MACB - ECOLI - GREMLIN Contacts

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MACB - Macrolide export ATP-binding/permease protein MacB

UniProt:	P75831	Sequences: MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVTGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13695
Length:	648 (627)
Sequences:	1394 (1031)
Seq/√Len:	41.2

ECOLI - MACB RBSA
BACSU - TAGH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
6_E	30_D	8.442	1.00
38_A	210_A	8.222	1.00
9_D	26_G	7.092	1.00
130_Q	135_E	6.628	1.00
131_R	189_Q	6.347	1.00
7_L	10_I	6.319	1.00
64_T	71_D	6.307	1.00
25_K	220_E	6.161	1.00
9_D	28_S	5.769	1.00
123_L	127_E	5.255	1.00
127_E	131_R	5.102	1.00
11_R	26_G	4.904	1.00
22_E	25_K	4.753	1.00
137_R	140_Y	4.606	1.00
126_Q	138_T	4.387	1.00
31_I	198_I	4.063	1.00
8_K	30_D	3.742	1.00
640_D	643_D	3.732	1.00
454_L	458_T	3.663	1.00
76_D	79_A	3.661	1.00
454_L	459_M	3.387	1.00
183_V	186_I	3.279	1.00
102_T	105_Q	3.112	1.00
454_L	469_L	3.099	1.00
177_S	217_R	3.076	1.00
208_A	213_V	2.977	1.00
162_G	195_H	2.975	1.00
567_D	570_Q	2.927	1.00
191_R	211_E	2.915	1.00
404_L	424_I	2.792	1.00
11_R	22_E	2.743	1.00
388_N	434_I	2.741	1.00
5_L	67_V	2.685	1.00
107_V	129_L	2.625	1.00
40_V	204_P	2.610	1.00
13_S	22_E	2.603	1.00
454_L	463_V	2.602	1.00
13_S	61_T	2.538	1.00
155_I	183_V	2.484	1.00
615_L	619_L	2.458	1.00
335_D	338_A	2.447	1.00
108_E	122_L	2.423	1.00
131_R	193_R	2.394	1.00
216_I	221_I	2.316	1.00
163_G	195_H	2.306	1.00
13_S	20_Q	2.283	1.00
6_E	66_R	2.275	1.00
70_Q	79_A	2.240	1.00
478_E	481_D	2.236	1.00
104_E	125_A	2.221	1.00
105_Q	263_R	2.195	1.00
95_Y	174_A	2.195	1.00
15_P	20_Q	2.184	1.00
215_E	223_R	2.161	0.99
135_E	138_T	2.110	0.99
458_T	469_L	2.102	0.99
419_V	422_E	2.097	0.99
188_H	209_Q	2.021	0.99
204_P	215_E	2.011	0.99
11_R	62_S	2.007	0.99
140_Y	144_Q	1.959	0.99
585_A	589_T	1.929	0.99
344_W	485_A	1.899	0.99
8_K	66_R	1.885	0.98
476_V	485_A	1.875	0.98
117_E	120_Q	1.858	0.98
426_V	452_V	1.858	0.98
103_A	145_L	1.841	0.98
336_L	340_Q	1.830	0.98
338_A	496_R	1.829	0.98
177_S	218_D	1.813	0.98
452_V	458_T	1.812	0.98
8_K	64_T	1.807	0.98
26_G	220_E	1.795	0.98
402_V	431_A	1.787	0.98
166_I	195_H	1.767	0.98
59_K	640_D	1.763	0.98
37_V	196_T	1.756	0.98
126_Q	130_Q	1.733	0.97
204_P	208_A	1.731	0.97
7_L	54_L	1.681	0.97
423_V	430_P	1.675	0.97
593_L	597_T	1.668	0.97
68_A	164_Q	1.654	0.97
615_L	618_F	1.636	0.96
41_G	44_G	1.626	0.96
23_V	27_I	1.616	0.96
31_I	196_T	1.606	0.96
44_G	47_K	1.597	0.96
386_E	418_D	1.587	0.96
15_P	19_E	1.585	0.96
294_D	297_K	1.582	0.96
555_I	572_F	1.556	0.95
477_K	481_D	1.553	0.95
455_P	458_T	1.545	0.95
68_A	87_H	1.544	0.95
41_G	47_K	1.531	0.95
331_L	335_D	1.520	0.94
451_R	454_L	1.514	0.94
458_T	463_V	1.506	0.94
77_A	565_A	1.496	0.94
124_R	162_G	1.495	0.94
633_A	637_A	1.486	0.94
476_V	482_S	1.482	0.94
64_T	73_A	1.481	0.94
