BEPA - ECOLI - GREMLIN Contacts

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BEPA - Beta-barrel assembly-enhancing protease

UniProt:	P66948	Sequences: MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLTWVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14199
Length:	487 (425)
Sequences:	1184 (917)
Seq/√Len:	44.5

ECOLI - BEPA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
358_K	361_E	4.599	1.00
129_Q	224_T	4.222	1.00
324_K	327_E	4.078	1.00
116_L	134_M	3.741	1.00
125_D	228_K	3.469	1.00
391_Q	394_E	3.451	1.00
382_L	386_Y	3.414	1.00
80_G	96_F	3.184	1.00
434_A	441_G	2.993	1.00
432_A	435_E	2.889	1.00
434_A	446_A	2.883	1.00
333_Q	349_A	2.864	1.00
446_A	453_A	2.859	1.00
194_I	197_T	2.838	1.00
274_F	278_K	2.796	1.00
367_K	394_E	2.758	1.00
441_G	446_A	2.653	1.00
435_E	453_A	2.600	1.00
353_D	361_E	2.532	1.00
363_I	382_L	2.515	1.00
132_S	221_A	2.499	1.00
425_N	428_Q	2.480	1.00
280_R	284_M	2.454	1.00
449_L	452_S	2.426	1.00
293_T	297_L	2.411	1.00
319_A	327_E	2.357	1.00
434_A	453_A	2.341	1.00
386_Y	394_E	2.307	1.00
354_L	385_A	2.298	1.00
449_L	453_A	2.272	1.00
432_A	446_A	2.213	1.00
33_L	36_M	2.202	1.00
34_P	37_G	2.189	1.00
129_Q	228_K	2.178	1.00
430_L	449_L	2.150	1.00
429_E	436_G	2.123	1.00
436_G	449_L	2.107	1.00
430_L	436_G	2.088	0.99
443_L	446_A	2.027	0.99
434_A	438_A	2.012	0.99
433_R	436_G	2.008	0.99
436_G	453_A	2.001	0.99
124_S	130_L	1.959	0.99
432_A	436_G	1.941	0.99
430_L	453_A	1.916	0.99
274_F	277_A	1.884	0.99
435_E	438_A	1.884	0.99
297_L	300_W	1.880	0.99
441_G	453_A	1.855	0.99
223_P	256_A	1.848	0.99
297_L	301_A	1.834	0.99
429_E	433_R	1.818	0.99
367_K	382_L	1.813	0.99
432_A	438_A	1.811	0.98
49_E	144_R	1.794	0.98
309_R	345_Y	1.764	0.98
436_G	446_A	1.751	0.98
312_Q	331_T	1.738	0.98
278_K	281_T	1.719	0.98
430_L	434_A	1.714	0.98
101_N	117_H	1.684	0.98
103_E	117_H	1.684	0.98
446_A	449_L	1.673	0.97
438_A	446_A	1.658	0.97
191_Q	195_S	1.655	0.97
432_A	441_G	1.652	0.97
84_V	114_V	1.629	0.97
339_E	342_N	1.627	0.97
430_L	437_Y	1.615	0.97
366_L	381_N	1.615	0.97
353_D	365_R	1.611	0.97
430_L	446_A	1.609	0.97
277_A	281_T	1.601	0.97
438_A	441_G	1.582	0.96
83_L	138_I	1.582	0.96
239_P	244_L	1.580	0.96
276_L	280_R	1.574	0.96
86_H	215_S	1.566	0.96
313_Y	317_L	1.561	0.96
294_S	297_L	1.552	0.96
349_A	365_R	1.548	0.96
281_T	284_M	1.536	0.96
121_F	130_L	1.533	0.96
202_Q	251_S	1.517	0.95
427_D	436_G	1.512	0.95
436_G	441_G	1.511	0.95
120_L	133_V	1.508	0.95
438_A	453_A	1.508	0.95
435_E	446_A	1.500	0.95
435_E	441_G	1.494	0.95
396_A	420_E	1.491	0.95
427_D	434_A	1.486	0.95
227_E	257_R	1.485	0.95
441_G	449_L	1.482	0.95
79_L	217_F	1.481	0.95
