GREMLIN Database
YCCS - Inner membrane protein YccS
UniProt: P75870 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13721
Length: 717 (628)
Sequences: 2264 (1795)
Seq/√Len: 71.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
254_S257_Q4.8661.00
639_L643_V4.2721.00
215_N218_K4.1831.00
404_G423_S3.8561.00
96_T398_S3.7121.00
288_L292_I3.6651.00
182_E286_Q3.5551.00
24_A153_L3.3581.00
400_V522_I3.2961.00
93_I97_L3.2061.00
247_I255_H3.1621.00
245_Q249_E3.1401.00
400_V423_S3.1381.00
467_V471_I3.0071.00
211_M215_N2.9351.00
535_Q591_N2.9101.00
248_H254_S2.9031.00
400_V526_A2.8151.00
137_Y140_P2.7981.00
311_I315_L2.7771.00
334_L342_D2.7551.00
96_T402_C2.7341.00
174_Y177_L2.6591.00
289_S292_I2.6511.00
141_M145_A2.5011.00
100_S391_F2.5001.00
248_H255_H2.4951.00
419_I518_I2.4711.00
152_V156_I2.3951.00
422_T516_T2.3751.00
418_W445_T2.3481.00
207_N218_K2.3081.00
204_A207_N2.3011.00
109_G112_Y2.2821.00
100_S398_S2.2761.00
316_E319_R2.2611.00
657_E660_V2.2561.00
407_I522_I2.2561.00
314_A319_R2.2531.00
418_W519_G2.2061.00
252_S257_Q2.1831.00
230_G233_G2.1361.00
210_L218_K2.1361.00
244_A252_S2.0911.00
575_R579_H2.0871.00
28_T149_W2.0781.00
330_T333_F2.0671.00
419_I515_D2.0571.00
363_N366_A2.0481.00
364_E368_D2.0291.00
519_G523_A2.0261.00
248_H253_S2.0231.00
550_N613_N2.0161.00
246_D250_R2.0091.00
249_E254_S1.9921.00
404_G522_I1.9571.00
327_L338_L1.9541.00
244_A256_I1.9531.00
248_H257_Q1.9511.00
241_Y255_H1.9441.00
329_K337_N1.9401.00
335_L342_D1.9351.00
472_T493_L1.9291.00
95_L123_A1.9171.00
639_L642_A1.9001.00
309_T313_A1.8981.00
95_L103_I1.8841.00
636_L639_L1.8791.00
286_Q289_S1.8711.00
249_E258_Y1.8591.00
269_D273_R1.8561.00
446_L450_A1.8531.00
250_R257_Q1.8501.00
368_D372_G1.8381.00
328_L335_L1.8221.00
333_F344_Q1.8181.00
645_Y654_P1.7961.00
178_A282_G1.7921.00
407_I518_I1.7691.00
252_S255_H1.7601.00
237_T244_A1.7581.00
447_V489_M1.7581.00
643_V653_Q1.7461.00
92_A402_C1.7421.00
437_R484_Y1.7301.00
495_V499_F1.7271.00
329_K333_F1.7231.00
642_A649_A1.7101.00
216_Q219_L1.7021.00
260_T263_E1.7001.00
245_Q250_R1.6951.00
28_T41_T1.6881.00
469_L497_L1.6761.00
551_C640_D1.6701.00
318_M326_D1.6681.00
444_G512_R1.6611.00
362_E366_A1.6541.00
463_E466_L1.6521.00
337_N342_D1.6430.99
415_H418_W1.6380.99
251_A255_H1.6310.99
270_V273_R1.6310.99
365_L370_P1.6260.99
261_L264_H1.6240.99
364_E367_D1.6220.99
257_Q260_T1.5930.99
643_V646_V1.5820.99
67_L151_N1.5800.99
178_A517_L1.5760.99
100_S104_L1.5680.99
