WCAJ - ECOLI - GREMLIN Contacts

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WCAJ - UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase

UniProt:	P71241	Sequences: MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSVIFSAGLVAFNNDFDTQLKIWLAWYALTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLMESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVVPLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13575
Length:	464 (435)
Sequences:	4358 (3500)
Seq/√Len:	167.8

ECOLI - WCAJ
BACSU - EPSL
HALSA - Q9HSZ7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
296_I	361_L	5.564	1.00
299_A	352_V	5.418	1.00
329_S	356_L	5.186	1.00
275_R	279_I	4.994	1.00
286_L	368_I	4.500	1.00
303_S	351_K	4.497	1.00
313_T	321_P	4.326	1.00
313_T	323_K	4.087	1.00
370_V	408_I	4.007	1.00
311_R	323_K	3.746	1.00
429_K	432_E	3.651	1.00
277_E	281_L	3.515	1.00
296_I	356_L	3.500	1.00
377_I	450_V	3.386	1.00
355_F	359_T	3.316	1.00
295_C	299_A	2.906	1.00
100_A	109_L	2.850	1.00
89_T	116_Y	2.732	1.00
307_P	332_V	2.589	1.00
146_M	172_E	2.540	1.00
411_W	415_N	2.500	1.00
301_K	308_V	2.496	1.00
283_T	371_L	2.450	1.00
367_F	377_I	2.423	1.00
333_M	337_K	2.395	1.00
300_V	303_S	2.383	1.00
281_L	377_I	2.370	1.00
315_Y	321_P	2.325	1.00
282_A	286_L	2.293	1.00
285_I	289_I	2.279	1.00
311_R	325_W	2.256	1.00
309_I	325_W	2.248	1.00
297_A	308_V	2.235	1.00
367_F	408_I	2.093	1.00
333_M	336_D	2.080	1.00
352_V	356_L	2.065	1.00
282_A	371_L	2.058	1.00
448_K	452_L	2.030	1.00
301_K	306_G	2.025	1.00
207_N	235_L	2.016	1.00
177_Y	199_D	1.997	1.00
436_E	440_E	1.980	1.00
337_K	340_T	1.976	1.00
345_N	354_N	1.939	1.00
383_H	387_H	1.928	1.00
384_A	387_H	1.912	1.00
289_I	293_L	1.911	1.00
293_L	309_I	1.902	1.00
290_S	294_C	1.849	1.00
391_Y	427_M	1.848	1.00
146_M	206_H	1.844	1.00
331_K	337_K	1.841	1.00
277_E	443_V	1.832	1.00
279_I	282_A	1.828	1.00
325_W	372_T	1.811	1.00
24_S	126_C	1.792	1.00
199_D	203_G	1.776	1.00
356_L	361_L	1.773	1.00
315_Y	388_N	1.773	1.00
103_N	109_L	1.769	1.00
368_I	372_T	1.768	1.00
198_E	202_A	1.742	1.00
383_H	391_Y	1.727	1.00
148_A	177_Y	1.725	1.00
378_V	409_T	1.721	1.00
32_G	122_G	1.717	1.00
298_L	302_L	1.717	1.00
286_L	290_S	1.715	1.00
294_C	298_L	1.709	1.00
144_K	172_E	1.705	1.00
296_I	327_F	1.682	1.00
32_G	36_V	1.667	1.00
147_V	171_F	1.644	1.00
356_L	359_T	1.636	1.00
