GREMLIN Database
YGEY - Uncharacterized protein YgeY
UniProt: P65807 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13055
Length: 403 (358)
Sequences: 29435 (20847)
Seq/√Len: 1101.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
68_Y141_L3.4281.00
193_D257_S3.1491.00
46_K50_E2.8961.00
27_D44_R2.8261.00
193_D259_A2.8251.00
199_C207_G2.7291.00
106_L379_K2.7101.00
75_L139_T2.4971.00
280_R284_A2.4631.00
194_V217_I2.4621.00
276_L280_R2.4471.00
195_Q257_S2.4391.00
191_R259_A2.4331.00
334_G394_A2.4121.00
48_E51_K2.3881.00
330_N398_S2.3871.00
128_I393_A2.3481.00
334_G398_S2.3451.00
195_Q306_V2.2971.00
52_V127_K2.2681.00
214_M244_I2.2471.00
49_M67_G2.2211.00
214_M258_C2.2151.00
44_R48_E2.2011.00
191_R261_S2.1691.00
213_K303_T2.1651.00
68_Y139_T2.1621.00
75_L141_L2.1571.00
277_D281_A2.1391.00
245_F259_A2.1271.00
128_I132_L2.0391.00
214_M260_V2.0361.00
77_A167_P2.0241.00
195_Q304_G1.9851.00
216_P219_G1.9741.00
243_E261_S1.9701.00
20_D127_K1.9621.00
329_V333_E1.9451.00
193_D308_P1.9391.00
31_I44_R1.9091.00
157_Q161_E1.8991.00
215_G218_L1.8941.00
39_K43_H1.8841.00
95_F103_T1.8141.00
48_E52_V1.7921.00
94_D377_N1.7801.00
328_L395_I1.7671.00
47_E51_K1.7521.00
191_R308_P1.7471.00
72_G137_E1.7341.00
217_I283_P1.7301.00
40_R43_H1.7131.00
193_D306_V1.7121.00
43_H47_E1.7061.00
44_R47_E1.6741.00
210_A258_C1.6591.00
197_V208_D1.6441.00
21_M389_A1.6381.00
24_F48_E1.6381.00
105_E383_S1.6331.00
26_R30_A1.6271.00
394_A397_L1.6101.00
208_D213_K1.6101.00
278_E281_A1.6091.00
127_K131_D1.5971.00
215_G219_G1.5901.00
273_E277_D1.5891.00
27_D40_R1.5871.00
158_Y161_E1.5811.00
46_K65_V1.5761.00
54_F69_I1.5761.00
246_F258_C1.5721.00
284_A290_A1.5681.00
23_R27_D1.5611.00
212_F222_Q1.5581.00
333_E339_A1.5541.00
27_D30_A1.5471.00
198_S256_D1.5401.00
203_A206_R1.5201.00
121_S388_C1.5111.00
42_V82_I1.4991.00
220_E282_L1.4841.00
21_M124_Y1.4761.00
77_A143_T1.4741.00
326_K329_V1.4701.00
39_K63_G1.4681.00
19_A23_R1.4641.00
271_T274_G1.4621.00
274_G278_E1.4591.00
74_R168_E1.4541.00
237_G275_A1.4531.00
45_I82_I1.4521.00
47_E50_E1.4451.00
27_D31_I1.4381.00
48_E127_K1.4371.00
327_A398_S1.3951.00
220_E287_K1.3871.00
194_V214_M1.3831.00
394_A398_S1.3701.00
77_A170_V1.3501.00
130_K133_G1.3481.00
30_A102_E1.3481.00
69_I130_K1.3481.00
387_T390_A1.3461.00
56_K59_I1.3451.00
190_I262_I1.3391.00
277_D280_R1.3191.00
22_T26_R1.3141.00
46_K58_E1.3121.00
117_G385_L1.3111.00
191_R310_E1.3081.00
78_M122_M1.3001.00
211_I246_F1.2921.00
23_R26_R1.2901.00
192_I260_V1.2881.00
331_A398_S1.2851.00
329_V342_V1.2831.00
230_Y278_E1.2771.00
80_A115_Q1.2731.00
117_G380_T1.2631.00
235_G268_W1.2561.00
102_E382_K1.2481.00
359_G362_V1.2411.00
332_Y391_M1.2391.00
386_V390_A1.2381.00
33_S41_V1.2261.00
331_A394_A1.2221.00
35_S150_D1.2201.00
78_M396_P1.2171.00
24_F44_R1.2141.00
132_L393_A1.2121.00
24_F124_Y1.2091.00