586_A614_H1.5570.99
48_M146_G1.5540.99
99_T401_L1.5510.99
329_K332_G1.5420.99
242_F245_Q1.5250.99
405_Y420_L1.5000.99
318_M322_G1.4970.99
393_H429_P1.4960.99
640_D643_V1.4920.99
58_D62_G1.4920.99
232_R235_R1.4910.99
250_R253_S1.4810.99
317_R321_N1.4750.99
250_R254_S1.4690.99
94_G98_S1.4690.99
641_D645_Y1.4630.99
206_A211_M1.4540.99
175_E289_S1.4520.99
466_L470_V1.4510.99
241_Y244_A1.4450.99
176_Q179_R1.4410.99
458_F464_G1.4410.99
44_L47_G1.4390.99
431_Y596_P1.4390.99
289_S293_L1.4380.99
248_H252_S1.4330.99
401_L424_L1.4220.99
335_L341_I1.4210.99
406_A410_I1.4210.99
245_Q248_H1.4150.98
175_E290_R1.4110.98
315_L319_R1.4110.98
638_F650_L1.4060.98
646_V649_A1.4050.98
209_L213_T1.4020.98
487_A491_I1.3990.98
223_T227_G1.3980.98
556_A559_E1.3970.98
367_D373_L1.3970.98
636_L643_V1.3910.98
279_S283_Q1.3810.98
241_Y245_Q1.3790.98
419_I422_T1.3780.98
246_D251_A1.3780.98
218_K222_L1.3760.98
446_L513_V1.3740.98
327_L335_L1.3680.98
152_V155_L1.3610.98
477_F490_F1.3610.98
244_A254_S1.3600.98
337_N341_I1.3590.98
103_I397_M1.3580.98
319_R323_A1.3560.98
383_H388_S1.3510.98
241_Y247_I1.3500.98
464_G467_V1.3460.98
642_A645_Y1.3450.98
211_M218_K1.3450.98
394_A398_S1.3440.98
18_Y474_V1.3430.98
302_P316_E1.3370.98
557_I561_Y1.3350.98
337_N348_I1.3310.98
445_T516_T1.3280.98
89_W93_I1.3260.98
548_E651_H1.3240.98
334_L338_L1.3200.98
642_A650_L1.3160.98
244_A247_I1.3130.97
83_L87_W1.3120.97
318_M321_N1.3110.97
660_V663_A1.3100.97
301_D304_F1.3080.97
246_D254_S1.3070.97
518_I521_A1.2980.97
461_S464_G1.2960.97
492_T499_F1.2890.97
214_L217_T1.2890.97
253_S257_Q1.2880.97
212_A218_K1.2870.97
247_I254_S1.2850.97
643_V647_D1.2800.97
22_F26_C1.2790.97
175_E293_L1.2750.97
319_R322_G1.2740.97
378_L381_S1.2620.97
644_C653_Q1.2540.97
261_L265_F1.2540.97
333_F338_L1.2510.97
182_E282_G1.2490.97
291_C296_Q1.2480.97
249_E253_S1.2470.97
207_N211_M1.2470.97
333_F342_D1.2440.97
234_T238_L1.2440.97
643_V650_L1.2410.96
334_L341_I1.2400.96
210_L215_N1.2390.96
93_I361_D1.2340.96
243_V254_S1.2340.96
549_A581_R1.2320.96
327_L333_F1.2300.96
249_E257_Q1.2300.96
311_I314_A1.2260.96
251_A258_Y1.2240.96
338_L348_I1.2210.96
28_T32_P1.2210.96
329_K334_L1.2170.96
313_A317_R1.2160.96
489_M492_T1.2120.96
243_V257_Q1.2120.96
341_I344_Q1.2110.96
512_R519_G1.2100.96
370_P402_C1.2080.96
246_D249_E1.2000.96
235_R238_L1.2000.96
226_R230_G1.1990.96
259_Q262_R1.1960.96
648_D652_H1.1960.96
210_L219_L1.1960.96
652_H660_V1.1960.96
327_L330_T1.1930.96
