DTPD - ECOLI - GREMLIN Contacts

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DTPD - Dipeptide permease D

UniProt:	P75742	Sequences: MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSFLYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGYAQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVLLVATPALITILFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFFSMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKESVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAELFIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINYSINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13304
Length:	493 (463)
Sequences:	4697 (2986)
Seq/√Len:	138.8

ECOLI - DTPD DTPB YJDL DTPA
BACSU - YCLF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
161_A	173_L	4.113	1.00
361_I	386_V	3.403	1.00
363_T	461_Q	3.381	1.00
280_F	390_A	3.308	1.00
68_L	73_L	3.299	1.00
460_D	463_T	3.275	1.00
73_L	78_A	3.241	1.00
313_F	377_L	3.211	1.00
44_D	297_R	3.167	1.00
350_L	393_F	2.993	1.00
88_I	109_I	2.901	1.00
301_R	307_T	2.881	1.00
68_L	72_V	2.669	1.00
320_A	385_A	2.622	1.00
92_V	106_S	2.547	1.00
398_A	418_Y	2.515	1.00
92_V	109_I	2.488	1.00
473_V	477_W	2.486	1.00
162_Q	311_A	2.481	1.00
460_D	464_W	2.469	1.00
381_V	385_A	2.426	1.00
302_D	307_T	2.420	1.00
24_S	90_H	2.394	1.00
73_L	81_L	2.379	1.00
34_L	292_S	2.359	1.00
87_A	179_I	2.355	1.00
82_G	116_L	2.348	1.00
292_S	295_I	2.341	1.00
295_I	380_M	2.319	1.00
459_F	463_T	2.314	1.00
18_Q	22_Y	2.249	1.00
84_L	88_I	2.246	1.00
327_F	331_V	2.237	1.00
343_R	346_G	2.208	1.00
51_F	288_G	2.205	1.00
354_L	389_F	2.205	1.00
290_S	295_I	2.180	1.00
193_T	196_R	2.119	1.00
163_E	310_T	2.095	1.00
334_E	338_G	2.088	1.00
459_F	462_I	2.055	1.00
261_Q	265_K	2.052	1.00
80_M	186_L	2.047	1.00
21_E	118_K	2.045	1.00
204_R	207_N	2.040	1.00
140_F	403_T	2.035	1.00
93_L	106_S	2.014	1.00
25_F	55_C	1.992	1.00
76_R	189_N	1.990	1.00
324_C	389_F	1.973	1.00
281_W	395_D	1.945	1.00
361_I	382_L	1.940	1.00
94_G	175_A	1.923	1.00
33_I	37_T	1.919	1.00
353_G	472_L	1.914	1.00
18_Q	21_E	1.895	1.00
200_K	203_L	1.894	1.00
208_F	212_N	1.881	1.00
316_I	381_V	1.846	1.00
62_P	69_A	1.819	1.00
61_T	64_L	1.797	1.00
472_L	476_I	1.768	1.00
125_L	139_G	1.728	1.00
228_T	231_F	1.716	1.00
469_C	473_V	1.694	1.00
327_F	330_W	1.683	1.00
331_V	335_S	1.680	1.00
101_S	105_L	1.672	1.00
18_Q	118_K	1.668	1.00
42_Y	50_L	1.665	1.00
474_L	478_L	1.655	1.00
323_L	327_F	1.645	1.00
44_D	293_L	1.643	1.00
145_A	322_M	1.633	1.00
