GREMLIN Database
MACB - Macrolide export ATP-binding/permease protein MacB
UniProt: P75831 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13695
Length: 648 (627)
Sequences: 1394 (1031)
Seq/√Len: 41.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_E30_D8.4421.00
38_A210_A8.2221.00
9_D26_G7.0921.00
130_Q135_E6.6281.00
131_R189_Q6.3471.00
7_L10_I6.3191.00
64_T71_D6.3071.00
25_K220_E6.1611.00
9_D28_S5.7691.00
123_L127_E5.2551.00
127_E131_R5.1021.00
11_R26_G4.9041.00
22_E25_K4.7531.00
137_R140_Y4.6061.00
126_Q138_T4.3871.00
31_I198_I4.0631.00
8_K30_D3.7421.00
640_D643_D3.7321.00
454_L458_T3.6631.00
76_D79_A3.6611.00
454_L459_M3.3871.00
183_V186_I3.2791.00
102_T105_Q3.1121.00
454_L469_L3.0991.00
177_S217_R3.0761.00
208_A213_V2.9771.00
162_G195_H2.9751.00
567_D570_Q2.9271.00
191_R211_E2.9151.00
404_L424_I2.7921.00
11_R22_E2.7431.00
388_N434_I2.7411.00
5_L67_V2.6851.00
107_V129_L2.6251.00
40_V204_P2.6101.00
13_S22_E2.6031.00
454_L463_V2.6021.00
13_S61_T2.5381.00
155_I183_V2.4841.00
615_L619_L2.4581.00
335_D338_A2.4471.00
108_E122_L2.4231.00
131_R193_R2.3941.00
216_I221_I2.3161.00
163_G195_H2.3061.00
13_S20_Q2.2831.00
6_E66_R2.2751.00
70_Q79_A2.2401.00
478_E481_D2.2361.00
104_E125_A2.2211.00
105_Q263_R2.1951.00
95_Y174_A2.1951.00
15_P20_Q2.1841.00
215_E223_R2.1610.99
135_E138_T2.1100.99
458_T469_L2.1020.99
419_V422_E2.0970.99
188_H209_Q2.0210.99
204_P215_E2.0110.99
11_R62_S2.0070.99
140_Y144_Q1.9590.99
585_A589_T1.9290.99
344_W485_A1.8990.99
8_K66_R1.8850.98
476_V485_A1.8750.98
117_E120_Q1.8580.98
426_V452_V1.8580.98
103_A145_L1.8410.98
336_L340_Q1.8300.98
338_A496_R1.8290.98
177_S218_D1.8130.98
452_V458_T1.8120.98
8_K64_T1.8070.98
26_G220_E1.7950.98
402_V431_A1.7870.98
166_I195_H1.7670.98
59_K640_D1.7630.98
37_V196_T1.7560.98
126_Q130_Q1.7330.97
204_P208_A1.7310.97
7_L54_L1.6810.97
423_V430_P1.6750.97
593_L597_T1.6680.97
68_A164_Q1.6540.97
615_L618_F1.6360.96
41_G44_G1.6260.96
23_V27_I1.6160.96
31_I196_T1.6060.96
44_G47_K1.5970.96
386_E418_D1.5870.96
15_P19_E1.5850.96
294_D297_K1.5820.96
555_I572_F1.5560.95
477_K481_D1.5530.95
455_P458_T1.5450.95
68_A87_H1.5440.95
41_G47_K1.5310.95
331_L335_D1.5200.94
451_R454_L1.5140.94
458_T463_V1.5060.94
77_A565_A1.4960.94
124_R162_G1.4950.94
633_A637_A1.4860.94
476_V482_S1.4820.94
64_T73_A1.4810.94
190_L195_H1.4790.94
111_A160_M1.4730.93
407_N412_L1.4580.93
448_K451_R1.4550.93
32_Y35_E1.4340.92
22_E26_G1.4300.92
