GREMLIN Database
YKFJ - Putative uncharacterized protein YkfJ
UniProt: P75675 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14368
Length: 88 (72)
Sequences: 148 (79)
Seq/√Len: 9.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
58_Y73_A2.3920.78
22_D44_Q2.3190.76
34_L83_R2.2710.74
16_V54_P2.0900.68
42_N68_G2.0230.65
43_M64_F1.9970.64
42_N69_R1.8800.59
35_H39_N1.7430.53
56_R64_F1.6340.48
18_T31_I1.6320.48
49_M60_I1.6000.47
66_S70_F1.5810.46
34_L84_N1.5770.46
25_W56_R1.5690.45
43_M62_A1.5630.45
40_L71_Y1.4770.41
19_I48_G1.4180.39
49_M73_A1.4140.39
29_L54_P1.4080.38
37_T43_M1.3800.37
21_S27_E1.3520.36
74_R80_A1.3440.36
60_I63_A1.3420.36
42_N70_F1.3210.35
21_S78_N1.2860.33
15_A60_I1.2690.33
54_P60_I1.2530.32
66_S69_R1.2520.32
57_G62_A1.2330.31
57_G64_F1.2060.30
58_Y65_F1.1810.29
27_E56_R1.1790.29
18_T28_S1.1480.28
37_T57_G1.1360.28
32_Q36_T1.1150.27
17_F41_P1.0800.26
67_V76_R1.0530.25
57_G66_S1.0480.25
49_M83_R1.0400.25
13_S22_D1.0340.24
78_N85_G1.0330.24
16_V21_S1.0110.24
56_R65_F0.9950.23
43_M57_G0.9750.22
23_D67_V0.9400.21
32_Q35_H0.9290.21
33_Q55_G0.9240.21
36_T66_S0.9220.21
44_Q67_V0.9160.21
56_R78_N0.9010.20
28_S32_Q0.8920.20
17_F76_R0.8920.20
16_V46_V0.8870.20
22_D63_A0.8620.19
27_E71_Y0.8390.19
20_A24_L0.8350.18
39_N45_R0.8250.18
25_W78_N0.8210.18
71_Y80_A0.8160.18
27_E78_N0.8140.18
32_Q73_A0.8030.18
24_L78_N0.7990.18
24_L73_A0.7910.17
14_D17_F0.7800.17
28_S73_A0.7750.17
19_I26_I0.7720.17
37_T40_L0.7700.17
32_Q85_G0.7690.17
15_A85_G0.7600.17
23_D76_R0.7530.16
37_T56_R0.7520.16
44_Q68_G0.7490.16
79_G82_N0.7300.16
18_T22_D0.7290.16
35_H45_R0.7260.16
26_I29_L0.7200.16
21_S25_W0.7180.16
45_R63_A0.7120.15
35_H84_N0.7060.15
52_L80_A0.6930.15
34_L49_M0.6910.15
80_A84_N0.6870.15
65_F70_F0.6580.14
43_M78_N0.6480.14
30_A83_R0.6410.14
67_V71_Y0.6320.14
46_V65_F0.6310.14
35_H38_A0.6300.14
14_D21_S0.5830.13
32_Q65_F0.5790.13
24_L46_V0.5770.13
65_F73_A0.5710.12
20_A58_Y0.5690.12
39_N59_P0.5670.12
41_P70_F0.5570.12
56_R69_R0.5570.12
37_T64_F0.5540.12
22_D47_V0.5540.12
19_I47_V0.5490.12
30_A34_L0.5370.12
37_T62_A0.5340.12
35_H67_V0.5300.12
29_L42_N0.5290.12
13_S32_Q0.5250.12
41_P54_P0.5210.12
29_L39_N0.5060.11
79_G83_R0.5030.11
18_T23_D0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4dwrB 3 0.9886 99.9 0.502 Contact Map
2epgA 1 0.9773 99.9 0.507 Contact Map
3futA 1 0.5568 29.1 0.928 Contact Map
4iscA 1 0.6477 12.9 0.939 Contact Map
4o6dA 2 0.1932 12.3 0.939 Contact Map
3cvoA 4 0.375 10.1 0.941 Contact Map
3tqsA 1 0.3636 10.1 0.942 Contact Map
4jxjA 1 0.3636 10 0.942 Contact Map
3x0dA 1 0.5682 9.5 0.942 Contact Map
4rwzA 1 0.4432 9.4 0.942 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0047 seconds.