434_A	449_L	1.481	0.95
296_L	300_W	1.476	0.95
443_L	453_A	1.463	0.94
396_A	416_L	1.457	0.94
220_Q	261_N	1.457	0.94
56_Y	109_F	1.454	0.94
241_E	251_S	1.454	0.94
312_Q	338_A	1.452	0.94
399_L	416_L	1.446	0.94
280_R	283_G	1.432	0.94
363_I	385_A	1.429	0.94
413_W	432_A	1.424	0.94
329_R	349_A	1.424	0.94
316_A	332_L	1.422	0.94
433_R	441_G	1.413	0.93
274_F	281_T	1.399	0.93
409_D	413_W	1.397	0.93
131_A	217_F	1.395	0.93
432_A	443_L	1.388	0.93
277_A	280_R	1.379	0.92
208_G	215_S	1.377	0.92
290_N	293_T	1.374	0.92
80_G	134_M	1.366	0.92
432_A	453_A	1.366	0.92
163_G	185_T	1.359	0.92
339_E	345_Y	1.355	0.92
124_S	274_F	1.349	0.92
429_E	438_A	1.343	0.91
278_K	282_L	1.341	0.91
319_A	324_K	1.333	0.91
436_G	443_L	1.332	0.91
80_G	94_F	1.331	0.91
278_K	284_M	1.326	0.91
329_R	333_Q	1.318	0.91
431_A	435_E	1.313	0.90
426_R	432_A	1.304	0.90
435_E	447_I	1.301	0.90
370_R	378_L	1.289	0.90
274_F	279_A	1.286	0.90
353_D	358_K	1.284	0.89
363_I	389_G	1.271	0.89
72_L	277_A	1.257	0.88
434_A	437_Y	1.257	0.88
427_D	435_E	1.253	0.88
427_D	432_A	1.249	0.88
197_T	202_Q	1.248	0.88
438_A	443_L	1.247	0.88
33_L	37_G	1.245	0.88
442_R	445_Q	1.235	0.88
181_A	184_G	1.235	0.88
50_M	54_D	1.233	0.87
351_D	355_G	1.231	0.87
434_A	443_L	1.230	0.87
199_Q	202_Q	1.229	0.87
432_A	449_L	1.228	0.87
451_S	455_S	1.227	0.87
186_L	190_R	1.223	0.87
290_N	297_L	1.217	0.87
284_M	288_G	1.212	0.87
293_T	296_L	1.211	0.86
437_Y	453_A	1.210	0.86
310_A	314_G	1.209	0.86
128_S	270_S	1.208	0.86
436_G	440_A	1.199	0.86
108_A	112_G	1.199	0.86
208_G	216_G	1.197	0.86
430_L	452_S	1.196	0.86
226_L	253_L	1.194	0.86
446_A	450_L	1.192	0.86
336_L	346_L	1.190	0.86
329_R	353_D	1.187	0.85
94_F	142_T	1.175	0.85
396_A	419_A	1.171	0.85
429_E	437_Y	1.171	0.85
444_D	448_S	1.159	0.84
451_S	454_S	1.159	0.84
125_D	129_Q	1.158	0.84
312_Q	334_P	1.152	0.84
209_I	256_A	1.147	0.83
329_R	356_Q	1.142	0.83
75_Y	127_E	1.139	0.83
429_E	449_L	1.138	0.83
429_E	435_E	1.130	0.82
447_I	450_L	1.130	0.82
349_A	353_D	1.128	0.82
351_D	381_N	1.127	0.82
385_A	389_G	1.126	0.82
433_R	453_A	1.120	0.82
279_A	282_L	1.116	0.82
33_L	38_T	1.115	0.82
384_N	388_Q	1.114	0.81
274_F	284_M	1.112	0.81
437_Y	446_A	1.110	0.81
80_G	138_I	1.105	0.81
448_S	453_A	1.104	0.81
293_T	301_A	1.102	0.81
444_D	453_A	1.102	0.81
429_E	432_A	1.098	0.81
437_Y	449_L	1.087	0.80
126_N	129_Q	1.081	0.79
434_A	450_L	1.072	0.79
104_I	229_L	1.072	0.79
173_A	176_Q	1.069	0.79
165_L	168_I	1.066	0.79
429_E	453_A	1.063	0.78
75_Y	79_L	1.063	0.78
449_L	454_S	1.058	0.78
179_M	183_T	1.056	0.78
443_L	447_I	1.056	0.78
149_A	196_F	1.049	0.77
447_I	453_A	1.038	0.77
142_T	211_V	1.038	0.77
118_S	281_T	1.036	0.77
