GREMLIN Database
YAHN - Uncharacterized membrane protein YahN
UniProt: P75693 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13598
Length: 223 (198)
Sequences: 12900 (9234)
Seq/√Len: 656.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
62_L128_F5.1001.00
101_A209_G3.5501.00
102_W106_R3.4541.00
20_V168_G3.1701.00
199_V202_R2.9471.00
87_S90_R2.7621.00
98_L212_A2.6731.00
125_Y129_R2.5301.00
55_L124_W2.3561.00
198_R202_R2.3331.00
66_F132_L2.2651.00
162_R166_W2.2551.00
91_I95_A2.2101.00
99_W103_C2.1351.00
94_G216_I2.1331.00
45_S53_G2.0701.00
105_M202_R2.0541.00
105_M205_G2.0361.00
206_A210_V1.9971.00
40_V56_T1.9761.00
26_L148_I1.8941.00
103_C106_R1.8801.00
98_L209_G1.8631.00
101_A205_G1.8321.00
24_V172_A1.8141.00
84_E87_S1.8061.00
63_G136_L1.7691.00
44_T48_S1.7271.00
108_Q202_R1.7241.00
94_G212_A1.7121.00
53_G181_S1.6891.00
52_A127_F1.6741.00
38_L180_L1.6521.00
86_F90_R1.6021.00
37_N60_V1.5961.00
129_R133_I1.5551.00
31_F172_A1.5181.00
24_V168_G1.4861.00
77_T81_Q1.4851.00
32_F176_W1.4641.00
98_L102_W1.4631.00
87_S91_I1.4511.00
45_S181_S1.4291.00
65_A170_V1.4161.00
42_V184_F1.4051.00
58_L128_F1.3961.00
109_S202_R1.3941.00
57_G181_S1.3901.00
44_T56_T1.3861.00
188_A192_A1.3811.00
132_L136_L1.3641.00
128_F132_L1.3481.00
199_V203_V1.3481.00
84_E88_L1.3331.00
88_L92_V1.3241.00
54_V182_Q1.3201.00
56_T131_G1.3061.00
53_G57_G1.3031.00
173_S177_R1.2751.00
91_I94_G1.2721.00
186_L189_V1.2651.00
196_M199_V1.2551.00
126_V129_R1.2391.00
145_F169_I1.2221.00
96_Y100_F1.2171.00
123_P126_V1.2151.00
50_R185_S1.2031.00
193_Y196_M1.1951.00
21_Y25_G1.1941.00
50_R182_Q1.1941.00
19_A22_L1.1871.00
101_A212_A1.1801.00
195_R199_V1.1731.00
91_I216_I1.1721.00
158_P161_A1.1701.00
66_F136_L1.1571.00
209_G213_L1.1381.00
205_G209_G1.1341.00
69_G73_F1.1331.00
51_R55_L1.1231.00
22_L25_G1.1181.00
154_N157_T1.1131.00
61_A170_V1.1121.00
40_V134_T1.1071.00
48_S52_A1.1051.00
179_F183_A1.0921.00
106_R109_S1.0811.00
44_T130_R1.0741.00
61_A174_I1.0731.00
23_T27_F1.0731.00
107_R201_S1.0711.00
40_V44_T1.0621.00
54_V178_V1.0581.00
22_L26_L1.0501.00
31_F173_S1.0461.00
59_G128_F1.0421.00
202_R206_A1.0371.00
41_V45_S1.0351.00
27_F169_I1.0221.00
43_Q47_A1.0121.00
47_A51_R1.0111.00
37_N134_T1.0031.00
41_V177_R1.0031.00
63_G132_L1.0001.00
176_W180_L0.9991.00
37_N135_D0.9971.00
126_V130_R0.9921.00
96_Y99_W0.9831.00
74_G79_I0.9821.00
28_V172_A0.9661.00
210_V214_R0.9641.00
64_D135_D0.9591.00
195_R198_R0.9581.00
38_L177_R0.9501.00
46_L184_F0.9471.00
64_D141_T0.9411.00
122_A126_V0.9221.00
37_N173_S0.9201.00
203_V206_A0.9171.00
133_I137_S0.9061.00
163_L166_W0.8991.00
159_T162_R0.8961.00
41_V181_S0.8831.00
79_I82_C0.8821.00
24_V28_V0.8811.00
62_L132_L0.8811.00
154_N162_R0.8751.00
54_V181_S0.8731.00
197_Q201_S0.8691.00
186_L190_R0.8651.00
160_W163_L0.8621.00
26_L29_I0.8451.00
67_Y142_V0.8421.00
74_G81_Q0.8421.00
50_R181_S0.8381.00
213_L217_Y0.8361.00
192_A196_M0.8341.00
51_R124_W0.8331.00
39_F204_I0.8281.00
20_V171_L0.8181.00
39_F43_Q0.8171.00
109_S112_Q0.8171.00
209_G212_A0.8161.00
37_N64_D0.8151.00
178_V182_Q0.8131.00
50_R178_V0.8131.00
103_C107_R0.8111.00
92_V95_A0.8041.00
25_G29_I0.8021.00
162_R165_A0.8001.00
174_I178_V0.7971.00
67_Y136_L0.7941.00
183_A186_L0.7901.00
52_A55_L0.7861.00
