GREMLIN Database
PGAB - Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase
UniProt: P75906 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13864
Length: 672 (619)
Sequences: 168 (108)
Seq/√Len: 4.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
92_A96_E6.0500.99
368_V449_L5.1430.96
374_L448_M4.3350.90
125_F173_V3.6710.80
141_G186_W3.4120.75
215_R221_E3.3260.73
317_M343_V3.2910.72
89_V94_I3.1820.69
52_I485_Q3.1690.69
49_F287_I3.0680.66
609_Q613_W3.0630.66
153_K156_D3.0510.66
403_V518_T2.9470.63
360_D366_K2.9450.63
359_P378_K2.9220.62
601_K639_V2.8550.60
210_F221_E2.8370.60
576_E609_Q2.7890.58
187_N223_R2.7520.57
320_D466_D2.7480.57
53_S112_T2.7290.57
192_I208_A2.7250.57
91_I247_V2.7220.56
199_S384_R2.6790.55
652_N655_E2.6210.53
483_A487_A2.6040.53
57_V124_V2.6030.53
624_S658_L2.5920.53
552_W576_E2.5760.52
373_R448_M2.5670.52
74_L78_F2.5610.52
218_T539_I2.5390.51
552_W575_L2.5120.50
89_V520_E2.5060.50
128_L135_A2.4020.47
57_V457_A2.3210.44
316_I643_G2.2830.43
128_L361_G2.2020.41
576_E613_W2.1670.40
129_Q222_Y2.1490.39
155_G648_N2.1420.39
118_Q169_Q2.1300.39
550_E556_N2.1250.39
558_A597_I2.1210.39
187_N190_Y2.1130.38
570_M613_W2.0960.38
496_I499_N2.0900.38
49_F533_I2.0800.37
592_N637_N2.0530.37
538_N613_W2.0240.36
329_L381_I2.0090.35
187_N585_Q2.0050.35
447_G524_R2.0040.35
182_A511_S1.9890.35
368_V406_W1.9710.34
415_V419_P1.9630.34
235_E622_I1.9460.34
374_L445_Q1.9420.34
52_I534_K1.9410.34
226_I259_A1.9330.33
90_S540_F1.9120.33
444_A448_M1.9040.33
222_Y259_A1.9030.33
570_M609_Q1.8980.32
77_Q154_F1.8940.32
317_M346_M1.8590.31
336_I384_R1.8510.31
482_T485_Q1.8510.31
567_T659_I1.8410.31
490_S502_Q1.8250.30
323_Y465_H1.8000.30
144_V247_V1.7980.30
562_K612_N1.7870.30
120_F137_W1.7790.29
469_L540_F1.7780.29
57_V82_R1.7760.29
320_D335_N1.7750.29
185_T204_Y1.7700.29
389_L586_W1.7440.28
385_V652_N1.7350.28
464_F522_S1.7300.28
222_Y522_S1.7060.28
279_A487_A1.7050.28
373_R451_E1.6950.27
69_V207_R1.6930.27
129_Q603_K1.6920.27
317_M531_P1.6910.27
179_V398_Y1.6830.27
406_W449_L1.6770.27
56_N88_P1.6740.27
295_N439_D1.6640.27
79_A131_F1.6640.27
481_I489_F1.6630.27
593_Q648_N1.6570.26
194_A206_N1.6480.26
478_A526_K1.6410.26
314_Q352_Y1.6390.26
255_A360_D1.6290.26
93_Q102_K1.6270.26
476_A497_R1.6260.26
56_N586_W1.6260.26
210_F213_H1.6220.26
54_W552_W1.6130.25
570_M576_E1.6130.25
318_H401_M1.6100.25
201_L383_S1.6080.25
78_F496_I1.6020.25
74_L389_L1.6000.25
