GREMLIN Database
YLIE - Putative cyclic di-GMP phosphodiesterase YliE
UniProt: P75800 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13476
Length: 782 (709)
Sequences: 2283 (2039)
Seq/√Len: 76.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
561_A773_W6.5811.00
765_Q768_M5.5741.00
599_K644_E5.4811.00
432_A435_C5.3571.00
709_S713_G5.3171.00
369_S373_Y4.7291.00
553_I759_A4.6291.00
526_E579_K4.5091.00
385_I446_L4.3421.00
742_V759_A4.1821.00
490_N493_S4.1471.00
594_G628_Q4.0271.00
604_E608_F3.9821.00
485_P488_G3.8001.00
676_R703_D3.7911.00
624_V634_F3.7021.00
547_Y604_E3.6661.00
639_T678_Q3.6021.00
641_I645_N3.4761.00
731_R757_V3.4071.00
533_N569_S3.2871.00
600_T603_G3.2321.00
604_E770_F3.1581.00
569_S573_G3.0921.00
544_F568_V2.9251.00
397_G479_K2.9041.00
745_E749_R2.8551.00
552_D555_T2.8501.00
545_L596_Q2.8141.00
565_C597_I2.7891.00
558_I776_S2.7331.00
606_R610_Q2.7291.00
545_L601_A2.6701.00
672_I682_I2.6051.00
570_A573_G2.5811.00
546_V769_P2.5801.00
653_C704_S2.5781.00
460_I481_A2.5271.00
384_A436_D2.5131.00
595_Y637_R2.5111.00
356_M361_I2.5101.00
543_L565_C2.4831.00
698_Y714_D2.4621.00
569_S572_R2.4421.00
413_V499_K2.4331.00
608_F770_F2.4281.00
397_G460_I2.4211.00
745_E763_L2.4091.00
408_E416_R2.3801.00
541_G600_T2.3611.00
400_K503_S2.3451.00
599_K645_N2.3401.00
542_E569_S2.3391.00
748_A759_A2.2651.00
638_F675_L2.2191.00
431_Y437_I2.2181.00
357_K361_I2.2111.00
551_V764_Y2.2071.00
762_Y767_P2.2011.00
442_A503_S2.2001.00
750_E754_L2.1771.00
622_I652_L2.1411.00
769_P772_A2.1211.00
716_F750_E2.1021.00
584_A593_L2.0961.00
545_L565_C2.0851.00
565_C596_Q2.0821.00
356_M360_E2.0811.00
598_I622_I2.0761.00
387_E436_D2.0731.00
596_Q600_T2.0551.00
418_K421_R2.0241.00
389_N432_A2.0241.00
609_S651_S2.0141.00
605_F647_L2.0121.00
550_I653_C2.0051.00
339_R349_I1.9961.00
444_L499_K1.9921.00
361_I364_S1.9811.00
449_C459_K1.9791.00
499_K503_S1.9771.00
419_I475_L1.9681.00
544_F574_I1.9601.00
341_G344_K1.9531.00
345_E349_I1.9511.00
402_C478_H1.9481.00
600_T604_E1.9471.00
683_S704_S1.9371.00
456_F460_I1.9311.00
542_E567_W1.9211.00
545_L597_I1.9181.00
360_E364_S1.9151.00
384_A387_E1.8851.00
602_M652_L1.8811.00
399_I477_I1.8761.00
550_I704_S1.8741.00
395_A483_C1.8511.00
418_K473_R1.8431.00
319_L323_L1.8431.00
344_K347_I1.8171.00
736_P757_V1.8091.00
432_A459_K1.7991.00
488_G497_K1.7971.00
565_C593_L1.7961.00
533_N572_R1.7901.00
642_M647_L1.7891.00
744_S747_V1.7841.00
409_A503_S1.7761.00
704_S738_I1.7521.00
407_V419_I1.7461.00
652_L680_V1.7201.00
364_S368_L1.7101.00
505_I514_I1.6981.00
609_S648_K1.6981.00
681_R703_D1.6921.00
739_A756_C1.6871.00
398_I502_I1.6851.00
413_V503_S1.6851.00
423_L466_F1.6751.00
471_G474_N1.6661.00
624_V654_V1.6641.00
534_I537_A1.6631.00
393_Y486_L1.6561.00
748_A764_Y1.6551.00
405_E503_S1.6441.00
