GREMLIN Database
YPFJ - Uncharacterized protein YpfJ
UniProt: P64429 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14197
Length: 287 (261)
Sequences: 1852 (1365)
Seq/√Len: 84.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
179_I209_F4.4971.00
106_Q137_G4.2011.00
281_N284_G4.0371.00
120_G135_A3.5191.00
119_T124_G3.3191.00
148_D152_K3.1651.00
276_D279_Q3.1431.00
34_G37_G3.0441.00
208_C280_C2.9791.00
158_D230_E2.8041.00
42_I46_V2.7311.00
180_E202_M2.7271.00
262_Q266_S2.6441.00
141_I146_Y2.5321.00
183_V198_L2.3511.00
256_F260_T2.3481.00
95_G107_Q2.3481.00
269_K273_D2.2391.00
174_Q205_Q2.1821.00
194_E197_R2.1801.00
43_V47_A2.1531.00
274_S279_Q2.1021.00
212_V277_P1.9141.00
15_R111_V1.9021.00
155_A234_A1.8591.00
90_T169_V1.8481.00
105_Y169_V1.8421.00
267_W282_T1.8391.00
248_Q252_V1.8261.00
44_V49_Y1.7981.00
234_A238_I1.7971.00
50_Y53_D1.7771.00
125_Q128_M1.7761.00
266_S270_R1.7591.00
124_G128_M1.7381.00
117_T124_G1.7011.00
148_D242_R1.6961.00
137_G175_K1.6961.00
197_R201_R1.6901.00
183_V202_M1.6891.00
91_E108_P1.6841.00
106_Q176_L1.6611.00
191_T194_E1.6431.00
176_L179_I1.6431.00
243_L247_S1.6421.00
32_P35_K1.6271.00
114_R147_D1.6251.00
228_L272_F1.6151.00
34_G38_L1.5951.00
85_V89_T1.5901.00
98_F103_K1.5841.00
73_S77_D1.5811.00
175_K180_E1.5741.00
42_I45_L1.5611.00
177_L209_F1.5571.00
31_L37_G1.5491.00
77_D80_A1.5361.00
31_L34_G1.5301.00
265_Y269_K1.5141.00
229_E265_Y1.5070.99
93_T97_Q1.5030.99
88_A91_E1.4790.99
36_G40_L1.4770.99
29_F32_P1.4760.99
117_T128_M1.4640.99
41_L45_L1.4550.99
72_I77_D1.4520.99
242_R246_Q1.4210.99
180_E184_R1.4190.99
233_N237_A1.4040.99
207_D264_R1.4030.99
215_H219_Q1.3870.99
270_R279_Q1.3730.99
232_L236_Q1.3640.99
105_Y139_V1.3520.99
46_V49_Y1.3490.99
35_K39_I1.3490.99
267_W283_F1.3480.99
44_V51_G1.3470.99
83_T110_L1.3120.99
14_D17_N1.3100.99
237_A242_R1.3060.99
17_N114_R1.3020.98
96_Q100_K1.2910.98
113_Y117_T1.2890.98
201_R266_S1.2860.98
66_Q69_T1.2770.98
217_M222_V1.2710.98
226_G230_E1.2680.98
48_G51_G1.2680.98
30_R33_S1.2660.98
205_Q209_F1.2570.98
231_A268_F1.2510.98
113_Y124_G1.2340.98
47_A51_G1.2170.98
83_T165_I1.2100.98
97_Q100_K1.2100.98
226_G229_E1.2050.97
147_D151_D1.1900.97
116_M123_A1.1870.97
32_P36_G1.1800.97
30_R34_G1.1790.97
46_V50_Y1.1780.97
40_L43_V1.1740.97
199_S202_M1.1720.97
15_R117_T1.1680.97
87_L110_L1.1670.97
246_Q249_G1.1340.96
41_L44_V1.1310.96
51_G54_L1.1250.96
141_I165_I1.1250.96
101_M277_P1.1220.96
38_L42_I1.1190.96
45_L51_G1.1140.96
153_L243_L1.1080.96
80_A84_S1.1050.96
109_K138_T1.1050.96
159_F214_G1.1020.96
93_T212_V1.0960.96
172_H176_L1.0900.95
245_Q250_R1.0880.95
117_T125_Q1.0780.95
184_R202_M1.0770.95
70_R76_E1.0570.95
182_K185_Q1.0560.95
86_I162_G1.0430.94
270_R273_D1.0270.94
244_Q249_G1.0200.93
175_K181_P1.0150.93
31_L35_K1.0120.93
