XANQ - ECOLI - GREMLIN Contacts

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XANQ - Xanthine permease XanQ

UniProt:	P67444	Sequences: MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPALIVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIALGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGLSLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGLCVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGDITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGVASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGLKRRETLIVATSLGLGLGVSYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGYRQENVLPGITSAEEMD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13065
Length:	466 (405)
Sequences:	4406 (2290)
Seq/√Len:	113.8

ECOLI - XANQ UACT XANP YBBY URAA RUTG
BACSU - PBUX PUCK PUCJ YWDJ PYRP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
193_L	224_A	5.497	1.00
197_V	220_V	5.210	1.00
170_F	191_G	4.194	1.00
157_M	435_G	4.108	1.00
198_V	217_G	4.017	1.00
241_L	355_M	3.934	1.00
66_I	351_G	3.663	1.00
223_I	227_C	3.647	1.00
234_S	238_N	3.435	1.00
406_L	438_T	3.186	1.00
201_F	216_I	3.046	1.00
131_L	263_G	2.986	1.00
190_V	225_S	2.961	1.00
233_F	236_M	2.892	1.00
69_G	348_V	2.826	1.00
248_F	313_A	2.796	1.00
403_S	439_A	2.698	1.00
395_R	447_P	2.688	1.00
193_L	220_V	2.679	1.00
193_L	197_V	2.676	1.00
239_L	355_M	2.639	1.00
190_V	230_M	2.577	1.00
126_F	312_S	2.534	1.00
277_I	300_G	2.458	1.00
32_L	346_M	2.450	1.00
71_G	307_V	2.445	1.00
28_A	342_T	2.423	1.00
189_G	193_L	2.362	1.00
122_L	312_S	2.309	1.00
120_S	253_S	2.297	1.00
195_L	374_L	2.259	1.00
219_C	223_I	2.238	1.00
25_L	346_M	2.237	1.00
222_Y	231_V	2.222	1.00
190_V	228_L	2.214	1.00
24_A	342_T	2.176	1.00
282_M	389_T	2.173	1.00
73_W	344_A	2.154	1.00
67_A	314_V	2.144	1.00
73_W	341_R	2.111	1.00
126_F	309_V	2.087	1.00
145_V	444_I	2.079	1.00
236_M	359_F	2.068	1.00
223_I	226_L	2.054	1.00
237_R	240_P	2.054	1.00
185_Y	189_G	2.050	1.00
334_V	339_V	1.984	1.00
76_V	341_R	1.972	1.00
46_V	100_M	1.931	1.00
186_E	230_M	1.902	1.00
66_I	348_V	1.888	1.00
235_S	362_T	1.884	1.00
441_L	445_I	1.875	1.00
197_V	201_F	1.873	1.00
119_S	253_S	1.870	1.00
222_Y	362_T	1.869	1.00
197_V	224_A	1.839	1.00
224_A	228_L	1.835	1.00
198_V	371_A	1.832	1.00
345_V	349_I	1.812	1.00
160_L	380_A	1.807	1.00
16_E	286_R	1.803	1.00
126_F	130_F	1.797	1.00
201_F	205_R	1.765	1.00
147_T	443_N	1.754	1.00
239_L	358_G	1.739	1.00
227_C	230_M	1.716	1.00
32_L	343_I	1.688	1.00
234_S	237_R	1.684	1.00
169_D	365_S	1.675	1.00
236_M	239_L	1.633	1.00
287_P	290_G	1.623	1.00
133_V	309_V	1.616	1.00
