GSIB - ECOLI - GREMLIN Contacts

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GSIB - Glutathione-binding protein GsiB

UniProt:	P75797	Sequences: MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPYDANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGITYTVKLREGIKFQDGTDFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAHPATAMISPAALEKYGKEIGFYPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSITWRPVADNNTRAAMLQTGEAQFAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVTQKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKARELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEVEGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFEDADLQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13473
Length:	512 (484)
Sequences:	23054 (17560)
Seq/√Len:	798.2

ECOLI - GSIB SAPA DDPA DPPA OPPA MPPA YGIS NIKA YEJA YBAE SGRR
BACSU - OPPA APPA DPPE YHJP
HALSA - Q9HMI3 Q9HMW4
SULSO - Q97VF7 Q97UG7 Q97VK5 Q97UH5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
191_D	202_K	4.119	1.00
138_I	144_K	3.206	1.00
136_E	144_K	3.176	1.00
284_K	340_E	3.129	1.00
94_E	141_T	3.032	1.00
333_K	336_E	3.029	1.00
110_K	114_D	2.897	1.00
139_D	142_T	2.840	1.00
446_D	450_Q	2.806	1.00
426_S	440_S	2.790	1.00
296_P	300_K	2.748	1.00
189_E	202_K	2.693	1.00
454_T	459_E	2.690	1.00
348_S	377_K	2.566	1.00
278_K	281_D	2.548	1.00
110_K	137_A	2.538	1.00
291_Y	333_K	2.498	1.00
78_S	91_K	2.433	1.00
336_E	340_E	2.382	1.00
294_N	297_A	2.375	1.00
29_D	217_S	2.366	1.00
289_L	371_L	2.354	1.00
168_P	172_E	2.345	1.00
426_S	445_D	2.337	1.00
104_F	185_T	2.304	1.00
66_D	70_K	2.299	1.00
443_Q	446_D	2.296	1.00
87_T	144_K	2.280	1.00
80_T	91_K	2.274	1.00
350_T	379_Q	2.263	1.00
102_T	169_A	2.201	1.00
136_E	146_T	2.197	1.00
439_Y	474_E	2.181	1.00
89_T	144_K	2.177	1.00
283_P	287_E	2.175	1.00
63_F	79_Y	2.165	1.00
99_Q	204_F	2.146	1.00
107_A	137_A	2.139	1.00
284_K	287_E	2.131	1.00
66_D	72_K	2.119	1.00
97_K	103_D	2.116	1.00
459_E	462_R	2.103	1.00
372_A	377_K	2.095	1.00
200_K	217_S	2.087	1.00
133_A	148_K	2.073	1.00
284_K	337_L	2.071	1.00
82_S	86_I	2.055	1.00
97_K	206_G	2.039	1.00
87_T	146_T	2.033	1.00
450_Q	463_L	2.023	1.00
441_N	470_I	2.005	1.00
81_V	88_Y	1.971	1.00
60_Q	74_V	1.962	1.00
441_N	474_E	1.959	1.00
232_M	237_E	1.950	1.00
