OPGE - ECOLI - GREMLIN Contacts

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OPGE - Phosphoethanolamine transferase OpgE

UniProt:	P75785	Sequences: MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTAAFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQAYGAPNFNTLLALHSTNMEESTEILTIFPWYSYLVGLFIFALGVIAIRRKKENEKARWNTFDSLCLVFSVATFFVAPVQNLAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQTYVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVDGKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADKNTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLYTMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVPFMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNFQLQKVDYNHLGTDIFDPKP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13321
Length:	527 (468)
Sequences:	5687 (4833)
Seq/√Len:	223.4

ECOLI - OPGE YHBX EPTC EPTA EPTB YEJM YJGX
BACSU - LTAS1 YQGS LTAS2 YVGJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
244_F	402_R	5.807	1.00
254_A	465_K	5.326	1.00
479_Q	493_P	4.547	1.00
290_N	318_R	4.022	1.00
350_A	411_S	3.829	1.00
244_F	247_S	3.725	1.00
346_A	407_Q	3.419	1.00
27_S	31_N	3.342	1.00
240_D	246_S	3.324	1.00
402_R	406_D	3.188	1.00
295_Q	355_Q	3.017	1.00
406_D	409_R	2.975	1.00
220_V	417_L	2.883	1.00
222_V	419_Y	2.880	1.00
468_R	494_F	2.866	1.00
224_G	227_A	2.785	1.00
320_D	323_Y	2.760	1.00
219_Y	289_A	2.759	1.00
217_Q	414_S	2.699	1.00
31_N	34_L	2.650	1.00
476_F	495_I	2.634	1.00
256_Y	468_R	2.624	1.00
218_T	415_F	2.551	1.00
219_Y	481_T	2.472	1.00
289_A	481_T	2.365	1.00
233_G	242_T	2.359	1.00
405_Y	417_L	2.310	1.00
124_V	128_R	2.260	1.00
218_T	357_Q	2.213	1.00
23_Y	27_S	2.201	1.00
242_T	246_S	2.182	1.00
455_S	458_D	2.179	1.00
408_L	417_L	2.171	1.00
249_N	409_R	2.142	1.00
235_F	252_I	2.128	1.00
24_F	27_S	2.126	1.00
221_V	358_L	2.114	1.00
31_N	35_G	2.111	1.00
272_N	284_N	2.087	1.00
222_V	401_L	2.046	1.00
345_T	361_L	2.004	1.00
344_M	347_Q	1.993	1.00
348_V	351_Q	1.986	1.00
305_I	308_Y	1.985	1.00
406_D	410_N	1.978	1.00
26_Q	31_N	1.963	1.00
403_K	406_D	1.956	1.00
275_V	278_K	1.952	1.00
220_V	415_F	1.926	1.00
416_S	453_V	1.866	1.00
339_E	403_K	1.843	1.00
215_K	414_S	1.842	1.00
342_L	346_A	1.815	1.00
375_Q	396_Q	1.778	1.00
263_T	362_H	1.775	1.00
380_T	395_T	1.752	1.00
221_V	418_V	1.740	1.00
27_S	30_I	1.711	1.00
270_T	420_F	1.711	1.00
23_Y	26_Q	1.709	1.00
254_A	463_V	1.704	1.00
338_D	342_L	1.694	1.00
366_S	393_T	1.694	1.00
243_P	398_D	1.691	1.00
367_H	422_D	1.680	1.00
140_T	143_S	1.676	1.00
376_G	379_E	1.676	1.00