190_L	195_H	1.479	0.94
111_A	160_M	1.473	0.93
407_N	412_L	1.458	0.93
448_K	451_R	1.455	0.93
32_Y	35_E	1.434	0.92
22_E	26_G	1.430	0.92
610_S	613_A	1.429	0.92
53_I	65_Y	1.429	0.92
282_G	295_A	1.423	0.92
70_Q	75_L	1.423	0.92
45_S	137_R	1.422	0.92
120_Q	123_L	1.419	0.92
105_Q	108_E	1.419	0.92
41_G	46_G	1.414	0.92
54_L	65_Y	1.405	0.92
9_D	62_S	1.392	0.91
336_L	348_A	1.392	0.91
532_S	535_V	1.391	0.91
154_S	163_G	1.390	0.91
448_K	454_L	1.388	0.91
449_V	459_M	1.383	0.91
8_K	28_S	1.381	0.91
212_R	224_N	1.377	0.91
43_S	152_R	1.376	0.91
151_Q	157_R	1.374	0.91
304_I	510_V	1.366	0.90
463_V	469_L	1.358	0.90
409_R	413_F	1.357	0.90
184_M	206_V	1.355	0.90
34_G	191_R	1.349	0.90
10_I	53_I	1.347	0.90
384_F	389_T	1.344	0.90
551_R	554_E	1.340	0.90
300_V	521_L	1.339	0.90
490_T	500_K	1.338	0.90
586_L	590_L	1.335	0.89
399_A	404_L	1.332	0.89
572_F	632_P	1.327	0.89
354_Q	358_L	1.326	0.89
106_N	152_R	1.323	0.89
417_A	422_E	1.317	0.89
21_V	61_T	1.312	0.89
336_L	339_I	1.304	0.88
106_N	157_R	1.293	0.88
431_A	463_V	1.290	0.88
635_N	639_L	1.284	0.88
155_I	186_I	1.269	0.87
21_V	45_S	1.268	0.87
462_R	465_G	1.265	0.87
137_R	145_L	1.264	0.87
128_L	159_L	1.255	0.86
186_I	189_Q	1.255	0.86
564_R	567_D	1.252	0.86
185_A	188_H	1.250	0.86
16_A	19_E	1.249	0.86
16_A	21_V	1.247	0.86
454_L	466_Q	1.240	0.86
214_I	221_I	1.239	0.86
263_R	266_A	1.237	0.85
104_E	138_T	1.233	0.85
128_L	160_M	1.229	0.85
183_V	187_L	1.226	0.85
82_Q	86_E	1.223	0.85
107_V	125_A	1.223	0.85
13_S	45_S	1.210	0.84
423_V	432_R	1.209	0.84
412_L	424_I	1.207	0.84
102_T	139_E	1.204	0.84
126_Q	135_E	1.201	0.84
558_R	563_A	1.200	0.84
418_D	422_E	1.196	0.83
138_T	197_V	1.194	0.83
453_W	459_M	1.191	0.83
334_D	342_Q	1.189	0.83
331_L	336_L	1.187	0.83
536_G	539_G	1.186	0.83
383_T	438_E	1.184	0.83
542_N	545_L	1.181	0.83
231_V	234_T	1.180	0.83
43_S	50_L	1.180	0.83
71_D	74_T	1.177	0.82
33_A	164_Q	1.170	0.82
425_L	430_P	1.170	0.82
453_W	460_S	1.167	0.82
456_Y	459_M	1.162	0.82
276_M	280_I	1.159	0.81
215_E	222_V	1.158	0.81
452_V	459_M	1.157	0.81
543_I	629_G	1.152	0.81
232_N	585_A	1.151	0.81
9_D	375_D	1.150	0.81
461_G	464_M	1.149	0.81
324_D	327_Y	1.146	0.81
497_H	501_D	1.138	0.80
581_L	622_T	1.134	0.80
13_S	62_S	1.124	0.79
9_D	634_R	1.119	0.79
132_L	200_V	1.117	0.79
33_A	195_H	1.114	0.79
572_F	575_E	1.113	0.79
95_Y	149_Q	1.110	0.79
299_M	303_D	1.110	0.79
283_I	587_G	1.109	0.79
226_P	230_K	1.108	0.78
130_Q	138_T	1.104	0.78
23_V	128_L	1.102	0.78
168_A	641_P	1.097	0.78
551_R	575_E	1.096	0.78
487_Q	490_T	1.096	0.78
104_E	122_L	1.095	0.78
459_M	463_V	1.093	0.77
81_A	559_M	1.093	0.77
451_R	469_L	1.092	0.77
409_R	414_P	1.089	0.77
297_K	301_L	1.088	0.77
451_R	458_T	1.088	0.77
537_G	628_F	1.086	0.77
102_T	120_Q	1.086	0.77
102_T	140_Y	1.085	0.77
556_G	572_F	1.074	0.76
207_A	212_R	1.071	0.76
19_E	22_E	1.069	0.76
134_L	137_R	1.068	0.76
