YBIO - ECOLI - GREMLIN Contacts

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YBIO - Moderate conductance mechanosensitive channel YbiO

UniProt:	P75783	Sequences: MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQKKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCALPLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAVLRLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIGYGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFDFWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGATPAEPLPPGEPTL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13320
Length:	741 (669)
Sequences:	1651 (1263)
Seq/√Len:	48.8

ECOLI - YBIO MSCM MSCK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
633_V	642_A	5.895	1.00
640_D	706_K	5.614	1.00
632_D	679_A	4.924	1.00
641_K	711_A	4.593	1.00
642_A	682_L	4.556	1.00
719_T	723_L	4.414	1.00
707_H	711_A	4.297	1.00
644_Q	648_D	4.255	1.00
461_Q	464_V	4.165	1.00
557_T	560_K	4.018	1.00
632_D	635_R	3.895	1.00
706_K	710_L	3.894	1.00
107_G	110_L	3.860	1.00
632_D	717_V	3.699	1.00
642_A	646_L	3.641	1.00
645_A	707_H	3.541	1.00
50_G	53_A	3.415	1.00
650_V	684_V	3.312	1.00
635_R	678_T	3.137	1.00
677_N	681_T	3.136	1.00
635_R	715_A	3.047	1.00
50_G	54_D	3.036	1.00
387_A	438_A	2.957	1.00
632_D	678_T	2.943	1.00
635_R	717_V	2.935	1.00
632_D	676_S	2.868	1.00
674_G	681_T	2.760	1.00
380_S	446_W	2.759	1.00
656_N	699_A	2.675	1.00
32_S	35_E	2.653	1.00
638_D	641_K	2.622	1.00
634_D	714_R	2.563	1.00
103_S	106_Y	2.542	1.00
39_E	43_E	2.529	1.00
705_K	709_D	2.513	1.00
640_D	643_N	2.476	1.00
635_R	676_S	2.449	1.00
95_V	102_V	2.441	1.00
676_S	681_T	2.414	1.00
635_R	675_L	2.380	1.00
636_H	705_K	2.364	1.00
48_A	52_L	2.363	1.00
49_Y	53_A	2.344	1.00
590_E	600_R	2.330	1.00
46_K	50_G	2.323	1.00
678_T	715_A	2.322	1.00
551_I	559_V	2.299	1.00
649_A	707_H	2.292	1.00
641_K	644_Q	2.275	1.00
39_E	42_I	2.240	1.00
703_Q	707_H	2.225	1.00
99_V	103_S	2.195	1.00
477_S	525_T	2.187	1.00
673_V	683_R	2.179	1.00
632_D	715_A	2.169	1.00
51_A	54_D	2.169	1.00
37_A	40_P	2.155	1.00
678_T	717_V	2.149	1.00
703_Q	706_K	2.111	1.00
599_V	609_I	2.107	1.00
110_L	113_R	2.107	1.00
643_N	647_K	2.069	1.00
53_A	57_D	2.056	1.00
81_V	86_P	2.055	1.00
581_T	586_T	2.046	1.00
648_D	707_H	2.027	1.00
632_D	681_T	2.025	1.00
679_A	715_A	2.015	1.00
579_L	602_D	2.011	1.00
676_S	717_V	2.002	1.00
488_I	492_L	1.998	0.99
63_K	67_D	1.983	0.99
643_N	702_S	1.976	0.99
449_F	453_N	1.926	0.99
648_D	652_E	1.920	0.99
672_I	680_F	1.919	0.99
29_T	33_T	1.896	0.99
635_R	677_N	1.883	0.99
662_L	692_K	1.866	0.99
62_R	65_L	1.849	0.99
37_A	42_I	1.846	0.99
626_S	685_S	1.844	0.99
110_L	120_N	1.839	0.99
52_L	55_V	1.837	0.99
41_D	45_K	1.834	0.99
632_D	675_L	1.831	0.99
252_R	261_A	1.829	0.99
679_A	716_P	1.821	0.99
45_K	48_A	1.815	0.99
631_Y	675_L	1.791	0.99
604_G	687_T	1.787	0.99
94_T	102_V	1.783	0.99
96_L	99_V	1.779	0.99
641_K	645_A	1.769	0.99
542_A	545_G	1.769	0.99
677_N	720_Y	1.768	0.99
54_D	57_D	1.735	0.99
629_A	684_V	1.731	0.99
646_L	684_V	1.730	0.99
34_T	39_E	1.726	0.98
