GREMLIN Database
YCBV - Uncharacterized fimbrial-like protein YcbV
UniProt: P75860 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13714
Length: 171 (160)
Sequences: 3497 (2776)
Seq/√Len: 219.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
114_I146_A3.0581.00
99_M113_A2.9421.00
115_A147_Q2.8801.00
110_S156_Q2.8531.00
100_L126_L2.7461.00
117_L147_Q2.6861.00
115_A149_R2.6831.00
84_V168_L2.6621.00
39_V76_D2.6381.00
71_I141_P2.5791.00
148_L160_V2.5091.00
41_A75_Q2.4401.00
102_I160_V2.2261.00
121_K145_Y2.1741.00
73_N141_P2.1271.00
114_I162_A2.0431.00
60_S63_N2.0081.00
100_L164_A1.9891.00
71_I143_T1.9771.00
118_D122_I1.9071.00
17_G21_F1.8651.00
115_A123_L1.8591.00
99_M149_R1.8511.00
111_G155_V1.8251.00
67_E147_Q1.8221.00
64_Y115_A1.7911.00
125_P128_Q1.7641.00
90_G100_L1.7551.00
41_A44_S1.6361.00
69_S145_Y1.5991.00
41_A73_N1.5691.00
89_S167_V1.5691.00
90_G93_D1.5661.00
54_V65_G1.5631.00
52_G68_K1.4981.00
135_L140_V1.4961.00
93_D151_V1.4521.00
89_S127_N1.4431.00
52_G160_V1.4201.00
52_G66_P1.4091.00
85_D169_H1.4061.00
70_F116_I1.3971.00
98_E125_P1.3891.00
32_S53_D1.3891.00
47_I72_I1.3841.00
10_F13_G1.3721.00
104_S159_K1.3721.00
59_F150_P1.3721.00
51_L148_L1.3711.00
69_S143_T1.3481.00
64_Y147_Q1.3101.00
44_S73_N1.2571.00
44_S47_I1.2451.00
49_V70_F1.2241.00
61_H150_P1.2191.00
92_P98_E1.1861.00
83_T134_S1.1831.00
15_T18_C1.1831.00
87_T129_A1.1621.00
11_L14_L1.1611.00
116_I164_A1.1291.00
51_L160_V1.1271.00
28_N163_S1.1251.00
60_S150_P1.1221.00
64_Y117_L1.1021.00
67_E145_Y1.0791.00
39_V75_Q1.0681.00
88_F116_I1.0651.00
10_F14_L1.0641.00
64_Y149_R1.0581.00
35_R56_L1.0571.00
12_L15_T1.0551.00
88_F144_F1.0481.00
86_V142_L1.0481.00
25_G166_F1.0461.00
99_M115_A1.0441.00
150_P155_V1.0421.00
119_D143_T1.0301.00
14_L18_C1.0161.00
59_F112_L1.0071.00
25_G29_I1.0071.00
72_I166_F1.0041.00
130_S144_F1.0041.00
84_V135_L0.9961.00
51_L114_I0.9891.00
8_I11_L0.9751.00
87_T169_H0.9681.00
92_P126_L0.9591.00
84_V140_V0.9481.00
17_G20_L0.9461.00
54_V160_V0.9431.00
42_Q45_K0.9421.00
109_A112_L0.9381.00
93_D101_S0.9381.00
117_L145_Y0.9331.00
58_R65_G0.9260.99
55_S58_R0.9250.99
59_F151_V0.9220.99
59_F63_N0.9170.99
47_I166_F0.9030.99
54_V59_F0.8980.99
88_F166_F0.8960.99
113_A151_V0.8920.99
42_Q47_I0.8910.99
103_E161_N0.8800.99
18_C21_F0.8730.99
16_W20_L0.8620.99
100_L162_A0.8590.99
59_F155_V0.8490.99
9_L12_L0.8450.99
63_N150_P0.8440.99
35_R78_G0.8430.99
13_G17_G0.8420.99
54_V148_L0.8380.99
112_L148_L0.8310.99
150_P153_S0.8200.99
20_L23_H0.8080.99
105_G159_K0.8080.99
20_L24_D0.8060.99
30_S50_Q0.8050.99
90_G94_G0.7960.98
51_L68_K0.7920.98
91_T101_S0.7880.98
130_S133_Y0.7820.98
87_T128_Q0.7740.98
126_L144_F0.7730.98
26_T46_Q0.7720.98