26_Q	29_L	1.676	1.00
175_P	178_R	1.669	1.00
263_T	267_L	1.652	1.00
245_A	401_L	1.629	1.00
420_F	470_A	1.627	1.00
233_G	240_D	1.618	1.00
23_Y	31_N	1.599	1.00
126_A	130_K	1.597	1.00
299_F	348_V	1.588	1.00
20_T	26_Q	1.576	1.00
346_A	411_S	1.569	1.00
444_Q	447_F	1.559	1.00
217_Q	416_S	1.556	1.00
227_A	394_M	1.524	1.00
250_G	254_A	1.523	1.00
399_D	403_K	1.522	1.00
149_S	152_T	1.510	1.00
407_Q	411_S	1.500	1.00
26_Q	30_I	1.500	1.00
288_L	478_S	1.497	1.00
395_T	399_D	1.489	1.00
407_Q	410_N	1.485	1.00
30_I	34_L	1.479	1.00
224_G	397_T	1.469	1.00
227_A	397_T	1.459	1.00
233_G	246_S	1.448	1.00
418_V	453_V	1.444	1.00
223_I	267_L	1.434	1.00
346_A	350_A	1.433	1.00
308_Y	311_A	1.429	1.00
219_Y	416_S	1.424	1.00
41_L	45_A	1.411	1.00
218_T	413_S	1.410	1.00
342_L	363_L	1.404	1.00
170_K	174_Y	1.402	1.00
26_Q	33_G	1.399	1.00
244_F	405_Y	1.393	1.00
339_E	396_Q	1.388	1.00
436_Y	439_H	1.386	1.00
404_L	417_L	1.380	1.00
256_Y	451_F	1.376	1.00
174_Y	178_R	1.372	1.00
399_D	402_R	1.370	1.00
250_G	454_I	1.367	1.00
28_L	32_L	1.363	1.00
231_A	391_L	1.361	1.00
30_I	33_G	1.360	1.00
239_W	391_L	1.353	1.00
279_P	283_D	1.348	1.00
224_G	419_Y	1.346	1.00
347_Q	351_Q	1.336	1.00
444_Q	448_Q	1.334	1.00
403_K	407_Q	1.324	1.00
98_M	104_I	1.318	1.00
156_A	163_W	1.313	1.00
19_W	26_Q	1.312	1.00
178_R	181_K	1.298	1.00
18_P	26_Q	1.294	1.00
248_V	402_R	1.294	1.00
26_Q	34_L	1.282	1.00
196_R	199_K	1.277	1.00
227_A	232_L	1.277	1.00
158_V	162_A	1.275	1.00
273_R	475_G	1.273	1.00
378_Y	399_D	1.267	1.00
219_Y	358_L	1.258	1.00
28_L	31_N	1.256	1.00
125_I	129_R	1.255	1.00
137_R	140_T	1.254	1.00
242_T	245_A	1.253	1.00
197_M	200_L	1.252	1.00
173_G	176_V	1.239	1.00
25_L	29_L	1.239	1.00
27_S	34_L	1.238	1.00
310_T	313_A	1.234	1.00
342_L	404_L	1.225	1.00
244_F	398_D	1.217	1.00
451_F	473_F	1.215	1.00
244_F	248_V	1.214	1.00
366_S	394_M	1.213	1.00
421_S	449_V	1.212	1.00
171_D	174_Y	1.212	1.00
223_I	420_F	1.200	1.00
39_S	43_T	1.199	1.00
294_F	356_P	1.198	1.00
19_W	27_S	1.198	1.00
221_V	270_T	1.197	1.00
285_F	477_F	1.193	1.00
123_G	127_I	1.191	1.00
297_W	357_Q	1.189	1.00
99_E	103_E	1.185	1.00
268_G	274_V	1.184	1.00
400_L	403_K	1.180	1.00
350_A	407_Q	1.178	1.00
341_L	361_L	1.177	1.00
303_G	309_D	1.172	1.00
174_Y	177_F	1.169	1.00
229_R	448_Q	1.163	1.00
247_S	402_R	1.159	1.00
265_K	269_L	1.158	1.00
159_Q	163_W	1.157	1.00
307_E	310_T	1.151	1.00
309_D	313_A	1.150	1.00
306_G	311_A	1.150	1.00
39_S	45_A	1.148	1.00
248_V	405_Y	1.147	1.00
442_K	446_N	1.143	1.00
100_E	103_E	1.138	1.00
44_A	48_A	1.135	1.00
227_A	231_A	1.134	1.00