201_R267_W1.0110.93
39_I42_I1.0050.93
43_V46_V1.0030.93
93_T277_P0.9920.93
56_G59_T0.9910.92
35_K46_V0.9870.92
208_C279_Q0.9860.92
81_K85_V0.9790.92
40_L44_V0.9790.92
269_K272_F0.9780.92
195_V199_S0.9750.92
177_L277_P0.9740.92
260_T263_Q0.9730.92
180_E183_V0.9470.91
34_G44_V0.9430.91
149_M153_L0.9390.90
72_I80_A0.9260.90
171_H203_E0.9250.90
175_K202_M0.9200.89
270_R274_S0.9140.89
167_H171_H0.9110.89
225_T273_D0.9110.89
30_R37_G0.9080.89
209_F212_V0.9060.89
252_V255_S0.8960.88
149_M156_D0.8900.88
167_H203_E0.8880.88
89_T222_V0.8850.87
46_V52_V0.8830.87
123_A126_S0.8830.87
85_V88_A0.8790.87
45_L49_Y0.8780.87
75_N80_A0.8760.87
157_G234_A0.8720.87
108_P169_V0.8710.87
242_R245_Q0.8690.87
44_V47_A0.8660.86
238_I243_L0.8540.86
228_L232_L0.8520.85
173_V177_L0.8520.85
90_T105_Y0.8490.85
268_F272_F0.8460.85
185_Q189_N0.8420.85
224_E229_E0.8420.85
243_L246_Q0.8400.85
62_P66_Q0.8350.84
201_R281_N0.8350.84
21_G41_L0.8310.84
121_C133_C0.8270.84
47_A50_Y0.8250.84
267_W281_N0.8250.84
111_V119_T0.8230.83
113_Y142_D0.8190.83
41_L46_V0.8170.83
118_R123_A0.8150.83
109_K139_V0.8140.83
108_P175_K0.8120.83
44_V50_Y0.8100.82
99_E104_T0.8060.82
223_L227_D0.8040.82
37_G47_A0.7990.82
18_S22_P0.7970.81
236_Q265_Y0.7940.81
49_Y53_D0.7920.81
30_R35_K0.7810.80
36_G44_V0.7790.80
225_T229_E0.7780.80
195_V280_C0.7770.80
120_G136_D0.7770.80
73_S80_A0.7680.79
161_Q280_C0.7680.79
77_D81_K0.7650.79
82_F162_G0.7640.79
38_L53_D0.7600.78
156_D233_N0.7600.78
36_G45_L0.7570.78
32_P37_G0.7570.78
73_S76_E0.7560.78
227_D230_E0.7550.78
37_G41_L0.7520.77
161_Q238_I0.7480.77
156_D230_E0.7460.77
183_V199_S0.7460.77
167_H258_H0.7450.77
22_P29_F0.7450.77
245_Q248_Q0.7410.76
84_S88_A0.7380.76
35_K41_L0.7340.76
232_L269_K0.7340.76
168_E171_H0.7290.75
249_G252_V0.7290.75
103_K177_L0.7290.75
39_I43_V0.7260.75
202_M283_F0.7260.75
153_L247_S0.7160.74
51_G55_T0.7160.74
75_N79_A0.7140.74
18_S30_R0.7100.73
57_L60_G0.7090.73
168_E203_E0.7020.73
88_A92_D0.7010.72
245_Q251_V0.7010.72
168_E258_H0.6980.72
37_G42_I0.6960.72
91_E110_L0.6950.72
44_V54_L0.6940.72
89_T217_M0.6900.71
72_I76_E0.6870.71
163_Y235_A0.6870.71
208_C274_S0.6870.71
146_Y150_K0.6810.70
137_G176_L0.6780.70
129_G264_R0.6710.69
38_L45_L0.6670.69
161_Q208_C0.6670.69
18_S67_Q0.6640.68
149_M157_G0.6630.68
51_G77_D0.6620.68
67_Q70_R0.6610.68
198_L202_M0.6580.68
34_G45_L0.6560.67
147_D150_K0.6510.67
157_G164_V0.6500.67
155_A230_E0.6490.67
120_G127_I0.6480.66
149_M234_A0.6480.66
86_I169_V0.6470.66
159_F162_G0.6470.66
62_P67_Q0.6450.66
114_R144_S0.6440.66
195_V208_C0.6440.66
38_L41_L0.6440.66
214_G228_L0.6420.66
33_S37_G0.6410.66
108_P137_G0.6410.66
50_Y55_T0.6410.66
223_L228_L0.6400.65
218_Q222_V0.6370.65
152_K246_Q0.6370.65
111_V138_T0.6370.65
48_G52_V0.6370.65
33_S36_G0.6340.65
15_R18_S0.6330.65
