LCFA - ECOLI - GREMLIN Contacts

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LCFA - Long-chain-fatty-acid--CoA ligase

UniProt:	P69451	Sequences: MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVNMGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAKGTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTTGVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELGGQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRIVDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSLTEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11530
Length:	561 (487)
Sequences:	70562 (50579)
Seq/√Len:	2291.9

ECOLI - LCFA AAS ENTF FADK ENTE ACSA PRPE CAIC MENE PAAK
BACSU - PPSE LCFA SRFAC DHBE LCFB ACSA YNGI YDAB YTCI MENE PPSB PPSC DLTA YHFT DHBF PKSJ PPSD SRFAA PKSN SRFAB
HALSA - Q9HRY8 Q9HSM3 Q9HQU8 Q9HNK0 Q9HQ43 Q9HQN8
SULSO - Q97VT6 Q97UX8 Q97U22 Q97YK9 Q97UW7 Q97VU7 Q97WQ0 Q97WQ9 Q97XW4 Q97WK0 Q97UF6 Q97V27 Q97WS5 Q980E4 Q97X52 Q97XW5 Q97VJ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
208_L	225_M	3.906	1.00
407_L	440_A	3.182	1.00
477_H	516_F	3.114	1.00
388_E	410_K	2.938	1.00
119_D	213_Y	2.910	1.00
59_R	96_R	2.909	1.00
421_R	424_A	2.886	1.00
227_T	416_L	2.797	1.00
75_D	123_S	2.779	1.00
71_L	99_M	2.770	1.00
78_A	122_A	2.757	1.00
441_V	449_R	2.670	1.00
55_E	96_R	2.658	1.00
43_V	278_Q	2.539	1.00
252_L	278_Q	2.426	1.00
406_E	435_H	2.422	1.00
121_G	420_Q	2.412	1.00
40_P	48_V	2.395	1.00
76_R	102_V	2.388	1.00
459_L	464_N	2.365	1.00
482_E	538_K	2.325	1.00
390_K	398_E	2.277	1.00
30_E	55_E	2.257	1.00
475_M	483_V	2.255	1.00
392_V	408_C	2.252	1.00
36_Y	39_Q	2.239	1.00
404_P	439_I	2.225	1.00
474_V	499_I	2.208	1.00
393_D	397_N	2.198	1.00
90_A	126_V	2.180	1.00
64_Y	69_L	2.142	1.00
119_D	421_R	2.126	1.00
57_R	89_V	2.119	1.00
32_S	36_Y	2.111	1.00
293_K	297_K	2.106	1.00
408_C	435_H	2.099	1.00
115_H	220_V	2.091	1.00
251_E	328_H	2.061	1.00
476_Q	520_Q	2.037	1.00
44_N	85_L	2.026	1.00
443_D	449_R	2.024	1.00
424_A	427_E	2.010	1.00
498_K	531_E	1.995	1.00
55_E	59_R	1.991	1.00
545_L	548_E	1.991	1.00
204_V	207_D	1.990	1.00
379_S	449_R	1.940	1.00
251_E	301_T	1.935	1.00
94_I	99_M	1.934	1.00
456_D	546_R	1.918	1.00
61_F	89_V	1.917	1.00
422_P	426_D	1.908	1.00
73_K	207_D	1.880	1.00
443_D	447_F	1.863	1.00
38_D	52_R	1.848	1.00