300_S	308_Y	1.129	1.00
154_F	157_P	1.129	1.00
343_D	403_K	1.128	1.00
299_F	359_I	1.128	1.00
178_R	183_V	1.127	1.00
45_A	49_I	1.127	1.00
227_A	245_A	1.122	1.00
231_A	394_M	1.119	1.00
181_K	185_V	1.112	1.00
227_A	242_T	1.112	1.00
416_S	455_S	1.111	1.00
20_T	27_S	1.109	1.00
101_S	104_I	1.108	1.00
224_G	401_L	1.106	1.00
155_V	159_Q	1.105	1.00
221_V	360_V	1.104	1.00
19_W	23_Y	1.103	1.00
263_T	367_H	1.102	1.00
263_T	268_G	1.097	1.00
114_L	118_F	1.097	1.00
121_A	125_I	1.095	1.00
349_L	408_L	1.093	1.00
375_Q	378_Y	1.092	1.00
103_E	107_I	1.087	1.00
311_A	315_I	1.084	1.00
19_W	24_F	1.082	1.00
251_L	464_I	1.082	1.00
157_P	160_N	1.081	1.00
298_W	362_H	1.081	1.00
400_L	404_L	1.076	1.00
297_W	359_I	1.074	1.00
157_P	164_G	1.073	1.00
228_R	424_G	1.073	1.00
29_L	33_G	1.070	1.00
405_Y	409_R	1.068	1.00
443_Y	446_N	1.067	1.00
255_D	448_Q	1.066	1.00
305_I	312_I	1.065	1.00
194_Q	198_A	1.063	1.00
170_K	173_G	1.057	1.00
157_P	161_L	1.056	1.00
196_R	200_L	1.055	1.00
308_Y	312_I	1.055	1.00
61_Q	65_V	1.053	1.00
160_N	163_W	1.052	1.00
248_V	409_R	1.052	1.00
253_F	451_F	1.047	1.00
425_L	431_G	1.047	1.00
147_V	151_A	1.047	1.00
243_P	248_V	1.045	1.00
244_F	399_D	1.042	1.00
24_F	31_N	1.041	1.00
112_S	115_V	1.039	1.00
304_Q	309_D	1.036	1.00
36_Y	39_S	1.032	1.00
344_M	348_V	1.032	1.00
223_I	360_V	1.031	1.00
183_V	186_N	1.031	1.00
161_L	165_G	1.026	1.00
366_S	397_T	1.026	1.00
292_A	483_I	1.025	1.00
181_K	184_I	1.019	1.00
309_D	312_I	1.011	1.00
217_Q	356_P	1.008	1.00
219_Y	294_F	1.005	1.00
265_K	268_G	1.003	1.00
201_S	204_K	1.000	1.00
374_T	379_E	0.998	1.00
157_P	162_A	0.998	1.00
100_E	104_I	0.998	1.00
178_R	182_D	0.995	1.00
193_E	196_R	0.993	1.00
39_S	42_Y	0.993	1.00
20_T	24_F	0.992	1.00
220_V	357_Q	0.992	1.00
192_E	200_L	0.988	1.00
23_Y	28_L	0.987	1.00
223_I	270_T	0.981	1.00
420_F	473_F	0.980	1.00
21_A	26_Q	0.975	1.00
161_L	164_G	0.975	1.00
319_A	322_V	0.973	1.00
177_F	181_K	0.969	1.00
251_L	495_I	0.965	1.00
255_D	467_R	0.965	1.00
26_Q	35_G	0.961	1.00
478_S	483_I	0.958	1.00
347_Q	350_A	0.958	1.00
159_Q	162_A	0.956	1.00
27_S	33_G	0.956	1.00
219_Y	418_V	0.955	1.00
229_R	235_F	0.952	1.00
216_Y	292_A	0.951	1.00
24_F	28_L	0.947	1.00
297_W	348_V	0.945	1.00
416_S	477_F	0.945	1.00
263_T	422_D	0.944	1.00
207_W	210_T	0.942	1.00
361_L	404_L	0.942	1.00
225_E	422_D	0.941	1.00
32_L	35_G	0.940	1.00
21_A	25_L	0.936	1.00
191_I	197_M	0.933	1.00
160_N	165_G	0.931	1.00
475_G	491_K	0.931	1.00
142_D	153_F	0.928	1.00
18_P	28_L	0.928	1.00
270_T	473_F	0.924	1.00
198_A	201_S	0.922	1.00
