GREMLIN Database
YBGO - Uncharacterized protein YbgO
UniProt: P75748 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13311
Length: 353 (312)
Sequences: 205 (152)
Seq/√Len: 8.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
184_I204_K3.2430.93
250_F327_A3.2280.93
189_D193_S3.1560.92
187_Q193_S3.0600.90
56_I209_G3.0100.90
99_G187_Q2.8790.87
82_Y189_D2.5350.79
190_G202_N2.4900.78
166_V306_N2.4540.77
183_Y311_Y2.3870.75
45_A214_R2.3690.74
79_E187_Q2.3640.74
82_Y192_G2.2960.72
192_G348_F2.2920.72
189_D202_N2.2600.71
195_N202_N2.2490.70
157_T202_N2.2270.69
189_D195_N2.2200.69
233_F329_L2.1770.68
16_L32_G2.1560.67
214_R270_S2.0950.64
329_L342_F2.0870.64
51_K352_Y2.0840.64
218_C262_C2.0760.64
193_S202_N2.0660.63
187_Q195_N2.0370.62
24_L81_V2.0010.61
81_V191_A1.9990.61
331_S336_P1.9870.60
79_E99_G1.9730.60
190_G218_C1.9640.59
84_W187_Q1.9330.58
78_S213_I1.9290.58
269_S310_E1.8640.55
84_W189_D1.8560.55
321_Y324_T1.8300.54
84_W194_V1.8190.53
41_I207_I1.8060.53
95_Y352_Y1.7960.52
218_C233_F1.7850.52
26_C186_V1.7560.50
99_G189_D1.7560.50
47_P188_F1.7520.50
63_K159_L1.7380.50
247_S328_E1.7230.49
49_N305_F1.6940.48
57_W99_G1.6770.47
189_D194_V1.6720.47
46_V293_L1.6680.47
57_W190_G1.6680.47
57_W187_Q1.6550.46
286_L331_S1.6530.46
106_D218_C1.6480.46
205_Y226_P1.6420.46
218_C329_L1.6230.45
212_N285_L1.6160.45
23_A26_C1.6140.44
226_P256_K1.6090.44
234_G295_L1.5980.44
14_L102_Y1.5740.43
233_F274_T1.5630.42
87_P187_Q1.5620.42
327_A340_G1.5570.42
272_F342_F1.5530.42
79_E190_G1.5350.41
103_N253_K1.5250.41
89_P272_F1.5220.41
284_A292_K1.5090.40
312_A350_I1.5080.40
187_Q190_G1.5010.40
24_L187_Q1.4810.39
57_W84_W1.4720.39
276_E345_V1.4530.38
22_M232_D1.4520.38
233_F262_C1.4290.37
59_S218_C1.4180.36
54_D107_Y1.4160.36
21_A326_T1.4080.36
15_F103_N1.4060.36
162_M203_L1.3900.35
284_A293_L1.3830.35
293_L346_V1.3770.35
52_P95_Y1.3740.35
233_F256_K1.3730.35
189_D192_G1.3710.35
88_Y204_K1.3690.35
284_A344_T1.3650.34
58_E268_V1.3610.34
226_P233_F1.3590.34
180_L207_I1.3280.33
290_G293_L1.3240.33
190_G195_N1.3230.33
70_N220_V1.3170.33
47_P220_V1.3160.33
21_A334_G1.3080.32
49_N110_S1.3030.32
327_A342_F1.3000.32
57_W209_G1.2980.32
99_G202_N1.2960.32
80_H117_D1.2900.32
252_I341_P1.2860.31
26_C218_C1.2840.31
267_K314_F1.2810.31
210_L233_F1.2700.31
56_I86_N1.2650.31
242_R295_L1.2630.31
46_V266_F1.2620.31
163_R298_E1.2540.30
147_G209_G1.2510.30
218_C342_F1.2490.30
81_V352_Y1.2380.30
158_F208_T1.2330.29
167_K274_T1.2130.29
33_G217_D1.2100.29
99_G165_Y1.2070.29