644_Q	651_A	1.717	0.98
45_K	54_D	1.710	0.98
249_A	258_D	1.697	0.98
678_T	719_T	1.691	0.98
35_E	39_E	1.687	0.98
39_E	51_A	1.683	0.98
557_T	612_S	1.675	0.98
96_L	104_R	1.648	0.98
679_A	717_V	1.641	0.98
454_W	457_N	1.638	0.98
454_W	460_G	1.627	0.98
61_S	69_L	1.624	0.98
455_L	458_G	1.617	0.98
634_D	717_V	1.613	0.98
579_L	586_T	1.612	0.98
721_Q	725_A	1.612	0.98
636_H	714_R	1.604	0.98
64_E	68_Q	1.598	0.97
69_L	73_A	1.597	0.97
110_L	124_S	1.595	0.97
631_Y	704_V	1.591	0.97
645_A	711_A	1.591	0.97
101_E	105_H	1.585	0.97
649_A	708_F	1.575	0.97
632_D	719_T	1.569	0.97
451_F	458_G	1.564	0.97
44_Q	47_A	1.557	0.97
447_G	454_W	1.554	0.97
50_G	57_D	1.551	0.97
45_K	52_L	1.551	0.97
558_L	564_T	1.549	0.97
635_R	679_A	1.546	0.97
676_S	680_F	1.539	0.97
53_A	59_D	1.516	0.97
62_R	66_I	1.500	0.96
360_F	364_F	1.496	0.96
543_G	548_G	1.494	0.96
686_F	700_L	1.492	0.96
724_P	727_G	1.492	0.96
546_A	555_S	1.486	0.96
668_N	685_S	1.481	0.96
42_I	46_K	1.469	0.96
100_T	106_Y	1.459	0.96
307_T	355_F	1.449	0.96
156_R	159_A	1.446	0.95
685_S	694_W	1.444	0.95
100_T	104_R	1.441	0.95
678_T	681_T	1.439	0.95
448_L	451_F	1.438	0.95
608_I	627_V	1.437	0.95
471_A	652_E	1.435	0.95
41_D	54_D	1.435	0.95
601_Q	605_A	1.430	0.95
98_K	101_E	1.426	0.95
646_L	704_V	1.419	0.95
716_P	720_Y	1.415	0.95
714_R	717_V	1.407	0.95
573_G	596_S	1.389	0.94
707_H	710_L	1.387	0.94
647_K	651_A	1.385	0.94
562_I	567_F	1.378	0.94
591_R	598_G	1.373	0.94
675_L	701_D	1.368	0.94
66_I	69_L	1.368	0.94
184_P	187_I	1.364	0.94
542_A	557_T	1.362	0.94
45_K	49_Y	1.359	0.94
677_N	718_Q	1.358	0.94
161_P	165_K	1.355	0.94
458_G	461_Q	1.350	0.93
81_V	88_T	1.349	0.93
46_K	49_Y	1.344	0.93
450_D	454_W	1.334	0.93
35_E	41_D	1.331	0.93
598_G	606_Y	1.328	0.93
671_G	694_W	1.323	0.93
522_S	526_I	1.322	0.93
31_D	35_E	1.319	0.93
678_T	718_Q	1.311	0.92
39_E	53_A	1.311	0.92
697_R	701_D	1.310	0.92
307_T	359_F	1.309	0.92
48_A	51_A	1.308	0.92
575_N	598_G	1.305	0.92
550_A	611_W	1.305	0.92
42_I	45_K	1.303	0.92
449_F	452_W	1.302	0.92
66_I	70_R	1.301	0.92
537_I	557_T	1.301	0.92
29_T	35_E	1.298	0.92
29_T	32_S	1.297	0.92
48_A	55_V	1.297	0.92
676_S	679_A	1.295	0.92
39_E	46_K	1.291	0.92
455_L	460_G	1.285	0.92
98_K	104_R	1.277	0.91
52_L	57_D	1.275	0.91
95_V	103_S	1.274	0.91
223_Q	226_F	1.273	0.91
456_Q	460_G	1.272	0.91
639_A	706_K	1.266	0.91
87_P	90_V	1.263	0.91
45_K	50_G	1.261	0.91
110_L	117_L	1.259	0.91
35_E	38_P	1.251	0.90
719_T	725_A	1.251	0.90
30_T	34_T	1.249	0.90
45_K	53_A	1.242	0.90
670_A	684_V	1.240	0.90
676_S	715_A	1.238	0.90
451_F	460_G	1.237	0.90
450_D	453_N	1.231	0.90
142_S	152_Y	1.225	0.90
44_Q	48_A	1.225	0.90
585_L	607_H	1.221	0.89
60_T	64_E	1.220	0.89
152_Y	156_R	1.220	0.89
636_H	675_L	1.217	0.89
61_S	64_E	1.217	0.89
449_F	460_G	1.213	0.89
581_T	620_F	1.211	0.89
452_W	455_L	1.211	0.89
44_Q	53_A	1.210	0.89
551_I	555_S	1.209	0.89
68_Q	71_T	1.208	0.89
456_Q	461_Q	1.206	0.89
383_I	438_A	1.205	0.89
452_W	458_G	1.201	0.89
120_N	123_G	1.199	0.89
61_S	66_I	1.197	0.88
600_R	623_G	1.196	0.88
51_A	58_N	1.191	0.88
546_A	571_E	1.190	0.88
