GREMLIN Database
FUCI - L-fucose isomerase
UniProt: P69922 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10349
Length: 591 (583)
Sequences: 277 (132)
Seq/√Len: 5.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
372_E378_K6.9331.00
360_A396_A6.0030.99
458_F480_S5.5410.99
97_I124_A5.0810.98
14_V85_T4.6160.96
379_L387_I4.6130.96
253_A257_R4.4460.95
198_E205_V4.3550.95
107_I124_A4.1270.93
516_D519_S3.9980.92
197_F344_V3.9090.91
9_I163_A3.7590.89
345_A461_T3.7050.88
59_D74_K3.3730.83
37_T84_I3.3600.83
488_H491_L3.3240.82
317_A433_W3.2870.81
180_L213_L3.2200.80
82_L166_G3.1870.79
328_V421_Q3.1750.79
199_S467_K3.0320.75
161_R539_D2.9940.74
41_L159_L2.9690.73
372_E379_L2.9210.72
532_T536_V2.8580.70
297_A334_V2.8190.69
509_T512_G2.7760.68
142_D370_A2.7500.67
377_H484_P2.7140.66
317_A448_S2.6920.66
39_A43_E2.6810.65
488_H492_N2.6740.65
270_I315_A2.6170.63
219_Q308_Q2.6080.63
224_E283_I2.5960.63
328_V424_A2.5890.62
404_Q423_E2.5840.62
129_S565_S2.5680.62
169_V546_M2.4490.58
371_I379_L2.4030.56
404_Q419_I2.3720.55
572_M577_Q2.3640.55
97_I107_I2.3370.54
489_D493_K2.3310.54
29_Q146_A2.3250.54
76_S100_D2.3080.53
566_A585_Y2.2690.52
278_S282_D2.2630.52
161_R538_A2.2110.50
214_R309_Y2.2000.49
125_L137_S2.1650.48
330_E350_H2.1470.48
425_D429_A2.1090.46
32_N35_K2.0970.46
227_L416_H2.0890.46
61_C83_T2.0770.45
419_I423_E2.0710.45
579_Y585_Y2.0660.45
227_L268_M2.0610.45
415_P418_E2.0280.44
240_Y260_L1.9900.42
433_W448_S1.9890.42
419_I427_C1.9810.42
89_C93_G1.9760.42
105_K133_I1.9700.42
234_A264_L1.9580.41
330_E569_A1.9430.41
47_H171_S1.9400.41
180_L208_V1.9140.40
21_G24_E1.9130.40
9_I41_L1.9070.40
232_A236_K1.8960.39
344_V463_V1.8940.39
231_L261_R1.8940.39
460_M529_G1.8930.39
491_L503_W1.8660.38
403_K453_E1.8620.38
125_L135_A1.8410.37
379_L505_A1.8400.37
234_A260_L1.8300.37
263_S267_A1.8220.37
412_T423_E1.8200.37
213_L309_Y1.8190.37
377_H486_D1.8010.36
96_T128_H1.7970.36
14_V124_A1.7960.36
36_A149_T1.7930.36
387_I481_V1.7920.36
6_L47_H1.7920.36
437_I496_N1.7860.36
184_S395_S1.7830.36
220_K224_E1.7690.35
407_S412_T1.7650.35
513_P572_M1.7520.35
182_G205_V1.7450.34
238_F314_T1.7430.34
387_I505_A1.7350.34
273_M292_Y1.7240.34
275_Q332_F1.7130.34
64_G184_S1.7090.33
484_P487_V1.6920.33
48_A171_S1.6860.33
137_S304_H1.6690.32
173_K507_R1.6660.32
33_M88_P1.6660.32
6_L49_C1.6640.32
8_K54_E1.6640.32
213_L448_S1.6600.32
252_N255_Q1.6550.32
19_R286_V1.6470.32
240_Y257_R1.6330.31
197_F340_S1.6240.31
157_E161_R1.6140.31
576_G580_R1.6130.31
311_N441_F1.6100.30
214_R262_E1.6100.30
382_L505_A1.6050.30
382_L455_G1.5910.30
507_R560_K1.5910.30
