GREMLIN Database
ELFD - Probable fimbrial chaperone protein ElfD
UniProt: P75856 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13710
Length: 233 (210)
Sequences: 2878 (2180)
Seq/√Len: 150.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
179_T194_M3.2601.00
67_V141_L3.2241.00
177_F196_S3.0131.00
171_S200_K2.9591.00
42_S45_E2.9331.00
111_L194_M2.8871.00
34_L139_I2.8661.00
196_S199_D2.8571.00
108_R198_F2.8341.00
104_L112_F2.7511.00
169_T200_K2.5901.00
161_C170_V2.5841.00
169_T202_Q2.5791.00
160_R171_S2.5671.00
39_L48_I2.5271.00
61_Y118_A2.5221.00
39_L114_T2.4471.00
39_L97_I2.4161.00
167_M202_Q2.3911.00
154_E157_A2.3751.00
142_F194_M2.3711.00
44_G146_K2.3521.00
220_N226_T2.3031.00
170_V203_F2.2241.00
142_F177_F2.1331.00
60_P88_N2.0771.00
68_M138_V2.0521.00
66_W115_S2.0121.00
162_T169_T1.9841.00
42_S48_I1.8891.00
117_R136_Q1.8831.00
65_S95_L1.8371.00
105_A110_T1.8331.00
155_A178_I1.8301.00
60_P86_V1.7521.00
148_L176_Y1.7321.00
78_F97_I1.7141.00
80_I95_L1.6481.00
34_L116_V1.6221.00
68_M115_S1.6151.00
158_K174_T1.6041.00
155_A218_T1.5981.00
88_N91_N1.5921.00
115_S138_V1.5481.00
159_L170_V1.5411.00
159_L178_I1.5331.00
67_V76_A1.5161.00
178_I218_T1.5111.00
164_S169_T1.5101.00
182_D217_R1.4721.00
111_L142_F1.4721.00
151_P154_E1.4531.00
220_N224_A1.4501.00
99_Y102_A1.4251.00
159_L180_L1.4201.00
63_I85_F1.4191.00
162_T171_S1.3911.00
50_L114_T1.3881.00
41_Y48_I1.3581.00
43_E106_K1.3431.00
47_Q96_R1.3311.00
78_F141_L1.3201.00
152_L155_A1.3051.00
51_G92_E1.3051.00
69_T73_K1.3021.00
184_K215_T1.2931.00
58_D90_A1.2751.00
39_L139_I1.2681.00
105_A108_R1.2561.00
161_C216_Y1.2551.00
195_I201_Y1.2451.00
56_S118_A1.2361.00
111_L179_T1.2301.00
167_M204_S1.2271.00
175_P198_F1.2051.00
80_I97_I1.2011.00
34_L50_L1.1901.00
179_T218_T1.1791.00
164_S167_M1.1691.00
218_T226_T1.1661.00
43_E146_K1.1661.00
156_P178_I1.1641.00
66_W138_V1.1371.00
52_V87_L1.1301.00
181_T225_E1.1170.99
99_Y143_W1.1150.99
99_Y103_P1.1040.99
97_I141_L1.0910.99
123_T130_T1.0850.99
118_A135_T1.0550.99
114_T141_L1.0550.99
168_V205_L1.0530.99
163_S166_D1.0430.99
123_T132_K1.0400.99
68_M72_N1.0370.99
31_G118_A1.0350.99
113_F138_V1.0330.99
14_L22_S1.0290.99
85_F93_N1.0240.99
33_G36_A1.0190.99
35_A51_G1.0120.99
66_W117_R1.0120.99
32_I63_I1.0100.99
95_L114_T1.0080.99
150_Y176_Y0.9980.99
53_R92_E0.9960.99
41_Y98_M0.9950.99
43_E143_W0.9930.99
32_I87_L0.9890.99
36_A50_L0.9890.99
217_R225_E0.9820.99
184_K189_V0.9750.99
93_N117_R0.9710.98
34_L52_V0.9660.98
158_K173_P0.9640.98
156_P216_Y0.9430.98
180_L195_I0.9420.98
56_S61_Y0.9410.98
71_D74_K0.9380.98
18_L21_C0.9270.98
180_L218_T0.9240.98
87_L92_E0.9210.98
68_M113_F0.9140.98
95_L116_V0.9050.98
184_K187_G0.8900.97
67_V80_I0.8860.97
38_R144_R0.8820.97
35_A92_E0.8810.97
80_I114_T0.8750.97
140_K219_I0.8640.97
154_E158_K0.8460.96
93_N118_A0.8390.96
56_S59_V0.8390.96
65_S116_V0.8370.96
41_Y78_F0.8350.96
168_V183_L0.8280.96
181_T219_I0.8260.96
107_D198_F0.8250.96
52_V63_I0.8220.96
171_S198_F0.8170.96
113_F117_R0.8160.96
109_E144_R0.8120.95
134_A161_C0.8070.95
160_R173_P0.8000.95
65_S80_I0.7970.95
177_F197_P0.7960.95
39_L50_L0.7920.95
147_G150_Y0.7890.95
156_P218_T0.7840.95
112_F143_W0.7800.94
85_F95_L0.7780.94
104_L108_R0.7770.94
152_L178_I0.7720.94
61_Y117_R0.7720.94
180_L224_A0.7690.94
87_L93_N0.7550.93
152_L156_P0.7540.93
111_L177_F0.7450.93
185_I214_V0.7370.93
67_V119_V0.7300.92
36_A39_L0.7280.92
40_V144_R0.7230.92
38_R140_K0.7220.92