175_E517_L1.1930.96
339_R342_D1.1920.96
534_W596_P1.1910.96
70_T115_I1.1890.95
342_D345_L1.1860.95
635_I648_D1.1820.95
559_E638_F1.1790.95
245_Q254_S1.1760.95
364_E450_A1.1740.95
506_F510_L1.1730.95
258_Y262_R1.1730.95
241_Y248_H1.1710.95
320_D323_A1.1690.95
84_L92_A1.1680.95
92_A95_L1.1670.95
233_G237_T1.1650.95
333_F337_N1.1600.95
83_L136_W1.1590.95
322_G326_D1.1570.95
60_L158_H1.1500.95
46_L49_V1.1500.95
602_I606_A1.1490.95
212_A215_N1.1470.95
499_F508_V1.1470.95
438_L524_W1.1440.94
451_I489_M1.1410.94
18_Y22_F1.1400.94
312_D316_E1.1390.94
22_F470_V1.1330.94
646_V650_L1.1320.94
418_W492_T1.1290.94
580_N584_E1.1280.94
328_L331_L1.1270.94
635_I642_A1.1270.94
335_L347_T1.1170.94
228_D231_Q1.1150.94
327_L332_G1.1150.94
243_V253_S1.1130.94
336_N342_D1.1080.93
75_F144_L1.1060.93
211_M219_L1.1050.93
281_Q285_C1.1020.93
449_I509_A1.0980.93
241_Y254_S1.0980.93
480_R487_A1.0970.93
132_L442_I1.0950.93
445_T492_T1.0900.93
644_C655_A1.0900.93
649_A654_P1.0900.93
241_Y250_R1.0830.93
479_F486_H1.0810.93
488_T491_I1.0810.93
179_R183_L1.0780.92
317_R320_D1.0760.92
277_L281_Q1.0730.92
315_L318_M1.0720.92
517_L521_A1.0710.92
644_C647_D1.0690.92
178_A289_S1.0680.92
334_L340_A1.0670.92
334_L337_N1.0640.92
392_R531_W1.0620.92
640_D644_C1.0590.92
223_T226_R1.0590.92
380_L610_L1.0580.92
217_T221_L1.0560.92
299_Q303_H1.0560.92
644_C648_D1.0520.92
344_Q347_T1.0500.91
303_H323_A1.0500.91
71_L147_A1.0490.91
398_S402_C1.0480.91
207_N214_L1.0470.91
314_A318_M1.0450.91
136_W140_P1.0410.91
642_A653_Q1.0410.91
211_M217_T1.0400.91
643_V655_A1.0390.91
641_D646_V1.0360.91
244_A250_R1.0340.91
288_L291_C1.0330.91
211_M214_L1.0310.91
384_F388_S1.0310.91
242_F246_D1.0300.91
179_R286_Q1.0300.91
426_V484_Y1.0290.91
284_A287_Q1.0290.91
330_T335_L1.0260.90
240_Y255_H1.0240.90
396_R520_C1.0240.90
294_L297_P1.0180.90
396_R418_W1.0160.90
328_L337_N1.0150.90
241_Y252_S1.0140.90
637_A656_D1.0060.90
261_L271_L1.0030.89
365_L369_S1.0030.89
318_M324_P1.0020.89
242_F249_E1.0010.89
328_L332_G0.9990.89
231_Q239_H0.9980.89
190_P341_I0.9980.89
419_I522_I0.9970.89
159_L162_P0.9970.89
362_E367_D0.9950.89
23_I320_D0.9940.89
231_Q235_R0.9940.89
209_L215_N0.9920.89
644_C651_H0.9910.89
429_P553_Y0.9910.89
252_S258_Y0.9900.89
262_R265_F0.9880.89
241_Y258_Y0.9860.89
621_S624_G0.9830.88
385_T394_A0.9800.88
637_A640_D0.9790.88
429_P535_Q0.9790.88
366_A373_L0.9780.88
254_S260_T0.9770.88
23_I223_T0.9730.88
426_V519_G0.9730.88
260_T264_H0.9730.88