610_S613_A1.4290.92
53_I65_Y1.4290.92
282_G295_A1.4230.92
70_Q75_L1.4230.92
45_S137_R1.4220.92
120_Q123_L1.4190.92
105_Q108_E1.4190.92
41_G46_G1.4140.92
54_L65_Y1.4050.92
9_D62_S1.3920.91
336_L348_A1.3920.91
532_S535_V1.3910.91
154_S163_G1.3900.91
448_K454_L1.3880.91
449_V459_M1.3830.91
8_K28_S1.3810.91
212_R224_N1.3770.91
43_S152_R1.3760.91
151_Q157_R1.3740.91
304_I510_V1.3660.90
463_V469_L1.3580.90
409_R413_F1.3570.90
184_M206_V1.3550.90
34_G191_R1.3490.90
10_I53_I1.3470.90
384_F389_T1.3440.90
551_R554_E1.3400.90
300_V521_L1.3390.90
490_T500_K1.3380.90
586_L590_L1.3350.89
399_A404_L1.3320.89
572_F632_P1.3270.89
354_Q358_L1.3260.89
106_N152_R1.3230.89
417_A422_E1.3170.89
21_V61_T1.3120.89
336_L339_I1.3040.88
106_N157_R1.2930.88
431_A463_V1.2900.88
635_N639_L1.2840.88
155_I186_I1.2690.87
21_V45_S1.2680.87
462_R465_G1.2650.87
137_R145_L1.2640.87
128_L159_L1.2550.86
186_I189_Q1.2550.86
564_R567_D1.2520.86
185_A188_H1.2500.86
16_A19_E1.2490.86
16_A21_V1.2470.86
454_L466_Q1.2400.86
214_I221_I1.2390.86
263_R266_A1.2370.85
104_E138_T1.2330.85
128_L160_M1.2290.85
183_V187_L1.2260.85
82_Q86_E1.2230.85
107_V125_A1.2230.85
13_S45_S1.2100.84
423_V432_R1.2090.84
412_L424_I1.2070.84
102_T139_E1.2040.84
126_Q135_E1.2010.84
558_R563_A1.2000.84
418_D422_E1.1960.83
138_T197_V1.1940.83
453_W459_M1.1910.83
334_D342_Q1.1890.83
331_L336_L1.1870.83
536_G539_G1.1860.83
383_T438_E1.1840.83
542_N545_L1.1810.83
231_V234_T1.1800.83
43_S50_L1.1800.83
71_D74_T1.1770.82
33_A164_Q1.1700.82
425_L430_P1.1700.82
453_W460_S1.1670.82
456_Y459_M1.1620.82
276_M280_I1.1590.81
215_E222_V1.1580.81
452_V459_M1.1570.81
543_I629_G1.1520.81
232_N585_A1.1510.81
9_D375_D1.1500.81
461_G464_M1.1490.81
324_D327_Y1.1460.81
497_H501_D1.1380.80
581_L622_T1.1340.80
13_S62_S1.1240.79
9_D634_R1.1190.79
132_L200_V1.1170.79
33_A195_H1.1140.79
572_F575_E1.1130.79
95_Y149_Q1.1100.79
299_M303_D1.1100.79
283_I587_G1.1090.79
226_P230_K1.1080.78
130_Q138_T1.1040.78
23_V128_L1.1020.78
168_A641_P1.0970.78
551_R575_E1.0960.78
487_Q490_T1.0960.78
104_E122_L1.0950.78
459_M463_V1.0930.77
81_A559_M1.0930.77
451_R469_L1.0920.77
409_R414_P1.0890.77
297_K301_L1.0880.77
451_R458_T1.0880.77
537_G628_F1.0860.77
102_T120_Q1.0860.77
102_T140_Y1.0850.77
556_G572_F1.0740.76
207_A212_R1.0710.76
19_E22_E1.0690.76
134_L137_R1.0680.76
595_A609_F1.0670.76
557_I591_S1.0580.75
319_D500_K1.0510.75
152_R157_R1.0500.75
459_M464_M1.0440.74