580_V	614_I	1.190	0.88
96_L	106_Y	1.186	0.88
708_F	713_V	1.186	0.88
34_T	40_P	1.186	0.88
347_W	351_A	1.183	0.88
48_A	53_A	1.182	0.88
454_W	462_K	1.180	0.88
723_L	726_P	1.179	0.88
627_V	697_R	1.172	0.87
454_W	458_G	1.171	0.87
636_H	639_A	1.168	0.87
639_A	702_S	1.163	0.87
628_V	685_S	1.161	0.87
37_A	46_K	1.160	0.87
721_Q	724_P	1.159	0.87
96_L	103_S	1.153	0.86
98_K	105_H	1.152	0.86
636_H	680_F	1.148	0.86
38_P	43_E	1.146	0.86
40_P	43_E	1.144	0.86
582_I	617_F	1.143	0.86
45_K	56_L	1.132	0.85
677_N	717_V	1.131	0.85
667_P	684_V	1.130	0.85
33_T	38_P	1.129	0.85
42_I	50_G	1.129	0.85
436_C	684_V	1.124	0.85
652_E	703_Q	1.122	0.85
715_A	719_T	1.122	0.85
46_K	53_A	1.115	0.85
43_E	47_A	1.114	0.85
41_D	46_K	1.113	0.84
43_E	46_K	1.112	0.84
53_A	68_Q	1.111	0.84
194_D	197_L	1.110	0.84
550_A	555_S	1.109	0.84
649_A	703_Q	1.107	0.84
244_F	264_W	1.105	0.84
99_V	106_Y	1.094	0.83
630_N	681_T	1.090	0.83
128_P	131_P	1.090	0.83
74_A	77_P	1.088	0.83
689_L	692_K	1.084	0.83
37_A	41_D	1.077	0.82
592_M	596_S	1.077	0.82
542_A	560_K	1.076	0.82
467_L	471_A	1.076	0.82
159_A	162_L	1.076	0.82
52_L	56_L	1.076	0.82
632_D	677_N	1.072	0.82
558_L	567_F	1.068	0.82
539_P	542_A	1.065	0.82
664_I	667_P	1.065	0.82
549_L	552_S	1.058	0.81
602_D	685_S	1.057	0.81
505_R	604_G	1.056	0.81
46_K	51_A	1.052	0.81
101_E	106_Y	1.051	0.81
102_V	105_H	1.050	0.81
662_L	696_V	1.045	0.80
561_D	611_W	1.044	0.80
47_A	53_A	1.043	0.80
675_L	680_F	1.043	0.80
546_A	573_G	1.043	0.80
549_L	568_I	1.039	0.80
161_P	164_R	1.037	0.80
48_A	114_F	1.029	0.79
550_A	561_D	1.027	0.79
60_T	63_K	1.026	0.79
447_G	451_F	1.025	0.79
546_A	611_W	1.024	0.79
646_L	650_V	1.023	0.79
454_W	464_V	1.022	0.79
671_G	695_T	1.020	0.79
415_L	418_R	1.017	0.79
585_L	621_V	1.015	0.79
648_D	711_A	1.015	0.79
451_F	454_W	1.014	0.78
650_V	663_I	1.014	0.78
100_T	103_S	1.012	0.78
81_V	85_V	1.010	0.78
652_E	707_H	1.009	0.78
628_V	683_R	1.009	0.78
505_R	508_T	1.008	0.78
47_A	51_A	1.007	0.78
94_T	97_Q	1.007	0.78
100_T	107_G	1.006	0.78
451_F	455_L	0.998	0.77
73_A	76_P	0.997	0.77
555_S	561_D	0.994	0.77
131_P	134_F	0.992	0.77
560_K	612_S	0.991	0.77
601_Q	607_H	0.990	0.77
98_K	102_V	0.989	0.77
32_S	46_K	0.986	0.76
537_I	542_A	0.986	0.76
536_N	548_G	0.984	0.76
94_T	98_K	0.982	0.76
635_R	714_R	0.981	0.76
252_R	258_D	0.981	0.76
400_K	403_T	0.979	0.76
508_T	512_L	0.979	0.76
34_T	46_K	0.975	0.76
543_G	546_A	0.973	0.76
67_D	71_T	0.973	0.76
626_S	668_N	0.971	0.75
603_T	628_V	0.970	0.75
47_A	54_D	0.970	0.75
449_F	455_L	0.969	0.75
41_D	44_Q	0.969	0.75
38_P	52_L	0.966	0.75
52_L	59_D	0.964	0.75
717_V	721_Q	0.963	0.75
73_A	77_P	0.963	0.75
542_A	555_S	0.960	0.75
44_Q	710_L	0.960	0.75
547_L	608_I	0.960	0.75
633_V	708_F	0.959	0.74
640_D	644_Q	0.957	0.74
147_L	158_C	0.955	0.74
30_T	33_T	0.955	0.74
627_V	686_F	0.954	0.74
152_Y	159_A	0.954	0.74
545_G	560_K	0.951	0.74
579_L	599_V	0.948	0.74
30_T	36_P	0.947	0.74
433_L	437_V	0.946	0.73
595_R	610_P	0.945	0.73
545_G	612_S	0.945	0.73
159_A	163_Y	0.940	0.73
194_D	241_R	0.937	0.73
33_T	37_A	0.933	0.72
70_R	78_A	0.933	0.72