443_L	449_L	1.033	0.76
107_F	115_V	1.032	0.76
167_S	182_L	1.025	0.76
290_N	296_L	1.024	0.76
235_Y	240_P	1.023	0.76
437_Y	441_G	1.022	0.76
448_S	452_S	1.022	0.76
435_E	443_L	1.019	0.75
438_A	449_L	1.013	0.75
279_A	284_M	1.010	0.75
429_E	447_I	1.007	0.74
429_E	452_S	1.004	0.74
132_S	222_M	0.997	0.74
277_A	283_G	0.989	0.73
435_E	449_L	0.987	0.73
277_A	284_M	0.984	0.73
166_G	171_A	0.982	0.73
167_S	170_L	0.982	0.73
429_E	443_L	0.978	0.72
427_D	453_A	0.975	0.72
360_N	391_Q	0.973	0.72
143_Q	203_E	0.965	0.71
72_L	98_L	0.956	0.70
208_G	222_M	0.954	0.70
97_F	113_N	0.954	0.70
368_N	371_D	0.951	0.70
393_Q	423_L	0.949	0.70
331_T	334_P	0.949	0.70
206_R	255_D	0.947	0.70
191_Q	194_I	0.947	0.70
333_Q	337_A	0.942	0.69
222_M	260_A	0.942	0.69
164_A	167_S	0.936	0.69
276_L	279_A	0.934	0.69
76_I	96_F	0.931	0.68
326_D	356_Q	0.931	0.68
96_F	138_I	0.931	0.68
292_L	296_L	0.931	0.68
331_T	335_L	0.930	0.68
49_E	53_G	0.927	0.68
274_F	280_R	0.926	0.68
433_R	437_Y	0.924	0.68
367_K	371_D	0.920	0.68
69_D	119_A	0.919	0.67
79_L	131_A	0.915	0.67
248_L	253_L	0.915	0.67
359_A	363_I	0.915	0.67
235_Y	239_P	0.914	0.67
394_E	397_N	0.911	0.67
427_D	430_L	0.909	0.67
428_Q	436_G	0.909	0.67
382_L	398_I	0.907	0.66
272_E	276_L	0.907	0.66
280_R	288_G	0.904	0.66
427_D	441_G	0.903	0.66
444_D	452_S	0.903	0.66
380_L	399_L	0.893	0.65
452_S	455_S	0.892	0.65
258_N	262_Q	0.889	0.65
387_L	419_A	0.884	0.64
310_A	313_Y	0.884	0.64
443_L	450_L	0.883	0.64
57_V	113_N	0.883	0.64
190_R	193_M	0.873	0.63
443_L	448_S	0.873	0.63
415_L	418_Q	0.872	0.63
427_D	446_A	0.872	0.63
212_L	222_M	0.870	0.63
430_L	433_R	0.870	0.63
278_K	285_Y	0.870	0.63
432_A	437_Y	0.869	0.63
108_A	115_V	0.869	0.63
104_I	225_F	0.866	0.63
298_D	301_A	0.862	0.62
426_R	436_G	0.862	0.62
421_A	453_A	0.862	0.62
435_E	439_L	0.860	0.62
167_S	178_G	0.859	0.62
124_S	196_F	0.854	0.62
360_N	389_G	0.853	0.62
444_D	449_L	0.852	0.62
315_R	319_A	0.851	0.61
296_L	299_E	0.851	0.61
386_Y	398_I	0.850	0.61
396_A	423_L	0.849	0.61
427_D	449_L	0.848	0.61
334_P	337_A	0.848	0.61
430_L	438_A	0.846	0.61
223_P	255_D	0.843	0.61
406_N	409_D	0.841	0.61
437_Y	452_S	0.836	0.60
368_N	372_L	0.836	0.60
403_T	413_W	0.835	0.60
293_T	300_W	0.835	0.60
430_L	441_G	0.834	0.60
431_A	434_A	0.833	0.60
295_D	299_E	0.828	0.59
320_M	348_L	0.826	0.59
121_F	281_T	0.825	0.59
143_Q	148_R	0.823	0.59
430_L	443_L	0.822	0.59
387_L	392_P	0.821	0.59
439_L	447_I	0.820	0.59
143_Q	207_I	0.818	0.58
197_T	200_N	0.818	0.58
80_G	127_E	0.817	0.58
450_L	453_A	0.816	0.58
57_V	61_R	0.814	0.58
447_I	452_S	0.812	0.58
136_H	246_H	0.809	0.58
278_K	283_G	0.803	0.57
432_A	447_I	0.803	0.57
429_E	441_G	0.802	0.57