310_H313_A0.9730.88
657_E662_E0.9680.88
214_L218_K0.9660.88
342_D348_I0.9640.88
208_G219_L0.9640.88
286_Q292_I0.9620.87
327_L342_D0.9620.87
244_A255_H0.9610.87
17_Y20_R0.9590.87
80_S93_I0.9590.87
305_E308_F0.9540.87
94_G99_T0.9540.87
250_R256_I0.9520.87
331_L344_Q0.9500.87
253_S256_I0.9460.87
334_L345_L0.9460.87
407_I637_A0.9440.86
331_L339_R0.9440.86
210_L213_T0.9430.86
336_N347_T0.9410.86
443_I655_A0.9410.86
638_F648_D0.9410.86
549_A574_A0.9400.86
396_R579_H0.9390.86
618_S621_S0.9380.86
76_I412_G0.9380.86
330_T340_A0.9360.86
332_G337_N0.9340.86
253_S261_L0.9330.86
510_L514_I0.9320.86
26_C470_V0.9310.86
178_A399_L0.9280.85
638_F642_A0.9270.85
26_C467_V0.9260.85
636_L644_C0.9250.85
363_N367_D0.9240.85
207_N215_N0.9220.85
525_A590_S0.9210.85
106_G113_A0.9210.85
302_P307_A0.9200.85
340_A346_A0.9200.85
657_E661_N0.9180.85
91_F127_M0.9170.85
417_Y515_D0.9120.84
269_D272_F0.9100.84
113_A452_G0.9080.84
610_L614_H0.9060.84
146_G150_Y0.9050.84
240_Y244_A0.9040.84
240_Y247_I0.9040.84
35_L38_V0.9030.84
329_K336_N0.9020.84
400_V438_L0.9020.84
349_E364_E0.8970.83
138_Q141_M0.8960.83
327_L331_L0.8950.83
518_I584_E0.8950.83
207_N222_L0.8950.83
484_Y519_G0.8920.83
643_V649_A0.8860.83
208_G211_M0.8850.83
454_P521_A0.8850.83
259_Q265_F0.8840.83
342_D347_T0.8800.82
285_C454_P0.8790.82
404_G419_I0.8750.82
418_W516_T0.8740.82
207_N210_L0.8700.82
337_N344_Q0.8690.81
367_D370_P0.8690.81
244_A251_A0.8680.81
574_A577_D0.8670.81
608_R613_N0.8650.81
40_L44_L0.8650.81
394_A408_I0.8610.81
614_H617_T0.8600.81
640_D648_D0.8590.81
332_G341_I0.8570.81
454_P518_I0.8570.81
431_Y534_W0.8560.80
89_W394_A0.8550.80
153_L156_I0.8550.80
635_I638_F0.8550.80
210_L221_L0.8540.80
57_D499_F0.8530.80
649_A656_D0.8510.80
130_T139_Q0.8500.80
46_L50_A0.8500.80
643_V652_H0.8500.80
249_E252_S0.8500.80
636_L642_A0.8490.80
306_R521_A0.8490.80
278_M282_G0.8460.80
290_R331_L0.8460.80
441_R484_Y0.8450.80
240_Y243_V0.8430.79
446_L517_L0.8420.79
511_P515_D0.8420.79
336_N345_L0.8410.79
19_A263_E0.8370.79
24_A28_T0.8370.79
98_S123_A0.8330.79
303_H308_F0.8310.78
20_R31_F0.8310.78
431_Y516_T0.8300.78
640_D654_P0.8280.78
20_R159_L0.8270.78
643_V648_D0.8230.78
316_E323_A0.8200.78
299_Q314_A0.8200.78
647_D652_H0.8200.78
82_E139_Q0.8200.78
565_R570_A0.8190.77
211_M216_Q0.8180.77
422_T431_Y0.8180.77
502_L505_G0.8170.77
548_E647_D0.8170.77
241_Y253_S0.8150.77
214_L222_L0.8150.77
276_R280_M0.8150.77
243_V248_H0.8150.77
377_W381_S0.8140.77
635_I645_Y0.8110.77