550_I560_G1.6091.00
684_I702_P1.6041.00
404_L420_V1.6001.00
550_I758_Q1.5971.00
568_V574_I1.5911.00
629_L672_I1.5890.99
385_I448_L1.5870.99
608_F774_D1.5810.99
422_K425_Q1.5790.99
409_A499_K1.5760.99
466_F470_F1.5690.99
400_K506_R1.5640.99
715_I750_E1.5440.99
542_E570_A1.5430.99
408_E442_A1.5370.99
400_K409_A1.5350.99
731_R737_V1.5310.99
405_E499_K1.5300.99
354_A358_D1.5140.99
550_I738_I1.5090.99
478_H503_S1.5070.99
534_I543_L1.5070.99
572_R575_I1.5070.99
180_H190_A1.4900.99
452_N455_T1.4880.99
409_A413_V1.4760.99
619_L681_R1.4730.99
727_F754_L1.4670.99
716_F746_D1.4660.99
400_K499_K1.4510.99
578_L709_S1.4510.99
380_I384_A1.4500.99
487_Q515_F1.4440.99
585_E590_I1.4430.99
722_I729_L1.4390.99
403_G510_F1.4370.99
626_P659_T1.4250.99
197_D200_W1.4190.99
569_S575_I1.4140.99
742_V751_L1.4130.99
602_M641_I1.4100.99
716_F720_G1.4000.99
619_L653_C1.3980.99
359_A362_E1.3910.99
530_I583_I1.3840.99
551_V556_R1.3830.99
419_I470_F1.3830.99
441_N503_S1.3800.99
408_E417_N1.3670.98
441_N444_L1.3550.98
358_D361_I1.3510.98
484_E494_Y1.3470.98
485_P494_Y1.3460.98
347_I350_K1.3450.98
416_R442_A1.3360.98
323_L326_L1.3350.98
739_A751_L1.3310.98
341_G345_E1.3310.98
400_K408_E1.3300.98
443_D506_R1.3270.98
748_A763_L1.3260.98
402_C506_R1.3250.98
538_M543_L1.3220.98
344_K349_I1.3210.98
339_R344_K1.3180.98
751_L756_C1.3000.98
720_G750_E1.2960.98
405_E478_H1.2940.98
714_D718_T1.2930.98
724_R732_Y1.2930.98
536_H542_E1.2930.98
581_I657_T1.2920.98
601_A622_I1.2890.98
727_F756_C1.2800.98
642_M680_V1.2700.98
123_Q128_G1.2700.98
484_E488_G1.2690.97
553_I748_A1.2680.97
376_E408_E1.2660.97
367_L370_L1.2650.97
639_T674_Q1.2640.97
460_I463_V1.2590.97
478_H499_K1.2550.97
125_Q129_P1.2540.97
672_I701_N1.2500.97
405_E444_L1.2500.97
598_I652_L1.2480.97
461_A464_N1.2480.97
547_Y563_A1.2440.97
642_M649_A1.2430.97
661_I696_R1.2410.97
322_T329_S1.2380.97
698_Y718_T1.2360.97
376_E417_N1.2340.97
484_E487_Q1.2340.97
373_Y384_A1.2280.97
503_S506_R1.2200.97
478_H506_R1.2190.97
404_L506_R1.2140.97
604_E774_D1.2100.97
315_E319_L1.2020.97
772_A775_K1.2010.96
736_P758_Q1.1990.96
405_E413_V1.1960.96
581_I585_E1.1920.96
398_I446_L1.1900.96
430_K462_M1.1880.96
342_D347_I1.1860.96
400_K443_D1.1840.96
581_I590_I1.1820.96
340_E344_K1.1750.96
442_A478_H1.1740.96
686_D740_E1.1670.96
405_E442_A1.1660.96
470_F475_L1.1650.96
408_E506_R1.1630.96
576_S582_T1.1620.96
759_A764_Y1.1590.96
575_I582_T1.1550.96
442_A499_K1.1540.96
339_R350_K1.1520.96
408_E443_D1.1510.96
598_I654_V1.1500.96
339_R348_S1.1440.95
413_V442_A1.1410.95
401_L477_I1.1390.95
441_N499_K1.1370.95
411_F528_I1.1350.95
338_I344_K1.1340.95
709_S741_G1.1340.95
765_Q776_S1.1330.95
357_K360_E1.1300.95
431_Y435_C1.1290.95
400_K405_E1.1270.95
414_D492_W1.1250.95
657_T740_E1.1220.95
141_D144_P1.1150.95
606_R609_S1.1130.95