81_G170_A1.5750.29
488_H501_T1.5630.29
94_S99_M1.5480.29
322_S356_A1.5460.29
240_Y253_A1.5430.29
244_E434_C1.5360.28
552_C572_M1.5300.28
58_S74_K1.5110.28
479_W507_R1.4970.27
93_G190_S1.4970.27
97_I491_L1.4910.27
89_C190_S1.4790.27
41_L84_I1.4740.27
536_V540_F1.4700.27
377_H487_V1.4670.27
507_R557_E1.4450.26
38_A42_T1.4400.26
331_P484_P1.4260.25
124_A127_A1.4170.25
449_R492_N1.4160.25
35_K515_T1.4110.25
358_V400_G1.4090.25
81_G104_P1.4050.25
142_D577_Q1.4040.25
17_G21_G1.3950.25
197_F205_V1.3880.24
402_C456_V1.3800.24
65_M204_K1.3750.24
47_H354_G1.3690.24
372_E377_H1.3490.24
354_G419_I1.3440.23
396_A400_G1.3410.23
251_R438_H1.3400.23
227_L231_L1.3370.23
572_M585_Y1.3370.23
172_M351_Q1.3330.23
231_L264_L1.3290.23
218_D308_Q1.3270.23
304_H440_Y1.3270.23
388_I516_D1.3120.23
105_K349_G1.3120.23
93_G526_A1.3090.23
17_G24_E1.3060.22
510_G513_P1.3050.22
238_F260_L1.2990.22
360_A530_V1.2970.22
37_T159_L1.2840.22
61_C529_G1.2820.22
166_G170_A1.2800.22
238_F261_R1.2790.22
396_A491_L1.2790.22
358_V396_A1.2780.22
377_H380_D1.2660.22
397_A413_M1.2640.22
28_E32_N1.2640.22
45_L529_G1.2630.21
387_I439_E1.2610.21
395_S579_Y1.2570.21
81_G166_G1.2540.21
133_I565_S1.2540.21
96_T120_Y1.2500.21
170_A174_G1.2380.21
137_S292_Y1.2360.21
239_R429_A1.2290.21
321_S397_A1.2260.21
440_Y526_A1.2230.21
492_N501_T1.2190.21
235_D297_A1.2160.20
84_I159_L1.2130.20
354_G397_A1.2100.20
397_A400_G1.2060.20
254_E258_A1.1970.20
214_R308_Q1.1930.20
388_I565_S1.1930.20
14_V29_Q1.1930.20
391_I492_N1.1910.20
497_S513_P1.1880.20
397_A434_C1.1770.20
217_I309_Y1.1760.20
206_Q292_Y1.1750.20
46_R73_E1.1730.20
129_S566_A1.1710.19
292_Y451_L1.1660.19
369_E380_D1.1640.19
173_K460_M1.1620.19
355_T415_P1.1590.19
357_Q532_T1.1580.19
64_G207_A1.1560.19
219_Q285_R1.1520.19
573_D576_G1.1490.19
83_T103_R1.1430.19
244_E496_N1.1380.19
93_G440_Y1.1370.19
388_I519_S1.1360.19
255_Q259_V1.1300.19
237_N425_D1.1270.19
553_M567_W1.1250.19
434_C449_R1.1230.18
572_M576_G1.1230.18
497_S577_Q1.1170.18
178_L357_Q1.1130.18
29_Q149_T1.1120.18
238_F264_L1.1100.18
84_I179_S1.1070.18
488_H503_W1.1050.18
35_K279_K1.1050.18
176_S388_I1.1040.18
509_T553_M1.1010.18
574_I577_Q1.1010.18
247_K254_E1.0990.18
267_A318_I1.0960.18
83_T184_S1.0900.18
180_L282_D1.0900.18
192_V340_S1.0890.18
413_M425_D1.0830.18
244_E437_I1.0820.18
217_I491_L1.0800.18
89_C526_A1.0770.18
73_E290_L1.0760.18
89_C440_Y1.0750.18
153_A156_E1.0730.17
180_L270_I1.0720.17
82_L170_A1.0700.17
286_V290_L1.0660.17
236_K369_E1.0640.17
314_T318_I1.0570.17
210_M315_A1.0530.17
82_L97_I1.0520.17
355_T533_I1.0500.17
213_L446_Y1.0490.17