368_W	371_M	1.628	1.00
86_M	117_F	1.626	1.00
166_S	169_M	1.622	1.00
353_G	357_A	1.617	1.00
317_N	388_G	1.609	1.00
196_R	201_K	1.585	1.00
250_V	254_I	1.577	1.00
250_V	253_K	1.559	1.00
309_P	312_M	1.549	1.00
61_T	111_V	1.547	1.00
360_C	464_W	1.542	1.00
196_R	199_N	1.539	1.00
461_Q	464_W	1.529	1.00
251_L	254_I	1.528	1.00
242_V	246_I	1.517	1.00
91_V	175_A	1.514	1.00
189_N	194_H	1.503	1.00
122_S	419_M	1.501	1.00
89_G	110_I	1.497	1.00
38_N	167_W	1.495	1.00
212_N	216_L	1.489	1.00
199_N	207_N	1.485	1.00
152_I	322_M	1.478	1.00
34_L	310_T	1.458	1.00
253_K	256_R	1.455	1.00
357_A	386_V	1.438	1.00
317_N	321_V	1.437	1.00
277_S	422_S	1.425	1.00
143_M	147_G	1.425	1.00
256_R	259_E	1.419	1.00
159_G	311_A	1.412	1.00
43_N	46_H	1.409	1.00
203_L	207_N	1.408	1.00
169_M	172_G	1.405	1.00
302_D	305_G	1.404	1.00
480_Q	483_K	1.398	1.00
358_G	387_M	1.396	1.00
239_A	242_V	1.393	1.00
376_S	379_L	1.387	1.00
227_I	231_F	1.384	1.00
282_A	426_A	1.384	1.00
468_A	472_L	1.383	1.00
465_G	470_V	1.382	1.00
211_P	215_W	1.380	1.00
36_L	51_F	1.378	1.00
235_W	238_Y	1.358	1.00
100_P	104_Y	1.357	1.00
301_R	310_T	1.356	1.00
335_S	340_R	1.355	1.00
19_I	146_A	1.355	1.00
330_W	334_E	1.353	1.00
145_A	325_G	1.347	1.00
229_I	232_W	1.345	1.00
202_V	206_T	1.343	1.00
237_V	240_L	1.336	1.00
262_K	265_K	1.336	1.00
211_P	214_G	1.331	1.00
161_A	165_Y	1.329	1.00
375_S	379_L	1.319	1.00
176_V	180_A	1.298	1.00
362_L	383_G	1.297	1.00
367_R	371_M	1.294	1.00
356_S	469_C	1.292	1.00
459_F	464_W	1.289	1.00
320_A	388_G	1.286	1.00
87_A	91_V	1.285	1.00
292_S	296_D	1.281	1.00
158_C	161_A	1.271	1.00
106_S	110_I	1.270	1.00
198_V	201_K	1.259	1.00
462_I	465_G	1.257	1.00
49_E	435_D	1.255	1.00
13_Y	188_G	1.248	1.00
35_Y	96_S	1.246	1.00
33_I	47_A	1.242	1.00
284_A	287_G	1.238	1.00
27_G	158_C	1.231	1.00
366_A	369_S	1.230	1.00
206_T	210_L	1.226	1.00
127_E	403_T	1.224	1.00
89_G	93_L	1.222	1.00
472_L	475_M	1.222	1.00
442_F	445_S	1.221	1.00
279_L	471_G	1.214	1.00
354_L	390_A	1.201	1.00
321_V	391_E	1.201	1.00
204_R	208_F	1.201	1.00
201_K	206_T	1.196	1.00
144_Y	391_E	1.194	1.00
298_F	374_H	1.190	1.00
65_G	115_G	1.190	1.00
33_I	293_L	1.187	1.00
148_N	317_N	1.184	1.00
81_L	84_L	1.181	1.00
22_Y	118_K	1.180	1.00
480_Q	484_F	1.176	1.00
114_Y	118_K	1.174	0.99
89_G	113_G	1.171	0.99
157_A	173_L	1.171	0.99
412_G	416_G	1.168	0.99
207_N	260_N	1.164	0.99
19_I	149_V	1.152	0.99
342_V	350_L	1.151	0.99
114_Y	117_F	1.149	0.99
183_V	187_C	1.144	0.99
395_D	399_M	1.142	0.99
236_S	240_L	1.139	0.99