114_E	118_N	1.834	1.00
339_Q	343_E	1.809	1.00
390_K	408_C	1.807	1.00
441_V	451_V	1.798	1.00
43_V	48_V	1.786	1.00
74_G	207_D	1.775	1.00
72_K	75_D	1.771	1.00
66_Q	97_A	1.766	1.00
442_M	448_L	1.742	1.00
58_S	96_R	1.730	1.00
460_V	465_V	1.713	1.00
469_E	525_K	1.713	1.00
481_Q	504_K	1.707	1.00
548_E	551_D	1.693	1.00
31_Q	35_R	1.691	1.00
404_P	451_V	1.684	1.00
43_V	298_Y	1.682	1.00
299_P	326_S	1.682	1.00
52_R	56_E	1.682	1.00
475_M	482_E	1.673	1.00
82_P	128_V	1.672	1.00
227_T	230_N	1.635	1.00
401_P	442_M	1.630	1.00
471_E	485_A	1.620	1.00
88_P	269_C	1.595	1.00
423_D	427_E	1.587	1.00
208_L	416_L	1.586	1.00
95_L	209_A	1.583	1.00
78_A	104_V	1.581	1.00
486_V	500_F	1.580	1.00
50_T	53_K	1.569	1.00
500_F	549_L	1.566	1.00
485_A	499_I	1.564	1.00
391_L	440_A	1.557	1.00
502_V	536_L	1.553	1.00
148_I	152_M	1.538	1.00
280_L	300_F	1.531	1.00
352_Y	370_P	1.528	1.00
49_M	89_V	1.519	1.00
290_G	293_K	1.504	1.00
473_V	520_Q	1.500	1.00
305_G	310_F	1.499	1.00
32_S	35_R	1.488	1.00
239_N	275_L	1.486	1.00
59_R	63_A	1.481	1.00
37_A	52_R	1.479	1.00
366_V	409_V	1.472	1.00
479_G	512_S	1.468	1.00
77_V	94_I	1.466	1.00
40_P	43_V	1.464	1.00
120_S	213_Y	1.464	1.00
30_E	96_R	1.462	1.00
511_E	515_T	1.461	1.00
516_F	520_Q	1.456	1.00
400_P	403_Q	1.455	1.00
76_R	100_I	1.454	1.00
343_E	347_K	1.452	1.00
272_F	277_G	1.445	1.00
211_L	419_W	1.443	1.00
296_A	322_L	1.439	1.00
206_E	229_R	1.432	1.00
376_H	445_E	1.429	1.00
509_T	512_S	1.428	1.00
213_Y	223_G	1.427	1.00
501_V	532_F	1.426	1.00
503_K	532_F	1.423	1.00
251_E	302_A	1.419	1.00
254_V	300_F	1.419	1.00
40_P	278_Q	1.418	1.00
230_N	363_A	1.417	1.00
359_L	434_L	1.410	1.00
240_A	385_P	1.398	1.00
539_S	545_L	1.397	1.00
33_V	55_E	1.396	1.00
440_A	450_I	1.389	1.00
247_H	251_E	1.384	1.00
114_E	141_K	1.382	1.00
49_M	85_L	1.379	1.00
308_T	335_M	1.378	1.00
41_A	54_L	1.376	1.00
225_M	417_G	1.375	1.00
410_K	433_W	1.375	1.00
225_M	419_W	1.366	1.00
117_L	122_A	1.364	1.00
501_V	530_V	1.363	1.00
514_V	530_V	1.361	1.00
77_V	99_M	1.354	1.00
394_D	454_K	1.348	1.00
310_F	330_S	1.347	1.00
389_A	409_V	1.337	1.00
78_A	117_L	1.333	1.00
367_S	389_A	1.333	1.00
489_P	495_E	1.330	1.00
287_D	290_G	1.330	1.00
415_M	429_I	1.325	1.00
428_I	434_L	1.323	1.00
393_D	399_V	1.322	1.00
119_D	420_Q	1.319	1.00
205_P	229_R	1.316	1.00
404_P	441_V	1.316	1.00