456_D	459_E	1.944	1.00
96_I	104_F	1.920	1.00
91_K	142_T	1.914	1.00
107_A	168_P	1.909	1.00
277_Q	403_R	1.906	1.00
29_D	219_T	1.898	1.00
462_R	466_A	1.847	1.00
194_N	197_D	1.831	1.00
33_A	238_A	1.812	1.00
113_L	145_I	1.808	1.00
42_D	115_R	1.793	1.00
192_T	200_K	1.786	1.00
368_Q	372_A	1.777	1.00
444_V	467_A	1.764	1.00
108_A	168_P	1.751	1.00
189_E	205_A	1.745	1.00
451_A	464_Y	1.743	1.00
77_E	94_E	1.743	1.00
133_A	146_T	1.742	1.00
391_E	401_G	1.741	1.00
273_M	478_I	1.733	1.00
16_A	19_L	1.731	1.00
425_A	449_A	1.728	1.00
105_N	108_A	1.725	1.00
192_T	198_F	1.720	1.00
283_P	474_E	1.716	1.00
202_K	217_S	1.715	1.00
28_K	216_D	1.712	1.00
109_V	143_V	1.710	1.00
447_F	466_A	1.694	1.00
292_A	374_V	1.693	1.00
443_Q	466_A	1.689	1.00
443_Q	470_I	1.685	1.00
310_A	482_V	1.659	1.00
31_V	219_T	1.657	1.00
77_E	91_K	1.640	1.00
198_F	219_T	1.622	1.00
469_D	473_Q	1.616	1.00
95_G	103_D	1.611	1.00
191_D	217_S	1.607	1.00
442_K	446_D	1.599	1.00
451_A	463_L	1.586	1.00
203_K	216_D	1.584	1.00
100_D	167_S	1.579	1.00
384_D	387_Q	1.577	1.00
134_K	146_T	1.576	1.00
82_S	87_T	1.572	1.00
107_A	110_K	1.566	1.00
330_D	333_K	1.563	1.00
348_S	379_Q	1.560	1.00
234_Q	251_L	1.549	1.00
194_N	198_F	1.546	1.00
107_A	140_P	1.541	1.00
287_E	333_K	1.536	1.00
296_P	309_P	1.518	1.00
77_E	93_R	1.517	1.00
105_N	140_P	1.516	1.00
102_T	167_S	1.508	1.00
352_W	381_T	1.487	1.00
447_F	463_L	1.484	1.00
466_A	469_D	1.480	1.00
293_I	367_T	1.475	1.00
63_F	90_V	1.463	1.00
287_E	475_S	1.454	1.00
276_T	438_F	1.453	1.00
223_V	232_M	1.451	1.00
82_S	89_T	1.439	1.00
273_M	404_M	1.434	1.00
463_L	466_A	1.429	1.00
106_A	137_A	1.428	1.00
361_Q	365_Q	1.425	1.00
200_K	219_T	1.424	1.00
60_Q	208_W	1.419	1.00
250_T	253_E	1.415	1.00
390_A	399_E	1.413	1.00
89_T	142_T	1.399	1.00
461_T	465_K	1.399	1.00
454_T	463_L	1.390	1.00
188_Y	215_L	1.386	1.00
79_Y	90_V	1.383	1.00
283_P	473_Q	1.378	1.00
290_N	475_S	1.370	1.00
332_V	335_R	1.364	1.00
339_K	344_P	1.352	1.00
381_T	391_E	1.351	1.00
440_S	445_D	1.336	1.00
335_R	339_K	1.328	1.00
350_T	377_K	1.327	1.00
60_Q	185_T	1.324	1.00
48_D	51_S	1.324	1.00
299_V	309_P	1.315	1.00
462_R	465_K	1.312	1.00
470_I	474_E	1.310	1.00
99_Q	189_E	1.306	1.00
137_A	140_P	1.298	1.00
97_K	204_F	1.294	1.00
370_Q	373_Q	1.290	1.00
289_L	376_I	1.289	1.00
167_S	170_A	1.286	1.00