49_V452_G0.8110.77
552_R559_E0.8100.77
134_E137_Y0.8100.77
592_M612_L0.8090.77
210_L214_L0.8080.77
12_N15_W0.8080.77
167_Q178_A0.8060.76
90_L94_G0.8040.76
639_L653_Q0.8010.76
246_D261_L0.8010.76
106_G432_N0.7990.76
266_R443_I0.7980.76
301_D308_F0.7970.76
111_R114_T0.7960.75
483_Q489_M0.7960.75
416_G420_L0.7950.75
339_R343_A0.7940.75
637_A655_A0.7940.75
436_H440_L0.7890.75
245_Q253_S0.7880.75
52_A57_D0.7870.75
328_L333_F0.7860.75
649_A655_A0.7840.74
246_D257_Q0.7830.74
418_W512_R0.7830.74
427_C445_T0.7820.74
343_A346_A0.7820.74
638_F643_V0.7810.74
430_N477_F0.7810.74
244_A265_F0.7790.74
84_L90_L0.7770.74
614_H624_G0.7770.74
327_L337_N0.7750.73
428_Q437_R0.7740.73
609_L616_F0.7730.73
225_L229_R0.7720.73
438_L591_N0.7700.73
336_N341_I0.7700.73
330_T334_L0.7700.73
283_Q287_Q0.7700.73
144_L468_L0.7690.73
534_W592_M0.7690.73
570_A587_S0.7690.73
23_I525_A0.7680.73
103_I107_G0.7660.73
547_T647_D0.7660.73
93_I296_Q0.7650.72
284_A291_C0.7650.72
635_I639_L0.7650.72
650_L657_E0.7650.72
327_L341_I0.7640.72
257_Q261_L0.7630.72
47_G396_R0.7600.72
99_T103_I0.7600.72
46_L453_I0.7600.72
153_L468_L0.7590.72
305_E450_A0.7590.72
327_L348_I0.7540.71
54_T67_L0.7540.71
477_F480_R0.7530.71
135_H139_Q0.7520.71
452_G496_L0.7520.71
464_G468_L0.7520.71
173_C177_L0.7510.71
193_E232_R0.7510.71
252_S256_I0.7490.71
627_R630_L0.7480.71
117_F121_L0.7450.70
278_M304_F0.7440.70
278_M292_I0.7430.70
102_F106_G0.7430.70
452_G519_G0.7420.70
484_Y488_T0.7420.70
455_V459_V0.7400.70
300_H306_R0.7390.70
454_P458_F0.7370.70
642_A651_H0.7340.69
331_L337_N0.7340.69
259_Q263_E0.7290.69
516_T534_W0.7290.69
236_R239_H0.7290.69
147_A245_Q0.7290.69
302_P306_R0.7280.69
97_L101_G0.7270.69
395_V471_I0.7270.69
638_F649_A0.7270.69
430_N433_A0.7260.69
637_A643_V0.7250.68
333_F340_A0.7240.68
130_T134_E0.7240.68
20_R97_L0.7220.68
330_T344_Q0.7190.68
630_L633_P0.7190.68
393_H523_A0.7180.68
291_C295_R0.7170.68
636_L640_D0.7170.68
55_D58_D0.7160.67
152_V462_L0.7160.67
244_A257_Q0.7150.67
210_L216_Q0.7150.67
473_G476_F0.7150.67
142_Y496_L0.7140.67
335_L339_R0.7130.67
80_S94_G0.7120.67
246_D255_H0.7120.67
636_L649_A0.7120.67
141_M633_P0.7110.67
329_K345_L0.7100.67
337_N340_A0.7100.67
83_L86_P0.7100.67
102_F119_A0.7100.67
18_Y26_C0.7090.67
639_L651_H0.7090.67
292_I296_Q0.7070.66
278_M288_L0.7050.66
641_D649_A0.7040.66
619_Y624_G0.7040.66
245_Q257_Q0.7040.66
100_S111_R0.7030.66
156_I217_T0.7030.66
361_D366_A0.7030.66
243_V250_R0.7020.66
439_K443_I0.7020.66