61_F	93_G	1.314	1.00
74_G	416_L	1.304	1.00
64_Y	189_A	1.296	1.00
102_V	120_S	1.295	1.00
515_T	519_R	1.292	1.00
439_I	454_K	1.291	1.00
252_L	300_F	1.282	1.00
458_I	467_P	1.280	1.00
76_R	211_L	1.280	1.00
294_E	298_Y	1.279	1.00
44_N	47_E	1.277	1.00
332_G	337_V	1.266	1.00
100_I	208_L	1.255	1.00
76_R	419_W	1.254	1.00
71_L	77_V	1.252	1.00
376_H	447_F	1.248	1.00
382_L	447_F	1.247	1.00
490_S	496_A	1.241	1.00
48_V	298_Y	1.239	1.00
518_R	526_V	1.236	1.00
295_L	326_S	1.235	1.00
500_F	533_R	1.232	1.00
92_F	273_I	1.230	1.00
488_V	498_K	1.230	1.00
514_V	518_R	1.229	1.00
93_G	97_A	1.226	1.00
482_E	502_V	1.219	1.00
110_P	134_T	1.215	1.00
57_R	60_A	1.214	1.00
252_L	280_L	1.214	1.00
71_L	75_D	1.214	1.00
498_K	529_L	1.207	1.00
282_I	294_E	1.207	1.00
79_L	90_A	1.206	1.00
115_H	119_D	1.206	1.00
56_E	60_A	1.202	1.00
24_S	27_D	1.200	1.00
303_I	327_L	1.198	1.00
407_L	450_I	1.194	1.00
185_S	188_S	1.183	1.00
383_P	389_A	1.178	1.00
468_N	472_D	1.177	1.00
516_F	519_R	1.176	1.00
119_D	220_V	1.174	1.00
263_F	304_T	1.171	1.00
229_R	412_P	1.169	1.00
225_M	416_L	1.159	1.00
390_K	433_W	1.156	1.00
487_G	495_E	1.154	1.00
518_R	523_G	1.152	1.00
129_S	151_R	1.152	1.00
406_E	454_K	1.150	1.00
211_L	223_G	1.150	1.00
399_V	403_Q	1.149	1.00
54_L	92_F	1.148	1.00
104_V	113_L	1.147	1.00
214_T	224_A	1.146	1.00
55_E	198_Y	1.143	1.00
203_L	207_D	1.142	1.00
479_G	506_P	1.142	1.00
315_N	344_R	1.140	1.00
500_F	550_R	1.139	1.00
463_F	524_Y	1.136	1.00
110_P	114_E	1.134	1.00
496_A	528_K	1.134	1.00
369_N	447_F	1.123	1.00
118_N	220_V	1.122	1.00
302_A	329_L	1.113	1.00
110_P	137_K	1.111	1.00
499_I	530_V	1.109	1.00
503_K	508_L	1.108	1.00
456_D	468_N	1.107	1.00
61_F	126_V	1.104	1.00
30_E	59_R	1.102	1.00
53_K	56_E	1.100	1.00
71_L	124_A	1.094	1.00
230_N	414_V	1.094	1.00
226_L	230_N	1.088	1.00
57_R	86_Q	1.079	1.00
251_E	277_G	1.078	1.00
64_Y	68_G	1.075	1.00
41_A	51_F	1.071	1.00
47_E	85_L	1.070	1.00
49_M	57_R	1.069	1.00
387_T	413_Q	1.064	1.00
533_R	536_L	1.063	1.00
517_C	526_V	1.056	1.00
424_A	428_I	1.055	1.00
311_N	341_V	1.055	1.00
496_A	529_L	1.054	1.00
206_E	227_T	1.053	1.00
80_M	113_L	1.052	1.00
252_L	301_T	1.049	1.00
62_A	96_R	1.045	1.00
510_E	532_F	1.044	1.00
289_P	316_N	1.042	1.00
338_Q	341_V	1.039	1.00
87_Y	259_L	1.039	1.00
461_S	493_S	1.038	1.00
58_S	93_G	1.038	1.00