163_G184_M1.0420.74
13_S19_E1.0420.74
43_S106_N1.0390.74
402_V452_V1.0360.74
365_V412_L1.0360.74
474_V489_L1.0360.74
24_L27_I1.0350.73
289_I529_A1.0350.73
173_G575_E1.0340.73
118_R122_L1.0320.73
387_G435_G1.0310.73
338_A350_P1.0300.73
88_F165_V1.0300.73
450_L453_W1.0290.73
474_V485_A1.0290.73
127_E130_Q1.0270.73
406_S410_R1.0270.73
37_V214_I1.0250.73
458_T462_R1.0240.73
28_S220_E1.0230.73
460_S464_M1.0190.72
449_V461_G1.0100.72
84_R92_F1.0080.71
509_G513_T1.0050.71
400_Q404_L1.0050.71
592_L596_F1.0040.71
458_T466_Q1.0020.71
67_V72_V1.0020.71
149_Q174_A1.0010.71
123_L126_Q1.0010.71
146_S170_E0.9990.71
146_S169_D0.9990.71
55_G632_P0.9980.71
148_G202_H0.9940.70
146_S202_H0.9890.70
92_F157_R0.9890.70
148_G169_D0.9880.70
148_G170_E0.9880.70
120_Q124_R0.9870.70
533_L636_A0.9850.70
141_Y144_Q0.9820.69
38_A45_S0.9810.69
601_F619_L0.9760.69
334_D340_Q0.9750.69
486_E490_T0.9750.69
510_V638_R0.9740.69
446_S449_V0.9740.69
390_F401_V0.9740.69
633_A636_A0.9740.69
426_V431_A0.9730.69
338_A342_Q0.9680.68
454_L464_M0.9670.68
117_E197_V0.9620.68
318_K489_L0.9610.68
108_E121_R0.9600.68
152_R175_L0.9590.68
72_V80_L0.9570.67
93_Q148_G0.9550.67
118_R592_L0.9550.67
40_V213_V0.9530.67
52_N96_H0.9520.67
93_Q146_S0.9490.67
529_A564_R0.9490.67
577_V626_I0.9420.66
27_I474_V0.9420.66
271_R281_I0.9420.66
294_D608_G0.9400.66
191_R197_V0.9380.66
132_L203_D0.9350.66
104_E126_Q0.9270.65
409_R412_L0.9260.65
295_A532_S0.9250.65
188_H211_E0.9250.65
131_R182_E0.9230.65
340_Q348_A0.9220.65
16_A186_I0.9220.65
166_I263_R0.9200.64
42_A61_T0.9200.64
70_Q74_T0.9190.64
47_K93_Q0.9180.64
292_V568_V0.9160.64
315_Y591_S0.9150.64
46_G49_T0.9140.64
583_G625_G0.9140.64
532_S645_L0.9140.64
170_E202_H0.9130.64
169_D202_H0.9130.64
387_G403_V0.9130.64
230_K234_T0.9100.64
368_S371_G0.9080.63
327_Y338_A0.9080.63
335_D350_P0.9070.63
225_P228_I0.9050.63
52_N92_F0.9050.63
47_K170_E0.9020.63
47_K169_D0.9020.63
404_L409_R0.9010.63
56_C149_Q0.8990.63
336_L469_L0.8980.62
282_G550_E0.8960.62
7_L75_L0.8940.62
21_V25_K0.8920.62
132_L156_A0.8880.62
418_D424_I0.8870.62
5_L31_I0.8870.62
498_G501_D0.8800.61
418_D421_G0.8780.61
148_G172_T0.8760.61
111_A154_S0.8730.60
369_A372_V0.8730.60
487_Q491_R0.8720.60
54_L613_A0.8720.60
581_L585_A0.8710.60
14_Y23_V0.8710.60
12_R49_T0.8710.60
224_N227_A0.8700.60
212_R219_G0.8690.60
385_S437_A0.8680.60
93_Q202_H0.8660.60
490_T494_S0.8640.59
89_G201_T0.8630.59
592_L614_L0.8600.59
