GREMLIN Database
HYFR - Hydrogenase-4 transcriptional activator
UniProt: P71229 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14219
Length: 670 (511)
Sequences: 392 (322)
Seq/√Len: 14.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
232_T269_L5.9281.00
494_M499_Q4.5821.00
330_E334_L4.4271.00
327_L330_E4.2861.00
357_L513_L4.1501.00
490_D493_Q4.0691.00
639_A646_T3.7971.00
436_E470_R3.7050.99
434_R469_E3.4230.99
450_D494_M3.3970.99
331_N334_L3.2570.99
489_R494_M3.2420.98
247_L251_Q3.1180.98
309_I313_N3.1040.98
420_D430_T3.0310.98
368_D539_H3.0180.98
327_L334_L2.9930.97
533_T547_I2.9750.97
485_A508_L2.9190.97
493_Q497_D2.7830.96
354_M358_L2.7680.96
248_F251_Q2.7340.96
654_T657_S2.6560.95
653_T657_S2.5530.93
174_I192_M2.5500.93
413_E458_K2.5250.93
450_D485_A2.5090.93
535_K568_E2.4660.92
354_M564_V2.4600.92
529_A547_I2.4570.92
651_K654_T2.4550.92
419_H431_H2.4260.92
334_L337_Q2.3940.91
299_L636_G2.3310.90
450_D488_N2.2300.88
443_L483_V2.2200.87
407_I457_P2.1970.87
382_E461_R2.1940.87
450_D512_P2.1820.86
349_Y431_H2.1320.85
379_T515_L2.0970.84
395_R513_L2.0660.83
420_D477_I2.0440.82
374_C643_G2.0140.81
434_R470_R1.9780.80
225_E230_T1.9490.79
434_R476_T1.9300.79
515_L576_L1.9180.78
373_I539_H1.9130.78
627_I659_M1.9060.78
632_R636_G1.9020.78
319_S322_D1.8990.77
327_L331_N1.8800.77
405_A413_E1.8600.76
638_V654_T1.8550.76
420_D470_R1.8470.75
635_N652_R1.8320.75
576_L658_R1.8210.74
412_L451_L1.8130.74
409_A454_E1.8020.73
455_L575_V1.7830.73
367_S576_L1.7820.73
361_V384_I1.7820.73
269_L283_L1.7750.72
327_L357_L1.7750.72
320_M323_L1.7750.72
420_D473_G1.7650.72
269_L281_A1.7560.71
394_R480_N1.7440.71
583_L651_K1.7290.70
384_I523_E1.7240.70
470_R477_I1.7120.69
222_M225_E1.7110.69
358_L577_L1.7100.69
326_S330_E1.7080.69
637_I646_T1.7040.69
401_K469_E1.7030.69
622_E626_R1.6960.69
399_L441_G1.6770.68
434_R451_L1.6600.67
374_C492_W1.6490.66
412_L636_G1.6440.66
457_P636_G1.6210.65
226_S230_T1.6160.65
538_R624_R1.6150.65
376_E519_R1.6100.65
373_I384_I1.6010.64
619_N622_E1.5920.64
638_V643_G1.5850.63
632_R635_N1.5820.63
299_L307_I1.5800.63
330_E333_Q1.5800.63
379_T509_N1.5790.63
414_S424_F1.5710.63
421_K664_I1.5650.62
511_F638_V1.5480.61
441_G531_H1.5430.61
406_A416_L1.5390.61
440_G480_N1.5290.60
274_F279_P1.5280.60
227_V251_Q1.5160.60
511_F659_M1.5010.59
434_R569_N1.4970.59
324_Q327_L1.4940.59
651_K657_S1.4910.58
448_I574_A1.4910.58
621_E650_M1.4900.58
158_V306_R1.4820.58
306_R466_R1.4780.58
306_R638_V1.4730.57
452_P455_L1.4710.57
401_K467_E1.4700.57
334_L485_A1.4580.57
303_I307_I1.4460.56
174_I270_I1.4390.56
407_I470_R1.4260.55
652_R656_L1.4250.55
395_R493_Q1.4210.55
274_F533_T1.4210.55
434_R568_E1.4150.54
634_T647_R1.4110.54
448_I660_Q1.4050.54