285_I	377_I	1.630	1.00
387_H	391_Y	1.630	1.00
349_V	354_N	1.619	1.00
358_R	460_N	1.603	1.00
293_L	327_F	1.599	1.00
149_V	160_M	1.593	1.00
341_Q	387_H	1.592	1.00
160_M	176_V	1.578	1.00
281_L	285_I	1.566	1.00
175_G	191_G	1.551	1.00
285_I	367_F	1.535	1.00
40_S	109_L	1.524	1.00
192_N	195_Q	1.523	1.00
103_N	108_Q	1.516	1.00
331_K	347_P	1.509	1.00
40_S	110_K	1.506	1.00
63_G	68_F	1.493	1.00
283_T	287_L	1.490	1.00
289_I	292_V	1.487	1.00
411_W	436_E	1.461	1.00
383_H	427_M	1.459	1.00
383_H	388_N	1.459	1.00
342_A	387_H	1.454	1.00
278_D	376_S	1.454	1.00
385_V	389_E	1.444	1.00
279_I	283_T	1.443	1.00
195_Q	198_E	1.442	1.00
149_V	156_G	1.410	1.00
291_P	294_C	1.409	1.00
153_L	156_G	1.403	1.00
310_F	335_N	1.384	1.00
80_E	131_R	1.380	1.00
316_G	406_P	1.367	1.00
412_A	419_G	1.364	1.00
252_E	255_G	1.360	1.00
36_V	40_S	1.358	1.00
364_L	367_F	1.355	1.00
383_H	430_R	1.334	1.00
325_W	369_N	1.331	1.00
404_V	438_I	1.322	1.00
411_W	440_E	1.308	1.00
360_S	418_R	1.298	1.00
420_E	426_K	1.287	1.00
427_M	430_R	1.279	1.00
367_F	450_V	1.278	1.00
384_A	427_M	1.275	1.00
419_G	430_R	1.267	1.00
290_S	293_L	1.266	1.00
342_A	412_A	1.253	1.00
138_R	141_G	1.253	1.00
452_L	456_K	1.244	1.00
29_M	119_T	1.238	1.00
275_R	282_A	1.235	1.00
156_G	176_V	1.230	1.00
152_D	178_H	1.226	1.00
392_R	399_M	1.226	1.00
455_F	459_V	1.220	1.00
368_I	374_G	1.204	1.00
296_I	299_A	1.203	1.00
141_G	170_G	1.196	1.00
443_V	447_I	1.194	1.00
309_I	368_I	1.191	1.00
28_I	122_G	1.188	1.00
398_Y	412_A	1.188	1.00
342_A	419_G	1.185	1.00
200_A	232_C	1.185	1.00
28_I	126_C	1.184	1.00
114_A	118_L	1.178	1.00
85_L	120_S	1.171	1.00
59_F	63_G	1.169	1.00
32_G	118_L	1.163	1.00
149_V	176_V	1.161	1.00
201_K	230_T	1.160	1.00
447_I	451_F	1.156	1.00
30_F	56_L	1.143	1.00
303_S	350_T	1.140	1.00
299_A	302_L	1.139	1.00
383_H	398_Y	1.136	1.00
428_E	432_E	1.123	1.00
402_H	419_G	1.123	1.00
331_K	334_E	1.117	1.00
319_G	402_H	1.116	1.00
384_A	391_Y	1.116	1.00
457_G	460_N	1.107	1.00
387_H	427_M	1.102	1.00
197_V	226_Q	1.099	1.00
421_T	426_K	1.097	1.00
378_V	450_V	1.095	1.00
386_A	390_Q	1.085	1.00
277_E	447_I	1.083	1.00
384_A	388_N	1.080	1.00
338_V	384_A	1.077	1.00
383_H	412_A	1.068	1.00
292_V	296_I	1.067	1.00
355_F	361_L	1.065	0.99
421_T	430_R	1.062	0.99
81_F	124_V	1.059	0.99
360_S	441_W	1.059	0.99
295_C	298_L	1.059	0.99
92_V	116_Y	1.058	0.99
