GREMLIN Database
FLGA - Flagella basal body P-ring formation protein FlgA
UniProt: P75933 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG20263
Length: 219 (207)
Sequences: 1311 (1059)
Seq/√Len: 73.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
104_I141_S5.9861.00
102_M114_N3.9301.00
57_C80_C3.6191.00
100_A145_L3.4721.00
161_R191_V3.4511.00
98_V117_L3.3131.00
189_A195_A3.2911.00
170_V183_G3.2211.00
197_V215_I3.1261.00
207_G215_I2.9391.00
97_Y120_G2.7901.00
189_A209_V2.7881.00
141_S145_L2.7561.00
100_A104_I2.3171.00
173_S216_L2.3091.00
101_A116_K2.2751.00
130_V136_L2.2011.00
210_D216_L2.1681.00
132_D135_Q2.1401.00
186_L204_V2.0891.00
29_H33_S2.0741.00
105_A108_G2.0241.00
183_G197_V2.0061.00
110_L141_S1.9531.00
136_L156_F1.8961.00
92_Q121_R1.8241.00
104_I110_L1.7901.00
98_V115_V1.7821.00
170_V205_V1.7801.00
111_E114_N1.7361.00
170_V207_G1.7341.00
172_A179_A1.7261.00
211_A214_N1.7251.00
48_R51_P1.6651.00
184_Q199_M1.6581.00
98_V136_L1.5670.99
98_V130_V1.5410.99
184_Q198_R1.5310.99
171_I214_N1.4980.99
102_M108_G1.4950.99
44_R92_Q1.4940.99
160_W188_N1.4800.99
74_V89_V1.4790.99
142_L164_A1.4630.99
185_A195_A1.4240.99
167_R182_E1.3920.98
94_T119_R1.3920.98
198_R202_G1.3760.98
114_N138_D1.3760.98
161_R209_V1.3730.98
162_V195_A1.3650.98
96_N117_L1.3630.98
25_T29_H1.3210.98
189_A193_Q1.3180.98
168_V183_G1.3180.98
98_V133_I1.3070.98
210_D214_N1.2830.97
142_L157_R1.2690.97
96_N119_R1.2680.97
100_A151_I1.2650.97
162_V209_V1.2530.97
166_Q206_S1.2520.97
146_S149_Q1.2470.97
173_S178_S1.2460.97
13_I16_S1.2240.96
187_N195_A1.2010.96
19_S23_N1.1920.96
114_N137_V1.1750.96
57_C172_A1.1730.95
64_M77_L1.1530.95
42_E119_R1.1530.95
166_Q213_G1.1390.95
117_L133_I1.1310.95
138_D183_G1.1240.94
174_G177_F1.1220.94
115_V137_V1.1120.94
77_L86_Y1.1070.94
208_V216_L1.1020.94
46_S51_P1.0950.93
97_Y125_L1.0640.92
196_R206_S1.0630.92
186_L198_R1.0600.92
196_R204_V1.0560.92
128_R152_Q1.0560.92
139_A142_L1.0480.92
32_F89_V1.0470.92
108_G141_S1.0430.92
168_V185_A1.0290.91
93_A122_L1.0270.91
106_R144_D1.0210.91
20_T23_N1.0210.91
80_C86_Y1.0130.91
104_I145_L1.0090.90
195_A209_V1.0050.90
163_K166_Q1.0050.90
63_S76_V1.0010.90
168_V215_I1.0000.90
31_F76_V0.9990.90
160_W163_K0.9890.89
115_V133_I0.9880.89
22_S25_T0.9810.89
99_V118_K0.9780.89
26_S29_H0.9740.89
12_A19_S0.9690.88
143_R196_R0.9630.88
11_I16_S0.9580.88
139_A159_A0.9540.88
103_P147_P0.9540.88
11_I17_P0.9530.88
169_N214_N0.9490.87
164_A187_N0.9390.87
95_G122_L0.9320.86
110_L137_V0.9230.86
101_A110_L0.9090.85
11_I14_L0.9090.85
57_C60_P0.9060.85
141_S144_D0.9010.85
32_F197_V0.9000.84
24_L27_Q0.8990.84
160_W190_A0.8920.84
28_L87_L0.8900.84
139_A158_Q0.8890.84
115_V136_L0.8870.84
164_A188_N0.8800.83
142_L160_W0.8700.82
142_L193_Q0.8690.82
75_N86_Y0.8690.82
161_R189_A0.8670.82
115_V138_D0.8610.82
104_I151_I0.8590.82
190_A193_Q0.8550.81
86_Y91_V0.8450.81
112_A137_V0.8440.80
145_L155_Q0.8380.80
16_S21_A0.8360.80
108_G114_N0.8310.79
97_Y150_P0.8240.79
169_N180_N0.8210.79
183_G205_V0.8120.78
128_R153_L0.8120.78
87_L211_A0.8090.78
170_V199_M0.8090.78
26_S33_S0.8030.77
188_N209_V0.8000.77
136_L151_I0.7980.77
103_P146_S0.7970.77
111_E137_V0.7950.76
140_I157_R0.7940.76
30_N110_L0.7930.76
70_L179_A0.7900.76
171_I216_L0.7900.76
14_L19_S0.7900.76
183_G201_S0.7880.76
32_F37_A0.7790.75
70_L91_V0.7790.75
53_L86_Y0.7790.75
80_C89_V0.7780.75
57_C89_V0.7770.75
72_G91_V0.7760.75
89_V98_V0.7710.74