595_A	609_F	1.067	0.76
557_I	591_S	1.058	0.75
319_D	500_K	1.051	0.75
152_R	157_R	1.050	0.75
459_M	464_M	1.044	0.74
163_G	184_M	1.042	0.74
13_S	19_E	1.042	0.74
43_S	106_N	1.039	0.74
402_V	452_V	1.036	0.74
365_V	412_L	1.036	0.74
474_V	489_L	1.036	0.74
24_L	27_I	1.035	0.73
289_I	529_A	1.035	0.73
173_G	575_E	1.034	0.73
118_R	122_L	1.032	0.73
387_G	435_G	1.031	0.73
338_A	350_P	1.030	0.73
88_F	165_V	1.030	0.73
450_L	453_W	1.029	0.73
474_V	485_A	1.029	0.73
127_E	130_Q	1.027	0.73
406_S	410_R	1.027	0.73
37_V	214_I	1.025	0.73
458_T	462_R	1.024	0.73
28_S	220_E	1.023	0.73
460_S	464_M	1.019	0.72
449_V	461_G	1.010	0.72
84_R	92_F	1.008	0.71
509_G	513_T	1.005	0.71
400_Q	404_L	1.005	0.71
592_L	596_F	1.004	0.71
458_T	466_Q	1.002	0.71
67_V	72_V	1.002	0.71
149_Q	174_A	1.001	0.71
123_L	126_Q	1.001	0.71
146_S	170_E	0.999	0.71
146_S	169_D	0.999	0.71
55_G	632_P	0.998	0.71
148_G	202_H	0.994	0.70
146_S	202_H	0.989	0.70
92_F	157_R	0.989	0.70
148_G	169_D	0.988	0.70
148_G	170_E	0.988	0.70
120_Q	124_R	0.987	0.70
533_L	636_A	0.985	0.70
141_Y	144_Q	0.982	0.69
38_A	45_S	0.981	0.69
601_F	619_L	0.976	0.69
334_D	340_Q	0.975	0.69
486_E	490_T	0.975	0.69
510_V	638_R	0.974	0.69
446_S	449_V	0.974	0.69
390_F	401_V	0.974	0.69
633_A	636_A	0.974	0.69
426_V	431_A	0.973	0.69
338_A	342_Q	0.968	0.68
454_L	464_M	0.967	0.68
117_E	197_V	0.962	0.68
318_K	489_L	0.961	0.68
108_E	121_R	0.960	0.68
152_R	175_L	0.959	0.68
72_V	80_L	0.957	0.67
93_Q	148_G	0.955	0.67
118_R	592_L	0.955	0.67
40_V	213_V	0.953	0.67
52_N	96_H	0.952	0.67
93_Q	146_S	0.949	0.67
529_A	564_R	0.949	0.67
577_V	626_I	0.942	0.66
27_I	474_V	0.942	0.66
271_R	281_I	0.942	0.66
294_D	608_G	0.940	0.66
191_R	197_V	0.938	0.66
132_L	203_D	0.935	0.66
104_E	126_Q	0.927	0.65
409_R	412_L	0.926	0.65
295_A	532_S	0.925	0.65
188_H	211_E	0.925	0.65
131_R	182_E	0.923	0.65
340_Q	348_A	0.922	0.65
16_A	186_I	0.922	0.65
166_I	263_R	0.920	0.64
42_A	61_T	0.920	0.64
70_Q	74_T	0.919	0.64
47_K	93_Q	0.918	0.64
292_V	568_V	0.916	0.64
315_Y	591_S	0.915	0.64
46_G	49_T	0.914	0.64
583_G	625_G	0.914	0.64
532_S	645_L	0.914	0.64
170_E	202_H	0.913	0.64
169_D	202_H	0.913	0.64
387_G	403_V	0.913	0.64
230_K	234_T	0.910	0.64
368_S	371_G	0.908	0.63
327_Y	338_A	0.908	0.63
335_D	350_P	0.907	0.63
225_P	228_I	0.905	0.63
52_N	92_F	0.905	0.63
47_K	170_E	0.902	0.63
47_K	169_D	0.902	0.63
404_L	409_R	0.901	0.63
56_C	149_Q	0.899	0.63
336_L	469_L	0.898	0.62
282_G	550_E	0.896	0.62
7_L	75_L	0.894	0.62
21_V	25_K	0.892	0.62
132_L	156_A	0.888	0.62
418_D	424_I	0.887	0.62
5_L	31_I	0.887	0.62
498_G	501_D	0.880	0.61
418_D	421_G	0.878	0.61
148_G	172_T	0.876	0.61
111_A	154_S	0.873	0.60
369_A	372_V	0.873	0.60
487_Q	491_R	0.872	0.60
54_L	613_A	0.872	0.60
581_L	585_A	0.871	0.60
14_Y	23_V	0.871	0.60
12_R	49_T	0.871	0.60
224_N	227_A	0.870	0.60
212_R	219_G	0.869	0.60