106_D187_Q1.2030.28
233_F342_F1.1950.28
68_C340_G1.1750.27
56_I267_K1.1690.27
294_R328_E1.1680.27
220_V295_L1.1650.27
20_S49_N1.1620.27
286_L289_N1.1610.27
99_G262_C1.1580.27
159_L236_F1.1560.27
13_L192_G1.1560.27
66_V158_F1.1550.27
84_W99_G1.1540.27
46_V202_N1.1530.27
94_R306_N1.1460.27
79_E84_W1.1400.26
49_N117_D1.1390.26
340_G352_Y1.1380.26
90_G156_R1.1350.26
220_V244_H1.1350.26
84_W193_S1.1330.26
44_F95_Y1.1320.26
256_K352_Y1.1270.26
220_V233_F1.1250.26
59_S165_Y1.1150.25
26_C59_S1.1070.25
84_W195_N1.1040.25
161_R291_L1.1000.25
83_A107_Y1.0920.25
63_K161_R1.0910.25
67_Y96_Y1.0780.24
107_Y166_V1.0740.24
64_I203_L1.0720.24
108_D213_I1.0710.24
154_M251_S1.0700.24
238_L257_S1.0670.24
87_P194_V1.0660.24
79_E189_D1.0650.24
11_I30_T1.0550.24
115_R159_L1.0530.24
47_P226_P1.0510.23
187_Q202_N1.0490.23
284_A309_A1.0470.23
47_P256_K1.0470.23
42_Q84_W1.0450.23
91_V231_I1.0440.23
311_Y325_Y1.0430.23
65_P157_T1.0400.23
168_I352_Y1.0320.23
44_F58_E1.0250.23
294_R302_P1.0210.23
160_A222_F1.0180.22
224_I262_C1.0180.22
232_D295_L1.0140.22
57_W87_P1.0130.22
79_E195_N1.0100.22
49_N147_G1.0090.22
125_K213_I1.0000.22
11_I19_K0.9860.22
224_I277_T0.9850.22
99_G190_G0.9820.21
347_L352_Y0.9780.21
265_G313_D0.9750.21
148_D295_L0.9730.21
124_S249_T0.9720.21
202_N213_I0.9690.21
26_C190_G0.9640.21
26_C57_W0.9590.21
226_P305_F0.9580.21
273_Y285_L0.9510.21
248_K305_F0.9480.20
287_I311_Y0.9460.20
59_S190_G0.9350.20
99_G106_D0.9320.20
220_V352_Y0.9300.20
51_K300_A0.9280.20
214_R343_D0.9280.20
164_L322_E0.9250.20
167_K347_L0.9220.20
325_Y331_S0.9200.20
99_G218_C0.9190.20
95_Y170_E0.9180.20
282_D285_L0.9160.20
256_K262_C0.9150.20
47_P352_Y0.9150.20
46_V220_V0.9140.20
50_A56_I0.9100.19
328_E352_Y0.9040.19
105_V147_G0.9030.19
238_L261_Q0.9030.19
185_V202_N0.9000.19
235_K322_E0.8970.19
174_H304_T0.8940.19
100_V290_G0.8920.19
285_L289_N0.8910.19
183_Y293_L0.8910.19
64_I162_M0.8850.19
187_Q218_C0.8840.19
306_N316_S0.8840.19
57_W202_N0.8790.19
190_G193_S0.8760.19
96_Y184_I0.8750.19
223_S227_E0.8740.19
166_V342_F0.8690.18
63_K304_T0.8680.18
100_V122_I0.8670.18
56_I81_V0.8630.18
82_Y245_T0.8610.18
57_W189_D0.8610.18
103_N338_E0.8580.18
107_Y163_R0.8490.18
31_S214_R0.8460.18
40_A170_E0.8440.18
262_C342_F0.8440.18
10_V239_L0.8400.18
166_V180_L0.8400.18
303_Y310_E0.8390.18
57_W79_E0.8240.17
233_F325_Y0.8230.17
47_P227_E0.8190.17
106_D233_F0.8190.17
160_A285_L0.8180.17
175_D344_T0.8180.17
170_E244_H0.8170.17
282_D324_T0.8160.17
25_N201_Q0.8140.17
219_S263_T0.8140.17
