GREMLIN Database
RLMKL - Ribosomal RNA large subunit methyltransferase K/L
UniProt: P75864 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13717
Length: 702 (694)
Sequences: 489 (308)
Seq/√Len: 11.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
213_D246_R6.7491.00
595_Q624_R6.3631.00
430_V462_I6.3511.00
275_A286_F5.6841.00
547_S566_T5.5481.00
6_A37_F5.0391.00
508_A558_L4.7711.00
6_A57_I4.6071.00
275_A280_I4.2241.00
541_D647_R4.1210.99
82_T119_A4.0790.99
5_F34_G3.9800.99
181_I307_L3.9220.99
141_V148_A3.7230.99
529_A653_M3.7000.99
46_Q242_E3.5470.98
542_F564_T3.5430.98
550_G566_T3.2930.97
503_V522_L3.2900.97
246_R250_G3.2220.97
439_V470_L3.1750.97
559_G611_L3.1680.97
137_I152_L3.1540.96
213_D250_G3.1300.96
333_M342_L3.1040.96
507_N534_G3.0710.96
439_V466_T3.0620.96
85_F137_I3.0510.96
95_F108_G3.0480.96
537_S611_L2.9710.95
58_M151_A2.9630.95
678_I682_T2.9630.95
204_L260_G2.9530.95
20_L25_A2.9170.94
550_G577_A2.9120.94
116_I139_V2.8840.94
47_S57_I2.8600.94
9_A176_T2.8600.94
565_T609_F2.8550.94
64_C75_G2.8170.93
228_W231_H2.8080.93
636_L667_G2.7930.93
102_I108_G2.7560.93
42_R238_E2.7330.92
536_M653_M2.7300.92
532_M536_M2.7160.92
564_T591_H2.7150.92
25_A43_L2.7120.92
45_Y231_H2.7050.92
280_I286_F2.6580.91
676_Q698_L2.6030.90
20_L47_S2.5680.90
185_S343_S2.5170.89
352_L375_K2.5130.88
618_T658_K2.4660.87
155_S224_G2.4330.87
80_N83_E2.4310.87
84_M228_W2.4030.86
40_D43_L2.3710.85
501_L514_L2.3460.85
508_A555_H2.3330.84
553_T581_L2.3050.84
511_W579_R2.2870.83
663_M695_N2.2730.83
677_E695_N2.2470.82
643_K673_L2.2430.82
73_Y115_A2.2350.82
112_V141_V2.2170.81
639_M699_I2.2170.81
506_Y531_R2.2100.81
41_T231_H2.1950.80
204_L286_F2.1940.80
49_M239_V2.1370.78
635_H664_D2.1070.77
366_K371_D2.1030.77
459_L479_L2.0570.76
395_Y430_V2.0560.76
529_A684_S2.0470.75
466_T477_L2.0210.74
94_H138_R2.0020.74
605_A645_L2.0010.74
42_R46_Q1.9810.73
194_L594_I1.9610.72
547_S550_G1.9570.72
95_F141_V1.9400.71
541_D563_S1.9170.70
569_M625_M1.9070.70
33_G369_P1.9020.70
534_G559_G1.8840.69
155_S225_F1.8840.69
55_S158_G1.8650.68
343_S376_N1.8600.68
486_K566_T1.8530.67
558_L586_L1.8430.67
6_A20_L1.8410.67
608_Q647_R1.8310.67
510_L555_H1.8170.66
564_T581_L1.8150.66
85_F120_F1.8090.66
76_V150_I1.7850.64
76_V112_V1.7680.64
534_G555_H1.7630.63
70_L111_K1.7630.63
407_E410_A1.7510.63
157_D161_L1.7290.62
181_I345_F1.7290.62
532_M653_M1.7190.61
500_F579_R1.7190.61
508_A534_G1.7020.61
571_R595_Q1.6830.60
68_S71_D1.6760.59
581_L586_L1.6720.59
652_I699_I1.6610.59
614_I652_I1.6610.59
667_G673_L1.6540.58
410_A685_Q1.6500.58
169_G267_V1.6470.58
438_W478_V1.6440.58
115_A430_V1.6400.58
37_F57_I1.6310.57
64_C148_A1.6270.57
542_F591_H1.6230.57
72_L148_A1.6150.56
345_F349_P1.6120.56
80_N119_A1.6050.56
141_V150_I1.5930.55
674_K700_T1.5910.55
258_F286_F1.5910.55
550_G593_L1.5880.55
507_N558_L1.5710.54
508_A586_L1.5650.54
513_N516_D1.5630.54
550_G581_L1.5630.54
536_M698_L1.5590.54
10_R33_G1.5480.53