385_S	437_A	0.868	0.60
93_Q	202_H	0.866	0.60
490_T	494_S	0.864	0.59
89_G	201_T	0.863	0.59
592_L	614_L	0.860	0.59
598_L	605_W	0.860	0.59
392_Q	420_V	0.858	0.59
189_Q	193_R	0.858	0.59
255_N	589_T	0.857	0.59
93_Q	170_E	0.857	0.59
93_Q	169_D	0.857	0.59
44_G	49_T	0.856	0.59
81_A	85_R	0.856	0.59
189_Q	589_T	0.855	0.59
91_I	200_V	0.854	0.59
168_A	575_E	0.853	0.58
35_E	212_R	0.852	0.58
114_A	559_M	0.852	0.58
92_F	151_Q	0.851	0.58
313_D	471_S	0.851	0.58
282_G	536_G	0.850	0.58
587_G	591_S	0.848	0.58
188_H	191_R	0.848	0.58
406_S	409_R	0.845	0.58
476_V	489_L	0.843	0.58
151_Q	175_L	0.843	0.58
37_V	212_R	0.841	0.57
122_L	126_Q	0.841	0.57
225_P	230_K	0.841	0.57
356_L	426_V	0.839	0.57
332_K	589_T	0.838	0.57
312_I	489_L	0.834	0.57
206_V	269_K	0.834	0.57
23_V	219_G	0.832	0.57
126_Q	245_S	0.831	0.56
38_A	207_A	0.829	0.56
420_V	424_I	0.829	0.56
608_G	614_L	0.828	0.56
95_Y	154_S	0.827	0.56
184_M	642_V	0.825	0.56
181_E	185_A	0.825	0.56
420_V	434_I	0.823	0.56
94_R	580_C	0.822	0.56
197_V	489_L	0.822	0.56
45_S	210_A	0.821	0.56
289_I	538_I	0.819	0.55
481_D	484_E	0.818	0.55
556_G	568_V	0.817	0.55
72_V	300_V	0.817	0.55
197_V	500_K	0.817	0.55
421_G	425_L	0.815	0.55
91_I	151_Q	0.813	0.55
457_S	468_W	0.813	0.55
46_G	93_Q	0.811	0.55
548_V	636_A	0.809	0.54
483_A	495_L	0.807	0.54
39_I	221_I	0.807	0.54
199_I	207_A	0.803	0.54
334_D	338_A	0.802	0.54
288_S	579_V	0.802	0.54
296_A	301_L	0.801	0.54
278_G	285_S	0.801	0.54
113_Y	620_C	0.800	0.54
142_P	174_A	0.800	0.54
136_D	139_E	0.799	0.54
46_G	169_D	0.798	0.53
46_G	170_E	0.798	0.53
453_W	464_M	0.797	0.53
628_F	632_P	0.797	0.53
57_L	212_R	0.795	0.53
157_R	200_V	0.795	0.53
483_A	486_E	0.795	0.53
8_K	220_E	0.794	0.53
103_A	137_R	0.794	0.53
204_P	213_V	0.793	0.53
356_L	359_R	0.793	0.53
55_G	90_F	0.791	0.53
331_L	338_A	0.790	0.53
51_M	639_L	0.789	0.53
92_F	556_G	0.789	0.53
41_G	49_T	0.788	0.53
344_W	350_P	0.788	0.53
294_D	298_Q	0.787	0.52
490_T	504_T	0.787	0.52
199_I	629_G	0.786	0.52
52_N	95_Y	0.785	0.52
286_V	529_A	0.785	0.52
456_Y	462_R	0.784	0.52
405_D	480_F	0.784	0.52
464_M	467_S	0.780	0.52
453_W	469_L	0.779	0.52
198_I	409_R	0.779	0.52
593_L	596_F	0.779	0.52
532_S	540_V	0.779	0.52
13_S	21_V	0.778	0.52
151_Q	154_S	0.777	0.51
20_Q	27_I	0.775	0.51
67_V	87_H	0.775	0.51
210_A	217_R	0.774	0.51
420_V	428_N	0.771	0.51
119_K	415_H	0.771	0.51
312_I	504_T	0.770	0.51
64_T	345_V	0.770	0.51
58_D	149_Q	0.770	0.51
289_I	309_T	0.769	0.51
292_V	624_T	0.765	0.50
177_S	204_P	0.764	0.50
459_M	466_Q	0.764	0.50
12_R	63_G	0.762	0.50
367_A	370_N	0.762	0.50
551_R	572_F	0.760	0.50
173_G	207_A	0.759	0.50
344_W	477_K	0.759	0.50
541_M	545_L	0.759	0.50
525_L	548_V	0.759	0.50
627_L	631_L	0.759	0.50
227_A	230_K	0.759	0.50
142_P	295_A	0.758	0.50
44_G	93_Q	0.757	0.50
272_T	275_T	0.756	0.50
20_Q	467_S	0.756	0.50
9_D	119_K	0.755	0.49
39_I	200_V	0.754	0.49