159_G	312_M	1.138	0.99
224_P	229_I	1.132	0.99
462_I	467_L	1.129	0.99
36_L	103_L	1.129	0.99
225_A	228_T	1.124	0.99
477_W	481_A	1.117	0.99
210_L	214_G	1.117	0.99
147_G	419_M	1.115	0.99
137_D	400_S	1.115	0.99
385_A	389_F	1.114	0.99
243_A	246_I	1.109	0.99
247_G	251_L	1.108	0.99
18_Q	143_M	1.106	0.99
301_R	309_P	1.105	0.99
214_G	218_V	1.103	0.99
348_F	394_I	1.101	0.99
129_Y	139_G	1.101	0.99
290_S	294_Y	1.099	0.99
118_K	419_M	1.096	0.99
199_N	203_L	1.093	0.99
365_S	379_L	1.090	0.99
87_A	182_L	1.088	0.99
75_N	127_E	1.087	0.99
86_M	114_Y	1.086	0.99
42_Y	100_P	1.082	0.99
20_W	177_G	1.082	0.99
478_L	481_A	1.075	0.99
240_L	243_A	1.068	0.99
207_N	211_P	1.065	0.99
201_K	207_N	1.064	0.99
122_S	143_M	1.063	0.99
224_P	228_T	1.062	0.99
468_A	475_M	1.059	0.99
151_S	318_A	1.057	0.99
58_V	61_T	1.056	0.99
221_V	226_L	1.055	0.99
200_K	208_F	1.055	0.99
96_S	102_F	1.054	0.99
21_E	26_Y	1.051	0.99
314_Q	318_A	1.051	0.99
22_Y	25_F	1.050	0.99
306_Y	312_M	1.050	0.99
251_L	255_Y	1.048	0.99
241_I	245_I	1.046	0.99
35_Y	103_L	1.045	0.99
203_L	212_N	1.042	0.99
243_A	247_G	1.041	0.99
328_L	331_V	1.037	0.99
218_V	222_A	1.035	0.99
237_V	241_I	1.034	0.99
73_L	77_M	1.034	0.99
238_Y	241_I	1.032	0.99
349_A	476_I	1.031	0.99
223_T	227_I	1.027	0.99
66_G	412_G	1.026	0.99
356_S	360_C	1.021	0.99
259_E	263_Q	1.018	0.99
144_Y	321_V	1.017	0.99
29_R	51_F	1.016	0.99
7_Q	11_I	1.015	0.99
287_G	387_M	1.012	0.98
18_Q	117_F	1.012	0.98
194_H	197_G	1.010	0.98
68_L	78_A	1.008	0.98
29_R	285_Q	1.007	0.98
227_I	230_L	1.005	0.98
202_V	205_A	1.004	0.98
43_N	47_A	1.001	0.98
255_Y	259_E	0.997	0.98
291_I	295_I	0.995	0.98
156_I	312_M	0.989	0.98
208_F	261_Q	0.987	0.98
231_F	235_W	0.985	0.98
122_S	415_T	0.984	0.98
147_G	399_M	0.978	0.98
282_A	429_L	0.977	0.98
349_A	472_L	0.975	0.98
58_V	111_V	0.972	0.98
235_W	240_L	0.971	0.98
172_G	176_V	0.971	0.98
187_C	190_R	0.971	0.98
226_L	231_F	0.970	0.98
346_G	479_Y	0.965	0.98
38_N	163_E	0.965	0.98
22_Y	26_Y	0.965	0.98
125_L	128_L	0.961	0.98
37_T	293_L	0.959	0.98
226_L	229_I	0.958	0.98
49_E	431_G	0.953	0.98
144_Y	148_N	0.950	0.98
247_G	250_V	0.944	0.98
126_G	403_T	0.943	0.98
223_T	229_I	0.940	0.98
470_V	473_V	0.936	0.98
256_R	260_N	0.932	0.97
160_Y	165_Y	0.931	0.97
356_S	472_L	0.930	0.97
229_I	233_K	0.930	0.97
61_T	115_G	0.926	0.97
470_V	477_W	0.924	0.97
395_D	418_Y	0.923	0.97
221_V	227_I	0.923	0.97
246_I	250_V	0.923	0.97
218_V	243_A	0.921	0.97
42_Y	46_H	0.920	0.97
228_T	233_K	0.917	0.97
299_V	380_M	0.917	0.97