257_N	491_K	1.279	1.00
110_K	135_T	1.278	1.00
138_I	142_T	1.277	1.00
450_Q	459_E	1.277	1.00
31_V	221_R	1.276	1.00
415_E	460_K	1.268	1.00
259_E	491_K	1.268	1.00
100_D	169_A	1.266	1.00
459_E	463_L	1.264	1.00
191_D	200_K	1.264	1.00
446_D	449_A	1.261	1.00
96_I	185_T	1.259	1.00
277_Q	281_D	1.255	1.00
103_D	141_T	1.254	1.00
145_I	154_F	1.252	1.00
350_T	381_T	1.249	1.00
31_V	239_Q	1.249	1.00
447_F	470_I	1.244	1.00
285_V	338_L	1.223	1.00
91_K	141_T	1.223	1.00
104_F	165_M	1.217	1.00
232_M	238_A	1.210	1.00
33_A	229_R	1.208	1.00
280_F	289_L	1.204	1.00
149_Q	453_K	1.197	1.00
30_V	240_F	1.190	1.00
369_Q	373_Q	1.185	1.00
201_V	220_W	1.182	1.00
73_N	79_Y	1.182	1.00
366_F	370_Q	1.178	1.00
198_F	221_R	1.170	1.00
458_A	461_T	1.168	1.00
209_Q	212_L	1.164	1.00
114_D	118_D	1.160	1.00
285_V	341_A	1.156	1.00
233_L	488_A	1.156	1.00
99_Q	206_G	1.153	1.00
299_V	307_A	1.152	1.00
93_R	96_I	1.152	1.00
272_S	405_F	1.152	1.00
443_Q	447_F	1.151	1.00
385_A	389_A	1.150	1.00
450_Q	454_T	1.147	1.00
316_P	482_V	1.146	1.00
64_G	74_V	1.146	1.00
297_A	370_Q	1.141	1.00
337_L	340_E	1.140	1.00
336_E	339_K	1.136	1.00
439_Y	444_V	1.135	1.00
371_L	378_A	1.134	1.00
331_P	335_R	1.132	1.00
239_Q	492_N	1.126	1.00
112_N	165_M	1.121	1.00
88_Y	154_F	1.120	1.00
368_Q	380_V	1.114	1.00
75_L	185_T	1.112	1.00
64_G	72_K	1.110	1.00
131_N	151_F	1.105	1.00
239_Q	490_S	1.103	1.00
93_R	208_W	1.103	1.00
109_V	165_M	1.101	1.00
303_F	481_V	1.096	1.00
80_T	89_T	1.092	1.00
292_A	371_L	1.089	1.00
344_P	347_F	1.087	1.00
15_I	18_A	1.086	1.00
103_D	140_P	1.085	1.00
458_A	462_R	1.085	1.00
400_S	438_F	1.084	1.00
283_P	475_S	1.082	1.00
17_T	20_M	1.081	1.00
470_I	473_Q	1.077	1.00
262_A	484_K	1.077	1.00
259_E	489_H	1.075	1.00
261_M	489_H	1.071	1.00
203_K	213_P	1.070	1.00
54_V	201_V	1.069	1.00
189_E	204_F	1.065	1.00
353_S	382_A	1.065	1.00
250_T	254_K	1.064	1.00
99_Q	183_V	1.059	1.00
135_T	143_V	1.056	1.00
287_E	337_L	1.056	1.00
90_V	145_I	1.048	1.00
170_A	183_V	1.048	1.00
321_A	465_K	1.046	1.00
447_F	467_A	1.037	1.00
308_T	484_K	1.036	1.00
331_P	374_V	1.035	1.00
368_Q	378_A	1.034	1.00
450_Q	466_A	1.031	1.00
111_A	168_P	1.029	1.00
351_L	378_A	1.028	1.00
447_F	450_Q	1.016	1.00
234_Q	255_N	1.012	1.00
75_L	96_I	1.012	1.00
114_D	117_S	1.011	1.00
30_V	215_L	1.001	1.00
332_V	336_E	0.998	1.00