119_K	123_L	0.753	0.49
20_Q	139_E	0.753	0.49
566_S	570_Q	0.753	0.49
370_N	374_G	0.753	0.49
7_L	50_L	0.752	0.49
160_M	641_P	0.752	0.49
96_H	547_S	0.749	0.49
119_K	600_L	0.748	0.49
65_Y	88_F	0.748	0.49
556_G	560_A	0.748	0.49
459_M	468_W	0.747	0.49
449_V	455_P	0.746	0.49
282_G	285_S	0.746	0.49
548_V	632_P	0.746	0.49
12_R	58_D	0.745	0.49
96_H	154_S	0.745	0.49
68_A	638_R	0.744	0.48
352_V	464_M	0.744	0.48
624_T	642_V	0.744	0.48
603_P	606_E	0.744	0.48
44_G	169_D	0.743	0.48
44_G	170_E	0.743	0.48
448_K	458_T	0.742	0.48
452_V	469_L	0.742	0.48
189_Q	211_E	0.740	0.48
495_L	500_K	0.740	0.48
198_I	565_A	0.739	0.48
274_L	583_G	0.738	0.48
271_R	550_E	0.737	0.48
547_S	632_P	0.737	0.48
65_Y	83_L	0.737	0.48
295_A	550_E	0.737	0.48
37_V	144_Q	0.735	0.48
421_G	426_V	0.734	0.47
35_E	196_T	0.734	0.47
59_K	643_D	0.733	0.47
409_R	433_V	0.733	0.47
13_S	25_K	0.732	0.47
458_T	461_G	0.731	0.47
386_E	420_V	0.731	0.47
278_G	532_S	0.729	0.47
48_S	595_A	0.729	0.47
91_I	611_P	0.728	0.47
532_S	584_G	0.727	0.47
154_S	162_G	0.726	0.47
594_I	597_T	0.726	0.47
555_I	632_P	0.725	0.47
23_V	185_A	0.724	0.47
642_V	646_A	0.723	0.46
487_Q	619_L	0.722	0.46
145_L	568_V	0.721	0.46
369_A	502_F	0.720	0.46
302_A	306_S	0.718	0.46
98_L	191_R	0.716	0.46
489_L	492_L	0.716	0.46
388_N	415_H	0.715	0.46
162_G	400_Q	0.713	0.46
185_A	189_Q	0.711	0.45
199_I	261_A	0.711	0.45
278_G	539_G	0.710	0.45
273_L	586_L	0.708	0.45
38_A	89_G	0.708	0.45
535_V	550_E	0.708	0.45
261_A	272_T	0.707	0.45
325_P	328_Q	0.707	0.45
43_S	175_L	0.707	0.45
217_R	222_V	0.706	0.45
608_G	633_A	0.705	0.45
233_V	236_G	0.705	0.45
22_E	220_E	0.704	0.45
20_Q	422_E	0.704	0.45
346_A	378_N	0.704	0.45
334_D	339_I	0.704	0.45
302_A	512_K	0.703	0.45
405_D	437_A	0.703	0.45
234_T	534_V	0.702	0.45
38_A	201_T	0.701	0.44
52_N	157_R	0.696	0.44
43_S	157_R	0.695	0.44
584_G	646_A	0.694	0.44
216_I	498_G	0.694	0.44
95_Y	151_Q	0.693	0.44
279_I	285_S	0.691	0.44
55_G	641_P	0.691	0.44
132_L	183_V	0.691	0.44
244_V	589_T	0.690	0.43
230_K	566_S	0.690	0.43
295_A	584_G	0.690	0.43
274_L	282_G	0.690	0.43
439_E	454_L	0.689	0.43
41_G	93_Q	0.688	0.43
108_E	579_V	0.685	0.43
197_V	561_V	0.685	0.43
43_S	92_F	0.684	0.43
454_L	462_R	0.683	0.43
92_F	95_Y	0.681	0.43
601_F	616_L	0.680	0.43
598_L	607_I	0.680	0.43
149_Q	175_L	0.679	0.42
123_L	232_N	0.679	0.42
157_R	168_A	0.679	0.42
25_K	186_I	0.678	0.42
245_S	615_L	0.678	0.42
558_R	571_Q	0.678	0.42
401_V	404_L	0.677	0.42
50_L	113_Y	0.676	0.42
230_K	477_K	0.676	0.42
152_R	172_T	0.675	0.42
169_D	176_D	0.674	0.42
170_E	176_D	0.674	0.42
255_N	487_Q	0.673	0.42
41_G	169_D	0.673	0.42
41_G	170_E	0.673	0.42
36_M	96_H	0.672	0.42
32_Y	226_P	0.671	0.42
102_T	154_S	0.671	0.42
354_Q	638_R	0.668	0.41
114_A	557_I	0.667	0.41
426_V	429_M	0.667	0.41
9_D	243_T	0.667	0.41
63_G	157_R	0.667	0.41
548_V	556_G	0.666	0.41