16_F	23_Y	0.921	0.99
186_N	190_V	0.919	0.99
418_V	477_F	0.917	0.99
371_C	389_C	0.913	0.99
335_N	364_M	0.905	0.99
122_L	126_A	0.905	0.99
23_Y	30_I	0.903	0.99
160_N	164_G	0.896	0.99
228_R	231_A	0.896	0.99
374_T	392_Y	0.895	0.99
156_A	165_G	0.895	0.99
110_W	114_L	0.893	0.99
298_W	312_I	0.890	0.99
136_A	139_N	0.887	0.99
179_F	182_D	0.886	0.99
317_K	360_V	0.885	0.99
441_D	444_Q	0.884	0.99
340_A	343_D	0.883	0.99
259_A	469_S	0.883	0.99
136_A	142_D	0.881	0.99
289_A	478_S	0.879	0.99
342_L	397_T	0.874	0.99
158_V	161_L	0.871	0.99
39_S	52_L	0.871	0.99
250_G	452_M	0.871	0.99
343_D	407_Q	0.870	0.99
176_V	185_V	0.868	0.99
426_A	429_E	0.866	0.99
183_V	187_N	0.863	0.99
30_I	35_G	0.862	0.99
286_V	317_K	0.861	0.99
161_L	166_V	0.860	0.99
306_G	309_D	0.857	0.99
405_Y	419_Y	0.857	0.99
248_V	452_M	0.856	0.99
303_G	320_D	0.853	0.99
192_E	196_R	0.852	0.99
306_G	312_I	0.852	0.99
268_G	272_N	0.852	0.99
180_A	184_I	0.850	0.99
289_A	358_L	0.848	0.99
365_G	396_Q	0.846	0.99
150_V	153_F	0.845	0.99
401_L	419_Y	0.844	0.99
228_R	234_A	0.841	0.99
195_E	198_A	0.839	0.99
266_S	269_L	0.839	0.99
168_K	172_T	0.834	0.99
225_E	367_H	0.833	0.99
99_E	102_T	0.831	0.99
55_R	58_P	0.829	0.99
345_T	359_I	0.829	0.99
265_K	273_R	0.827	0.99
419_Y	452_M	0.825	0.99
237_G	391_L	0.822	0.99
176_V	180_A	0.820	0.99
20_T	30_I	0.820	0.99
196_R	201_S	0.820	0.99
219_Y	477_F	0.815	0.99
374_T	378_Y	0.814	0.99
198_A	202_G	0.814	0.99
103_E	106_T	0.812	0.99
221_V	473_F	0.811	0.99
89_T	92_A	0.809	0.99
311_A	314_S	0.808	0.99
96_T	100_E	0.806	0.99
152_T	155_V	0.806	0.99
158_V	163_W	0.805	0.99
370_A	425_L	0.805	0.99
345_T	349_L	0.799	0.99
163_W	166_V	0.797	0.99
178_R	184_I	0.794	0.99
162_A	165_G	0.792	0.98
363_L	397_T	0.792	0.98
479_Q	496_S	0.789	0.98
185_V	188_N	0.789	0.98
382_V	385_K	0.789	0.98
100_E	107_I	0.783	0.98
153_F	157_P	0.783	0.98
319_A	324_F	0.779	0.98
221_V	420_F	0.778	0.98
28_L	35_G	0.778	0.98
425_L	428_K	0.778	0.98
23_Y	34_L	0.777	0.98
80_Q	112_S	0.775	0.98
156_A	161_L	0.774	0.98
263_T	273_R	0.773	0.98
182_D	185_V	0.773	0.98
27_S	32_L	0.773	0.98
259_A	269_L	0.772	0.98
390_Y	394_M	0.772	0.98
195_E	199_K	0.771	0.98
25_L	31_N	0.771	0.98
17_S	21_A	0.771	0.98
156_A	164_G	0.769	0.98
420_F	449_V	0.769	0.98
117_L	121_A	0.769	0.98
381_F	392_Y	0.767	0.98
224_G	342_L	0.767	0.98
138_W	141_F	0.766	0.98
413_S	456_S	0.764	0.98
381_F	395_T	0.763	0.98
216_Y	356_P	0.763	0.98
43_T	46_F	0.762	0.98
388_S	392_Y	0.761	0.98
294_F	481_T	0.760	0.98
493_P	496_S	0.760	0.98
175_P	179_F	0.759	0.98
138_W	142_D	0.759	0.98
