GREMLIN Database
YBJE - Uncharacterized protein YbjE
UniProt: P75826 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13426
Length: 299 (295)
Sequences: 385 (275)
Seq/√Len: 16.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
255_C259_S3.9551.00
259_S282_H3.9441.00
186_A196_A3.6751.00
258_T263_T3.5270.99
71_V181_G3.3840.99
62_L246_R3.2530.99
213_L294_I3.0960.99
116_V285_I3.0100.98
206_Y241_P2.9240.98
6_L143_L2.8300.97
235_I252_L2.6770.96
209_S229_D2.5970.96
44_M226_F2.5930.96
181_G185_N2.4920.95
147_V254_L2.4890.95
173_V193_I2.4210.94
122_G206_Y2.3600.93
71_V185_N2.3010.92
167_G171_A2.2950.92
201_S208_L2.2760.91
219_P226_F2.2670.91
80_L253_G2.2350.91
282_H286_L2.2330.91
75_C184_I2.2120.90
282_H287_S2.1870.90
267_L275_M2.1830.90
236_A255_C2.1430.89
147_V260_M2.1090.88
45_G208_L2.0660.87
213_L298_S2.0560.87
49_A137_E2.0010.85
70_T74_L1.9990.85
76_N177_S1.9570.84
257_A290_V1.9550.84
87_L184_I1.9420.83
201_S297_F1.9320.83
180_I285_I1.9020.82
39_L70_T1.8790.81
143_L296_F1.8300.79
23_Q117_I1.7250.75
79_A177_S1.6850.73
122_G241_P1.6710.72
46_I78_A1.6580.72
31_Q188_I1.6580.72
260_M287_S1.6450.71
142_L190_D1.6390.71
80_L219_P1.6200.70
151_L214_T1.6070.69
29_I192_P1.5820.68
111_L114_V1.5770.68
213_L221_I1.5700.68
108_S206_Y1.5670.67
144_L287_S1.5620.67
174_V286_L1.5550.67
82_W180_I1.5500.66
199_M290_V1.5480.66
65_S68_S1.5030.64
69_I73_L1.4700.62
214_T292_I1.4680.62
42_F181_G1.4660.62
281_V287_S1.4650.62
111_L230_L1.4590.62
41_L181_G1.4500.61
18_I62_L1.4500.61
40_I177_S1.4490.61
74_L142_L1.4310.60
95_Q113_G1.4220.60
268_Q271_G1.4210.60
212_L239_L1.4210.60
179_L293_L1.4180.59
212_L288_L1.4090.59
37_V211_I1.3940.58
221_I294_I1.3930.58
209_S291_P1.3930.58
74_L78_A1.3890.58
121_I124_S1.3850.57
182_G196_A1.3750.57
236_A277_P1.3750.57
95_Q102_I1.3680.57
45_G201_S1.3670.56
121_I180_I1.3650.56
66_A172_V1.3550.56
183_L187_F1.3490.55
168_M172_V1.3460.55
210_G287_S1.3430.55
252_L275_M1.3420.55
116_V172_V1.3330.55
282_H298_S1.3280.54
194_N237_I1.3280.54
226_F269_R1.3180.54
115_V234_L1.3050.53
67_V238_M1.2780.51
9_L33_L1.2550.50
191_L287_S1.2480.50
49_A246_R1.2150.48
61_I207_S1.2060.47
93_H184_I1.1900.46
42_F274_D1.1860.46
115_V259_S1.1810.46
150_Q265_P1.1800.46
10_V296_F1.1790.46
69_I231_A1.1770.45
161_I281_V1.1740.45
33_L214_T1.1740.45
85_R180_I1.1650.45
170_V298_S1.1600.45
179_L200_A1.1580.44
117_I127_A1.1490.44
258_T272_G1.1410.43
44_M218_G1.1410.43
92_H176_V1.1350.43
195_T259_S1.1310.43
44_M111_L1.1300.43
4_G17_L1.1290.43
38_Y226_F1.1280.43
116_V188_I1.1220.42
69_I279_A1.1190.42
236_A294_I1.1150.42
116_V121_I1.1150.42
152_R229_D1.1140.42
122_G226_F1.0980.41
104_M168_M1.0920.41
29_I32_L1.0870.40
261_D264_L1.0750.40
80_L177_S1.0730.40
152_R177_S1.0720.40
180_I183_L1.0710.39
135_A173_V1.0710.39
123_L234_L1.0670.39
16_Y212_L1.0630.39
287_S298_S1.0620.39
244_I260_M1.0610.39
175_V289_L1.0590.39
118_G264_L1.0580.39
103_A175_V1.0550.39
17_L70_T1.0420.38
261_D283_G1.0410.38
244_I271_G1.0320.37
184_I193_I1.0220.37
41_L230_L1.0210.37
7_I44_M1.0200.37
251_A272_G1.0160.36
8_I41_L1.0030.36
210_G260_M1.0010.36
195_T213_L0.9990.36
108_S111_L0.9890.35
120_A180_I0.9880.35
6_L296_F0.9830.35