290_N	294_S	0.800	0.57
369_A	378_L	0.799	0.57
159_L	163_G	0.797	0.56
440_A	446_A	0.797	0.56
257_R	261_N	0.795	0.56
359_A	385_A	0.790	0.56
110_F	203_E	0.788	0.56
430_L	435_E	0.786	0.55
144_R	203_E	0.786	0.55
439_L	452_S	0.784	0.55
141_V	146_L	0.784	0.55
186_L	189_T	0.784	0.55
274_F	283_G	0.782	0.55
139_S	211_V	0.781	0.55
429_E	439_L	0.780	0.55
445_Q	448_S	0.778	0.55
426_R	429_E	0.775	0.54
413_W	416_L	0.772	0.54
113_N	146_L	0.771	0.54
75_Y	112_G	0.766	0.53
163_G	171_A	0.764	0.53
225_F	229_L	0.764	0.53
143_Q	259_R	0.764	0.53
221_A	226_L	0.763	0.53
336_L	349_A	0.761	0.53
124_S	164_A	0.761	0.53
379_Q	398_I	0.761	0.53
131_A	215_S	0.761	0.53
57_V	97_F	0.760	0.53
442_R	446_A	0.759	0.53
441_G	447_I	0.757	0.53
185_T	221_A	0.754	0.52
433_R	446_A	0.754	0.52
149_A	200_N	0.751	0.52
319_A	331_T	0.750	0.52
80_G	114_V	0.749	0.52
158_P	166_G	0.747	0.52
139_S	142_T	0.747	0.52
42_S	45_S	0.746	0.51
354_L	388_Q	0.746	0.51
399_L	403_T	0.746	0.51
400_N	420_E	0.742	0.51
109_F	146_L	0.741	0.51
421_A	433_R	0.740	0.51
431_A	441_G	0.740	0.51
316_A	424_N	0.740	0.51
326_D	358_K	0.739	0.51
89_S	94_F	0.733	0.50
210_Q	214_R	0.733	0.50
187_A	191_Q	0.732	0.50
428_Q	432_A	0.728	0.50
63_S	66_L	0.728	0.50
276_L	281_T	0.727	0.50
441_G	444_D	0.726	0.50
433_R	440_A	0.725	0.49
303_G	308_Q	0.725	0.49
433_R	449_L	0.725	0.49
436_G	447_I	0.722	0.49
309_R	339_E	0.721	0.49
131_A	208_G	0.720	0.49
71_L	280_R	0.720	0.49
137_E	201_E	0.714	0.48
444_D	451_S	0.713	0.48
191_Q	243_L	0.710	0.48
52_M	55_Y	0.709	0.48
206_R	259_R	0.708	0.48
111_G	147_A	0.708	0.48
124_S	225_F	0.708	0.48
120_L	253_L	0.708	0.48
432_A	440_A	0.707	0.48
413_W	435_E	0.705	0.48
416_L	419_A	0.705	0.48
435_E	440_A	0.705	0.48
343_A	347_D	0.704	0.47
307_Q	311_A	0.704	0.47
400_N	416_L	0.703	0.47
105_N	247_P	0.702	0.47
49_E	147_A	0.702	0.47
121_F	277_A	0.700	0.47
238_R	244_L	0.699	0.47
82_R	268_V	0.699	0.47
180_A	184_G	0.697	0.47
283_G	287_S	0.689	0.46
296_L	301_A	0.686	0.46
421_A	426_R	0.685	0.46
303_G	306_R	0.684	0.45
427_D	438_A	0.683	0.45
317_L	348_L	0.677	0.45
48_Q	51_Q	0.676	0.45
350_T	366_L	0.674	0.45
433_R	443_L	0.673	0.44
181_A	324_K	0.669	0.44
112_G	217_F	0.669	0.44
447_I	454_S	0.667	0.44
194_I	242_I	0.666	0.44
430_L	448_S	0.664	0.44
221_A	242_I	0.661	0.43
439_L	450_L	0.658	0.43
175_P	178_G	0.658	0.43
435_E	444_D	0.658	0.43
128_S	221_A	0.657	0.43
80_G	97_F	0.655	0.43
431_A	438_A	0.655	0.43
74_Q	78_S	0.654	0.43
134_M	298_D	0.651	0.42
115_V	244_L	0.650	0.42
418_Q	422_A	0.647	0.42
84_V	94_F	0.646	0.42
330_K	334_P	0.645	0.42
255_D	259_R	0.643	0.42
275_Y	278_K	0.643	0.42
140_H	201_E	0.643	0.42
137_E	140_H	0.643	0.42