51_G84_L0.7200.92
38_R145_P0.7170.91
115_S136_Q0.7170.91
69_T75_S0.7160.91
150_Y155_A0.7150.91
151_P158_K0.7090.91
161_C183_L0.7090.91
70_P113_F0.7080.91
31_G61_Y0.7070.91
116_V139_I0.7040.91
115_S140_K0.7000.91
64_Q117_R0.6980.90
185_I213_S0.6970.90
33_G137_S0.6910.90
179_T192_N0.6910.90
164_S202_Q0.6890.90
63_I87_L0.6890.90
31_G55_T0.6880.90
16_A19_L0.6850.90
188_K208_G0.6850.90
106_K147_G0.6800.89
87_L91_N0.6790.89
150_Y154_E0.6760.89
168_V214_V0.6750.89
33_G55_T0.6740.89
70_P111_L0.6730.89
161_C168_V0.6700.89
61_Y65_S0.6690.88
205_L209_A0.6690.88
69_T76_A0.6680.88
97_I114_T0.6660.88
19_L26_A0.6660.88
15_T23_S0.6590.88
192_N203_F0.6580.88
167_M205_L0.6560.87
55_T121_S0.6560.87
25_W29_K0.6550.87
183_L203_F0.6540.87
140_K179_T0.6520.87
110_T143_W0.6470.87
84_L92_E0.6470.87
156_P159_L0.6460.87
14_L18_L0.6450.87
187_G215_T0.6410.86
118_A134_A0.6410.86
52_V121_S0.6410.86
65_S93_N0.6390.86
205_L208_G0.6390.86
113_F140_K0.6380.86
140_K144_R0.6370.86
60_P121_S0.6350.86
107_D144_R0.6320.85
17_I20_S0.6310.85
108_R145_P0.6310.85
14_L17_I0.6300.85
156_P174_T0.6300.85
20_S25_W0.6240.85
104_L107_D0.6220.85
19_L22_S0.6210.84
42_S142_F0.6210.84
23_S189_V0.6210.84
27_A209_A0.6200.84
96_R120_P0.6200.84
32_I61_Y0.6180.84
113_F179_T0.6160.84
216_Y226_T0.6160.84
34_L62_L0.6130.84
41_Y99_Y0.6110.84
24_A162_T0.6080.83
41_Y46_E0.6080.83
166_D207_K0.6070.83
34_L55_T0.6060.83
135_T192_N0.6050.83
129_N132_K0.5960.82
78_F110_T0.5960.82
24_A28_G0.5940.82
146_K149_A0.5930.82
166_D204_S0.5910.81
107_D110_T0.5890.81
70_P138_V0.5890.81
186_G191_K0.5870.81
41_Y45_E0.5870.81
83_P119_V0.5800.80
186_G212_S0.5770.80
104_L110_T0.5770.80
30_G33_G0.5760.80
131_L138_V0.5760.80
156_P173_P0.5740.80
182_D189_V0.5740.80
15_T18_L0.5740.80
188_K191_K0.5730.79
62_L117_R0.5730.79
144_R197_P0.5730.79
37_T144_R0.5720.79
190_V208_G0.5710.79
78_F143_W0.5710.79
38_R221_D0.5660.79
103_P106_K0.5630.78
14_L19_L0.5600.78
18_L29_K0.5570.78
56_S117_R0.5560.77
98_M197_P0.5550.77
29_K168_V0.5540.77
27_A207_K0.5530.77
62_L176_Y0.5500.77
65_S85_F0.5490.77
113_F116_V0.5490.77
183_L205_L0.5480.76
170_V195_I0.5460.76
21_C191_K0.5450.76
26_A207_K0.5440.76
124_K160_R0.5440.76
145_P197_P0.5420.76
201_Y204_S0.5420.76
61_Y87_L0.5410.75
52_V116_V0.5400.75
180_L216_Y0.5400.75
195_I199_D0.5390.75
19_L25_W0.5360.75
22_S211_N0.5350.75
148_L175_P0.5310.74
26_A29_K0.5300.74
119_V135_T0.5300.74
122_T132_K0.5300.74
159_L218_T0.5290.74
27_A204_S0.5270.74
64_Q96_R0.5250.73
184_K217_R0.5250.73
219_I226_T0.5240.73
120_P134_A0.5230.73
118_A136_Q0.5210.73
20_S24_A0.5180.72
51_G117_R0.5160.72
180_L183_L0.5150.72
50_L97_I0.5130.72
77_D110_T0.5130.72
25_W28_G0.5120.71
68_M133_I0.5110.71
62_L118_A0.5110.71
188_K211_N0.5110.71
68_M117_R0.5100.71
113_F136_Q0.5090.71
161_C214_V0.5070.71
67_V112_F0.5070.71
168_V202_Q0.5060.71
151_P156_P0.5040.70
45_E102_A0.5030.70
153_G157_A0.5010.70
49_S133_I0.5010.70
14_L26_A0.5010.70
166_D208_G0.5010.70
161_C194_M0.5000.70
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1l4iA 2 0.8155 100 0.147 Contact Map
2co7B 1 0.8412 100 0.149 Contact Map
1klfA 1 0.867 100 0.149 Contact Map
2xg5A 1 0.8455 100 0.181 Contact Map
3q48A 1 0.7897 100 0.185 Contact Map
3gfuC 1 0.8283 100 0.193 Contact Map
4ay0A 2 0.8026 100 0.196 Contact Map
4djmA 1 0.8541 100 0.198 Contact Map
4ncdA 2 0.7983 100 0.267 Contact Map
1mspA 3 0.4764 91.7 0.917 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0083 seconds.