431_H658_R1.3990.53
637_I654_T1.3950.53
654_T658_R1.3790.52
152_D365_A1.3760.52
331_N335_S1.3750.52
634_T644_A1.3750.52
244_A267_A1.3740.52
596_P599_N1.3650.52
423_A505_F1.3640.52
502_S576_L1.3620.51
436_E469_E1.3600.51
299_L348_I1.3590.51
348_I527_L1.3580.51
174_I450_D1.3540.51
407_I494_M1.3500.51
357_L402_I1.3440.50
166_S579_R1.3430.50
547_I571_I1.3380.50
637_I643_G1.3280.50
299_L303_I1.3200.49
346_D354_M1.3150.49
643_G654_T1.3110.49
407_I492_W1.3090.48
347_I512_P1.3070.48
421_K442_T1.3000.48
346_D390_Q1.3000.48
327_L485_A1.2990.48
467_E476_T1.2950.48
488_N494_M1.2830.47
229_L241_T1.2820.47
168_L192_M1.2790.47
399_L513_L1.2760.47
436_E477_I1.2730.47
625_Q664_I1.2700.46
445_L645_A1.2610.46
450_D466_R1.2610.46
572_E658_R1.2610.46
483_V571_I1.2540.45
576_L636_G1.2530.45
435_F462_V1.2510.45
347_I434_R1.2480.45
467_E478_P1.2420.45
529_A548_P1.2310.44
361_V365_A1.2300.44
469_E476_T1.2210.44
298_Q564_V1.2200.44
268_L586_H1.2190.44
281_A411_L1.2180.44
230_T251_Q1.2110.43
553_R664_I1.2110.43
468_I483_V1.2060.43
354_M632_R1.2000.43
222_M230_T1.1980.42
253_D257_L1.1980.42
379_T542_R1.1950.42
479_V645_A1.1910.42
407_I468_I1.1900.42
397_K440_G1.1840.42
511_F576_L1.1820.42
631_L658_R1.1810.42
490_D552_L1.1790.41
277_H421_K1.1730.41
275_G484_I1.1630.41
276_N410_S1.1610.41
448_I556_M1.1560.40
638_V657_S1.1450.40
402_I619_N1.1450.40
286_H296_N1.1410.39
600_E605_R1.1390.39
413_E623_E1.1390.39
448_I483_V1.1380.39
475_R483_V1.1350.39
451_L506_Y1.1330.39
517_P597_T1.1330.39
194_L298_Q1.1320.39
345_G361_V1.1320.39
506_Y623_E1.1310.39
443_L508_L1.1300.39
170_L305_D1.1290.39
510_V573_R1.1270.39
155_R520_D1.1250.39
468_I478_P1.1220.38
322_D396_D1.1190.38
373_I443_L1.1140.38
295_E339_L1.1100.38
222_M227_V1.1100.38
548_P585_L1.1000.37
348_I647_R1.0990.37
428_I476_T1.0970.37
412_L638_V1.0930.37
402_I555_L1.0920.37
187_L190_V1.0920.37
526_P529_A1.0910.37
532_F571_I1.0870.37
457_P470_R1.0830.36
285_A654_T1.0770.36
628_V664_I1.0740.36
646_T654_T1.0720.36
407_I434_R1.0710.36
434_R636_G1.0690.36
272_L308_A1.0680.36
574_A634_T1.0660.36
351_S458_K1.0640.36
230_T267_A1.0610.35
243_R247_L1.0560.35
333_Q371_V1.0510.35
358_L583_L1.0510.35
299_L477_I1.0490.35
351_S413_E1.0480.35
334_L508_L1.0470.35
192_M303_I1.0450.35
272_L400_V1.0440.35
600_E603_A1.0430.34
316_A323_L1.0370.34
544_I635_N1.0360.34
305_D636_G1.0320.34
239_T533_T1.0310.34
227_V230_T1.0300.34
203_F235_T1.0250.34
401_K420_D1.0250.34
220_R232_T1.0220.33
358_L361_V1.0180.33
319_S323_L1.0170.33
435_F566_E1.0160.33
547_I557_S1.0150.33
542_R577_L1.0110.33
177_V307_I1.0100.33
356_D581_N1.0100.33
523_E526_P1.0080.33
292_F662_L1.0020.32
414_S532_F1.0020.32
626_R666_V1.0010.32
225_E251_Q0.9980.32
374_C452_P0.9980.32