598_L605_W0.8600.59
392_Q420_V0.8580.59
189_Q193_R0.8580.59
255_N589_T0.8570.59
93_Q170_E0.8570.59
93_Q169_D0.8570.59
44_G49_T0.8560.59
81_A85_R0.8560.59
189_Q589_T0.8550.59
91_I200_V0.8540.59
168_A575_E0.8530.58
35_E212_R0.8520.58
114_A559_M0.8520.58
92_F151_Q0.8510.58
313_D471_S0.8510.58
282_G536_G0.8500.58
587_G591_S0.8480.58
188_H191_R0.8480.58
406_S409_R0.8450.58
476_V489_L0.8430.58
151_Q175_L0.8430.58
37_V212_R0.8410.57
122_L126_Q0.8410.57
225_P230_K0.8410.57
356_L426_V0.8390.57
332_K589_T0.8380.57
312_I489_L0.8340.57
206_V269_K0.8340.57
23_V219_G0.8320.57
126_Q245_S0.8310.56
38_A207_A0.8290.56
420_V424_I0.8290.56
608_G614_L0.8280.56
95_Y154_S0.8270.56
184_M642_V0.8250.56
181_E185_A0.8250.56
420_V434_I0.8230.56
94_R580_C0.8220.56
197_V489_L0.8220.56
45_S210_A0.8210.56
289_I538_I0.8190.55
481_D484_E0.8180.55
556_G568_V0.8170.55
72_V300_V0.8170.55
197_V500_K0.8170.55
421_G425_L0.8150.55
91_I151_Q0.8130.55
457_S468_W0.8130.55
46_G93_Q0.8110.55
548_V636_A0.8090.54
483_A495_L0.8070.54
39_I221_I0.8070.54
199_I207_A0.8030.54
334_D338_A0.8020.54
288_S579_V0.8020.54
296_A301_L0.8010.54
278_G285_S0.8010.54
113_Y620_C0.8000.54
142_P174_A0.8000.54
136_D139_E0.7990.54
46_G169_D0.7980.53
46_G170_E0.7980.53
453_W464_M0.7970.53
628_F632_P0.7970.53
57_L212_R0.7950.53
157_R200_V0.7950.53
483_A486_E0.7950.53
8_K220_E0.7940.53
103_A137_R0.7940.53
204_P213_V0.7930.53
356_L359_R0.7930.53
55_G90_F0.7910.53
331_L338_A0.7900.53
51_M639_L0.7890.53
92_F556_G0.7890.53
41_G49_T0.7880.53
344_W350_P0.7880.53
294_D298_Q0.7870.52
490_T504_T0.7870.52
199_I629_G0.7860.52
52_N95_Y0.7850.52
286_V529_A0.7850.52
456_Y462_R0.7840.52
405_D480_F0.7840.52
464_M467_S0.7800.52
453_W469_L0.7790.52
198_I409_R0.7790.52
593_L596_F0.7790.52
532_S540_V0.7790.52
13_S21_V0.7780.52
151_Q154_S0.7770.51
20_Q27_I0.7750.51
67_V87_H0.7750.51
210_A217_R0.7740.51
420_V428_N0.7710.51
119_K415_H0.7710.51
312_I504_T0.7700.51
64_T345_V0.7700.51
58_D149_Q0.7700.51
289_I309_T0.7690.51
292_V624_T0.7650.50
177_S204_P0.7640.50
459_M466_Q0.7640.50
12_R63_G0.7620.50
367_A370_N0.7620.50
551_R572_F0.7600.50
173_G207_A0.7590.50
344_W477_K0.7590.50
541_M545_L0.7590.50
525_L548_V0.7590.50
627_L631_L0.7590.50
227_A230_K0.7590.50
142_P295_A0.7580.50
44_G93_Q0.7570.50
272_T275_T0.7560.50
20_Q467_S0.7560.50
9_D119_K0.7550.49
39_I200_V0.7540.49
119_K123_L0.7530.49
20_Q139_E0.7530.49
566_S570_Q0.7530.49
370_N374_G0.7530.49
7_L50_L0.7520.49
