GREMLIN Database
YBGP - Uncharacterized fimbrial chaperone YbgP
UniProt: P75749 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13312
Length: 242 (216)
Sequences: 2862 (2149)
Seq/√Len: 146.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
174_T193_M3.2891.00
57_I135_L3.1781.00
172_Y195_A3.1071.00
166_K199_T2.9191.00
32_N35_D2.9051.00
101_R197_F2.8991.00
195_A198_S2.8701.00
104_L193_M2.8461.00
24_P133_I2.8281.00
155_Q166_K2.7081.00
97_L105_F2.6781.00
164_T201_N2.6121.00
29_I38_T2.5311.00
164_T199_T2.4811.00
51_Y111_E2.4691.00
159_Q164_T2.4651.00
156_V165_L2.4531.00
136_F193_M2.4501.00
29_I88_V2.3831.00
29_I107_Y2.3681.00
34_N140_A2.3611.00
218_D224_R2.2851.00
165_L202_T2.2571.00
47_D81_K2.2051.00
136_F172_Y2.1551.00
58_E132_R2.1301.00
56_W108_N2.0811.00
50_P79_E2.0751.00
157_S164_T2.0541.00
110_R130_Q1.8811.00
32_N38_T1.8801.00
150_V173_L1.8521.00
50_P77_R1.7891.00
69_L88_V1.7891.00
98_P103_T1.7831.00
55_S86_V1.7231.00
154_L165_L1.7141.00
150_V216_Y1.7061.00
142_L171_Y1.6981.00
104_L136_F1.6661.00
58_E108_N1.6551.00
71_A86_V1.6481.00
108_N132_R1.6471.00
154_L173_L1.6321.00
79_E82_A1.6241.00
145_K148_E1.6111.00
24_P109_M1.5921.00
153_Q169_T1.5741.00
57_I67_A1.5721.00
40_L107_Y1.5631.00
162_Q201_N1.5471.00
173_L216_Y1.5111.00
154_L175_I1.5051.00
177_Y215_G1.4781.00
33_A99_G1.4491.00
90_K95_T1.4281.00
144_K148_E1.4171.00
31_F38_T1.4171.00
218_D222_A1.4111.00
53_A76_Q1.4071.00
24_P40_L1.3721.00
69_L135_L1.3611.00
194_V200_V1.3501.00
37_A87_R1.3311.00
157_S166_K1.3231.00
98_P101_R1.3191.00
156_V214_L1.3161.00
29_I133_I1.2781.00
41_R83_T1.2681.00
42_I78_L1.2561.00
174_T216_Y1.2501.00
90_K137_W1.2081.00
46_S111_E1.2051.00
179_G213_Y1.2011.00
104_L174_T1.1951.00
156_V178_L1.1861.00
148_E152_L1.1771.00
181_N185_V1.1591.00
170_A197_F1.1541.00
33_A140_A1.1541.00
88_V135_L1.1511.00
23_Q26_R1.1441.00
56_W132_R1.1430.99
107_Y135_L1.1400.99
22_V78_L1.1280.99
176_A223_L1.1180.99
8_P11_L1.1110.99
26_R40_L1.1110.99
58_E62_G1.0980.99
151_E173_L1.0980.99
116_P124_I1.0920.99
151_E214_L1.0900.99
116_P126_Q1.0850.99
163_L204_T1.0840.99
71_A88_V1.0830.99
175_I194_V1.0740.99
59_N65_S1.0640.99
106_F132_R1.0540.99
59_N63_E1.0530.99
90_K96_Q1.0470.99
33_A137_W1.0430.99
21_A111_E1.0410.99
216_Y224_R1.0410.99
86_V107_Y1.0270.99
56_W110_R1.0250.99
31_F89_V1.0160.99
25_D41_R1.0060.99
144_K171_Y1.0040.99
43_E83_T1.0000.99
86_V109_M0.9810.98
22_V53_A0.9660.98
175_I216_Y0.9650.98
76_Q84_S0.9620.98
216_Y226_T0.9330.98
111_E129_I0.9320.98
46_S51_Y0.9280.98
134_K217_M0.9270.98
46_S49_L0.9270.98
182_E185_V0.9240.98
148_E153_Q0.9220.98
58_E106_F0.9200.98
28_R138_R0.9180.98
24_P42_I0.9170.98
159_Q201_N0.9090.97
153_Q168_P0.9080.97
97_L101_R0.9050.97
31_F69_L0.9030.97
42_I53_A0.8850.97
57_I71_A0.8730.97
100_D197_F0.8720.97
215_G225_M0.8670.97
166_K197_F0.8670.97
71_A107_Y0.8610.96
128_A156_V0.8580.96
84_S110_R0.8540.96
172_Y196_P0.8520.96
9_L12_L0.8490.96
55_S71_A0.8470.96
106_F110_R0.8420.96
206_S209_G0.8360.96
76_Q86_V0.8290.96
25_D83_T0.8260.96
159_Q162_Q0.8250.96
179_G183_K0.8180.95
104_L172_Y0.8180.95
78_L83_T0.8180.95
215_G223_L0.8120.95
108_N130_Q0.8030.95
31_F90_K0.7970.95
176_A217_M0.7940.94
6_G9_L0.7930.94
163_L178_L0.7860.94
175_I222_A0.7840.94
10_M15_S0.7800.94
100_D138_R0.7790.94
92_A95_T0.7740.94
54_Y110_R0.7690.93
162_Q203_N0.7680.93
29_I40_L0.7660.93
15_S19_N0.7650.93
28_R134_K0.7600.93
41_R75_I0.7580.93
109_M133_I0.7570.93
26_R29_I0.7560.93
84_S111_E0.7560.93
55_S109_M0.7550.93
103_T137_W0.7550.93
155_Q168_P0.7530.93