502_E511_W1.5430.53
6_A47_S1.5350.53
653_M698_L1.5140.51
94_H140_N1.5080.51
659_R690_N1.4990.51
345_F348_S1.4900.50
425_L566_T1.4770.50
553_T564_T1.4770.50
547_S684_S1.4760.50
10_R366_K1.4750.50
8_T673_L1.4670.49
581_L593_L1.4580.49
137_I228_W1.4580.49
91_F110_M1.4490.48
268_I288_V1.4300.47
553_T591_H1.4270.47
507_N531_R1.4260.47
4_L44_V1.4210.47
529_A629_F1.4200.47
280_I590_A1.4130.46
403_L410_A1.4090.46
304_G340_W1.4040.46
95_F143_L1.4040.46
267_V270_R1.3960.46
116_I472_I1.3960.46
658_K695_N1.3860.45
89_A229_A1.3770.45
247_A370_L1.3760.45
651_T698_L1.3660.44
60_P151_A1.3630.44
134_A222_R1.3590.44
566_T577_A1.3560.44
416_E436_A1.3520.43
533_L559_G1.3390.43
566_T684_S1.3370.43
500_F511_W1.3310.42
104_N110_M1.3300.42
108_G141_V1.3270.42
605_A609_F1.3230.42
99_N103_R1.3190.42
394_D425_L1.3160.42
651_T700_T1.3150.42
425_L547_S1.3010.41
639_M643_K1.2930.41
676_Q681_K1.2870.40
390_M393_E1.2870.40
529_A566_T1.2850.40
394_D429_N1.2830.40
618_T621_N1.2830.40
640_K670_K1.2800.40
91_F137_I1.2750.40
441_V466_T1.2720.40
106_Q110_M1.2640.39
137_I389_A1.2610.39
129_N558_L1.2510.39
77_Q122_R1.2480.39
679_T691_R1.2430.38
690_N693_I1.2410.38
614_I639_M1.2330.38
355_L385_D1.2330.38
614_I642_L1.2250.37
168_A267_V1.2240.37
677_E697_W1.2210.37
625_M645_L1.2210.37
322_L514_L1.2200.37
307_L450_I1.2190.37
685_Q688_A1.1960.36
4_L37_F1.1920.36
268_I286_F1.1870.36
280_I631_V1.1850.36
158_G174_K1.1770.35
8_T697_W1.1750.35
614_I629_F1.1710.35
434_R439_V1.1710.35
15_L180_A1.1690.35
285_T289_K1.1670.35
563_S647_R1.1660.35
667_G670_K1.1650.35
68_S439_V1.1650.35
529_A536_M1.1640.35
420_L470_L1.1630.35
365_A374_Q1.1600.34
312_Y367_N1.1570.34
504_T509_H1.1550.34
47_S586_L1.1540.34
184_R361_K1.1530.34
399_L425_L1.1500.34
536_M651_T1.1480.34
50_W215_A1.1470.34
346_S375_K1.1460.34
20_L37_F1.1450.34
6_A25_A1.1400.34
213_D242_E1.1380.33
345_F375_K1.1360.33
533_L653_M1.1290.33
67_Y71_D1.1170.33
459_L467_I1.1160.33
629_F697_W1.1140.32
510_L553_T1.1130.32
610_D647_R1.1120.32
260_G271_A1.1100.32
285_T288_V1.1080.32
37_F47_S1.1060.32
504_T534_G1.1060.32
643_K667_G1.1000.32
115_A148_A1.0980.32
478_V515_T1.0980.32
492_Q569_M1.0970.32
41_T84_M1.0940.32
571_R624_R1.0920.31
542_F611_L1.0900.31
510_L532_M1.0880.31
211_A250_G1.0870.31
532_M682_T1.0790.31
679_T683_L1.0750.31
502_E583_L1.0730.31
407_E446_P1.0720.31
504_T507_N1.0720.31
358_R375_K1.0680.30
210_L582_R1.0660.30
9_A429_N1.0660.30
653_M682_T1.0650.30
394_D427_E1.0640.30
592_R679_T1.0610.30
182_V185_S1.0610.30
653_M678_I1.0610.30
363_Y514_L1.0600.30
442_Q613_F1.0560.30
432_V609_F1.0550.30
409_W685_Q1.0550.30
395_Y462_I1.0530.30
442_Q598_C1.0520.30
397_N402_N1.0520.30
425_L469_V1.0520.30
308_S344_L1.0490.30
510_L547_S1.0450.30
50_W213_D1.0450.30
106_Q373_V1.0450.30
63_E147_T1.0430.29
79_I112_V1.0420.29
377_Y437_D1.0390.29
75_G148_A1.0380.29
15_L53_L1.0360.29
640_K673_L1.0350.29
573_Y616_P1.0350.29
77_Q119_A1.0290.29
79_I150_I1.0260.29
