GREMLIN Database
YBGK - Uncharacterized protein YbgK
UniProt: P75745 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13307
Length: 310 (285)
Sequences: 3124 (2188)
Seq/√Len: 129.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
37_L52_A5.0701.00
82_D98_Q5.0311.00
40_A114_A4.1761.00
175_R265_D3.7551.00
72_L79_A3.3121.00
70_F94_M3.2181.00
51_P128_C3.2161.00
11_T53_L3.1481.00
3_K65_E3.0851.00
3_K63_E3.0161.00
95_K98_Q2.9641.00
67_D95_K2.7141.00
13_V119_I2.6011.00
55_I113_L2.5041.00
80_R101_T2.3781.00
70_F92_L2.3511.00
36_A168_L2.2841.00
63_E99_R2.2801.00
4_I62_V2.2321.00
64_F94_M2.1561.00
64_F68_G2.1251.00
123_P128_C2.0991.00
38_R48_A2.0901.00
5_I63_E2.0821.00
273_P276_Q2.0451.00
194_W282_Q2.0151.00
284_S287_E2.0021.00
185_F236_V1.9751.00
173_R281_V1.9591.00
176_A234_V1.9591.00
61_T101_T1.9511.00
32_L246_M1.9221.00
3_K149_R1.9061.00
175_R262_I1.9041.00
67_D96_A1.8981.00
81_L94_M1.8871.00
61_T99_R1.8791.00
66_T96_A1.8781.00
197_P279_H1.8741.00
31_A37_L1.8721.00
197_P277_P1.8571.00
115_V119_I1.8521.00
181_E257_R1.8311.00
262_I283_C1.8301.00
176_A259_A1.8121.00
7_A146_D1.8071.00
199_Q277_P1.8031.00
81_L86_V1.7291.00
77_C102_L1.6971.00
16_G38_R1.6971.00
262_I265_D1.6921.00
244_V269_L1.6511.00
77_C111_S1.6491.00
56_T110_R1.6361.00
86_V92_L1.6141.00
78_E103_K1.5991.00
87_W92_L1.5921.00
27_S131_D1.5781.00
261_I265_D1.5681.00
64_F100_L1.5531.00
172_N272_I1.5461.00
76_G106_Q1.5321.00
55_I111_S1.5271.00
178_P282_Q1.5061.00
201_S212_Q1.4851.00
10_Y132_L1.4671.00
234_V244_V1.4641.00
142_R148_D1.4601.00
40_A44_V1.4591.00
212_Q241_Q1.4521.00
55_I60_L1.4311.00
188_A217_K1.4291.00
40_A73_T1.4261.00
178_P190_Q1.4231.00
34_M267_Y1.4161.00
231_P249_A1.3941.00
31_A52_A1.3881.00
175_R281_V1.3781.00
216_L236_V1.3771.00
176_A194_W1.3731.00
181_E227_H1.3721.00
133_K205_N1.3521.00
2_L62_V1.3461.00
44_V114_A1.3311.00
68_G152_I1.3291.00
62_V100_L1.3181.00
131_D134_V1.3171.00
189_S216_L1.3131.00
174_I269_L1.3011.00
2_L64_F1.2981.00
22_R249_A1.2881.00
186_D217_K1.2851.00
79_A102_L1.2771.00
44_V71_A1.2691.00
199_Q212_Q1.2651.00
62_V113_L1.2621.00
65_E149_R1.2501.00
44_V69_W1.2471.00
174_I261_I1.2451.00
187_R191_D1.2401.00
5_I99_R1.2371.00
72_L113_L1.2271.00
178_P194_W1.2201.00
52_A114_A1.2160.99
176_A193_F1.2160.99
130_T138_G1.2150.99
73_T89_G1.2130.99
207_M250_Q1.1790.99
171_G277_P1.1770.99
218_R223_E1.1730.99
209_Y246_M1.1720.99
171_G197_P1.1440.99
55_I77_C1.1290.99
145_K148_D1.1270.99
261_I269_L1.1210.99
77_C105_P1.1150.99
53_L144_L1.1070.99
6_R61_T1.0950.99
191_D195_R1.0930.99
246_M270_A1.0860.99
272_I276_Q1.0850.99
193_F280_F1.0770.99
79_A88_T1.0720.99
196_S214_Q1.0600.99
231_P266_M1.0560.99
272_I278_I1.0550.99
70_F100_L1.0510.99
35_P267_Y1.0460.98
5_I61_T1.0420.98
227_H257_R1.0220.98
68_G94_M1.0200.98
198_W243_I1.0080.98
115_V152_I1.0070.98
11_T60_L1.0040.98
121_V128_C1.0030.98
235_Q255_Y1.0010.98
185_F258_I0.9980.98
39_I89_G0.9980.98
32_L209_Y0.9880.98
13_V51_P0.9840.98
50_A128_C0.9820.98
102_L111_S0.9810.98
181_E233_V0.9800.98
26_I136_I0.9790.98