500_F	553_A	1.036	1.00
380_I	450_I	1.035	1.00
54_L	89_V	1.034	1.00
477_H	513_L	1.021	1.00
344_R	348_L	1.021	1.00
345_W	349_T	1.019	1.00
112_E	525_K	1.016	1.00
536_L	544_I	1.015	1.00
457_M	466_Y	1.012	1.00
408_C	433_W	1.012	1.00
409_V	436_T	1.011	1.00
253_V	272_F	1.005	1.00
75_D	99_M	1.005	1.00
115_H	213_Y	1.001	1.00
280_L	294_E	1.000	1.00
132_A	136_E	0.998	1.00
488_V	529_L	0.994	1.00
473_V	517_C	0.993	1.00
471_E	546_R	0.991	1.00
473_V	476_Q	0.987	1.00
224_A	415_M	0.985	1.00
458_I	497_V	0.982	1.00
43_V	280_L	0.981	1.00
40_P	50_T	0.981	1.00
367_S	448_L	0.979	1.00
369_N	379_S	0.976	1.00
510_E	530_V	0.975	1.00
257_L	263_F	0.974	1.00
391_L	399_V	0.973	1.00
69_L	146_H	0.968	1.00
547_R	551_D	0.963	1.00
215_G	541_V	0.962	1.00
533_R	552_E	0.961	1.00
76_R	121_G	0.959	1.00
439_I	452_D	0.955	1.00
68_G	194_Y	0.953	1.00
47_E	57_R	0.953	1.00
484_A	536_L	0.952	1.00
49_M	54_L	0.952	1.00
63_A	195_R	0.950	1.00
111_R	520_Q	0.949	1.00
233_A	386_S	0.948	1.00
212_Q	360_T	0.948	1.00
389_A	407_L	0.947	1.00
411_G	414_V	0.944	1.00
65_L	94_I	0.943	1.00
481_Q	502_V	0.943	1.00
233_A	412_P	0.940	1.00
42_F	88_P	0.940	1.00
389_A	448_L	0.936	1.00
522_T	525_K	0.934	1.00
512_S	515_T	0.934	1.00
39_Q	278_Q	0.933	1.00
337_V	342_A	0.933	1.00
29_F	33_V	0.930	1.00
46_G	297_K	0.928	1.00
280_L	298_Y	0.928	1.00
379_S	447_F	0.921	1.00
111_R	114_E	0.920	1.00
476_Q	516_F	0.918	1.00
108_Y	116_Q	0.917	1.00
548_E	552_E	0.916	1.00
115_H	118_N	0.913	1.00
85_L	89_V	0.911	1.00
61_F	90_A	0.907	1.00
78_A	125_I	0.906	1.00
81_M	84_L	0.900	1.00
124_A	146_H	0.897	1.00
235_L	274_E	0.896	1.00
489_P	492_S	0.896	1.00
314_L	344_R	0.895	1.00
105_N	260_Y	0.892	1.00
54_L	58_S	0.891	1.00
515_T	518_R	0.891	1.00
234_N	364_P	0.888	1.00
477_H	512_S	0.885	1.00
272_F	279_N	0.884	1.00
128_V	131_F	0.884	1.00
71_L	97_A	0.882	1.00
391_L	448_L	0.882	1.00
63_A	66_Q	0.878	1.00
340_V	344_R	0.875	1.00
460_V	487_G	0.873	1.00
66_Q	72_K	0.872	1.00
82_P	130_N	0.872	1.00
513_L	530_V	0.870	1.00
312_A	492_S	0.870	1.00
429_I	435_H	0.865	1.00
115_H	421_R	0.864	1.00
66_Q	199_V	0.863	1.00
376_H	443_D	0.862	1.00
91_L	101_V	0.861	1.00
55_E	58_S	0.860	1.00
407_L	448_L	0.858	1.00
63_A	199_V	0.858	1.00
111_R	115_H	0.858	1.00
79_L	101_V	0.856	1.00
26_V	203_L	0.856	1.00
133_H	136_E	0.855	1.00
