GREMLIN Database
YBGL - UPF0271 protein YbgL
UniProt: P75746 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13308
Length: 244 (240)
Sequences: 2298 (1594)
Seq/√Len: 102.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
48_I98_G3.3481.00
38_Q80_A3.0701.00
21_T50_N3.0571.00
167_A204_T2.9001.00
90_A94_R2.7761.00
167_A206_E2.7661.00
24_S242_V2.5731.00
60_F112_Q2.4761.00
193_E207_W2.4201.00
167_A202_S2.3991.00
199_R207_W2.2951.00
87_G91_T2.2861.00
202_S206_E2.2851.00
137_V214_T2.2561.00
70_A112_Q2.2541.00
40_M89_L2.1991.00
193_E197_H2.1351.00
83_L130_C2.0991.00
90_A130_C2.0891.00
164_G172_V2.0711.00
143_E146_R2.0621.00
135_I156_R2.0561.00
41_Q96_Q2.0521.00
117_A143_E2.0361.00
45_R96_Q2.0221.00
191_T215_V1.9931.00
159_V212_A1.9911.00
61_P71_M1.9601.00
65_N69_S1.9601.00
79_Y129_A1.9361.00
79_Y125_R1.9281.00
166_Q173_P1.8871.00
44_V92_I1.8581.00
164_G178_G1.8391.00
41_Q80_A1.7911.00
15_S18_E1.7631.00
121_D150_Q1.7371.00
4_D25_S1.7101.00
23_V26_A1.7051.00
32_F84_Y1.7041.00
201_K207_W1.7021.00
12_G39_I1.6961.00
166_Q176_Q1.6481.00
124_A147_A1.6361.00
164_G180_L1.6301.00
54_I98_G1.6241.00
193_E199_R1.6201.00
20_L23_V1.6091.00
232_R236_A1.6011.00
166_Q170_S1.5861.00
113_A123_I1.5821.00
184_E188_L1.5771.00
217_L228_A1.5751.00
166_Q172_V1.5631.00
44_V93_A1.5581.00
93_A98_G1.5431.00
138_G155_T1.5091.00
187_A227_F1.5021.00
115_K170_S1.4951.00
61_P81_Q1.4851.00
78_V119_L1.4791.00
73_L78_V1.4751.00
41_Q45_R1.4261.00
164_G190_Q1.4201.00
156_R213_Q1.4181.00
138_G145_I1.4051.00
173_P176_Q1.3981.00
188_L234_A1.3821.00
164_G203_I1.3811.00
145_I157_E1.3801.00
192_L234_A1.3741.00
193_E201_K1.3721.00
199_R209_T1.3610.99
70_A116_E1.3600.99
4_D24_S1.3550.99
125_R129_A1.3540.99
145_I155_T1.3000.99
185_E230_R1.2920.99
17_A46_E1.2880.99
70_A115_K1.2860.99
64_E81_Q1.2830.99
181_I187_A1.2750.99
197_H207_W1.2700.99
86_I130_C1.2630.99
221_G227_F1.2560.99
112_Q119_L1.2550.99
104_K216_C1.2540.99
121_D151_Y1.2510.99
20_L50_N1.2460.99
121_D147_A1.2430.99
196_Q238_K1.2420.99
113_A144_L1.2340.99
161_A215_V1.2290.99
226_A229_R1.2240.99
234_A238_K1.2200.99
184_E230_R1.2180.99
84_Y88_A1.1980.99
143_E147_A1.1920.99
44_V54_I1.1910.99
103_V127_V1.1690.98
200_V208_A1.1640.98
112_Q116_E1.1500.98
53_A101_R1.1410.98
121_D125_R1.1360.98
38_Q77_T1.1210.98
73_L81_Q1.1200.98
46_E49_K1.1150.98
93_A100_M1.1030.98
46_E50_N1.0940.98
44_V89_L1.0920.98
183_N186_Q1.0710.97
236_A242_V1.0680.97
125_R151_Y1.0680.97
157_E213_Q1.0650.97
147_A150_Q1.0650.97
202_S208_A1.0610.97
42_A46_E1.0600.97
3_I195_V1.0590.97
158_E216_C1.0550.97
124_A153_L1.0520.97