636_H	650_V	0.932	0.72
551_I	613_S	0.929	0.72
226_F	377_T	0.928	0.72
54_D	58_N	0.927	0.72
705_K	708_F	0.927	0.72
634_D	678_T	0.926	0.72
96_L	101_E	0.925	0.72
714_R	725_A	0.925	0.72
53_A	56_L	0.924	0.72
39_E	49_Y	0.919	0.71
39_E	52_L	0.916	0.71
31_D	34_T	0.914	0.71
44_Q	60_T	0.912	0.71
548_G	567_F	0.912	0.71
366_P	569_Q	0.911	0.71
451_F	456_Q	0.910	0.70
530_L	688_T	0.908	0.70
62_R	76_P	0.905	0.70
83_K	87_P	0.905	0.70
31_D	37_A	0.901	0.70
198_L	201_T	0.900	0.70
602_D	650_V	0.900	0.70
671_G	698_F	0.899	0.70
596_S	668_N	0.897	0.69
568_I	572_N	0.897	0.69
37_A	43_E	0.894	0.69
41_D	47_A	0.888	0.69
133_T	360_F	0.886	0.68
515_N	562_I	0.883	0.68
639_A	705_K	0.881	0.68
39_E	58_N	0.879	0.68
680_F	705_K	0.874	0.67
56_L	59_D	0.873	0.67
384_I	580_V	0.871	0.67
632_D	721_Q	0.869	0.67
245_C	252_R	0.868	0.67
97_Q	100_T	0.867	0.67
507_R	669_F	0.865	0.67
239_V	271_L	0.863	0.66
472_L	475_F	0.862	0.66
634_D	637_E	0.862	0.66
717_V	723_L	0.859	0.66
53_A	58_N	0.859	0.66
96_L	102_V	0.859	0.66
121_I	524_I	0.858	0.66
85_V	89_L	0.857	0.66
114_F	524_I	0.856	0.66
573_G	608_I	0.856	0.66
601_Q	701_D	0.855	0.66
679_A	719_T	0.855	0.66
607_H	618_A	0.854	0.66
390_V	609_I	0.854	0.66
573_G	668_N	0.852	0.65
485_A	537_I	0.851	0.65
311_L	315_F	0.851	0.65
94_T	99_V	0.850	0.65
562_I	599_V	0.849	0.65
448_L	454_W	0.849	0.65
546_A	550_A	0.849	0.65
35_E	45_K	0.846	0.65
606_Y	620_F	0.845	0.65
83_K	86_P	0.842	0.64
49_Y	52_L	0.841	0.64
92_E	102_V	0.841	0.64
35_E	44_Q	0.838	0.64
149_F	308_V	0.837	0.64
311_L	352_S	0.837	0.64
546_A	599_V	0.835	0.64
715_A	723_L	0.834	0.64
58_N	70_R	0.833	0.64
107_G	124_S	0.833	0.64
109_A	113_R	0.832	0.64
633_V	676_S	0.831	0.63
82_P	88_T	0.830	0.63
525_T	620_F	0.830	0.63
451_F	461_Q	0.829	0.63
605_A	612_S	0.829	0.63
635_R	721_Q	0.827	0.63
308_V	311_L	0.827	0.63
99_V	104_R	0.826	0.63
114_F	118_Y	0.823	0.63
399_A	402_I	0.822	0.63
575_N	687_T	0.821	0.62
39_E	44_Q	0.821	0.62
58_N	436_C	0.820	0.62
519_V	611_W	0.820	0.62
35_E	46_K	0.819	0.62
572_N	611_W	0.818	0.62
165_K	313_L	0.815	0.62
38_P	48_A	0.814	0.62
114_F	305_C	0.814	0.62
546_A	563_I	0.813	0.62
613_S	616_T	0.812	0.62
722_V	727_G	0.811	0.62
458_G	462_K	0.810	0.61
568_I	600_R	0.810	0.61
537_I	541_L	0.809	0.61
541_L	597_V	0.807	0.61
673_V	684_V	0.807	0.61
536_N	539_P	0.806	0.61
93_Q	96_L	0.805	0.61
508_T	572_N	0.805	0.61
554_G	610_P	0.804	0.61
543_G	560_K	0.803	0.61
543_G	550_A	0.798	0.60
511_T	606_Y	0.798	0.60
545_G	551_I	0.797	0.60
49_Y	55_V	0.795	0.60
34_T	38_P	0.794	0.60
599_V	627_V	0.794	0.60
93_Q	149_F	0.793	0.60
717_V	725_A	0.792	0.60
550_A	668_N	0.792	0.60
568_I	601_Q	0.792	0.60
33_T	36_P	0.791	0.60
96_L	100_T	0.789	0.59
63_K	71_T	0.787	0.59
383_I	445_A	0.786	0.59
34_T	45_K	0.786	0.59
630_N	674_G	0.786	0.59
510_L	604_G	0.786	0.59
542_A	614_I	0.785	0.59
164_R	167_G	0.782	0.59
672_I	675_L	0.780	0.59
208_L	256_I	0.780	0.59
32_S	52_L	0.779	0.58
154_L	157_L	0.779	0.58
49_Y	59_D	0.778	0.58
98_K	106_Y	0.778	0.58
611_W	667_P	0.776	0.58
506_T	510_L	0.775	0.58
94_T	103_S	0.774	0.58