200_G	204_C	1.609	1.00
208_L	212_G	1.577	1.00
130_F	134_G	1.562	1.00
195_L	402_T	1.544	1.00
296_R	299_G	1.539	1.00
399_I	442_L	1.536	1.00
189_G	192_L	1.525	1.00
255_S	258_Q	1.517	1.00
68_S	89_I	1.510	1.00
119_S	254_F	1.497	1.00
192_L	196_I	1.496	1.00
126_F	129_A	1.492	1.00
18_R	338_Y	1.487	1.00
149_T	400_V	1.481	1.00
221_G	367_V	1.479	1.00
403_S	438_T	1.475	1.00
205_R	209_L	1.466	1.00
101_I	104_G	1.459	1.00
209_L	216_I	1.447	1.00
14_E	286_R	1.436	1.00
121_L	124_V	1.428	1.00
226_L	233_F	1.409	1.00
437_L	441_L	1.406	1.00
224_A	227_C	1.403	1.00
73_W	76_V	1.402	1.00
247_P	315_G	1.401	1.00
286_R	296_R	1.401	1.00
103_L	258_Q	1.399	1.00
248_F	251_G	1.388	1.00
31_H	325_N	1.365	1.00
119_S	251_G	1.363	1.00
235_S	238_N	1.357	1.00
406_L	434_A	1.356	1.00
129_A	302_L	1.353	1.00
104_G	121_L	1.344	1.00
70_I	348_V	1.338	1.00
425_Y	429_E	1.337	1.00
422_A	425_Y	1.331	1.00
254_F	259_F	1.329	1.00
329_I	335_A	1.322	1.00
196_I	200_G	1.319	1.00
129_A	309_V	1.315	1.00
97_V	101_I	1.301	1.00
73_W	348_V	1.301	1.00
72_T	89_I	1.298	0.99
276_D	323_A	1.297	0.99
22_H	26_V	1.290	0.99
249_K	315_G	1.287	0.99
136_S	298_K	1.282	0.99
35_I	39_M	1.281	0.99
77_N	341_R	1.278	0.99
220_V	224_A	1.277	0.99
280_T	329_I	1.274	0.99
14_E	17_D	1.269	0.99
13_F	17_D	1.257	0.99
107_M	255_S	1.251	0.99
120_S	124_V	1.251	0.99
247_P	313_A	1.250	0.99
133_V	305_G	1.244	0.99
186_E	228_L	1.235	0.99
66_I	314_V	1.228	0.99
100_M	121_L	1.227	0.99
76_V	340_G	1.226	0.99
186_E	189_G	1.219	0.99
402_T	438_T	1.212	0.99
355_M	358_G	1.202	0.99
212_G	216_I	1.198	0.99
123_G	254_F	1.197	0.99
205_R	210_R	1.192	0.99
173_G	183_G	1.182	0.99
175_A	181_T	1.182	0.99
133_V	306_L	1.177	0.99
93_N	269_S	1.164	0.99
119_S	123_G	1.162	0.99
128_G	266_Y	1.159	0.99
181_T	184_N	1.155	0.99
83_G	299_G	1.152	0.99
129_A	136_S	1.150	0.99
289_Q	296_R	1.149	0.99
123_G	259_F	1.148	0.99
149_T	153_I	1.141	0.99
167_I	409_G	1.140	0.99
133_V	137_F	1.140	0.99
88_S	280_T	1.139	0.99
171_G	182_F	1.137	0.99
349_I	353_F	1.133	0.99
284_S	287_P	1.128	0.99
189_G	228_L	1.127	0.99
243_T	354_P	1.116	0.98
256_F	259_F	1.113	0.98
60_L	246_H	1.108	0.98
125_S	129_A	1.104	0.98
281_A	288_I	1.102	0.98
120_S	125_S	1.099	0.98
108_K	120_S	1.093	0.98
273_A	277_I	1.076	0.98
82_V	306_L	1.075	0.98
390_N	396_E	1.072	0.98
311_A	319_L	1.065	0.98
187_H	366_A	1.062	0.98
216_I	220_V	1.061	0.98
21_F	25_L	1.056	0.98
95_S	269_S	1.055	0.98
91_S	322_F	1.054	0.98
277_I	304_D	1.048	0.98
272_E	320_T	1.046	0.98
157_M	407_G	1.045	0.98
404_L	408_L	1.044	0.98
385_R	389_T	1.037	0.98
48_A	59_Y	1.033	0.97
90_Q	321_T	1.032	0.97