209_L	212_N	0.915	0.97
351_G	394_I	0.915	0.97
468_A	471_G	0.914	0.97
469_C	472_L	0.913	0.97
52_S	430_A	0.913	0.97
364_L	368_W	0.913	0.97
215_W	218_V	0.913	0.97
291_I	383_G	0.911	0.97
200_K	210_L	0.911	0.97
472_L	480_Q	0.905	0.97
436_Q	440_A	0.905	0.97
287_G	391_E	0.903	0.97
321_V	326_V	0.903	0.97
199_N	202_V	0.902	0.97
325_G	396_P	0.900	0.97
461_Q	465_G	0.900	0.97
215_W	255_Y	0.897	0.97
215_W	222_A	0.895	0.97
244_T	247_G	0.889	0.97
284_A	388_G	0.889	0.97
224_P	227_I	0.888	0.97
207_N	210_L	0.887	0.97
37_T	44_D	0.887	0.97
59_Y	118_K	0.886	0.97
277_S	418_Y	0.884	0.96
66_G	416_G	0.884	0.96
34_L	38_N	0.882	0.96
212_N	215_W	0.880	0.96
239_A	243_A	0.880	0.96
208_F	211_P	0.876	0.96
295_I	299_V	0.874	0.96
330_W	333_K	0.869	0.96
300_N	374_H	0.869	0.96
15_V	146_A	0.868	0.96
172_G	175_A	0.860	0.96
335_S	342_V	0.858	0.96
223_T	226_L	0.858	0.96
160_Y	164_E	0.856	0.96
395_D	398_A	0.856	0.96
117_F	121_V	0.854	0.96
88_I	92_V	0.853	0.96
475_M	479_Y	0.852	0.96
122_S	399_M	0.850	0.96
324_C	392_L	0.850	0.96
324_C	327_F	0.849	0.96
153_I	156_I	0.849	0.96
20_W	23_F	0.848	0.96
246_I	249_G	0.848	0.96
50_L	104_Y	0.847	0.96
333_K	336_V	0.846	0.95
143_M	399_M	0.844	0.95
320_A	381_V	0.844	0.95
280_F	321_V	0.844	0.95
245_I	248_L	0.841	0.95
325_G	329_A	0.841	0.95
328_L	389_F	0.840	0.95
20_W	121_V	0.837	0.95
334_E	337_A	0.834	0.95
283_F	468_A	0.833	0.95
308_V	377_L	0.831	0.95
391_E	395_D	0.831	0.95
8_P	11_I	0.828	0.95
249_G	253_K	0.826	0.95
200_K	207_N	0.825	0.95
168_A	172_G	0.825	0.95
253_K	257_K	0.824	0.95
59_Y	419_M	0.821	0.95
357_A	361_I	0.816	0.95
205_A	208_F	0.814	0.94
206_T	209_L	0.814	0.94
227_I	233_K	0.807	0.94
19_I	147_G	0.807	0.94
122_S	147_G	0.802	0.94
46_H	49_E	0.801	0.94
284_A	395_D	0.799	0.94
224_P	230_L	0.799	0.94
209_L	213_W	0.798	0.94
57_L	428_Y	0.797	0.94
238_Y	247_G	0.796	0.94
63_I	416_G	0.795	0.94
208_F	215_W	0.795	0.94
336_V	341_T	0.793	0.94
335_S	338_G	0.793	0.94
80_M	83_A	0.791	0.94
94_G	172_G	0.789	0.93
21_E	178_M	0.788	0.93
308_V	312_M	0.788	0.93
354_L	386_V	0.784	0.93
324_C	385_A	0.784	0.93
349_A	475_M	0.781	0.93
85_L	112_C	0.780	0.93
463_T	468_A	0.780	0.93
316_I	320_A	0.778	0.93
87_A	175_A	0.775	0.93
400_S	404_R	0.774	0.93
213_W	216_L	0.770	0.93
336_V	339_N	0.770	0.93
348_F	398_A	0.769	0.93
217_L	220_L	0.768	0.93
138_G	329_A	0.768	0.93
193_T	197_G	0.766	0.92
22_Y	147_G	0.764	0.92
284_A	317_N	0.762	0.92
212_N	261_Q	0.760	0.92
401_Q	482_L	0.760	0.92
232_W	237_V	0.760	0.92
283_F	387_M	0.759	0.92