20_M317_A1.0400.17
37_T211_T1.0290.17
97_I131_K1.0290.17
355_T423_E1.0270.17
247_K250_Q1.0260.17
178_L329_R1.0260.17
251_R259_V1.0220.16
236_K485_K1.0210.16
410_N454_G1.0100.16
432_E449_R1.0090.16
250_Q253_A1.0070.16
260_L314_T1.0060.16
175_K293_N1.0010.16
197_F508_L0.9960.16
247_K320_N0.9940.16
184_S210_M0.9930.16
483_L487_V0.9910.16
190_S194_H0.9880.16
215_R288_E0.9860.16
411_P455_G0.9800.16
213_L260_L0.9790.16
395_S448_S0.9780.16
452_T491_L0.9690.16
179_S207_A0.9660.15
124_A131_K0.9600.15
6_L262_E0.9600.15
472_V552_C0.9590.15
107_I167_L0.9560.15
296_A369_E0.9540.15
541_I556_V0.9530.15
61_C147_D0.9530.15
161_R560_K0.9520.15
513_P523_N0.9520.15
173_K426_A0.9510.15
279_K557_E0.9490.15
405_R411_P0.9480.15
397_A491_L0.9470.15
93_G304_H0.9460.15
413_M419_I0.9450.15
180_L448_S0.9420.15
131_K198_E0.9410.15
208_V213_L0.9410.15
403_K419_I0.9410.15
37_T103_R0.9400.15
153_A463_V0.9390.15
127_A331_P0.9390.15
41_L163_A0.9340.15
227_L258_A0.9330.15
127_A188_A0.9330.15
542_T545_S0.9310.15
219_Q309_Y0.9280.15
372_E579_Y0.9280.15
65_M292_Y0.9270.15
405_R453_E0.9250.15
176_S293_N0.9200.15
228_E232_A0.9180.15
84_I103_R0.9180.15
6_L54_E0.9160.15
509_T513_P0.9140.15
213_L270_I0.9140.15
82_L424_A0.9120.15
178_L273_M0.9110.15
49_C166_G0.9100.15
29_Q311_N0.9100.15
20_M219_Q0.9090.14
401_S427_C0.9070.14
262_E432_E0.9010.14
552_C569_A0.9000.14
360_A423_E0.8980.14
29_Q252_N0.8950.14
350_H569_A0.8930.14
355_T358_V0.8930.14
358_V450_F0.8920.14
232_A268_M0.8910.14
235_D257_R0.8900.14
358_V531_L0.8820.14
259_V289_S0.8800.14
533_I545_S0.8790.14
279_K283_I0.8780.14
244_E497_S0.8780.14
96_T99_M0.8760.14
59_D72_E0.8760.14
251_R255_Q0.8740.14
538_A560_K0.8730.14
220_K286_V0.8710.14
530_V536_V0.8700.14
69_A293_N0.8690.14
24_E312_G0.8690.14
173_K195_N0.8580.14
411_P423_E0.8570.14
112_G473_L0.8550.14
125_L159_L0.8540.14
322_S419_I0.8510.14
240_Y256_S0.8510.14
267_A395_S0.8510.14
410_N426_A0.8460.13
43_E286_V0.8450.13
150_S513_P0.8430.13
236_K268_M0.8430.13
412_T424_A0.8420.13
279_K282_D0.8410.13
22_V29_Q0.8400.13
218_D246_N0.8380.13
68_A321_S0.8370.13
261_R264_L0.8370.13
247_K251_R0.8370.13
40_L156_E0.8350.13
218_D583_Q0.8340.13
192_V454_G0.8330.13
105_K388_I0.8310.13
371_I387_I0.8300.13
412_T533_I0.8300.13
193_D283_I0.8260.13
79_N131_K0.8260.13
37_T104_P0.8260.13
208_V317_A0.8250.13
182_G465_I0.8220.13
40_L52_A0.8210.13
142_D466_I0.8200.13
572_M575_E0.8200.13
6_L225_A0.8190.13
371_I378_K0.8180.13
408_E458_F0.8170.13
210_M214_R0.8120.13
124_A242_E0.8120.13
32_N493_K0.8100.13
101_P105_K0.8100.13
207_A387_I0.8090.13
193_D585_Y0.8090.13
64_G129_S0.8080.13
