GREMLIN Database
BEEE - Putative protein BeeE from lambdoid prophage e14 region
UniProt: P75980 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14253
Length: 157 (135)
Sequences: 901 (712)
Seq/√Len: 61.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
60_G97_Q3.5331.00
99_F115_A3.4861.00
55_L108_C3.0661.00
103_V115_A3.0241.00
68_H75_Q2.8811.00
135_V149_D2.7441.00
70_N73_L2.5321.00
93_Y139_L2.4451.00
118_V126_E2.3881.00
96_P100_W2.3451.00
107_L113_F2.2701.00
110_R133_G2.2681.00
130_V149_D2.2331.00
53_R57_E2.1801.00
117_K124_V2.1761.00
65_N76_R2.1261.00
117_K127_L2.0461.00
52_V109_L2.0441.00
70_N75_Q2.0371.00
91_N94_M1.9071.00
114_Y137_Y1.8711.00
83_H87_S1.8681.00
138_A146_P1.8471.00
48_V109_L1.7981.00
100_W104_V1.7951.00
55_L104_V1.7460.99
42_A48_V1.7150.99
115_A127_L1.6900.99
102_L106_C1.6530.99
140_G146_P1.6340.99
103_V113_F1.5970.99
77_A83_H1.5910.99
82_L124_V1.5910.99
17_T20_E1.4070.97
114_Y132_P1.3970.97
106_C129_P1.3830.97
104_V107_L1.3740.97
87_S96_P1.3590.97
90_P99_F1.3580.97
58_S61_M1.3530.97
93_Y100_W1.3470.97
136_V150_R1.3380.96
60_G101_E1.2890.95
50_S53_R1.2880.95
136_V148_G1.2760.95
37_I41_R1.2610.95
118_V128_L1.2570.95
106_C132_P1.2460.95
94_M98_E1.2020.93
47_A51_C1.2010.93
92_G128_L1.2000.93
57_E101_E1.1820.93
116_Y130_V1.1810.93
90_P95_T1.1460.92
31_T34_G1.1440.92
140_G144_R1.1410.92
94_M102_L1.1350.91
16_T20_E1.1150.91
119_K124_V1.1110.90
66_L82_L1.1100.90
25_I76_R1.0850.89
48_V51_C1.0810.89
99_F127_L1.0790.89
138_A148_G1.0710.89
78_T83_H1.0690.89
131_D134_C1.0570.88
77_A80_E1.0390.87
69_L78_T1.0080.86
56_A67_Y1.0000.85
33_T37_I0.9890.84
68_H79_G0.9890.84
64_C86_I0.9710.83
20_E24_A0.9490.82
61_M139_L0.9480.82
98_E101_E0.9460.82
15_V21_L0.9430.82
25_I79_G0.9410.81
104_V108_C0.9320.81
67_Y76_R0.9050.79
21_L25_I0.9020.79
97_Q104_V0.8940.78
94_M129_P0.8880.77
46_T50_S0.8780.77
66_L98_E0.8700.76
67_Y74_K0.8690.76
84_K88_T0.8620.75
100_W103_V0.8480.74
110_R132_P0.8440.74
98_E102_L0.8410.73
91_N99_F0.8380.73
17_T22_A0.8100.71
131_D135_V0.8070.70
17_T21_L0.8020.70
84_K89_H0.7970.69
38_S41_R0.7940.69
102_L129_P0.7880.69
49_F93_Y0.7850.68
15_V20_E0.7670.66
58_S62_L0.7670.66
53_R101_E0.7650.66
114_Y135_V0.7580.66
22_A26_G0.7360.63
51_C117_K0.7280.62
43_M54_V0.7250.62
34_G132_P0.7140.61
20_E23_D0.6980.59
61_M89_H0.6940.59
17_T23_D0.6930.59
126_E134_C0.6930.59
110_R131_D0.6920.58
54_V106_C0.6850.58
48_V52_V0.6840.58
61_M97_Q0.6830.57
134_C149_D0.6800.57
47_A58_S0.6750.57
53_R90_P0.6740.56
95_T98_E0.6660.56
84_K87_S0.6550.54
143_Q151_R0.6520.54
112_N135_V0.6510.54
34_G129_P0.6460.53
19_A23_D0.6440.53
83_H86_I0.6390.53
64_C100_W0.6380.52
112_N132_P0.6380.52
68_H71_G0.6260.51
55_L96_P0.6220.51
59_V84_K0.6200.50
63_P67_Y0.6140.50
72_S84_K0.6130.50
37_I42_A0.6090.49
45_L109_L0.6090.49
80_E113_F0.6080.49
56_A105_T0.6070.49
15_V56_A0.6070.49
43_M148_G0.6030.48
99_F103_V0.6020.48
37_I43_M0.5980.48
50_S60_G0.5980.48
105_T146_P0.5970.48
65_N83_H0.5940.47
79_G150_R0.5930.47
26_G100_W0.5910.47
66_L87_S0.5860.47
50_S55_L0.5850.46
71_G79_G0.5830.46
66_L77_A0.5790.46
52_V141_R0.5760.45
30_D41_R0.5720.45
120_A144_R0.5710.45
83_H88_T0.5710.45
52_V105_T0.5700.45
35_K89_H0.5680.45
21_L103_V0.5670.44
15_V18_P0.5670.44
66_L80_E0.5670.44
47_A52_V0.5660.44
53_R107_L0.5650.44
108_C129_P0.5620.44
16_T21_L0.5570.43
68_H122_G0.5550.43
35_K126_E0.5530.43
47_A60_G0.5530.43
61_M146_P0.5510.43
120_A141_R0.5460.42
121_F125_A0.5440.42
54_V57_E0.5440.42
60_G115_A0.5400.41
120_A125_A0.5360.41
23_D44_R0.5360.41
76_R83_H0.5360.41
38_S151_R0.5360.41
51_C95_T0.5330.41
121_F128_L0.5280.40
64_C77_A0.5270.40
143_Q152_E0.5270.40
89_H119_K0.5260.40
65_N87_S0.5260.40
58_S85_L0.5260.40
85_L124_V0.5260.40
78_T89_H0.5220.39
47_A64_C0.5210.39
98_E108_C0.5190.39
130_V135_V0.5180.39
99_F113_F0.5180.39
59_V62_L0.5180.39
60_G87_S0.5170.39
77_A87_S0.5140.39
134_C150_R0.5140.39
79_G117_K0.5120.38
137_Y152_E0.5120.38
58_S143_Q0.5090.38
22_A59_V0.5090.38
100_W106_C0.5080.38
82_L96_P0.5070.38
34_G41_R0.5070.38
21_L89_H0.5060.38
30_D79_G0.5040.38
42_A54_V0.5020.37
46_T57_E0.5020.37
60_G114_Y0.5000.37
69_L84_K0.5000.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3kdrA 5 0.7006 99.9 0.493 Contact Map
4zjnA 3 0.9427 33 0.933 Contact Map
1hr0W 1 0.3567 11.6 0.946 Contact Map
4ql5A 4 0.3376 10.4 0.947 Contact Map
2rkhA 2 0.4331 8.5 0.949 Contact Map
3t9yA 2 0.586 5.7 0.953 Contact Map
3i4oA 1 0.3376 5.4 0.953 Contact Map
1ah9A 1 0.414 4.9 0.954 Contact Map
2fyuK 1 0.3248 4.1 0.956 Contact Map
4rohA 4 0.1783 4 0.956 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0065 seconds.