254_I	267_L	0.759	0.92
467_L	471_G	0.758	0.92
152_I	318_A	0.757	0.92
163_E	311_A	0.754	0.92
429_L	432_V	0.753	0.92
273_L	348_F	0.747	0.91
362_L	365_S	0.747	0.91
201_K	208_F	0.747	0.91
283_F	355_M	0.745	0.91
432_V	436_Q	0.742	0.91
21_E	25_F	0.739	0.91
143_M	391_E	0.737	0.91
346_G	349_A	0.736	0.91
274_T	402_I	0.735	0.91
291_I	384_L	0.730	0.91
225_A	229_I	0.729	0.90
239_A	246_I	0.728	0.90
345_W	479_Y	0.727	0.90
31_L	170_G	0.726	0.90
285_Q	427_N	0.726	0.90
361_I	383_G	0.725	0.90
332_V	336_V	0.725	0.90
121_V	147_G	0.723	0.90
33_I	48_Y	0.723	0.90
437_T	462_I	0.722	0.90
285_Q	423_G	0.722	0.90
437_T	441_S	0.722	0.90
70_D	74_G	0.720	0.90
426_A	429_L	0.718	0.90
228_T	232_W	0.717	0.90
98_I	102_F	0.717	0.90
280_F	394_I	0.716	0.90
126_G	140_F	0.715	0.90
287_G	358_G	0.712	0.89
48_Y	293_L	0.706	0.89
37_T	296_D	0.706	0.89
159_G	162_Q	0.705	0.89
90_H	178_M	0.704	0.89
287_G	384_L	0.704	0.89
204_R	212_N	0.703	0.89
157_A	160_Y	0.702	0.89
238_Y	242_V	0.702	0.89
317_N	391_E	0.702	0.89
162_Q	167_W	0.702	0.89
408_P	411_T	0.700	0.89
273_L	401_Q	0.700	0.89
143_M	406_E	0.699	0.89
270_I	402_I	0.699	0.89
248_L	251_L	0.699	0.89
370_A	373_G	0.698	0.88
278_M	426_A	0.698	0.88
363_T	366_A	0.697	0.88
34_L	297_R	0.696	0.88
236_S	239_A	0.696	0.88
67_F	72_V	0.695	0.88
155_P	315_S	0.694	0.88
338_G	341_T	0.693	0.88
299_V	377_L	0.692	0.88
200_K	206_T	0.691	0.88
79_V	185_F	0.689	0.88
281_W	284_A	0.687	0.88
230_L	235_W	0.686	0.88
80_M	182_L	0.686	0.88
444_A	470_V	0.685	0.88
48_Y	437_T	0.685	0.88
121_V	124_L	0.684	0.87
185_F	189_N	0.684	0.87
78_A	116_L	0.683	0.87
18_Q	147_G	0.682	0.87
77_M	81_L	0.677	0.87
198_V	202_V	0.675	0.87
209_L	228_T	0.672	0.87
160_Y	311_A	0.672	0.87
249_G	256_R	0.671	0.86
63_I	67_F	0.670	0.86
127_E	411_T	0.669	0.86
288_G	292_S	0.668	0.86
34_L	37_T	0.667	0.86
230_L	233_K	0.666	0.86
55_C	58_V	0.666	0.86
287_G	317_N	0.665	0.86
162_Q	165_Y	0.664	0.86
140_F	273_L	0.663	0.86
90_H	94_G	0.663	0.86
13_Y	191_H	0.661	0.86
202_V	208_F	0.660	0.86
301_R	377_L	0.660	0.86
21_E	286_Q	0.659	0.85
238_Y	244_T	0.657	0.85
224_P	231_F	0.657	0.85
199_N	206_T	0.656	0.85
230_L	236_S	0.656	0.85
119_S	123_C	0.654	0.85
65_G	129_Y	0.653	0.85
7_Q	129_Y	0.653	0.85
476_I	479_Y	0.652	0.85
334_E	339_N	0.652	0.85
33_I	292_S	0.650	0.85
156_I	315_S	0.650	0.85
221_V	228_T	0.649	0.85
355_M	358_G	0.648	0.85
18_Q	27_G	0.647	0.84
473_V	476_I	0.646	0.84
83_A	178_M	0.645	0.84
239_A	323_L	0.645	0.84
58_V	120_N	0.645	0.84
144_Y	317_N	0.644	0.84