276_D	326_N	1.028	0.97
353_F	357_G	1.027	0.97
89_I	343_I	1.026	0.97
99_V	265_I	1.023	0.97
127_V	259_F	1.019	0.97
103_L	262_V	1.017	0.97
222_Y	233_F	1.017	0.97
424_I	427_L	1.015	0.97
34_A	328_V	1.014	0.97
13_F	19_P	1.011	0.97
241_L	353_F	1.009	0.97
19_P	336_S	1.006	0.97
73_W	345_V	0.993	0.97
200_G	445_I	0.991	0.97
393_K	396_E	0.990	0.97
424_I	428_V	0.989	0.97
184_N	187_H	0.982	0.97
156_L	404_L	0.982	0.97
125_S	312_S	0.980	0.96
123_G	127_V	0.980	0.96
225_S	229_G	0.979	0.96
70_I	310_I	0.973	0.96
186_E	190_V	0.973	0.96
19_P	24_A	0.971	0.96
182_F	413_D	0.970	0.96
44_L	61_V	0.968	0.96
338_Y	341_R	0.966	0.96
42_P	94_F	0.965	0.96
226_L	231_V	0.963	0.96
193_L	228_L	0.961	0.96
310_I	314_V	0.957	0.96
19_P	339_V	0.955	0.96
246_H	249_K	0.954	0.96
18_R	24_A	0.950	0.96
20_P	23_Q	0.948	0.96
102_A	106_S	0.944	0.96
88_S	321_T	0.941	0.96
163_I	405_G	0.932	0.95
134_G	138_I	0.932	0.95
398_L	402_T	0.929	0.95
168_I	182_F	0.926	0.95
125_S	132_V	0.921	0.95
102_A	105_S	0.913	0.95
196_I	199_I	0.912	0.95
171_G	183_G	0.910	0.95
232_D	235_S	0.907	0.95
13_F	20_P	0.906	0.95
131_L	270_V	0.905	0.95
273_A	300_G	0.904	0.95
172_G	182_F	0.900	0.94
286_R	289_Q	0.895	0.94
244_I	352_L	0.893	0.94
25_L	29_I	0.892	0.94
29_I	346_M	0.892	0.94
15_L	18_R	0.891	0.94
124_V	132_V	0.891	0.94
124_V	128_G	0.888	0.94
31_H	35_I	0.884	0.94
257_H	261_V	0.879	0.94
197_V	216_I	0.874	0.93
172_G	183_G	0.870	0.93
140_P	298_K	0.869	0.93
241_L	245_P	0.868	0.93
161_S	432_I	0.867	0.93
93_N	320_T	0.865	0.93
380_A	404_L	0.862	0.93
70_I	74_L	0.860	0.93
356_I	359_F	0.858	0.93
290_G	295_S	0.855	0.93
123_G	136_S	0.852	0.93
106_S	109_S	0.852	0.93
284_S	335_A	0.849	0.92
25_L	342_T	0.848	0.92
197_V	200_G	0.843	0.92
341_R	344_A	0.840	0.92
169_D	376_F	0.839	0.92
156_L	384_I	0.838	0.92
69_G	344_A	0.838	0.92
306_L	310_I	0.838	0.92
244_I	247_P	0.836	0.92
89_I	340_G	0.829	0.92
146_I	436_G	0.827	0.91
273_A	304_D	0.826	0.91
381_I	397_T	0.825	0.91
236_M	355_M	0.823	0.91
233_F	362_T	0.821	0.91
122_L	125_S	0.821	0.91
31_H	34_A	0.821	0.91
118_M	122_L	0.819	0.91
127_V	254_F	0.817	0.91
132_V	136_S	0.813	0.91
225_S	230_M	0.813	0.91
206_S	210_R	0.811	0.91
25_L	237_R	0.809	0.91
222_Y	363_I	0.799	0.90
236_M	358_G	0.799	0.90
141_Y	290_G	0.796	0.90
32_L	350_L	0.796	0.90
121_L	125_S	0.795	0.90
35_I	325_N	0.794	0.90
192_L	228_L	0.793	0.90
67_A	316_S	0.792	0.90
81_I	306_L	0.790	0.89
231_V	362_T	0.789	0.89
64_A	317_L	0.787	0.89
123_G	128_G	0.785	0.89
129_A	305_G	0.783	0.89
274_V	297_L	0.782	0.89
240_P	243_T	0.782	0.89
350_L	356_I	0.781	0.89
374_L	398_L	0.781	0.89
132_V	302_L	0.780	0.89