169_A	173_K	0.998	1.00
228_T	232_M	0.993	1.00
11_V	14_G	0.992	1.00
108_A	111_A	0.991	1.00
417_D	452_L	0.991	1.00
449_A	453_K	0.987	1.00
77_E	141_T	0.984	1.00
369_Q	372_A	0.984	1.00
290_N	295_R	0.982	1.00
75_L	109_V	0.978	1.00
88_Y	155_I	0.978	1.00
367_T	371_L	0.977	1.00
154_F	158_L	0.973	1.00
106_A	138_I	0.970	1.00
98_F	108_A	0.970	1.00
444_V	471_I	0.968	1.00
273_M	289_L	0.966	1.00
284_K	341_A	0.960	1.00
86_I	133_A	0.959	1.00
203_K	212_L	0.957	1.00
300_K	305_G	0.955	1.00
387_Q	391_E	0.952	1.00
107_A	111_A	0.949	1.00
333_K	337_L	0.949	1.00
421_S	452_L	0.946	1.00
89_T	138_I	0.945	1.00
91_K	94_E	0.944	1.00
451_A	467_A	0.943	1.00
28_K	214_K	0.942	1.00
13_L	16_A	0.940	1.00
18_A	21_A	0.938	1.00
88_Y	147_L	0.938	1.00
177_E	180_F	0.938	1.00
106_A	143_V	0.936	1.00
231_A	234_Q	0.934	1.00
383_M	391_E	0.933	1.00
291_Y	327_W	0.933	1.00
364_L	380_V	0.933	1.00
298_L	363_V	0.932	1.00
202_K	205_A	0.931	1.00
299_V	481_V	0.929	1.00
297_A	301_V	0.925	1.00
287_E	291_Y	0.925	1.00
63_F	155_I	0.922	1.00
444_V	448_L	0.917	1.00
61_G	74_V	0.916	1.00
37_N	193_W	0.915	1.00
238_A	241_A	0.915	1.00
99_Q	184_G	0.914	1.00
94_E	103_D	0.910	1.00
439_Y	476_P	0.910	1.00
362_K	365_Q	0.908	1.00
111_A	171_L	0.906	1.00
290_N	478_I	0.905	1.00
303_F	307_A	0.905	1.00
151_F	157_I	0.898	1.00
252_L	258_I	0.897	1.00
457_P	461_T	0.897	1.00
76_A	90_V	0.896	1.00
352_W	379_Q	0.896	1.00
230_A	234_Q	0.895	1.00
248_Q	251_L	0.889	1.00
392_V	405_F	0.888	1.00
331_P	373_Q	0.887	1.00
58_F	201_V	0.884	1.00
30_V	493_L	0.882	1.00
287_E	473_Q	0.878	1.00
91_K	139_D	0.878	1.00
147_L	154_F	0.877	1.00
86_I	146_T	0.877	1.00
308_T	316_P	0.872	1.00
444_V	470_I	0.871	1.00
63_F	76_A	0.871	1.00
253_E	262_A	0.871	1.00
82_S	85_G	0.868	1.00
99_Q	190_L	0.868	1.00
100_D	183_V	0.865	1.00
60_Q	207_Y	0.862	1.00
84_D	87_T	0.861	1.00
294_N	370_Q	0.861	1.00
61_G	164_A	0.858	1.00
343_Y	346_G	0.852	1.00
153_A	415_E	0.849	1.00
131_N	149_Q	0.848	1.00
467_A	470_I	0.845	1.00
465_K	469_D	0.844	1.00
321_A	469_D	0.844	1.00
110_K	143_V	0.843	1.00
28_K	215_L	0.841	1.00
188_Y	213_P	0.841	1.00
193_W	199_V	0.840	1.00
81_V	85_G	0.840	1.00
63_F	71_L	0.833	1.00
280_F	349_T	0.833	1.00
295_R	309_P	0.832	1.00
425_A	448_L	0.827	1.00
448_L	467_A	0.827	1.00
233_L	258_I	0.825	1.00
357_H	360_A	0.824	1.00