151_E216_Y0.7510.93
102_E138_R0.7500.93
21_A51_Y0.7470.92
151_E169_T0.7430.92
180_R212_F0.7420.92
23_Q45_Q0.7340.92
78_L82_A0.7320.92
5_K8_P0.7320.92
105_F137_W0.7300.92
144_K150_V0.7290.92
174_T191_T0.7280.92
61_K64_K0.7270.91
75_I83_T0.7220.91
51_Y110_R0.7210.91
57_I112_I0.7200.91
141_A144_K0.7170.91
179_G184_G0.7170.91
30_V138_R0.7150.91
88_V107_Y0.7100.90
100_D103_T0.7080.90
145_K150_V0.7040.90
28_R139_P0.6960.90
99_G141_A0.6910.89
21_A45_Q0.6890.89
50_P114_P0.6870.89
60_E106_F0.6860.89
101_R139_P0.6850.89
92_A96_Q0.6850.89
118_K122_H0.6840.89
108_N134_K0.6840.89
53_A78_L0.6810.89
78_L84_S0.6800.89
7_L10_M0.6790.88
9_L16_L0.6780.88
179_G182_E0.6780.88
191_T202_T0.6690.88
156_V163_L0.6670.88
134_K174_T0.6660.87
45_Q114_P0.6650.87
23_Q131_S0.6590.87
32_N136_F0.6550.87
158_Q208_S0.6540.87
163_L212_F0.6540.87
14_I157_S0.6530.86
97_L103_T0.6520.86
178_L202_T0.6510.86
145_K153_Q0.6500.86
111_E128_A0.6470.86
74_P112_I0.6460.86
51_Y55_S0.6410.85
134_K138_R0.6390.85
59_N67_A0.6390.85
175_I214_L0.6370.85
106_F134_K0.6330.85
22_V51_Y0.6310.85
14_I18_C0.6220.84
181_N211_Q0.6210.84
97_L100_D0.6200.83
151_E154_L0.6190.83
27_T138_R0.6190.83
59_N66_D0.6170.83
138_R196_P0.6150.83
24_P45_Q0.6140.83
9_L14_I0.6120.83
69_L103_T0.6110.83
162_Q204_T0.6060.82
15_S18_C0.6040.82
19_N163_L0.6020.82
55_S84_S0.5990.81
154_L216_Y0.5990.81
52_L110_R0.5980.81
146_A150_V0.5970.81
42_I114_P0.5960.81
60_E132_R0.5940.81
200_V203_N0.5940.81
217_M224_R0.5910.80
113_P128_A0.5910.80
16_L225_M0.5890.80
16_L19_N0.5890.80
24_P52_L0.5880.80
24_P131_S0.5860.80
125_L132_R0.5860.80
55_S76_Q0.5850.80
60_E104_L0.5820.79
52_L171_Y0.5810.79
87_R113_P0.5770.79
46_S110_R0.5740.79
11_L15_S0.5720.78
69_L137_W0.5700.78
111_E214_L0.5690.78
106_F174_T0.5690.78
31_F35_D0.5670.78
65_S115_A0.5620.77
129_I191_T0.5610.77
28_R219_D0.5610.77
56_W131_S0.5600.77
31_F36_K0.5570.76
96_Q99_G0.5550.76
39_S127_V0.5550.76
70_V89_V0.5540.76
51_Y78_L0.5520.76
177_Y181_N0.5510.76
103_T142_L0.5510.76
144_K153_Q0.5500.76
40_L88_V0.5490.75
156_V212_F0.5480.75
8_P17_G0.5470.75
111_E130_Q0.5470.75
6_G10_M0.5440.75
41_R110_R0.5430.75
172_Y198_S0.5410.74
194_V198_S0.5380.74
106_F109_M0.5370.74
39_S50_P0.5350.74
81_K157_S0.5350.74
28_R100_D0.5340.73
165_L175_I0.5320.73
198_S207_Y0.5320.73
57_I105_F0.5310.73
22_V42_I0.5310.73
178_L204_T0.5290.73
139_P196_P0.5290.73
54_Y87_R0.5280.73
58_E130_Q0.5270.72
46_S106_F0.5270.72
68_L105_F0.5250.72
75_I181_N0.5250.72
58_E127_V0.5240.72
5_K17_G0.5240.72
138_R171_Y0.5230.72
163_L201_N0.5220.72
138_R142_L0.5210.72
111_E174_T0.5180.71
123_A126_Q0.5170.71
46_S84_S0.5160.71
26_R84_S0.5160.71
42_I109_M0.5160.71
55_S88_V0.5140.71
35_D95_T0.5130.70
192_V202_T0.5120.70
30_V134_K0.5100.70
151_E168_P0.5100.70
16_L157_S0.5100.70
72_L87_R0.5080.70
183_K186_L0.5080.70
189_F194_V0.5060.69
106_F130_Q0.5060.69
56_W106_F0.5040.69
7_L12_L0.5040.69
142_L170_A0.5040.69
181_N213_Y0.5030.69
37_A68_L0.5020.69
181_N210_S0.5020.69
180_R204_T0.5020.69
112_I129_I0.5010.69
7_L211_Q0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xg5A 1 0.8802 100 0.149 Contact Map
2co7B 1 0.8099 100 0.161 Contact Map
3gfuC 1 0.8512 100 0.164 Contact Map
1klfA 1 0.8347 100 0.167 Contact Map
1l4iA 2 0.781 100 0.172 Contact Map
3q48A 1 0.781 100 0.176 Contact Map
4djmA 1 0.8223 100 0.208 Contact Map
4ay0A 2 0.781 100 0.211 Contact Map
4ncdA 2 0.8017 100 0.26 Contact Map
1mspA 3 0.4669 91.1 0.918 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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