GREMLIN Database
YBCO - Uncharacterized protein YbcO
UniProt: P68661 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13631
Length: 96 (92)
Sequences: 109 (75)
Seq/√Len: 7.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_A53_A3.7490.96
11_R91_E2.7760.82
60_E65_T2.3910.71
17_I76_C2.3830.71
52_I88_W2.3800.71
7_A52_I2.3340.69
31_A50_A2.2580.66
52_I93_V2.1850.64
4_L88_W2.1680.63
60_E63_R2.1200.61
22_N55_S1.9720.55
28_S52_I1.9670.55
20_V68_V1.8950.52
69_D72_Y1.8760.51
4_L12_E1.8400.50
5_R30_L1.7980.48
38_L49_I1.7840.48
7_A93_V1.7380.46
78_L82_A1.7140.45
60_E66_H1.6630.43
28_S88_W1.6480.42
88_W93_V1.5980.40
55_S59_D1.5920.40
34_R45_P1.5670.39
67_F73_A1.5250.37
23_G82_A1.4800.36
78_L81_M1.4600.35
2_A5_R1.4360.34
22_N26_E1.4250.34
3_D7_A1.4020.33
63_R66_H1.3620.32
60_E73_A1.3240.30
72_Y76_C1.3140.30
63_R68_V1.2020.26
25_P28_S1.1670.25
24_N65_T1.0960.23
33_I81_M1.0820.23
17_I24_N1.0820.23
63_R73_A1.0600.22
30_L50_A1.0470.22
15_V53_A1.0380.21
20_V30_L1.0350.21
50_A71_G1.0300.21
87_I94_I0.9760.20
11_R93_V0.9720.20
66_H73_A0.9480.19
2_A6_K0.9340.19
34_R37_G0.8800.17
79_E83_R0.8790.17
33_I82_A0.8690.17
13_C21_C0.8680.17
12_E92_G0.8660.17
31_A66_H0.8550.17
15_V80_G0.8480.17
39_C73_A0.8460.17
48_L89_L0.8430.17
68_V90_K0.8360.16
39_C43_T0.8290.16
59_D64_R0.8260.16
11_R77_A0.8180.16
87_I93_V0.8040.16
36_T49_I0.7930.16
61_I81_M0.7930.16
10_G24_N0.7850.15
20_V69_D0.7800.15
49_I74_K0.7730.15
10_G23_G0.7730.15
11_R52_I0.7670.15
2_A61_I0.7640.15
41_T45_P0.7640.15
15_V31_A0.7620.15
17_I61_I0.7490.15
54_C57_C0.7480.15
60_E69_D0.7430.14
27_T54_C0.7380.14
57_C62_D0.7230.14
75_E80_G0.7180.14
67_F71_G0.7170.14
17_I38_L0.7160.14
27_T59_D0.7100.14
18_P41_T0.7050.14
60_E67_F0.7050.14
4_L94_I0.7000.14
4_L52_I0.6990.14
63_R72_Y0.6980.14
3_D88_W0.6940.14
65_T94_I0.6930.14
42_G70_A0.6920.13
46_P86_V0.6870.13
34_R39_C0.6830.13
33_I51_T0.6810.13
43_T71_G0.6810.13
39_C45_P0.6720.13
39_C46_P0.6590.13
9_R59_D0.6550.13
77_A91_E0.6500.13
19_G38_L0.6500.13
28_S49_I0.6490.13
7_A88_W0.6460.13
46_P93_V0.6430.13
9_R53_A0.6400.13
20_V74_K0.6360.12
19_G29_V0.6310.12
55_S80_G0.6170.12
66_H70_A0.6170.12
54_C62_D0.6150.12
52_I91_E0.6140.12
57_C64_R0.6110.12
33_I45_P0.6080.12
67_F70_A0.6060.12
77_A81_M0.5960.12
9_R28_S0.5920.12
57_C84_T0.5830.12
6_K30_L0.5820.12
42_G84_T0.5760.11
2_A60_E0.5690.11
51_T77_A0.5640.11
72_Y75_E0.5630.11
13_C16_R0.5580.11
6_K11_R0.5530.11
18_P69_D0.5510.11
71_G78_L0.5500.11
33_I77_A0.5450.11
67_F75_E0.5450.11
7_A46_P0.5420.11
7_A38_L0.5410.11
34_R79_E0.5400.11
26_E55_S0.5380.11
37_G79_E0.5370.11
33_I78_L0.5310.11
9_R68_V0.5300.11
41_T48_L0.5290.11
19_G39_C0.5240.11
69_D73_A0.5200.11
22_N27_T0.5180.11
41_T94_I0.5060.10
12_E70_A0.5040.10
6_K52_I0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3g27A 2 0.8438 100 0.289 Contact Map
3plwA 1 0.7812 25.5 0.937 Contact Map
1i8oA 2 0.5625 14.7 0.944 Contact Map
1gnlA 1 0.8229 13.5 0.945 Contact Map
1cchA 1 0.5417 11.3 0.947 Contact Map
1w2lA 1 0.5833 9.5 0.949 Contact Map
4rknA 4 0.9479 9 0.949 Contact Map
1gntA 1 0.8229 8.3 0.95 Contact Map
3ob4A 2 0.25 7.9 0.95 Contact Map
1qn2A 1 0.5729 7.2 0.951 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0055 seconds.