404_L408_E1.1130.95
413_V444_L1.1100.95
559_L758_Q1.1090.95
444_L503_S1.1090.95
605_F620_L1.1070.94
724_R728_D1.1030.94
504_S507_D1.0950.94
437_I470_F1.0930.94
65_A69_K1.0920.94
124_E130_L1.0920.94
768_M776_S1.0910.94
344_K348_S1.0910.94
382_N417_N1.0860.94
372_S383_M1.0820.94
725_I732_Y1.0800.94
402_C510_F1.0780.94
546_V574_I1.0780.94
605_F609_S1.0770.94
406_A531_A1.0750.94
444_L478_H1.0750.94
535_R589_F1.0730.93
727_F731_R1.0730.93
416_R506_R1.0700.93
402_C509_M1.0660.93
408_E444_L1.0650.93
333_I349_I1.0640.93
708_D740_E1.0620.93
740_E762_Y1.0570.93
441_N478_H1.0540.93
602_M645_N1.0530.93
401_L423_L1.0520.93
345_E351_N1.0520.93
524_I528_I1.0480.93
647_L652_L1.0470.93
202_Y205_E1.0470.93
567_W573_G1.0450.93
637_R641_I1.0430.93
653_C683_S1.0420.92
707_V726_I1.0420.92
365_N368_L1.0410.92
595_Y599_K1.0410.92
344_K350_K1.0390.92
401_L499_K1.0370.92
527_N586_D1.0310.92
629_L634_F1.0300.92
543_L596_Q1.0270.92
581_I625_S1.0260.92
508_H514_I1.0250.92
602_M647_L1.0230.92
326_L329_S1.0200.92
382_N413_V1.0200.92
409_A444_L1.0180.92
544_F769_P1.0120.91
382_N499_K1.0100.91
634_F638_F1.0090.91
584_A590_I1.0080.91
196_V199_N1.0070.91
330_T356_M1.0070.91
584_A588_G1.0070.91
408_E499_K1.0060.91
360_E363_R1.0020.91
442_A502_I1.0020.91
402_C503_S1.0000.91
727_F757_V1.0000.91
533_N571_E0.9990.91
689_T710_Q0.9970.91
561_A620_L0.9950.91
319_L322_T0.9940.91
338_I349_I0.9930.91
443_D499_K0.9890.90
590_I657_T0.9850.90
665_N668_F0.9840.90
32_Y36_S0.9840.90
427_I437_I0.9830.90
554_N752_I0.9830.90
449_C456_F0.9810.90
622_I680_V0.9780.90
664_I667_H0.9770.90
62_E65_A0.9760.90
747_V763_L0.9740.90
446_L495_A0.9730.90
400_K416_R0.9730.90
426_R470_F0.9720.90
354_A357_K0.9720.90
400_K413_V0.9720.90
405_E506_R0.9720.90
417_N442_A0.9690.89
487_Q497_K0.9680.89
413_V417_N0.9680.89
485_P497_K0.9660.89
550_I619_L0.9660.89
345_E350_K0.9640.89
416_R443_D0.9620.89
416_R499_K0.9610.89
693_N711_F0.9590.89
405_E408_E0.9590.89
316_M319_L0.9550.89
575_I581_I0.9480.88
505_I509_M0.9450.88
121_Y125_Q0.9440.88
403_G531_A0.9430.88
551_V748_A0.9430.88
409_A417_N0.9430.88
601_A620_L0.9410.88
463_V479_K0.9380.88
499_K506_R0.9360.88
533_N570_A0.9350.88
402_C499_K0.9250.87
737_V757_V0.9240.87
424_C437_I0.9240.87
315_E323_L0.9230.87
483_C515_F0.9210.87
176_S197_D0.9190.87
413_V478_H0.9160.87
197_D201_R0.9140.87
330_T349_I0.9140.87
404_L416_R0.9110.86
418_K422_K0.9100.86
606_R645_N0.9100.86
384_A435_C0.9090.86
426_R469_S0.9080.86
606_R646_G0.9080.86
401_L503_S0.9070.86
564_L577_P0.9060.86
460_I479_K0.9050.86
598_I641_I0.9050.86
435_C459_K0.9030.86
536_H540_I0.9010.86
198_L201_R0.9000.86
369_S378_G0.8970.85
715_I723_V0.8960.85
589_F592_E0.8910.85
401_L405_E0.8900.85
634_F700_I0.8880.85
550_I621_H0.8870.85
568_V573_G0.8860.85
702_P735_I0.8850.85
497_K521_L0.8840.85