315_R586_W1.5970.25
262_E643_G1.5840.25
377_M446_V1.5830.25
360_D365_V1.5800.25
142_S226_I1.5740.24
182_A281_A1.5660.24
527_A567_T1.5650.24
100_G246_H1.5570.24
222_Y528_I1.5420.24
57_V662_E1.5400.24
386_A460_D1.5380.24
468_A514_L1.5380.24
89_V462_I1.5360.24
68_S409_D1.5340.24
631_M641_N1.5320.24
451_E524_R1.5180.23
226_I230_A1.5130.23
54_W569_I1.5110.23
248_F268_Y1.5110.23
59_D404_L1.5040.23
78_F88_P1.4940.23
475_D506_W1.4930.23
264_K603_K1.4900.23
167_W240_K1.4800.22
550_E610_A1.4800.22
449_L650_L1.4790.22
54_W77_Q1.4710.22
557_Y594_I1.4690.22
613_W645_Y1.4670.22
280_N288_P1.4600.22
107_K226_I1.4600.22
542_L546_Q1.4550.22
315_R389_L1.4490.22
354_Q538_N1.4480.22
343_V350_T1.4430.22
320_D465_H1.4420.22
286_S512_R1.4420.22
317_M663_F1.4320.21
588_I633_L1.4280.21
511_S559_D1.4280.21
210_F215_R1.4260.21
432_Y465_H1.4210.21
88_P112_T1.4140.21
179_V457_A1.4120.21
248_F271_F1.4110.21
320_D645_Y1.4100.21
472_D552_W1.4080.21
609_Q645_Y1.4020.21
133_W233_M1.3990.21
439_D479_P1.3850.20
86_Y218_T1.3810.20
616_N652_N1.3800.20
108_A194_A1.3770.20
277_G284_L1.3770.20
403_V556_N1.3710.20
548_E551_A1.3620.20
139_P566_W1.3610.20
390_R460_D1.3580.20
403_V468_A1.3460.20
90_S138_A1.3460.20
171_R390_R1.3450.20
408_L446_V1.3420.20
478_A540_F1.3390.20
170_V659_I1.3360.20
383_S557_Y1.3340.20
150_K539_I1.3320.19
129_Q173_V1.3290.19
154_F569_I1.3270.19
223_R261_E1.3260.19
648_N651_H1.3240.19
291_L384_R1.3240.19
446_V484_Y1.3230.19
552_W570_M1.3140.19
324_V649_F1.3140.19
574_Y626_Q1.3100.19
204_Y481_I1.3040.19
377_M386_A1.3040.19
130_A279_A1.2990.19
254_E563_S1.2980.19
188_S204_Y1.2950.19
335_N466_D1.2890.19
230_A440_D1.2850.19
442_V639_V1.2830.19
447_G520_E1.2820.19
484_Y489_F1.2820.19
279_A288_P1.2790.18
201_L357_A1.2650.18
374_L449_L1.2610.18
483_A509_F1.2580.18
89_V228_L1.2540.18
536_A607_E1.2540.18
464_F521_L1.2530.18
480_A484_Y1.2500.18
268_Y454_A1.2500.18
165_A605_I1.2460.18
612_N615_K1.2450.18
262_E610_A1.2440.18
92_A247_V1.2380.18
58_E65_R1.2360.18
133_W154_F1.2360.18
404_L437_P1.2340.18
330_Q426_Q1.2330.18
234_T244_N1.2280.18
441_R444_A1.2260.18
490_S496_I1.2220.17
127_I389_L1.2210.17
333_D337_D1.2170.17
247_V272_F1.2150.17
247_V350_T1.2130.17
320_D613_W1.2100.17
335_N538_N1.2020.17
89_V171_R1.2000.17
82_R334_R1.1970.17
552_W613_W1.1880.17
67_M347_Q1.1820.17
481_I490_S1.1800.17
336_I343_V1.1790.17
112_T149_D1.1770.17
117_Y149_D1.1740.17
336_I440_D1.1730.17