424_F	471_I	0.824	1.00
450_Q	453_K	0.821	1.00
258_I	488_A	0.819	1.00
233_L	241_A	0.818	1.00
223_V	238_A	0.814	1.00
90_V	155_I	0.814	1.00
329_Y	373_Q	0.814	1.00
272_S	437_A	0.813	1.00
249_A	253_E	0.812	1.00
347_F	376_I	0.811	1.00
19_L	22_S	0.811	1.00
291_Y	337_L	0.806	1.00
230_A	252_L	0.806	1.00
96_I	141_T	0.806	1.00
334_A	374_V	0.805	1.00
267_M	410_S	0.801	1.00
255_N	258_I	0.800	1.00
75_L	104_F	0.799	1.00
131_N	148_K	0.798	1.00
114_D	135_T	0.797	1.00
421_S	425_A	0.797	1.00
203_K	215_L	0.797	1.00
96_I	208_W	0.795	1.00
137_A	143_V	0.795	1.00
58_F	190_L	0.795	1.00
59_Y	184_G	0.795	1.00
245_P	248_Q	0.792	1.00
19_L	23_C	0.792	1.00
313_V	479_P	0.787	1.00
37_N	222_P	0.786	1.00
231_A	235_T	0.786	1.00
417_D	421_S	0.785	1.00
466_A	470_I	0.783	1.00
435_N	438_F	0.783	1.00
32_V	240_F	0.783	1.00
282_N	341_A	0.780	1.00
250_T	304_A	0.780	1.00
271_I	367_T	0.778	1.00
343_Y	347_F	0.776	1.00
44_Y	115_R	0.776	1.00
282_N	343_Y	0.775	1.00
424_F	477_W	0.771	1.00
108_A	112_N	0.771	1.00
361_Q	382_A	0.771	1.00
353_S	380_V	0.770	1.00
57_S	201_V	0.765	1.00
95_G	141_T	0.765	1.00
417_D	464_Y	0.762	1.00
387_Q	390_A	0.761	1.00
292_A	331_P	0.759	1.00
190_L	199_V	0.758	1.00
285_V	343_Y	0.753	1.00
205_A	216_D	0.748	1.00
90_V	158_L	0.745	1.00
365_Q	380_V	0.744	1.00
264_P	484_K	0.744	1.00
92_L	104_F	0.743	1.00
132_I	135_T	0.742	1.00
262_A	306_Y	0.742	1.00
271_I	404_M	0.741	1.00
86_I	149_Q	0.740	1.00
372_A	376_I	0.739	1.00
293_I	298_L	0.739	1.00
229_R	241_A	0.738	1.00
288_A	338_L	0.738	1.00
201_V	218_I	0.737	1.00
137_A	144_K	0.734	1.00
118_D	121_N	0.734	1.00
337_L	341_A	0.733	1.00
321_A	324_Y	0.732	1.00
349_T	378_A	0.731	1.00
275_V	476_P	0.730	1.00
74_V	208_W	0.729	1.00
353_S	364_L	0.725	1.00
24_A	27_A	0.724	1.00
349_T	404_M	0.722	1.00
252_L	488_A	0.718	1.00
262_A	486_V	0.717	1.00
442_K	445_D	0.716	1.00
37_N	195_Q	0.715	1.00
112_N	166_I	0.714	1.00
176_K	179_G	0.714	1.00
439_Y	470_I	0.713	1.00
388_R	405_F	0.713	1.00
269_R	360_A	0.711	1.00
62_L	76_A	0.710	1.00
276_T	400_S	0.709	1.00
371_L	404_M	0.708	1.00
298_L	366_F	0.706	1.00
14_G	18_A	0.704	1.00
365_Q	368_Q	0.704	1.00
460_K	464_Y	0.703	1.00
180_F	195_Q	0.702	1.00
30_V	218_I	0.701	1.00
9_G	12_A	0.700	1.00
293_I	371_L	0.700	1.00
13_L	18_A	0.699	1.00
106_A	110_K	0.699	1.00
273_M	280_F	0.697	1.00