657_E663_A0.7020.66
239_H250_R0.7010.66
375_D378_L0.7010.66
555_D640_D0.7000.66
210_L253_S0.6990.66
472_T513_V0.6970.65
393_H432_N0.6960.65
84_L94_G0.6960.65
456_L515_D0.6940.65
181_L281_Q0.6930.65
254_S258_Y0.6920.65
651_H654_P0.6910.65
179_R186_R0.6900.65
278_M293_L0.6890.64
215_N222_L0.6890.64
75_F140_P0.6870.64
499_F516_T0.6870.64
374_S395_V0.6870.64
180_Y184_K0.6870.64
207_N217_T0.6860.64
47_G81_V0.6860.64
93_I101_G0.6860.64
645_Y649_A0.6860.64
234_T239_H0.6860.64
648_D651_H0.6850.64
615_T619_Y0.6850.64
525_A558_L0.6840.64
485_A490_F0.6840.64
330_T336_N0.6830.64
139_Q142_Y0.6810.64
247_I252_S0.6810.64
136_W458_F0.6800.63
95_L99_T0.6790.63
112_Y425_F0.6780.63
292_I295_R0.6780.63
107_G112_Y0.6760.63
423_S526_A0.6750.63
240_Y246_D0.6750.63
393_H516_T0.6730.63
105_L608_R0.6730.63
36_G39_K0.6730.63
313_A320_D0.6720.63
340_A344_Q0.6710.62
64_L239_H0.6710.62
120_L124_I0.6700.62
116_A392_R0.6700.62
472_T490_F0.6700.62
313_A316_E0.6700.62
608_R612_L0.6690.62
385_T517_L0.6670.62
603_R607_F0.6670.62
96_T237_T0.6650.62
384_F403_F0.6640.62
641_D644_C0.6640.62
613_N617_T0.6620.61
375_D379_R0.6600.61
246_D253_S0.6600.61
285_C290_R0.6580.61
72_F76_I0.6580.61
54_T57_D0.6580.61
636_L641_D0.6570.61
571_Y575_R0.6560.61
100_S103_I0.6560.61
105_L412_G0.6560.61
259_Q264_H0.6550.61
260_T265_F0.6540.60
304_F307_A0.6540.60
576_R579_H0.6530.60
124_I127_M0.6520.60
470_V474_V0.6510.60
19_A469_L0.6500.60
280_M311_I0.6500.60
380_L586_A0.6500.60
337_N346_A0.6490.60
258_Y261_L0.6480.60
651_H655_A0.6480.60
241_Y256_I0.6480.60
393_H425_F0.6470.60
407_I468_L0.6460.60
245_Q256_I0.6450.59
101_G104_L0.6450.59
642_A648_D0.6420.59
366_A371_H0.6410.59
328_L340_A0.6410.59
400_V531_W0.6400.59
626_H631_T0.6400.59
366_A369_S0.6400.59
312_D334_L0.6390.59
488_T515_D0.6370.58
18_Y616_F0.6350.58
653_Q657_E0.6340.58
243_V249_E0.6340.58
637_A642_A0.6330.58
396_R530_I0.6330.58
30_A263_E0.6330.58
101_G529_Y0.6320.58
187_M454_P0.6320.58
209_L216_Q0.6310.58
413_M456_L0.6290.57
247_I257_Q0.6280.57
141_M652_H0.6280.57
636_L650_L0.6280.57
309_T323_A0.6280.57
221_L224_R0.6260.57
306_R349_E0.6260.57
37_D40_L0.6260.57
103_I110_Q0.6260.57
520_C621_S0.6260.57
143_L423_S0.6260.57
240_Y250_R0.6250.57
141_M289_S0.6250.57
21_I52_A0.6240.57
440_L483_Q0.6240.57
422_T426_V0.6240.57
442_I520_C0.6240.57
306_R309_T0.6230.57
329_K335_L0.6230.57
332_G336_N0.6220.57
367_D372_G0.6220.57
396_R416_G0.6220.57
146_G575_R0.6210.57
118_G452_G0.6210.57