473_V	481_A	0.643	0.84
64_L	426_A	0.642	0.84
25_F	118_K	0.642	0.84
215_W	219_L	0.641	0.84
409_G	416_G	0.640	0.84
120_N	412_G	0.640	0.84
193_T	199_N	0.637	0.83
122_S	395_D	0.636	0.83
433_I	462_I	0.635	0.83
31_L	36_L	0.634	0.83
80_M	84_L	0.633	0.83
117_F	120_N	0.633	0.83
148_N	151_S	0.633	0.83
332_V	341_T	0.632	0.83
140_F	406_E	0.632	0.83
152_I	319_F	0.632	0.83
282_A	433_I	0.632	0.83
15_V	19_I	0.631	0.83
226_L	230_L	0.630	0.83
471_G	474_L	0.627	0.83
148_N	395_D	0.626	0.82
142_L	145_A	0.626	0.82
336_V	340_R	0.625	0.82
94_G	182_L	0.625	0.82
212_N	241_I	0.625	0.82
35_Y	329_A	0.624	0.82
472_L	477_W	0.624	0.82
42_Y	104_Y	0.623	0.82
479_Y	482_L	0.623	0.82
224_P	232_W	0.622	0.82
337_A	340_R	0.621	0.82
123_C	415_T	0.620	0.82
293_L	296_D	0.619	0.82
434_A	437_T	0.619	0.82
148_N	318_A	0.619	0.82
363_T	367_R	0.618	0.82
69_A	79_V	0.618	0.82
328_L	392_L	0.617	0.82
474_L	477_W	0.617	0.82
293_L	297_R	0.616	0.81
9_R	12_Y	0.614	0.81
242_V	247_G	0.614	0.81
57_L	111_V	0.613	0.81
169_M	174_A	0.613	0.81
212_N	231_F	0.612	0.81
290_S	293_L	0.611	0.81
59_Y	148_N	0.611	0.81
207_N	212_N	0.610	0.81
212_N	217_L	0.608	0.81
349_A	353_G	0.607	0.80
7_Q	10_A	0.606	0.80
219_L	222_A	0.605	0.80
148_N	391_E	0.604	0.80
223_T	228_T	0.603	0.80
249_G	252_A	0.603	0.80
120_N	174_A	0.596	0.79
24_S	114_Y	0.596	0.79
365_S	375_S	0.595	0.79
30_A	155_P	0.594	0.79
60_V	427_N	0.593	0.79
22_Y	114_Y	0.593	0.79
286_Q	290_S	0.591	0.79
87_A	145_A	0.591	0.79
24_S	28_M	0.591	0.79
280_F	317_N	0.590	0.79
461_Q	475_M	0.590	0.79
253_K	258_A	0.589	0.78
91_V	95_A	0.587	0.78
141_S	329_A	0.585	0.78
203_L	206_T	0.585	0.78
83_A	174_A	0.584	0.78
217_L	223_T	0.581	0.78
12_Y	16_A	0.580	0.77
163_E	309_P	0.579	0.77
162_Q	166_S	0.577	0.77
54_Y	58_V	0.577	0.77
21_E	27_G	0.577	0.77
117_F	122_S	0.576	0.77
432_V	435_D	0.576	0.77
31_L	44_D	0.575	0.77
56_S	428_Y	0.575	0.77
23_F	156_I	0.574	0.77
363_T	463_T	0.573	0.77
130_E	193_T	0.570	0.76
124_L	128_L	0.570	0.76
260_N	263_Q	0.570	0.76
249_G	254_I	0.569	0.76
60_V	426_A	0.568	0.76
68_L	116_L	0.567	0.76
144_Y	147_G	0.566	0.76
372_Y	375_S	0.566	0.76
217_L	221_V	0.565	0.76
216_L	221_V	0.565	0.76
351_G	390_A	0.564	0.75
144_Y	314_Q	0.564	0.75
22_Y	27_G	0.564	0.75
216_L	219_L	0.564	0.75
52_S	431_G	0.563	0.75
281_W	426_A	0.563	0.75
218_V	221_V	0.562	0.75
10_A	13_Y	0.562	0.75
186_L	189_N	0.562	0.75
258_A	262_K	0.562	0.75
441_S	444_A	0.561	0.75
265_K	268_G	0.559	0.75
86_M	110_I	0.559	0.75
90_H	175_A	0.559	0.75
226_L	232_W	0.559	0.75