241_A	244_I	0.697	1.00
312_G	468_Q	0.697	1.00
169_A	172_E	0.697	1.00
46_A	55_A	0.696	1.00
202_K	216_D	0.696	1.00
320_Y	323_S	0.695	1.00
289_L	404_M	0.694	1.00
291_Y	329_Y	0.693	1.00
57_S	218_I	0.693	1.00
43_P	166_I	0.692	1.00
15_I	19_L	0.692	1.00
221_R	232_M	0.691	1.00
383_M	387_Q	0.690	1.00
167_S	183_V	0.690	1.00
33_A	223_V	0.687	1.00
353_S	356_N	0.687	1.00
111_A	172_E	0.686	1.00
372_A	378_A	0.685	1.00
18_A	22_S	0.685	1.00
152_S	460_K	0.683	1.00
223_V	229_R	0.682	1.00
67_K	497_W	0.682	1.00
365_Q	369_Q	0.681	1.00
98_F	184_G	0.679	1.00
289_L	478_I	0.679	1.00
8_S	14_G	0.679	1.00
371_L	374_V	0.679	1.00
58_F	184_G	0.675	1.00
338_L	343_Y	0.675	1.00
177_E	181_Y	0.674	1.00
132_I	145_I	0.674	1.00
291_Y	328_P	0.674	1.00
81_V	155_I	0.673	1.00
189_E	206_G	0.673	1.00
257_N	490_S	0.672	1.00
79_Y	155_I	0.672	1.00
98_F	165_M	0.672	1.00
44_Y	116_A	0.672	1.00
240_F	493_L	0.667	1.00
338_L	374_V	0.665	1.00
54_V	199_V	0.665	1.00
209_Q	213_P	0.664	1.00
319_A	461_T	0.664	1.00
110_K	136_E	0.662	1.00
98_F	169_A	0.661	1.00
425_A	445_D	0.661	1.00
80_T	83_D	0.659	1.00
338_L	341_A	0.658	1.00
98_F	104_F	0.657	1.00
425_A	428_N	0.656	1.00
190_L	193_W	0.654	1.00
323_S	465_K	0.653	1.00
14_G	19_L	0.652	1.00
294_N	329_Y	0.652	1.00
113_L	158_L	0.650	1.00
170_A	174_Y	0.649	1.00
11_V	15_I	0.647	1.00
65_L	159_A	0.647	1.00
476_P	479_P	0.647	1.00
65_L	71_L	0.645	1.00
114_D	134_K	0.645	1.00
277_Q	280_F	0.641	1.00
104_F	141_T	0.641	1.00
489_H	496_F	0.639	1.00
449_A	452_L	0.636	1.00
282_N	285_V	0.636	1.00
358_S	362_K	0.636	1.00
135_T	145_I	0.635	1.00
445_D	449_A	0.635	1.00
102_T	108_A	0.634	1.00
117_S	148_K	0.633	1.00
298_L	367_T	0.632	1.00
100_D	170_A	0.632	1.00
412_S	418_W	0.632	1.00
385_A	407_T	0.632	1.00
12_A	15_I	0.629	1.00
8_S	12_A	0.628	1.00
86_I	150_P	0.627	1.00
105_N	141_T	0.627	1.00
275_V	437_A	0.627	1.00
90_V	143_V	0.626	1.00
225_D	228_T	0.625	1.00
203_K	211_G	0.624	1.00
14_G	17_T	0.621	1.00
463_L	467_A	0.620	1.00
233_L	490_S	0.619	1.00
490_S	493_L	0.619	1.00
111_A	115_R	0.618	1.00
92_L	141_T	0.618	1.00
199_V	222_P	0.617	1.00
12_A	16_A	0.616	1.00
174_Y	177_E	0.616	1.00
105_N	168_P	0.615	1.00
98_F	185_T	0.615	1.00
114_D	168_P	0.612	1.00
268_Q	310_A	0.612	1.00
338_L	376_I	0.610	1.00
10_L	13_L	0.606	1.00
71_L	155_I	0.605	1.00