46_R278_S0.8030.13
55_C179_S0.8030.13
94_S370_A0.8030.13
153_A254_E0.8000.13
84_I340_S0.8000.13
54_E85_T0.7980.13
207_A585_Y0.7970.13
283_I344_V0.7930.13
419_I424_A0.7910.13
486_D573_D0.7910.13
246_N249_Y0.7870.13
153_A182_G0.7870.13
321_S433_W0.7800.12
490_I569_A0.7800.12
42_T252_N0.7800.12
182_G207_A0.7780.12
14_V531_L0.7780.12
215_R221_I0.7780.12
371_I377_H0.7760.12
71_C309_Y0.7750.12
206_Q265_L0.7740.12
142_D523_N0.7740.12
20_M434_C0.7730.12
84_I446_Y0.7730.12
251_R572_M0.7690.12
576_G579_Y0.7680.12
137_S522_A0.7670.12
281_A585_Y0.7660.12
184_S358_V0.7660.12
43_E156_E0.7650.12
147_D258_A0.7640.12
267_A315_A0.7630.12
157_E516_D0.7620.12
37_T207_A0.7610.12
256_S536_V0.7610.12
6_L171_S0.7580.12
190_S440_Y0.7560.12
100_D103_R0.7540.12
227_L328_V0.7530.12
391_I503_W0.7520.12
422_Q579_Y0.7520.12
99_M190_S0.7510.12
169_V505_A0.7500.12
248_Q343_G0.7500.12
250_Q434_C0.7470.12
208_V433_W0.7460.12
44_K156_E0.7460.12
320_N575_E0.7460.12
55_C81_G0.7450.12
93_G120_Y0.7450.12
217_I262_E0.7430.12
370_A430_A0.7420.12
126_A479_W0.7420.12
320_N395_S0.7420.12
427_C433_W0.7410.12
278_S353_T0.7410.12
17_G312_G0.7410.12
21_G106_A0.7390.12
103_R133_I0.7380.12
569_A583_Q0.7380.12
328_V412_T0.7380.12
190_S304_H0.7380.12
153_A232_A0.7380.12
175_K413_M0.7370.12
267_A448_S0.7350.12
192_V203_M0.7340.12
72_E103_R0.7330.12
37_T81_G0.7320.12
221_I288_E0.7320.12
164_R507_R0.7320.12
105_K391_I0.7310.12
213_L268_M0.7310.12
39_A286_V0.7310.12
475_I526_A0.7300.12
210_M262_E0.7300.12
354_G562_Y0.7300.12
81_G103_R0.7290.12
439_E526_A0.7260.12
14_V180_L0.7260.12
74_K532_T0.7250.12
309_Y497_S0.7240.12
507_R511_K0.7240.12
304_H575_E0.7240.12
334_V424_A0.7230.12
39_A583_Q0.7230.12
126_A552_C0.7220.12
193_D278_S0.7210.12
552_C579_Y0.7200.12
495_T526_A0.7200.12
238_F317_A0.7200.12
496_N561_V0.7200.12
48_A330_E0.7180.12
317_A430_A0.7180.12
23_R27_E0.7160.12
292_Y561_V0.7150.12
419_I565_S0.7140.12
432_E497_S0.7120.11
22_V569_A0.7120.11
228_E467_K0.7120.11
126_A173_K0.7110.11
149_T237_N0.7100.11
396_A488_H0.7100.11
9_I515_T0.7090.11
105_K240_Y0.7090.11
479_W572_M0.7080.11
224_E579_Y0.7070.11
6_L354_G0.7050.11
345_A569_A0.7020.11
93_G439_E0.7000.11
210_M585_Y0.7000.11
321_S588_L0.6990.11
74_K516_D0.6990.11
166_G286_V0.6980.11
350_H387_I0.6970.11
47_H166_G0.6960.11
271_R501_T0.6930.11
271_R312_G0.6920.11
413_M585_Y0.6920.11
15_I85_T0.6920.11
37_T183_V0.6900.11
135_A529_G0.6900.11
372_E539_D0.6890.11
210_M234_A0.6890.11
334_V413_M0.6880.11
354_G522_A0.6870.11
250_Q516_D0.6860.11
254_E435_P0.6860.11
93_G99_M0.6850.11
61_C184_S0.6830.11
455_G461_T0.6830.11