749_R753_K0.8840.85
405_E502_I0.8820.85
585_E625_S0.8810.84
353_I356_M0.8800.84
642_M652_L0.8800.84
322_T325_F0.8780.84
560_G653_C0.8780.84
413_V506_R0.8760.84
416_R444_L0.8760.84
402_C413_V0.8740.84
749_R752_I0.8740.84
405_E409_A0.8730.84
417_N499_K0.8730.84
676_R682_I0.8700.84
457_T515_F0.8690.84
638_F654_V0.8680.84
609_S612_A0.8670.83
598_I680_V0.8670.83
341_G349_I0.8660.83
316_M328_D0.8630.83
502_I506_R0.8630.83
398_I405_E0.8600.83
531_A535_R0.8600.83
312_Q315_E0.8590.83
349_I356_M0.8590.83
437_I447_L0.8580.83
690_G740_E0.8570.83
408_E478_H0.8530.82
422_K470_F0.8530.82
657_T686_D0.8530.82
533_N567_W0.8470.82
341_G348_S0.8460.82
400_K404_L0.8450.82
376_E442_A0.8450.82
199_N207_L0.8440.82
405_E443_D0.8420.82
704_S736_P0.8400.82
567_W741_G0.8400.82
709_S738_I0.8390.81
547_Y601_A0.8370.81
534_I589_F0.8320.81
416_R503_S0.8310.81
581_I584_A0.8290.81
516_C521_L0.8290.81
324_A327_P0.8270.80
563_A620_L0.8250.80
339_R347_I0.8250.80
463_V511_S0.8240.80
400_K444_L0.8240.80
389_N436_D0.8230.80
374_D439_T0.8220.80
608_F773_W0.8220.80
402_C444_L0.8210.80
773_W777_G0.8200.80
340_E345_E0.8170.80
409_A442_A0.8160.80
370_L550_I0.8160.80
672_I676_R0.8160.80
478_H502_I0.8150.80
400_K442_A0.8140.79
413_V502_I0.8130.79
622_I654_V0.8110.79
363_R370_L0.8110.79
465_D468_S0.8110.79
425_Q428_A0.8100.79
724_R754_L0.8100.79
404_L443_D0.8080.79
422_K426_R0.8080.79
570_A574_I0.8070.79
339_R345_E0.8070.79
375_Q378_G0.8060.79
565_C574_I0.8060.79
707_V723_V0.8060.79
201_R205_E0.8040.79
722_I726_I0.8040.79
404_L444_L0.8040.79
499_K502_I0.8040.79
397_G447_L0.8020.78
583_I587_I0.8020.78
312_Q316_M0.8020.78
382_N416_R0.8020.78
345_E356_M0.8010.78
36_S40_V0.8000.78
558_I618_F0.8000.78
340_E349_I0.7990.78
442_A506_R0.7990.78
51_Q55_G0.7980.78
332_Q349_I0.7980.78
567_W570_A0.7970.78
635_H678_Q0.7950.78
526_E572_R0.7930.78
439_T442_A0.7930.78
366_K370_L0.7930.78
400_K441_N0.7920.78
476_R511_S0.7900.77
43_A47_F0.7880.77
417_N439_T0.7880.77
400_K478_H0.7840.77
46_R50_I0.7830.77
398_I503_S0.7830.77
603_G645_N0.7820.77
553_I742_V0.7820.77
182_N188_L0.7800.76
604_E607_H0.7800.76
661_I684_I0.7790.76
621_H653_C0.7780.76
144_P149_W0.7770.76
517_D520_K0.7760.76
457_T461_A0.7720.76
648_K651_S0.7720.76
366_K369_S0.7710.76
599_K641_I0.7700.76
488_G494_Y0.7700.76
315_E329_S0.7700.76
204_N207_L0.7690.75
530_I533_N0.7690.75
398_I499_K0.7680.75
405_E416_R0.7680.75
611_R774_D0.7670.75
771_S774_D0.7670.75
686_D690_G0.7670.75
727_F737_V0.7660.75
396_V491_A0.7650.75
534_I584_A0.7650.75
413_V441_N0.7650.75
566_R623_N0.7650.75
342_D345_E0.7640.75
415_E472_Y0.7640.75
682_I701_N0.7630.75
403_G406_A0.7630.75
617_D651_S0.7600.75
362_E366_K0.7600.75
382_N444_L0.7560.74
593_L597_I0.7560.74
363_R367_L0.7560.74
551_V776_S0.7550.74
655_E685_D0.7530.74
416_R478_H0.7530.74
55_G59_K0.7530.74