117_I188_I0.9830.35
241_P244_I0.9820.35
102_I142_L0.9820.35
108_S241_P0.9790.35
282_H295_A0.9790.35
121_I127_A0.9760.34
49_A123_L0.9750.34
138_Y257_A0.9720.34
241_P268_Q0.9710.34
19_P262_F0.9710.34
48_L271_G0.9690.34
78_A172_V0.9680.34
20_L120_A0.9660.34
36_M237_I0.9650.34
33_L290_V0.9620.34
66_A186_A0.9610.34
197_L297_F0.9580.33
33_L252_L0.9510.33
237_I270_T0.9500.33
229_D290_V0.9470.33
179_L183_L0.9410.33
95_Q245_R0.9400.32
268_Q279_A0.9380.32
152_R244_I0.9310.32
202_G290_V0.9220.32
40_I262_F0.9200.31
85_R106_L0.9180.31
268_Q276_V0.9170.31
56_S176_V0.9160.31
179_L203_F0.9150.31
83_L156_M0.9130.31
146_L237_I0.9110.31
158_L195_T0.9040.31
56_S200_A0.8980.30
229_D277_P0.8950.30
244_I275_M0.8950.30
10_V184_I0.8910.30
217_F298_S0.8910.30
93_H96_E0.8890.30
173_V296_F0.8890.30
169_I172_V0.8880.30
76_N152_R0.8850.30
84_E237_I0.8830.30
73_L77_I0.8820.30
120_A124_S0.8760.29
14_V187_F0.8730.29
43_F198_A0.8710.29
94_Q97_K0.8710.29
97_K231_A0.8630.29
52_D241_P0.8560.28
70_T175_V0.8550.28
45_G234_L0.8550.28
102_I134_E0.8530.28
111_L226_F0.8480.28
128_F238_M0.8480.28
142_L267_L0.8470.28
184_I238_M0.8440.28
43_F274_D0.8430.28
225_A228_N0.8360.27
156_M210_G0.8340.27
41_L263_T0.8330.27
115_V253_G0.8290.27
94_Q180_I0.8280.27
199_M236_A0.8210.27
51_L111_L0.8210.27
209_S225_A0.8200.27
77_I158_L0.8180.27
83_L173_V0.8160.27
66_A120_A0.8110.26
210_G267_L0.8090.26
117_I180_I0.8090.26
27_K31_Q0.8080.26
88_P218_G0.8060.26
214_T252_L0.8060.26
183_L193_I0.8060.26
61_I84_E0.8030.26
41_L209_S0.8030.26
252_L282_H0.8030.26
16_Y44_M0.7960.26
223_S228_N0.7900.25
223_S275_M0.7900.25
182_G218_G0.7890.25
264_L283_G0.7890.25
147_V282_H0.7830.25
13_I50_F0.7820.25
271_G277_P0.7790.25
165_R231_A0.7780.25
58_L206_Y0.7740.25
58_L241_P0.7720.25
221_I225_A0.7720.25
117_I289_L0.7690.24
189_L211_I0.7680.24
223_S244_I0.7670.24
33_L38_Y0.7650.24
187_F193_I0.7610.24
225_A229_D0.7610.24
35_W113_G0.7580.24
99_P173_V0.7560.24
214_T223_S0.7550.24
99_P168_M0.7540.24
222_G258_T0.7530.24
205_W227_F0.7470.24
14_V113_G0.7420.23
36_M201_S0.7420.23
78_A184_I0.7420.23
173_V183_L0.7410.23
144_L205_W0.7400.23
40_I76_N0.7360.23
46_I214_T0.7350.23
8_I96_E0.7340.23
18_I90_R0.7330.23
158_L164_N0.7300.23
117_I121_I0.7290.23
113_G117_I0.7290.23
216_S298_S0.7290.23
23_Q187_F0.7230.23
137_E234_L0.7230.23
227_F231_A0.7220.22
127_A145_F0.7220.22
7_I100_S0.7220.22
148_G233_E0.7200.22
116_V180_I0.7160.22
257_A286_L0.7160.22
19_P66_A0.7140.22
93_H175_V0.7130.22
42_F116_V0.7110.22
147_V181_G0.7110.22
195_T262_F0.7100.22
9_L229_D0.7090.22
174_V282_H0.7090.22
21_R106_L0.7050.22
38_Y48_L0.7050.22
53_N110_K0.7020.22
210_G222_G0.6990.22
138_Y215_E0.6970.21
80_L151_L0.6920.21
4_G33_L0.6900.21
120_A176_V0.6900.21
281_V284_F0.6850.21
116_V134_E0.6850.21
173_V188_I0.6820.21
67_V185_N0.6790.21
141_I216_S0.6790.21
28_V176_V0.6780.21
59_L224_A0.6760.21
206_Y262_F0.6740.21
27_K67_V0.6730.21
281_V286_L0.6720.21
45_G80_L0.6720.21
145_F237_I0.6720.21
47_S171_A0.6720.21
132_A243_L0.6710.20
146_L170_V0.6710.20
76_N174_V0.6700.20
206_Y272_G0.6690.20
219_P251_A0.6690.20
267_L278_A0.6670.20
53_N262_F0.6610.20
87_L235_I0.6600.20
145_F169_I0.6600.20