61_C423_E0.6820.11
159_L163_A0.6820.11
270_I317_A0.6810.11
264_L460_M0.6810.11
21_G312_G0.6800.11
60_T566_A0.6800.11
397_A531_L0.6800.11
48_A355_T0.6780.11
14_V22_V0.6780.11
222_Y453_E0.6760.11
203_M273_M0.6760.11
384_E425_D0.6730.11
224_E228_E0.6720.11
42_T561_V0.6720.11
105_K565_S0.6680.11
558_E561_V0.6670.11
237_N419_I0.6670.11
208_V448_S0.6670.11
35_K420_S0.6660.11
360_A450_F0.6640.11
309_Y493_K0.6640.11
205_V449_R0.6640.11
36_A145_D0.6640.11
14_V36_A0.6640.11
304_H416_H0.6630.11
37_T71_C0.6630.11
71_C229_M0.6630.11
544_A572_M0.6620.11
270_I448_S0.6620.11
180_L496_N0.6610.11
234_A577_Q0.6600.11
33_M546_M0.6590.11
579_Y584_N0.6590.11
330_E355_T0.6590.11
174_G565_S0.6560.11
55_C417_W0.6560.11
55_C64_G0.6560.11
317_A427_C0.6550.11
28_E490_I0.6550.11
78_Q429_A0.6530.11
66_A70_A0.6530.11
131_K585_Y0.6530.11
106_A501_T0.6530.11
188_A349_G0.6520.11
198_E449_R0.6500.11
21_G501_T0.6500.11
424_A485_K0.6490.11
104_P395_S0.6480.11
79_N271_R0.6480.11
486_D583_Q0.6480.11
227_L261_R0.6480.11
147_D150_S0.6460.11
217_I505_A0.6460.11
572_M579_Y0.6440.11
180_L273_M0.6430.11
210_M572_M0.6420.11
213_L585_Y0.6420.11
17_G401_S0.6400.11
124_A466_I0.6400.11
395_S449_R0.6390.11
41_L441_F0.6390.11
565_S569_A0.6390.11
74_K343_G0.6390.11
64_G544_A0.6380.10
247_K435_P0.6350.10
170_A322_S0.6340.10
345_A552_C0.6330.10
235_D258_A0.6330.10
82_L124_A0.6330.10
411_P454_G0.6320.10
167_L179_S0.6290.10
174_G479_W0.6280.10
77_S131_K0.6280.10
275_Q492_N0.6270.10
63_A206_Q0.6270.10
250_Q418_E0.6260.10
100_D423_E0.6250.10
220_K429_A0.6250.10
22_V501_T0.6240.10
379_L439_E0.6230.10
146_A217_I0.6230.10
315_A569_A0.6220.10
388_I465_I0.6220.10
246_N583_Q0.6190.10
246_N438_H0.6190.10
123_A210_M0.6180.10
46_R289_S0.6170.10
246_N487_V0.6170.10
49_C60_T0.6160.10
505_A529_G0.6160.10
9_I173_K0.6160.10
168_A530_V0.6150.10
531_L536_V0.6150.10
311_N440_Y0.6140.10
14_V569_A0.6140.10
266_M312_G0.6130.10
52_A246_N0.6120.10
29_Q219_Q0.6120.10
166_G496_N0.6120.10
421_Q425_D0.6120.10
158_K314_T0.6110.10
246_N439_E0.6110.10
129_S388_I0.6090.10
345_A529_G0.6090.10
263_S315_A0.6090.10
328_V423_E0.6090.10
419_I532_T0.6090.10
17_G544_A0.6090.10
170_A329_R0.6080.10
105_K238_F0.6080.10
407_S423_E0.6080.10
210_M271_R0.6070.10
29_Q141_H0.6070.10
19_R281_A0.6070.10
472_V553_M0.6070.10
281_A572_M0.6060.10
128_H173_K0.6060.10
57_I74_K0.6060.10
6_L583_Q0.6060.10
249_Y253_A0.6050.10
317_A585_Y0.6040.10
179_S340_S0.6040.10
41_L71_C0.6020.10
184_S207_A0.6020.10
68_A458_F0.6020.10
82_L588_L0.6020.10
207_A273_M0.6010.10
194_H251_R0.6010.10
83_T104_P0.6000.10
165_A418_E0.6000.10