431_A	436_G	0.643	0.42
109_F	147_A	0.642	0.42
136_H	252_R	0.641	0.41
246_H	252_R	0.641	0.41
130_L	150_M	0.641	0.41
308_Q	312_Q	0.639	0.41
443_L	451_S	0.639	0.41
132_S	223_P	0.638	0.41
332_L	348_L	0.637	0.41
315_R	331_T	0.636	0.41
201_E	246_H	0.635	0.41
136_H	201_E	0.635	0.41
137_E	246_H	0.635	0.41
139_S	174_S	0.632	0.41
225_F	249_P	0.630	0.40
167_S	171_A	0.630	0.40
420_E	425_N	0.630	0.40
308_Q	311_A	0.628	0.40
60_L	141_V	0.628	0.40
440_A	444_D	0.626	0.40
280_R	285_Y	0.625	0.40
392_P	422_A	0.624	0.40
291_Q	298_D	0.622	0.40
221_A	248_L	0.621	0.40
432_A	439_L	0.621	0.40
427_D	437_Y	0.620	0.39
313_Y	316_A	0.617	0.39
440_A	445_Q	0.617	0.39
196_F	245_T	0.616	0.39
137_E	204_A	0.614	0.39
201_E	204_A	0.614	0.39
335_L	345_Y	0.613	0.39
426_R	435_E	0.612	0.39
444_D	447_I	0.608	0.38
209_I	258_N	0.608	0.38
213_Q	263_M	0.607	0.38
343_A	369_A	0.606	0.38
347_D	351_D	0.602	0.38
421_A	437_Y	0.602	0.38
164_A	186_L	0.601	0.38
420_E	428_Q	0.601	0.38
38_T	41_G	0.600	0.38
383_A	399_L	0.599	0.38
358_K	393_Q	0.599	0.38
440_A	448_S	0.598	0.37
72_L	281_T	0.597	0.37
187_A	243_L	0.597	0.37
96_F	114_V	0.597	0.37
382_L	394_E	0.596	0.37
415_L	419_A	0.595	0.37
434_A	440_A	0.594	0.37
194_I	245_T	0.594	0.37
433_R	454_S	0.592	0.37
361_E	394_E	0.592	0.37
32_T	39_S	0.592	0.37
281_T	285_Y	0.592	0.37
403_T	412_G	0.589	0.37
125_D	278_K	0.589	0.37
84_V	138_I	0.589	0.37
427_D	433_R	0.589	0.37
49_E	75_Y	0.586	0.36
215_S	219_P	0.586	0.36
432_A	445_Q	0.584	0.36
441_G	452_S	0.583	0.36
430_L	454_S	0.582	0.36
309_R	338_A	0.579	0.36
138_I	225_F	0.576	0.35
75_Y	243_L	0.575	0.35
208_G	213_Q	0.575	0.35
107_F	242_I	0.575	0.35
160_T	163_G	0.574	0.35
139_S	223_P	0.574	0.35
427_D	431_A	0.573	0.35
167_S	186_L	0.573	0.35
358_K	367_K	0.573	0.35
437_Y	442_R	0.572	0.35
313_Y	335_L	0.569	0.35
230_L	249_P	0.568	0.35
433_R	447_I	0.567	0.35
236_S	240_P	0.567	0.35
236_S	239_P	0.567	0.35
314_G	318_Q	0.566	0.35
428_Q	437_Y	0.566	0.35
276_L	282_L	0.566	0.35
364_N	392_P	0.564	0.34
421_A	436_G	0.564	0.34
140_H	246_H	0.564	0.34
136_H	140_H	0.564	0.34
397_N	401_R	0.563	0.34
198_Q	251_S	0.562	0.34
228_K	278_K	0.562	0.34
82_R	217_F	0.562	0.34
54_D	113_N	0.562	0.34
115_V	226_L	0.561	0.34
366_L	382_L	0.561	0.34
200_N	203_E	0.561	0.34
448_S	455_S	0.560	0.34
111_G	208_G	0.559	0.34
393_Q	397_N	0.559	0.34
67_I	118_S	0.558	0.34
157_A	160_T	0.557	0.34
116_L	253_L	0.557	0.34
268_V	271_S	0.557	0.34
440_A	449_L	0.556	0.34
400_N	404_F	0.555	0.34
437_Y	440_A	0.554	0.34
438_A	447_I	0.554	0.34
156_S	159_L	0.553	0.33
448_S	451_S	0.552	0.33
53_G	61_R	0.552	0.33
82_R	127_E	0.552	0.33
426_R	430_L	0.551	0.33
428_Q	433_R	0.551	0.33