160_M641_P0.7520.49
96_H547_S0.7490.49
119_K600_L0.7480.49
65_Y88_F0.7480.49
556_G560_A0.7480.49
459_M468_W0.7470.49
449_V455_P0.7460.49
282_G285_S0.7460.49
548_V632_P0.7460.49
12_R58_D0.7450.49
96_H154_S0.7450.49
68_A638_R0.7440.48
352_V464_M0.7440.48
624_T642_V0.7440.48
603_P606_E0.7440.48
44_G169_D0.7430.48
44_G170_E0.7430.48
448_K458_T0.7420.48
452_V469_L0.7420.48
189_Q211_E0.7400.48
495_L500_K0.7400.48
198_I565_A0.7390.48
274_L583_G0.7380.48
271_R550_E0.7370.48
547_S632_P0.7370.48
65_Y83_L0.7370.48
295_A550_E0.7370.48
37_V144_Q0.7350.48
421_G426_V0.7340.47
35_E196_T0.7340.47
59_K643_D0.7330.47
409_R433_V0.7330.47
13_S25_K0.7320.47
458_T461_G0.7310.47
386_E420_V0.7310.47
278_G532_S0.7290.47
48_S595_A0.7290.47
91_I611_P0.7280.47
532_S584_G0.7270.47
154_S162_G0.7260.47
594_I597_T0.7260.47
555_I632_P0.7250.47
23_V185_A0.7240.47
642_V646_A0.7230.46
487_Q619_L0.7220.46
145_L568_V0.7210.46
369_A502_F0.7200.46
302_A306_S0.7180.46
98_L191_R0.7160.46
489_L492_L0.7160.46
388_N415_H0.7150.46
162_G400_Q0.7130.46
185_A189_Q0.7110.45
199_I261_A0.7110.45
278_G539_G0.7100.45
273_L586_L0.7080.45
38_A89_G0.7080.45
535_V550_E0.7080.45
261_A272_T0.7070.45
325_P328_Q0.7070.45
43_S175_L0.7070.45
217_R222_V0.7060.45
608_G633_A0.7050.45
233_V236_G0.7050.45
22_E220_E0.7040.45
20_Q422_E0.7040.45
346_A378_N0.7040.45
334_D339_I0.7040.45
302_A512_K0.7030.45
405_D437_A0.7030.45
234_T534_V0.7020.45
38_A201_T0.7010.44
52_N157_R0.6960.44
43_S157_R0.6950.44
584_G646_A0.6940.44
216_I498_G0.6940.44
95_Y151_Q0.6930.44
279_I285_S0.6910.44
55_G641_P0.6910.44
132_L183_V0.6910.44
244_V589_T0.6900.43
230_K566_S0.6900.43
295_A584_G0.6900.43
274_L282_G0.6900.43
439_E454_L0.6890.43
41_G93_Q0.6880.43
108_E579_V0.6850.43
197_V561_V0.6850.43
43_S92_F0.6840.43
454_L462_R0.6830.43
92_F95_Y0.6810.43
601_F616_L0.6800.43
598_L607_I0.6800.43
149_Q175_L0.6790.42
123_L232_N0.6790.42
157_R168_A0.6790.42
25_K186_I0.6780.42
245_S615_L0.6780.42
558_R571_Q0.6780.42
401_V404_L0.6770.42
50_L113_Y0.6760.42
230_K477_K0.6760.42
152_R172_T0.6750.42
169_D176_D0.6740.42
170_E176_D0.6740.42
255_N487_Q0.6730.42
41_G169_D0.6730.42
41_G170_E0.6730.42
36_M96_H0.6720.42
32_Y226_P0.6710.42
102_T154_S0.6710.42
354_Q638_R0.6680.41
114_A557_I0.6670.41
426_V429_M0.6670.41
9_D243_T0.6670.41
63_G157_R0.6670.41
548_V556_G0.6660.41
314_V607_I0.6660.41
55_G567_D0.6660.41
550_E556_G0.6650.41
565_A637_A0.6650.41
168_A173_G0.6650.41