586_T	602_D	0.773	0.58
541_L	601_Q	0.773	0.58
675_L	717_V	0.773	0.58
568_I	578_D	0.772	0.58
32_S	39_E	0.772	0.58
97_Q	103_S	0.772	0.58
554_G	595_R	0.771	0.58
294_I	298_A	0.771	0.58
35_E	48_A	0.769	0.57
35_E	42_I	0.769	0.57
36_P	46_K	0.769	0.57
519_V	626_S	0.768	0.57
229_A	276_G	0.767	0.57
36_P	40_P	0.766	0.57
149_F	153_W	0.766	0.57
603_T	609_I	0.764	0.57
188_I	222_Q	0.764	0.57
639_A	682_L	0.764	0.57
508_T	539_P	0.761	0.57
43_E	52_L	0.761	0.57
450_D	455_L	0.760	0.57
32_S	36_P	0.760	0.57
678_T	723_L	0.758	0.56
84_I	88_T	0.756	0.56
40_P	46_K	0.756	0.56
477_S	481_W	0.756	0.56
545_G	605_A	0.756	0.56
37_A	45_K	0.755	0.56
636_H	676_S	0.755	0.56
546_A	561_D	0.754	0.56
578_D	670_A	0.754	0.56
47_A	50_G	0.753	0.56
650_V	686_F	0.753	0.56
199_A	305_C	0.751	0.56
31_D	48_A	0.751	0.56
640_D	702_S	0.750	0.56
181_L	253_P	0.748	0.55
537_I	545_G	0.747	0.55
611_W	698_F	0.745	0.55
82_P	85_V	0.744	0.55
699_A	702_S	0.744	0.55
422_W	425_A	0.743	0.55
541_L	550_A	0.742	0.55
636_H	709_D	0.742	0.55
347_W	445_A	0.741	0.55
574_M	603_T	0.741	0.55
84_I	87_P	0.738	0.54
189_G	193_I	0.738	0.54
405_S	408_T	0.738	0.54
133_T	308_V	0.737	0.54
464_V	722_V	0.737	0.54
34_T	43_E	0.737	0.54
117_L	120_N	0.736	0.54
373_M	425_A	0.736	0.54
30_T	357_V	0.735	0.54
650_V	700_L	0.735	0.54
568_I	690_P	0.734	0.54
670_A	685_S	0.733	0.54
387_A	434_T	0.733	0.54
43_E	50_G	0.732	0.54
32_S	38_P	0.731	0.54
611_W	668_N	0.731	0.54
542_A	601_Q	0.729	0.53
563_I	649_A	0.728	0.53
47_A	55_V	0.728	0.53
42_I	59_D	0.727	0.53
577_G	638_D	0.727	0.53
426_A	429_T	0.726	0.53
550_A	572_N	0.726	0.53
541_L	545_G	0.725	0.53
36_P	60_T	0.725	0.53
37_A	44_Q	0.724	0.53
646_L	670_A	0.722	0.53
95_V	109_A	0.722	0.53
573_G	667_P	0.722	0.53
46_K	55_V	0.722	0.53
650_V	685_S	0.721	0.53
149_F	158_C	0.721	0.53
550_A	597_V	0.721	0.53
672_I	719_T	0.721	0.53
632_D	714_R	0.720	0.53
678_T	720_Y	0.719	0.52
251_L	261_A	0.719	0.52
239_V	527_M	0.718	0.52
160_L	430_A	0.718	0.52
44_Q	55_V	0.718	0.52
672_I	705_K	0.718	0.52
564_T	668_N	0.718	0.52
537_I	560_K	0.717	0.52
154_L	206_Q	0.716	0.52
322_T	657_E	0.714	0.52
477_S	521_I	0.713	0.52
240_L	265_S	0.711	0.52
534_G	556_Q	0.710	0.51
107_G	111_S	0.709	0.51
300_V	594_I	0.709	0.51
601_Q	685_S	0.707	0.51
525_T	571_E	0.706	0.51
680_F	715_A	0.706	0.51
93_Q	97_Q	0.705	0.51
672_I	676_S	0.703	0.51
573_G	592_M	0.701	0.51
134_F	137_A	0.700	0.50
94_T	106_Y	0.700	0.50
43_E	54_D	0.697	0.50
632_D	637_E	0.696	0.50
679_A	721_Q	0.696	0.50
32_S	43_E	0.696	0.50
39_E	121_I	0.696	0.50
344_A	348_H	0.695	0.50
578_D	601_Q	0.695	0.50
100_T	105_H	0.695	0.50
550_A	567_F	0.694	0.50
463_T	474_L	0.690	0.49
563_I	618_A	0.690	0.49
541_L	557_T	0.690	0.49
620_F	626_S	0.689	0.49
149_F	152_Y	0.689	0.49
271_L	275_I	0.689	0.49
88_T	92_E	0.688	0.49
380_S	384_I	0.688	0.49
447_G	450_D	0.687	0.49
41_D	55_V	0.686	0.49
38_P	42_I	0.685	0.49
234_E	238_A	0.685	0.49
637_E	642_A	0.684	0.49
505_R	539_P	0.684	0.49
561_D	597_V	0.681	0.49
66_I	73_A	0.680	0.48
634_D	639_A	0.680	0.48
63_K	360_F	0.678	0.48
588_T	690_P	0.677	0.48
550_A	607_H	0.677	0.48