145_I149_K1.0470.97
102_H137_V1.0460.97
148_G155_T1.0400.97
104_K158_E1.0300.96
124_A148_G1.0290.96
76_E80_A1.0290.96
74_P77_T1.0280.96
128_Y151_Y1.0200.96
84_Y87_G1.0180.96
124_A151_Y1.0170.96
172_V203_I1.0150.96
233_S237_E1.0130.96
191_T195_V1.0050.96
32_F81_Q1.0020.96
180_L221_G0.9980.96
83_L95_A0.9930.96
138_G144_L0.9920.96
117_A147_A0.9840.95
131_D134_L0.9740.95
233_S236_A0.9740.95
122_A126_A0.9610.95
159_V194_M0.9500.94
48_I54_I0.9440.94
36_D65_N0.9420.94
86_I103_V0.9340.94
185_E189_A0.9330.94
28_I43_C0.9300.94
154_T213_Q0.9280.94
45_R49_K0.9210.93
17_A42_A0.9090.93
26_A52_V0.9060.93
156_R214_T0.9030.93
161_A191_T0.8950.92
12_G43_C0.8940.92
192_L196_Q0.8920.92
18_E21_T0.8770.92
137_V156_R0.8720.91
194_M212_A0.8720.91
99_V131_D0.8590.91
59_S71_M0.8580.91
127_V153_L0.8540.91
114_A170_S0.8510.90
149_K211_A0.8500.90
101_R137_V0.8480.90
131_D154_T0.8480.90
163_R174_R0.8470.90
10_G43_C0.8410.90
37_A84_Y0.8400.90
22_L228_A0.8320.89
20_L47_A0.8300.89
186_Q189_A0.8300.89
53_A102_H0.8280.89
92_I96_Q0.8260.89
186_Q190_Q0.8250.89
133_A154_T0.8240.89
28_I54_I0.8230.89
117_A146_R0.8200.89
111_N174_R0.8180.89
117_A121_D0.8040.88
9_L20_L0.8010.88
42_A45_R0.7970.87
12_G19_L0.7830.86
166_Q203_I0.7820.86
235_F240_I0.7790.86
13_C57_H0.7790.86
79_Y83_L0.7790.86
229_R233_S0.7740.86
60_F78_V0.7720.86
113_A119_L0.7670.85
7_A19_L0.7640.85
194_M200_V0.7630.85
135_I154_T0.7610.85
124_A128_Y0.7610.85
104_K110_Y0.7530.84
159_V215_V0.7480.84
30_C56_A0.7440.83
61_P64_E0.7420.83
190_Q194_M0.7420.83
196_Q240_I0.7410.83
192_L238_K0.7410.83
48_I93_A0.7410.83
22_L225_L0.7380.83
189_A234_A0.7370.83
120_A147_A0.7360.83
200_V210_V0.7340.83
64_E73_L0.7340.83
157_E211_A0.7300.82
149_K157_E0.7280.82
187_A190_Q0.7230.82
105_P123_I0.7230.82
110_Y160_F0.7230.82
102_H135_I0.7190.81
22_L232_R0.7180.81
40_M57_H0.7180.81
47_A54_I0.7100.81
75_P122_A0.7070.80
78_V81_Q0.7040.80
182_E223_H0.7040.80
105_P110_Y0.7000.80
142_S145_I0.6980.79
136_L144_L0.6970.79
140_A157_E0.6970.79
110_Y158_E0.6950.79
185_E234_A0.6860.78
21_T229_R0.6850.78
111_N163_R0.6830.78
54_I93_A0.6810.78
115_K168_D0.6770.77
83_L129_A0.6770.77
171_L174_R0.6660.76
161_A231_L0.6660.76
111_N173_P0.6650.76
128_Y132_P0.6650.76
20_L26_A0.6640.76
77_T175_S0.6580.75
184_E223_H0.6550.75
111_N171_L0.6530.75
111_N114_A0.6520.75
188_L230_R0.6460.74
139_L160_F0.6440.74
114_A142_S0.6420.74
22_L229_R0.6410.73
195_V240_I0.6400.73
176_Q203_I0.6400.73
174_R179_A0.6390.73
147_A151_Y0.6390.73
14_A65_N0.6380.73
9_L26_A0.6380.73
110_Y138_G0.6380.73
183_N190_Q0.6340.73
88_A91_T0.6320.72
84_Y91_T0.6320.72
