.00
126_D212_F0.6831.00
93_Q97_W0.6811.00
149_I194_K0.6811.00
492_L495_I0.6771.00
145_I157_A0.6761.00
309_I344_S0.6731.00
141_A305_K0.6711.00
220_K235_A0.6661.00
170_R180_G0.6661.00
235_A240_D0.6651.00
97_W103_G0.6651.00
265_F287_K0.6641.00
353_D356_L0.6641.00
314_Q357_N0.6631.00
295_S298_A0.6631.00
227_F242_Y0.6611.00
182_V200_Y0.6611.00
297_A301_P0.6611.00
238_L242_Y0.6601.00
487_V492_L0.6581.00
248_T291_G0.6571.00
446_L470_L0.6561.00
287_K292_G0.6521.00
401_L413_Y0.6521.00
346_I377_E0.6521.00
346_I388_R0.6511.00
161_P165_V0.6511.00
238_L241_R0.6511.00
424_I475_I0.6501.00
439_T473_N0.6491.00
253_L308_L0.6481.00
272_G471_N0.6471.00
197_S254_R0.6471.00
280_V337_I0.6451.00
335_F368_N0.6451.00
352_V395_N0.6431.00
382_D385_L0.6431.00
431_R435_D0.6411.00
398_V421_Y0.6411.00
241_R245_K0.6391.00
182_V230_L0.6361.00
201_H228_I0.6361.00
207_N211_L0.6361.00
248_T290_H0.6331.00
235_A239_L0.6321.00
369_L397_F0.6291.00
270_V275_G0.6271.00
90_I95_I0.6271.00
359_R362_F0.6261.00
91_L99_T0.6241.00
456_I476_T0.6241.00
161_P189_Y0.6241.00
244_N248_T0.6231.00
132_P217_L0.6221.00
339_I369_L0.6201.00
462_E481_Y0.6191.00
166_R175_I0.6181.00
188_H195_V0.6181.00
406_T427_S0.6171.00
324_M334_G0.6171.00
324_M368_N0.6161.00
253_L256_A0.6151.00
153_H196_H0.6141.00
275_G464_K0.6121.00
252_I255_R0.6121.00
121_L132_P0.6111.00
318_N354_E0.6101.00
328_A331_L0.6091.00
252_I286_W0.6081.00
87_T91_L0.6081.00
88_I92_K0.6061.00
314_Q345_H0.6041.00
391_I395_N0.6041.00
242_Y246_S0.6021.00
149_I153_H0.6001.00
168_V181_D0.5991.00
343_A377_E0.5991.00
263_V490_I0.5991.00
355_C358_F0.5981.00
324_M369_L0.5961.00
415_H435_D0.5961.00
163_K167_Y0.5961.00
310_V314_Q0.5951.00
337_I364_R0.5951.00
314_Q348_S0.5941.00
243_F247_A0.5941.00
115_P176_I0.5931.00
355_C397_F0.5931.00
422_I454_I0.5931.00
303_A307_G0.5921.00
212_F216_R0.5891.00
111_I155_R0.5881.00
344_S347_I0.5871.00
445_V449_A0.5871.00
441_I445_V0.5851.00
470_L478_Q0.5851.00
429_V442_L0.5851.00
492_L496_I0.5851.00
253_L312_L0.5851.00
140_F231_I0.5851.00
493_V496_I0.5841.00
413_Y416_D0.5841.00
265_F486_P0.5831.00
330_K497_L0.5811.00
406_T428_F0.5801.00
327_I492_L0.5751.00
371_L399_I0.5751.00
146_L158_L0.5741.00
138_N142_D0.5741.00
99_T104_N0.5731.00
359_R364_R0.5701.00
436_P440_R0.5681.00
379_L385_L0.5671.00
117_S155_R0.5641.00
146_L229_L0.5611.00
317_M341_F0.5611.00
340_N423_K0.5601.00
325_N364_R0.5591.00
241_R244_N0.5591.00
364_R368_N0.5581.00
147_V226_I0.5561.00
317_M321_A0.5551.00
152_Q192_T0.5551.00
152_Q219_D0.5541.00
227_F239_L0.5541.00
249_P252_I0.5521.00
92_K98_C0.5521.00
357_N360_D0.5521.00
143_T146_L0.5521.00
389_L418_H0.5511.00
262_I286_W0.5501.00
131_L206_F0.5501.00
109_S112_P0.5491.00
367_L398_V0.5471.00
314_Q350_T0.5471.00
392_L397_F0.5461.00
89_I95_I0.5451.00
283_L340_N0.5441.00
440_R444_C0.5441.00
281_E423_K0.5431.00
260_G322_R0.5431.00
152_Q156_G0.5421.00
312_L316_L0.5421.00
156_G191_Y0.5411.00
350_T353_D0.5411.00
294_I301_P0.5411.00
287_K291_G0.5391.00
399_I420_D0.5381.00
341_F345_H0.5381.00
133_I204_I0.5371.00
415_H437_E0.5361.00
436_P453_S0.5341.00
432_V470_L0.5341.00
351_F354_E0.5331.00
182_V186_N0.5321.00
263_V319_Q0.5321.00
304_E342_S0.5321.00
125_I132_P0.5301.00
247_A251_E0.5281.00
490_I493_V0.5261.00
313_T316_L0.5261.00
388_R392_L0.5261.00
340_N402_D0.5251.00
164_G184_T0.5251.00
465_E468_D0.5241.00
307_G344_S0.5241.00
345_H351_F0.5231.00
444_C448_L0.5231.00
412_S427_S0.5221.00
437_E453_S0.5221.00
413_Y417_L0.5211.00
276_T333_E0.5211.00
233_C239_L0.5201.00
449_A454_I0.5191.00
332_P335_F0.5181.00
134_L221_G0.5181.00
248_T251_E0.5171.00
275_G483_F0.5161.00
151_D154_I0.5161.00
483_F486_P0.5151.00
343_A413_Y0.5131.00
382_D416_D0.5131.00
206_F209_P0.5091.00
390_N393_H0.5091.00
374_T459_E0.5081.00
245_K249_P0.5081.00
279_G338_G0.5081.00
257_I312_L0.5081.00
448_L452_L0.5071.00
442_L458_A0.5071.00
281_E402_D0.5071.00
134_L218_I0.5061.00
95_I102_P0.5051.00
264_P319_Q0.5041.00
383_E416_D0.5041.00
191_Y194_K0.5041.00
90_I101_L0.5041.00
104_N107_L0.5031.00
210_P220_K0.5021.00
111_I146_L0.5021.00
91_L98_C0.5010.99
277_L484_Y0.5010.99
100_S105_R0.5000.99
245_K248_T0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rnhA 2 0.7633 100 0.209 Contact Map
4j40A 2 0.4951 100 0.232 Contact Map
3pjxA 1 0.7653 100 0.252 Contact Map
4hjfA 1 0.5148 100 0.353 Contact Map
3gfzA 2 0.7239 100 0.373 Contact Map
4kieA 1 0.5148 100 0.425 Contact Map
4hu4A 1 0.4872 100 0.435 Contact Map
2r6oA 2 0.5069 100 0.437 Contact Map
4rniA 2 0.501 100 0.438 Contact Map
3sy8A 6 0.7771 100 0.442 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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