261_S289_K1.0250.29
410_A434_R1.0240.29
8_T13_E1.0190.28
275_A697_W1.0190.28
55_S618_T1.0170.28
142_W149_S1.0130.28
508_A554_V1.0110.28
79_I450_I1.0070.28
184_R363_Y1.0050.28
291_V329_L1.0050.28
389_A394_D1.0030.28
8_T363_Y1.0030.28
532_M678_I1.0010.28
91_F117_V0.9960.28
434_R470_L0.9910.27
571_R609_F0.9900.27
533_L631_V0.9860.27
69_D107_Y0.9860.27
261_S294_L0.9840.27
107_Y209_M0.9800.27
28_C116_I0.9790.27
326_H566_T0.9780.27
577_A642_L0.9780.27
169_G274_N0.9770.27
639_M652_I0.9770.27
165_R198_C0.9770.27
117_V138_R0.9750.27
399_L469_V0.9730.27
498_G677_E0.9730.27
86_N89_A0.9720.27
9_A55_S0.9700.27
158_G628_A0.9690.26
297_P337_F0.9670.26
55_S95_F0.9660.26
603_R641_D0.9640.26
97_G108_G0.9630.26
79_I115_A0.9630.26
286_F588_G0.9610.26
603_R637_A0.9540.26
362_Q683_L0.9510.26
177_L196_P0.9500.26
363_Y376_N0.9460.26
10_R361_K0.9430.25
39_G43_L0.9370.25
154_L228_W0.9370.25
506_Y534_G0.9360.25
200_S262_D0.9360.25
44_V399_L0.9360.25
291_V675_A0.9360.25
533_L611_L0.9340.25
462_I479_L0.9340.25
50_W243_A0.9340.25
138_R351_L0.9340.25
542_F552_A0.9340.25
91_F139_V0.9330.25
55_S394_D0.9290.25
656_N695_N0.9270.25
450_I455_A0.9260.25
204_L284_I0.9260.25
96_S142_W0.9210.25
392_A465_A0.9190.25
61_L152_L0.9190.25
528_I547_S0.9160.24
528_I684_S0.9160.24
423_A622_S0.9140.24
507_N551_S0.9120.24
622_S625_M0.9110.24
352_L377_Y0.9100.24
658_K692_Q0.9080.24
63_E400_R0.9070.24
628_A633_R0.9070.24
467_I470_L0.9070.24
629_F658_K0.9060.24
8_T643_K0.9050.24
42_R235_I0.9020.24
369_P406_F0.9000.24
76_V89_A0.8990.24
247_A628_A0.8980.24
53_L183_M0.8960.24
175_E311_P0.8950.24
223_W308_S0.8940.24
278_A372_C0.8920.24
77_Q80_N0.8890.24
396_T469_V0.8880.23
494_L609_F0.8860.23
286_F308_S0.8850.23
115_A141_V0.8830.23
64_C542_F0.8830.23
437_D471_G0.8810.23
437_D450_I0.8800.23
439_V472_I0.8800.23
571_R678_I0.8780.23
41_T228_W0.8750.23
174_K312_Y0.8740.23
526_H655_S0.8740.23
508_A581_L0.8730.23
232_D235_I0.8710.23
154_L197_M0.8680.23
127_R135_P0.8670.23
555_H642_L0.8660.23
70_L74_L0.8660.23
258_F506_Y0.8660.23
502_E509_H0.8620.23
223_W652_I0.8620.23
160_H310_P0.8610.23
13_E618_T0.8610.23
172_P309_N0.8590.22
97_G103_R0.8590.22
446_P455_A0.8580.22
55_S629_F0.8570.22
93_V450_I0.8570.22
542_F682_T0.8560.22
177_L618_T0.8560.22
93_V562_R0.8560.22
355_L377_Y0.8560.22
93_V112_V0.8560.22
564_T588_G0.8550.22
542_F581_L0.8540.22
97_G105_S0.8530.22
59_L230_Q0.8520.22
33_G223_W0.8510.22
668_L699_I0.8510.22
322_L346_S0.8500.22
280_I283_L0.8490.22
529_A696_C0.8490.22
376_N425_L0.8480.22
164_Y485_Q0.8460.22
471_G476_K0.8440.22
565_T594_I0.8430.22
157_D224_G0.8420.22
555_H696_C0.8410.22
57_I155_S0.8400.22
441_V467_I0.8390.22
261_S291_V0.8380.22
64_C697_W0.8360.22
428_Y461_D0.8330.22
185_S429_N0.8310.22
289_K699_I0.8300.21
31_V140_N0.8300.21
305_T629_F0.8300.21
4_L623_K0.8290.21
116_I281_G0.8290.21
184_R427_E0.8270.21
103_R609_F0.8250.21
276_R486_K0.8250.21
76_V454_K0.8240.21
165_R195_D0.8240.21
229_A594_I0.8230.21