226_L	363_A	0.854	1.00
344_R	347_K	0.854	1.00
65_L	126_V	0.853	1.00
81_M	150_T	0.852	1.00
310_F	345_W	0.851	1.00
430_K	435_H	0.851	1.00
31_Q	34_A	0.846	1.00
209_A	228_H	0.843	1.00
43_V	252_L	0.842	1.00
393_D	403_Q	0.839	1.00
94_I	101_V	0.839	1.00
479_G	504_K	0.837	1.00
69_L	124_A	0.836	1.00
304_T	365_L	0.832	1.00
86_Q	89_V	0.830	1.00
311_N	338_Q	0.830	1.00
56_E	196_M	0.828	1.00
362_C	434_L	0.828	1.00
53_K	57_R	0.825	1.00
286_R	309_L	0.824	1.00
252_L	299_P	0.821	1.00
296_A	323_D	0.819	1.00
329_L	354_L	0.817	1.00
262_I	359_L	0.815	1.00
30_E	34_A	0.815	1.00
331_A	356_G	0.813	1.00
42_F	85_L	0.812	1.00
91_L	265_L	0.809	1.00
62_A	97_A	0.808	1.00
208_L	227_T	0.807	1.00
226_L	415_M	0.806	1.00
396_D	408_C	0.805	1.00
28_M	236_E	0.801	1.00
402_G	444_E	0.797	1.00
89_V	93_G	0.796	1.00
512_S	516_F	0.796	1.00
484_A	549_L	0.794	1.00
506_P	509_T	0.792	1.00
47_E	86_Q	0.792	1.00
362_C	414_V	0.790	1.00
254_V	282_I	0.788	1.00
256_A	309_L	0.785	1.00
388_E	433_W	0.784	1.00
262_I	364_P	0.783	1.00
78_A	102_V	0.783	1.00
29_F	92_F	0.782	1.00
423_D	426_D	0.779	1.00
392_V	398_E	0.778	1.00
460_V	528_K	0.772	1.00
209_A	231_M	0.772	1.00
322_L	325_S	0.771	1.00
389_A	440_A	0.770	1.00
318_E	321_Q	0.769	1.00
129_S	152_M	0.768	1.00
306_V	309_L	0.768	1.00
40_P	44_N	0.768	1.00
500_F	552_E	0.766	1.00
510_E	514_V	0.763	1.00
301_T	328_H	0.763	1.00
54_L	88_P	0.762	1.00
425_T	429_I	0.762	1.00
289_P	293_K	0.762	1.00
88_P	281_L	0.762	1.00
57_R	85_L	0.757	1.00
394_D	406_E	0.757	1.00
116_Q	223_G	0.756	1.00
28_M	32_S	0.753	1.00
479_G	503_K	0.750	1.00
102_V	122_A	0.750	1.00
514_V	526_V	0.747	1.00
474_V	483_V	0.746	1.00
39_Q	248_P	0.746	1.00
329_L	352_Y	0.745	1.00
26_V	228_H	0.743	1.00
362_C	409_V	0.742	1.00
246_L	302_A	0.741	1.00
27_D	30_E	0.737	1.00
502_V	535_E	0.737	1.00
60_A	64_Y	0.735	1.00
310_F	332_G	0.732	1.00
421_R	425_T	0.729	1.00
63_A	194_Y	0.729	1.00
340_V	343_E	0.729	1.00
203_L	228_H	0.727	1.00
311_N	344_R	0.726	1.00
27_D	31_Q	0.726	1.00
484_A	544_I	0.725	1.00
290_G	294_E	0.723	1.00
94_I	97_A	0.723	1.00
29_F	55_E	0.723	1.00
210_F	226_L	0.720	1.00
80_M	131_F	0.720	1.00
327_L	330_S	0.719	1.00
26_V	95_L	0.718	1.00
460_V	497_V	0.717	1.00
38_D	50_T	0.716	1.00
63_A	196_M	0.716	1.00
337_V	353_L	0.715	1.00
263_F	333_G	0.715	1.00
80_M	125_I	0.715	1.00