656_N	662_L	0.677	0.48
40_P	50_G	0.676	0.48
533_I	563_I	0.676	0.48
512_L	573_G	0.676	0.48
678_T	721_Q	0.675	0.48
505_R	514_R	0.674	0.48
649_A	699_A	0.674	0.48
62_R	73_A	0.674	0.48
495_D	620_F	0.673	0.48
112_A	121_I	0.672	0.48
39_E	45_K	0.672	0.48
598_G	614_I	0.672	0.48
581_T	601_Q	0.670	0.47
642_A	711_A	0.670	0.47
395_S	431_R	0.669	0.47
516_A	562_I	0.665	0.47
62_R	75_T	0.664	0.47
546_A	549_L	0.663	0.47
119_R	360_F	0.663	0.47
567_F	611_W	0.662	0.47
449_F	454_W	0.662	0.47
677_N	719_T	0.661	0.47
476_F	480_G	0.661	0.47
300_V	303_M	0.660	0.46
46_K	57_D	0.659	0.46
555_S	611_W	0.659	0.46
48_A	54_D	0.658	0.46
551_I	563_I	0.658	0.46
71_T	76_P	0.658	0.46
568_I	574_M	0.658	0.46
99_V	105_H	0.657	0.46
572_N	626_S	0.657	0.46
43_E	89_L	0.657	0.46
115_G	118_Y	0.656	0.46
365_D	611_W	0.655	0.46
663_I	682_L	0.654	0.46
535_V	639_A	0.654	0.46
511_T	572_N	0.654	0.46
512_L	598_G	0.653	0.46
54_D	91_E	0.653	0.46
272_S	276_G	0.653	0.46
649_A	700_L	0.651	0.46
510_L	594_I	0.651	0.46
505_R	509_L	0.648	0.45
485_A	518_A	0.647	0.45
35_E	47_A	0.647	0.45
639_A	680_F	0.647	0.45
47_A	87_P	0.646	0.45
671_G	683_R	0.646	0.45
179_N	182_Q	0.645	0.45
244_F	250_E	0.643	0.45
575_N	606_Y	0.643	0.45
510_L	572_N	0.642	0.45
240_L	311_L	0.640	0.44
64_E	70_R	0.640	0.44
435_V	439_V	0.638	0.44
575_N	579_L	0.638	0.44
30_T	40_P	0.637	0.44
545_G	602_D	0.637	0.44
393_M	584_P	0.634	0.44
635_R	720_Y	0.631	0.44
442_L	637_E	0.630	0.43
723_L	727_G	0.630	0.43
62_R	69_L	0.629	0.43
74_A	158_C	0.628	0.43
111_S	121_I	0.627	0.43
597_V	611_W	0.626	0.43
534_G	554_G	0.626	0.43
46_K	52_L	0.625	0.43
240_L	244_F	0.625	0.43
715_A	720_Y	0.625	0.43
585_L	616_T	0.625	0.43
567_F	663_I	0.624	0.43
65_L	72_V	0.624	0.43
33_T	44_Q	0.624	0.43
640_D	699_A	0.622	0.43
232_L	722_V	0.622	0.43
637_E	672_I	0.622	0.43
107_G	120_N	0.622	0.43
136_N	468_I	0.620	0.42
639_A	713_V	0.620	0.42
104_R	108_E	0.620	0.42
207_V	211_N	0.620	0.42
600_R	604_G	0.620	0.42
541_L	590_E	0.619	0.42
547_L	555_S	0.618	0.42
550_A	698_F	0.617	0.42
546_A	564_T	0.615	0.42
480_G	647_K	0.614	0.42
357_V	360_F	0.614	0.42
637_E	675_L	0.614	0.42
127_K	130_N	0.614	0.42
575_N	628_V	0.614	0.42
512_L	627_V	0.613	0.42
68_Q	78_A	0.613	0.42
43_E	59_D	0.612	0.42
153_W	203_F	0.610	0.41
48_A	58_N	0.610	0.41
530_L	535_V	0.610	0.41
567_F	698_F	0.608	0.41
99_V	102_V	0.607	0.41
564_T	567_F	0.607	0.41
211_N	535_V	0.606	0.41
42_I	52_L	0.605	0.41
305_C	315_F	0.605	0.41
111_S	115_G	0.605	0.41
29_T	37_A	0.604	0.41
547_L	667_P	0.604	0.41
33_T	42_I	0.604	0.41
623_G	677_N	0.604	0.41
31_D	42_I	0.603	0.41
244_F	378_V	0.603	0.41
351_A	447_G	0.602	0.41
508_T	604_G	0.601	0.41
57_D	146_V	0.601	0.41
205_G	208_L	0.601	0.41
301_I	696_V	0.600	0.40
95_V	104_R	0.600	0.40
558_L	568_I	0.600	0.40
667_P	670_A	0.600	0.40
197_L	201_T	0.600	0.40
546_A	567_F	0.600	0.40
36_P	45_K	0.600	0.40
683_R	694_W	0.599	0.40
536_N	570_F	0.599	0.40
449_F	456_Q	0.598	0.40
117_L	121_I	0.598	0.40
537_I	543_G	0.598	0.40
506_T	621_V	0.598	0.40
524_I	528_I	0.597	0.40
40_P	47_A	0.597	0.40