166_V291_L0.8140.17
266_F290_G0.8130.17
220_V256_K0.8090.17
166_V270_S0.8050.17
242_R298_E0.8030.17
51_K168_I0.7990.17
311_Y349_K0.7980.17
97_Q203_L0.7970.17
49_N248_K0.7970.17
28_F295_L0.7920.16
66_V351_N0.7900.16
26_C187_Q0.7880.16
274_T289_N0.7880.16
58_E349_K0.7850.16
46_V195_N0.7850.16
238_L304_T0.7820.16
10_V24_L0.7790.16
231_I346_V0.7750.16
275_E345_V0.7750.16
242_R334_G0.7740.16
48_G198_P0.7720.16
106_D190_G0.7720.16
106_D329_L0.7700.16
292_K344_T0.7670.16
251_S257_S0.7660.16
79_E193_S0.7640.16
48_G244_H0.7630.16
83_A101_T0.7620.16
107_Y207_I0.7610.16
286_L349_K0.7560.16
217_D275_E0.7550.16
97_Q346_V0.7530.16
288_G292_K0.7510.16
115_R295_L0.7490.16
118_T271_S0.7490.16
98_L348_F0.7480.15
58_E308_Y0.7380.15
118_T231_I0.7380.15
219_S268_V0.7370.15
96_Y346_V0.7350.15
44_F83_A0.7320.15
344_T349_K0.7300.15
270_S342_F0.7270.15
64_I352_Y0.7270.15
324_T348_F0.7270.15
84_W202_N0.7260.15
110_S114_S0.7260.15
179_T243_R0.7260.15
261_Q350_I0.7240.15
226_P284_A0.7240.15
256_K274_T0.7230.15
19_K303_Y0.7220.15
168_I312_A0.7220.15
18_L286_L0.7210.15
98_L292_K0.7140.15
218_C226_P0.7130.15
87_P331_S0.7110.15
47_P232_D0.7110.15
82_Y236_F0.7100.15
116_I147_G0.7100.15
38_S166_V0.7070.15
24_L343_D0.7030.15
86_N262_C0.7020.14
67_Y221_N0.7020.14
227_E247_S0.7010.14
214_R222_F0.7010.14
251_S341_P0.7000.14
117_D248_K0.6960.14
210_L262_C0.6920.14
43_P146_S0.6860.14
47_P264_D0.6860.14
271_S349_K0.6850.14
13_L279_V0.6830.14
162_M189_D0.6830.14
81_V188_F0.6800.14
210_L250_F0.6790.14
226_P274_T0.6780.14
66_V352_Y0.6770.14
222_F290_G0.6750.14
273_Y349_K0.6710.14
165_Y311_Y0.6700.14
310_E323_K0.6690.14
24_L189_D0.6680.14
23_A68_C0.6650.14
106_D165_Y0.6630.14
264_D352_Y0.6620.14
99_G342_F0.6620.14
284_A291_L0.6600.14
46_V289_N0.6600.14
245_T303_Y0.6590.14
22_M73_N0.6570.14
308_Y349_K0.6560.14
168_I205_Y0.6560.14
35_V276_E0.6560.14
224_I329_L0.6550.14
102_Y308_Y0.6540.14
99_G233_F0.6480.13
33_G213_I0.6480.13
59_S87_P0.6470.13
93_D214_R0.6460.13
264_D346_V0.6460.13
86_N118_T0.6450.13
26_C53_G0.6440.13
233_F306_N0.6420.13
62_I205_Y0.6420.13
50_A145_C0.6350.13
57_W106_D0.6350.13
11_I242_R0.6340.13
79_E106_D0.6310.13
101_T285_L0.6310.13
164_L170_E0.6290.13
326_T343_D0.6270.13
114_S198_P0.6270.13
57_W165_Y0.6260.13
84_W218_C0.6210.13
95_Y205_Y0.6200.13
164_L194_V0.6200.13
108_D165_Y0.6190.13
331_S349_K0.6180.13
276_E325_Y0.6180.13
291_L329_L0.6170.13
325_Y346_V0.6170.13
50_A268_V0.6150.13
54_D219_S0.6150.13
304_T325_Y0.6140.13
171_M272_F0.6120.13