158_P162_R0.7831.00
121_S125_Y0.7831.00
21_Y24_V0.7821.00
105_M209_G0.7811.00
190_R196_M0.7791.00
38_L42_V0.7771.00
64_D67_Y0.7731.00
104_S205_G0.7711.00
59_G132_L0.7701.00
99_W102_W0.7661.00
147_S151_V0.7631.00
68_S145_F0.7611.00
94_G98_L0.7611.00
73_F77_T0.7601.00
184_F187_P0.7601.00
111_P114_S0.7571.00
82_C85_I0.7561.00
61_A173_S0.7561.00
76_A80_T0.7521.00
95_A98_L0.7491.00
157_T162_R0.7481.00
127_F130_R0.7441.00
157_T161_A0.7421.00
203_V207_I0.7411.00
57_G178_V0.7391.00
27_F31_F0.7331.00
38_L176_W0.7321.00
85_I88_L0.7301.00
18_H21_Y0.7271.00
29_I33_N0.7261.00
102_W209_G0.7251.00
41_V56_T0.7231.00
106_R110_T0.7201.00
55_L127_F0.7181.00
67_Y141_T0.7171.00
64_D170_V0.7161.00
83_E87_S0.7131.00
20_V24_V0.7081.00
188_A191_R0.7071.00
182_Q186_L0.7051.00
189_V192_A0.7031.00
57_G61_A0.7011.00
112_Q115_T0.7001.00
68_S177_R0.6981.00
190_R193_Y0.6971.00
200_A204_I0.6941.00
37_N177_R0.6931.00
109_S198_R0.6911.00
41_V60_V0.6901.00
31_F176_W0.6851.00
45_S184_F0.6781.00
137_S146_I0.6781.00
82_C86_F0.6761.00
62_L66_F0.6741.00
38_L134_T0.6741.00
60_V64_D0.6671.00
26_L30_T0.6671.00
95_A99_W0.6661.00
18_H22_L0.6661.00
42_V180_L0.6621.00
48_S127_F0.6621.00
31_F38_L0.6601.00
67_Y71_G0.6571.00
67_Y135_D0.6531.00
54_V57_G0.6511.00
44_T47_A0.6471.00
52_A124_W0.6471.00
214_R217_Y0.6451.00
92_V137_S0.6421.00
56_T127_F0.6391.00
177_R180_L0.6371.00
124_W128_F0.6361.00
101_A105_M0.6301.00
77_T80_T0.6281.00
160_W164_M0.6281.00
66_F69_G0.6271.00
175_I179_F0.6221.00
88_L91_I0.6161.00
196_M200_A0.6131.00
68_S170_V0.6111.00
31_F177_R0.6071.00
190_R194_G0.6061.00
67_Y146_I0.6051.00
161_A165_A0.6051.00
33_N38_L0.6031.00
64_D173_S0.6021.00
118_Q121_S0.6011.00
142_V146_I0.6011.00
71_G76_A0.6001.00
58_L61_A0.6001.00
71_G145_F0.5971.00
60_V135_D0.5891.00
170_V174_I0.5871.00
171_L175_I0.5841.00
43_Q201_S0.5841.00
108_Q111_P0.5791.00
71_G142_V0.5771.00
121_S124_W0.5751.00
64_D145_F0.5731.00
41_V57_G0.5721.00
63_G135_D0.5711.00
28_V32_F0.5681.00
130_R134_T0.5671.00
49_G52_A0.5611.00
93_G143_L0.5601.00
135_D141_T0.5601.00
31_F64_D0.5591.00
67_Y76_A0.5581.00
98_L216_I0.5581.00
176_W179_F0.5581.00
48_S122_A0.5521.00
125_Y128_F0.5481.00
64_D169_I0.5471.00
54_V58_L0.5471.00
135_D177_R0.5451.00
36_A104_S0.5411.00
81_Q84_E0.5401.00
56_T134_T0.5371.00
141_T146_I0.5361.00
89_I93_G0.5361.00
103_C130_R0.5351.00
34_P140_Q0.5310.99
33_N201_S0.5290.99
105_M206_A0.5270.99
27_F168_G0.5270.99
167_A171_L0.5240.99
165_A168_G0.5230.99
210_V213_L0.5220.99
31_F141_T0.5200.99
61_A177_R0.5180.99
206_A209_G0.5180.99
105_M109_S0.5130.99
108_Q198_R0.5130.99
30_T148_I0.5130.99
153_L163_L0.5120.99
82_C87_S0.5090.99
158_P163_L0.5090.99
53_G56_T0.5080.99
183_A187_P0.5040.99
177_R181_S0.5030.99
169_I173_S0.5020.99
145_F173_S0.5010.99
37_N141_T0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j1zP 8 0.4709 16.4 0.94 Contact Map
2cfqA 1 0.9193 9.9 0.946 Contact Map
3h90A 3 0.4305 7.8 0.948 Contact Map
2h3oA 1 0.1973 6.4 0.95 Contact Map
4p6vD 1 0.4395 4.6 0.954 Contact Map
4xnjA 1 0.426 4.1 0.955 Contact Map
3wdoA 1 0.4305 3.9 0.955 Contact Map
3udcA 3 0.3094 3.9 0.955 Contact Map
4ikvA 1 0.4798 3.6 0.956 Contact Map
2wdqD 2 0.139 3.4 0.956 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0077 seconds.