341_Q	383_H	1.054	0.99
398_Y	430_R	1.054	0.99
296_I	300_V	1.051	0.99
335_N	339_V	1.049	0.99
335_N	338_V	1.047	0.99
148_A	175_G	1.043	0.99
119_T	123_L	1.042	0.99
28_I	32_G	1.038	0.99
110_K	114_A	1.033	0.99
337_K	412_A	1.032	0.99
174_V	205_I	1.032	0.99
277_E	450_V	1.029	0.99
416_G	421_T	1.025	0.99
88_W	120_S	1.023	0.99
279_I	371_L	1.019	0.99
377_I	408_I	1.017	0.99
287_L	290_S	1.012	0.99
279_I	367_F	1.012	0.99
310_F	384_A	1.011	0.99
426_K	430_R	1.010	0.99
208_V	227_L	1.006	0.99
398_Y	402_H	1.006	0.99
383_H	401_R	1.006	0.99
292_V	364_L	1.005	0.99
152_D	156_G	1.005	0.99
273_L	277_E	1.002	0.99
341_Q	391_Y	0.994	0.99
160_M	173_V	0.990	0.99
400_L	439_R	0.988	0.99
200_A	227_L	0.985	0.99
272_L	276_A	0.982	0.99
341_Q	427_M	0.977	0.99
300_V	304_S	0.973	0.99
383_H	386_A	0.971	0.99
411_W	433_F	0.970	0.99
338_V	386_A	0.970	0.99
383_H	431_V	0.964	0.99
276_A	279_I	0.963	0.99
419_G	427_M	0.962	0.99
199_D	205_I	0.962	0.99
339_V	386_A	0.961	0.99
383_H	419_G	0.958	0.99
216_D	219_R	0.957	0.99
160_M	187_N	0.957	0.99
63_G	87_N	0.954	0.99
138_R	143_N	0.949	0.99
418_R	441_W	0.949	0.99
421_T	433_F	0.946	0.99
342_A	383_H	0.943	0.99
303_S	352_V	0.940	0.99
342_A	421_T	0.937	0.99
411_W	445_F	0.935	0.99
313_T	386_A	0.932	0.99
26_I	56_L	0.932	0.99
62_L	66_T	0.931	0.99
293_L	364_L	0.931	0.99
289_I	367_F	0.930	0.99
312_Q	384_A	0.925	0.99
301_K	305_P	0.923	0.99
24_S	28_I	0.922	0.99
369_N	374_G	0.920	0.99
25_D	127_R	0.919	0.99
301_K	304_S	0.916	0.98
455_F	461_K	0.914	0.98
386_A	391_Y	0.914	0.98
450_V	457_G	0.914	0.98
342_A	427_M	0.914	0.98
281_L	450_V	0.913	0.98
399_M	402_H	0.911	0.98
82_A	86_Q	0.906	0.98
190_A	199_D	0.901	0.98
37_C	41_G	0.901	0.98
274_K	278_D	0.901	0.98
36_V	114_A	0.901	0.98
300_V	352_V	0.900	0.98
398_Y	427_M	0.898	0.98
343_T	412_A	0.897	0.98
387_H	419_G	0.896	0.98
293_L	368_I	0.894	0.98
398_Y	419_G	0.894	0.98
277_E	377_I	0.891	0.98
149_V	211_A	0.891	0.98
412_A	430_R	0.889	0.98
387_H	433_F	0.889	0.98
421_T	427_M	0.889	0.98
384_A	430_R	0.887	0.98
73_R	138_R	0.886	0.98
148_A	205_I	0.885	0.98
167_P	170_G	0.885	0.98
191_G	195_Q	0.884	0.98
88_W	119_T	0.881	0.98
35_L	39_V	0.879	0.98
420_E	461_K	0.876	0.98
341_Q	384_A	0.875	0.98
315_Y	384_A	0.875	0.98
59_F	91_S	0.869	0.98
415_N	433_F	0.863	0.98
321_P	385_V	0.856	0.98
427_M	431_V	0.855	0.98
322_I	375_M	0.855	0.98