237_P243_I0.9770.98
47_D50_A0.9700.98
230_L260_C0.9670.97
138_G142_R0.9640.97
26_I125_M0.9590.97
69_W93_P0.9530.97
120_D151_P0.9460.97
79_A100_L0.9440.97
43_L71_A0.9390.97
218_R222_R0.9370.97
40_A52_A0.9300.97
7_A11_T0.9260.97
182_Y190_Q0.9240.97
119_I128_C0.9240.97
81_L98_Q0.9230.97
69_W91_R0.9220.97
175_R283_C0.9210.97
67_D93_P0.9150.96
16_G31_A0.9130.96
161_E164_G0.9060.96
198_W241_Q0.9010.96
16_G37_L0.8850.96
228_G233_V0.8850.96
42_L48_A0.8780.96
64_F70_F0.8770.95
178_P182_Y0.8750.95
79_A86_V0.8730.95
194_W259_A0.8690.95
200_L272_I0.8660.95
13_V128_C0.8650.95
119_I150_L0.8610.95
192_A196_S0.8610.95
200_L209_Y0.8610.95
234_V259_A0.8600.95
43_L91_R0.8600.95
109_M273_P0.8590.95
175_R264_A0.8580.95
53_L60_L0.8560.95
230_L233_V0.8490.95
78_E106_Q0.8480.95
71_A114_A0.8470.95
12_T143_L0.8460.95
76_G102_L0.8430.94
89_G166_K0.8390.94
81_L100_L0.8380.94
89_G165_V0.8370.94
46_N118_G0.8330.94
233_V257_R0.8330.94
6_R146_D0.8320.94
285_L289_L0.8310.94
29_C131_D0.8260.94
71_A91_R0.8250.94
229_L245_L0.8200.94
189_S192_A0.8180.93
233_V260_C0.8150.93
13_V53_L0.8150.93
232_G237_P0.8120.93
8_G11_T0.8070.93
41_N46_N0.8060.93
70_F81_L0.8050.93
229_L233_V0.8050.93
10_Y143_L0.8010.93
184_E224_L0.7950.93
193_F258_I0.7840.92
188_A191_D0.7820.92
67_D98_Q0.7800.92
80_R103_K0.7790.92
189_S217_K0.7750.92
193_F234_V0.7730.91
261_I266_M0.7710.91
86_V100_L0.7680.91
198_W213_G0.7680.91
193_F236_V0.7680.91
232_G235_Q0.7670.91
173_R268_H0.7640.91
13_V121_V0.7620.91
173_R279_H0.7620.91
10_Y56_T0.7580.91
37_L49_N0.7570.91
50_A153_G0.7570.91
229_L240_G0.7500.90
82_D85_A0.7440.90
64_F81_L0.7400.90
87_W90_W0.7390.90
133_K207_M0.7380.89
44_V91_R0.7330.89
228_G232_G0.7320.89
102_L113_L0.7290.89
7_A144_L0.7260.89
231_P247_N0.7250.89
22_R28_H0.7220.88
16_G49_N0.7200.88
15_D18_R0.7200.88
34_M247_N0.7170.88
6_R101_T0.7120.88
75_A108_G0.7080.87
193_F259_A0.7070.87
76_G88_T0.7060.87
44_V116_A0.7050.87
177_L285_L0.7040.87
120_D123_P0.7030.87
59_Q103_K0.7010.87
281_V287_E0.7000.87
186_D189_S0.7000.87
89_G168_L0.7000.87
27_S134_V0.6980.87
115_V151_P0.6960.87
187_R190_Q0.6960.87
172_N268_H0.6950.86
62_V94_M0.6940.86
83_D101_T0.6930.86
171_G279_H0.6930.86
162_A165_V0.6930.86
69_W116_A0.6920.86
245_L249_A0.6900.86
121_V151_P0.6890.86
204_S274_L0.6890.86
119_I153_G0.6880.86
14_Q129_S0.6880.86
80_R85_A0.6840.86
72_L111_S0.6820.85
128_C151_P0.6820.85
78_E104_R0.6800.85
32_L247_N0.6780.85
55_I102_L0.6740.85
121_V130_T0.6720.85
51_P119_I0.6720.85
211_L278_I0.6690.84
55_I58_G0.6580.83
22_R251_T0.6570.83
227_H233_V0.6560.83
121_V153_G0.6550.83
81_L92_L0.6520.83
174_I278_I0.6510.83
235_Q240_G0.6510.83
65_E96_A0.6500.83
83_D99_R0.6500.83
12_T132_L0.6490.82
134_V252_T0.6480.82
207_M255_Y0.6470.82
244_V261_I0.6470.82
245_L250_Q0.6470.82
184_E222_R0.6440.82
70_F115_V0.6440.82
39_I42_L0.6440.82
120_D128_C0.6430.82
208_G243_I0.6410.82
4_I144_L0.6410.82
204_S209_Y0.6400.82
198_W280_F0.6340.81
34_M263_E0.6320.81
235_Q253_G0.6310.81
110_R270_A0.6310.81
237_P241_Q0.6300.81
41_N114_A0.6300.81