55_K166_V0.6100.13
165_Y216_L0.6100.13
233_F250_F0.6040.13
26_C262_C0.6020.13
59_S272_F0.6010.12
158_F328_E0.6010.12
55_K163_R0.6000.12
12_C318_M0.6000.12
46_V104_G0.6000.12
270_S331_S0.5990.12
77_E251_S0.5980.12
79_E82_Y0.5980.12
38_S100_V0.5970.12
55_K58_E0.5960.12
27_Y33_G0.5960.12
225_S253_K0.5950.12
175_D222_F0.5950.12
16_L120_Q0.5930.12
47_P233_F0.5910.12
231_I333_P0.5900.12
250_F340_G0.5900.12
266_F293_L0.5900.12
160_A191_A0.5890.12
19_K191_A0.5890.12
80_H100_V0.5880.12
11_I98_L0.5880.12
29_G155_S0.5870.12
159_L321_Y0.5870.12
271_S351_N0.5860.12
24_L252_I0.5860.12
165_Y202_N0.5860.12
213_I264_D0.5830.12
56_I216_L0.5820.12
211_E224_I0.5790.12
81_V86_N0.5790.12
160_A194_V0.5760.12
83_A256_K0.5760.12
188_F273_Y0.5750.12
233_F289_N0.5740.12
262_C329_L0.5730.12
200_A274_T0.5710.12
282_D332_I0.5710.12
100_V264_D0.5700.12
83_A102_Y0.5700.12
27_Y236_F0.5700.12
313_D352_Y0.5700.12
49_N125_K0.5680.12
175_D218_C0.5660.12
186_V214_R0.5660.12
55_K349_K0.5610.12
92_Q96_Y0.5610.12
231_I240_D0.5560.12
168_I241_I0.5540.12
61_D163_R0.5530.12
230_V239_L0.5520.12
157_T236_F0.5520.12
47_P289_N0.5490.12
329_L332_I0.5490.12
103_N207_I0.5490.12
106_D262_C0.5460.12
79_E158_F0.5440.11
220_V268_V0.5430.11
311_Y351_N0.5410.11
195_N251_S0.5410.11
279_V346_V0.5370.11
64_I166_V0.5360.11
49_N219_S0.5330.11
222_F275_E0.5320.11
295_L303_Y0.5310.11
55_K62_I0.5300.11
124_S240_D0.5290.11
304_T307_K0.5260.11
165_Y266_F0.5260.11
31_S73_N0.5260.11
329_L341_P0.5240.11
46_V222_F0.5240.11
48_G185_V0.5230.11
66_V203_L0.5210.11
289_N326_T0.5200.11
318_M331_S0.5190.11
13_L197_D0.5180.11
88_Y176_Y0.5160.11
305_F330_S0.5150.11
102_Y216_L0.5140.11
175_D220_V0.5130.11
99_G193_S0.5120.11
224_I227_E0.5110.11
286_L293_L0.5100.11
36_E231_I0.5100.11
93_D243_R0.5090.11
248_K268_V0.5070.11
84_W184_I0.5060.11
25_N70_N0.5050.11
342_F348_F0.5050.11
20_S251_S0.5040.11
344_T348_F0.5040.11
48_G215_V0.5040.11
115_R122_I0.5030.11
177_Q183_Y0.5000.11
282_D301_S0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3jwnH 1 0.7507 99.8 0.803 Contact Map
5afoA 1 0.8272 99.8 0.81 Contact Map
2jmrA 1 0.4023 99.6 0.838 Contact Map
2w07B 1 0.3314 99.6 0.839 Contact Map
3bwuF 1 0.3258 99.6 0.839 Contact Map
2xg5B 1 0.3768 99.6 0.841 Contact Map
2uy6B 2 0.3938 99.6 0.842 Contact Map
2jtyA 1 0.4164 99.5 0.843 Contact Map
1pdkB 1 0.3711 99.5 0.846 Contact Map
4dwhB 1 0.3598 99.5 0.846 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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