342_A	347_P	0.855	0.98
179_D	219_R	0.853	0.98
77_A	128_S	0.853	0.98
298_L	301_K	0.851	0.98
416_G	441_W	0.850	0.98
56_L	60_Q	0.848	0.97
385_V	388_N	0.845	0.97
388_N	391_Y	0.843	0.97
341_Q	420_E	0.841	0.97
274_K	376_S	0.839	0.97
151_G	211_A	0.836	0.97
110_K	113_L	0.835	0.97
221_K	225_H	0.834	0.97
398_Y	431_V	0.831	0.97
387_H	412_A	0.828	0.97
185_V	188_D	0.824	0.97
200_A	208_V	0.824	0.97
330_M	342_A	0.824	0.97
123_L	126_C	0.824	0.97
418_R	430_R	0.823	0.97
451_F	455_F	0.823	0.97
299_A	303_S	0.822	0.97
426_K	429_K	0.819	0.97
175_G	190_A	0.818	0.97
79_T	82_A	0.817	0.97
351_K	354_N	0.816	0.97
280_V	284_L	0.812	0.97
315_Y	387_H	0.811	0.97
309_I	323_K	0.810	0.97
146_M	204_K	0.809	0.97
50_L	53_L	0.808	0.97
340_T	347_P	0.805	0.97
412_A	427_M	0.805	0.97
388_N	402_H	0.805	0.97
401_R	430_R	0.801	0.96
62_L	87_N	0.799	0.96
338_V	387_H	0.798	0.96
100_A	108_Q	0.797	0.96
152_D	179_D	0.796	0.96
360_S	416_G	0.796	0.96
360_S	430_R	0.794	0.96
387_H	402_H	0.792	0.96
35_L	38_E	0.792	0.96
58_V	91_S	0.791	0.96
415_N	452_L	0.788	0.96
333_M	338_V	0.786	0.96
37_C	40_S	0.784	0.96
134_A	143_N	0.779	0.96
391_Y	401_R	0.779	0.96
126_C	130_I	0.777	0.96
315_Y	385_V	0.776	0.96
277_E	280_V	0.776	0.96
339_V	387_H	0.775	0.96
352_V	355_F	0.775	0.96
123_L	127_R	0.772	0.96
146_M	174_V	0.771	0.96
28_I	123_L	0.770	0.96
415_N	419_G	0.769	0.96
294_C	297_A	0.768	0.95
134_A	138_R	0.768	0.95
73_R	143_N	0.764	0.95
48_H	52_A	0.763	0.95
270_N	441_W	0.761	0.95
133_G	137_L	0.760	0.95
384_A	398_Y	0.758	0.95
335_N	384_A	0.755	0.95
338_V	342_A	0.754	0.95
338_V	383_H	0.753	0.95
148_A	199_D	0.752	0.95
401_R	427_M	0.752	0.95
337_K	387_H	0.751	0.95
411_W	419_G	0.749	0.95
227_L	234_V	0.747	0.95
66_T	87_N	0.746	0.95
154_A	292_V	0.746	0.95
77_A	81_F	0.741	0.95
383_H	402_H	0.740	0.95
100_A	103_N	0.739	0.94
338_V	412_A	0.738	0.94
304_S	352_V	0.738	0.94
338_V	391_Y	0.738	0.94
80_E	127_R	0.737	0.94
83_L	86_Q	0.733	0.94
341_Q	385_V	0.732	0.94
291_P	295_C	0.731	0.94
117_A	121_I	0.730	0.94
384_A	421_T	0.730	0.94
444_W	447_I	0.730	0.94
100_A	110_K	0.728	0.94
340_T	343_T	0.728	0.94
281_L	367_F	0.728	0.94
222_K	226_Q	0.727	0.94
338_V	427_M	0.723	0.94
197_V	200_A	0.723	0.94
96_A	100_A	0.722	0.94
147_V	209_Y	0.722	0.94
341_Q	412_A	0.721	0.94
186_S	189_W	0.721	0.94
93_I	97_G	0.721	0.94
333_M	347_P	0.721	0.94
335_N	341_Q	0.720	0.94