366_K369_P0.8220.21
485_Q492_Q0.8210.21
242_E246_R0.8190.21
284_I377_Y0.8180.21
536_M611_L0.8180.21
139_V152_L0.8160.21
517_Y573_Y0.8150.21
185_S448_K0.8150.21
677_E684_S0.8140.21
263_S291_V0.8130.21
239_V675_A0.8120.21
4_L154_L0.8120.21
175_E367_N0.8110.21
39_G484_R0.8110.21
265_A268_I0.8090.21
30_V553_T0.8090.21
73_Y118_D0.8080.21
175_E202_T0.8080.21
310_P315_R0.8070.21
10_R363_Y0.8070.21
485_Q490_Q0.8070.21
394_D461_D0.8070.21
66_V150_I0.8060.21
314_E317_D0.8050.21
6_A566_T0.8020.21
261_S268_I0.8020.21
459_L466_T0.8010.21
485_Q516_D0.8010.21
130_V342_L0.8010.21
510_L652_I0.7990.20
86_N234_A0.7990.20
149_S676_Q0.7980.20
8_T372_C0.7980.20
33_G660_G0.7960.20
395_Y683_L0.7950.20
347_A420_L0.7930.20
511_W586_L0.7860.20
566_T696_C0.7860.20
370_L498_G0.7840.20
438_W476_K0.7840.20
14_E33_G0.7820.20
510_L554_V0.7810.20
542_F678_I0.7810.20
173_I472_I0.7810.20
510_L551_S0.7800.20
112_V148_A0.7790.20
92_A135_P0.7790.20
85_F89_A0.7780.20
290_D355_L0.7780.20
58_M140_N0.7770.20
451_D454_K0.7770.20
141_V579_R0.7730.20
667_G675_A0.7730.20
130_V137_I0.7720.20
25_A37_F0.7700.20
264_D553_T0.7700.20
7_S153_D0.7690.20
520_T573_Y0.7680.19
553_T641_D0.7680.19
214_R247_A0.7660.19
683_L691_R0.7660.19
683_L695_N0.7650.19
411_R418_Y0.7640.19
116_I255_S0.7620.19
120_F528_I0.7620.19
8_T142_W0.7600.19
72_L81_W0.7600.19
6_A547_S0.7600.19
262_D337_F0.7590.19
612_I646_L0.7580.19
9_A104_N0.7570.19
566_T629_F0.7570.19
590_A677_E0.7550.19
203_L275_A0.7550.19
4_L40_D0.7540.19
529_A547_S0.7520.19
182_V305_T0.7520.19
53_L182_V0.7520.19
104_N430_V0.7500.19
444_Y630_D0.7500.19
83_E446_P0.7500.19
485_Q488_K0.7500.19
286_F359_A0.7500.19
261_S287_E0.7500.19
164_Y490_Q0.7440.19
158_G164_Y0.7440.19
425_L684_S0.7430.19
174_K309_N0.7430.19
85_F91_F0.7420.19
261_S345_F0.7420.19
586_L591_H0.7420.19
338_G384_P0.7410.19
154_L470_L0.7400.19
388_P394_D0.7390.19
164_Y313_G0.7380.19
364_K373_V0.7380.19
20_L137_I0.7380.19
152_L459_L0.7360.18
332_I336_Q0.7360.18
91_F120_F0.7350.18
441_V463_I0.7340.18
194_L486_K0.7340.18
331_R691_R0.7330.18
213_D247_A0.7330.18
118_D127_R0.7320.18
581_L591_H0.7320.18
17_K28_C0.7320.18
597_D600_A0.7300.18
163_G187_W0.7300.18
142_W339_G0.7290.18
643_K675_A0.7290.18
692_Q695_N0.7280.18
5_F57_I0.7270.18
84_M231_H0.7270.18
569_M695_N0.7260.18
174_K340_W0.7250.18
76_V140_N0.7240.18
202_T367_N0.7230.18
119_A535_Q0.7230.18
342_L609_F0.7220.18
321_A432_V0.7210.18
265_A280_I0.7210.18
354_C618_T0.7210.18
174_K197_M0.7210.18
18_T21_E0.7190.18
4_L405_K0.7190.18
237_Q450_I0.7190.18
60_P111_K0.7170.18
517_Y616_P0.7170.18
143_L271_A0.7170.18
310_P313_G0.7170.18
108_G143_L0.7160.18
572_T616_P0.7160.18
50_W236_W0.7150.18
41_T44_V0.7140.18
105_S169_G0.7140.18
73_Y111_K0.7130.18
395_Y631_V0.7120.18
663_M690_N0.7120.18
405_K656_N0.7110.18
222_R256_S0.7110.18
190_G306_V0.7080.18
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261_S285_T0.7070.18
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149_S415_I0.7030.18