20_D23_R1.2091.00
276_L309_T1.2061.00
43_H46_K1.2051.00
194_V213_K1.2031.00
383_S387_T1.1941.00
46_K59_I1.1901.00
326_K330_N1.1861.00
211_I244_I1.1801.00
327_A331_A1.1751.00
330_N334_G1.1621.00
281_A284_A1.1541.00
21_M120_A1.1431.00
355_M360_I1.1381.00
132_L397_L1.1291.00
274_G277_D1.1281.00
185_R188_M1.1281.00
28_M41_V1.1261.00
126_G142_V1.1201.00
158_Y162_Q1.1161.00
276_L311_C1.1151.00
29_V109_G1.1141.00
224_L278_E1.1081.00
26_R102_E1.1061.00
268_W271_T1.1041.00
220_E223_E1.0931.00
27_D48_E1.0931.00
381_W384_H1.0841.00
106_L381_W1.0781.00
74_R138_Y1.0771.00
40_R44_R1.0741.00
219_G223_E1.0731.00
26_R100_G1.0711.00
71_H137_E1.0671.00
173_T392_Y1.0671.00
75_L168_E1.0651.00
70_G73_P1.0611.00
287_K290_A1.0591.00
322_H326_K1.0561.00
24_F127_K1.0521.00
45_I119_M1.0501.00
26_R382_K1.0421.00
31_I40_R1.0391.00
281_A287_K1.0391.00
218_L260_V1.0381.00
177_D373_A1.0351.00
95_F101_M1.0281.00
93_W96_D1.0241.00
330_N333_E1.0221.00
245_F249_P1.0141.00
117_G175_P1.0101.00
54_F67_G1.0101.00
32_P37_D1.0081.00
69_I136_D1.0051.00
29_V112_T1.0031.00
42_V65_V1.0001.00
190_I276_L0.9991.00
212_F218_L0.9961.00
50_E56_K0.9961.00
241_V262_I0.9961.00
180_V183_G0.9911.00
105_E381_W0.9851.00
95_F98_Y0.9841.00
278_E282_L0.9821.00
124_Y127_K0.9781.00
284_A289_N0.9771.00
49_M123_V0.9741.00
122_M142_V0.9741.00
289_N305_L0.9731.00
64_N146_V0.9691.00
214_M218_L0.9641.00
393_A397_L0.9631.00
328_L363_I0.9611.00
20_D24_F0.9591.00
216_P220_E0.9581.00
82_I144_G0.9581.00
28_M44_R0.9541.00
216_P223_E0.9521.00
218_L241_V0.9481.00
250_S253_A0.9451.00
389_A393_A0.9431.00
42_V46_K0.9421.00
169_F324_T0.9401.00
125_A393_A0.9391.00
331_A334_G0.9381.00
321_D324_T0.9371.00
181_Y184_Q0.9361.00
192_I283_P0.9361.00
380_T385_L0.9331.00
21_M385_L0.9301.00
390_A394_A0.9291.00
128_I390_A0.9251.00
327_A330_N0.9251.00
20_D48_E0.9251.00
57_V68_Y0.9231.00
178_C183_G0.9211.00
36_C147_Q0.9191.00
280_R307_Y0.9191.00
80_A119_M0.9131.00
360_I366_G0.9121.00
195_Q256_D0.9101.00
55_D68_Y0.9091.00
184_Q188_M0.9061.00
191_R251_R0.9051.00
70_G139_T0.9011.00
251_R261_S0.8961.00
37_D40_R0.8951.00
384_H387_T0.8921.00
57_V60_D0.8901.00
82_I119_M0.8881.00
283_P305_L0.8851.00
54_F126_G0.8831.00
125_A392_Y0.8771.00
221_L279_I0.8761.00
48_E123_V0.8731.00
327_A395_I0.8731.00
52_V130_K0.8701.00
88_G104_D0.8681.00
103_T106_L0.8651.00
359_G366_G0.8641.00
71_H135_E0.8631.00
333_E338_K0.8601.00
192_I217_I0.8581.00
323_F327_A0.8571.00
212_F215_G0.8551.00
282_L287_K0.8541.00
216_P222_Q0.8521.00
211_I258_C0.8511.00
218_L244_I0.8501.00
362_V365_F0.8491.00
323_F326_K0.8491.00
69_I126_G0.8471.00
179_Q183_G0.8431.00
27_D47_E0.8401.00
372_E375_A0.8391.00
180_V184_Q0.8381.00
269_G273_E0.8351.00
355_M358_H0.8341.00
273_E276_L0.8321.00
46_K56_K0.8321.00
325_V329_V0.8301.00
141_L167_P0.8271.00
103_T108_G0.8231.00
266_L272_W0.8191.00
87_I98_Y0.8181.00