511_E	514_V	0.715	1.00
266_T	304_T	0.713	1.00
440_A	448_L	0.713	1.00
435_H	454_K	0.713	1.00
46_G	298_Y	0.711	1.00
36_Y	52_R	0.711	1.00
261_H	463_F	0.711	1.00
81_M	87_Y	0.709	1.00
293_K	322_L	0.708	1.00
401_P	444_E	0.706	1.00
111_R	220_V	0.706	1.00
101_V	265_L	0.706	1.00
239_N	271_L	0.706	1.00
390_K	410_K	0.705	1.00
90_A	94_I	0.705	1.00
295_L	300_F	0.702	1.00
48_V	278_Q	0.700	1.00
127_I	131_F	0.700	1.00
91_L	95_L	0.699	1.00
456_D	471_E	0.697	1.00
481_Q	503_K	0.694	1.00
293_K	296_A	0.692	1.00
330_S	345_W	0.691	1.00
234_N	363_A	0.689	1.00
89_V	186_F	0.688	1.00
234_N	266_T	0.687	1.00
61_F	65_L	0.686	1.00
66_Q	201_P	0.685	1.00
84_L	128_V	0.684	1.00
81_M	126_V	0.683	1.00
501_V	513_L	0.683	1.00
121_G	419_W	0.683	1.00
517_C	521_L	0.682	1.00
241_T	385_P	0.680	1.00
125_I	135_L	0.680	1.00
488_V	496_A	0.679	1.00
33_V	37_A	0.679	1.00
254_V	294_E	0.679	1.00
362_C	366_V	0.678	1.00
473_V	516_F	0.676	1.00
508_L	513_L	0.675	1.00
296_A	325_S	0.674	1.00
523_G	526_V	0.674	1.00
356_G	365_L	0.674	1.00
72_K	123_S	0.673	1.00
62_A	93_G	0.673	1.00
486_V	553_A	0.673	1.00
311_N	315_N	0.672	1.00
247_H	328_H	0.671	1.00
64_Y	194_Y	0.671	1.00
467_P	485_A	0.668	1.00
26_V	30_E	0.666	1.00
78_A	120_S	0.665	1.00
440_A	451_V	0.664	1.00
127_I	149_L	0.664	1.00
498_K	553_A	0.663	1.00
481_Q	505_D	0.661	1.00
77_V	124_A	0.661	1.00
72_K	99_M	0.660	1.00
354_L	370_P	0.660	1.00
357_Y	366_V	0.655	1.00
467_P	546_R	0.655	1.00
230_N	416_L	0.654	1.00
304_T	356_G	0.654	1.00
414_V	434_L	0.654	1.00
391_L	442_M	0.653	1.00
28_M	232_L	0.653	1.00
60_A	196_M	0.651	1.00
119_D	419_W	0.650	1.00
384_V	387_T	0.649	1.00
480_V	501_V	0.646	1.00
32_S	276_G	0.645	1.00
295_L	303_I	0.644	1.00
51_F	277_G	0.643	1.00
393_D	396_D	0.643	1.00
255_T	268_N	0.642	1.00
135_L	138_V	0.641	1.00
136_E	139_V	0.640	1.00
253_V	302_A	0.640	1.00
236_E	240_A	0.640	1.00
124_A	148_I	0.640	1.00
468_N	471_E	0.638	1.00
390_K	431_N	0.638	1.00
65_L	124_A	0.638	1.00
134_T	137_K	0.637	1.00
61_F	64_Y	0.636	1.00
206_E	416_L	0.633	1.00
256_A	306_V	0.631	1.00
186_F	189_A	0.630	1.00
303_I	330_S	0.630	1.00
70_G	99_M	0.630	1.00
391_L	407_L	0.629	1.00
81_M	90_A	0.627	1.00
254_V	295_L	0.626	1.00
63_A	197_Q	0.625	1.00
198_Y	201_P	0.623	1.00
59_R	197_Q	0.622	1.00
282_I	291_L	0.620	1.00
480_V	483_V	0.619	1.00
73_K	201_P	0.618	1.00