73_E76_S0.5970.10
210_M565_S0.5960.10
483_L488_H0.5960.10
179_S357_Q0.5960.10
169_V388_I0.5950.10
440_Y575_E0.5940.10
343_G493_K0.5940.10
127_A439_E0.5930.10
321_S356_A0.5930.10
103_R433_W0.5930.10
104_P584_N0.5920.10
238_F256_S0.5920.10
73_E77_S0.5910.10
246_N498_T0.5890.10
25_S63_A0.5890.10
104_P192_V0.5890.10
6_L497_S0.5880.10
296_A344_V0.5880.10
480_S483_L0.5880.10
442_R448_S0.5870.10
557_E560_K0.5870.10
180_L278_S0.5870.10
410_N583_Q0.5860.10
94_S149_T0.5850.10
240_Y314_T0.5850.10
38_A512_G0.5850.10
60_T78_Q0.5850.10
37_T65_M0.5840.10
64_G572_M0.5840.10
389_H492_N0.5830.10
231_L235_D0.5820.10
154_D356_A0.5820.10
469_L546_M0.5810.10
244_E585_Y0.5810.10
81_G179_S0.5800.10
72_E100_D0.5790.10
33_M242_E0.5780.10
22_V164_R0.5780.10
271_R454_G0.5780.10
28_E250_Q0.5770.10
173_K217_I0.5760.10
389_H503_W0.5760.10
124_A434_C0.5760.10
320_N467_K0.5760.10
473_L579_Y0.5760.10
48_A423_E0.5760.10
180_L585_Y0.5750.10
360_A453_E0.5750.10
483_L491_L0.5740.10
296_A410_N0.5740.10
172_M260_L0.5740.10
58_S70_A0.5740.10
321_S412_T0.5730.10
329_R357_Q0.5730.10
208_V585_Y0.5730.10
97_I480_S0.5730.10
281_A290_L0.5730.10
397_A461_T0.5730.10
469_L481_V0.5730.10
580_R583_Q0.5730.10
330_E552_C0.5720.10
38_A192_V0.5720.10
47_H52_A0.5710.10
288_E442_R0.5700.10
242_E496_N0.5700.10
379_L522_A0.5700.10
281_A454_G0.5700.10
321_S355_T0.5690.10
38_A74_K0.5690.10
570_H585_Y0.5690.10
198_E517_V0.5680.10
79_N261_R0.5680.10
429_A489_D0.5680.10
73_E171_S0.5670.10
375_T420_S0.5660.10
217_I345_A0.5660.10
179_S222_Y0.5650.10
419_I437_I0.5650.10
317_A321_S0.5640.10
190_S448_S0.5640.10
304_H354_G0.5640.10
8_K64_G0.5630.10
194_H207_A0.5630.10
60_T74_K0.5630.10
320_N579_Y0.5620.10
71_C205_V0.5610.10
232_A385_H0.5610.10
33_M418_E0.5610.10
434_C467_K0.5610.10
214_R217_I0.5610.10
400_G488_H0.5600.10
371_I418_E0.5600.10
345_A396_A0.5600.10
45_L160_L0.5600.10
259_V505_A0.5590.10
433_W446_Y0.5580.10
85_T365_Y0.5580.10
32_N248_Q0.5570.10
252_N385_H0.5570.10
8_K318_I0.5560.09
37_T41_L0.5560.09
501_T517_V0.5560.09
222_Y380_D0.5550.09
183_V191_I0.5540.09
94_S558_E0.5540.09
76_S384_E0.5540.09
385_H505_A0.5540.09
64_G68_A0.5530.09
213_L229_M0.5490.09
41_L210_M0.5490.09
250_Q469_L0.5480.09
273_M308_Q0.5470.09
329_R565_S0.5460.09
387_I501_T0.5460.09
213_L405_R0.5460.09
42_T54_E0.5450.09
472_V519_S0.5450.09
73_E126_A0.5440.09
350_H463_V0.5440.09
262_E449_R0.5430.09
476_A514_F0.5430.09
104_P435_P0.5430.09
141_H435_P0.5420.09
377_H387_I0.5420.09
380_D465_I0.5410.09
173_K292_Y0.5410.09
380_D559_T0.5410.09
350_H401_S0.5400.09
147_D175_K0.5400.09
174_G231_L0.5390.09