34_T	44_Q	0.597	0.40
57_D	70_R	0.596	0.40
455_L	716_P	0.596	0.40
539_P	544_A	0.594	0.40
300_V	551_I	0.594	0.40
366_P	548_G	0.594	0.40
33_T	52_L	0.594	0.40
542_A	596_S	0.594	0.40
460_G	463_T	0.592	0.40
72_V	75_T	0.592	0.40
505_R	543_G	0.592	0.40
40_P	48_A	0.592	0.40
69_L	72_V	0.592	0.40
539_P	543_G	0.591	0.40
30_T	39_E	0.591	0.40
92_E	150_G	0.591	0.40
576_T	596_S	0.590	0.39
61_S	70_R	0.590	0.39
200_L	204_V	0.588	0.39
674_G	679_A	0.588	0.39
240_L	268_L	0.587	0.39
40_P	44_Q	0.586	0.39
310_A	355_F	0.586	0.39
468_I	551_I	0.586	0.39
156_R	161_P	0.586	0.39
231_A	235_F	0.585	0.39
82_P	89_L	0.585	0.39
95_V	98_K	0.585	0.39
542_A	690_P	0.585	0.39
583_G	675_L	0.584	0.39
545_G	557_T	0.583	0.39
42_I	49_Y	0.583	0.39
556_Q	638_D	0.582	0.39
518_A	579_L	0.582	0.39
420_N	438_A	0.582	0.39
625_G	688_T	0.581	0.39
472_L	728_A	0.580	0.39
550_A	578_D	0.580	0.39
601_Q	628_V	0.579	0.38
453_N	456_Q	0.579	0.38
256_I	429_T	0.579	0.38
179_N	293_Q	0.579	0.38
62_R	84_I	0.578	0.38
543_G	561_D	0.577	0.38
307_T	310_A	0.576	0.38
36_P	39_E	0.575	0.38
369_S	396_R	0.575	0.38
644_Q	647_K	0.575	0.38
355_F	358_L	0.574	0.38
672_I	694_W	0.574	0.38
380_S	483_V	0.574	0.38
637_E	719_T	0.573	0.38
617_F	672_I	0.573	0.38
90_V	99_V	0.572	0.38
40_P	72_V	0.571	0.38
624_I	687_T	0.571	0.38
236_F	245_C	0.571	0.38
508_T	550_A	0.571	0.38
108_E	112_A	0.571	0.38
42_I	55_V	0.570	0.38
578_D	626_S	0.569	0.37
636_H	715_A	0.569	0.37
147_L	154_L	0.569	0.37
202_L	227_L	0.568	0.37
52_L	58_N	0.568	0.37
539_P	580_V	0.566	0.37
442_L	609_I	0.565	0.37
561_D	698_F	0.565	0.37
34_T	42_I	0.565	0.37
79_E	90_V	0.565	0.37
567_F	668_N	0.564	0.37
567_F	597_V	0.564	0.37
37_A	60_T	0.563	0.37
650_V	672_I	0.563	0.37
32_S	45_K	0.563	0.37
35_E	52_L	0.563	0.37
548_G	690_P	0.562	0.37
60_T	645_A	0.562	0.37
470_I	533_I	0.562	0.37
41_D	53_A	0.561	0.37
571_E	578_D	0.561	0.37
722_V	726_P	0.561	0.37
561_D	572_N	0.561	0.37
38_P	47_A	0.560	0.37
203_F	207_V	0.560	0.37
389_F	442_L	0.559	0.37
86_P	89_L	0.559	0.37
33_T	47_A	0.558	0.36
461_Q	465_D	0.558	0.36
78_A	84_I	0.557	0.36
689_L	710_L	0.557	0.36
516_A	551_I	0.556	0.36
233_I	238_A	0.556	0.36
574_M	597_V	0.556	0.36
649_A	665_G	0.555	0.36
245_C	280_I	0.555	0.36
547_L	597_V	0.554	0.36
180_W	184_P	0.554	0.36
600_R	622_R	0.554	0.36
548_G	590_E	0.554	0.36
555_S	558_L	0.554	0.36
656_N	703_Q	0.554	0.36
220_A	224_S	0.554	0.36
508_T	561_D	0.554	0.36
351_A	389_F	0.553	0.36
575_N	586_T	0.553	0.36
632_D	636_H	0.553	0.36
365_D	552_S	0.553	0.36
230_F	280_I	0.553	0.36
515_N	566_V	0.553	0.36
554_G	564_T	0.552	0.36
561_D	607_H	0.552	0.36
114_F	147_L	0.552	0.36
561_D	567_F	0.552	0.36
29_T	34_T	0.552	0.36
253_P	596_S	0.552	0.36
51_A	57_D	0.552	0.36
40_P	53_A	0.551	0.36
605_A	620_F	0.550	0.36
555_S	567_F	0.549	0.36
521_I	588_T	0.549	0.36
575_N	592_M	0.549	0.36
34_T	47_A	0.548	0.36
46_K	59_D	0.548	0.36
632_D	723_L	0.547	0.35
605_A	625_G	0.547	0.35
43_E	53_A	0.546	0.35
34_T	37_A	0.546	0.35
578_D	668_N	0.546	0.35
450_D	458_G	0.545	0.35
46_K	54_D	0.545	0.35
601_Q	626_S	0.544	0.35
63_K	66_I	0.544	0.35