475_R496_E0.9930.32
179_R496_E0.9920.32
401_K436_E0.9890.32
220_R226_S0.9860.32
419_H424_F0.9820.32
181_I638_V0.9780.31
154_H630_V0.9700.31
358_L564_V0.9700.31
643_G657_S0.9670.31
180_E373_I0.9650.31
361_V624_R0.9620.31
324_Q535_K0.9610.31
455_L653_T0.9610.31
630_V635_N0.9600.30
397_K527_L0.9600.30
647_R652_R0.9590.30
402_I457_P0.9550.30
354_M582_S0.9530.30
431_H639_A0.9520.30
354_M384_I0.9500.30
443_L450_D0.9470.30
457_P544_I0.9470.30
522_P588_N0.9470.30
471_L634_T0.9450.30
284_L539_H0.9420.30
492_W664_I0.9410.30
307_I473_G0.9330.29
443_L462_V0.9320.29
214_H219_P0.9310.29
303_I636_G0.9310.29
408_P471_L0.9310.29
405_A458_K0.9280.29
365_A494_M0.9260.29
164_V570_V0.9240.29
235_T297_C0.9240.29
303_I476_T0.9240.29
508_L631_L0.9220.29
653_T656_L0.9220.29
204_S615_T0.9210.29
255_L384_I0.9210.29
196_D479_V0.9150.28
399_L409_A0.9130.28
451_L455_L0.9120.28
511_F654_T0.9060.28
383_V410_S0.9060.28
373_I505_F0.9060.28
387_A401_K0.9050.28
405_A461_R0.9030.28
377_T432_R0.9020.28
466_R636_G0.9010.28
536_M539_H0.8970.28
281_A476_T0.8940.28
502_S532_F0.8930.27
170_L174_I0.8930.27
243_R251_Q0.8890.27
408_P667_R0.8870.27
583_L643_G0.8860.27
468_I515_L0.8850.27
301_Q484_I0.8830.27
526_P552_L0.8830.27
310_A387_A0.8830.27
284_L311_V0.8820.27
400_V453_L0.8810.27
226_S251_Q0.8810.27
359_Q362_D0.8770.27
412_L637_I0.8770.27
172_D179_R0.8750.27
316_A320_M0.8720.27
300_L527_L0.8720.27
391_L502_S0.8710.27
618_E626_R0.8710.27
331_N511_F0.8710.27
467_E568_E0.8710.27
297_C625_Q0.8700.26
185_F511_F0.8690.26
508_L658_R0.8670.26
462_V468_I0.8650.26
379_T465_E0.8650.26
356_D360_Q0.8580.26
270_I296_N0.8580.26
589_V658_R0.8560.26
615_T622_E0.8560.26
276_N649_G0.8560.26
192_M395_R0.8530.26
246_D251_Q0.8520.26
179_R384_I0.8520.26
643_G646_T0.8500.26
643_G651_K0.8460.25
155_R219_P0.8460.25
226_S232_T0.8440.25
315_D354_M0.8420.25
428_I541_N0.8390.25
359_Q468_I0.8360.25
299_L412_L0.8350.25
269_L529_A0.8330.25
170_L311_V0.8320.25
493_Q543_A0.8300.25
296_N406_A0.8290.25
450_D525_I0.8290.25
575_V666_V0.8280.25
361_V597_T0.8230.25
384_I564_V0.8220.24
434_R494_M0.8220.24
369_S469_E0.8220.24
189_S210_L0.8210.24
229_L551_A0.8160.24
358_L384_I0.8150.24
193_V361_V0.8140.24
312_G564_V0.8110.24
387_A436_E0.8110.24
231_Q239_T0.8090.24
605_R610_Q0.8090.24
522_P525_I0.8040.24
197_H443_L0.8030.24
604_L609_A0.8030.24
605_R611_L0.8020.24
485_A512_P0.8020.24
347_I387_A0.7990.24
367_S498_R0.7990.24
483_V612_L0.7970.23
355_E513_L0.7940.23
467_E492_W0.7940.23
152_D499_Q0.7920.23
158_V161_T0.7910.23
420_D434_R0.7900.23
449_G487_T0.7900.23
327_L370_T0.7900.23
307_I536_M0.7880.23
347_I368_D0.7870.23
511_F540_M0.7870.23
232_T247_L0.7830.23
164_V534_Q0.7820.23
388_I525_I0.7820.23