357_N	391_Q	0.550	0.33
45_S	49_E	0.550	0.33
131_A	212_L	0.549	0.33
140_H	204_A	0.549	0.33
95_H	113_N	0.549	0.33
445_Q	449_L	0.548	0.33
244_L	249_P	0.547	0.33
221_A	260_A	0.547	0.33
199_Q	321_E	0.547	0.33
80_G	141_V	0.546	0.33
440_A	452_S	0.546	0.33
379_Q	389_G	0.544	0.33
127_E	274_F	0.544	0.33
428_Q	431_A	0.543	0.33
124_S	212_L	0.542	0.33
414_D	419_A	0.542	0.33
440_A	447_I	0.541	0.32
148_R	203_E	0.541	0.32
185_T	189_T	0.541	0.32
149_A	153_Q	0.540	0.32
52_M	63_S	0.539	0.32
83_L	211_V	0.539	0.32
114_V	232_Q	0.538	0.32
447_I	451_S	0.537	0.32
437_Y	443_L	0.536	0.32
128_S	268_V	0.536	0.32
180_A	183_T	0.536	0.32
79_L	130_L	0.535	0.32
51_Q	59_Q	0.535	0.32
112_G	127_E	0.534	0.32
240_P	244_L	0.533	0.32
76_I	98_L	0.532	0.32
413_W	419_A	0.532	0.32
96_F	191_Q	0.530	0.32
226_L	256_A	0.529	0.31
204_A	246_H	0.529	0.31
136_H	204_A	0.529	0.31
96_F	129_Q	0.528	0.31
201_E	205_D	0.527	0.31
137_E	205_D	0.527	0.31
79_L	215_S	0.527	0.31
255_D	258_N	0.527	0.31
320_M	388_Q	0.527	0.31
205_D	252_R	0.527	0.31
56_Y	166_G	0.527	0.31
120_L	197_T	0.526	0.31
431_A	439_L	0.525	0.31
113_N	226_L	0.525	0.31
238_R	250_E	0.524	0.31
326_D	371_D	0.524	0.31
154_Q	177_A	0.523	0.31
43_T	48_Q	0.523	0.31
344_W	349_A	0.522	0.31
276_L	283_G	0.522	0.31
130_L	146_L	0.521	0.31
61_R	218_D	0.521	0.31
104_I	123_Y	0.521	0.31
429_E	434_A	0.521	0.31
433_R	452_S	0.519	0.31
349_A	352_I	0.519	0.31
426_R	443_L	0.519	0.31
348_L	351_D	0.518	0.31
384_N	387_L	0.518	0.31
41_G	223_P	0.517	0.30
58_R	61_R	0.517	0.30
437_Y	445_Q	0.516	0.30
139_S	207_I	0.514	0.30
360_N	394_E	0.514	0.30
221_A	244_L	0.513	0.30
111_G	248_L	0.513	0.30
341_G	371_D	0.512	0.30
426_R	449_L	0.510	0.30
49_E	187_A	0.509	0.30
388_Q	415_L	0.509	0.30
75_Y	130_L	0.508	0.30
109_F	113_N	0.508	0.30
213_Q	219_P	0.508	0.30
442_R	454_S	0.508	0.30
426_R	437_Y	0.507	0.30
197_T	244_L	0.507	0.30
70_P	164_A	0.507	0.30
418_Q	421_A	0.507	0.30
416_L	420_E	0.506	0.30
423_L	449_L	0.505	0.29
189_T	229_L	0.505	0.29
158_P	163_G	0.503	0.29
70_P	375_N	0.503	0.29
34_P	61_R	0.502	0.29
344_W	347_D	0.502	0.29
325_Y	333_Q	0.501	0.29
58_R	62_G	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3c37A	1	0.4559	100	0.616	Contact Map
4aw6A	2	0.5051	100	0.746	Contact Map
4il3A	1	0.499	100	0.751	Contact Map
3dssA	1	0.4702	99.8	0.827	Contact Map
4l9pA	1	0.4908	99.8	0.828	Contact Map
3q7aA	1	0.4784	99.8	0.829	Contact Map
1dceA	1	0.4928	99.8	0.832	Contact Map
3draA	1	0.4969	99.8	0.835	Contact Map
4gywA	2	0.4333	99.8	0.835	Contact Map
2vsyA	1	0.3676	99.8	0.838	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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