172_T	175_P	0.758	0.98
192_E	197_M	0.757	0.98
18_P	23_Y	0.757	0.98
66_G	70_L	0.757	0.98
40_L	44_A	0.757	0.98
227_A	419_Y	0.757	0.98
174_Y	179_F	0.755	0.98
124_V	127_I	0.754	0.98
157_P	165_G	0.752	0.98
271_L	358_L	0.751	0.98
307_E	314_S	0.750	0.98
48_A	52_L	0.750	0.98
154_F	158_V	0.750	0.98
304_Q	308_Y	0.749	0.98
220_V	404_L	0.749	0.98
339_E	399_D	0.747	0.98
193_E	200_L	0.747	0.98
349_L	359_I	0.746	0.98
257_I	448_Q	0.745	0.98
248_V	401_L	0.745	0.98
264_Q	268_G	0.745	0.98
22_F	26_Q	0.745	0.98
191_I	196_R	0.745	0.98
408_L	412_G	0.744	0.98
158_V	166_V	0.744	0.98
312_I	317_K	0.744	0.98
280_Q	283_D	0.742	0.98
146_L	150_V	0.741	0.98
222_V	342_L	0.741	0.98
241_N	391_L	0.738	0.98
21_A	27_S	0.736	0.98
59_R	63_V	0.736	0.98
223_I	362_H	0.735	0.98
179_F	185_V	0.734	0.98
42_Y	45_A	0.733	0.97
245_A	452_M	0.733	0.97
28_L	33_G	0.730	0.97
17_S	24_F	0.728	0.97
263_T	269_L	0.726	0.97
218_T	416_S	0.724	0.97
26_Q	32_L	0.724	0.97
345_T	404_L	0.723	0.97
230_D	445_Q	0.723	0.97
23_Y	33_G	0.722	0.97
98_M	101_S	0.721	0.97
17_S	20_T	0.721	0.97
310_T	314_S	0.721	0.97
197_M	201_S	0.720	0.97
46_F	50_L	0.718	0.97
308_Y	313_A	0.716	0.97
401_L	417_L	0.714	0.97
156_A	160_N	0.714	0.97
343_D	346_A	0.713	0.97
143_S	146_L	0.709	0.97
227_A	366_S	0.709	0.97
199_K	202_G	0.709	0.97
337_K	340_A	0.708	0.97
111_Y	115_V	0.708	0.97
174_Y	183_V	0.708	0.97
16_F	26_Q	0.706	0.97
264_Q	267_L	0.706	0.97
449_V	470_A	0.705	0.97
177_F	180_A	0.703	0.97
139_N	142_D	0.698	0.97
363_L	400_L	0.697	0.97
16_F	27_S	0.697	0.97
392_Y	395_T	0.695	0.97
285_F	474_L	0.695	0.97
268_G	273_R	0.694	0.97
365_G	393_T	0.694	0.97
286_V	296_T	0.691	0.96
451_F	468_R	0.691	0.96
338_D	341_L	0.691	0.96
367_H	423_H	0.689	0.96
308_Y	315_I	0.687	0.96
413_S	457_D	0.686	0.96
297_W	300_S	0.685	0.96
40_L	48_A	0.683	0.96
186_N	189_E	0.683	0.96
443_Y	447_F	0.682	0.96
440_D	443_Y	0.680	0.96
160_N	166_V	0.680	0.96
221_V	285_F	0.679	0.96
298_W	302_Q	0.678	0.96
20_T	23_Y	0.677	0.96
24_F	35_G	0.676	0.96
178_R	186_N	0.674	0.96
175_P	185_V	0.672	0.96
293_G	356_P	0.667	0.96
339_E	343_D	0.666	0.96
126_A	129_R	0.664	0.96
233_G	241_N	0.663	0.95
396_Q	399_D	0.662	0.95
342_L	400_L	0.661	0.95
28_L	34_L	0.660	0.95
311_A	316_A	0.660	0.95
172_T	176_V	0.660	0.95
427_F	430_R	0.659	0.95
98_M	102_T	0.659	0.95
305_I	310_T	0.659	0.95
243_P	246_S	0.651	0.95
319_A	323_Y	0.651	0.95
120_F	124_V	0.648	0.95
39_S	44_A	0.646	0.95
18_P	27_S	0.646	0.95
287_T	291_R	0.645	0.95
175_P	182_D	0.645	0.95
168_K	174_Y	0.641	0.95
19_W	31_N	0.640	0.95
141_F	145_C	0.639	0.95