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41_T235_I0.7030.18
209_M224_G0.7010.17
585_G677_E0.7000.17
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130_V306_V0.6970.17
247_A362_Q0.6970.17
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450_I664_D0.6860.17
537_S653_M0.6840.17
362_Q461_D0.6840.17
625_M628_A0.6830.17
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309_N315_R0.6820.17
542_F553_T0.6820.17
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215_A236_W0.6300.16
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271_A340_W0.6290.16
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55_S353_S0.6280.15
557_G679_T0.6280.15
197_M697_W0.6280.15
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345_F451_D0.6260.15
579_R593_L0.6260.15
503_V602_L0.6260.15
42_R129_N0.6260.15
441_V627_D0.6250.15
85_F139_V0.6250.15
100_D149_S0.6250.15
143_L204_L0.6250.15
104_N143_L0.6240.15
643_K684_S0.6240.15
231_H467_I0.6230.15
84_M229_A0.6220.15
93_V99_N0.6220.15
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564_T586_L0.6210.15
114_D128_P0.6190.15
460_F483_E0.6180.15
388_P465_A0.6180.15
175_E312_Y0.6180.15
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92_A241_A0.6170.15
432_V631_V0.6160.15
161_L416_E0.6160.15
129_N461_D0.6150.15
210_L592_R0.6140.15
536_M678_I0.6140.15
484_R670_K0.6140.15
68_S609_F0.6140.15
510_L581_L0.6130.15
397_N485_Q0.6130.15
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209_M448_K0.6120.15
370_L514_L0.6120.15
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75_G190_G0.6020.15
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18_T302_P0.6010.15
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31_V598_C0.5990.15
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202_T310_P0.5670.14
643_K668_L0.5660.14
65_K147_T0.5650.14
208_A271_A0.5640.14
581_L585_G0.5630.14
40_D466_T0.5630.14
102_I314_E0.5630.14
186_G438_W0.5630.14
87_P107_Y0.5610.14
380_A384_P0.5610.14
12_L417_C0.5580.14
642_L645_L0.5580.14
639_M642_L0.5580.14
653_M696_C0.5570.14
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216_P572_T0.5550.14
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510_L534_G0.5540.14
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63_E70_L0.5540.14
138_R151_A0.5540.14
152_L207_A0.5540.14
550_G690_N0.5520.14
361_K621_N0.5520.14
194_L332_I0.5510.14
529_A569_M0.5510.14
307_L415_I0.5500.14
244_Q504_T0.5500.14
472_I550_G0.5500.14
111_K498_G0.5500.14
353_S377_Y0.5500.14
500_F571_R0.5490.14
89_A227_G0.5490.14
363_Y374_Q0.5490.14
110_M347_A0.5480.14
529_A593_L0.5480.14
93_V148_A0.5480.14
41_T318_S0.5480.14
550_G553_T0.5480.14
141_V535_Q0.5480.14
322_L409_W0.5470.13
205_I474_P0.5450.13
16_L19_E0.5450.13
450_I613_F0.5450.13
452_A697_W0.5440.13
326_H344_L0.5430.13
596_A649_G0.5430.13
57_I651_T0.5430.13
175_E309_N0.5420.13
199_G315_R0.5410.13
8_T376_N0.5410.13