276_R306_R0.6200.56
315_L569_L0.6200.56
99_T104_L0.6190.56
504_E617_T0.6180.56
506_F509_A0.6180.56
206_A443_I0.6170.56
27_G149_W0.6160.56
170_L522_I0.6150.56
189_D214_L0.6150.56
497_L556_A0.6140.56
547_T654_P0.6140.56
46_L506_F0.6130.56
636_L648_D0.6120.55
245_Q255_H0.6110.55
311_I318_M0.6110.55
368_D373_L0.6110.55
228_D233_G0.6110.55
333_F336_N0.6110.55
549_A553_Y0.6100.55
334_L339_R0.6090.55
641_D660_V0.6080.55
397_M553_Y0.6080.55
54_T118_G0.6060.55
152_V641_D0.6040.54
407_I462_L0.6040.54
63_R426_V0.6020.54
305_E447_V0.6010.54
408_I515_D0.6000.54
589_V597_N0.5990.54
272_F275_Q0.5980.54
387_E395_V0.5970.54
278_M294_L0.5950.53
23_I399_L0.5950.53
229_R235_R0.5950.53
392_R424_L0.5940.53
645_Y652_H0.5940.53
21_I56_L0.5930.53
380_L648_D0.5930.53
361_D395_V0.5920.53
323_A326_D0.5920.53
236_R241_Y0.5910.53
641_D654_P0.5910.53
149_W153_L0.5910.53
329_K338_L0.5910.53
468_L497_L0.5890.53
246_D252_S0.5890.53
422_T441_R0.5890.53
67_L377_W0.5890.53
632_N640_D0.5880.53
183_L205_L0.5880.53
62_G547_T0.5880.53
89_W92_A0.5880.53
620_I642_A0.5850.52
638_F651_H0.5850.52
131_S140_P0.5850.52
271_L279_S0.5840.52
63_R396_R0.5840.52
220_S227_G0.5840.52
237_T240_Y0.5830.52
638_F645_Y0.5830.52
76_I80_S0.5830.52
488_T516_T0.5820.52
113_A397_M0.5820.52
45_T49_V0.5820.52
210_L217_T0.5810.52
283_Q301_D0.5790.51
61_A65_R0.5790.51
422_T575_R0.5790.51
603_R609_L0.5780.51
243_V252_S0.5770.51
95_L109_G0.5770.51
286_Q290_R0.5750.51
152_V235_R0.5750.51
249_E255_H0.5750.51
242_F252_S0.5740.51
184_K539_L0.5720.51
589_V596_P0.5720.51
441_R492_T0.5720.51
653_Q660_V0.5720.51
114_T496_L0.5710.50
445_T512_R0.5710.50
280_M286_Q0.5700.50
136_W142_Y0.5700.50
283_Q302_P0.5690.50
238_L253_S0.5670.50
314_A322_G0.5660.50
338_L341_I0.5660.50
273_R314_A0.5660.50
242_F255_H0.5650.50
399_L564_G0.5650.50
215_N219_L0.5650.50
346_A556_A0.5640.50
635_I656_D0.5620.49
306_R467_V0.5610.49
638_F653_Q0.5600.49
277_L293_L0.5590.49
190_P194_D0.5580.49
345_L368_D0.5580.49
74_F120_L0.5570.49
307_A317_R0.5570.49
410_I457_W0.5570.49
206_A215_N0.5550.48
336_N349_E0.5550.48
372_G380_L0.5530.48
20_R153_L0.5530.48
66_N106_G0.5530.48
97_L317_R0.5520.48
121_L136_W0.5520.48
283_Q309_T0.5520.48
364_E370_P0.5510.48
143_L146_G0.5510.48
96_T99_T0.5510.48
209_L471_I0.5510.48
549_A552_R0.5510.48
28_T48_M0.5500.48
317_R322_G0.5500.48
381_S385_T0.5500.48
379_R468_L0.5500.48
45_T498_C0.5490.48
329_K344_Q0.5490.48
124_I142_Y0.5480.48
535_Q592_M0.5480.48
641_D647_D0.5480.48