301_F549_S1.1660.17
52_I214_A1.1650.16
160_D334_R1.1550.16
220_A603_K1.1510.16
318_H465_H1.1510.16
388_Q647_D1.1490.16
78_F127_I1.1460.16
139_P181_L1.1420.16
395_V436_S1.1400.16
541_A607_E1.1380.16
263_L439_D1.1350.16
141_G549_S1.1330.16
57_V74_L1.1330.16
186_W248_F1.1230.16
316_I386_A1.1220.16
313_P601_K1.1210.16
59_D164_F1.1200.16
318_H432_Y1.1200.16
201_L385_V1.1190.16
518_T643_G1.1120.16
125_F182_A1.1120.16
45_P77_Q1.1120.16
518_T586_W1.1100.16
315_R649_F1.1090.16
51_A368_V1.1090.16
93_Q108_A1.1010.15
247_V292_I1.0950.15
347_Q648_N1.0930.15
340_I556_N1.0930.15
125_F137_W1.0910.15
356_F490_S1.0900.15
129_Q368_V1.0900.15
291_L392_R1.0860.15
531_P567_T1.0850.15
277_G506_W1.0810.15
139_P236_Y1.0790.15
466_D645_Y1.0780.15
148_A261_E1.0740.15
207_R219_A1.0720.15
51_A112_T1.0670.15
481_I506_W1.0660.15
175_R641_N1.0660.15
214_A486_Q1.0650.15
219_A648_N1.0640.15
219_A455_G1.0640.15
519_L563_S1.0640.15
400_W645_Y1.0600.15
332_M438_F1.0590.15
57_V602_D1.0590.15
85_G206_N1.0580.15
137_W177_R1.0560.15
290_V368_V1.0550.15
69_V277_G1.0500.15
446_V482_T1.0480.15
538_N576_E1.0480.15
462_I533_I1.0450.15
327_E337_D1.0430.15
660_R665_T1.0420.15
552_W609_Q1.0410.15
319_I337_D1.0410.15
120_F271_F1.0410.15
478_A652_N1.0380.14
575_L609_Q1.0370.14
202_P205_V1.0360.14
94_I164_F1.0360.14
191_G202_P1.0310.14
93_Q295_N1.0290.14
472_D575_L1.0290.14
539_I548_E1.0270.14
373_R449_L1.0260.14
389_L560_F1.0220.14
604_S634_L1.0210.14
444_A449_L1.0190.14
408_L465_H1.0180.14
192_I396_N1.0160.14
574_Y583_A1.0150.14
320_D432_Y1.0110.14
171_R460_D1.0050.14
439_D540_F1.0050.14
199_S291_L1.0020.14
311_K377_M1.0020.14
484_Y497_R1.0000.14
106_E554_A0.9990.14
356_F524_R0.9960.14
226_I603_K0.9950.14
533_I631_M0.9870.14
152_V210_F0.9860.14
276_S469_L0.9860.14
343_V436_S0.9840.14
188_S365_V0.9840.14
211_T347_Q0.9830.14
165_A489_F0.9810.14
469_L605_I0.9790.14
78_F389_L0.9770.14
214_A546_Q0.9770.14
93_Q476_A0.9760.14
168_Q523_A0.9720.14
199_S336_I0.9720.14
110_V180_E0.9710.14
168_Q549_S0.9700.13
118_Q182_A0.9690.13
51_A337_D0.9670.13
49_F78_F0.9670.13
432_Y466_D0.9640.13
334_R596_N0.9620.13
80_W209_Y0.9620.13
631_M642_Y0.9610.13
66_F159_V0.9550.13
438_F513_A0.9550.13
512_R584_D0.9540.13
586_W664_S0.9510.13
450_Y647_D0.9510.13
469_L652_N0.9510.13
473_Y492_S0.9490.13
139_P556_N0.9450.13
431_Q471_S0.9440.13
73_A295_N0.9420.13
451_E554_A0.9400.13
220_A520_E0.9390.13
164_F664_S0.9390.13
269_D533_I0.9380.13
