GREMLIN Database
YAGP - Uncharacterized protein YagP
UniProt: P75684 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13555
Length: 136 (129)
Sequences: 16527 (12716)
Seq/√Len: 1119.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
71_L87_Y3.2171.00
70_A77_T3.0801.00
26_K57_Q3.0071.00
67_L87_Y2.7751.00
95_S98_D2.7701.00
15_E94_V2.7341.00
13_R26_K2.4591.00
87_Y92_K2.4191.00
9_L25_H2.3621.00
109_L125_I2.1721.00
3_A43_F2.1311.00
19_A100_F2.0671.00
27_C41_W2.0481.00
85_R89_E2.0301.00
71_L92_K1.9781.00
17_F21_G1.8591.00
67_L71_L1.8231.00
6_V73_G1.6911.00
18_L21_G1.6911.00
45_E48_R1.6641.00
28_I66_M1.6441.00
8_I73_G1.5961.00
10_A96_L1.5631.00
4_P84_F1.5561.00
5_V10_A1.5551.00
40_R51_D1.5511.00
87_Y90_S1.5511.00
58_I69_L1.5321.00
10_A15_E1.5231.00
4_P88_I1.5011.00
86_P90_S1.4961.00
9_L26_K1.4691.00
3_A76_I1.4661.00
79_A84_F1.3891.00
68_R72_A1.3841.00
20_S50_F1.3801.00
27_C54_I1.3791.00
2_P95_S1.3511.00
127_Y131_W1.3331.00
81_Q85_R1.3151.00
60_T66_M1.2981.00
44_E49_T1.2971.00
45_E100_F1.2881.00
40_R53_A1.2551.00
42_P51_D1.2371.00
25_H76_I1.2371.00
2_P81_Q1.2341.00
21_G24_T1.2261.00
124_L128_V1.2171.00
69_L74_G1.2161.00
76_I96_L1.1911.00
8_I11_A1.1751.00
29_G56_P1.1671.00
42_P49_T1.1631.00
117_I122_R1.1541.00
45_E50_F1.1541.00
5_V76_I1.1491.00
8_I12_G1.1431.00
3_A78_I1.1371.00
4_P77_T1.1161.00
126_D129_K1.1081.00
123_A127_Y1.0841.00
88_I95_S1.0761.00
122_R126_D1.0721.00
10_A14_G1.0641.00
26_K56_P1.0541.00
70_A93_L1.0341.00
28_I75_G1.0331.00
111_F117_I1.0231.00
119_P123_A1.0201.00
60_T65_L1.0201.00
20_S23_N0.9981.00
86_P89_E0.9851.00
97_L100_F0.9831.00
95_S101_L0.9831.00
66_M77_T0.9641.00
117_I121_L0.9551.00
123_A126_D0.9491.00
10_A94_V0.9421.00
31_R59_T0.9401.00
111_F125_I0.9211.00
68_R71_L0.9131.00
81_Q95_S0.9071.00
84_F88_I0.8891.00
9_L13_R0.8881.00
62_D65_L0.8871.00
80_T83_T0.8631.00
63_L79_A0.8541.00
11_A94_V0.8451.00
84_F87_Y0.8391.00
78_I102_P0.8371.00
45_E99_D0.8341.00
27_C56_P0.8261.00
23_N52_L0.8201.00
92_K95_S0.8111.00
63_L80_T0.8111.00
30_W63_L0.8081.00
114_R117_I0.8051.00
7_L11_A0.7971.00
79_A83_T0.7951.00
3_A97_L0.7911.00
15_E98_D0.7891.00
121_L125_I0.7731.00
13_R25_H0.7721.00
16_C25_H0.7661.00
113_Q117_I0.7591.00
44_E103_Q0.7551.00
13_R16_C0.7501.00
30_W66_M0.7481.00
6_V71_L0.7471.00
118_A121_L0.7351.00
29_G54_I0.7231.00
22_G76_I0.7221.00
10_A16_C0.7201.00
69_L79_A0.7181.00
60_T69_L0.7181.00
125_I129_K0.7151.00
111_F114_R0.6941.00
67_L79_A0.6811.00
122_R125_I0.6671.00
119_P122_R0.6521.00
9_L76_I0.6511.00
23_N55_E0.6491.00
109_L121_L0.6461.00
109_L129_K0.6401.00
23_N53_A0.6391.00
28_I70_A0.6391.00
65_L68_R0.6381.00
82_E105_P0.6361.00
10_A76_I0.6321.00
19_A23_N0.6321.00
14_G25_H0.6251.00
113_Q116_N0.6231.00
44_E101_L0.6231.00
31_R38_P0.6201.00
84_F93_L0.6201.00
19_A43_F0.6181.00
66_M83_T0.6151.00
18_L50_F0.6141.00
109_L128_V0.6121.00
50_F53_A0.6101.00
2_P88_I0.6081.00
126_D130_E0.6021.00
80_T107_F0.6021.00
69_L83_T0.6001.00
30_W62_D0.6001.00
68_R87_Y0.5951.00
39_Y42_P0.5951.00
18_L100_F0.5921.00
64_R83_T0.5921.00
16_C21_G0.5901.00
13_R24_T0.5891.00
7_L94_V0.5871.00
33_S37_A0.5821.00
88_I91_G0.5801.00
44_E48_R0.5791.00
111_F121_L0.5771.00
33_S36_V0.5741.00
111_F124_L0.5701.00
36_V39_Y0.5701.00
123_A128_V0.5651.00
63_L83_T0.5651.00
50_F54_I0.5651.00
26_K55_E0.5541.00
86_P92_K0.5501.00
44_E100_F0.5501.00
120_K124_L0.5501.00
127_Y130_E0.5471.00
30_W80_T0.5461.00
98_D101_L0.5451.00
128_V131_W0.5371.00
30_W61_N0.5341.00
77_T84_F0.5331.00
16_C97_L0.5331.00
26_K74_G0.5331.00
32_Q80_T0.5321.00
105_P108_Y0.5311.00
4_P93_L0.5311.00
17_F99_D0.5281.00
29_G39_Y0.5271.00
120_K123_A0.5271.00
19_A97_L0.5241.00
62_D83_T0.5221.00
124_L131_W0.5211.00
29_G32_Q0.5191.00
69_L75_G0.5161.00
118_A123_A0.5151.00
65_L69_L0.5131.00
81_Q88_I0.5101.00
82_E107_F0.5051.00
29_G59_T0.5041.00
63_L105_P0.5031.00
28_I77_T0.5021.00
110_Y118_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3hhgA 3 0.9706 99.8 0.494 Contact Map
3mz1A 2 1 99.8 0.496 Contact Map
3szpA 3 0.9412 99.7 0.522 Contact Map
3fd3A 2 0.9485 99.7 0.55 Contact Map
1al3A 1 0.9706 99.6 0.572 Contact Map
3hhfB 2 0.9559 99.6 0.572 Contact Map
3ispA 3 0.9412 99.6 0.578 Contact Map
3fzvA 4 0.9485 99.6 0.58 Contact Map
3kosA 2 0.9412 99.6 0.582 Contact Map
2qsxA 2 0.875 99.6 0.585 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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