385_H559_T0.5390.09
38_A85_T0.5380.09
125_L131_K0.5370.09
15_I31_M0.5370.09
127_A379_L0.5360.09
256_S438_H0.5360.09
275_Q513_P0.5360.09
97_I214_R0.5360.09
73_E78_Q0.5350.09
442_R446_Y0.5340.09
197_F427_C0.5330.09
157_E539_D0.5330.09
102_T545_S0.5330.09
28_E560_K0.5320.09
511_K569_A0.5320.09
83_T333_V0.5310.09
49_C491_L0.5310.09
60_T166_G0.5310.09
83_T330_E0.5300.09
8_K78_Q0.5300.09
17_G64_G0.5300.09
24_E284_G0.5300.09
463_V473_L0.5300.09
519_S558_E0.5290.09
84_I197_F0.5280.09
229_M397_A0.5280.09
242_E482_E0.5270.09
94_S463_V0.5270.09
214_R490_I0.5270.09
61_C179_S0.5270.09
46_R282_D0.5270.09
349_G357_Q0.5260.09
389_H488_H0.5260.09
22_V311_N0.5260.09
395_S400_G0.5260.09
369_E491_L0.5250.09
289_S417_W0.5250.09
160_L579_Y0.5250.09
127_A557_E0.5250.09
448_S492_N0.5250.09
260_L318_I0.5240.09
102_T217_I0.5240.09
389_H433_W0.5240.09
182_G198_E0.5230.09
37_T47_H0.5220.09
509_T567_W0.5210.09
20_M164_R0.5210.09
501_T508_L0.5210.09
350_H423_E0.5210.09
293_N330_E0.5210.09
418_E458_F0.5190.09
36_A572_M0.5190.09
14_V421_Q0.5190.09
170_A308_Q0.5170.09
368_P492_N0.5160.09
190_S351_Q0.5160.09
319_L329_R0.5160.09
133_I569_A0.5160.09
304_H526_A0.5160.09
469_L566_A0.5150.09
218_D258_A0.5150.09
282_D479_W0.5150.09
263_S446_Y0.5150.09
225_A237_N0.5140.09
348_M466_I0.5140.09
237_N572_M0.5140.09
191_I455_G0.5140.09
85_T448_S0.5120.09
207_A315_A0.5120.09
260_L264_L0.5120.09
317_A396_A0.5110.09
264_L317_A0.5110.09
577_Q585_Y0.5110.09
217_I237_N0.5100.09
105_K448_S0.5090.09
65_M273_M0.5090.09
234_A314_T0.5090.09
508_L517_V0.5090.09
9_I426_A0.5080.09
196_F201_L0.5080.09
210_M569_A0.5080.09
99_M253_A0.5080.09
146_A439_E0.5070.09
435_P438_H0.5070.09
20_M29_Q0.5070.09
224_E279_K0.5070.09
244_E493_K0.5070.09
43_E463_V0.5070.09
208_V434_C0.5060.09
416_H479_W0.5060.09
271_R544_A0.5060.09
247_K584_N0.5050.09
199_S583_Q0.5050.09
247_K330_E0.5050.09
127_A455_G0.5050.09
388_I436_A0.5040.09
61_C380_D0.5040.09
546_M585_Y0.5040.09
278_S424_A0.5020.09
268_M328_V0.5010.09
22_V360_A0.5010.09
48_A102_T0.5010.09
190_S526_A0.5010.09
33_M529_G0.5000.09
247_K575_E0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1fuiA 5 1 100 0.393 Contact Map
3a9sA 5 0.9865 100 0.395 Contact Map
4f2dA 5 0.797 100 0.761 Contact Map
4lqlA 5 0.7614 100 0.763 Contact Map
3aekA 1 0.4585 55.6 0.988 Contact Map
1ycgA 5 0.3113 38.8 0.989 Contact Map
3lupA 1 0.181 37.6 0.989 Contact Map
2q9uA 3 0.3299 35 0.989 Contact Map
3gfsA 5 0.2538 32.2 0.989 Contact Map
3hlyA 1 0.2589 29.4 0.989 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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