314_V	607_I	0.666	0.41
55_G	567_D	0.666	0.41
550_E	556_G	0.665	0.41
565_A	637_A	0.665	0.41
168_A	173_G	0.665	0.41
206_V	261_A	0.665	0.41
453_W	458_T	0.664	0.41
556_G	641_P	0.663	0.41
95_Y	200_V	0.663	0.41
449_V	454_L	0.663	0.41
50_L	106_N	0.663	0.41
47_K	146_S	0.662	0.41
539_G	542_N	0.661	0.41
632_P	636_A	0.660	0.41
544_M	633_A	0.660	0.41
9_D	220_E	0.659	0.41
430_P	434_I	0.658	0.41
554_E	575_E	0.658	0.41
344_W	481_D	0.658	0.41
62_S	392_Q	0.658	0.41
333_Y	353_S	0.657	0.40
9_D	611_P	0.656	0.40
371_G	374_G	0.656	0.40
5_L	165_V	0.656	0.40
388_N	488_Q	0.655	0.40
392_Q	421_G	0.655	0.40
231_V	236_G	0.653	0.40
47_K	148_G	0.652	0.40
191_R	598_L	0.651	0.40
208_A	215_E	0.651	0.40
339_I	496_R	0.650	0.40
634_R	638_R	0.650	0.40
333_Y	348_A	0.649	0.40
121_R	124_R	0.647	0.40
12_R	56_C	0.647	0.40
220_E	360_Y	0.647	0.40
35_E	125_A	0.646	0.39
58_D	387_G	0.646	0.39
511_L	561_V	0.646	0.39
10_I	599_Q	0.645	0.39
355_N	358_L	0.645	0.39
339_I	342_Q	0.644	0.39
90_F	556_G	0.643	0.39
45_S	61_T	0.642	0.39
333_Y	340_Q	0.642	0.39
550_E	572_F	0.642	0.39
168_A	200_V	0.642	0.39
149_Q	168_A	0.639	0.39
55_G	167_L	0.639	0.39
484_E	488_Q	0.639	0.39
422_E	426_V	0.637	0.39
14_Y	100_H	0.636	0.39
120_Q	638_R	0.635	0.38
120_Q	341_K	0.634	0.38
458_T	465_G	0.634	0.38
502_F	524_F	0.634	0.38
601_F	604_G	0.633	0.38
90_F	168_A	0.631	0.38
407_N	410_R	0.631	0.38
419_V	424_I	0.630	0.38
216_I	560_A	0.630	0.38
331_L	334_D	0.630	0.38
605_W	619_L	0.630	0.38
591_S	602_L	0.630	0.38
334_D	337_I	0.629	0.38
550_E	555_I	0.628	0.38
21_V	582_V	0.627	0.38
406_S	438_E	0.626	0.38
11_R	28_S	0.626	0.38
31_I	37_V	0.626	0.38
282_G	548_V	0.626	0.38
132_L	167_L	0.625	0.38
384_F	616_L	0.625	0.38
216_I	222_V	0.625	0.38
448_K	453_W	0.623	0.37
131_R	341_K	0.623	0.37
574_I	578_L	0.623	0.37
66_R	71_D	0.623	0.37
587_G	632_P	0.623	0.37
83_L	88_F	0.622	0.37
161_N	282_G	0.622	0.37
104_E	139_E	0.622	0.37
474_V	513_T	0.622	0.37
92_F	173_G	0.621	0.37
164_Q	277_L	0.621	0.37
295_A	645_L	0.620	0.37
43_S	47_K	0.620	0.37
387_G	401_V	0.619	0.37
445_G	450_L	0.618	0.37
157_R	173_G	0.617	0.37
346_A	349_T	0.617	0.37
226_P	229_E	0.617	0.37
106_N	203_D	0.616	0.37
95_Y	167_L	0.616	0.37
102_T	108_E	0.615	0.37
402_V	408_T	0.615	0.37
295_A	572_F	0.614	0.37
584_G	629_G	0.613	0.37
13_S	23_V	0.612	0.36
28_S	59_K	0.611	0.36
139_E	589_T	0.611	0.36
184_M	199_I	0.610	0.36
587_G	629_G	0.609	0.36
43_S	46_G	0.609	0.36
55_G	142_P	0.608	0.36
346_A	373_S	0.607	0.36
113_Y	558_R	0.606	0.36
282_G	533_L	0.604	0.36
49_T	63_G	0.604	0.36
570_Q	620_C	0.603	0.36
87_H	164_Q	0.602	0.36
10_I	40_V	0.601	0.36
115_G	624_T	0.601	0.36
45_S	159_L	0.601	0.36
221_I	335_D	0.600	0.35
5_L	567_D	0.600	0.35
279_I	283_I	0.599	0.35
121_R	183_V	0.598	0.35
20_Q	361_N	0.598	0.35
558_R	625_G	0.597	0.35
302_A	305_R	0.596	0.35
175_L	200_V	0.596	0.35
161_N	629_G	0.596	0.35