269_R	363_V	0.605	1.00
296_P	299_V	0.604	1.00
21_A	24_A	0.604	1.00
211_G	214_K	0.603	1.00
20_M	23_C	0.603	1.00
457_P	460_K	0.602	1.00
46_A	51_S	0.602	1.00
104_F	112_N	0.601	1.00
363_V	367_T	0.600	1.00
277_Q	401_G	0.600	1.00
282_N	342_G	0.600	1.00
259_E	494_T	0.599	1.00
427_Q	449_A	0.599	1.00
335_R	374_V	0.599	1.00
197_D	221_R	0.599	1.00
371_L	376_I	0.598	1.00
188_Y	203_K	0.597	1.00
19_L	24_A	0.596	1.00
421_S	449_A	0.596	1.00
226_N	229_R	0.596	1.00
215_L	493_L	0.594	1.00
367_T	378_A	0.593	1.00
341_A	344_P	0.593	1.00
62_L	109_V	0.593	1.00
280_F	351_L	0.593	1.00
270_Y	477_W	0.593	1.00
350_T	403_R	0.593	1.00
280_F	285_V	0.592	1.00
59_Y	185_T	0.590	1.00
306_Y	486_V	0.590	1.00
106_A	141_T	0.590	1.00
338_L	342_G	0.589	1.00
39_T	51_S	0.589	1.00
276_T	281_D	0.589	1.00
188_Y	217_S	0.589	1.00
323_S	469_D	0.588	1.00
358_S	361_Q	0.588	1.00
420_L	467_A	0.586	1.00
39_T	48_D	0.586	1.00
8_S	11_V	0.585	1.00
23_C	26_A	0.585	1.00
119_P	122_H	0.585	1.00
52_Q	161_P	0.584	1.00
83_D	87_T	0.583	1.00
9_G	13_L	0.583	1.00
383_M	388_R	0.583	1.00
34_V	220_W	0.582	1.00
174_Y	181_Y	0.581	1.00
59_Y	182_P	0.580	1.00
444_V	447_F	0.580	1.00
204_F	207_Y	0.580	1.00
79_Y	91_K	0.578	1.00
10_L	14_G	0.578	1.00
363_V	481_V	0.577	1.00
347_F	353_S	0.576	1.00
451_A	460_K	0.576	1.00
230_A	248_Q	0.576	1.00
129_Y	163_T	0.576	1.00
378_A	404_M	0.574	1.00
205_A	212_L	0.573	1.00
236_G	490_S	0.570	1.00
149_Q	449_A	0.570	1.00
293_I	480_L	0.568	1.00
61_G	185_T	0.566	1.00
475_S	478_I	0.566	1.00
227_N	248_Q	0.565	1.00
293_I	478_I	0.565	1.00
409_W	423_L	0.564	1.00
343_Y	376_I	0.563	1.00
331_P	338_L	0.563	1.00
290_N	327_W	0.561	1.00
299_V	303_F	0.561	1.00
271_I	480_L	0.561	1.00
273_M	290_N	0.560	1.00
92_L	96_I	0.560	1.00
41_L	199_V	0.560	1.00
441_N	444_V	0.558	1.00
329_Y	370_Q	0.557	1.00
347_F	352_W	0.557	1.00
447_F	451_A	0.555	1.00
85_G	455_N	0.555	1.00
255_N	491_K	0.554	1.00
18_A	23_C	0.554	1.00
285_V	289_L	0.553	1.00
291_Y	334_A	0.553	1.00
244_I	488_A	0.552	1.00
326_P	472_W	0.552	1.00
348_S	352_W	0.552	1.00
221_R	237_E	0.550	1.00
409_W	412_S	0.550	1.00
106_A	139_D	0.549	1.00
343_Y	349_T	0.549	1.00
240_F	489_H	0.548	1.00
455_N	459_E	0.548	1.00
275_V	281_D	0.548	1.00
256_K	491_K	0.548	1.00
473_Q	476_P	0.547	1.00
111_A	169_A	0.547	1.00
454_T	460_K	0.546	1.00