194_A259_A0.9360.13
522_S641_N0.9350.13
237_L406_W0.9340.13
242_E547_P0.9340.13
69_V531_P0.9320.13
549_S552_W0.9320.13
177_R209_Y0.9300.13
145_D185_T0.9290.13
330_Q546_Q0.9290.13
268_Y301_F0.9260.13
335_N613_W0.9240.13
561_L598_P0.9230.13
419_P583_A0.9220.13
470_L544_V0.9220.13
259_A605_I0.9180.13
205_V268_Y0.9180.13
194_A362_D0.9180.13
68_S298_L0.9170.13
156_D557_Y0.9170.13
465_H572_M0.9160.13
379_A648_N0.9140.13
139_P630_W0.9130.13
51_A642_Y0.9120.13
401_M460_D0.9120.13
165_A318_H0.9100.13
169_Q622_I0.9100.13
159_V182_A0.9070.13
86_Y89_V0.9060.13
239_T533_I0.9050.13
350_T587_L0.9050.13
544_V558_A0.9040.13
244_N485_Q0.8970.13
329_L443_R0.8970.13
244_N454_A0.8960.12
387_W514_L0.8920.12
405_S540_F0.8910.12
160_D459_F0.8880.12
342_R450_Y0.8870.12
49_F65_R0.8870.12
165_A272_F0.8840.12
465_H609_Q0.8840.12
170_V247_V0.8830.12
559_D643_G0.8830.12
78_F133_W0.8830.12
125_F183_S0.8780.12
48_G496_I0.8780.12
494_S623_S0.8770.12
357_A540_F0.8750.12
177_R657_D0.8750.12
607_E647_D0.8740.12
187_N352_Y0.8740.12
69_V296_P0.8730.12
583_A659_I0.8720.12
255_A278_L0.8710.12
594_I606_L0.8710.12
222_Y464_F0.8690.12
135_A361_G0.8690.12
480_A506_W0.8680.12
518_T521_L0.8680.12
237_L294_N0.8630.12
393_S427_I0.8630.12
454_A666_A0.8610.12
49_F284_L0.8590.12
81_L531_P0.8570.12
119_S349_S0.8560.12
243_V349_S0.8560.12
246_H351_V0.8540.12
141_G509_F0.8540.12
287_I349_S0.8530.12
556_N642_Y0.8500.12
320_D538_N0.8490.12
177_R349_S0.8480.12
218_T221_E0.8470.12
352_Y574_Y0.8450.12
381_I492_S0.8440.12
125_F375_L0.8420.12
294_N391_T0.8420.12
273_T345_D0.8410.12
487_A509_F0.8410.12
182_A438_F0.8390.12
340_I539_I0.8390.12
466_D613_W0.8370.12
284_L413_T0.8370.12
154_F273_T0.8350.12
185_T306_I0.8350.12
192_I584_D0.8330.12
295_N442_V0.8320.12
169_Q177_R0.8310.12
226_I540_F0.8310.12
136_V343_V0.8300.12
375_L499_N0.8300.12
149_D162_E0.8300.12
320_D609_Q0.8270.12
145_D218_T0.8270.12
400_W472_D0.8260.12
485_Q501_E0.8260.12
336_I438_F0.8240.12
318_H569_I0.8230.12
68_S106_E0.8200.12
453_L459_F0.8200.12
481_I546_Q0.8200.12
113_F242_E0.8190.12
539_I641_N0.8150.11
125_F385_V0.8140.11
253_G644_Y0.8140.11
241_V377_M0.8120.11
610_A629_H0.8110.11
136_V350_T0.8100.11
512_R516_D0.8100.11
496_I521_L0.8090.11
450_Y607_E0.8080.11
192_I261_E0.8070.11
574_Y578_V0.8060.11
493_L566_W0.8040.11
52_I149_D0.8030.11
138_A350_T0.8010.11
381_I411_T0.8010.11
88_P586_W0.8010.11
307_T639_V0.7970.11
413_T507_A0.7970.11
