GREMLIN Database
RS21 - 30S ribosomal protein S21
UniProt: P68679 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10920
Length: 71 (58)
Sequences: 374 (106)
Seq/√Len: 13.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_E35_R4.6831.00
33_R36_E3.6980.99
43_T47_R3.1060.98
16_L45_R1.7840.72
34_R37_F1.7410.70
20_K29_L1.7230.69
42_T46_K1.6260.64
23_C28_V1.6110.64
20_K54_K1.5230.59
51_S58_K1.4040.53
17_R50_A1.3910.52
39_E47_R1.3640.51
21_R42_T1.3380.49
40_K46_K1.2660.45
9_N13_D1.2270.43
23_C36_E1.2260.43
2_P22_S1.1920.41
4_I24_E1.1470.39
2_P26_A1.1430.39
13_D22_S1.1360.38
15_A18_R1.1290.38
25_K51_S1.1220.38
4_I26_A1.1070.37
14_V28_V1.1010.37
13_D17_R1.0940.36
11_P28_V1.0710.35
39_E55_R1.0600.35
54_K58_K1.0490.34
52_A55_R1.0380.34
20_K25_K0.9990.32
42_T53_V0.9690.30
49_K53_V0.9470.29
17_R25_K0.9250.28
50_A53_V0.9050.28
33_R56_H0.9040.27
7_R32_V0.8990.27
12_F24_E0.8930.27
11_P14_V0.8910.27
3_V56_H0.8740.26
44_E50_A0.8730.26
34_R47_R0.8730.26
12_F50_A0.8570.25
15_A27_G0.8570.25
29_L32_V0.8470.25
6_V23_C0.8420.25
17_R32_V0.8270.24
40_K55_R0.8240.24
43_T48_A0.8220.24
31_E38_Y0.8160.24
26_A30_A0.8130.24
9_N49_K0.8000.23
2_P52_A0.7970.23
4_I23_C0.7860.23
22_S25_K0.7740.22
7_R22_S0.7680.22
7_R11_P0.7350.21
5_K23_C0.7290.21
4_I27_G0.7170.20
3_V7_R0.7140.20
2_P57_A0.7010.20
7_R10_E0.6890.19
48_A52_A0.6850.19
16_L19_F0.6830.19
14_V44_E0.6820.19
23_C37_F0.6820.19
51_S56_H0.6810.19
10_E18_R0.6760.19
9_N21_R0.6530.18
13_D54_K0.6520.18
24_E55_R0.6240.17
20_K37_F0.5990.16
26_A33_R0.5970.16
17_R46_K0.5960.16
24_E35_R0.5660.15
22_S28_V0.5660.15
8_E44_E0.5570.15
34_R42_T0.5540.15
25_K52_A0.5470.15
54_K57_A0.5370.15
25_K54_K0.5320.14
25_K30_A0.5170.14
30_A33_R0.5140.14
3_V21_R0.5140.14
11_P15_A0.5100.14
52_A58_K0.5060.14
3_V37_F0.5020.14
2_P20_K0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kiyU 1 0.7183 99.9 0.229 Contact Map
3bbnU 1 0.7465 99.8 0.3 Contact Map
4tp8U 1 0.7183 99.7 0.367 Contact Map
5aj3U 1 0.9859 99.7 0.394 Contact Map
2qpvA 2 0.3521 5.9 0.918 Contact Map
2ia0A 2 0.3944 4.3 0.923 Contact Map
2y4tA 1 0.4789 4.2 0.924 Contact Map
1w3iA 3 0.4366 4.2 0.924 Contact Map
4lurA 1 0.4789 3.9 0.925 Contact Map
2j3tD 1 0.3521 3.2 0.928 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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