37_T148_L0.7690.98
117_L123_L0.7670.98
102_I109_A0.7600.98
114_I160_V0.7570.98
124_I130_S0.7550.98
19_E23_H0.7510.98
50_Q68_K0.7470.98
103_E163_S0.7470.98
56_L157_S0.7470.98
30_S48_N0.7460.98
116_I126_L0.7390.97
86_V168_L0.7380.97
33_F54_V0.7370.97
13_G16_W0.7320.97
50_Q148_L0.7280.97
64_Y67_E0.7280.97
8_I15_T0.7260.97
21_F24_D0.7250.97
85_D129_A0.7160.97
122_I131_K0.7090.97
51_L115_A0.7090.97
18_C22_A0.7080.97
111_G152_N0.7050.97
73_N139_K0.6970.96
12_L21_F0.6960.96
111_G154_D0.6870.96
51_L146_A0.6870.96
96_Q99_M0.6850.96
14_L17_G0.6850.96
95_V98_E0.6820.96
16_W19_E0.6820.96
124_I144_F0.6800.96
78_G117_L0.6680.95
93_D97_S0.6680.95
35_R82_S0.6680.95
9_L13_G0.6670.95
85_D130_S0.6630.95
67_E117_L0.6600.95
150_P154_D0.6600.95
8_I13_G0.6540.95
83_T132_D0.6520.95
102_I161_N0.6500.95
93_D113_A0.6440.94
8_I21_F0.6390.94
51_L147_Q0.6350.94
75_Q139_K0.6310.94
52_G161_N0.6270.94
128_Q131_K0.6260.94
89_S165_T0.6170.93
47_I90_G0.6160.93
63_N153_S0.6160.93
148_L161_N0.6120.93
11_L19_E0.6080.93
149_R153_S0.6010.92
126_L162_A0.6000.92
71_I92_P0.5940.92
59_F160_V0.5910.92
65_G147_Q0.5830.91
144_F166_F0.5800.91
135_L138_G0.5770.91
27_V164_A0.5770.91
39_V78_G0.5760.91
134_S137_S0.5760.91
65_G148_L0.5750.90
15_T19_E0.5720.90
117_L149_R0.5720.90
51_L70_F0.5710.90
93_D152_N0.5700.90
28_N46_Q0.5690.90
11_L15_T0.5690.90
58_R66_P0.5660.90
25_G32_S0.5640.90
111_G151_V0.5610.89
8_I17_G0.5610.89
12_L16_W0.5600.89
28_N48_N0.5590.89
50_Q53_D0.5560.89
59_F148_L0.5550.89
48_N165_T0.5550.89
18_C23_H0.5530.89
136_H140_V0.5500.88
120_A145_Y0.5500.88
65_G68_K0.5480.88
37_T78_G0.5480.88
28_N161_N0.5470.88
12_L20_L0.5410.88
16_W21_F0.5340.87
9_L16_W0.5320.87
102_I112_L0.5300.87
134_S139_K0.5300.87
123_L126_L0.5300.87
95_V152_N0.5300.87
120_A133_Y0.5300.87
97_S100_L0.5300.87
44_S48_N0.5290.86
49_V146_A0.5270.86
17_G22_A0.5220.86
8_I12_L0.5210.86
56_L155_V0.5200.85
87_T168_L0.5190.85
10_F16_W0.5170.85
132_D135_L0.5170.85
9_L21_F0.5160.85
96_Q127_N0.5140.85
125_P130_S0.5080.84
33_F102_I0.5070.84
111_G153_S0.5060.84
59_F111_G0.5050.84
74_L84_V0.5030.84
46_Q166_F0.5030.84
83_T137_S0.5030.84
103_E162_A0.5010.83
163_S168_L0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xg5B 1 0.8129 100 0.245 Contact Map
2jmrA 1 0.8772 100 0.247 Contact Map
2uy6B 2 0.8363 100 0.276 Contact Map
2jtyA 1 0.8947 100 0.279 Contact Map
1pdkB 1 0.8012 100 0.304 Contact Map
3bwuF 1 0.7193 100 0.346 Contact Map
2w07B 1 0.6842 100 0.365 Contact Map
5afoA 1 0.9591 99.9 0.384 Contact Map
4dwhB 1 0.7719 99.9 0.385 Contact Map
3bfqG 1 0.7544 99.9 0.393 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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