62_L226_F0.6590.20
118_G222_G0.6590.20
224_A255_C0.6590.20
195_T295_A0.6570.20
21_R66_A0.6520.20
210_G263_T0.6510.20
6_L123_L0.6500.20
195_T217_F0.6500.20
70_T236_A0.6470.20
149_I218_G0.6430.19
60_A63_H0.6420.19
41_L297_F0.6420.19
74_L121_I0.6420.19
33_L237_I0.6410.19
152_R241_P0.6400.19
164_N229_D0.6400.19
185_N192_P0.6400.19
167_G272_G0.6390.19
203_F253_G0.6390.19
18_I29_I0.6380.19
60_A145_F0.6350.19
254_L259_S0.6320.19
68_S235_I0.6300.19
150_Q171_A0.6260.19
182_G186_A0.6260.19
213_L278_A0.6240.19
45_G267_L0.6210.19
90_R117_I0.6200.19
18_I78_A0.6180.19
164_N277_P0.6180.19
154_N236_A0.6170.19
227_F263_T0.6170.19
25_A176_V0.6170.19
75_C172_V0.6150.18
60_A239_L0.6150.18
243_L289_L0.6120.18
176_V274_D0.6110.18
92_H97_K0.6100.18
32_L292_I0.6090.18
124_S184_I0.6060.18
133_T143_L0.6050.18
175_V200_A0.6030.18
115_V230_L0.6030.18
267_L282_H0.6020.18
68_S185_N0.6000.18
111_L241_P0.5970.18
148_G207_S0.5970.18
149_I288_L0.5930.18
170_V254_L0.5920.18
167_G182_G0.5920.18
279_A286_L0.5910.18
111_L171_A0.5910.18
133_T138_Y0.5870.17
199_M248_R0.5860.17
130_Q176_V0.5860.17
14_V70_T0.5850.17
45_G48_L0.5850.17
77_I250_T0.5840.17
39_L285_I0.5830.17
146_L224_A0.5830.17
107_E199_M0.5820.17
32_L95_Q0.5820.17
207_S280_I0.5810.17
177_S192_P0.5790.17
95_Q172_V0.5760.17
108_S150_Q0.5730.17
152_R171_A0.5730.17
43_F231_A0.5710.17
61_I192_P0.5710.17
82_W183_L0.5700.17
210_G258_T0.5670.17
106_L110_K0.5660.17
143_L214_T0.5620.17
70_T183_L0.5620.17
16_Y40_I0.5590.17
248_R251_A0.5570.17
260_M267_L0.5570.17
67_V147_V0.5560.16
161_I260_M0.5560.16
29_I78_A0.5540.16
44_M225_A0.5540.16
152_R155_G0.5530.16
62_L221_I0.5530.16
176_V183_L0.5520.16
54_L241_P0.5520.16
24_A184_I0.5510.16
260_M282_H0.5510.16
211_I236_A0.5500.16
14_V168_M0.5500.16
174_V288_L0.5400.16
44_M234_L0.5380.16
226_F241_P0.5380.16
35_W98_L0.5380.16
22_Q180_I0.5360.16
68_S136_S0.5350.16
71_V190_D0.5340.16
202_G213_L0.5340.16
146_L151_L0.5340.16
213_L225_A0.5310.16
211_I262_F0.5310.16
33_L262_F0.5300.16
198_A297_F0.5280.16
174_V245_R0.5280.16
82_W125_G0.5270.16
238_M297_F0.5260.16
255_C260_M0.5240.15
256_G261_D0.5230.15
18_I109_L0.5220.15
120_A238_M0.5220.15
46_I270_T0.5210.15
235_I242_G0.5200.15
232_R261_D0.5200.15
152_R226_F0.5200.15
237_I288_L0.5190.15
98_L168_M0.5180.15
102_I119_F0.5170.15
174_V298_S0.5170.15
187_F242_G0.5140.15
74_L285_I0.5140.15
230_L236_A0.5140.15
153_N213_L0.5130.15
56_S67_V0.5130.15
55_A64_Y0.5130.15
168_M240_I0.5110.15
85_R187_F0.5110.15
12_L146_L0.5100.15
83_L113_G0.5090.15
78_A117_I0.5060.15
78_A176_V0.5040.15
22_Q32_L0.5030.15
237_I259_S0.5030.15
111_L271_G0.5020.15
18_I86_G0.5000.15
104_M206_Y0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zuxA 1 0.5819 82.1 0.945 Contact Map
4bwzA 2 0.6589 63.1 0.953 Contact Map
4cz8A 2 0.6789 57.5 0.955 Contact Map
2nwlA 3 0.8829 46.9 0.957 Contact Map
4n7wA 2 0.495 39.2 0.959 Contact Map
4czbA 2 0.6689 31.4 0.961 Contact Map
3qnqA 2 0.2977 18.2 0.965 Contact Map
2bg9E 1 0.4448 7.6 0.971 Contact Map
1ldfA 3 0.2843 7.3 0.971 Contact Map
3w4tA 1 0.2742 6.6 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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