377_W380_L0.5470.47
459_V462_L0.5460.47
550_N582_D0.5460.47
98_S288_L0.5440.47
24_A56_L0.5440.47
76_I309_T0.5430.47
645_Y650_L0.5420.47
70_T455_V0.5420.47
30_A72_F0.5420.47
172_R216_Q0.5410.47
60_L156_I0.5400.47
150_Y405_Y0.5400.47
602_I609_L0.5400.47
207_N220_S0.5390.47
257_Q264_H0.5380.46
220_S224_R0.5380.46
495_V516_T0.5380.46
20_R154_T0.5380.46
237_T254_S0.5380.46
212_A222_L0.5370.46
76_I650_L0.5370.46
571_Y579_H0.5370.46
152_V545_R0.5360.46
77_A454_P0.5360.46
34_W37_D0.5350.46
421_L519_G0.5350.46
282_G285_C0.5350.46
546_A578_A0.5350.46
366_A450_A0.5340.46
221_L554_L0.5340.46
275_Q286_Q0.5340.46
434_T452_G0.5340.46
395_V399_L0.5330.46
105_L156_I0.5330.46
113_A120_L0.5320.46
646_V653_Q0.5310.46
652_H655_A0.5310.46
251_A536_F0.5310.46
335_L340_A0.5310.46
204_A216_Q0.5300.45
39_K446_L0.5290.45
492_T500_N0.5280.45
152_V646_V0.5280.45
76_I149_W0.5270.45
107_G396_R0.5270.45
238_L241_Y0.5270.45
182_E186_R0.5270.45
395_V450_A0.5260.45
50_A288_L0.5250.45
120_L128_L0.5250.45
280_M292_I0.5250.45
101_G153_L0.5240.45
415_H499_F0.5240.45
614_H619_Y0.5240.45
314_A321_N0.5230.45
570_A574_A0.5230.45
227_G230_G0.5210.44
449_I492_T0.5210.44
139_Q180_Y0.5200.44
317_R323_A0.5200.44
438_L492_T0.5200.44
215_N220_S0.5200.44
134_E138_Q0.5200.44
538_N542_M0.5190.44
182_E279_S0.5190.44
575_R621_S0.5190.44
258_Y265_F0.5180.44
82_E140_P0.5170.44
104_L396_R0.5170.44
514_I651_H0.5160.44
302_P348_I0.5160.44
492_T512_R0.5160.44
46_L122_I0.5150.44
428_Q530_I0.5140.43
640_D649_A0.5130.43
210_L220_S0.5130.43
31_F122_I0.5130.43
336_N340_A0.5130.43
270_V274_F0.5100.43
426_V449_I0.5100.43
632_N662_E0.5090.43
23_I544_E0.5090.43
181_L334_L0.5080.43
393_H534_W0.5080.43
244_A564_G0.5070.43
91_F98_S0.5070.43
296_Q309_T0.5050.42
33_W77_A0.5050.42
452_G532_P0.5050.42
468_L495_V0.5050.42
275_Q278_M0.5050.42
513_V635_I0.5030.42
653_Q656_D0.5030.42
640_D645_Y0.5020.42
417_Y516_T0.5010.42
421_L596_P0.5000.42
155_L539_L0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4q4gX 1 0 36.3 0.97 Contact Map
2oltA 5 0.2622 29.9 0.971 Contact Map
4cgkA 3 0.2329 24.9 0.973 Contact Map
4ltoA 3 0.1743 19 0.974 Contact Map
4cbcA 3 0.1144 14.6 0.975 Contact Map
2f95B 2 0.0711 12.2 0.976 Contact Map
4eneA 2 0.2371 11 0.977 Contact Map
3l39A 3 0.2622 10.1 0.977 Contact Map
4yayA 1 0.1367 9.5 0.977 Contact Map
2l7nA 1 0.1925 8.8 0.978 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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