281_A290_A0.8171.00
41_V82_I0.8101.00
244_I258_C0.8101.00
371_P377_N0.8101.00
282_L288_A0.8071.00
102_E105_E0.8061.00
156_W160_I0.8051.00
91_K95_F0.8041.00
383_S386_V0.8021.00
132_L135_E0.8021.00
208_D303_T0.8011.00
188_M272_W0.8011.00
76_V169_F0.7991.00
101_M104_D0.7971.00
52_V123_V0.7961.00
181_Y185_R0.7951.00
178_C182_R0.7941.00
336_F394_A0.7931.00
171_V395_I0.7911.00
115_Q118_G0.7891.00
50_E58_E0.7891.00
66_L141_L0.7851.00
183_G344_K0.7851.00
43_H58_E0.7821.00
128_I131_D0.7821.00
30_A100_G0.7801.00
270_E274_G0.7801.00
212_F223_E0.7791.00
94_D103_T0.7791.00
78_M125_A0.7761.00
54_F130_K0.7761.00
24_F120_A0.7751.00
46_K57_V0.7661.00
92_N95_F0.7661.00
33_S116_E0.7631.00
25_L107_I0.7621.00
126_G130_K0.7611.00
121_S389_A0.7601.00
97_P100_G0.7591.00
51_K127_K0.7571.00
121_S392_Y0.7571.00
219_G222_Q0.7561.00
362_V366_G0.7561.00
24_F27_D0.7541.00
125_A389_A0.7511.00
95_F100_G0.7491.00
93_W97_P0.7481.00
128_I389_A0.7461.00
328_L391_M0.7441.00
154_L158_Y0.7391.00
22_T102_E0.7361.00
264_R275_A0.7351.00
385_L389_A0.7351.00
241_V260_V0.7351.00
221_L239_L0.7321.00
213_K305_L0.7291.00
220_E288_A0.7271.00
313_F316_W0.7251.00
332_Y336_F0.7251.00
127_K130_K0.7231.00
100_G107_I0.7231.00
141_L166_R0.7221.00
124_Y389_A0.7211.00
361_P366_G0.7211.00
121_S125_A0.7181.00
92_N96_D0.7161.00
75_L138_Y0.7161.00
170_V360_I0.7161.00
188_M276_L0.7141.00
272_W314_P0.7111.00
194_V260_V0.7091.00
272_W276_L0.7091.00
336_F391_M0.7091.00
26_R29_V0.7071.00
94_D97_P0.7061.00
34_E86_G0.7051.00
331_A391_M0.7021.00
184_Q187_R0.7011.00
360_I365_F0.6961.00
178_C185_R0.6931.00
122_M173_T0.6931.00
65_V144_G0.6911.00
217_I260_V0.6901.00
360_I363_I0.6901.00
45_I123_V0.6881.00
45_I144_G0.6871.00
197_V375_A0.6871.00
189_E263_D0.6851.00
84_T98_Y0.6851.00
42_V63_G0.6831.00
76_V396_P0.6811.00
245_F248_S0.6791.00
311_C314_P0.6791.00
239_L264_R0.6781.00
368_G380_T0.6761.00
24_F28_M0.6761.00
225_S239_L0.6751.00
180_V185_R0.6731.00
54_F57_V0.6721.00
331_A395_I0.6701.00
351_G362_V0.6681.00
73_P139_T0.6681.00
45_I65_V0.6681.00
199_C254_V0.6641.00
36_C150_D0.6621.00
50_E55_D0.6621.00
34_E98_Y0.6611.00
69_I142_V0.6601.00
119_M144_G0.6591.00
273_E311_C0.6571.00
34_E37_D0.6571.00
372_E377_N0.6551.00
174_E177_D0.6531.00
190_I279_I0.6531.00
390_A393_A0.6511.00
20_D124_Y0.6501.00
56_K67_G0.6491.00
205_E232_E0.6491.00
186_G266_L0.6441.00
22_T382_K0.6421.00
280_R309_T0.6421.00
171_V324_T0.6421.00
28_M119_M0.6411.00
143_T159_I0.6371.00
391_M395_I0.6361.00
209_N255_A0.6321.00
189_E251_R0.6311.00
371_P375_A0.6281.00
172_S351_G0.6251.00
363_I366_G0.6241.00
58_E164_G0.6221.00
72_G139_T0.6221.00
57_V164_G0.6211.00
26_R107_I0.6201.00
309_T312_Y0.6201.00
182_R185_R0.6191.00
321_D326_K0.6171.00
231_D237_G0.6151.00
149_E374_H0.6141.00
182_R342_V0.6121.00
212_F216_P0.6111.00
382_K386_V0.6091.00
107_I382_K0.6081.00
22_T107_I0.6081.00