400_W552_W0.7970.11
128_L242_E0.7960.11
315_R664_S0.7960.11
462_I640_K0.7950.11
74_L586_W0.7940.11
354_Q613_W0.7930.11
283_Q288_P0.7930.11
391_T524_R0.7930.11
199_S206_N0.7910.11
320_D570_M0.7900.11
99_R622_I0.7880.11
85_G569_I0.7870.11
76_E318_H0.7870.11
201_L390_R0.7870.11
208_A348_I0.7870.11
220_A503_F0.7860.11
76_E148_A0.7860.11
159_V188_S0.7840.11
247_V471_S0.7840.11
56_N127_I0.7840.11
464_F518_T0.7840.11
258_I303_Q0.7840.11
103_P592_N0.7830.11
610_A631_M0.7830.11
61_A238_R0.7810.11
495_E499_N0.7810.11
164_F514_L0.7790.11
131_F632_S0.7790.11
443_R623_S0.7780.11
544_V569_I0.7780.11
85_G567_T0.7770.11
161_R556_N0.7760.11
258_I262_E0.7760.11
219_A604_S0.7760.11
89_V185_T0.7750.11
149_D265_K0.7740.11
75_R637_N0.7730.11
152_V155_G0.7730.11
74_L397_I0.7720.11
201_L603_K0.7720.11
48_G214_A0.7710.11
600_A604_S0.7690.11
160_D237_L0.7690.11
136_V188_S0.7670.11
101_G173_V0.7670.11
498_Q502_Q0.7660.11
201_L206_N0.7660.11
603_K650_L0.7660.11
120_F260_I0.7650.11
124_V563_S0.7650.11
320_D576_E0.7650.11
357_A623_S0.7640.11
147_P185_T0.7640.11
78_F186_W0.7620.11
185_T206_N0.7620.11
354_Q400_W0.7620.11
131_F389_L0.7600.11
364_L433_H0.7600.11
152_V408_L0.7570.11
414_R529_R0.7560.11
518_T560_F0.7560.11
295_N337_D0.7560.11
133_W586_W0.7550.11
112_T639_V0.7540.11
168_Q539_I0.7540.11
313_P346_M0.7530.11
238_R301_F0.7510.11
149_D334_R0.7500.11
78_F187_N0.7490.11
356_F451_E0.7490.11
139_P257_G0.7490.11
575_L613_W0.7490.11
118_Q622_I0.7480.11
498_Q546_Q0.7480.11
179_V346_M0.7470.11
315_R397_I0.7470.11
508_R642_Y0.7460.11
136_V247_V0.7450.11
52_I156_D0.7450.11
348_I377_M0.7440.11
476_A484_Y0.7440.11
168_Q615_K0.7420.11
446_V552_W0.7420.11
221_E577_G0.7410.11
76_E658_L0.7410.11
476_A481_I0.7410.11
401_M405_S0.7410.11
317_M332_M0.7370.11
168_Q447_G0.7360.11
185_T260_I0.7350.11
49_F305_I0.7340.10
296_P543_P0.7330.10
221_E346_M0.7330.10
54_W245_P0.7330.10
287_I603_K0.7320.10
321_L339_L0.7320.10
98_H346_M0.7300.10
377_M381_I0.7300.10
170_V346_M0.7280.10
594_I604_S0.7280.10
230_A643_G0.7280.10
233_M630_W0.7250.10
568_A607_E0.7250.10
430_E546_Q0.7240.10
215_R218_T0.7230.10
287_I300_E0.7230.10
337_D384_R0.7230.10
383_S605_I0.7220.10
346_M652_N0.7220.10
419_P529_R0.7220.10
78_F224_E0.7210.10
150_K386_A0.7210.10
333_D336_I0.7210.10
624_S653_Q0.7200.10
194_A377_M0.7200.10
70_R308_V0.7190.10
547_P606_L0.7180.10
113_F272_F0.7170.10
409_D600_A0.7170.10
172_E385_V0.7160.10
442_V529_R0.7160.10