206_V261_A0.6650.41
453_W458_T0.6640.41
556_G641_P0.6630.41
95_Y200_V0.6630.41
449_V454_L0.6630.41
50_L106_N0.6630.41
47_K146_S0.6620.41
539_G542_N0.6610.41
632_P636_A0.6600.41
544_M633_A0.6600.41
9_D220_E0.6590.41
430_P434_I0.6580.41
554_E575_E0.6580.41
344_W481_D0.6580.41
62_S392_Q0.6580.41
333_Y353_S0.6570.40
9_D611_P0.6560.40
371_G374_G0.6560.40
5_L165_V0.6560.40
388_N488_Q0.6550.40
392_Q421_G0.6550.40
231_V236_G0.6530.40
47_K148_G0.6520.40
191_R598_L0.6510.40
208_A215_E0.6510.40
339_I496_R0.6500.40
634_R638_R0.6500.40
333_Y348_A0.6490.40
121_R124_R0.6470.40
12_R56_C0.6470.40
220_E360_Y0.6470.40
35_E125_A0.6460.39
58_D387_G0.6460.39
511_L561_V0.6460.39
10_I599_Q0.6450.39
355_N358_L0.6450.39
339_I342_Q0.6440.39
90_F556_G0.6430.39
45_S61_T0.6420.39
333_Y340_Q0.6420.39
550_E572_F0.6420.39
168_A200_V0.6420.39
149_Q168_A0.6390.39
55_G167_L0.6390.39
484_E488_Q0.6390.39
422_E426_V0.6370.39
14_Y100_H0.6360.39
120_Q638_R0.6350.38
120_Q341_K0.6340.38
458_T465_G0.6340.38
502_F524_F0.6340.38
601_F604_G0.6330.38
90_F168_A0.6310.38
407_N410_R0.6310.38
419_V424_I0.6300.38
216_I560_A0.6300.38
331_L334_D0.6300.38
605_W619_L0.6300.38
591_S602_L0.6300.38
334_D337_I0.6290.38
550_E555_I0.6280.38
21_V582_V0.6270.38
406_S438_E0.6260.38
11_R28_S0.6260.38
31_I37_V0.6260.38
282_G548_V0.6260.38
132_L167_L0.6250.38
384_F616_L0.6250.38
216_I222_V0.6250.38
448_K453_W0.6230.37
131_R341_K0.6230.37
574_I578_L0.6230.37
66_R71_D0.6230.37
587_G632_P0.6230.37
83_L88_F0.6220.37
161_N282_G0.6220.37
104_E139_E0.6220.37
474_V513_T0.6220.37
92_F173_G0.6210.37
164_Q277_L0.6210.37
295_A645_L0.6200.37
43_S47_K0.6200.37
387_G401_V0.6190.37
445_G450_L0.6180.37
157_R173_G0.6170.37
346_A349_T0.6170.37
226_P229_E0.6170.37
106_N203_D0.6160.37
95_Y167_L0.6160.37
102_T108_E0.6150.37
402_V408_T0.6150.37
295_A572_F0.6140.37
584_G629_G0.6130.37
13_S23_V0.6120.36
28_S59_K0.6110.36
139_E589_T0.6110.36
184_M199_I0.6100.36
587_G629_G0.6090.36
43_S46_G0.6090.36
55_G142_P0.6080.36
346_A373_S0.6070.36
113_Y558_R0.6060.36
282_G533_L0.6040.36
49_T63_G0.6040.36
570_Q620_C0.6030.36
87_H164_Q0.6020.36
10_I40_V0.6010.36
115_G624_T0.6010.36
45_S159_L0.6010.36
221_I335_D0.6000.35
5_L567_D0.6000.35
279_I283_I0.5990.35
121_R183_V0.5980.35
20_Q361_N0.5980.35
558_R625_G0.5970.35
302_A305_R0.5960.35
175_L200_V0.5960.35
161_N629_G0.5960.35
161_N584_G0.5950.35
226_P231_V0.5940.35
94_R98_L0.5940.35
101_L377_F0.5940.35