88_T111_S0.6260.80
227_H238_H0.6260.80
2_L115_V0.6250.80
190_Q282_Q0.6250.80
223_E256_P0.6190.79
138_G148_D0.6180.79
130_T142_R0.6180.79
192_A217_K0.6170.79
9_M58_G0.6140.79
238_H256_P0.6120.79
182_Y194_W0.6100.78
76_G107_H0.6100.78
174_I265_D0.6040.78
224_L256_P0.6040.78
22_R231_P0.6040.78
36_A88_T0.6040.78
28_H249_A0.6020.78
4_I60_L0.5990.77
227_H240_G0.5990.77
55_I72_L0.5970.77
2_L152_I0.5970.77
188_A192_A0.5960.77
181_E225_L0.5940.77
172_N276_Q0.5920.76
133_K257_R0.5900.76
116_A251_T0.5890.76
236_V259_A0.5880.76
223_E226_S0.5860.76
105_P111_S0.5840.75
120_D153_G0.5830.75
37_L114_A0.5830.75
247_N267_Y0.5800.75
226_S251_T0.5800.75
226_S235_Q0.5800.75
264_A267_Y0.5790.75
224_L227_H0.5790.75
40_A71_A0.5750.74
229_L238_H0.5740.74
36_A39_I0.5740.74
224_L252_T0.5700.74
121_V142_R0.5700.74
190_Q194_W0.5690.74
283_C287_E0.5690.74
181_E224_L0.5680.73
226_S255_Y0.5650.73
250_Q257_R0.5640.73
222_R256_P0.5630.73
226_S254_G0.5620.73
218_R224_L0.5610.72
229_L250_Q0.5600.72
184_E220_T0.5590.72
215_I241_Q0.5570.72
11_T144_L0.5570.72
204_S210_R0.5570.72
283_C288_A0.5560.72
72_L102_L0.5560.72
70_F86_V0.5550.72
52_A119_I0.5550.72
80_R83_D0.5540.72
222_R225_L0.5530.71
231_P240_G0.5530.71
231_P251_T0.5520.71
128_C153_G0.5510.71
108_G271_Q0.5510.71
168_L172_N0.5480.71
175_R261_I0.5480.71
247_N266_M0.5450.70
262_I288_A0.5450.70
132_L205_N0.5440.70
228_G235_Q0.5440.70
34_M266_M0.5440.70
232_G238_H0.5440.70
184_E218_R0.5390.69
41_N50_A0.5380.69
142_R145_K0.5380.69
63_E97_G0.5370.69
107_H170_W0.5370.69
46_N117_G0.5360.69
6_R9_M0.5360.69
207_M245_L0.5360.69
189_S236_V0.5300.68
94_M100_L0.5300.68
269_L272_I0.5290.68
226_S252_T0.5290.68
228_G237_P0.5270.68
262_I281_V0.5260.68
29_C127_S0.5260.68
236_V242_P0.5260.68
66_T152_I0.5250.67
91_R274_L0.5250.67
60_L103_K0.5250.67
228_G234_V0.5230.67
165_V168_L0.5230.67
6_R281_V0.5230.67
11_T55_I0.5220.67
209_Y272_I0.5210.67
218_R221_D0.5210.67
227_H239_N0.5200.67
210_R243_I0.5200.67
206_R248_D0.5190.67
76_G89_G0.5190.67
16_G19_H0.5190.67
180_P252_T0.5160.66
160_M163_Q0.5160.66
75_A103_K0.5160.66
231_P267_Y0.5150.66
234_V275_G0.5140.66
122_P128_C0.5140.66
73_T88_T0.5130.66
75_A111_S0.5130.66
73_T114_A0.5110.65
181_E229_L0.5110.65
119_I152_I0.5100.65
4_I53_L0.5100.65
129_S151_P0.5090.65
234_V238_H0.5090.65
180_P260_C0.5090.65
9_M57_L0.5090.65
130_T137_G0.5080.65
60_L105_P0.5080.65
229_L235_Q0.5070.65
15_D129_S0.5070.65
121_V124_V0.5060.65
181_E184_E0.5050.65
22_R252_T0.5050.65
134_V243_I0.5040.64
227_H232_G0.5020.64
186_D219_T0.5000.64
27_S133_K0.5000.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3mmlA 2 0.9194 100 0.074 Contact Map
3va7A 1 0.9968 100 0.103 Contact Map
3oepA 1 0.8742 100 0.126 Contact Map
2zp2A 1 0.3452 89.7 0.952 Contact Map
1x7fA 1 0.8419 74.1 0.96 Contact Map
3gmgA 2 0.4258 71.9 0.961 Contact Map
1f0zA 1 0.1839 56.6 0.964 Contact Map
2phcB 1 0.6323 53.8 0.965 Contact Map
1vykA 1 0.1613 50.8 0.965 Contact Map
2cu3A 2 0.1774 34 0.969 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.