320_Q	348_L	0.618	1.00
34_A	55_E	0.617	1.00
234_N	365_L	0.616	1.00
266_T	364_P	0.616	1.00
86_Q	128_V	0.614	1.00
49_M	53_K	0.613	1.00
58_S	62_A	0.613	1.00
59_R	198_Y	0.612	1.00
66_Q	198_Y	0.612	1.00
73_K	203_L	0.612	1.00
91_L	270_L	0.612	1.00
246_L	277_G	0.611	1.00
76_R	420_Q	0.611	1.00
380_I	440_A	0.609	1.00
336_P	450_I	0.609	1.00
109_T	112_E	0.609	1.00
489_P	493_S	0.609	1.00
415_M	428_I	0.608	1.00
495_E	550_R	0.608	1.00
484_A	546_R	0.607	1.00
317_K	321_Q	0.606	1.00
291_L	295_L	0.606	1.00
311_N	340_V	0.605	1.00
421_R	427_E	0.605	1.00
80_M	134_T	0.604	1.00
102_V	213_Y	0.602	1.00
537_P	549_L	0.602	1.00
460_V	493_S	0.601	1.00
81_M	127_I	0.598	1.00
66_Q	200_K	0.598	1.00
100_I	211_L	0.598	1.00
486_V	550_R	0.596	1.00
28_M	274_E	0.596	1.00
81_M	128_V	0.596	1.00
455_K	495_E	0.594	1.00
100_I	419_W	0.594	1.00
355_E	378_G	0.594	1.00
286_R	291_L	0.593	1.00
91_L	269_C	0.592	1.00
257_L	304_T	0.592	1.00
500_F	531_E	0.592	1.00
296_A	326_S	0.591	1.00
490_S	493_S	0.591	1.00
127_I	132_A	0.591	1.00
392_V	433_W	0.590	1.00
119_D	223_G	0.590	1.00
268_N	304_T	0.589	1.00
409_V	414_V	0.589	1.00
346_V	352_Y	0.589	1.00
266_T	365_L	0.589	1.00
58_S	61_F	0.589	1.00
220_V	421_R	0.589	1.00
210_F	231_M	0.588	1.00
148_I	151_R	0.585	1.00
470_I	497_V	0.584	1.00
103_N	212_Q	0.584	1.00
63_A	198_Y	0.581	1.00
92_F	270_L	0.580	1.00
490_S	494_G	0.580	1.00
247_H	301_T	0.580	1.00
253_V	277_G	0.580	1.00
36_Y	248_P	0.579	1.00
359_L	362_C	0.578	1.00
76_R	122_A	0.576	1.00
36_Y	276_G	0.576	1.00
292_V	324_F	0.576	1.00
42_F	279_N	0.575	1.00
131_F	134_T	0.575	1.00
482_E	536_L	0.574	1.00
80_M	135_L	0.573	1.00
531_E	552_E	0.573	1.00
472_D	476_Q	0.570	1.00
294_E	297_K	0.570	1.00
243_G	247_H	0.570	1.00
79_L	94_I	0.570	1.00
343_E	346_V	0.569	1.00
138_V	141_K	0.568	1.00
278_Q	298_Y	0.568	1.00
258_P	261_H	0.567	1.00
307_N	335_M	0.567	1.00
477_H	480_V	0.567	1.00
210_F	265_L	0.566	1.00
40_P	252_L	0.566	1.00
317_K	320_Q	0.566	1.00
341_V	344_R	0.564	1.00
337_V	355_E	0.563	1.00
60_A	63_A	0.563	1.00
402_G	441_V	0.561	1.00
359_L	436_T	0.560	1.00
467_P	487_G	0.560	1.00
479_G	516_F	0.558	1.00
219_G	466_Y	0.558	1.00
237_Q	241_T	0.557	1.00
234_N	238_V	0.556	1.00
417_G	422_P	0.556	1.00
473_V	521_L	0.553	1.00
514_V	517_C	0.553	1.00
474_V	517_C	0.553	1.00
256_A	305_G	0.551	1.00