194_I198_L0.7520.74
28_F32_Y0.7500.74
376_E444_L0.7470.73
572_R579_K0.7470.73
400_K417_N0.7460.73
368_L372_S0.7460.73
729_L733_N0.7450.73
453_V486_L0.7440.73
621_H704_S0.7440.73
590_I627_W0.7430.73
402_C502_I0.7410.73
478_H509_M0.7410.73
201_R204_N0.7410.73
399_I447_L0.7390.73
642_M645_N0.7390.73
707_V711_F0.7380.72
427_I592_E0.7370.72
125_Q128_G0.7360.72
673_E677_K0.7350.72
343_A347_I0.7340.72
594_G659_T0.7340.72
318_E322_T0.7330.72
694_L741_G0.7330.72
395_A456_F0.7290.71
398_I498_L0.7290.71
441_N506_R0.7290.71
394_L700_I0.7270.71
382_N408_E0.7260.71
748_A752_I0.7260.71
658_E740_E0.7260.71
316_M326_L0.7260.71
715_I720_G0.7250.71
354_A360_E0.7240.71
607_H611_R0.7220.71
768_M773_W0.7200.71
658_E690_G0.7180.70
654_V682_I0.7180.70
405_E441_N0.7170.70
622_I638_F0.7170.70
340_E348_S0.7160.70
180_H188_L0.7150.70
685_D740_E0.7150.70
721_K732_Y0.7130.70
482_I498_L0.7130.70
386_I492_W0.7120.70
423_L470_F0.7120.70
408_E503_S0.7110.70
341_G350_K0.7100.69
220_K224_E0.7100.69
398_I413_V0.7090.69
686_D708_D0.7090.69
376_E416_R0.7090.69
698_Y711_F0.7090.69
534_I538_M0.7070.69
394_L448_L0.7060.69
694_L711_F0.7060.69
315_E345_E0.7060.69
58_F67_T0.7060.69
629_L700_I0.7050.69
20_A28_F0.7050.69
407_V416_R0.7050.69
654_V680_V0.7040.69
544_F771_S0.7030.69
124_E195_H0.7030.69
315_E349_I0.7020.69
371_I405_E0.7020.69
197_D202_Y0.7010.69
409_A416_R0.7010.69
684_I705_I0.7010.69
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146_K150_S0.7000.68
487_Q494_Y0.6990.68
376_E409_A0.6990.68
700_I713_G0.6980.68
408_E413_V0.6980.68
402_C416_R0.6980.68
592_E595_Y0.6980.68
382_N440_F0.6980.68
61_I64_S0.6970.68
504_S514_I0.6960.68
526_E530_I0.6960.68
598_I638_F0.6950.68
707_V739_A0.6950.68
417_N443_D0.6940.68
546_V568_V0.6940.68
417_N441_N0.6940.68
255_Y268_F0.6930.68
349_I353_I0.6930.68
143_N147_R0.6930.68
402_C408_E0.6930.68
413_V416_R0.6920.68
530_I567_W0.6920.68
566_R577_P0.6910.67
376_E499_K0.6890.67
662_E665_N0.6890.67
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705_I730_A0.6880.67
164_Y176_S0.6880.67
629_L659_T0.6880.67
478_H510_F0.6850.67
587_I590_I0.6850.67
408_E420_V0.6850.67
535_R660_V0.6830.67
629_L668_F0.6830.67
382_N441_N0.6820.66
530_I572_R0.6820.66
653_C758_Q0.6820.66
710_Q722_I0.6820.66
123_Q131_V0.6820.66
624_V628_Q0.6820.66
447_L462_M0.6820.66
587_I592_E0.6810.66
178_T195_H0.6810.66
638_F680_V0.6790.66
174_C180_H0.6780.66
463_V513_F0.6770.66
39_A43_A0.6770.66
622_I647_L0.6760.66
565_C572_R0.6740.65
545_L563_A0.6740.65
711_F740_E0.6740.65
541_G599_K0.6740.65
346_I349_I0.6710.65
564_L740_E0.6710.65
424_C427_I0.6700.65
376_E404_L0.6700.65
339_R346_I0.6690.65
404_L499_K0.6690.65
417_N478_H0.6680.65
344_K351_N0.6680.65
139_F144_P0.6660.65
401_L441_N0.6660.65
541_G596_Q0.6660.65
658_E686_D0.6660.65
388_S489_E0.6660.65