266_L275_A0.6051.00
210_A255_A0.6031.00
129_I134_L0.6031.00
147_Q150_D0.6031.00
194_V210_A0.6021.00
64_N159_I0.6021.00
138_Y168_E0.6011.00
245_F261_S0.6001.00
84_T110_R0.5971.00
121_S173_T0.5971.00
227_R278_E0.5961.00
54_F142_V0.5951.00
150_D154_L0.5931.00
62_M158_Y0.5931.00
172_S175_P0.5921.00
212_F219_G0.5921.00
277_D284_A0.5921.00
79_D143_T0.5891.00
329_V341_V0.5881.00
208_D304_G0.5871.00
108_G379_K0.5851.00
172_S362_V0.5851.00
252_C265_R0.5841.00
243_E259_A0.5841.00
24_F123_V0.5841.00
40_R47_E0.5821.00
322_H361_P0.5821.00
179_Q343_D0.5811.00
217_I282_L0.5811.00
80_A122_M0.5811.00
370_E373_A0.5801.00
201_G240_T0.5801.00
359_G363_I0.5791.00
201_G242_S0.5791.00
372_E379_K0.5761.00
96_D100_G0.5751.00
34_E106_L0.5751.00
179_Q341_V0.5751.00
28_M120_A0.5711.00
364_G368_G0.5701.00
157_Q160_I0.5681.00
194_V305_L0.5681.00
184_Q349_T0.5681.00
262_I279_I0.5681.00
325_V361_P0.5651.00
78_M171_V0.5651.00
243_E248_S0.5641.00
38_E147_Q0.5641.00
232_E235_G0.5641.00
31_I103_T0.5621.00
87_I109_G0.5601.00
42_V59_I0.5601.00
245_F257_S0.5591.00
120_A124_Y0.5591.00
66_L164_G0.5581.00
180_V187_R0.5571.00
181_Y188_M0.5571.00
66_L143_T0.5571.00
25_L120_A0.5551.00
49_M54_F0.5541.00
124_Y128_I0.5521.00
172_S177_D0.5511.00
363_I367_P0.5501.00
324_T327_A0.5481.00
75_L166_R0.5481.00
94_D98_Y0.5461.00
314_P357_R0.5461.00
284_A287_K0.5451.00
208_D302_W0.5451.00
37_D106_L0.5451.00
79_D145_T0.5441.00
192_I307_Y0.5431.00
160_I163_S0.5421.00
213_K216_P0.5421.00
221_L241_V0.5421.00
22_T386_V0.5391.00
175_P367_P0.5381.00
243_E249_P0.5341.00
224_L227_R0.5341.00
102_E107_I0.5331.00
25_L382_K0.5301.00
179_Q184_Q0.5291.00
264_R279_I0.5291.00
215_G222_Q0.5261.00
31_I41_V0.5261.00
115_Q119_M0.5251.00
269_G356_G0.5231.00
369_K379_K0.5211.00
154_L157_Q0.5211.00
36_C40_R0.5191.00
210_A254_V0.5171.00
143_T170_V0.5171.00
181_Y343_D0.5161.00
192_I262_I0.5151.00
167_P170_V0.5151.00
171_V174_E0.5141.00
386_V389_A0.5131.00
178_C184_Q0.5121.00
20_D51_K0.5111.00
68_Y75_L0.5111.00
329_V340_P0.5111.00
24_F52_V0.5111.00
49_M126_G0.5091.00
283_P307_Y0.5091.00
336_F387_T0.5091.00
21_M25_L0.5081.00
133_G136_D0.5081.00
232_E343_D0.5071.00
192_I279_I0.5061.00
34_E87_I0.5051.00
76_V171_V0.5051.00
19_A22_T0.5041.00
244_I260_V0.5041.00
190_I309_T0.5031.00
91_K94_D0.5021.00
198_S376_P0.5001.00
217_I221_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3pfoA 2 0.9653 100 0.197 Contact Map
3iszA 2 0.8933 100 0.244 Contact Map
4pqaA 2 0.9057 100 0.248 Contact Map
4mmoA 2 0.9132 100 0.264 Contact Map
1cg2A 4 0.9231 100 0.264 Contact Map
4g1pA 2 0.9677 100 0.266 Contact Map
2pokA 2 0.9529 100 0.271 Contact Map
3rzaA 2 0.8834 100 0.274 Contact Map
4q7aA 5 0.8809 100 0.274 Contact Map
3dljA 2 0.9653 100 0.276 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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