117_F	143_M	0.558	0.75
50_L	108_A	0.557	0.75
157_A	161_A	0.556	0.74
475_M	482_L	0.555	0.74
207_N	253_K	0.553	0.74
59_Y	317_N	0.552	0.74
220_L	224_P	0.552	0.74
283_F	463_T	0.551	0.74
477_W	480_Q	0.551	0.74
25_F	29_R	0.551	0.74
471_G	475_M	0.550	0.74
439_Q	443_D	0.549	0.73
236_S	243_A	0.549	0.73
239_A	247_G	0.549	0.73
97_E	100_P	0.548	0.73
319_F	323_L	0.544	0.73
205_A	264_R	0.543	0.73
85_L	106_S	0.542	0.73
18_Q	26_Y	0.541	0.72
227_I	232_W	0.540	0.72
18_Q	25_F	0.540	0.72
49_E	52_S	0.539	0.72
22_Y	143_M	0.539	0.72
306_Y	309_P	0.537	0.72
145_A	326_V	0.537	0.72
317_N	387_M	0.537	0.72
199_N	208_F	0.536	0.72
49_E	53_A	0.535	0.72
288_G	387_M	0.535	0.72
104_Y	108_A	0.535	0.72
35_Y	97_E	0.535	0.72
81_L	186_L	0.534	0.71
242_V	259_E	0.533	0.71
436_Q	439_Q	0.533	0.71
378_P	382_L	0.533	0.71
27_G	74_G	0.533	0.71
394_I	418_Y	0.532	0.71
250_V	255_Y	0.531	0.71
344_I	426_A	0.529	0.71
283_F	362_L	0.529	0.71
279_L	282_A	0.528	0.71
350_L	354_L	0.528	0.71
201_K	204_R	0.527	0.70
225_A	230_L	0.527	0.70
74_G	78_A	0.526	0.70
293_L	314_Q	0.526	0.70
165_Y	309_P	0.526	0.70
188_G	192_F	0.525	0.70
154_A	313_F	0.524	0.70
88_I	164_E	0.523	0.70
111_V	426_A	0.523	0.70
21_E	117_F	0.523	0.70
127_E	195_T	0.523	0.70
321_V	325_G	0.522	0.70
23_F	177_G	0.519	0.69
354_L	393_F	0.519	0.69
209_L	215_W	0.518	0.69
294_Y	299_V	0.518	0.69
360_C	363_T	0.518	0.69
40_L	460_D	0.518	0.69
129_Y	484_F	0.517	0.69
301_R	313_F	0.517	0.69
217_L	222_A	0.517	0.69
270_I	277_S	0.516	0.69
332_V	339_N	0.515	0.69
213_W	271_V	0.514	0.69
391_E	398_A	0.513	0.68
22_Y	178_M	0.512	0.68
167_W	171_F	0.512	0.68
351_G	355_M	0.511	0.68
225_A	231_F	0.510	0.68
26_Y	318_A	0.510	0.68
223_T	232_W	0.509	0.68
286_Q	359_F	0.508	0.68
10_A	14_V	0.507	0.68
86_M	90_H	0.506	0.67
365_S	383_G	0.505	0.67
276_F	352_L	0.505	0.67
38_N	296_D	0.505	0.67
137_D	347_K	0.504	0.67
188_G	191_H	0.502	0.67
118_K	122_S	0.502	0.67
200_K	212_N	0.501	0.67
65_G	120_N	0.500	0.66

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4oh3A	2	0.9655	100	0.52	Contact Map
4uvmA	1	0.9635	100	0.531	Contact Map
4q65A	1	0.8783	100	0.585	Contact Map
4tphA	2	0.8844	100	0.635	Contact Map
4ikvA	1	0.9432	100	0.64	Contact Map
4xnjA	1	0.9148	100	0.654	Contact Map
4w6vA	1	0.931	100	0.74	Contact Map
3wdoA	1	0.8093	99.9	0.776	Contact Map
2cfqA	1	0.8256	99.9	0.776	Contact Map
1pw4A	1	0.8256	99.9	0.785	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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