227_N	231_A	0.545	1.00
114_D	137_A	0.544	1.00
182_P	190_L	0.543	1.00
339_K	343_Y	0.542	1.00
321_A	468_Q	0.541	1.00
233_L	238_A	0.541	1.00
353_S	361_Q	0.541	1.00
29_D	200_K	0.539	1.00
41_L	193_W	0.536	1.00
85_G	89_T	0.536	1.00
244_I	249_A	0.536	1.00
364_L	406_Y	0.535	1.00
98_F	167_S	0.535	1.00
330_D	336_E	0.534	1.00
48_D	385_A	0.532	1.00
279_P	403_R	0.532	1.00
389_A	393_E	0.531	1.00
253_E	306_Y	0.531	1.00
468_Q	472_W	0.530	1.00
321_A	325_K	0.530	1.00
249_A	486_V	0.527	1.00
102_T	168_P	0.527	1.00
57_S	220_W	0.526	1.00
87_T	136_E	0.526	1.00
370_Q	374_V	0.526	1.00
302_A	366_F	0.525	1.00
344_P	349_T	0.524	1.00
306_Y	484_K	0.524	1.00
98_F	105_N	0.524	1.00
264_P	308_T	0.523	1.00
214_K	494_T	0.522	1.00
92_L	106_A	0.520	1.00
99_Q	185_T	0.520	1.00
34_V	38_F	0.519	1.00
77_E	92_L	0.518	1.00
98_F	112_N	0.518	1.00
92_L	109_V	0.518	1.00
280_F	404_M	0.518	1.00
385_A	388_R	0.518	1.00
291_Y	330_D	0.518	1.00
103_D	108_A	0.517	1.00
190_L	201_V	0.517	1.00
298_L	480_L	0.516	1.00
270_Y	407_T	0.516	1.00
296_P	328_P	0.516	1.00
64_G	209_Q	0.516	1.00
249_A	260_L	0.516	1.00
271_I	478_I	0.516	1.00
73_N	78_S	0.516	1.00
31_V	238_A	0.516	1.00
61_G	90_V	0.515	1.00
287_E	327_W	0.515	1.00
324_Y	469_D	0.514	1.00
104_F	109_V	0.513	1.00
322_Q	465_K	0.512	1.00
60_Q	209_Q	0.512	1.00
166_I	171_L	0.508	1.00
115_R	171_L	0.508	1.00
311_T	326_P	0.508	1.00
104_F	108_A	0.507	1.00
280_F	403_R	0.507	1.00
306_Y	309_P	0.506	1.00
240_F	487_S	0.506	1.00
269_R	481_V	0.506	1.00
411_A	419_A	0.505	1.00
389_A	392_V	0.505	1.00
352_W	391_E	0.505	1.00
388_R	392_V	0.503	1.00
333_K	340_E	0.502	1.00
63_F	159_A	0.502	1.00
297_A	366_F	0.502	1.00
487_S	496_F	0.502	1.00
269_R	483_E	0.501	1.00
360_A	406_Y	0.501	1.00
55_A	59_Y	0.501	1.00
338_L	347_F	0.501	1.00
298_L	302_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4qflA	1	0.9336	100	0.109	Contact Map
1uqwA	1	0.9512	100	0.117	Contact Map
4fajA	1	0.9141	100	0.137	Contact Map
3zs6A	1	0.9336	100	0.139	Contact Map
4tozA	1	0.9473	100	0.141	Contact Map
4gl8A	1	0.9238	100	0.142	Contact Map
3m8uA	1	0.9336	100	0.142	Contact Map
1dpeA	1	0.9336	100	0.144	Contact Map
3tpaA	1	0.9316	100	0.144	Contact Map
1xocA	2	0.9336	100	0.146	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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