301_N	336_T	0.639	0.95
244_F	406_D	0.638	0.94
27_S	35_G	0.637	0.94
179_F	183_V	0.637	0.94
181_K	186_N	0.635	0.94
358_L	477_F	0.633	0.94
222_V	417_L	0.631	0.94
113_Y	117_L	0.631	0.94
142_D	148_F	0.631	0.94
101_S	105_L	0.629	0.94
251_L	462_R	0.629	0.94
96_T	104_I	0.626	0.94
112_S	116_G	0.626	0.94
91_L	95_S	0.624	0.94
346_A	403_K	0.623	0.94
153_F	156_A	0.622	0.94
463_V	466_A	0.622	0.94
411_S	415_F	0.622	0.94
46_F	53_L	0.622	0.94
326_K	331_E	0.622	0.94
75_Y	85_P	0.621	0.94
273_R	474_L	0.621	0.94
23_Y	32_L	0.621	0.94
170_K	175_P	0.620	0.94
254_A	258_A	0.620	0.94
347_Q	407_Q	0.617	0.93
113_Y	128_R	0.616	0.93
304_Q	307_E	0.616	0.93
305_I	309_D	0.615	0.93
218_T	411_S	0.615	0.93
301_N	364_M	0.613	0.93
155_V	161_L	0.613	0.93
155_V	158_V	0.612	0.93
18_P	31_N	0.611	0.93
192_E	204_K	0.611	0.93
61_Q	64_L	0.611	0.93
179_F	186_N	0.610	0.93
158_V	165_G	0.610	0.93
179_F	184_I	0.608	0.93
261_G	427_F	0.608	0.93
200_L	204_K	0.607	0.93
240_D	395_T	0.605	0.93
220_V	349_L	0.604	0.93
168_K	175_P	0.604	0.93
200_L	203_M	0.604	0.93
254_A	464_I	0.604	0.93
116_G	120_F	0.604	0.93
149_S	153_F	0.603	0.93
288_L	291_R	0.603	0.93
170_K	178_R	0.601	0.93
286_V	358_L	0.600	0.92
272_N	311_A	0.600	0.92
182_D	186_N	0.597	0.92
374_T	381_F	0.597	0.92
445_Q	448_Q	0.597	0.92
19_W	29_L	0.596	0.92
426_A	446_N	0.596	0.92
242_T	398_D	0.595	0.92
210_T	495_I	0.595	0.92
250_G	257_I	0.594	0.92
450_P	453_V	0.594	0.92
43_T	47_T	0.593	0.92
298_W	301_N	0.591	0.92
62_K	65_V	0.591	0.92
397_T	400_L	0.591	0.92
159_Q	166_V	0.590	0.92
45_A	51_L	0.589	0.92
148_F	152_T	0.588	0.92
20_T	25_L	0.587	0.92
99_E	104_I	0.586	0.92
217_Q	294_F	0.585	0.92
25_L	33_G	0.584	0.91
194_Q	201_S	0.584	0.91
128_R	131_K	0.584	0.91
271_L	360_V	0.583	0.91
147_V	157_P	0.582	0.91
169_L	172_T	0.581	0.91
167_F	170_K	0.580	0.91
253_F	257_I	0.579	0.91
50_L	53_L	0.579	0.91
39_S	48_A	0.578	0.91
19_W	22_F	0.578	0.91
385_K	389_C	0.577	0.91
232_L	235_F	0.576	0.91
143_S	147_V	0.575	0.91
313_A	316_A	0.574	0.91
266_S	470_A	0.573	0.91
441_D	445_Q	0.573	0.91
151_A	155_V	0.573	0.91
88_N	91_L	0.572	0.91
264_Q	269_L	0.571	0.91
184_I	187_N	0.571	0.91
199_K	203_M	0.571	0.91
328_G	331_E	0.570	0.90
263_T	423_H	0.570	0.90
426_A	431_G	0.570	0.90
92_A	95_S	0.569	0.90
290_N	296_T	0.569	0.90
307_E	316_A	0.568	0.90
225_E	366_S	0.568	0.90
41_L	49_I	0.567	0.90
249_N	254_A	0.567	0.90
225_E	363_L	0.563	0.90
228_R	390_Y	0.563	0.90
16_F	31_N	0.563	0.90
307_E	312_I	0.562	0.90
261_G	266_S	0.561	0.90
474_L	478_S	0.561	0.90
430_R	445_Q	0.559	0.90
309_D	314_S	0.559	0.90