122_R477_L0.5400.13
360_D378_H0.5390.13
107_Y133_D0.5390.13
182_V467_I0.5390.13
116_I214_R0.5380.13
116_I457_Q0.5380.13
403_L470_L0.5380.13
346_S351_L0.5380.13
199_G202_T0.5370.13
405_K425_L0.5370.13
97_G100_D0.5360.13
281_G446_P0.5360.13
18_T539_G0.5350.13
85_F429_N0.5350.13
192_P307_L0.5340.13
645_L673_L0.5340.13
86_N152_L0.5330.13
129_N508_A0.5330.13
98_L104_N0.5320.13
52_R56_R0.5320.13
111_K323_I0.5320.13
99_N143_L0.5320.13
532_M651_T0.5320.13
146_E332_I0.5310.13
200_S309_N0.5310.13
265_A446_P0.5310.13
163_G202_T0.5300.13
15_L363_Y0.5300.13
182_V429_N0.5300.13
394_D684_S0.5290.13
559_G579_R0.5290.13
529_A532_M0.5290.13
119_A123_K0.5290.13
476_K627_D0.5280.13
175_E196_P0.5280.13
124_N579_R0.5270.13
71_D74_L0.5270.13
169_G363_Y0.5260.13
404_K492_Q0.5260.13
9_A95_F0.5250.13
57_I692_Q0.5250.13
10_R184_R0.5250.13
146_E441_V0.5240.13
102_I480_K0.5240.13
12_L569_M0.5240.13
132_R692_Q0.5240.13
69_D111_K0.5240.13
537_S553_T0.5230.13
423_A625_M0.5220.13
114_D118_D0.5220.13
223_W559_G0.5220.13
489_N599_L0.5220.13
577_A586_L0.5210.13
158_G348_S0.5210.13
35_V109_A0.5210.13
7_S55_S0.5200.13
615_D657_N0.5200.13
344_L639_M0.5200.13
160_H316_L0.5200.13
90_T232_D0.5200.13
189_P465_A0.5200.13
194_L413_E0.5190.13
13_E552_A0.5180.13
33_G563_S0.5180.13
220_R417_C0.5180.13
93_V499_E0.5170.13
195_D311_P0.5170.13
212_T381_E0.5170.13
315_R340_W0.5170.13
13_E177_L0.5160.13
29_Q68_S0.5160.13
64_C181_I0.5160.13
431_A520_T0.5160.13
129_N496_E0.5150.13
33_G110_M0.5140.13
86_N486_K0.5140.13
127_R136_D0.5140.13
495_G498_G0.5140.13
125_L457_Q0.5130.13
290_D344_L0.5130.13
186_G678_I0.5130.13
97_G222_R0.5130.13
532_M681_K0.5130.13
280_I596_A0.5120.13
286_F477_L0.5120.13
389_A649_G0.5120.13
306_V609_F0.5110.13
207_A258_F0.5110.13
362_Q439_V0.5110.13
236_W243_A0.5100.13
184_R428_Y0.5100.13
182_V236_W0.5090.13
97_G658_K0.5090.13
160_H311_P0.5080.13
174_K346_S0.5070.13
120_F137_I0.5070.13
222_R679_T0.5070.13
20_L392_A0.5060.13
307_L675_A0.5060.13
196_P311_P0.5050.13
18_T123_K0.5050.13
65_K662_R0.5050.13
272_R386_S0.5050.13
60_P581_L0.5050.13
44_V321_A0.5050.13
150_I649_G0.5050.13
399_L466_T0.5040.13
245_T249_K0.5040.13
122_R207_A0.5030.13
175_E326_H0.5030.13
198_C315_R0.5030.13
550_G611_L0.5020.12
205_I679_T0.5020.12
115_A462_I0.5020.12
48_L57_I0.5010.12
152_L473_A0.5010.12
481_T566_T0.5010.12
21_E116_I0.5000.12
46_Q239_V0.5000.12
498_G592_R0.5000.12
609_F697_W0.5000.12
247_A322_L0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3v97A 1 0.9501 100 0.461 Contact Map
3lduA 1 0.5342 100 0.701 Contact Map
3ldgA 1 0.5285 100 0.703 Contact Map
3k0bA 1 0.5228 100 0.708 Contact Map
3tm4A 1 0.4672 100 0.793 Contact Map
3tmaA 2 0.4587 100 0.825 Contact Map
2b78A 1 0.5014 100 0.853 Contact Map
3vseA 1 0.5242 100 0.857 Contact Map
3c0kA 2 0.5128 100 0.873 Contact Map
1wxxA 2 0.5071 100 0.873 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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