88_P133_W0.7140.10
148_A386_A0.7130.10
103_P112_T0.7130.10
389_L664_S0.7120.10
174_A381_I0.7120.10
330_Q482_T0.7110.10
301_F542_L0.7100.10
160_D581_K0.7080.10
224_E567_T0.7080.10
540_F605_I0.7080.10
529_R543_P0.7060.10
144_V186_W0.7060.10
591_T601_K0.7050.10
543_P553_F0.7040.10
78_F128_L0.7030.10
58_E68_S0.7030.10
56_N389_L0.7020.10
92_A272_F0.7020.10
222_Y567_T0.7010.10
208_A652_N0.7010.10
207_R294_N0.6990.10
515_T518_T0.6990.10
72_S188_S0.6980.10
405_S442_V0.6970.10
68_S374_L0.6960.10
291_L339_L0.6960.10
345_D365_V0.6960.10
201_L374_L0.6950.10
361_G609_Q0.6950.10
320_D575_L0.6940.10
75_R106_E0.6940.10
158_L188_S0.6940.10
567_T602_D0.6910.10
476_A493_L0.6900.10
464_F663_F0.6900.10
538_N609_Q0.6900.10
593_Q651_H0.6890.10
272_F346_M0.6880.10
319_I503_F0.6880.10
403_V643_G0.6870.10
486_Q490_S0.6860.10
465_H576_E0.6860.10
74_L560_F0.6860.10
118_Q157_E0.6850.10
48_G204_Y0.6840.10
439_D477_S0.6840.10
71_T295_N0.6840.10
108_A470_L0.6840.10
127_I397_I0.6840.10
244_N652_N0.6830.10
145_D278_L0.6820.10
162_E254_E0.6810.10
489_F496_I0.6790.10
165_A206_N0.6780.10
318_H575_L0.6770.10
560_F626_Q0.6770.10
120_F415_V0.6760.10
163_Y194_A0.6760.10
152_V620_Q0.6750.10
526_K540_F0.6750.10
340_I381_I0.6750.10
122_T211_T0.6740.10
367_E504_K0.6730.10
499_N651_H0.6730.10
388_Q517_F0.6730.10
414_R419_P0.6710.10
57_V237_L0.6700.10
77_Q174_A0.6700.10
129_Q243_V0.6690.10
51_A203_V0.6680.10
56_N560_F0.6670.10
141_G350_T0.6670.10
439_D603_K0.6660.10
186_W247_V0.6650.10
150_K188_S0.6650.10
493_L597_I0.6650.10
569_I595_K0.6630.10
560_F586_W0.6630.10
63_D296_P0.6620.10
47_N492_S0.6610.10
256_N648_N0.6600.10
451_E456_H0.6600.10
515_T560_F0.6600.10
398_Y442_V0.6560.10
67_M292_I0.6550.10
301_F385_V0.6540.10
633_L639_V0.6540.10
165_A239_T0.6520.10
397_I612_N0.6520.10
478_A481_I0.6510.10
98_H462_I0.6460.10
389_L649_F0.6450.10
150_K327_E0.6450.10
244_N577_G0.6450.10
495_E562_K0.6440.10
404_L457_A0.6430.10
69_V438_F0.6420.09
638_G646_P0.6410.09
98_H520_E0.6400.09
357_A613_W0.6400.09
84_N170_V0.6400.09
268_Y366_K0.6390.09
233_M248_F0.6390.09
226_I605_I0.6380.09
465_H645_Y0.6370.09
572_M576_E0.6360.09
356_F385_V0.6350.09
56_N518_T0.6340.09
197_T440_D0.6340.09
108_A204_Y0.6300.09
396_N421_G0.6300.09
655_E666_A0.6290.09
168_Q293_A0.6280.09
194_A302_A0.6270.09
133_W630_W0.6270.09
159_V549_S0.6260.09
365_V623_S0.6260.09
191_G199_S0.6260.09
398_Y405_S0.6250.09
401_M533_I0.6250.09