409_A506_R0.6660.65
323_L329_S0.6650.64
251_V255_Y0.6640.64
629_L660_V0.6630.64
400_K439_T0.6620.64
118_I128_G0.6620.64
657_T690_G0.6610.64
315_E347_I0.6600.64
443_D478_H0.6600.64
174_C178_T0.6590.64
355_E361_I0.6560.63
639_T680_V0.6560.63
128_G132_D0.6560.63
385_I438_V0.6560.63
123_Q129_P0.6550.63
35_V39_A0.6550.63
548_Q692_S0.6540.63
376_E400_K0.6540.63
215_E220_K0.6540.63
635_H639_T0.6520.63
299_L306_T0.6520.63
493_S497_K0.6520.63
500_L516_C0.6510.63
566_R655_E0.6500.63
53_N61_I0.6500.63
568_V572_R0.6500.63
564_L658_E0.6500.63
627_W660_V0.6490.63
342_D349_I0.6490.63
316_M324_A0.6480.62
139_F142_F0.6480.62
132_D137_V0.6480.62
382_N404_L0.6470.62
623_N685_D0.6470.62
564_L655_E0.6470.62
389_N434_C0.6460.62
417_N506_R0.6460.62
514_I517_D0.6460.62
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705_I735_I0.6440.62
345_E348_S0.6440.62
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748_A765_Q0.6420.62
333_I355_E0.6420.62
409_A478_H0.6410.62
431_Y447_L0.6410.62
656_I672_I0.6400.61
188_L191_V0.6380.61
274_Y279_L0.6370.61
715_I730_A0.6360.61
402_C443_D0.6350.61
424_C428_A0.6350.61
417_N444_L0.6350.61
463_V476_R0.6340.61
684_I729_L0.6340.61
630_N663_R0.6330.61
372_S510_F0.6330.61
123_Q127_N0.6330.61
595_Y631_E0.6320.61
356_M364_S0.6310.60
598_I602_M0.6310.60
446_L572_R0.6310.60
704_S737_V0.6300.60
482_I497_K0.6300.60
333_I354_A0.6300.60
299_L303_L0.6290.60
409_A441_N0.6290.60
198_L203_L0.6280.60
635_H671_N0.6270.60
402_C405_E0.6270.60
414_D496_E0.6270.60
612_A616_D0.6260.60
623_N655_E0.6260.60
312_Q323_L0.6260.60
119_V124_E0.6260.60
427_I431_Y0.6250.60
64_S67_T0.6250.60
316_M323_L0.6240.60
690_G762_Y0.6240.60
160_W163_A0.6240.60
567_W756_C0.6240.60
413_V443_D0.6230.59
376_E439_T0.6230.59
673_E701_N0.6220.59
704_S758_Q0.6200.59
408_E439_T0.6190.59
531_A560_G0.6190.59
686_D689_T0.6180.59
680_V705_I0.6180.59
741_G747_V0.6180.59
581_I690_G0.6180.59
49_L53_N0.6180.59
655_E706_K0.6170.59
204_N208_D0.6170.59
467_D511_S0.6160.59
592_E628_Q0.6160.59
319_L329_S0.6150.58
408_E441_N0.6140.58
352_S356_M0.6140.58
158_N163_A0.6130.58
698_Y722_I0.6130.58
208_D211_S0.6130.58
690_G708_D0.6120.58
359_A527_N0.6110.58
453_V457_T0.6110.58
40_V44_D0.6100.58
671_N674_Q0.6100.58
278_N282_A0.6100.58
500_L524_I0.6090.58
425_Q429_E0.6070.57
380_I436_D0.6070.57
200_W204_N0.6060.57
709_S762_Y0.6050.57
500_L520_K0.6050.57
137_V144_P0.6050.57
441_N502_I0.6050.57
552_D557_A0.6040.57
404_L503_S0.6040.57
713_G747_V0.6020.57
687_F726_I0.6020.57
444_L506_R0.6010.57
585_E657_T0.6010.57
440_F446_L0.6000.57
43_A69_K0.6000.57
350_K356_M0.6000.57
505_I512_E0.5990.56
215_E229_N0.5990.56
656_I665_N0.5970.56
353_I422_K0.5970.56
153_S156_S0.5970.56
591_N631_E0.5960.56
320_V323_L0.5960.56
404_L439_T0.5950.56
544_F572_R0.5950.56
382_N443_D0.5950.56