223_I	349_I	0.779	0.89
38_P	376_F	0.778	0.89
75_Q	86_L	0.776	0.89
110_D	253_S	0.772	0.88
341_R	345_V	0.770	0.88
88_S	328_V	0.770	0.88
120_S	255_S	0.768	0.88
195_L	199_I	0.768	0.88
76_V	337_R	0.767	0.88
67_A	311_A	0.762	0.88
123_G	129_A	0.760	0.88
38_P	324_Q	0.760	0.88
173_G	182_F	0.759	0.88
155_V	276_D	0.758	0.87
41_T	169_D	0.757	0.87
269_S	320_T	0.757	0.87
88_S	277_I	0.753	0.87
381_I	400_V	0.753	0.87
281_A	289_Q	0.752	0.87
399_I	403_S	0.752	0.87
87_L	340_G	0.751	0.87
109_S	117_I	0.749	0.87
42_P	92_V	0.749	0.87
401_A	405_G	0.749	0.87
39_M	68_S	0.748	0.87
153_I	403_S	0.747	0.87
215_A	219_C	0.743	0.86
149_T	396_E	0.743	0.86
219_C	359_F	0.739	0.86
27_G	31_H	0.739	0.86
410_V	434_A	0.738	0.86
107_M	110_D	0.736	0.86
98_T	101_I	0.734	0.86
309_V	313_A	0.734	0.86
326_N	329_I	0.733	0.86
145_V	440_I	0.732	0.86
67_A	310_I	0.731	0.86
190_V	224_A	0.730	0.85
169_D	368_L	0.728	0.85
128_G	132_V	0.727	0.85
201_F	209_L	0.726	0.85
346_M	350_L	0.726	0.85
273_A	320_T	0.726	0.85
308_S	319_L	0.724	0.85
247_P	252_F	0.723	0.85
166_G	191_G	0.722	0.85
95_S	375_M	0.721	0.85
217_G	220_V	0.721	0.85
133_V	302_L	0.720	0.85
196_I	219_C	0.719	0.85
66_I	247_P	0.718	0.84
402_T	442_L	0.717	0.84
267_L	271_L	0.717	0.84
214_I	328_V	0.711	0.84
267_L	279_A	0.710	0.84
44_L	47_G	0.709	0.84
28_A	343_I	0.709	0.84
92_V	96_F	0.707	0.84
140_P	144_R	0.707	0.84
395_R	399_I	0.705	0.83
295_S	299_G	0.702	0.83
332_T	346_M	0.702	0.83
74_L	81_I	0.701	0.83
156_L	387_I	0.700	0.83
64_A	68_S	0.699	0.83
137_F	302_L	0.697	0.83
47_G	60_L	0.697	0.83
97_V	267_L	0.696	0.83
218_L	271_L	0.695	0.83
263_G	266_Y	0.691	0.82
168_I	171_G	0.690	0.82
225_S	228_L	0.690	0.82
197_V	217_G	0.690	0.82
39_M	64_A	0.690	0.82
388_I	392_L	0.689	0.82
256_F	260_L	0.688	0.82
236_M	362_T	0.687	0.82
123_G	126_F	0.686	0.82
117_I	121_L	0.686	0.82
125_S	128_G	0.685	0.82
174_F	181_T	0.684	0.82
63_M	67_A	0.683	0.81
141_Y	145_V	0.681	0.81
44_L	368_L	0.680	0.81
358_G	361_T	0.679	0.81
62_S	357_G	0.679	0.81
406_L	410_V	0.677	0.81
21_F	346_M	0.676	0.81
74_L	303_A	0.676	0.81
15_L	19_P	0.674	0.81
66_I	249_K	0.673	0.80
211_M	447_P	0.667	0.80
120_S	123_G	0.667	0.80
122_L	128_G	0.666	0.80
64_A	92_V	0.664	0.80
431_P	435_G	0.664	0.80
124_V	129_A	0.664	0.80
132_V	269_S	0.663	0.79
228_L	356_I	0.663	0.79
66_I	352_L	0.660	0.79
161_S	430_N	0.656	0.79
218_L	371_A	0.654	0.79
63_M	66_I	0.653	0.78
399_I	447_P	0.652	0.78
182_F	185_Y	0.652	0.78
280_T	326_N	0.650	0.78
407_G	431_P	0.647	0.78
37_V	43_A	0.646	0.78
289_Q	295_S	0.645	0.78
377_S	381_I	0.644	0.77
239_L	354_P	0.643	0.77
269_S	272_E	0.642	0.77