647_D654_P0.6240.09
330_Q404_L0.6240.09
56_N315_R0.6240.09
89_V328_N0.6230.09
642_Y663_F0.6220.09
109_V505_Q0.6220.09
166_T237_L0.6200.09
404_L468_A0.6190.09
116_G372_N0.6180.09
111_L182_A0.6180.09
186_W350_T0.6180.09
438_F525_V0.6180.09
388_Q450_Y0.6150.09
426_Q554_A0.6150.09
372_N435_L0.6150.09
56_N71_T0.6140.09
352_Y529_R0.6130.09
649_F664_S0.6130.09
222_Y269_D0.6130.09
535_T571_A0.6120.09
205_V578_V0.6110.09
173_V540_F0.6110.09
159_V590_L0.6100.09
92_A177_R0.6090.09
384_R388_Q0.6090.09
526_K605_I0.6070.09
51_A96_E0.6070.09
52_I589_Q0.6070.09
431_Q469_L0.6070.09
348_I642_Y0.6060.09
298_L451_E0.6050.09
113_F128_L0.6040.09
173_V536_A0.6030.09
331_Q538_N0.6030.09
636_L642_Y0.6020.09
572_M607_E0.6020.09
44_W341_Q0.6010.09
592_N612_N0.6010.09
553_F630_W0.6010.09
235_E244_N0.6010.09
248_F341_Q0.6000.09
472_D576_E0.5990.09
446_V473_Y0.5980.09
238_R330_Q0.5980.09
150_K610_A0.5960.09
549_S667_W0.5950.09
272_F310_E0.5940.09
205_V248_F0.5940.09
496_I502_Q0.5940.09
44_W415_V0.5920.09
295_N665_T0.5910.09
131_F153_K0.5910.09
77_Q552_W0.5900.09
194_A262_E0.5900.09
371_P435_L0.5890.09
442_V588_I0.5890.09
90_S185_T0.5890.09
58_E64_Q0.5870.09
235_E653_Q0.5860.09
164_F649_F0.5850.09
264_K272_F0.5850.09
484_Y522_S0.5840.09
49_F449_L0.5840.09
80_W391_T0.5840.09
516_D616_N0.5820.09
127_I150_K0.5820.09
340_I344_K0.5810.09
352_Y549_S0.5810.09
152_V628_A0.5810.09
490_S498_Q0.5800.09
70_R610_A0.5790.09
254_E463_L0.5790.09
145_D643_G0.5790.09
156_D383_S0.5790.09
57_V583_A0.5790.09
100_G643_G0.5790.09
97_A155_G0.5790.09
317_M649_F0.5790.09
394_G540_F0.5790.09
48_G108_A0.5780.09
570_M645_Y0.5770.09
457_A525_V0.5760.09
465_H607_E0.5750.09
85_G544_V0.5750.09
612_N620_Q0.5750.09
146_T639_V0.5740.09
459_F464_F0.5740.09
261_E394_G0.5740.09
128_L315_R0.5740.09
257_G566_W0.5730.09
130_A635_Q0.5720.09
212_D523_A0.5710.09
77_Q569_I0.5710.09
117_Y275_E0.5700.09
259_A383_S0.5700.09
227_R265_K0.5700.09
122_T554_A0.5690.09
170_V593_Q0.5680.09
79_A440_D0.5670.09
518_T664_S0.5660.09
86_Y139_P0.5660.09
113_F131_F0.5650.09
249_V646_P0.5650.09
131_F181_L0.5650.09
205_V316_I0.5640.09
372_N572_M0.5630.09
327_E540_F0.5620.09
187_N298_L0.5600.09
466_D576_E0.5590.09
540_F613_W0.5590.09
208_A347_Q0.5590.09
578_V583_A0.5590.09
79_A347_Q0.5580.09
349_S648_N0.5570.09
465_H568_A0.5570.09
313_P356_F0.5550.09
323_Y388_Q0.5550.09
166_T224_E0.5550.09
65_R141_G0.5540.09
241_V346_M0.5540.09
156_D161_R0.5540.09