178_H181_E0.5930.35
33_A68_A0.5930.35
52_N556_G0.5930.35
95_Y180_G0.5920.35
10_I383_T0.5910.35
198_I399_A0.5910.35
378_N586_L0.5900.35
63_G219_G0.5890.35
542_N546_V0.5890.35
583_G587_G0.5890.35
454_L468_W0.5890.35
236_G243_T0.5890.35
543_I546_V0.5880.34
51_M194_G0.5870.34
12_R48_S0.5870.34
388_N522_Q0.5860.34
538_I579_V0.5860.34
236_G337_I0.5850.34
535_V639_L0.5850.34
132_L186_I0.5840.34
147_G201_T0.5840.34
476_V479_G0.5830.34
184_M188_H0.5820.34
508_D513_T0.5820.34
32_Y184_M0.5790.34
48_S94_R0.5790.34
289_I525_L0.5780.34
446_S451_R0.5780.34
47_K202_H0.5760.33
232_N589_T0.5760.33
449_V516_K0.5760.33
36_M199_I0.5750.33
92_F175_L0.5740.33
10_I64_T0.5740.33
540_V550_E0.5730.33
157_R175_L0.5730.33
235_G243_T0.5730.33
438_E606_E0.5730.33
446_S484_E0.5730.33
142_P153_V0.5720.33
611_P615_L0.5710.33
462_R466_Q0.5700.33
53_I61_T0.5700.33
142_P550_E0.5690.33
555_I560_A0.5690.33
271_R282_G0.5680.33
11_R25_K0.5670.33
518_T524_F0.5670.33
25_K38_A0.5670.33
594_I598_L0.5670.33
331_L471_S0.5670.33
124_R127_E0.5670.33
110_P161_N0.5670.33
203_D521_L0.5660.33
354_Q357_R0.5660.33
102_T509_G0.5660.33
244_V603_P0.5650.33
151_Q168_A0.5650.33
194_G639_L0.5650.33
58_D157_R0.5640.32
64_T117_E0.5640.32
564_R610_S0.5640.32
532_S548_V0.5630.32
362_N365_V0.5630.32
584_G587_G0.5620.32
84_R212_R0.5620.32
213_V472_I0.5620.32
282_G633_A0.5610.32
387_G629_G0.5600.32
67_V407_N0.5600.32
577_V622_T0.5600.32
405_D433_V0.5590.32
149_Q214_I0.5590.32
37_V597_T0.5590.32
489_L528_V0.5590.32
518_T557_I0.5580.32
168_A473_T0.5580.32
332_K496_R0.5580.32
36_M87_H0.5580.32
178_H182_E0.5570.32
51_M526_T0.5570.32
31_I221_I0.5570.32
46_G146_S0.5560.32
314_V522_Q0.5560.32
38_A212_R0.5550.32
584_G636_A0.5550.32
16_A45_S0.5550.32
617_A625_G0.5540.32
43_S172_T0.5530.32
359_R364_D0.5530.32
585_A596_F0.5530.32
538_I563_A0.5510.31
151_Q174_A0.5510.31
181_E297_K0.5510.31
66_R222_V0.5510.31
212_R587_G0.5500.31
184_M195_H0.5500.31
532_S550_E0.5490.31
226_P596_F0.5490.31
106_N151_Q0.5480.31
46_G148_G0.5470.31
437_A453_W0.5470.31
563_A571_Q0.5460.31
290_V525_L0.5460.31
206_V209_Q0.5460.31
261_A282_G0.5450.31
89_G641_P0.5440.31
87_H165_V0.5440.31
260_M264_A0.5430.31
548_V555_I0.5420.31
65_Y72_V0.5420.31
151_Q575_E0.5410.31
422_E425_L0.5400.31
304_I509_G0.5400.31
26_G443_M0.5380.30
511_L514_V0.5370.30
215_E225_P0.5360.30
271_R283_I0.5350.30
387_G390_F0.5350.30
274_L287_V0.5340.30
211_E229_E0.5340.30
291_V305_R0.5330.30