404_P	454_K	0.551	1.00
211_L	225_M	0.550	1.00
59_R	66_Q	0.549	1.00
398_E	442_M	0.549	1.00
71_L	123_S	0.548	1.00
304_T	333_G	0.548	1.00
235_L	270_L	0.548	1.00
471_E	499_I	0.547	1.00
112_E	469_E	0.546	1.00
260_Y	463_F	0.544	1.00
526_V	530_V	0.543	1.00
422_P	425_T	0.542	1.00
255_T	281_L	0.542	1.00
43_V	46_G	0.541	1.00
367_S	380_I	0.541	1.00
79_L	87_Y	0.541	1.00
398_E	408_C	0.540	1.00
26_V	96_R	0.540	1.00
24_S	228_H	0.539	1.00
127_I	135_L	0.539	1.00
345_W	353_L	0.538	1.00
458_I	487_G	0.538	1.00
246_L	251_E	0.538	1.00
474_V	485_A	0.538	1.00
42_F	49_M	0.538	1.00
489_P	494_G	0.537	1.00
263_F	331_A	0.536	1.00
236_E	239_N	0.535	1.00
333_G	356_G	0.535	1.00
120_S	223_G	0.534	1.00
51_F	273_I	0.533	1.00
332_G	353_L	0.531	1.00
295_L	299_P	0.530	1.00
255_T	279_N	0.529	1.00
127_I	147_V	0.529	1.00
133_H	137_K	0.529	1.00
452_D	467_P	0.528	1.00
27_D	202_E	0.528	1.00
403_Q	441_V	0.528	1.00
207_D	228_H	0.528	1.00
333_G	365_L	0.527	1.00
236_E	274_E	0.527	1.00
120_S	211_L	0.526	1.00
343_E	377_S	0.524	1.00
321_Q	324_F	0.524	1.00
332_G	355_E	0.524	1.00
30_E	198_Y	0.523	1.00
188_S	191_H	0.522	1.00
135_L	139_V	0.518	1.00
460_V	495_E	0.518	1.00
289_P	318_E	0.517	1.00
301_T	326_S	0.517	1.00
429_I	434_L	0.517	1.00
252_L	255_T	0.515	1.00
356_G	368_V	0.515	1.00
237_Q	384_V	0.514	1.00
104_V	117_L	0.514	1.00
291_L	309_L	0.512	1.00
483_V	517_C	0.512	1.00
65_L	99_M	0.511	1.00
42_F	54_L	0.511	1.00
57_R	61_F	0.510	1.00
323_D	326_S	0.510	1.00
235_L	271_L	0.509	1.00
100_I	103_N	0.508	1.00
488_V	500_F	0.507	1.00
391_L	405_G	0.507	1.00
108_Y	260_Y	0.507	1.00
115_H	120_S	0.507	1.00
82_P	284_N	0.506	1.00
147_V	150_T	0.506	1.00
299_P	325_S	0.505	1.00
238_V	266_T	0.504	1.00
459_L	466_Y	0.503	1.00
255_T	264_A	0.501	1.00
263_F	356_G	0.500	1.00
392_V	396_D	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tsyA	2	0.754	100	0.152	Contact Map
3etcA	2	0.9002	100	0.159	Contact Map
1mdbA	1	0.934	100	0.159	Contact Map
3ni2A	1	0.9162	100	0.161	Contact Map
3o83A	1	0.7522	100	0.164	Contact Map
2d1sA	1	0.9269	100	0.168	Contact Map
3g7sA	2	0.8431	100	0.169	Contact Map
2v7bA	1	0.8627	100	0.17	Contact Map
1v25A	2	0.8681	100	0.175	Contact Map
2vsqA	1	0.9109	100	0.179	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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