337_K	384_A	0.720	0.94
196_L	200_A	0.720	0.94
331_K	349_V	0.720	0.94
384_A	419_G	0.719	0.94
156_G	211_A	0.717	0.94
343_T	383_H	0.716	0.93
315_Y	383_H	0.715	0.93
410_G	430_R	0.714	0.93
122_G	126_C	0.712	0.93
198_E	201_K	0.712	0.93
322_I	388_N	0.711	0.93
180_P	184_G	0.711	0.93
121_I	124_V	0.711	0.93
89_T	93_I	0.710	0.93
306_G	332_V	0.709	0.93
293_L	367_F	0.707	0.93
138_R	170_G	0.706	0.93
157_Q	161_E	0.706	0.93
384_A	412_A	0.703	0.93
412_A	462_A	0.703	0.93
159_L	209_Y	0.703	0.93
341_Q	419_G	0.702	0.93
387_H	421_T	0.702	0.93
402_H	412_A	0.702	0.93
285_I	450_V	0.701	0.93
312_Q	324_V	0.701	0.93
289_I	296_I	0.700	0.93
273_L	276_A	0.700	0.93
179_D	191_G	0.699	0.93
219_R	222_K	0.698	0.93
410_G	431_V	0.698	0.93
173_V	187_N	0.697	0.93
312_Q	401_R	0.696	0.93
456_K	459_V	0.696	0.93
391_Y	431_V	0.696	0.93
67_D	70_R	0.693	0.92
334_E	342_A	0.693	0.92
120_S	124_V	0.693	0.92
48_H	108_Q	0.693	0.92
158_M	162_S	0.692	0.92
86_Q	90_L	0.691	0.92
342_A	384_A	0.690	0.92
40_S	100_A	0.689	0.92
29_M	123_L	0.689	0.92
196_L	259_V	0.689	0.92
137_L	142_Y	0.689	0.92
48_H	109_L	0.686	0.92
412_A	421_T	0.684	0.92
48_H	107_T	0.684	0.92
400_L	403_K	0.681	0.92
325_W	374_G	0.680	0.92
337_K	342_A	0.678	0.92
39_V	118_L	0.678	0.92
324_V	329_S	0.677	0.91
388_N	401_R	0.676	0.91
330_M	349_V	0.675	0.91
334_E	338_V	0.674	0.91
87_N	91_S	0.673	0.91
360_S	456_K	0.671	0.91
176_V	189_W	0.671	0.91
300_V	308_V	0.670	0.91
35_L	118_L	0.670	0.91
457_G	462_A	0.670	0.91
338_V	341_Q	0.670	0.91
228_A	262_Y	0.669	0.91
22_R	64_G	0.669	0.91
89_T	120_S	0.666	0.91
300_V	361_L	0.666	0.91
412_A	433_F	0.666	0.91
342_A	398_Y	0.662	0.91
145_R	207_N	0.662	0.91
311_R	324_V	0.661	0.90
343_T	419_G	0.661	0.90
152_D	189_W	0.660	0.90
411_W	449_I	0.658	0.90
402_H	430_R	0.654	0.90
143_N	170_G	0.653	0.90
334_E	340_T	0.652	0.90
148_A	190_A	0.651	0.90
302_L	305_P	0.650	0.90
156_G	178_H	0.648	0.90
334_E	341_Q	0.647	0.90
429_K	433_F	0.647	0.90
301_K	307_P	0.647	0.90
191_G	199_D	0.646	0.89
312_Q	335_N	0.645	0.89
282_A	377_I	0.645	0.89
153_L	180_P	0.645	0.89
387_H	398_Y	0.644	0.89
257_P	439_R	0.644	0.89
35_L	122_G	0.643	0.89
436_E	445_F	0.641	0.89
156_G	179_D	0.641	0.89
324_V	388_N	0.641	0.89
370_V	450_V	0.640	0.89
276_A	280_V	0.633	0.88
342_A	462_A	0.632	0.88
299_A	355_F	0.630	0.88
30_F	34_W	0.627	0.88
401_R	412_A	0.627	0.88