371_G459_M0.5330.30
221_I231_V0.5330.30
34_G194_G0.5330.30
236_G623_V0.5330.30
97_L150_Q0.5320.30
132_L174_A0.5310.30
191_R292_V0.5310.30
56_C94_R0.5310.30
539_G550_E0.5310.30
129_L156_A0.5310.30
229_E235_G0.5300.30
486_E506_N0.5300.30
173_G218_D0.5290.30
38_A217_R0.5290.30
7_L582_V0.5290.30
385_S438_E0.5280.30
13_S642_V0.5280.30
440_K489_L0.5270.30
528_V542_N0.5270.30
304_I476_V0.5270.30
360_Y422_E0.5260.29
319_D622_T0.5260.29
19_E426_V0.5250.29
146_S172_T0.5250.29
409_R415_H0.5250.29
210_A213_V0.5240.29
154_S609_F0.5230.29
106_N175_L0.5230.29
421_G424_I0.5230.29
81_A196_T0.5220.29
58_D92_F0.5210.29
166_I579_V0.5210.29
10_I512_K0.5210.29
574_I625_G0.5210.29
354_Q464_M0.5210.29
24_L554_E0.5210.29
107_V160_M0.5200.29
155_I171_P0.5190.29
173_G200_V0.5190.29
110_P160_M0.5190.29
484_E487_Q0.5180.29
299_M606_E0.5180.29
203_D206_V0.5180.29
413_F423_V0.5170.29
541_M571_Q0.5170.29
457_S619_L0.5160.29
386_E404_L0.5160.29
453_W457_S0.5160.29
584_G621_S0.5160.29
60_A80_L0.5150.29
35_E45_S0.5150.29
336_L345_V0.5150.29
551_R587_G0.5150.29
428_N638_R0.5140.29
164_Q195_H0.5140.29
424_I618_F0.5140.29
48_S640_D0.5140.29
325_P471_S0.5140.29
328_Q341_K0.5130.28
542_N549_T0.5120.28
282_G572_F0.5120.28
384_F388_N0.5110.28
92_F563_A0.5110.28
54_L60_A0.5110.28
208_A619_L0.5110.28
201_T636_A0.5100.28
346_A475_R0.5100.28
546_V641_P0.5100.28
402_V405_D0.5100.28
113_Y536_G0.5100.28
341_K457_S0.5100.28
181_E205_Q0.5090.28
568_V639_L0.5090.28
235_G585_A0.5080.28
50_L152_R0.5080.28
215_E489_L0.5070.28
289_I514_V0.5070.28
235_G246_G0.5070.28
76_D141_Y0.5070.28
110_P179_S0.5070.28
201_T207_A0.5060.28
37_V55_G0.5060.28
411_Q415_H0.5060.28
112_V260_M0.5050.28
612_L615_L0.5030.28
261_A275_T0.5030.28
303_D307_I0.5020.28
44_G146_S0.5020.28
159_L190_L0.5020.28
557_I624_T0.5020.28
137_R183_V0.5020.28
163_G540_V0.5010.28
257_A579_V0.5010.28
130_Q467_S0.5010.28
149_Q166_I0.5000.27
190_L559_M0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3tuiC 2 0.5247 100 0.548 Contact Map
2pcjA 2 0.3441 100 0.562 Contact Map
3tifA 4 0.3503 100 0.564 Contact Map
4u00A 1 0.3688 100 0.566 Contact Map
2oljA 2 0.3704 100 0.567 Contact Map
4yerA 2 0.4367 100 0.569 Contact Map
4huqB 1 0.4213 100 0.57 Contact Map
1b0uA 2 0.3781 100 0.571 Contact Map
4ymuJ 2 0.3673 100 0.573 Contact Map
1g291 4 0.5401 100 0.574 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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