GREMLIN Database
FBPB - Putative ferric transport system permease protein FbpB (Fragment)
UniProt: P75681 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14277
Length: 115 (102)
Sequences: 14580 (8076)
Seq/√Len: 799.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
11_S21_T3.5541.00
20_R24_H3.5191.00
19_L23_T3.0871.00
8_D26_L2.7911.00
75_E78_V2.6391.00
17_G20_R2.5631.00
20_R23_T2.5251.00
16_A20_R2.4031.00
95_F99_W2.2141.00
11_S16_A2.2051.00
16_A24_H2.1401.00
12_L18_S1.9791.00
6_S9_E1.9081.00
18_S21_T1.7951.00
66_Y69_N1.7041.00
49_V68_L1.6711.00
66_Y70_R1.6611.00
7_L29_L1.6331.00
10_A13_S1.6011.00
61_R66_Y1.5711.00
5_K9_E1.5631.00
66_Y82_Y1.5231.00
30_L33_A1.5101.00
61_R69_N1.4781.00
12_L21_T1.4171.00
52_I62_V1.3971.00
17_G21_T1.3891.00
8_D21_T1.3631.00
70_R78_V1.3131.00
37_A41_S1.2991.00
11_S25_I1.2491.00
49_V53_V1.2391.00
3_I29_L1.2201.00
5_K8_D1.2111.00
31_R35_L1.2061.00
97_F101_I1.2011.00
33_A37_A1.1871.00
95_F98_D1.1701.00
48_T52_I1.1481.00
56_V65_A1.1171.00
43_V47_T1.1131.00
98_D101_I1.1081.00
96_I99_W1.0871.00
92_A96_I1.0771.00
62_V65_A1.0721.00
8_D12_L1.0691.00
61_R65_A1.0611.00
26_L30_L1.0571.00
27_L34_I1.0271.00
91_L95_F1.0261.00
3_I30_L1.0011.00
70_R75_E0.9961.00
71_V79_A0.9881.00
53_V68_L0.9861.00
23_T27_L0.9441.00
99_W102_G0.9321.00
21_T25_I0.9191.00
16_A21_T0.8951.00
77_G81_A0.8811.00
44_R47_T0.8811.00
67_I83_G0.8771.00
63_A82_Y0.8771.00
76_Y80_I0.8761.00
101_I104_S0.8751.00
41_S45_A0.8741.00
31_R104_S0.8651.00
10_A16_A0.8611.00
99_W103_E0.8571.00
22_I26_L0.8551.00
56_V61_R0.8541.00
52_I56_V0.8371.00
67_I82_Y0.8301.00
75_E79_A0.8241.00
86_L90_M0.8221.00
27_L31_R0.8221.00
47_T50_S0.8141.00
26_L29_L0.8081.00
31_R34_I0.8051.00
56_V60_T0.7991.00
98_D102_G0.7821.00
31_R103_E0.7811.00
7_L25_I0.7731.00
42_F93_I0.7731.00
18_S22_I0.7531.00
46_I86_L0.7501.00
17_G23_T0.7431.00
50_S60_T0.7361.00
47_T64_T0.7251.00
69_N72_E0.7241.00
78_V81_A0.7221.00
3_I26_L0.7211.00
51_A55_L0.7201.00
22_I27_L0.7121.00
72_E76_Y0.7111.00
90_M93_I0.7071.00
70_R73_D0.7041.00
92_A99_W0.6761.00
88_V92_A0.6691.00
30_L34_I0.6691.00
53_V65_A0.6651.00
57_T60_T0.6651.00
4_D7_L0.6601.00
48_T51_A0.6501.00
96_I100_L0.6501.00
73_D76_Y0.6391.00
94_I98_D0.6351.00
47_T51_A0.6331.00
81_A84_S0.6321.00
36_S97_F0.6311.00
21_T24_H0.6311.00
9_E12_L0.6291.00
48_T64_T0.6221.00
50_S79_A0.6201.00
52_I64_T0.6141.00
93_I101_I0.6061.00
58_P69_N0.5981.00
43_V93_I0.5951.00
77_G80_I0.5941.00
93_I96_I0.5881.00
10_A25_I0.5841.00
63_A85_I0.5831.00
65_A69_N0.5811.00
84_S88_V0.5801.00
100_L104_S0.5781.00
92_A95_F0.5741.00
90_M94_I0.5691.00
31_R100_L0.5671.00
43_V94_I0.5631.00
83_G86_L0.5591.00
44_R64_T0.5581.00
64_T68_L0.5561.00
98_D104_S0.5501.00
55_L81_A0.5451.00
51_A56_V0.5441.00
82_Y86_L0.5431.00
44_R50_S0.5411.00
50_S53_V0.5381.00
12_L17_G0.5341.00
39_I97_F0.5341.00
50_S68_L0.5301.00
60_T65_A0.5271.00
35_L38_L0.5251.00
63_A86_L0.5251.00
74_G77_G0.5231.00
64_T82_Y0.5181.00
64_T86_L0.5101.00
21_T26_L0.5081.00
60_T71_V0.5081.00
49_V54_F0.5071.00
55_L71_V0.5071.00
38_L41_S0.5031.00
50_S90_M0.5011.00
97_F100_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2onkC 2 0.8783 99.7 0.329 Contact Map
3d31C 2 0.8435 99.7 0.332 Contact Map
4tquM 1 0.9217 99.7 0.366 Contact Map
3rlfF 1 0.8261 99.6 0.386 Contact Map
3rlfG 1 0.9652 99.6 0.406 Contact Map
4ymuD 2 0.9043 99.6 0.417 Contact Map
4tquN 1 0.887 99.6 0.419 Contact Map
3tuiA 2 0.8957 99.5 0.452 Contact Map
2kluA 1 0.3739 14.6 0.898 Contact Map
4mrsA 2 0.8348 11.8 0.902 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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