14_A69_S0.6280.72
90_A131_D0.6280.72
104_K160_F0.6270.72
7_A217_L0.6260.72
44_V98_G0.6190.71
171_L179_A0.6170.71
41_Q92_I0.6170.71
69_S77_T0.6130.70
78_V82_T0.6120.70
7_A23_V0.6110.70
16_D43_C0.6100.70
12_G63_R0.6090.70
136_L148_G0.6090.70
37_A88_A0.6080.69
94_R99_V0.6080.69
83_L126_A0.6080.69
139_L142_S0.6070.69
41_Q95_A0.6060.69
163_R173_P0.6040.69
61_P73_L0.6040.69
160_F216_C0.6040.69
44_V96_Q0.6020.69
110_Y139_L0.6000.68
29_A36_D0.5970.68
94_R130_C0.5940.68
59_S63_R0.5920.67
87_G92_I0.5910.67
164_G181_I0.5900.67
75_P118_Q0.5900.67
32_F37_A0.5870.67
188_L227_F0.5850.67
4_D53_A0.5850.67
120_A144_L0.5850.67
36_D39_I0.5840.66
19_L228_A0.5830.66
195_V235_F0.5800.66
6_N104_K0.5790.66
110_Y216_C0.5780.66
19_L22_L0.5780.66
73_L77_T0.5770.65
3_I215_V0.5740.65
13_C219_G0.5730.65
164_G179_A0.5720.65
186_Q201_K0.5710.65
78_V122_A0.5700.65
91_T130_C0.5700.65
46_E52_V0.5690.64
82_T122_A0.5690.64
58_P82_T0.5690.64
192_L235_F0.5680.64
136_L153_L0.5680.64
6_N216_C0.5670.64
221_G224_A0.5670.64
172_V176_Q0.5660.64
197_H200_V0.5660.64
232_R242_V0.5650.64
189_A193_E0.5640.64
39_I64_E0.5630.64
230_R234_A0.5630.64
236_A241_V0.5610.63
7_A219_G0.5600.63
54_I100_M0.5590.63
60_F73_L0.5580.63
144_L148_G0.5570.63
87_G95_A0.5500.62
128_Y133_A0.5500.62
44_V57_H0.5480.61
75_P125_R0.5480.61
174_R178_G0.5480.61
119_L214_T0.5430.61
74_P78_V0.5430.61
37_A87_G0.5350.60
98_G101_R0.5340.60
60_F70_A0.5330.59
48_I97_G0.5320.59
83_L90_A0.5320.59
222_E226_A0.5310.59
36_D69_S0.5300.59
225_L228_A0.5290.59
146_R150_Q0.5290.59
86_I90_A0.5270.59
146_R149_K0.5270.59
234_A237_E0.5270.59
191_T194_M0.5260.58
84_Y92_I0.5230.58
39_I92_I0.5230.58
26_A47_A0.5210.58
172_V190_Q0.5180.57
105_P144_L0.5170.57
164_G175_S0.5160.57
63_R69_S0.5160.57
43_C191_T0.5150.57
10_G29_A0.5150.57
32_F39_I0.5140.57
127_V131_D0.5140.57
76_E79_Y0.5130.57
5_L217_L0.5110.56
118_Q121_D0.5110.56
126_A130_C0.5080.56
226_A233_S0.5050.55
42_A76_E0.5040.55
14_A84_Y0.5040.55
174_R177_S0.5030.55
105_P113_A0.5020.55
79_Y126_A0.5020.55
28_I98_G0.5020.55
82_T126_A0.5000.55
65_N91_T0.5000.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1xw8A 2 0.9303 100 0.006 Contact Map
1v6tA 4 0.9795 100 0.011 Contact Map
2dfaA 4 0.9877 100 0.012 Contact Map
2xu2A 4 0.9549 100 0.036 Contact Map
2i5iA 4 0.8811 96.6 0.93 Contact Map
4m1bA 1 0.7008 88.6 0.95 Contact Map
2vyoA 1 0.7336 84.1 0.953 Contact Map
1ny1A 1 0.7131 73.7 0.957 Contact Map
2qv5A 1 0.8156 66 0.96 Contact Map
2e67A 2 0.8197 64.5 0.96 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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