180_P	219_R	0.626	0.88
286_L	293_L	0.625	0.88
400_L	435_L	0.624	0.88
159_L	163_F	0.623	0.88
388_N	427_M	0.621	0.88
119_T	122_G	0.620	0.87
296_I	352_V	0.619	0.87
315_Y	322_I	0.618	0.87
456_K	460_N	0.617	0.87
34_W	38_E	0.615	0.87
339_V	384_A	0.614	0.87
378_V	414_I	0.610	0.87
346_D	349_V	0.609	0.87
209_Y	258_V	0.606	0.86
412_A	415_N	0.606	0.86
130_I	133_G	0.605	0.86
293_L	296_I	0.605	0.86
390_Q	393_Q	0.605	0.86
291_P	367_F	0.602	0.86
284_L	288_L	0.602	0.86
391_Y	402_H	0.601	0.86
113_L	117_A	0.600	0.86
303_S	356_L	0.600	0.86
197_V	201_K	0.600	0.86
342_A	388_N	0.598	0.86
213_Q	216_D	0.597	0.85
32_G	40_S	0.596	0.85
235_L	260_P	0.595	0.85
40_S	103_N	0.595	0.85
350_T	354_N	0.593	0.85
282_A	287_L	0.593	0.85
288_L	291_P	0.593	0.85
418_R	427_M	0.592	0.85
293_L	297_A	0.589	0.85
178_H	219_R	0.589	0.85
147_V	207_N	0.588	0.85
52_A	56_L	0.587	0.84
84_L	123_L	0.587	0.84
388_N	420_E	0.587	0.84
162_S	255_G	0.586	0.84
313_T	385_V	0.584	0.84
295_C	303_S	0.584	0.84
360_S	427_M	0.584	0.84
418_R	421_T	0.584	0.84
391_Y	421_T	0.583	0.84
325_W	368_I	0.583	0.84
95_S	99_V	0.583	0.84
312_Q	383_H	0.582	0.84
134_A	141_G	0.582	0.84
305_P	331_K	0.579	0.84
402_H	421_T	0.578	0.84
39_V	112_W	0.578	0.84
108_Q	112_W	0.577	0.83
193_L	197_V	0.575	0.83
402_H	427_M	0.574	0.83
280_V	283_T	0.574	0.83
218_A	222_K	0.573	0.83
338_V	398_Y	0.573	0.83
410_G	413_Q	0.572	0.83
289_I	327_F	0.572	0.83
322_I	325_W	0.571	0.83
442_S	445_F	0.571	0.83
210_I	220_V	0.570	0.83
344_Q	347_P	0.570	0.83
342_A	420_E	0.569	0.83
388_N	426_K	0.568	0.83
103_N	107_T	0.567	0.82
293_L	300_V	0.566	0.82
101_F	113_L	0.566	0.82
26_I	30_F	0.565	0.82
427_M	433_F	0.564	0.82
171_F	207_N	0.563	0.82
292_V	295_C	0.563	0.82
36_V	122_G	0.563	0.82
334_E	384_A	0.562	0.82
341_Q	421_T	0.561	0.82
419_G	433_F	0.561	0.82
334_E	347_P	0.560	0.82
92_V	288_L	0.560	0.82
430_R	441_W	0.560	0.82
101_F	183_G	0.559	0.82
125_V	198_E	0.557	0.81
297_A	300_V	0.556	0.81
383_H	421_T	0.556	0.81
312_Q	427_M	0.554	0.81
383_H	411_W	0.554	0.81
388_N	430_R	0.553	0.81
179_D	193_L	0.553	0.81
420_E	427_M	0.553	0.81
450_V	454_V	0.552	0.81
342_A	401_R	0.551	0.81
310_F	385_V	0.551	0.81
274_K	441_W	0.551	0.81
386_A	427_M	0.550	0.80
209_Y	301_K	0.550	0.80
60_Q	69_Y	0.550	0.80
200_A	205_I	0.548	0.80
275_R	405_K	0.545	0.80
335_N	342_A	0.544	0.80
116_Y	119_T	0.543	0.80