236_R443_L0.7810.23
633_E647_R0.7810.23
508_L576_L0.7800.23
424_F532_F0.7800.23
311_V419_H0.7790.23
407_I632_R0.7770.23
348_I620_D0.7750.23
161_T309_I0.7710.22
388_I649_G0.7680.22
542_R626_R0.7670.22
337_Q348_I0.7630.22
153_H299_L0.7630.22
407_I479_V0.7600.22
450_D489_R0.7600.22
364_V510_V0.7590.22
498_R552_L0.7570.22
172_D321_T0.7570.22
467_E566_E0.7560.22
230_T284_L0.7560.22
204_S408_P0.7560.22
374_C421_K0.7540.22
405_A437_I0.7540.22
368_D373_I0.7530.22
431_H489_R0.7530.22
423_A471_L0.7520.22
405_A505_F0.7520.22
244_A250_W0.7520.22
265_E537_A0.7510.22
318_R321_T0.7500.22
407_I531_H0.7490.22
317_W323_L0.7480.22
347_I361_V0.7480.22
188_A377_T0.7470.22
480_N624_R0.7470.22
376_E517_P0.7460.22
243_R249_L0.7460.22
175_A564_V0.7450.22
536_M575_V0.7430.21
347_I517_P0.7400.21
404_C445_L0.7390.21
434_R639_A0.7390.21
651_K656_L0.7390.21
264_C423_A0.7390.21
534_Q568_E0.7370.21
410_S498_R0.7370.21
547_I631_L0.7370.21
190_V468_I0.7340.21
474_S499_Q0.7330.21
342_L531_H0.7320.21
637_I661_R0.7310.21
160_I250_W0.7300.21
354_M441_G0.7290.21
174_I305_D0.7280.21
185_F661_R0.7240.21
437_I469_E0.7230.21
179_R538_R0.7220.21
529_A660_Q0.7220.21
258_L423_A0.7210.21
360_Q587_L0.7210.21
467_E471_L0.7170.20
289_S513_L0.7160.20
457_P637_I0.7160.20
465_E496_E0.7160.20
470_R657_S0.7160.20
630_V644_A0.7150.20
413_E505_F0.7140.20
651_K658_R0.7140.20
407_I656_L0.7140.20
526_P635_N0.7130.20
436_E473_G0.7120.20
309_I369_S0.7110.20
296_N351_S0.7100.20
615_T626_R0.7100.20
334_L483_V0.7100.20
473_G535_K0.7100.20
277_H296_N0.7060.20
576_L631_L0.7050.20
543_A611_L0.7040.20
303_I329_Q0.7040.20
512_P573_R0.7040.20
185_F286_H0.7020.20
172_D480_N0.7010.20
496_E625_Q0.7010.20
235_T407_I0.6970.20
242_H307_I0.6970.20
296_N484_I0.6950.20
320_M508_L0.6950.20
627_I655_L0.6950.20
318_R322_D0.6940.20
356_D520_D0.6940.20
569_N651_K0.6940.20
293_S484_I0.6930.20
413_E455_L0.6930.20
327_L333_Q0.6920.20
637_I657_S0.6920.20
431_H578_T0.6920.20
233_L431_H0.6910.20
431_H495_V0.6910.20
419_H568_E0.6910.20
161_T166_S0.6900.20
560_W572_E0.6890.20
217_C348_I0.6880.19
387_A470_R0.6880.19
520_D529_A0.6880.19
407_I450_D0.6870.19
574_A656_L0.6860.19
609_A612_L0.6860.19
157_L623_E0.6830.19
220_R225_E0.6820.19
233_L241_T0.6820.19
347_I467_E0.6820.19
532_F661_R0.6800.19
226_S250_W0.6790.19
576_L619_N0.6790.19
304_A388_I0.6790.19
434_R468_I0.6790.19
435_F488_N0.6780.19
388_I439_D0.6780.19
410_S483_V0.6770.19
542_R575_V0.6770.19
214_H220_R0.6760.19
544_I571_I0.6760.19
177_V477_I0.6760.19
181_I443_L0.6750.19
184_F410_S0.6750.19
622_E650_M0.6740.19
558_W658_R0.6730.19
552_L622_E0.6710.19
421_K650_M0.6700.19
171_D471_L0.6690.19
169_D400_V0.6680.19
547_I660_Q0.6670.19
626_R654_T0.6670.19
627_I662_L0.6670.19