219_A442_V0.5500.09
144_V343_V0.5480.09
58_E77_Q0.5470.09
400_W575_L0.5460.09
400_W538_N0.5450.09
70_R268_Y0.5440.09
318_H613_W0.5440.09
352_Y528_I0.5440.09
135_A406_W0.5430.09
319_I339_L0.5420.09
554_A603_K0.5410.09
448_M513_A0.5410.09
167_W237_L0.5400.08
116_G400_W0.5380.08
400_W572_M0.5360.08
529_R635_Q0.5350.08
134_P464_F0.5350.08
386_A610_A0.5340.08
193_Q499_N0.5330.08
69_V78_F0.5330.08
238_R592_N0.5320.08
356_F585_Q0.5320.08
157_E218_T0.5320.08
231_V367_E0.5320.08
53_S179_V0.5320.08
94_I110_V0.5320.08
256_N425_A0.5310.08
249_V638_G0.5310.08
606_L643_G0.5300.08
320_D357_A0.5290.08
89_V101_G0.5290.08
137_W169_Q0.5290.08
212_D596_N0.5290.08
354_Q540_F0.5280.08
379_A454_A0.5270.08
190_Y298_L0.5260.08
238_R558_A0.5260.08
290_V484_Y0.5260.08
203_V449_L0.5260.08
504_K650_L0.5260.08
107_K471_S0.5260.08
139_P255_A0.5250.08
292_I338_V0.5250.08
475_D480_A0.5240.08
244_N398_Y0.5230.08
318_H609_Q0.5230.08
219_A378_K0.5230.08
201_L557_Y0.5210.08
389_L393_S0.5210.08
561_L634_L0.5200.08
291_L403_V0.5200.08
74_L257_G0.5200.08
417_Y440_D0.5190.08
323_Y575_L0.5190.08
54_W85_G0.5180.08
159_V169_Q0.5170.08
409_D419_P0.5170.08
201_L210_F0.5160.08
406_W514_L0.5160.08
109_V655_E0.5150.08
279_A506_W0.5140.08
260_I306_I0.5140.08
197_T207_R0.5140.08
177_R663_F0.5140.08
166_T292_I0.5130.08
296_P305_I0.5130.08
605_I608_L0.5130.08
193_Q211_T0.5120.08
245_P557_Y0.5120.08
163_Y661_P0.5110.08
362_D656_I0.5110.08
288_P532_H0.5100.08
385_V625_Q0.5100.08
375_L606_L0.5100.08
59_D547_P0.5080.08
292_I603_K0.5080.08
158_L544_V0.5080.08
318_H576_E0.5080.08
49_F422_E0.5070.08
441_R655_E0.5070.08
117_Y121_Y0.5070.08
52_I64_Q0.5050.08
482_T491_G0.5050.08
166_T482_T0.5040.08
292_I583_A0.5040.08
471_S513_A0.5040.08
155_G221_E0.5040.08
169_Q384_R0.5040.08
337_D496_I0.5030.08
54_W243_V0.5030.08
60_E652_N0.5020.08
123_R630_W0.5010.08
608_L627_L0.5010.08
145_D529_R0.5000.08
223_R524_R0.5000.08
237_L604_S0.5000.08
248_F659_I0.5000.08
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4f9dA 1 0.881 100 0.58 Contact Map
4p7oA 1 0.5149 100 0.753 Contact Map
3vusA 1 0.3914 100 0.796 Contact Map
5bu6A 2 0.3824 100 0.798 Contact Map
4u10A 1 0.3824 100 0.806 Contact Map
4wcjA 1 0.3467 100 0.843 Contact Map
4v33A 1 0.378 100 0.854 Contact Map
4l1gA 1 0.314 100 0.867 Contact Map
2w3zA 1 0.3348 100 0.904 Contact Map
2c1iA 1 0.3929 100 0.911 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0163 seconds.