41_T	44_L	0.639	0.77
190_V	366_A	0.639	0.77
280_T	321_T	0.639	0.77
132_V	266_Y	0.638	0.77
90_Q	273_A	0.637	0.77
201_F	220_V	0.635	0.77
189_G	224_A	0.633	0.76
46_V	218_L	0.631	0.76
48_A	217_G	0.630	0.76
209_L	213_G	0.628	0.76
272_E	304_D	0.628	0.76
107_M	258_Q	0.627	0.76
119_S	122_L	0.619	0.75
35_I	89_I	0.615	0.74
304_D	401_A	0.615	0.74
226_L	445_I	0.613	0.74
101_I	105_S	0.613	0.74
136_S	302_L	0.611	0.74
31_H	328_V	0.610	0.74
84_S	296_R	0.610	0.74
37_V	324_Q	0.609	0.73
149_T	399_I	0.608	0.73
211_M	392_L	0.607	0.73
261_V	427_L	0.606	0.73
103_L	107_M	0.606	0.73
35_I	385_R	0.605	0.73
283_V	330_Q	0.605	0.73
93_N	96_F	0.605	0.73
235_S	314_V	0.604	0.73
170_F	373_T	0.604	0.73
201_F	217_G	0.604	0.73
95_S	158_I	0.603	0.73
45_I	101_I	0.602	0.73
407_G	435_G	0.601	0.73
128_G	135_S	0.600	0.72
17_D	336_S	0.600	0.72
400_V	404_L	0.600	0.72
334_V	368_L	0.600	0.72
188_L	192_L	0.598	0.72
183_G	187_H	0.597	0.72
182_F	187_H	0.597	0.72
163_I	401_A	0.597	0.72
245_P	374_L	0.596	0.72
220_V	223_I	0.595	0.72
39_M	42_P	0.595	0.72
358_G	362_T	0.593	0.72
216_I	219_C	0.591	0.71
69_G	73_W	0.590	0.71
28_A	155_V	0.588	0.71
95_S	320_T	0.588	0.71
155_V	158_I	0.587	0.71
127_V	131_L	0.586	0.71
290_G	296_R	0.586	0.71
147_T	327_G	0.586	0.71
244_I	351_G	0.586	0.71
184_N	189_G	0.585	0.71
330_Q	385_R	0.584	0.70
148_P	397_T	0.584	0.70
100_M	262_V	0.580	0.70
163_I	408_L	0.580	0.70
71_G	303_A	0.577	0.69
275_G	407_G	0.577	0.69
18_R	21_F	0.576	0.69
120_S	258_Q	0.575	0.69
242_I	353_F	0.575	0.69
66_I	333_G	0.573	0.69
440_I	448_G	0.573	0.69
61_V	361_T	0.573	0.69
308_S	311_A	0.572	0.69
187_H	331_M	0.571	0.69
279_A	382_A	0.571	0.69
300_G	304_D	0.570	0.69
86_L	300_G	0.568	0.68
198_V	202_N	0.568	0.68
395_R	448_G	0.567	0.68
152_G	383_G	0.567	0.68
130_F	133_V	0.566	0.68
214_I	285_R	0.566	0.68
423_S	426_V	0.566	0.68
205_R	208_L	0.566	0.68
324_Q	376_F	0.565	0.68
222_Y	226_L	0.565	0.68
173_G	351_G	0.565	0.68
323_A	382_A	0.564	0.68
200_G	205_R	0.563	0.68
60_L	75_Q	0.562	0.67
68_S	88_S	0.561	0.67
132_V	270_V	0.561	0.67
67_A	307_V	0.561	0.67
98_T	102_A	0.560	0.67
168_I	174_F	0.557	0.67
165_V	169_D	0.557	0.67
202_N	398_L	0.557	0.67
134_G	240_P	0.557	0.67
276_D	321_T	0.556	0.67
90_Q	308_S	0.556	0.67
435_G	439_A	0.555	0.67
123_G	132_V	0.555	0.67
158_I	322_F	0.555	0.67
247_P	251_G	0.554	0.66
387_I	390_N	0.554	0.66
385_R	393_K	0.554	0.66
122_L	131_L	0.554	0.66
266_Y	308_S	0.554	0.66
351_G	357_G	0.553	0.66
276_D	382_A	0.551	0.66
218_L	368_L	0.551	0.66
223_I	242_I	0.550	0.66
118_M	121_L	0.549	0.66
169_D	372_M	0.549	0.66
104_G	117_I	0.549	0.66
15_L	336_S	0.548	0.66