500_F504_L0.6660.19
212_A395_R0.6640.19
470_R476_T0.6630.19
160_I474_S0.6610.19
588_N636_G0.6600.19
526_P652_R0.6590.19
226_S229_L0.6590.19
558_W576_L0.6580.18
636_G643_G0.6570.18
470_R644_A0.6560.18
412_L448_I0.6560.18
202_K450_D0.6550.18
231_Q235_T0.6550.18
416_L473_G0.6540.18
269_L530_K0.6530.18
303_I395_R0.6520.18
186_G660_Q0.6510.18
187_L377_T0.6480.18
638_V653_T0.6470.18
515_L578_T0.6470.18
595_L598_L0.6470.18
157_L413_E0.6470.18
333_Q367_S0.6430.18
181_I190_V0.6420.18
164_V191_S0.6400.18
326_S329_Q0.6380.18
572_E643_G0.6370.18
347_I383_V0.6350.18
473_G644_A0.6350.18
235_T576_L0.6320.18
488_N528_L0.6310.18
158_V434_R0.6310.18
183_H659_M0.6300.18
194_L649_G0.6280.18
470_R566_E0.6280.18
241_T247_L0.6280.18
156_V356_D0.6270.17
402_I517_P0.6250.17
236_R468_I0.6250.17
413_E488_N0.6220.17
572_E631_L0.6220.17
198_R443_L0.6210.17
185_F399_L0.6200.17
597_T609_A0.6200.17
172_D224_G0.6180.17
236_R278_T0.6180.17
272_L655_L0.6170.17
220_R230_T0.6170.17
473_G477_I0.6150.17
450_D620_D0.6140.17
370_T401_K0.6140.17
508_L558_W0.6140.17
295_E660_Q0.6120.17
342_L391_L0.6120.17
232_T505_F0.6100.17
187_L653_T0.6070.17
552_L581_N0.6070.17
173_L312_G0.6070.17
185_F189_S0.6060.17
313_N515_L0.6050.17
394_R425_T0.6050.17
434_R437_I0.6050.17
264_C383_V0.6040.17
283_L506_Y0.6040.17
170_L569_N0.6030.17
174_I409_A0.6020.17
374_C653_T0.6010.17
401_K662_L0.6010.17
466_R623_E0.6000.17
268_L454_E0.6000.17
455_L636_G0.5990.17
382_E387_A0.5990.17
502_S631_L0.5970.17
214_H248_F0.5970.17
292_F313_N0.5970.17
638_V651_K0.5970.17
224_G276_N0.5960.17
643_G653_T0.5940.16
436_E462_V0.5940.16
181_I303_I0.5930.16
361_V494_M0.5920.16
364_V512_P0.5920.16
154_H399_L0.5920.16
205_L208_S0.5920.16
639_A643_G0.5920.16
576_L622_E0.5910.16
420_D436_E0.5900.16
296_N630_V0.5900.16
242_H633_E0.5880.16
274_F400_V0.5880.16
532_F622_E0.5880.16
637_I652_R0.5880.16
197_H488_N0.5870.16
330_E602_S0.5860.16
494_M569_N0.5850.16
284_L310_A0.5850.16
350_Q588_N0.5830.16
411_L560_W0.5830.16
452_P512_P0.5820.16
278_T448_I0.5810.16
450_D457_P0.5810.16
198_R484_I0.5800.16
513_L520_D0.5790.16
400_V478_P0.5790.16
552_L609_A0.5790.16
159_D399_L0.5780.16
508_L594_L0.5780.16
576_L583_L0.5780.16
192_M267_A0.5770.16
480_N546_A0.5760.16
373_I396_D0.5750.16
161_T533_T0.5750.16
272_L557_S0.5740.16
356_D450_D0.5740.16
655_L659_M0.5730.16
169_D172_D0.5720.16
170_L314_A0.5720.16
634_T651_K0.5720.16
652_R657_S0.5710.16
185_F292_F0.5680.16
336_E454_E0.5680.16
234_Q238_P0.5680.16
372_L512_P0.5680.16
332_H348_I0.5670.16
526_P583_L0.5660.16
386_R413_E0.5660.16
412_L416_L0.5660.16
464_Q510_V0.5660.16
312_G483_V0.5650.16
164_V457_P0.5640.16
463_L483_V0.5630.16
420_D431_H0.5630.16
406_A519_R0.5630.16
353_A397_K0.5630.16