376_E506_R0.5940.56
216_V229_N0.5930.56
443_D503_S0.5920.56
407_V485_P0.5920.56
402_C409_A0.5920.56
498_L501_A0.5920.56
410_V528_I0.5920.56
487_Q521_L0.5920.56
196_V200_W0.5920.56
567_W694_L0.5910.55
537_A542_E0.5910.55
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564_L762_Y0.5900.55
553_I593_L0.5900.55
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640_T644_E0.5840.55
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656_I660_V0.5830.54
128_G131_V0.5830.54
198_L543_L0.5830.54
520_K694_L0.5830.54
545_L600_T0.5830.54
759_A763_L0.5820.54
706_K760_Q0.5820.54
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28_F43_A0.5790.54
118_I122_H0.5780.54
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705_I731_R0.5780.54
25_G29_I0.5780.54
21_L33_Q0.5770.54
657_T762_Y0.5760.54
636_E674_Q0.5760.54
24_I28_F0.5750.53
404_L478_H0.5750.53
199_N204_N0.5750.53
691_L740_E0.5750.53
560_G758_Q0.5740.53
323_L327_P0.5740.53
330_T357_K0.5740.53
404_L409_A0.5730.53
565_C598_I0.5730.53
768_M772_A0.5720.53
43_A61_I0.5720.53
318_E321_N0.5720.53
657_T689_T0.5710.53
626_P656_I0.5710.53
560_G619_L0.5710.53
389_N435_C0.5710.53
716_F723_V0.5710.53
198_L205_E0.5710.53
404_L442_A0.5710.53
385_I672_I0.5690.53
432_A436_D0.5690.53
402_C476_R0.5690.53
577_P740_E0.5680.53
396_V448_L0.5680.53
118_I123_Q0.5680.53
309_F312_Q0.5680.53
552_D559_L0.5670.52
551_V558_I0.5660.52
398_I479_K0.5660.52
382_N400_K0.5640.52
657_T711_F0.5630.52
484_E515_F0.5630.52
124_E131_V0.5620.52
567_W709_S0.5620.52
413_V439_T0.5620.52
338_I348_S0.5620.52
372_S384_A0.5610.52
311_R314_S0.5610.52
50_I61_I0.5610.52
550_I612_A0.5600.52
605_F645_N0.5590.51
531_A583_I0.5590.51
397_G481_A0.5580.51
139_F150_S0.5580.51
322_T327_P0.5580.51
655_E740_E0.5570.51
371_I503_S0.5570.51
480_S498_L0.5560.51
202_Y206_Y0.5560.51
476_R503_S0.5560.51
655_E658_E0.5560.51
161_N268_F0.5560.51
217_L223_H0.5550.51
403_G586_D0.5550.51
700_I776_S0.5550.51
322_T326_L0.5540.51
353_I358_D0.5540.51
432_A440_F0.5530.51
409_A502_I0.5530.51
116_D124_E0.5520.51
416_R420_V0.5520.51
32_Y43_A0.5520.51
560_G634_F0.5510.50
463_V477_I0.5510.50
707_V756_C0.5500.50
201_R214_D0.5500.50
686_D711_F0.5480.50
330_T350_K0.5480.50
708_D762_Y0.5470.50
698_Y721_K0.5470.50
770_F774_D0.5460.50
623_N740_E0.5460.50
195_H199_N0.5460.50
658_E688_G0.5460.50
350_K537_A0.5450.50
509_M516_C0.5440.50
306_T310_R0.5430.49
244_N248_I0.5430.49
705_I723_V0.5430.49
436_D675_L0.5420.49
349_I352_S0.5420.49
629_L671_N0.5420.49
199_N202_Y0.5420.49
218_F256_I0.5420.49
24_I66_L0.5410.49
685_D706_K0.5410.49
675_L682_I0.5400.49
202_Y207_L0.5400.49
397_G449_C0.5390.49
481_A515_F0.5390.49
516_C678_Q0.5390.49
401_L444_L0.5390.49
376_E478_H0.5380.49
338_I341_G0.5380.49
402_C477_I0.5380.49
381_K404_L0.5380.49
376_E405_E0.5370.49
456_F459_K0.5370.49