163_I	373_T	0.547	0.65
146_I	207_P	0.546	0.65
72_T	344_A	0.545	0.65
226_L	229_G	0.544	0.65
144_R	444_I	0.542	0.65
43_A	47_G	0.540	0.64
100_M	104_G	0.540	0.64
141_Y	146_I	0.540	0.64
154_V	195_L	0.539	0.64
405_G	408_L	0.539	0.64
440_I	444_I	0.538	0.64
309_V	312_S	0.538	0.64
186_E	224_A	0.538	0.64
392_L	400_V	0.537	0.64
92_V	320_T	0.537	0.64
207_P	210_R	0.536	0.64
87_L	284_S	0.536	0.64
73_W	77_N	0.536	0.64
304_D	320_T	0.535	0.64
306_L	341_R	0.535	0.64
63_M	122_L	0.534	0.64
107_M	117_I	0.532	0.63
126_F	252_F	0.532	0.63
269_S	277_I	0.531	0.63
202_N	210_R	0.530	0.63
274_V	278_T	0.530	0.63
377_S	397_T	0.529	0.63
70_I	314_V	0.529	0.63
41_T	45_I	0.528	0.63
27_G	146_I	0.528	0.63
29_I	171_G	0.527	0.63
286_R	290_G	0.527	0.63
151_S	354_P	0.527	0.63
202_N	331_M	0.526	0.62
195_L	407_G	0.526	0.62
40_V	61_V	0.525	0.62
82_V	155_V	0.525	0.62
368_L	371_A	0.524	0.62
47_G	284_S	0.524	0.62
96_F	308_S	0.524	0.62
219_C	445_I	0.524	0.62
139_L	274_V	0.523	0.62
183_G	408_L	0.523	0.62
325_N	328_V	0.523	0.62
92_V	276_D	0.522	0.62
183_G	188_L	0.522	0.62
68_S	265_I	0.521	0.62
446_L	449_G	0.521	0.62
273_A	321_T	0.521	0.62
240_P	355_M	0.520	0.62
171_G	174_F	0.519	0.61
21_F	345_V	0.518	0.61
380_A	384_I	0.517	0.61
267_L	440_I	0.517	0.61
135_S	301_V	0.517	0.61
72_T	320_T	0.516	0.61
161_S	431_P	0.515	0.61
156_L	380_A	0.515	0.61
337_R	341_R	0.514	0.61
21_F	24_A	0.513	0.60
122_L	309_V	0.512	0.60
166_G	194_V	0.512	0.60
170_F	174_F	0.512	0.60
134_G	441_L	0.512	0.60
306_L	309_V	0.511	0.60
288_I	296_R	0.511	0.60
39_M	347_L	0.510	0.60
246_H	312_S	0.510	0.60
402_T	408_L	0.510	0.60
203_C	381_I	0.509	0.60
129_A	132_V	0.509	0.60
168_I	219_C	0.509	0.60
433_C	437_L	0.509	0.60
173_G	187_H	0.508	0.60
287_P	295_S	0.508	0.60
223_I	237_R	0.508	0.60
381_I	384_I	0.507	0.60
19_P	338_Y	0.507	0.60
280_T	360_F	0.506	0.59
229_G	367_V	0.505	0.59
381_I	401_A	0.505	0.59
346_M	437_L	0.503	0.59
270_V	319_L	0.502	0.59
153_I	439_A	0.502	0.59
121_L	132_V	0.501	0.59
193_L	227_C	0.500	0.59
159_G	166_G	0.500	0.59
63_M	315_G	0.500	0.59

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qe7A	2	0.8541	100	0.439	Contact Map
1pw4A	1	0.8755	95.4	0.948	Contact Map
4ikvA	1	0.8884	92.7	0.954	Contact Map
4j05A	3	0.8326	90.8	0.956	Contact Map
2jlnA	1	0.8412	88.1	0.959	Contact Map
3o7qA	1	0.4163	87.3	0.959	Contact Map
3wdoA	1	0.8391	86.4	0.96	Contact Map
4m64A	1	0.8391	83.9	0.961	Contact Map
4w6vA	1	0.8584	83	0.961	Contact Map
4tphA	2	0.8262	80.6	0.962	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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