GREMLIN Database
ATPL - ATP synthase subunit c
UniProt: P68699 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10102
Length: 79 (70)
Sequences: 627 (298)
Seq/√Len: 35.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_K37_E4.6051.00
63_I66_I2.9791.00
17_M67_A2.7911.00
46_I50_R2.1350.99
35_F49_L2.1000.99
28_I61_D1.9210.98
51_T55_I1.7940.97
24_A64_P1.7540.96
9_L12_A1.6790.95
32_G56_V1.5990.94
9_L74_V1.5470.92
69_G72_L1.5140.92
28_I32_G1.4720.90
54_F59_L1.4540.90
32_G57_M1.4460.90
17_M68_V1.4260.89
24_A28_I1.4110.88
39_A45_L1.4090.88
56_V60_V1.4050.88
11_M19_L1.3980.88
32_G61_D1.3850.88
31_L60_V1.3220.85
20_A67_A1.3070.84
13_A75_M1.2780.83
39_A52_Q1.2690.82
25_A36_L1.2430.81
12_A16_M1.2070.79
13_A29_G1.2050.79
37_E43_P1.2050.79
8_L11_M1.1680.77
35_F39_A1.0030.65
28_I60_V1.0010.65
20_A59_L0.9990.65
25_A39_A0.9960.65
31_L56_V0.9580.62
11_M18_G0.9480.61
32_G65_M0.9390.60
68_V72_L0.9100.58
52_Q67_A0.9040.57
33_G57_M0.9000.57
7_D10_Y0.8930.56
16_M61_D0.8920.56
55_I69_G0.8800.55
69_G73_Y0.8740.54
62_A69_G0.8730.54
12_A70_L0.8560.53
28_I62_A0.8550.53
41_R44_D0.8520.53
32_G53_F0.8490.52
59_L62_A0.8380.51
30_I33_G0.8260.50
14_A26_I0.8240.50
73_Y76_F0.8230.50
54_F72_L0.8230.50
20_A72_L0.8220.50
35_F62_A0.8210.50
20_A35_F0.8180.50
45_L49_L0.8180.50
35_F47_P0.8130.49
57_M60_V0.8080.49
44_D47_P0.7680.45
32_G60_V0.7620.45
39_A49_L0.7570.44
24_A63_I0.7550.44
48_L71_G0.7490.44
38_G49_L0.7480.44
15_V57_M0.7430.43
21_A63_I0.7390.43
36_L49_L0.7360.43
23_G58_G0.7200.41
24_A72_L0.7150.41
12_A15_V0.7090.40
52_Q56_V0.6990.40
22_I33_G0.6940.39
26_I30_I0.6870.39
24_A60_V0.6750.38
14_A63_I0.6720.37
55_I58_G0.6650.37
18_G56_V0.6540.36
45_L61_D0.6530.36
21_A26_I0.6380.35
36_L40_A0.6270.34
8_L12_A0.6170.33
67_A71_G0.6150.33
17_M69_G0.6120.33
42_Q61_D0.6080.32
65_M69_G0.6040.32
34_K58_G0.5980.32
55_I75_M0.5730.30
25_A31_L0.5530.28
17_M70_L0.5490.28
32_G59_L0.5390.27
41_R45_L0.5380.27
39_A50_R0.5350.27
28_I35_F0.5290.27
50_R73_Y0.5280.27
16_M67_A0.5230.26
16_M71_G0.5210.26
36_L39_A0.5100.25
40_A53_F0.5100.25
9_L71_G0.5100.25
9_L73_Y0.5090.25
35_F52_Q0.5040.25
10_Y14_A0.5010.25
30_I67_A0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1a91A 1 1 99.8 0.243 Contact Map
4v1gA 3 1 99.7 0.28 Contact Map
2xquA 3 1 99.7 0.289 Contact Map
3zk1A 5 0.9873 99.7 0.303 Contact Map
4cbkA 3 0.8734 99.7 0.305 Contact Map
4bemA 3 0.9873 99.7 0.313 Contact Map
4f4sA 3 0.9494 99.7 0.314 Contact Map
1wu0A 1 0.9114 99.7 0.315 Contact Map
2xndJ 3 0.9114 99.7 0.322 Contact Map
4bemJ 1 0.9873 99.6 0.337 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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