155_V	160_N	0.559	0.90
106_T	109_P	0.558	0.90
25_L	28_L	0.557	0.89
307_E	311_A	0.557	0.89
306_G	316_A	0.557	0.89
62_K	66_G	0.556	0.89
86_N	89_T	0.556	0.89
70_L	74_C	0.556	0.89
179_F	187_N	0.556	0.89
195_E	201_S	0.555	0.89
38_F	48_A	0.554	0.89
20_T	31_N	0.553	0.89
48_A	51_L	0.552	0.89
136_A	140_T	0.552	0.89
269_L	274_V	0.552	0.89
208_T	211_A	0.551	0.89
441_D	446_N	0.551	0.89
211_A	214_P	0.550	0.89
19_W	34_L	0.550	0.89
374_T	393_T	0.550	0.89
104_I	107_I	0.549	0.89
171_D	175_P	0.549	0.89
133_N	140_T	0.549	0.89
127_I	131_K	0.548	0.89
217_Q	455_S	0.548	0.89
38_F	51_L	0.547	0.89
279_P	282_Q	0.547	0.89
264_Q	306_G	0.547	0.89
111_Y	114_L	0.545	0.88
18_P	25_L	0.545	0.88
169_L	173_G	0.544	0.88
236_G	391_L	0.544	0.88
21_A	31_N	0.543	0.88
173_G	179_F	0.543	0.88
152_T	156_A	0.543	0.88
300_S	362_H	0.542	0.88
123_G	126_A	0.542	0.88
23_Y	29_L	0.541	0.88
37_P	41_L	0.539	0.88
224_G	366_S	0.536	0.88
159_Q	164_G	0.536	0.88
174_Y	182_D	0.536	0.88
269_L	363_L	0.536	0.88
38_F	42_Y	0.535	0.87
378_Y	381_F	0.534	0.87
39_S	47_T	0.534	0.87
341_L	400_L	0.533	0.87
272_N	275_V	0.532	0.87
39_S	50_L	0.532	0.87
22_F	27_S	0.530	0.87
36_Y	53_L	0.530	0.87
173_G	177_F	0.530	0.87
178_R	185_V	0.528	0.87
155_V	165_G	0.528	0.87
458_D	462_R	0.525	0.87
47_T	51_L	0.525	0.87
127_I	130_K	0.524	0.86
340_A	344_M	0.523	0.86
226_S	421_S	0.522	0.86
17_S	31_N	0.522	0.86
425_L	429_E	0.522	0.86
314_S	317_K	0.521	0.86
302_Q	362_H	0.520	0.86
252_I	463_V	0.520	0.86
134_E	137_R	0.520	0.86
176_V	179_F	0.520	0.86
305_I	311_A	0.519	0.86
157_P	166_V	0.518	0.86
184_I	188_N	0.518	0.86
312_I	316_A	0.516	0.86
162_A	166_V	0.516	0.86
171_D	176_V	0.515	0.85
222_V	404_L	0.514	0.85
233_G	236_G	0.512	0.85
258_A	424_G	0.512	0.85
326_K	329_N	0.510	0.85
36_Y	41_L	0.509	0.85
191_I	203_M	0.508	0.85
267_L	271_L	0.508	0.85
135_K	139_N	0.508	0.85
327_E	331_E	0.507	0.85
390_Y	424_G	0.507	0.85
205_D	208_T	0.506	0.84
21_A	62_K	0.506	0.84
232_L	363_L	0.503	0.84
179_F	188_N	0.500	0.84
220_V	345_T	0.500	0.84

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4uorA	3	0.6262	100	0.529	Contact Map
2w5qA	1	0.6281	100	0.533	Contact Map
2w8dA	1	0.63	100	0.534	Contact Map
3lxqA	1	0.6129	100	0.538	Contact Map
4kavA	1	0.5636	100	0.541	Contact Map
4upkA	3	0.5806	100	0.547	Contact Map
4tn0A	1	0.5332	100	0.547	Contact Map
2vqrA	3	0.5787	100	0.548	Contact Map
4uphA	2	0.5769	100	0.551	Contact Map
4upiA	2	0.5787	100	0.552	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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