241_T267_A0.5610.15
157_L564_V0.5600.15
213_S242_H0.5600.15
240_L484_I0.5590.15
244_A398_P0.5580.15
451_L636_G0.5580.15
560_W662_L0.5570.15
452_P467_E0.5570.15
407_I541_N0.5550.15
353_A373_I0.5540.15
386_R409_A0.5540.15
315_D587_L0.5530.15
558_W561_P0.5520.15
371_V436_E0.5520.15
468_I473_G0.5510.15
643_G659_M0.5510.15
544_I575_V0.5510.15
509_N579_R0.5500.15
350_Q353_A0.5500.15
457_P498_R0.5490.15
387_A567_L0.5480.15
361_V453_L0.5470.15
164_V575_V0.5460.15
373_I522_P0.5460.15
444_F477_I0.5460.15
587_L650_M0.5450.15
407_I633_E0.5440.15
525_I605_R0.5440.15
194_L484_I0.5430.15
373_I616_T0.5430.15
480_N606_S0.5430.15
270_I301_Q0.5430.15
187_L654_T0.5410.15
168_L336_E0.5390.15
270_I400_V0.5390.15
311_V457_P0.5390.15
227_V509_N0.5390.15
439_D477_I0.5380.15
158_V570_V0.5380.15
325_E496_E0.5370.15
410_S455_L0.5360.15
267_A283_L0.5360.15
617_P649_G0.5340.15
181_I317_W0.5330.15
317_W320_M0.5330.15
309_I643_G0.5330.15
357_L440_G0.5330.15
541_N613_H0.5330.15
600_E604_L0.5330.15
540_M653_T0.5320.15
192_M229_L0.5320.15
480_N543_A0.5320.15
203_F289_S0.5310.15
474_S517_P0.5310.15
270_I300_L0.5300.15
583_L587_L0.5300.15
638_V659_M0.5300.15
282_L547_I0.5290.15
374_C379_T0.5290.15
517_P655_L0.5290.15
575_V636_G0.5280.15
451_L638_V0.5240.14
367_S578_T0.5240.14
374_C657_S0.5240.14
246_D578_T0.5240.14
272_L282_L0.5230.14
236_R300_L0.5230.14
333_Q336_E0.5220.14
244_A247_L0.5210.14
325_E334_L0.5200.14
594_L631_L0.5200.14
384_I510_V0.5190.14
469_E637_I0.5190.14
453_L554_Q0.5190.14
477_I664_I0.5190.14
195_G287_T0.5190.14
181_I483_V0.5180.14
451_L470_R0.5180.14
271_P278_T0.5180.14
598_L611_L0.5170.14
152_D319_S0.5170.14
186_G633_E0.5170.14
626_R629_Q0.5140.14
210_L305_D0.5130.14
412_L455_L0.5130.14
484_I556_M0.5130.14
170_L399_L0.5110.14
369_S579_R0.5110.14
285_A633_E0.5100.14
157_L271_P0.5090.14
227_V247_L0.5090.14
284_L540_M0.5090.14
205_L564_V0.5080.14
241_T244_A0.5080.14
466_R632_R0.5070.14
162_N471_L0.5070.14
196_D279_P0.5070.14
243_R480_N0.5070.14
550_E583_L0.5060.14
529_A552_L0.5040.14
401_K512_P0.5040.14
511_F646_T0.5040.14
451_L659_M0.5040.14
477_I608_M0.5030.14
209_D267_A0.5020.14
515_L657_S0.5020.14
405_A651_K0.5010.14
299_L305_D0.5010.14
251_Q267_A0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4l4uA 2 0.5701 100 0.51 Contact Map
3dzdA 2 0.5373 100 0.616 Contact Map
1ojlA 3 0.4493 100 0.629 Contact Map
4fwgA 3 0.5836 100 0.725 Contact Map
4qhsA 3 0.3642 100 0.782 Contact Map
4qosA 1 0.3582 100 0.784 Contact Map
1r6bX 1 0.697 100 0.795 Contact Map
1qvrA 3 0.7806 100 0.796 Contact Map
4ciuA 1 0.709 100 0.799 Contact Map
4d2uA 3 0.8134 100 0.804 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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