171_H258_H0.6320.64
33_S44_V0.6320.64
237_A257_T0.6300.64
136_D235_A0.6220.63
215_H218_Q0.6210.63
38_L250_R0.6200.63
203_E258_H0.6190.63
143_L155_A0.6180.63
34_G40_L0.6130.62
129_G207_D0.6100.62
69_T72_I0.6090.62
159_F231_A0.6090.62
110_L169_V0.6080.62
63_V67_Q0.6080.62
214_G272_F0.6070.61
96_Q99_E0.6040.61
148_D153_L0.6030.61
181_P185_Q0.6020.61
277_P280_C0.6000.60
231_A272_F0.6000.60
31_L36_G0.6000.60
115_G143_L0.6000.60
264_R268_F0.5990.60
70_R73_S0.5990.60
143_L146_Y0.5960.60
64_S67_Q0.5930.60
65_Q68_S0.5910.59
49_Y280_C0.5900.59
139_V169_V0.5880.59
232_L265_Y0.5830.58
98_F173_V0.5820.58
79_A84_S0.5820.58
173_V176_L0.5810.58
156_D161_Q0.5800.58
37_G55_T0.5800.58
97_Q277_P0.5800.58
90_T108_P0.5790.58
37_G45_L0.5770.58
159_F230_E0.5760.57
184_R192_Q0.5750.57
101_M276_D0.5740.57
79_A83_T0.5740.57
135_A180_E0.5740.57
79_A85_V0.5730.57
149_M152_K0.5730.57
136_D140_Y0.5720.57
65_Q69_T0.5720.57
87_L90_T0.5720.57
50_Y57_L0.5700.57
88_A110_L0.5700.57
156_D260_T0.5690.56
44_V53_D0.5690.56
241_D264_R0.5670.56
33_S43_V0.5670.56
254_D257_T0.5660.56
126_S144_S0.5650.56
129_G172_H0.5630.56
193_A197_R0.5620.56
74_P77_D0.5620.56
40_L54_L0.5600.55
76_E79_A0.5580.55
19_S67_Q0.5580.55
164_V238_I0.5570.55
146_Y213_W0.5560.55
37_G40_L0.5550.55
170_G209_F0.5530.54
53_D58_M0.5520.54
247_S250_R0.5500.54
18_S21_G0.5460.53
216_S220_Q0.5460.53
149_M164_V0.5440.53
145_F235_A0.5430.53
49_Y208_C0.5430.53
72_I75_N0.5420.53
146_Y161_Q0.5420.53
45_L53_D0.5420.53
141_I150_K0.5420.53
31_L45_L0.5410.53
212_V216_S0.5400.53
100_K216_S0.5370.52
62_P65_Q0.5370.52
102_G265_Y0.5370.52
105_Y173_V0.5340.52
47_A59_T0.5330.52
198_L201_R0.5310.51
80_A112_M0.5300.51
84_S91_E0.5290.51
89_T93_T0.5290.51
20_G192_Q0.5290.51
175_K184_R0.5290.51
253_P260_T0.5280.51
217_M221_G0.5270.51
31_L44_V0.5260.51
235_A238_I0.5250.51
222_V243_L0.5230.50
69_T73_S0.5220.50
20_G247_S0.5190.50
46_V53_D0.5180.50
98_F101_M0.5170.50
222_V272_F0.5160.49
113_Y207_D0.5150.49
32_P47_A0.5130.49
35_K42_I0.5120.49
97_Q212_V0.5110.49
55_T60_G0.5100.49
47_A53_D0.5100.49
113_Y125_Q0.5080.48
142_D207_D0.5070.48
69_T95_G0.5050.48
42_I49_Y0.5040.48
34_G52_V0.5040.48
38_L43_V0.5030.48
35_K50_Y0.5030.48
123_A127_I0.5030.48
75_N78_E0.5020.48
31_L47_A0.5020.48
213_W235_A0.5020.48
40_L55_T0.5000.47
135_A184_R0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3c37A 1 0.6481 96.8 0.913 Contact Map
4il3A 1 0.7631 96.8 0.913 Contact Map
4aw6A 2 0.7491 96.4 0.918 Contact Map
3cqbA 4 0.3589 94.8 0.927 Contact Map
4qhjA 2 0.3693 81.1 0.945 Contact Map
3dteA 2 0.5749 71.4 0.949 Contact Map
4jixA 2 0.3798 56.2 0.954 Contact Map
4jiuA 1 0.3554 50.8 0.955 Contact Map
1c7kA 1 0.4425 48.7 0.956 Contact Map
2ejqA 1 0.4007 44.2 0.957 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0089 seconds.