561_D	687_T	0.543	0.35
150_G	196_L	0.543	0.35
611_W	626_S	0.542	0.35
481_W	508_T	0.541	0.35
508_T	580_V	0.541	0.35
626_S	667_P	0.541	0.35
59_D	63_K	0.541	0.35
51_A	55_V	0.540	0.35
43_E	49_Y	0.539	0.35
505_R	510_L	0.539	0.35
564_T	575_N	0.539	0.35
580_V	695_T	0.538	0.35
573_G	611_W	0.538	0.35
560_K	605_A	0.537	0.34
49_Y	403_T	0.537	0.34
542_A	567_F	0.537	0.34
35_E	305_C	0.536	0.34
232_L	268_L	0.536	0.34
49_Y	56_L	0.536	0.34
345_L	471_A	0.536	0.34
91_E	106_Y	0.536	0.34
366_P	573_G	0.536	0.34
277_Y	397_W	0.535	0.34
548_G	558_L	0.534	0.34
572_N	597_V	0.533	0.34
488_I	493_A	0.533	0.34
311_L	631_Y	0.533	0.34
126_H	188_I	0.532	0.34
222_Q	254_F	0.532	0.34
32_S	58_N	0.531	0.34
634_D	719_T	0.531	0.34
673_V	681_T	0.530	0.34
219_I	236_F	0.530	0.34
508_T	519_V	0.530	0.34
539_P	558_L	0.530	0.34
85_V	92_E	0.529	0.34
519_V	550_A	0.529	0.34
457_N	462_K	0.529	0.34
677_N	715_A	0.528	0.34
666_E	713_V	0.528	0.34
568_I	571_E	0.528	0.34
547_L	550_A	0.527	0.34
162_L	165_K	0.527	0.34
127_K	133_T	0.527	0.34
675_L	705_K	0.526	0.33
488_I	526_I	0.526	0.33
437_V	441_L	0.525	0.33
512_L	572_N	0.525	0.33
611_W	670_A	0.524	0.33
313_L	317_N	0.524	0.33
94_T	100_T	0.523	0.33
481_W	518_A	0.523	0.33
70_R	580_V	0.523	0.33
166_M	310_A	0.523	0.33
92_E	96_L	0.522	0.33
140_H	192_I	0.521	0.33
42_I	51_A	0.520	0.33
534_G	595_R	0.520	0.33
36_P	47_A	0.520	0.33
365_D	573_G	0.520	0.33
51_A	56_L	0.519	0.33
82_P	87_P	0.519	0.33
568_I	646_L	0.518	0.33
578_D	602_D	0.518	0.33
113_R	118_Y	0.517	0.33
236_F	513_F	0.517	0.33
125_P	712_G	0.516	0.33
308_V	312_Y	0.516	0.33
303_M	362_S	0.516	0.33
646_L	685_S	0.516	0.33
54_D	261_A	0.515	0.33
647_K	702_S	0.515	0.33
578_D	611_W	0.515	0.33
550_A	670_A	0.515	0.33
625_G	687_T	0.514	0.32
550_A	667_P	0.514	0.32
538_A	542_A	0.513	0.32
447_G	452_W	0.512	0.32
719_T	724_P	0.512	0.32
75_T	82_P	0.512	0.32
543_G	698_F	0.511	0.32
31_D	38_P	0.510	0.32
572_N	602_D	0.510	0.32
686_F	698_F	0.510	0.32
81_V	89_L	0.509	0.32
88_T	118_Y	0.509	0.32
484_L	517_L	0.508	0.32
31_D	43_E	0.508	0.32
130_N	138_L	0.507	0.32
718_Q	723_L	0.507	0.32
613_S	694_W	0.507	0.32
53_A	65_L	0.507	0.32
33_T	54_D	0.507	0.32
602_D	701_D	0.506	0.32
166_M	172_Q	0.506	0.32
45_K	468_I	0.504	0.32
550_A	558_L	0.503	0.31
225_L	674_G	0.503	0.31
146_V	255_T	0.502	0.31
312_Y	316_R	0.502	0.31
394_F	492_L	0.502	0.31
157_L	161_P	0.502	0.31
674_G	701_D	0.502	0.31
543_G	590_E	0.501	0.31
688_T	694_W	0.501	0.31
44_Q	57_D	0.501	0.31
518_A	521_I	0.500	0.31
493_A	508_T	0.500	0.31
580_V	586_T	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3udcA	3	0.3576	100	0.604	Contact Map
5ajiA	3	0.3495	100	0.614	Contact Map
4hw9A	3	0.3347	100	0.629	Contact Map
3j1zP	8	0.3981	74.1	0.972	Contact Map
3h90A	3	0.3806	59.1	0.975	Contact Map
1nz9A	1	0.0648	44	0.977	Contact Map
2kogA	1	0.1538	35.6	0.978	Contact Map
3wdoA	1	0.1188	30.1	0.979	Contact Map
4bgnA	3	0.0553	23.9	0.98	Contact Map
2e6zA	1	0.0688	23.1	0.98	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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