307_R312_Q0.5370.49
564_L623_N0.5360.49
208_D214_D0.5360.49
686_D693_N0.5360.49
612_A651_S0.5360.49
395_A462_M0.5350.48
225_I230_Q0.5350.48
308_V311_R0.5350.48
561_A605_F0.5350.48
705_I733_N0.5350.48
40_V43_A0.5350.48
688_G740_E0.5340.48
469_S691_L0.5340.48
466_F477_I0.5340.48
476_R524_I0.5340.48
331_D334_E0.5330.48
169_R203_L0.5330.48
357_K364_S0.5330.48
588_G657_T0.5330.48
567_W729_L0.5320.48
481_A513_F0.5320.48
700_I758_Q0.5320.48
182_N190_A0.5320.48
410_V524_I0.5310.48
713_G718_T0.5310.48
394_L483_C0.5310.48
590_I628_Q0.5310.48
310_R314_S0.5300.48
169_R174_C0.5290.48
745_E748_A0.5290.48
62_E66_L0.5280.47
387_E451_E0.5280.47
43_A55_G0.5280.47
367_L704_S0.5270.47
27_F34_L0.5260.47
608_F612_A0.5260.47
608_F680_V0.5250.47
459_K640_T0.5250.47
367_L423_L0.5240.47
560_G741_G0.5240.47
405_E510_F0.5240.47
400_K509_M0.5240.47
530_I661_I0.5240.47
655_E688_G0.5230.47
726_I738_I0.5230.47
119_V125_Q0.5230.47
63_R67_T0.5220.47
369_S372_S0.5220.47
721_K725_I0.5220.47
27_F30_I0.5220.47
275_P285_K0.5210.47
402_C419_I0.5210.47
371_I444_L0.5210.47
402_C442_A0.5210.47
595_Y628_Q0.5190.46
714_D721_K0.5190.46
257_E261_A0.5190.46
742_V748_A0.5190.46
297_V301_V0.5180.46
653_C681_R0.5180.46
712_T756_C0.5180.46
275_P279_L0.5180.46
119_V122_H0.5180.46
62_E67_T0.5170.46
631_E668_F0.5170.46
590_I602_M0.5160.46
184_K187_D0.5150.46
403_G684_I0.5130.46
685_D688_G0.5130.46
641_I644_E0.5130.46
21_L24_I0.5130.46
693_N696_R0.5130.46
243_G259_T0.5130.46
439_T506_R0.5130.46
421_R425_Q0.5130.46
695_K710_Q0.5120.45
40_V48_E0.5120.45
200_W203_L0.5110.45
123_Q130_L0.5110.45
565_C592_E0.5110.45
687_F696_R0.5110.45
443_D480_S0.5110.45
635_H674_Q0.5100.45
57_F60_D0.5100.45
346_I350_K0.5100.45
642_M648_K0.5090.45
601_A638_F0.5090.45
661_I758_Q0.5080.45
577_P762_Y0.5070.45
305_T309_F0.5070.45
195_H200_W0.5060.45
625_S751_L0.5060.45
395_A499_K0.5060.45
538_M575_I0.5050.45
385_I403_G0.5050.45
144_P150_S0.5040.44
631_E634_F0.5040.44
422_K684_I0.5040.44
667_H671_N0.5030.44
367_L584_A0.5030.44
603_G607_H0.5020.44
410_V661_I0.5020.44
372_S380_I0.5020.44
548_Q566_R0.5020.44
370_L484_E0.5020.44
398_I440_F0.5020.44
404_L441_N0.5020.44
561_A618_F0.5010.44
689_T740_E0.5010.44
534_I567_W0.5000.44
485_P515_F0.5000.44
384_A502_I0.5000.44
646_G652_L0.5000.44
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rnhA 2 0.5128 100 0.403 Contact Map
4j40A 2 0.3197 100 0.413 Contact Map
3pjxA 1 0.5141 100 0.432 Contact Map
3gfzA 2 0.4693 100 0.5 Contact Map
4hjfA 1 0.3312 100 0.521 Contact Map
4hu4A 1 0.3107 100 0.593 Contact Map
4kieA 1 0.3312 100 0.594 Contact Map
3sy8A 6 0.4987 100 0.598 Contact Map
4rniA 2 0.3223 100 0.598 Contact Map
2r6oA 2 0.3274 100 0.599 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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