14_L17_P0.7700.74
21_A25_T0.7670.74
24_L78_A0.7640.73
179_A203_Q0.7620.73
139_A164_A0.7570.73
19_S54_L0.7520.72
99_V116_K0.7490.72
112_A133_I0.7480.72
100_A155_Q0.7470.72
187_N196_R0.7440.71
103_P144_D0.7410.71
62_L79_R0.7340.70
118_K148_D0.7340.70
63_S77_L0.7330.70
32_F36_L0.7240.69
156_F193_Q0.7210.69
19_S80_C0.7200.69
74_V172_A0.7160.69
163_K188_N0.7160.69
198_R204_V0.7150.68
140_I159_A0.7140.68
189_A207_G0.7130.68
90_N198_R0.7110.68
19_S57_C0.7060.67
80_C172_A0.7020.67
106_R187_N0.7010.67
101_A115_V0.7000.67
71_W164_A0.7000.67
120_G125_L0.6970.66
207_G212_D0.6960.66
49_T52_N0.6940.66
55_P165_G0.6940.66
12_A17_P0.6940.66
159_A183_G0.6910.66
60_P80_C0.6900.66
28_L214_N0.6890.66
191_V211_A0.6870.65
41_D151_I0.6860.65
191_V209_V0.6850.65
75_N217_I0.6840.65
140_I160_W0.6810.65
107_G141_S0.6780.64
126_P142_L0.6780.64
50_A53_L0.6770.64
17_P30_N0.6760.64
57_C86_Y0.6650.63
108_G158_Q0.6650.63
161_R190_A0.6610.62
17_P34_A0.6560.62
58_E82_N0.6530.61
162_V166_Q0.6460.61
183_G215_I0.6460.61
95_G179_A0.6450.61
110_L156_F0.6430.60
26_S30_N0.6420.60
106_R157_R0.6420.60
155_Q193_Q0.6410.60
99_V153_L0.6410.60
193_Q200_V0.6340.59
138_D168_V0.6300.59
82_N110_L0.6260.58
47_I51_P0.6210.58
19_S24_L0.6210.58
57_C177_F0.6190.57
200_V203_Q0.6180.57
162_V207_G0.6160.57
105_A144_D0.6120.57
75_N91_V0.6110.56
94_T121_R0.6100.56
57_C82_N0.6100.56
172_A207_G0.6090.56
107_G140_I0.6080.56
11_I34_A0.6060.56
49_T110_L0.6030.55
52_N151_I0.6020.55
146_S158_Q0.6010.55
45_V158_Q0.6010.55
156_F177_F0.6010.55
28_L63_S0.6000.55
12_A15_F0.5980.55
194_N206_S0.5970.55
149_Q162_V0.5940.54
127_P153_L0.5930.54
76_V163_K0.5920.54
189_A210_D0.5920.54
103_P203_Q0.5890.54
166_Q194_N0.5840.53
167_R184_Q0.5840.53
57_C202_G0.5800.53
106_R164_A0.5790.52
23_N27_Q0.5760.52
64_M79_R0.5730.52
88_Q95_G0.5700.51
105_A134_N0.5700.51
61_L170_V0.5700.51
171_I178_S0.5700.51
96_N101_A0.5680.51
26_S150_P0.5670.51
142_L158_Q0.5670.51
54_L90_N0.5640.51
179_A217_I0.5620.50
20_T24_L0.5610.50
200_V208_V0.5600.50
207_G211_A0.5600.50
172_A181_A0.5590.50
98_V104_I0.5590.50
122_L126_P0.5580.50
161_R212_D0.5570.50
99_V115_V0.5560.50
24_L34_A0.5550.49
182_E195_A0.5520.49
59_Q205_V0.5490.49
99_V120_G0.5490.49
80_C202_G0.5480.49
24_L113_G0.5460.48
110_L210_D0.5460.48
48_R52_N0.5450.48
126_P129_T0.5430.48
35_Q63_S0.5430.48
37_A207_G0.5420.48
144_D198_R0.5420.48
31_F205_V0.5380.47
108_G147_P0.5360.47
78_A87_L0.5320.47
159_A162_V0.5310.46
108_G151_I0.5300.46
78_A192_A0.5280.46
136_L152_Q0.5280.46
114_N202_G0.5270.46
95_G174_G0.5250.46
120_G177_F0.5230.45
179_A192_A0.5220.45
100_A175_D0.5180.45
116_K208_V0.5150.45
143_R200_V0.5140.44
112_A171_I0.5130.44
68_S90_N0.5100.44
76_V88_Q0.5080.44
76_V121_R0.5080.44
124_T199_M0.5070.44
155_Q170_V0.5050.43
72_G122_L0.5050.43
145_L190_A0.5040.43
121_R202_G0.5040.43
179_A200_V0.5030.43
106_R217_I0.5010.43
144_D179_A0.5010.43
30_N209_V0.5010.43
69_R104_I0.5000.43
177_F190_A0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3teeA 1 0.8858 100 0.172 Contact Map
3frnA 1 0.9224 100 0.285 Contact Map
4ur6A 2 0.2922 98.6 0.784 Contact Map
1msiA 1 0.3014 98.2 0.803 Contact Map
1ucsA 1 0.2922 97.9 0.818 Contact Map
1wvoA 1 0.3607 97.5 0.833 Contact Map
1c89A 1 0.5845 96.7 0.853 Contact Map
2wqpA 2 0.6575 95.9 0.864 Contact Map
1vliA 2 0.6804 93.1 0.882 Contact Map
3g8rA 2 0.6849 92.2 0.886 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0074 seconds.