315_Y	420_E	0.542	0.80
304_S	350_T	0.540	0.79
227_L	231_T	0.540	0.79
233_S	260_P	0.540	0.79
343_T	384_A	0.539	0.79
323_K	374_G	0.539	0.79
34_W	37_C	0.539	0.79
435_L	439_R	0.539	0.79
380_P	430_R	0.539	0.79
97_G	101_F	0.539	0.79
341_Q	388_N	0.536	0.79
301_K	332_V	0.534	0.79
317_M	405_K	0.534	0.79
32_G	35_L	0.534	0.79
31_A	35_L	0.534	0.79
176_V	187_N	0.532	0.78
360_S	457_G	0.532	0.78
207_N	233_S	0.532	0.78
344_Q	420_E	0.532	0.78
301_K	309_I	0.532	0.78
236_L	261_L	0.531	0.78
128_S	132_I	0.531	0.78
367_F	456_K	0.531	0.78
387_H	390_Q	0.530	0.78
334_E	339_V	0.529	0.78
343_T	420_E	0.529	0.78
63_G	123_L	0.529	0.78
73_R	141_G	0.528	0.78
127_R	131_R	0.528	0.78
100_A	107_T	0.528	0.78
383_H	406_P	0.527	0.78
456_K	462_A	0.527	0.78
152_D	176_V	0.527	0.78
341_Q	392_R	0.526	0.77
387_H	401_R	0.526	0.77
275_R	278_D	0.525	0.77
45_L	121_I	0.525	0.77
65_I	405_K	0.524	0.77
279_I	286_L	0.522	0.77
401_R	410_G	0.522	0.77
324_V	383_H	0.521	0.77
281_L	284_L	0.521	0.77
286_L	371_L	0.521	0.77
384_A	402_H	0.520	0.77
46_Y	161_E	0.519	0.77
179_D	192_N	0.519	0.77
386_A	431_V	0.518	0.76
385_V	401_R	0.518	0.76
383_H	426_K	0.517	0.76
337_K	419_G	0.515	0.76
157_Q	185_V	0.514	0.76
36_V	111_I	0.514	0.76
303_S	329_S	0.512	0.76
351_K	355_F	0.511	0.75
318_D	403_K	0.511	0.75
109_L	113_L	0.511	0.75
302_L	351_K	0.511	0.75
129_C	133_G	0.511	0.75
62_L	65_I	0.510	0.75
251_E	260_P	0.507	0.75
306_G	350_T	0.507	0.75
403_K	439_R	0.507	0.75
310_F	387_H	0.506	0.75
383_H	390_Q	0.505	0.75
221_K	234_V	0.504	0.74
344_Q	391_Y	0.504	0.74
385_V	427_M	0.504	0.74
88_W	123_L	0.504	0.74
308_V	327_F	0.503	0.74
309_I	374_G	0.503	0.74
40_S	108_Q	0.503	0.74
33_L	52_A	0.503	0.74
25_D	32_G	0.503	0.74
121_I	125_V	0.502	0.74
398_Y	421_T	0.502	0.74
312_Q	373_G	0.501	0.74
29_M	59_F	0.500	0.74

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3nklA	2	0.2392	99.2	0.905	Contact Map
3keoA	2	0.4246	98	0.934	Contact Map
3wg9A	2	0.4353	97.8	0.938	Contact Map
2dt5A	3	0.4289	97.6	0.94	Contact Map
2vt3A	2	0.431	97.5	0.942	Contact Map
2py6A	4	0.6185	97.3	0.944	Contact Map
4m98A	3	0.4397	96.8	0.948	Contact Map
4rv9A	1	0.5237	95.3	0.954	Contact Map
4ea9A	3	0.4159	92.6	0.959	Contact Map
3ff4A	1	0.2414	89.9	0.962	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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