161_N	584_G	0.595	0.35
226_P	231_V	0.594	0.35
94_R	98_L	0.594	0.35
101_L	377_F	0.594	0.35
178_H	181_E	0.593	0.35
33_A	68_A	0.593	0.35
52_N	556_G	0.593	0.35
95_Y	180_G	0.592	0.35
10_I	383_T	0.591	0.35
198_I	399_A	0.591	0.35
378_N	586_L	0.590	0.35
63_G	219_G	0.589	0.35
542_N	546_V	0.589	0.35
583_G	587_G	0.589	0.35
454_L	468_W	0.589	0.35
236_G	243_T	0.589	0.35
543_I	546_V	0.588	0.34
51_M	194_G	0.587	0.34
12_R	48_S	0.587	0.34
388_N	522_Q	0.586	0.34
538_I	579_V	0.586	0.34
236_G	337_I	0.585	0.34
535_V	639_L	0.585	0.34
132_L	186_I	0.584	0.34
147_G	201_T	0.584	0.34
476_V	479_G	0.583	0.34
184_M	188_H	0.582	0.34
508_D	513_T	0.582	0.34
32_Y	184_M	0.579	0.34
48_S	94_R	0.579	0.34
289_I	525_L	0.578	0.34
446_S	451_R	0.578	0.34
47_K	202_H	0.576	0.33
232_N	589_T	0.576	0.33
449_V	516_K	0.576	0.33
36_M	199_I	0.575	0.33
92_F	175_L	0.574	0.33
10_I	64_T	0.574	0.33
540_V	550_E	0.573	0.33
157_R	175_L	0.573	0.33
235_G	243_T	0.573	0.33
438_E	606_E	0.573	0.33
446_S	484_E	0.573	0.33
142_P	153_V	0.572	0.33
611_P	615_L	0.571	0.33
462_R	466_Q	0.570	0.33
53_I	61_T	0.570	0.33
142_P	550_E	0.569	0.33
555_I	560_A	0.569	0.33
271_R	282_G	0.568	0.33
11_R	25_K	0.567	0.33
518_T	524_F	0.567	0.33
25_K	38_A	0.567	0.33
594_I	598_L	0.567	0.33
331_L	471_S	0.567	0.33
124_R	127_E	0.567	0.33
110_P	161_N	0.567	0.33
203_D	521_L	0.566	0.33
354_Q	357_R	0.566	0.33
102_T	509_G	0.566	0.33
244_V	603_P	0.565	0.33
151_Q	168_A	0.565	0.33
194_G	639_L	0.565	0.33
58_D	157_R	0.564	0.32
64_T	117_E	0.564	0.32
564_R	610_S	0.564	0.32
532_S	548_V	0.563	0.32
362_N	365_V	0.563	0.32
584_G	587_G	0.562	0.32
84_R	212_R	0.562	0.32
213_V	472_I	0.562	0.32
282_G	633_A	0.561	0.32
387_G	629_G	0.560	0.32
67_V	407_N	0.560	0.32
577_V	622_T	0.560	0.32
405_D	433_V	0.559	0.32
149_Q	214_I	0.559	0.32
37_V	597_T	0.559	0.32
489_L	528_V	0.559	0.32
518_T	557_I	0.558	0.32
168_A	473_T	0.558	0.32
332_K	496_R	0.558	0.32
36_M	87_H	0.558	0.32
178_H	182_E	0.557	0.32
51_M	526_T	0.557	0.32
31_I	221_I	0.557	0.32
46_G	146_S	0.556	0.32
314_V	522_Q	0.556	0.32
38_A	212_R	0.555	0.32
584_G	636_A	0.555	0.32
16_A	45_S	0.555	0.32
617_A	625_G	0.554	0.32
43_S	172_T	0.553	0.32
359_R	364_D	0.553	0.32
585_A	596_F	0.553	0.32
538_I	563_A	0.551	0.31
151_Q	174_A	0.551	0.31
181_E	297_K	0.551	0.31
66_R	222_V	0.551	0.31
212_R	587_G	0.550	0.31
184_M	195_H	0.550	0.31
532_S	550_E	0.549	0.31
226_P	596_F	0.549	0.31
106_N	151_Q	0.548	0.31
46_G	148_G	0.547	0.31
437_A	453_W	0.547	0.31
563_A	571_Q	0.546	0.31
290_V	525_L	0.546	0.31
206_V	209_Q	0.546	0.31
261_A	282_G	0.545	0.31
89_G	641_P	0.544	0.31
87_H	165_V	0.544	0.31
260_M	264_A	0.543	0.31
548_V	555_I	0.542	0.31
65_Y	72_V	0.542	0.31
151_Q	575_E	0.541	0.31
422_E	425_L	0.540	0.31
304_I	509_G	0.540	0.31
26_G	443_M	0.538	0.30
511_L	514_V	0.537	0.30
215_E	225_P	0.536	0.30
271_R	283_I	0.535	0.30
387_G	390_F	0.535	0.30
274_L	287_V	0.534	0.30
211_E	229_E	0.534	0.30
291_V	305_R	0.533	0.30
371_G	459_M	0.533	0.30
221_I	231_V	0.533	0.30
34_G	194_G	0.533	0.30
236_G	623_V	0.533	0.30
97_L	150_Q	0.532	0.30
132_L	174_A	0.531	0.30
191_R	292_V	0.531	0.30
56_C	94_R	0.531	0.30
539_G	550_E	0.531	0.30
129_L	156_A	0.531	0.30
229_E	235_G	0.530	0.30
486_E	506_N	0.530	0.30
173_G	218_D	0.529	0.30
38_A	217_R	0.529	0.30
7_L	582_V	0.529	0.30
385_S	438_E	0.528	0.30
13_S	642_V	0.528	0.30
440_K	489_L	0.527	0.30
528_V	542_N	0.527	0.30
304_I	476_V	0.527	0.30
360_Y	422_E	0.526	0.29
319_D	622_T	0.526	0.29
19_E	426_V	0.525	0.29
146_S	172_T	0.525	0.29
409_R	415_H	0.525	0.29
210_A	213_V	0.524	0.29
154_S	609_F	0.523	0.29
106_N	175_L	0.523	0.29
421_G	424_I	0.523	0.29
81_A	196_T	0.522	0.29
58_D	92_F	0.521	0.29
166_I	579_V	0.521	0.29
10_I	512_K	0.521	0.29
574_I	625_G	0.521	0.29
354_Q	464_M	0.521	0.29
24_L	554_E	0.521	0.29
107_V	160_M	0.520	0.29
155_I	171_P	0.519	0.29
173_G	200_V	0.519	0.29
110_P	160_M	0.519	0.29
484_E	487_Q	0.518	0.29
299_M	606_E	0.518	0.29
203_D	206_V	0.518	0.29
413_F	423_V	0.517	0.29
541_M	571_Q	0.517	0.29
457_S	619_L	0.516	0.29
386_E	404_L	0.516	0.29
453_W	457_S	0.516	0.29
584_G	621_S	0.516	0.29
60_A	80_L	0.515	0.29
35_E	45_S	0.515	0.29
336_L	345_V	0.515	0.29
551_R	587_G	0.515	0.29
428_N	638_R	0.514	0.29
164_Q	195_H	0.514	0.29
424_I	618_F	0.514	0.29
48_S	640_D	0.514	0.29
325_P	471_S	0.514	0.29
328_Q	341_K	0.513	0.28
542_N	549_T	0.512	0.28
282_G	572_F	0.512	0.28
384_F	388_N	0.511	0.28
92_F	563_A	0.511	0.28
54_L	60_A	0.511	0.28
208_A	619_L	0.511	0.28
201_T	636_A	0.510	0.28
346_A	475_R	0.510	0.28
546_V	641_P	0.510	0.28
402_V	405_D	0.510	0.28
113_Y	536_G	0.510	0.28
341_K	457_S	0.510	0.28
181_E	205_Q	0.509	0.28
568_V	639_L	0.509	0.28
235_G	585_A	0.508	0.28
50_L	152_R	0.508	0.28
215_E	489_L	0.507	0.28
289_I	514_V	0.507	0.28
235_G	246_G	0.507	0.28
76_D	141_Y	0.507	0.28
110_P	179_S	0.507	0.28
201_T	207_A	0.506	0.28
37_V	55_G	0.506	0.28
411_Q	415_H	0.506	0.28
112_V	260_M	0.505	0.28
612_L	615_L	0.503	0.28
261_A	275_T	0.503	0.28
303_D	307_I	0.502	0.28
44_G	146_S	0.502	0.28
159_L	190_L	0.502	0.28
557_I	624_T	0.502	0.28
137_R	183_V	0.502	0.28
163_G	540_V	0.501	0.28
257_A	579_V	0.501	0.28
130_Q	467_S	0.501	0.28
149_Q	166_I	0.500	0.27
190_L	559_M	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tuiC	2	0.5247	100	0.548	Contact Map
2pcjA	2	0.3441	100	0.562	Contact Map
3tifA	4	0.3503	100	0.564	Contact Map
4u00A	1	0.3688	100	0.566	Contact Map
2oljA	2	0.3704	100	0.567	Contact Map
4yerA	2	0.4367	100	0.569	Contact Map
4huqB	1	0.4213	100	0.57	Contact Map
1b0uA	2	0.3781	100	0.571	Contact Map
4ymuJ	2	0.3673	100	0.573	Contact Map
1g291	4	0.5401	100	0.574	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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